Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainVWC

KCP MUC5AC PXDNL

4.68e-0528473PF00093
DomainWxxW_domain

CILP2 MUC5AC

9.24e-056472IPR025155
DomainMucin2_WxxW

CILP2 MUC5AC

9.24e-056472PF13330
DomainVWFC_1

KCP MUC5AC PXDNL

1.01e-0436473PS01208
DomainVWC

KCP MUC5AC PXDNL

1.18e-0438473SM00214
DomainVWFC_2

KCP MUC5AC PXDNL

1.18e-0438473PS50184
DomainVWF_dom

KCP MUC5AC PXDNL

1.60e-0442473IPR001007
DomainUnchr_dom_Cys-rich

KCP MUC5AC

4.75e-0413472IPR014853
DomainC8

KCP MUC5AC

4.75e-0413472SM00832
DomainTIL_dom

KCP MUC5AC

5.53e-0414472IPR002919
DomainLIM

TGFB1I1 TRIP6 PDLIM2

6.97e-0469473PF00412
Domain-

TGFB1I1 TRIP6 PDLIM2

7.26e-04704732.10.110.10
DomainVWD

KCP MUC5AC

7.27e-0416472SM00216
DomainEMI_domain

EGFL7 MEGF6

7.27e-0416472IPR011489
DomainVWF_type-D

KCP MUC5AC

7.27e-0416472IPR001846
DomainVWFD

KCP MUC5AC

7.27e-0416472PS51233
DomainVWD

KCP MUC5AC

7.27e-0416472PF00094
DomainZnf_LIM

TGFB1I1 TRIP6 PDLIM2

7.57e-0471473IPR001781
DomainLIM_DOMAIN_1

TGFB1I1 TRIP6 PDLIM2

7.57e-0471473PS00478
DomainLIM_DOMAIN_2

TGFB1I1 TRIP6 PDLIM2

7.57e-0471473PS50023
DomainLIM

TGFB1I1 TRIP6 PDLIM2

7.57e-0471473SM00132
DomainEMI

EGFL7 MEGF6

8.23e-0417472PS51041
DomainVWC_out

KCP MUC5AC

1.03e-0319472SM00215
DomainKRAB

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316

1.99e-03358475PS50805
DomainKRAB

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316

1.99e-03358475PF01352
DomainKRAB

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316

2.27e-03369475SM00349
DomainKRAB

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316

2.30e-03370475IPR001909
DomainLaminin_EGF

LAMB3 MEGF6

3.50e-0335472PF00053
DomainEGF_Lam

LAMB3 MEGF6

3.50e-0335472SM00180
DomainLaminin_EGF

LAMB3 MEGF6

4.11e-0338472IPR002049
Domain-

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316 ZNF646

6.82e-036794763.30.160.60
Domainzf-C2H2

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316 ZNF646

7.51e-03693476PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316 ZNF646

7.56e-03694476IPR013087
DomainEGF_extracell

EGFL7 MEGF6

1.00e-0260472IPR013111
DomainEGF_2

EGFL7 MEGF6

1.00e-0260472PF07974
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

MMP27 RTEL1 MUC5AC SPINK5

2.90e-067148433541421
Pubmed

Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5.

TGFB1I1 TRIP6

1.12e-05448223145173
Pubmed

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins.

HJV P4HA2 ZNF517 PXDNL ZNF559 ZNF646 CCER1

1.37e-0483248736724073
Pubmed

Meta-analysis of Parkinson's disease: identification of a novel locus, RIT2.

CNKSR3 ZNF646

1.68e-041448222451204
Pubmed

Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.

SOX5 SCAP

2.81e-041848229899135
Pubmed

An empirical framework for binary interactome mapping.

REX1BD LOXL4 TRIP6 ZNF646

2.93e-0423148419060904
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

JCAD SCAP TRIM47 TRIP6 KIFC2 KLHL21

5.75e-0475448635906200
Pubmed

DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.

