Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncarbonate dehydratase activity

CA13 CA3 CA5A CA7

4.17e-06161424GO:0004089
GeneOntologyMolecularFunctionmedium-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

5.02e-0521422GO:0140981
GeneOntologyMolecularFunction16-hydroxypalmitate dehydrogenase activity

CYP4A11 CYP4A22

5.02e-0521422GO:0103002
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4A11 CYP27A1 CYP4A22

9.56e-05131423GO:0016713
GeneOntologyMolecularFunctionstructural constituent of synapse

ACTB ACTG1 RIMS1 RIMS2

2.22e-04421424GO:0098918
GeneOntologyMolecularFunctionglycosyltransferase activity

DPY19L3 ABO GALNT1 RPN2 TIPARP XYLT1 TMEM260 GYG2 UGT3A2

2.24e-042881429GO:0016757
GeneOntologyMolecularFunctionphosphoric ester hydrolase activity

PDE1B DUSP5 DUSP9 PON1 PTPRU PTPRT GDPD4 FIG4 SSH3 CA3

4.49e-0438614210GO:0042578
GeneOntologyMolecularFunctionfibroblast growth factor receptor activity

FGFR3 FGFR2

4.95e-0451422GO:0005007
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

PDE1B DUSP5 DUSP9 PON1 PTPRU PTPRT GDPD4 PPT1 FIG4 LIPM PXDNL SSH3 PGAP1 ALKBH3 CA3

6.39e-0480714215GO:0016788
GeneOntologyMolecularFunctionhexosyltransferase activity

DPY19L3 ABO GALNT1 RPN2 TMEM260 GYG2 UGT3A2

7.94e-042111427GO:0016758
GeneOntologyMolecularFunctionprotein tyrosine phosphatase activity

DUSP5 DUSP9 PTPRU PTPRT SSH3

8.49e-041031425GO:0004725
GeneOntologyMolecularFunctionfibroblast growth factor binding

FGFR3 FGFR2 KLB

9.09e-04271423GO:0017134
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4A11 CYP4A22

1.03e-0371422GO:0050051
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4A11 CYP4A22

1.03e-0371422GO:0018685
GeneOntologyMolecularFunctionhydro-lyase activity

CA13 CA3 CA5A CA7

1.05e-03631424GO:0016836
GeneOntologyMolecularFunctioniron ion binding

CYP4A11 FA2H CYP27A1 CYP4A22 TET1 ALKBH3

1.22e-031661426GO:0005506
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase inhibitor activity

WDR81 RUBCN

1.37e-0381422GO:0141039
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

RIMS1 RIMS2

1.37e-0381422GO:0098882
GeneOntologyMolecularFunctionribosome binding

RPN2 NOMO1 NOMO2 EIF2A NOMO3

1.68e-031201425GO:0043022
GeneOntologyMolecularFunctiontransition metal ion binding

ABO GALNT1 CYP4A11 DTX1 FA2H CYP27A1 CA13 CYP4A22 TRIM16 ABCC8 DTX4 TET1 ALKBH3 KDM2B ZMYM4 CA3 CA5A CA7

1.96e-03118914218GO:0046914
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4A11 CYP4A22

2.18e-03101422GO:0052869
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

2.18e-03101422GO:0120250
GeneOntologyMolecularFunctionMAP kinase tyrosine phosphatase activity

DUSP5 DUSP9

2.18e-03101422GO:0033550
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4A11 CYP4A22

2.18e-03101422GO:0102033
GeneOntologyCellularComponentendoplasmic reticulum membrane

LRRC8C DPY19L3 EMC1 GALNT1 RPN2 CYP4A11 FA2H PON1 WDR81 GRIN2C ATG2A ATP10D CYP4A22 NOMO1 TMEM260 NOMO2 PGAP1 TRPM8 UGT3A2 SCFD1 SYVN1 NOMO3 SEZ6L

2.02e-05129314223GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

LRRC8C DPY19L3 EMC1 GALNT1 RPN2 CYP4A11 FA2H PON1 WDR81 GRIN2C ATG2A ATP10D CYP4A22 NOMO1 TMEM260 NOMO2 PGAP1 TRPM8 UGT3A2 SCFD1 SYVN1 NOMO3 SEZ6L

2.18e-05129914223GO:0098827
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO1 NOMO2 NOMO3

2.50e-0591423GO:0160064
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

LRRC8C DPY19L3 EMC1 GALNT1 RPN2 CYP4A11 FA2H PON1 WDR81 GRIN2C ATG2A ATP10D CYP4A22 NOMO1 TMEM260 NOMO2 PGAP1 TRPM8 UGT3A2 SCFD1 SYVN1 NOMO3 SEZ6L

3.04e-05132714223GO:0042175
GeneOntologyCellularComponentpresynaptic cytoskeleton

ACTG1 RIMS1 RIMS2

1.06e-04141423GO:0099569
GeneOntologyCellularComponentER membrane insertion complex

NOMO1 NOMO2 NOMO3

1.06e-04141423GO:0072379
GeneOntologyCellularComponentKICSTOR complex

SZT2 KICS2

2.72e-0441422GO:0140007
GeneOntologyCellularComponentblood microparticle

ACTB PON1 ACTG1 C1R C3 EIF2A

4.57e-041441426GO:0072562
GeneOntologyCellularComponentpresynaptic active zone cytoplasmic component

OSBPL2 RIMS1 RIMS2

4.92e-04231423GO:0098831
GeneOntologyCellularComponentdense body

ACTB ACTG1

9.41e-0471422GO:0097433
GeneOntologyCellularComponentcell cortex

SPIRE2 ACTB AXIN1 OSBPL2 TCL1A RIMS1 FGFR2 RIMS2 IQGAP3

9.99e-043711429GO:0005938
GeneOntologyCellularComponentcytoskeleton of presynaptic active zone