JCAD HNRNPUL1 SLC25A1

6.49e-0412248330773093
Pubmed

Biosynthesis of triacylglycerols.

GPAT4 SLC25A1

6.89e-04284828944226
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LAMB3 SCAP MEGF6 GPAT4 KIFC2 KLHL21 ZNF316

7.57e-04110548735748872
Pubmed

Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.

HNRNPUL1 TRIM47

9.01e-043248219542561
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

TGFB1I1 SOX5 EGFL7 HNRNPUL1 MEGF6

1.03e-0356048521653829
Pubmed

Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis.

PNKD SLC25A1 NDUFS8

1.09e-0314648329509794
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

JCAD HNRNPUL1 TRIP6 SLC25A1 SYDE2 CNKSR3

1.14e-0386148636931259
GeneFamilyLIM domain containing

TGFB1I1 TRIP6 PDLIM2

1.26e-04593031218
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZIK1 ZNF517 ZNF548 ZNF559 ZNF316 ZNF646

1.01e-0371830628
CoexpressionNABA_MATRISOME

MMP27 KCP LAMB3 LOXL4 P4HA2 CILP2 EGFL7 MEGF6 MUC5AC PXDNL

1.36e-0510264810M5889
CoexpressionHOOI_ST7_TARGETS_UP

JCAD LAMB3 MEGF6 TRIP6

2.56e-0593484M8455
CoexpressionGSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_UP

BCLAF3 TGFB1I1 LAMB3 SCAP RTEL1

3.23e-05200485M9397
CoexpressionGSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP

REX1BD HNRNPUL1 PDLIM2 SLC25A1 NDUFS8

3.23e-05200485M5781
CoexpressionFIGUEROA_AML_METHYLATION_CLUSTER_1_UP

JCAD HTR2A GPAT4 SYDE2

7.42e-05122484M2159
CoexpressionNABA_MATRISOME

MMP27 KCP LAMB3 LOXL4 P4HA2 CILP2 EGFL7 MEGF6 MUC5AC

7.71e-051008489MM17056
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 LOXL4 CILP2 TRIM47 KLHL21

2.30e-061984853575620db5aeaeb0bdcd7a8ff65c43abd3fa13e4
ToppCellmetastatic_Brain|World / Location, Cell class and cell subclass

LAMB3 P4HA2 EGFL7 TRIP6 SPINK5

2.36e-06199485a6793145de96bcdbfd4fe04159e34ea2244ca5a8
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA22 MEGF6 LHFPL1 ZNF316

1.66e-051424845690eee2ce1ecd02e34eac4193578bd13c4228b9
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 LOXL4 CILP2 CCER1

3.85e-0517648477c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCellfacs-Heart-LA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 MEGF6 TRIM47

4.87e-051874847b13c3b67d66f3afb410141d5471c9e78a4d8623
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 MEGF6 TRIM47

4.87e-05187484d9943e65eedab73d141eae524e2411653a751705
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

SOX5 LAMB3 LOXL4 SPINK5

5.18e-05190484ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV ALPK3 LAMB3 CILP2

5.40e-051924841a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV ALPK3 LAMB3 CILP2

5.40e-05192484f6a4e348406a852ace9fb21db8fbdff539217645
ToppCelldroplet-Tongue-nan-3m-Epithelial-keratinocyte|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDLIM2 LHFPL1 CNKSR3 SPINK5

5.62e-05194484592e8c4b73ba424a52305ac411ea9c0a2dc44467
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 LOXL4 CILP2 TRIM47

5.97e-051974846e111ba16fc8adde782b3f7da250248cddf11228
ToppCell(2)_Fibroblasts-(23)_Fibro-4|World / Cell class and subclass of bone marrow stroma cells in homeostatis

P4HA2 CILP2 UTS2R TRIM47

5.97e-05197484a183919023a4aca90a06be0e5e89c817b38c5574
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 LOXL4 CILP2 TRIM47

5.97e-05197484ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB1I1 JCAD EGFL7 SH2D5

5.97e-0519748415d1e0dffee8f5ba8cee37adfbfa0551a0cd5e15
ToppCelldroplet-Trachea-nan-3m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 LOXL4 TRIM47 KLHL21

5.97e-051974848786125b669d5d0b15e12df0ade6b319f09f7333
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 LOXL4 CILP2 TRIM47

5.97e-051974844b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCellBronchial_Brush-Epithelial-Basal_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMB3 LOXL4 MEGF6 SPINK5

5.97e-05197484f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCellBronchial_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMB3 LOXL4 MEGF6 SPINK5

6.08e-0519848410a17d7c116dcd6cf847fe6f5d7196d887cad1f9
ToppCellfacs-Trachea-nan-3m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX5 LOXL4 CILP2 TRIM47

6.08e-0519848471e847e8c24744d6df4a960348ad2ecf310373b4
ToppCelldroplet-Trachea|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LOXL4 CILP2 TRIM47 KLHL21

6.20e-051994841c7d30765ddb2291967da5d15664c6238c680c1d
ToppCelldroplet-Trachea|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LOXL4 CILP2 TRIM47 KLHL21

6.20e-05199484b9038a1ccf3ef3123e2e39afbe6213c363437443
ToppCellBasal|World / shred by cell class for turbinate

TGFB1I1 LAMB3 LOXL4 SPINK5

6.20e-05199484d9fe184a7d3251f871eba3123e0127aa1a6f2949
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB3 LOXL4 TRIP6 SPINK5

6.33e-05200484ea1325ca6039c6d2318b1ceb9d396399bb21b670
ToppCellproximal-Epithelial-Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMB3 LOXL4 TRIP6 SPINK5

6.33e-05200484c6a491d3e2dae6618f25dc3c9aac08f657348168
ToppCellproximal-Epithelial-Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMB3 LOXL4 TRIP6 SPINK5

6.33e-05200484f5d48f521abbd1e07de05f2b3768ad2f9675f1e1
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_basal-Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB3 LOXL4 TRIP6 SPINK5

6.33e-052004848c8a631b9892f6594857a27e020b43aae3afcaac
ToppCellproximal-3-Epithelial-Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMB3 LOXL4 TRIP6 SPINK5

6.33e-052004848083047c213488e40b975013e3c5c43f7c0c15b2
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LOXL4 EGFL7 ZNF316

1.87e-04103483eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

MEGF6 ZNF517 SYDE2

2.15e-04108483ee924deacd14ea404fda80ed633960143fd474c0
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2-Mgp|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LOXL4 CILP2 SPATA22

3.23e-04124483b0ed84522180f8cea541461faf7882c57abf8cd4
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

LOXL4 CILP2 SPATA22

3.23e-04124483231862f849d8ab73c6a44c782d33ef2f07661baf
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SPATA22 LHFPL1 ZNF316

4.05e-0413448364979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EGFL7 HTR2A MEGF6

5.63e-0415048396b160f163030fbf48aedc37d6ae224e11492c52
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB3 LOXL4 SPINK5

5.96e-0415348382b77c8bae49dd63b8f10eb67df66ca71d0bb315
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZIK1 HTR2A

5.96e-041534833b1b0cc8e9dd2b1484649789330713282ee44414
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EGFL7 HTR2A SLC25A1

6.31e-04156483ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EGFL7 HTR2A SLC25A1

6.31e-04156483586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TGFB1I1 SPATA22 PXDNL

6.67e-041594837a5c94c87b73f928d4daee507f32cbe7d90e4478
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP EGFL7 MEGF6

7.42e-041654837d319a112b9062efee428bef6f4534d2ce782e04
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MEGF6 ZNF517 SYDE2

7.55e-041664838d5d09f25e8903d481c2097fed435e69d42ccdb5
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P4HA2 MEGF6 TRIM47

7.68e-04167483f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

P4HA2 MEGF6 TRIM47

7.68e-041674835fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SOX5 LOXL4 CILP2