RIMS1 RIMS2

1.25e-0381422GO:0048788
DomainCarbonic_anhydrase_a-class_CS

CA13 CA3 CA5A CA7

1.51e-06121424IPR018338
Domain-

GTF2IRD2B GTF2I GTF2IRD2

1.71e-06414233.90.1460.10
DomainDUF2012

NOMO1 NOMO2 NOMO3

1.71e-0641423PF09430
DomainDUF2012

NOMO1 NOMO2 NOMO3

1.71e-0641423IPR019008
DomainGTF2I

GTF2IRD2B GTF2I GTF2IRD2

1.71e-0641423PS51139
DomainGTF2I

GTF2IRD2B GTF2I GTF2IRD2

1.71e-0641423PF02946
DomainGTF2I

GTF2IRD2B GTF2I GTF2IRD2

1.71e-0641423IPR004212
DomainCarbonic_anhydrase_a-class

CA13 CA3 CA5A CA7

4.10e-06151424IPR023561
DomainALPHA_CA_1

CA13 CA3 CA5A CA7

4.10e-06151424PS00162
DomainCarb_anhydrase

CA13 CA3 CA5A CA7

7.06e-06171424PF00194
DomainCarb_anhydrase

CA13 CA3 CA5A CA7

7.06e-06171424SM01057
Domain-

CA13 CA3 CA5A CA7

7.06e-061714243.10.200.10
DomainALPHA_CA_2

CA13 CA3 CA5A CA7

7.06e-06171424PS51144
DomainCarbonic_anhydrase_a

CA13 CA3 CA5A CA7

7.06e-06171424IPR001148
DomainCarb-bd-like_fold

NOMO1 NOMO2 NOMO3

2.34e-0581423IPR013784
DomainWWE

DTX1 TIPARP DTX4

9.00e-05121423PF02825
DomainWWE-dom

DTX1 TIPARP DTX4

9.00e-05121423IPR004170
DomainWWE

DTX1 TIPARP DTX4

9.00e-05121423PS50918
DomainCarboxyPept_regulatory_dom

NOMO1 NOMO2 NOMO3

1.16e-04131423IPR014766
Domain-

NOMO1 NOMO2 NOMO3

1.16e-041314232.60.40.1120
DomainCarboxyPept-like_regulatory

NOMO1 NOMO2 NOMO3

2.71e-04171423IPR008969
DomainWWE

DTX1 DTX4

3.41e-0441422SM00678
DomainWWE-dom_subgr

DTX1 DTX4

3.41e-0441422IPR018123
DomainFGF_rcpt_fam

FGFR3 FGFR2

3.41e-0441422IPR016248
DomainTYR_PHOSPHATASE_1

DUSP5 DUSP9 PTPRU PTPRT SSH3

5.03e-04861425PS00383
DomainTYR_PHOSPHATASE_dom

DUSP5 DUSP9 PTPRU PTPRT SSH3

5.30e-04871425IPR000387
DomainTYR_PHOSPHATASE_2

DUSP5 DUSP9 PTPRU PTPRT SSH3

5.30e-04871425PS50056
Domain-

DUSP5 DUSP9 PTPRU PTPRT SSH3

6.85e-049214253.90.190.10
DomainQuinoprotein_ADH-like_supfam

EMC1 WDR6 WDR87 WDR17

7.02e-04531424IPR011047
DomainAlpha_kinase

TRPM6 EEF2K

8.44e-0461422PF02816
DomainMHCK_EF2_kinase

TRPM6 EEF2K

8.44e-0461422IPR004166
DomainALPHA_KINASE

TRPM6 EEF2K

8.44e-0461422PS51158
DomainAlpha_kinase

TRPM6 EEF2K

8.44e-0461422SM00811
DomainProt-tyrosine_phosphatase-like

DUSP5 DUSP9 PTPRU PTPRT SSH3

9.55e-04991425IPR029021
Domainfn3

CHL1 BOC OBSCN PTPRU PTPRT USH2A

1.51e-031621426PF00041
DomainACTINS_1

ACTB ACTG1

1.56e-0381422PS00406
DomainDUSP

DUSP5 DUSP9 SSH3

1.65e-03311423IPR024950
DomainTYR_PHOSPHATASE_DUAL

DUSP5 DUSP9 SSH3

2.17e-03341423PS50054
DomainTyr_Pase_AS

DUSP5 PTPRU PTPRT SSH3

2.32e-03731424IPR016130
DomainDSPc

DUSP5 DUSP9 SSH3

2.36e-03351423SM00195
DomainTYR_PHOSPHATASE_DUAL_dom

DUSP5 DUSP9 SSH3

2.36e-03351423IPR020422
DomainMKP

DUSP5 DUSP9

2.48e-03101422IPR008343
DomainIg-like_fold

CHL1 BOC OBSCN PTPRU PTPRT NOMO1 NOMO2 PXDNL FGFR3 FGFR2 SEMA4A USH2A NOMO3

2.87e-0370614213IPR013783
DomainFN3

CHL1 BOC OBSCN PTPRU PTPRT USH2A

2.93e-031851426SM00060
DomainZF_CXXC

TET1 KDM2B

3.02e-03111422PS51058
DomainFYVE_2

RIMS1 RIMS2

3.02e-03111422PF02318
DomainZnf_CXXC

TET1 KDM2B

3.02e-03111422IPR002857
Domainzf-CXXC

TET1 KDM2B

3.02e-03111422PF02008
DomainIg_I-set

CHL1 BOC OBSCN PXDNL FGFR3 FGFR2

3.34e-031901426IPR013098
DomainI-set

CHL1 BOC OBSCN PXDNL FGFR3 FGFR2

3.34e-031901426PF07679
DomainRABBD

RIMS1 RIMS2

3.60e-03121422PS50916
DomainRab_BD

RIMS1 RIMS2

3.60e-03121422IPR010911
DomainDual-sp_phosphatase_cat-dom

DUSP5 DUSP9 SSH3

3.71e-03411423IPR000340
DomainDSPc

DUSP5 DUSP9 SSH3

3.71e-03411423PF00782
Domain-

WDR81 WDR26 TBC1D31 WDR6 WDR87 SEMA4A EIF2A WDR17

4.00e-0333314282.130.10.10
DomainWD40/YVTN_repeat-like_dom

WDR81 WDR26 TBC1D31 WDR6 WDR87 SEMA4A EIF2A WDR17

4.14e-033351428IPR015943
DomainFN3

CHL1 BOC OBSCN PTPRU PTPRT USH2A

4.19e-031991426PS50853
Domain-

CHL1 BOC OBSCN PTPRU PTPRT NOMO1 NOMO2 PXDNL FGFR3 FGFR2 USH2A NOMO3

4.74e-03663142122.60.40.10
DomainCyt_P450_E_grp-I

CYP4A11 CYP27A1 CYP4A22

4.83e-03451423IPR002401
DomainFN3_dom

CHL1 BOC OBSCN PTPRU PTPRT USH2A

5.31e-032091426IPR003961
DomainWD_REPEATS_1

WDR81 WDR26 TBC1D31 WDR6 WDR87 EIF2A WDR17

5.43e-032781427PS00678
DomainWD_REPEATS_2

WDR81 WDR26 TBC1D31 WDR6 WDR87 EIF2A WDR17

5.53e-032791427PS50082
DomainWD_REPEATS_REGION

WDR81 WDR26 TBC1D31 WDR6 WDR87 EIF2A WDR17

5.53e-032791427PS50294
DomainCUB

PAMR1 C1R SEZ6L

6.14e-03491423PF00431
DomainMAM_1

PTPRU PTPRT

6.42e-03161422PS00740
DomainActin_CS

ACTB ACTG1

6.42e-03161422IPR004001
DomainCUB

PAMR1 C1R SEZ6L

6.50e-03501423SM00042
DomainMAM

PTPRU PTPRT

7.24e-03171422SM00137
DomainACTINS_2

ACTB ACTG1

7.24e-03171422PS00432
Domain-

PAMR1 C1R SEZ6L

7.24e-035214232.60.120.290
DomainSushi

PAMR1 C1R SEZ6L

7.24e-03521423PF00084
PathwayREACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE

CA13 CA3 CA5A CA7

1.08e-0612994M671
PathwayREACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE

CA13 CA3 CA5A CA7

1.08e-0612994MM14574
PathwayKEGG_NITROGEN_METABOLISM

CA13 CA3 CA5A CA7

1.83e-0523994M4629
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO1 NOMO2 NOMO3

7.10e-083145336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO1 NOMO2 NOMO3

7.10e-083145325576386
Pubmed

A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system.

CA13 CA3 CA5A CA7

1.40e-0712145417362527
Pubmed

Evolution of general transcription factors.

GTF2IRD2B GTF2I GTF2IRD2

2.83e-074145323229069
Pubmed

GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.

GTF2IRD2B GTF2I GTF2IRD2

2.83e-074145322899722
Pubmed

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

GTF2IRD2B GTF2I GTF2IRD2

2.83e-074145317823943
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO1 NOMO2 NOMO3

2.83e-074145331833031
Pubmed

Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.

GTF2IRD2B GTF2I GTF2IRD2

2.83e-074145321328569
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO1 NOMO2 NOMO3

2.83e-07414539267806
Pubmed

FGF21 signalling pathway and metabolic traits - genetic association analysis.

FGFR3 FGFR2 KLB

7.05e-075145320717167
Pubmed

Microtubule associated protein MAP1A is an actin-binding and crosslinking protein.

MAP1A ACTB ACTG1

7.05e-07514537820861
Pubmed

A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development.

CA13 CA3 CA5A CA7

2.00e-0622145423233153
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

TRPM6 RPN2 ACTB NUP88 ACTG1 ZNF658B NSUN2 GTF2I SSH3 SDHA KLB

3.29e-064511451136168627
Pubmed

betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.

FGFR3 FGFR2 KLB

3.91e-068145318187602
Pubmed

Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21.

FGFR3 FGFR2 KLB

3.91e-068145317623664
Pubmed

Carbonic anhydrases in the mouse harderian gland.

CA13 CA3 CA7

3.91e-068145320820888
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO1 NOMO2 NOMO3

3.91e-068145315257293
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO1 NOMO2 NOMO3

5.85e-069145336261522
Pubmed

Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.

EMC1 NOMO1 NOMO2 SYVN1 NOMO3

6.80e-0663145531266804
Pubmed

Hepatic lipase maturation: a partial proteome of interacting factors.

ACTB NOMO1 NOMO2 NOMO3

8.36e-0631145419136429
Pubmed

An analysis of expression patterns of genes encoding proteins with catalytic activities.

CA13 SDHA CA3 CA5A CA7

9.22e-0667145517626619
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZSCAN4 USP24 NUP88 WDR26 GTF2I WDR6 TET1 KDM2B CAMSAP1 ZMYM4

1.10e-054181451034709266
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTB ACTG1 SLIT2

1.14e-0511145323294842
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO1 NOMO2 NOMO3

1.14e-0511145332820719
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

EMC1 RPN2 DUSP5 DUSP9 NUP88 PTPRU WDR26 NOMO1 GTF2I WDR6 PREP C3 EIF2A SDHA XPR1

1.48e-059741451528675297
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

BOC GRB14 PTPRU SLIT2 FGFR3 FGFR2

1.55e-05126145616284245
Pubmed

Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.

ACTB ACTG1

1.73e-052145221778137
Pubmed

Normal immune system development in mice lacking the Deltex-1 RING finger domain.

DTX1 DTX4

1.73e-052145215684394
Pubmed

Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension.

CYP4A11 CYP4A22

1.73e-052145215611369
Pubmed

De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.

ACTB ACTG1

1.73e-052145222366783
Pubmed

Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.

ACTB ACTG1

1.73e-052145232588558
Pubmed

Baraitser-Winter cerebrofrontofacial syndrome.

ACTB ACTG1

1.73e-052145227625340
Pubmed

Activation of FGF receptors by mutations in the transmembrane domain.

FGFR3 FGFR2

1.73e-05214529136983
Pubmed

Prognostic impact of FGFR2/3 alterations in patients with biliary tract cancers receiving systemic chemotherapy: the BITCOIN study.

FGFR3 FGFR2

1.73e-052145235303508
Pubmed

RIM2α is a molecular scaffold for Zona pellucida-induced acrosome reaction.

RIMS1 RIMS2

1.73e-052145225240052
Pubmed

Androgen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.

CYP4A11 CYP4A22

1.73e-052145223641057
Pubmed

The Blood Pressure-Lowering Effect of 20-HETE Blockade in Cyp4a14(-/-) Mice Is Associated with Natriuresis.

CYP4A11 CYP4A22

1.73e-052145228912346
Pubmed

Altered inflammatory responses to Citrobacter rodentium infection, but not bacterial lipopolysaccharide, in mice lacking the Cyp4a10 or Cyp4a14 genes.

CYP4A11 CYP4A22

1.73e-052145224413902
Pubmed

Rapidly acquired resistance to EGFR tyrosine kinase inhibitors in NSCLC cell lines through de-repression of FGFR2 and FGFR3 expression.

FGFR3 FGFR2

1.73e-052145221152424
Pubmed

Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.

ACTB ACTG1

1.73e-05214523221869
Pubmed

ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR.

ACTB SDHA

1.73e-052145230259794
Pubmed

Deduced amino acid sequence of a murine cytochrome P-450 Cyp4a protein: developmental and hormonal regulation in liver and kidney.

CYP4A11 CYP4A22

1.73e-05214528031839
Pubmed

Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein.

CYP4A11 CYP4A22

1.73e-052145210860550
Pubmed

Analysis of RIM Expression and Function at Mouse Photoreceptor Ribbon Synapses.

RIMS1 RIMS2

1.73e-052145228701482
Pubmed

TET1 suppresses colon cancer proliferation by impairing β-catenin signal pathway.

AXIN1 TET1

1.73e-052145230825236
Pubmed

Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension.

CYP4A11 CYP4A22

1.73e-052145211320253
Pubmed

Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.

ACTB ACTG1

1.73e-052145221502360
Pubmed

Germline mutations in FGF receptors and medulloblastomas.

FGFR3 FGFR2

1.73e-052145223325524
Pubmed

The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.

ACTB ACTG1

1.73e-05214526686106
Pubmed

RIM C2B Domains Target Presynaptic Active Zone Functions to PIP2-Containing Membranes.

RIMS1 RIMS2

1.73e-052145229606581
Pubmed

Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.

ACTB ACTG1

1.73e-0521452213279
Pubmed

The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.

ACTB ACTG1

1.73e-052145233334799
Pubmed

Characterization of the CYP4A11 gene, a second CYP4A gene in humans.

CYP4A11 CYP4A22

1.73e-052145212464262
Pubmed

β-Actin specifically controls cell growth, migration, and the G-actin pool.

ACTB ACTG1

1.73e-052145221900491
Pubmed

RIM1/2-Mediated Facilitation of Cav1.4 Channel Opening Is Required for Ca2+-Stimulated Release in Mouse Rod Photoreceptors.

RIMS1 RIMS2

1.73e-052145226400943
Pubmed

Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma.

FGFR3 FGFR2

1.73e-052145223786770
Pubmed

Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.

CYP4A11 CYP4A22

1.73e-052145215066132
Pubmed

Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.

ACTB ACTG1

1.73e-052145219638415
Pubmed

Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.

ACTB ACTG1

1.73e-05214523335520
Pubmed

Fibroblast growth factor receptor 3 is a negative regulator of bone growth.

FGFR3 FGFR2

1.73e-05214528601314
Pubmed

Association of human immunodeficiency virus Nef protein with actin is myristoylation dependent and influences its subcellular localization.

ACTB ACTG1

1.73e-05214529288906
Pubmed

WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway.

WDR26 AXIN1

1.73e-052145227098453
Pubmed

High level expression of transfected beta- and gamma-actin genes differentially impacts on myoblast cytoarchitecture.

ACTB ACTG1

1.73e-05214521577857
Pubmed

A presynaptic phosphosignaling hub for lasting homeostatic plasticity.