7.68e-04167483102b3d160a44c8623fab1fd10e9054178c42a78b
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

DNHD1 HTR2A MUC5AC

7.95e-04169483dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

LOXL4 SCAP LHFPL1

7.95e-04169483150c08c7b1dc0f46173a7b8f6a3fc70d82906c0d
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

ZNF517 ZNF559 SYDE2

8.09e-04170483aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMB3 LOXL4 SPINK5

8.37e-04172483e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

DNHD1 HTR2A MUC5AC

8.37e-04172483f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LAMB3 LOXL4 MUC5AC

8.37e-041724830be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

EGFL7 SH2D5 CNKSR3

8.51e-04173483dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellAT1_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

LAMB3 P4HA2 SH2D5

8.51e-04173483b29816427428c7053017477f59b828bf1357f3b2
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

TGFB1I1 JCAD EGFL7

8.65e-04174483d551bc29afef071adf4c9bb80345352ec33441d8
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

LAMB3 CILP2 LHFPL1

8.65e-04174483a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LOXL4 EGFL7 MEGF6

8.80e-041754832e54961846c65b185d9bd6e305dd81205579d890
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LOXL4 EGFL7 MEGF6

8.80e-04175483efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 JCAD EGFL7

8.94e-0417648364e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-chondrocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SOX5 LOXL4 CILP2

9.09e-04177483915b848d789051a1c3bc6f6dc86955bb752276ab
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGFL7 MEGF6 TRIM47

9.09e-041774836f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB3 LOXL4 SPINK5

9.09e-041774839e65b39fd797b6ce204b6480415810d1923acee5
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

OTUD4 JCAD EGFL7

9.24e-04178483ea10117026021c959ffc871fc377cdb3e161d264
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD LOXL4 EGFL7

9.39e-041794839fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZIK1 MEGF6

9.39e-04179483b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCelldroplet-Kidney-nan-21m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 TRIM47

9.39e-04179483ba38177ffcf3a20f02afeeaaa91bc8eab8d1ac05
ToppCelldroplet-Kidney-nan-21m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 TRIM47

9.39e-04179483d121351b4c3b91108e6c5753d18a44d676f38d4c
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SOX5 LAMB3 LOXL4

9.54e-0418048349829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCell368C-Endothelial_cells-Endothelial-E|368C / Donor, Lineage, Cell class and subclass (all cells)

JCAD EGFL7 RTEL1

9.54e-041804838ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

PNKD ZNF517 ZNF316

9.54e-04180483c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCell368C-Endothelial_cells-Endothelial-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

JCAD EGFL7 RTEL1

9.54e-04180483394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCellsevere-CD8+_T_naive|severe / disease stage, cell group and cell class

DNHD1 TRIP6 ZNF548

9.54e-0418048394fe530367b170777f4051a4034cff06d80dbb83
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALPK3 JCAD EGFL7

9.54e-0418048397e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCellfacs-Thymus-Epithelium-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 TRIM47

9.70e-04181483bce56e12ab93693c9c04fa6aad8f2e1dff0c4d45
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EGFL7 MEGF6 TRIM47

9.70e-041814832c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCellsevere-CD8+_T_naive|World / disease stage, cell group and cell class

DNHD1 TRIP6 ZNF548

9.70e-0418148369eeeb7f326e230b07495d557f708fbe3312ac0a
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Hpcal4_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RBMXL2 LHFPL1

9.79e-044348205de4f11e7315dce19efed14605d7e1704d61b3a
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Hpcal4_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RBMXL2 LHFPL1

9.79e-0443482ba1a8fd3119a26b65722898276045bf5ecf59768
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Hpcal4_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

RBMXL2 LHFPL1

9.79e-0443482f1e6e1c386851e773f8aa44f112ebf7fdb887df1
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 JCAD EGFL7

9.85e-04182483f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellfacs-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ZIK1 TRIM47

1.00e-0318348312e876d6205af8aad74265c668b5e95b9e7487f3
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGFL7 MEGF6 TRIM47