RIMS1 RIMS2

1.73e-052145235443170
Pubmed

20-HETE induces remodeling of renal resistance arteries independent of blood pressure elevation in hypertension.

CYP4A11 CYP4A22

1.73e-052145223825080
Pubmed

Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel.

CYP4A11 CYP4A22

1.73e-052145216691295
Pubmed

The P450 gene superfamily: recommended nomenclature.

CYP4A11 CYP4A22

1.73e-05214523829886
Pubmed

Novel targetable FGFR2 and FGFR3 alterations in glioblastoma associate with aggressive phenotype and distinct gene expression programs.

FGFR3 FGFR2

1.73e-052145233853673
Pubmed

Baraitser-Winter Cerebrofrontofacial Syndrome

ACTB ACTG1

1.73e-052145226583190
Pubmed

Knockout of ACTB and ACTG1 with CRISPR/Cas9(D10A) Technique Shows that Non-Muscle β and γ Actin Are Not Equal in Relation to Human Melanoma Cells' Motility and Focal Adhesion Formation.

ACTB ACTG1

1.73e-052145232326615
Pubmed

Induction of cytochrome P450 4A14 contributes to angiotensin II-induced renal fibrosis in mice.

CYP4A11 CYP4A22

1.73e-052145229277328
Pubmed

Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.

CYP4A11 CYP4A22

1.73e-052145221820496
Pubmed

Severe forms of Baraitser-Winter syndrome are caused by ACTB mutations rather than ACTG1 mutations.

ACTB ACTG1

1.73e-052145223756437
Pubmed

Early mandibular morphological differences in patients with FGFR2 and FGFR3-related syndromic craniosynostoses: A 3D comparative study.

FGFR3 FGFR2

1.73e-052145232822871
Pubmed

Renal function and vasomotor activity in mice lacking the Cyp4a14 gene.

CYP4A11 CYP4A22

1.73e-052145220943934
Pubmed

Cytochalasin D-induced actin gene expression in murine erythroleukemia cells.

ACTB ACTG1

1.73e-05214528482333
Pubmed

The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes.

CYP4A11 CYP4A22

1.73e-05214522766933
Pubmed

Impaired muscle relaxation and mitochondrial fission associated with genetic ablation of cytoplasmic actin isoforms.

ACTB ACTG1

1.73e-052145229265728
Pubmed

Multi-isotope imaging mass spectrometry reveals slow protein turnover in hair-cell stereocilia.

ACTB ACTG1

1.73e-052145222246323
Pubmed

RIM genes differentially contribute to organizing presynaptic release sites.

RIMS1 RIMS2

1.73e-052145222753485
Pubmed

Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes.

ACTB ACTG1

1.73e-05214522837653
Pubmed

Prevalence of Cytoplasmic Actin Mutations in Diffuse Large B-Cell Lymphoma and Multiple Myeloma: A Functional Assessment Based on Actin Three-Dimensional Structures.

ACTB ACTG1

1.73e-052145232349449
Pubmed

Baraitser-Winter cerebrofrontofacial syndrome: Report of two adult siblings.

ACTB ACTG1

1.73e-052145232506774
Pubmed

Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.

FGFR3 FGFR2

1.73e-052145211325814
Pubmed

Differential arginylation of actin isoforms is regulated by coding sequence-dependent degradation.

ACTB ACTG1

1.73e-052145220847274
Pubmed

Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.

CYP4A11 CYP4A22

1.73e-052145217112342
Pubmed

Comparison of TFII-I gene family members deleted in Williams-Beuren syndrome.

GTF2IRD2B GTF2IRD2

1.73e-052145215388857
Pubmed

High-fat diet-induced obesity and insulin resistance in CYP4a14-/- mice is mediated by 20-HETE.

CYP4A11 CYP4A22

1.73e-052145230088983
Pubmed

The presynaptic active zone protein RIM1α controls epileptogenesis following status epilepticus.

RIMS1 RIMS2

1.73e-052145222956829
Pubmed

Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases.

CYP4A11 CYP4A22

1.73e-052145219208908
Pubmed

An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.

ACTB FGFR3 FGFR2

3.11e-0515145327046834
Pubmed

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.

ACTB PON1 ACTG1 C1R C3 EIF2A

3.16e-05143145622516433
Pubmed

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

NOMO1 DOK4 NOMO2 NOMO3 CA7

4.32e-0592145510493829
Pubmed

The cleavage of host cell proteins by HIV-1 protease.

MAP1A ACTB ACTG1

4.62e-051714538997639
Pubmed

Transient Redirection of SVZ Stem Cells to Oligodendrogenesis by FGFR3 Activation Promotes Remyelination.

FGFR3 FGFR2

5.16e-053145231189094
Pubmed

Molecular characterization of abLIM, a novel actin-binding and double zinc finger protein.

ACTB ACTG1

5.16e-05314529245787
Pubmed

Genetic analysis of resistance to radiation lymphomagenesis with recombinant inbred strains of mice.

CYP4A11 CYP4A22

5.16e-05314522354437
Pubmed

Impact of altered actin gene expression on vinculin, talin, cell spreading, and motility.

ACTB ACTG1

5.16e-05314527646816
Pubmed

Isolation of the complementary DNA encoding a mouse heparin-binding growth factor receptor with the use of a unique kinase insert sequence.

FGFR3 FGFR2

5.16e-05314528382556
Pubmed

Angiostatin and plasminogen share binding to endothelial cell surface actin.

ACTB ACTG1

5.16e-053145215746964
GeneFamilyCarbonic anhydrases

CA13 CA3 CA5A CA7

2.44e-0618994460
GeneFamilyRegulating synaptic membrane exocytosis family|PDZ domain containing

RIMS1 RIMS2

1.77e-044992833
GeneFamilyFibronectin type III domain containing

CHL1 BOC OBSCN PTPRU PTPRT USH2A

2.49e-04160996555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 BOC OBSCN PXDNL FGFR3 FGFR2

2.57e-04161996593
GeneFamilyActins

ACTB ACTG1

4.39e-046992929
GeneFamilyMAP kinase phosphatases

DUSP5 DUSP9

1.58e-0311992895
GeneFamilyZinc fingers CXXC-type

TET1 KDM2B

1.89e-0312992136
GeneFamilyWD repeat domain containing

WDR81 WDR26 TBC1D31 WDR6 WDR87 WDR17

3.19e-03262996362
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

WDR81 AXIN1 YLPM1 SPRED1 PPP1R36

3.19e-03181995694
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAMR1 C1R SEZ6L

3.76e-03579931179
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRU PTPRT

5.82e-0321992813
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DUSP9 OBSCN EPB41L4A PTPRT SYT8 FGFR3 FGFR2 XPR1

2.59e-0719514586c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CHL1 DPY19L3 DCK ARMC2 ZNF23 SPRED1 MAST3

1.82e-061761457792f414f5092aba14260b8e16378e793a822498e
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

CHL1 CCDC60 EPB41L4A SYT8 FGFR3 FGFR2 XPR1

2.36e-06183145700a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellfacs-Skin-Anagen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 GALNT1 RPN2 CA13 NSUN2 LIPM PREP

2.63e-0618614579a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 TRPM6 OBSCN ACTG1 PTPRT PGAP1 FGFR3

3.97e-0619814575374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GALNT1 PAMR1 CA13 NEB SLIT2 SYVN1

1.94e-05169145616c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

BOC PDE1B MAP1A C16orf89 SLIT2 WDR17

1.94e-051691456e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PAMR1 PTPRU C16orf89 C1R C3

2.36e-051751456b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PAMR1 PTPRU C16orf89 C1R C3

2.36e-0517514567ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PDE1B OBSCN ATP10D SLIT2 C1R

2.52e-051771456bd602db857f37869ef76d14c05ef522c509f08ee
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHL1 PTPRU EPB41L4A FGFR3 FGFR2 XPR1

2.52e-051771456cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CHL1 PTPRU EPB41L4A FGFR3 FGFR2 XPR1

2.52e-051771456ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellCOVID-19_Convalescent-PLT_1|World / Disease Group and Platelet Clusters

EMC1 NOMO2 YLPM1 GTF2IRD2 CRYZL1 SYVN1

2.68e-051791456d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

MAN1A1 DUSP5 ACTB RUBCN SEZ6L CA5A

2.77e-051801456aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PAMR1 C16orf89 SLIT2 C1R C3

2.85e-051811456e1ae9ada60ec89e7a7cde9c231c1a099ed2ffecc
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Thalamus / BrainAtlas - Mouse McCarroll V32

RAB19 TLR6 C16orf89 GVINP1 CA5A

2.89e-0510914554e4a884b8979f4ff8b232c1581ea78884dda29ed
ToppCellfacs-Skin-Telogen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 GALNT1 TRIM16 DOK4 LIPM EEF2K

3.04e-051831456ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCellmetastatic_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|metastatic_Lymph_Node / Location, Cell class and cell subclass

DTX1 ACTB ACTG1 TCL1A SEMA4A SYVN1

3.04e-05183145630db83f600e2c4ad3af68a8a946673f4352a2807
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

TRPM6 EPB41L4A SYT8 FGFR3 FGFR2 XPR1

3.43e-0518714568407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

NSUN2 AXIN1 ARL5B TBC1D31 POLR3E TET1

3.53e-0518814568f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

CHL1 GRB14 TIPARP NOMO1 NOMO2 NOMO3

3.86e-051911456ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellIPF-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

CHL1 DUSP5 C16orf89 C3 RIMS1 FGFR2

3.86e-051911456267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC HIC1 TIPARP C16orf89 C1R C3

3.97e-0519214569479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

MAN1A1 PAMR1 XYLT1 SLIT2 C1R C3

3.97e-051921456356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellfacs-Skin-Anagen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 RPN2 NSUN2 TIPARP PREP FGFR2

3.97e-051921456ec1fd2fb6e71f87189d66261909a84e2be63cacb
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC HIC1 TIPARP C16orf89 C1R C3

3.97e-051921456d7faa993f68e530ad55185505384ae155d36c222
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

CHL1 FA2H PTPRU C16orf89 RIMS1 FGFR2

3.97e-05192145693b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCell11.5-Airway-Mesenchymal-Cartilage|Airway / Age, Tissue, Lineage and Cell class

BOC DUSP9 XYLT1 SYT8 FGFR3 FGFR2

4.09e-051931456d4779d92a4dd4b8b656383e6f4fce76d3bd70931
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPN2 ACTB ACTG1 NEB WDR6 ABCC8

4.21e-0519414563a3ecedcdc7691cf21775818b598208fcb980c29
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHL1 DTX4 C3 FGFR3 RIMS1 FGFR2

4.21e-0519414562172d951896265243d14996eacce5aab5e14e26e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 MAN1A1 DUSP9 USP24 GRB14 GTF2I

4.33e-051951456a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellHealthy-B_intermediate|World / disease group, cell group and cell class

CHL1 BOC DTX1 NEB PTPRT TCL1A

4.33e-0519514569de79e0bdd9063ae65e5edb89cc3fe6f9a8173bc
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

DPY19L3 POLR3E GTF2IRD2 TRPM8 FGFR3 SEMA4A

4.45e-0519614567be50b9156394dea44d7b8b476d4dd516abfafae
ToppCelldistal-mesenchymal-Lipofibroblast-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BOC PAMR1 SLIT2 PGAP1 C1R C3

4.58e-051971456865010edcd7e3f79f505fcef7b33882095994aa8
ToppCelldistal-mesenchymal-Lipofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BOC PAMR1 SLIT2 PGAP1 C1R C3

4.58e-051971456ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EPB41L4A PTPRT SYT8 FGFR3 FGFR2 XPR1

4.58e-051971456107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCellCOVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast|COVID_vent / Disease condition, Lineage, Cell class and subclass

MAN1A1 RPN2 NOMO1 NOMO2 SYVN1 NOMO3

4.58e-05197145699fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHL1 DTX4 C3 FGFR3 RIMS1 FGFR2

4.58e-051971456a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell367C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BOC CYP27A1 TIPARP C16orf89 C1R C3

4.85e-0519914562aed8f4a225a3762a5e7ce99aacad9b2a37d61f1
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 TRPM6 OBSCN PTPRT PGAP1 FGFR3

4.85e-05199145694a7867e800df352731796de8c24cba133c29622
ToppCell367C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

BOC CYP27A1 TIPARP C16orf89 C1R C3

4.85e-051991456c40ca26345753a2197bd9389d7323f7491c1e11d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 USP24 PTPRT XYLT1 ABCC8 SEZ6L

4.85e-051991456333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHL1 DTX4 C3 FGFR3 RIMS1 FGFR2

4.85e-05199145632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 USP24 PTPRT XYLT1 ABCC8 SEZ6L

4.85e-05199145619a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 USP24 PTPRT XYLT1 ABCC8 SEZ6L

4.85e-051991456e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHL1 DTX4 C3 FGFR3 RIMS1 FGFR2

4.85e-051991456262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCelldistal-1-mesenchymal-Lipofibroblast|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

BOC PAMR1 SLIT2 PGAP1 C1R C3

4.85e-051991456a8293db3c42a8d30897858b49aae7acfc18663ba
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Mesenchymal|GW08 / Sample Type, Dataset, Time_group, and Cell type.

BOC LRRC8C CA13 DNAJC22 SYVN1 MAST3

4.98e-052001456e5b7d9622b96bb20c81ac76b4e60e8b44fa9cca1
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CA13 PTPRU LIPM IQGAP3 CA3

7.76e-0513414554ef5f395e321cf04e56560be2502a8aa157682f4
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MAN1A1 RPN2 NOMO1 NOMO2 SEMA4A

1.13e-041451455fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--|Thalamus / BrainAtlas - Mouse McCarroll V32

RAB19 TLR6 GVINP1 CA5A

1.17e-047714549743d4a79c8694f76ab780b9e52b4c6ac1af33ed
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-|Thalamus / BrainAtlas - Mouse McCarroll V32

RAB19 TLR6 GVINP1 CA5A

1.17e-0477145422e8c486ad82773b1facd8dd55ed3f448612c600
ToppCellThalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)|Thalamus / BrainAtlas - Mouse McCarroll V32

RAB19 TLR6 GVINP1 CA5A

1.17e-047714547e30a46aa68a9374c4c99385a383e0865ff45b1c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO1 C16orf89 SPRED1 RIMS2 NOMO3

1.45e-0415314554eb9c2d7e4b95d44198fc87dc115a08ef0153e26
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO1 C16orf89 SPRED1 RIMS2 NOMO3