1.00e-03183483fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD EGFL7 SPINK5

1.02e-03184483fa38d6a8709f520a027ad7e3ff783c84187ec467
ToppCellfacs-Heart-RA-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV LAMB3 SYDE2

1.02e-0318448372b42dfca7e9c0257f11d8242531e843271871a7
ToppCelldroplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TGFB1I1 EGFL7 TRIM47

1.02e-03184483087666ba949b129c53d7ace40f9e543e3875a7de
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

EGFL7 MEGF6 TRIM47

1.02e-03184483b4c561924c508536fd2112e91e32176b95fdf63a
ToppCellfacs-Heart-RA-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV LAMB3 SYDE2

1.02e-03184483c6f4537ae8b6e8fde1be17df14629b7b49b4997c
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALPK3 JCAD EGFL7

1.02e-03184483842473fa415575441b595073a994b6d621169776
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|normal_Lung / Location, Cell class and cell subclass

JCAD EGFL7 TRIM47

1.02e-031844837ee98acda030366ac6cf3890a6d93fd0426712ed
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD EGFL7 LHFPL1

1.03e-031854839de1db2ce9e44956b1214daf6e1e161334679c88
ToppCellcellseq-Epithelial-Epithelial_Glandular-MEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TGFB1I1 LAMB3 LOXL4

1.03e-031854830595e7ab37eed690f6e3d16a9a4e9a4bce2b89db
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD EGFL7 SPINK5

1.03e-031854830ab1be455f2cd883c9d1522ca78112c37833352e
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD EGFL7 LHFPL1

1.03e-0318548318f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCellcellseq-Epithelial-Epithelial_Glandular-MEC-MEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TGFB1I1 LAMB3 LOXL4

1.03e-0318548376304829fcfb5934188933ca20d33bc8c8b0dc91
ToppCelldroplet-Heart-nan-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 HNRNPUL1

1.05e-031864830ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-chondrocyte|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SOX5 LOXL4 CILP2

1.05e-0318648380a0a42ca8585cdb1dda57a18c254316a126ee64
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV LAMB3 CILP2

1.05e-03186483337f768cc43db2db96ba6495b076006b1a5b0331
ToppCelldroplet-Lung-nan-21m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB1I1 EGFL7 TRIM47

1.05e-031864835d0cd07b6b51e8ce9e1da949f757dc4575ec5752
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJV LAMB3 CILP2

1.05e-03186483e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCellmegakaryocytic-Megakaryocyte|World / Lineage and Cell class

TGFB1I1 EGFL7 HTR2A

1.05e-03186483acd15a169b6122b28cc99ef34de10701edcfedfe
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 TRIM47

1.06e-03187483965584ee44669a72866a20ddf7f657bc5a7f7a8b
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 TRIM47

1.06e-03187483a7ef179e6561e17cafae10e1843bf82ac3ae0c89
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD EGFL7 TRIM47

1.06e-031874833e25c15fa29f8c738044914e8b3420d5713f18d9
DrugDoxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A

TGFB1I1 LAMB3 EGFL7 MEGF6 RTEL1 SLC25A1

3.42e-061964865671_UP
Diseaseresponse to acetylsalicylate

SCAP CNKSR3

2.94e-0416472GO_1903492
Diseasemitochondrial metabolism disease (implicated_via_orthology)

SLC25A1 NDUFS8

1.43e-0335472DOID:700 (implicated_via_orthology)
Diseaseidiopathic pulmonary fibrosis

RTEL1 MUC5AC

3.75e-0357472EFO_0000768
Diseasecoronary artery disease, plasminogen activator inhibitor 1 measurement

JCAD HNRNPUL1

4.56e-0363472EFO_0001645, EFO_0004792
Diseaseinflammatory bowel disease

SOX5 KCP P4HA2 PNKD

5.63e-03449474EFO_0003767
Diseasecarotid artery intima media thickness

SOX5 JCAD LOXL4 SPATA22

5.67e-03450474EFO_0007117
Diseasecortical surface area measurement, neuroimaging measurement