1.45e-04153145526b5b45c117d155b028d298a0b93e16d343dca97
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NOMO1 C16orf89 SPRED1 RIMS2 NOMO3

1.45e-0415314550f12e38f2cbf69a520764289b0aa4dedc645f714
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPY19L3 DTX1 GRIN2C ABCC8 FGFR3

1.49e-0415414555ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TRPM6 EPB41L4A SYT8 WDR87 FGFR2

1.63e-0415714556ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHL1 DUSP5 C3 RIMS1 FGFR2

1.73e-04159145560b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellLAM-Lymphoid-pDC|LAM / Condition, Lineage and Cell class

MAP1A DUSP5 DCK TCL1A RUBCN

1.83e-041611455bb5b44713e4da4406cdaa79dcf2aa9f97e3cf75a
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DPY19L3 DUSP5 OBSCN ABCC8 CA7

1.94e-041631455218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCellClub-club-12|World / Class top

PON1 C16orf89 ABCC8 C3 CA5A

2.06e-0416514559b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAMR1 FA2H SYT8 C3

2.23e-04911454b0658e020f80e56fab9d2aa07e321d9b33d7af2c
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ACTB ACTG1 TCL1A SEMA4A SYVN1

2.24e-04168145508eb1284f9b8bd3e0e4b21bfc2bbee01d35a0bd7
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAM7 ACTB RAB39B USH2A

2.42e-0493145493a8d3ad978e4cd450f7a69a4cbac1a59038e80d
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRU LIPM ABCC8 C3 IQGAP3

2.43e-041711455913bae728b5e653771a27c79a309eb023699f1d0
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

CHL1 TRPM6 EPB41L4A FGFR3 FGFR2

2.43e-0417114553965ced4be6db14265a90673502fceee425837ca
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRU LIPM ABCC8 C3 IQGAP3

2.43e-041711455f28b2336057e353b96a6ff4581ec9fd0ca0789d9
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FA2H CA13 SYT8 RAB39B CA3

2.43e-0417114558ed98f223143bd81d9819e9a420eb9cc81ee6c53
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FA2H CA13 SYT8 RAB39B CA3

2.43e-041711455bd339e482f09a3fa04b086029b94f45205b8a6c5
ToppCell3'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPB41L4A ARL5B PPP1R36 CA5A CA7

2.43e-041711455317b70d72a4ca5336cfb6a49dc57f8e2a8a1c736
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CHL1 C16orf89 C3 FGFR3 RIMS1

2.56e-041731455d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

CHL1 EPB41L4A SYT8 WDR87 XPR1

2.63e-041741455a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

TRPM8 FGFR3 FGFR2 SEMA4A IQGAP3

2.63e-041741455fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellASK452-Immune-B_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC60 DUSP5 CA13 PTPRU TCL1A

2.63e-04174145569723f5666abc3af5f0431901a60246c9915ef81
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC PAMR1 TIPARP C1R C3

2.63e-0417414559c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellTCGA-Liver|World / Sample_Type by Project: Shred V9

CYP4A11 PON1 CYP4A22 CA5A KLB

2.63e-041741455452932f08cf53e5949672a025d78cecb874aa4b0
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC PAMR1 TIPARP C1R C3

2.63e-041741455bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABO FA2H PREP CA3 CA7

2.70e-0417514558727252bcbc70bfa2ff72e7421df9cfe6fd4eed7
ToppCellTCGA-Colorectal-Recurrent_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP4A11 PON1 CYP4A22 TRPM8 CA5A

2.70e-0417514557f74961436f88c0e380819095e6104489914d765
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABO TEX15 PTPRU NPFFR2 SEMA4A

2.70e-04175145590e29945aa861082c94bb4f331161adc3a6ef899
ToppCellCOVID-19_Convalescent|World / Disease Group and Platelet Clusters

LRRC8C EMC1 NOMO2 GTF2IRD2 SECISBP2

2.70e-041751455e9b1faa4c85537f30306619a2f3ada6c8ef0ac6c
ToppCellTCGA-Colorectal-Recurrent_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP4A11 PON1 CYP4A22 TRPM8 CA5A

2.70e-041751455bee8f31f036dfcf9fc6ed29156554771a9ee3c60
ToppCell(03)_Secretory-(4)_1wkpi|(03)_Secretory / shred by cell type and Timepoint

MAN1A1 GALNT1 PON1 EEF2K FGFR3

2.70e-04175145506b52f85baa31b55bb31477244892b6da79fe2c9
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABO FA2H PREP CA3 CA7

2.70e-041751455c083abe368e5c0dc2b0f27f375c9271a2d7ff64f
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CA13 GYG2 CA3 CA5A KLB

2.77e-0417614551e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABO TEX15 PTPRU NPFFR2 SEMA4A

2.77e-041761455e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZNF23 TBC1D31 ABCC8 RAB39B SEZ6L

2.84e-0417714558abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|343B / Donor, Lineage, Cell class and subclass (all cells)

HIC1 CNBD2 EPB41L4A TBC1D31 POLR3E

2.92e-0417814555289ac61637224ae70ffbc2d164d73116f10af40
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE1B MAP1A TLR6 ARMC2 CA3

3.00e-041791455b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellASK452-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC60 DUSP5 CA13 PTPRU TCL1A

3.00e-041791455c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

TRPM6 EPB41L4A SYT8 FGFR2 XPR1

3.00e-041791455d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellNS-moderate-d_16-33-Myeloid-pDC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A DUSP5 DCK TCL1A RUBCN

3.07e-041801455144818e69613296cde43f29cb8c20899c670b319
ToppCellControl-Epithelial-Goblet|Control / Disease state, Lineage and Cell class

CHL1 C16orf89 FGFR3 RIMS1 FGFR2

3.07e-0418014555293d23b8b8ea587239ffde561b70bad01632521
ToppCellmoderate-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A DUSP5 DCK TCL1A RUBCN

3.07e-0418014551d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCelldroplet-Lung-LUNG-1m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PON1 GRB14 TEX15 ZNF23 FGFR2

3.23e-041821455c1e0be27064e14043b78ae501b02d4e9542267a3
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod|TCGA-Mesothelium / Sample_Type by Project: Shred V9

TRAF3IP2 DOK4 SSH3 C1R C3

3.23e-041821455bb1f815718397de96682697fcbd6014a992a28f7
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PON1 GRB14 TEX15 ZNF23 FGFR2

3.23e-0418214553c9b4869d357884ae4bcd22a9872faf83a5cfc6d
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 CA13 TIPARP TRIM16 LIPM

3.31e-04183145526b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHL1 BOC DTX1 NEB PTPRT