SOX5 MEGF6 CNKSR3

5.68e-03227473EFO_0004346, EFO_0010736

Protein segments in the cluster

PeptideGeneStartEntry
EHAYRPGRRVCAVRA

EGFL7

21

Q9UHF1
QRSIHREPGSYTGRR

HTR2A

296

P28223
GPLQTRRYCRHQGRQ

ALPK3

101

Q96L96
EVRGCRLRGQYFPHN

DNHD1

661

Q96M86
SSCHRRRPGAPAYNR

CCER1

36

Q8TC90
QYHRNVRGRPFRGDR

OTUD4

1086

Q01804
DPCDYEGRFSRLHGR

HJV

146

Q6ZVN8
RTRVHGRCPRYFDGP

MMP27

161

Q9H306
GPIHLSEVRCRGYER

LOXL4

371

Q96JB6
RHYVRNGRLPCTREN

SPINK5

571

Q9NQ38
HPPTGNDQAYRRRGR

JCAD

106

Q9P266
TFRRCNYPVRGEGHS

LHFPL1

46

Q86WI0
ENLRAHGYRVCESPR

MUC5AC

1411

P98088
RGEHALRRYPSGEER

NDUFS8

96

O00217
RSGEGDYRTRHAACP

P4HA2

491

O15460
AAATCEYPRRLHGRA

PXDNL

206

A1KZ92
RRPCDRSNGYGRTEC

CHD9

1481

Q3L8U1
QAARYDRHDRGPCPR

KLHL21

261

Q9UJP4
HRGYSPGRGDSNRRA

BCLAF3

96

A2AJT9
YHDRENRPRNGGICV

GPAT4

231

Q86UL3
ERCQLHYFRNRRPGA

LAMB3

356

Q13751
RHRAVCGRSRDSPGY

SCAP

896

Q12770
PGGTVTTCYRGRHRR

KIFC2

431

Q96AC6
RGYFEHREDRRGRSP

HNRNPUL1

181

Q9BUJ2
GYRLHEDRRGCSPLE

MEGF6

441

O75095
CGYRPEHSIPRRQRA

RTEL1

976

Q9NZ71
GAAYRRACPRDGERG

SYDE2

36

Q5VT97
EPYDRGRLGRNAHSC

TRIM47

506

Q96LD4
RRHRDCRVYGSPQDG

PNKD

186

Q8N490
RLIRGRVHRCVGNYD

SPATA22

306

Q8NHS9
GREVDPCRAAGYRAR

KCP

1391

Q6ZWJ8
SEGRARHARLGNPYC

SH2D5

216

Q6ZV89
QRDSYSRSGCRVPRG

RBMXL2

361

O75526
QAVRIQEGRYRHPGC

PDLIM2

296

Q96JY6
REQPRGRRCSNYHVR

CILP2

126

Q8IUL8
RHLVRGADYIRGSRC

CNKSR3

491

Q6P9H4
RGHASRRPDRQAYEP

TRIP6

111

Q15654
CRRGHRQYLRSGPDY

REX1BD

81

Q96EN9
RRIHTGARPYECGQC

ZIK1

426

Q3SY52
DRPFRCGQCGRTYRH

ZNF646

1296

O15015
DERSHPPRYRGIGDC

SLC25A1

56

P53007
HSGERPYRCLRCGQR

ZNF517

311

Q6ZMY9
HSGERPYRCRACGRA

ZNF517

446

Q6ZMY9
NYRDHLRGRVRGPGS

UTS2R

321

Q9UKP6
LRADFQRHRRGGGCA

ZNF316

496

A6NFI3
RNHTGERPYECRECG

ZNF548

441

Q8NEK5
RIYRESRGRGSNEPH

SOX5

541

P35711
HEREGRPYCRRDFLQ

TGFB1I1

326

O43294
RECVRIYGGERPYTH

ZNF559

201

Q9BR84