3.31e-04183145501664fce6b70a02c9d39d747b6a6aabc86d57bc2
DrugFg 400

BOC CA13 CA3 CA5A CA7

1.17e-08131445CID000012443
Drugmetolazone

CA13 SLC6A7 CA3 CA5A CA7

5.49e-08171445CID000004170
Drugaminozolamide

CA13 CA3 CA5A CA7

1.05e-0781444CID000093505
DrugL-662,583

CA13 CA3 CA5A CA7

1.05e-0781444CID003082977
DrugL-643,799

CA13 CA3 CA5A CA7

1.05e-0781444CID000121595
Drugsezolamide

CA13 CA3 CA5A CA7

1.05e-0781444CID000060692
Drugqassa

CA13 CA3 CA5A CA7

1.89e-0791444CID003082191
Drug6-hydroxyethoxzolamide

CA13 CA3 CA5A CA7

1.89e-0791444CID000094706
DrugProntosil

CA13 CA3 CA5A CA7

3.13e-07101444CID000066895
Drugmetanilamide

CA13 CA3 CA5A CA7

3.13e-07101444CID000007377
Drug1,3-benzenedisulfonamide

CA13 CA3 CA5A CA7

3.13e-07101444CID003090044
DrugCl 13850

CA13 CA3 CA5A CA7

4.89e-07111444CID000159459
Drugcobalt phosphate

CA13 CA3 CA5A CA7

4.89e-07111444CID000061615
DrugTio-urasin

CA13 CA3 CA5A CA7

4.89e-07111444CID000084724
Drughydroflumethiazide

CA13 CA3 CA5A CA7

7.30e-07121444CID000003647
Drugmafenide acetate

CA13 CA3 CA5A CA7

1.05e-06131444CID000003998
Drugchlorzolamide

CA13 CA3 CA5A CA7

1.05e-06131444CID000165323
Drugsulfamide

BOC CA13 CA3 CA5A CA7

1.40e-06311445CID000082267
Drugcobalt;sulfide

CA13 CA3 CA5A CA7

1.46e-06141444CID000159453
Drugapraclonidine

CA13 CA3 CA5A CA7

4.38e-06181444CID000002216
Drugorthanilamide

CA13 CA5A CA7

4.89e-0661443CID000072894
DrugMethapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; MCF7; HT_HG-U133A

ADAM7 DUSP9 PTPRU NEB ATP10D DOK4 EFR3B GYG2 MAST3

5.11e-0619914493205_UP
Drugsulthiame

CA13 CA3 CA5A CA7

5.52e-06191444CID000005356
DrugAC1LCVB4

CA13 CA3 CA5A CA7

8.45e-06211444CID000656627
DrugAABSSN

CA13 CA3 CA5A CA7

1.03e-05221444CID005464134
Drugdichlorphenamide

CA13 CA3 CA5A CA7

1.24e-05231444CID000003038
Drug1,3-dibromopropane

BOC LIPM C3

1.36e-0581443CID000008001
Drugp-nitrophenyl acetate

PON1 CA13 POLR3E CA3 CA5A CA7

1.46e-05831446CID000013243
Drugpotassium cyanate

CA13 CA3 CA5A CA7

1.48e-05241444CID011378442
Drugmethazolamide

CA13 CA3 CA5A CA7

2.06e-05261444CID000004100
DrugN-methyl-1(R)-aminoindan

TRAF3IP2 KIFBP TIPARP NOMO1 GTF2IRD2B GTF2I GTF2IRD2

2.13e-051321447CID005494442
Drugsulfonamide

CA13 KRIT1 CA3 CA5A CA7

2.33e-05541445CID000005333
DrugCapobenic acid

BOC CYP27A1 YLPM1 C3

2.41e-05271444CID000030627
Drugimidazole

BOC PDE1B CYP4A11 FA2H CA13 C3 CA3 CA5A CA7

2.44e-052421449CID000000795
Drug1gaf

CA13 PTPRU CA3 CA5A CA7

2.78e-05561445CID000444283
Drugbenzolamide

CA13 CA3 CA5A CA7

2.79e-05281444CID000018794
Drugrotigotine patch

BOC CA13 ABCC8 CA3 CA5A CA7

2.80e-05931446CID003619466
DrugAC1L9LQQ

BOC CA13 CA3 CA5A CA7

3.03e-05571445CID000448224
DrugZinc chromate hydroxide

CA13 CA3 CA5A CA7

3.22e-05291444CID000027567
Drugthiadiazole

CA13 CA3 CA5A CA7

3.22e-05291444CID000067518
DrugFamotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A

PON1 NEB DOK4 SSH3 EFR3B GYG2 FGFR3 MAST3

3.62e-0519614485011_UP
DrugSuccinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

EMC1 SZT2 ATG2A DOK4 ABCC8 C3 SEMA4A OSGIN2

3.76e-0519714482821_UP
Drug2-MeImpU

POLR3E GYG2

3.97e-0521442CID000134922
Drugdimethadione

CA13 CA3 CA5A CA7

4.81e-05321444CID000003081
Drugbenzenesulfonamide

CA13 CA3 CA5A CA7

5.44e-05331444CID000007370
DrugMZ-m

CA13 CA3 CA5A CA7

5.44e-05331444CID000001798
Drugebrotidine

CA13 CA3 CA5A CA7

6.14e-05341444CID000065869
Drugp-nitrophenyl caprylate

BOC SLC6A7 LIPM

6.76e-05131443CID000097416
DrugDL-arginine

ACTB ACTG1 CA13 GRIN2C TIPARP KRIT1 POLR3E CA3 CA5A CA7

6.98e-0534414410CID000000232
DrugAC1LCVPZ

BOC ACTB PON1 ACTG1 PREP C3

7.20e-051101446CID000656926
Drugchlorthalidone

CA13 CA3 CA5A CA7

7.72e-05361444CID000002732
Drugcarbamoyl phosphate

ABO CA13 C3 CA3 CA5A CA7

8.36e-051131446CID000000278
DrugT2755

CA13 GRIN2C CA3 CA5A CA7

8.79e-05711445CID000005514
Drugchlorosyl

CYP4A11 DUSP5 ABCC8 XPR1

9.58e-05381444CID000166686
DrugBCECF

CA13 PTPRU CA3 CA5A CA7

1.00e-04731445CID004241719
Drugbendrofluazide

CA13 CA3 CA5A CA7

1.06e-04391444CID000002315
Drugindisulam

CA13 CA3 CA5A CA7

1.06e-04391444CID000216468
Drugsodium bicarbonate

CA13 PIK3C2A CA3 CA5A CA7

1.07e-04741445CID000010340
Drugbrinzolamide

CA13 CA3 CA5A CA7

1.18e-04401444CID000068844
Drugethoxzolamide

CA13 CA3 CA5A CA7

1.18e-04401444CID000003295
Drugdinophysistoxin-4

DTX1 DTX4

1.19e-0431442CID006441267
DrugTSTU

BOC C3

1.19e-0431442CID009857522
Drugtetracontane

CYP4A11 ALKBH3

1.19e-0431442CID000020149
DrugPeptidoglycan monomer

BOC ABO TLR6

1.58e-04171443CID003035036
DrugDB08219

CA13 CA3 CA5A CA7

1.71e-04441444CID011840966
Diseaseintestinal atresia (implicated_via_orthology)

ACTB ACTG1 FGFR2

1.20e-05101393DOID:10486 (implicated_via_orthology)
DiseaseCongenital neurologic anomalies

ACTB ACTG1 SPRED1

1.20e-05101393C0497552
DiseaseCranioschisis

ACTB ACTG1 SPRED1

1.20e-05101393C0265541
DiseaseBaraitser-Winter syndrome

ACTB ACTG1

2.20e-0521392cv:C1853623
DiseaseIsolated coronal synostosis

FGFR3 FGFR2

2.20e-0521392cv:CN043619
DiseaseIris Coloboma with Ptosis, Hypertelorism, and Mental Retardation

ACTB ACTG1

2.20e-0521392C1855722
DiseaseFryns-Aftimos Syndrome

ACTB ACTG1

2.20e-0521392C1853623
DiseaseAutism Spectrum Disorders

NSUN2 GTF2I TET1 USH2A IQGAP3

5.23e-05851395C1510586
DiseaseLacrimoauriculodentodigital syndrome

FGFR3 FGFR2

6.59e-0531392C0265269
Diseasediacylglycerol kinase beta measurement

PON1 C1R

6.59e-0531392EFO_0801525
DiseaseLevy-Hollister syndrome

FGFR3 FGFR2

6.59e-0531392cv:C0265269
Diseasecarbonic anhydrase 1 measurement

CA13 CA3

6.59e-0531392EFO_0020227
Diseasecerebral cavernous malformation (is_implicated_in)

PON1 KRIT1

6.59e-0531392DOID:0060669 (is_implicated_in)
DiseaseSaethre-Chotzen Syndrome

FGFR3 FGFR2

6.59e-0531392C0175699
DiseaseCongenital hypoplasia of radius

FGFR3 FGFR2

6.59e-0531392C0685381
DiseaseTWIST1-related craniosynostosis

FGFR3 FGFR2

1.31e-0441392cv:C4551902
Diseasebone disease (implicated_via_orthology)

FGFR3 FGFR2

2.18e-0451392DOID:0080001 (implicated_via_orthology)
DiseaseCCL25 measurement

ABO PIK3C2A

2.18e-0451392EFO_0010768
DiseaseParatuberculosis

C1R C3

3.26e-0461392C0030524
DiseaseX-14939 measurement

CYP4A11 CYP4A22

3.26e-0461392EFO_0800747
DiseaseCraniosynostosis syndrome

FGFR3 FGFR2

4.56e-0471392cv:C0010278
DiseaseUveoretinal Coloboma

ACTB ACTG1

4.56e-0471392C4554007
Diseasenemaline myopathy (implicated_via_orthology)

ACTB NEB

6.06e-0481392DOID:3191 (implicated_via_orthology)
DiseaseMoyamoya disease (implicated_via_orthology)

ACTB ACTG1

6.06e-0481392DOID:13099 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTB ACTG1

6.06e-0481392DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTB ACTG1

6.06e-0481392DOID:0081112 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTB ACTG1

6.06e-0481392DOID:14004 (implicated_via_orthology)
DiseaseCongenital ocular coloboma (disorder)

ACTB ACTG1

7.76e-0491392C0009363
Diseaseprotein intake measurement

ABO KLB

9.67e-04101392EFO_0010810
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTB ACTG1

9.67e-04101392DOID:13832 (implicated_via_orthology)
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

CYP4A11 CYP4A22

1.18e-03111392DOID:0110861 (biomarker_via_orthology)
DiseaseIntellectual Disability

CHL1 KIFBP FHIP2A NSUN2 WDR26 FGFR2 RAB39B EIF2A

1.31e-034471398C3714756
Diseasecraniosynostosis (is_implicated_in)

FGFR3 FGFR2

1.41e-03121392DOID:2340 (is_implicated_in)
DiseaseSpina Bifida

PON1 FGFR2

1.41e-03121392C0080178
Diseasedodecanedioate measurement

CYP4A11 XPR1

1.41e-03121392EFO_0021054
DiseaseStatus Dysraphicus

PON1 FGFR2

1.41e-03121392C0038219
DiseaseRachischisis

PON1 FGFR2

1.41e-03121392C0266508
Diseasecognitive inhibition measurement

TRPM6 PXDNL USH2A

1.71e-03501393EFO_0007969
DiseaseEpilepsy

ACTG1 FGFR3 RAB39B EIF2A

1.79e-031091394C0014544
Diseasesickle cell anemia (is_marker_for)

PON1 C3

1.93e-03141392DOID:10923 (is_marker_for)
Diseaseglucose measurement

ABO DUSP9 GRB14 EPB41L4A ARMC2 AXIN1 KDM2B

2.22e-033801397EFO_0004468
Diseasehip bone mineral density, hip bone size

NUP88 TMEM260 FGFR2

2.36e-03561393EFO_0004844, EFO_0007702
Diseaseisocitrate measurement

PREP TRPM8

2.53e-03161392EFO_0010505
DiseaseAmyotrophic Lateral Sclerosis

PON1 FIG4 SCFD1

2.61e-03581393C0002736
Diseasecreatine kinase measurement

ABO NEB IQGAP3

2.74e-03591393EFO_0004534
DiseaseKuhnt-Junius degeneration (is_implicated_in)

PON1 C3

2.86e-03171392DOID:10873 (is_implicated_in)
DiseaseBrachycephaly

FGFR3 FGFR2

2.86e-03171392C0221356
Diseasenon-Hodgkin lymphoma (is_implicated_in)

PON1 TMEM260

2.86e-03171392DOID:0060060 (is_implicated_in)
DiseaseMalignant neoplasm of endometrium

AXIN1 FGFR2

3.21e-03181392C0007103
Diseaselevel of Sphingomyelin (d34:1) in blood serum

USP24 NPFFR2

3.21e-03181392OBA_2045175
DiseaseCarcinoma in situ of endometrium

AXIN1 FGFR2

3.21e-03181392C0346191
DiseaseDisorder of eye

CYP27A1 PPT1 RIMS1 SEMA4A USH2A

3.37e-032121395C0015397
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

USP24 NOMO1

3.57e-03191392OBA_2045199
Diseasehip bone size

NUP88 TMEM260 FGFR2

3.61e-03651393EFO_0004844
Diseaseglycine measurement

ABO GRB14 GVINP1 MAST3

4.08e-031371394EFO_0009767
DiseaseProfound Mental Retardation

CHL1 KIFBP FGFR2 RAB39B

4.30e-031391394C0020796
DiseaseMental Retardation, Psychosocial

CHL1 KIFBP FGFR2 RAB39B

4.30e-031391394C0025363
DiseaseMental deficiency

CHL1 KIFBP FGFR2 RAB39B

4.30e-031391394C0917816
DiseaseCOVID-19 (is_implicated_in)

ABO C3

4.36e-03211392DOID:0080600 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
AELHLVHWNPKYNTF

CA3

116

P07451
KLPHAWIHTDASLVY

C16orf89

131

Q6UX73
YLTLSSIKDHPWHIQ

ARL5B

141

Q96KC2
IEAVWHDESHLNKYL

ABO

296

P16442
DHVVLLSGKWLYSHV

ADAM7

286

Q9H2U9
TLKYPIEHGIVTNWD

ACTB

66

P60709
TLKYPIEHGIVTNWD

ACTG1

66

P63261
DPDLKNYHKLHWETE

ARMC2

826

Q8NEN0
EHSEIHTKLYFLQWL

GVINP1

1336

Q7Z2Y8
QLWHPHEQDYKKSSL

GPR19

296

Q15760
TQADWQHRVPKEYHS

ALKBH3

251

Q96Q83
PNLSYIIGKDTWVEH

C3

1616

P01024
SWILYALATHPKHQE

CYP4A11

331

Q02928
AAELHVVHWNSDKYP

CA13

116

Q8N1Q1
SPEIWELLLKSVHLY

DPY19L3

501

Q6ZPD9
SAHSKHPEQWDLDYS

ANO2

721

Q9NQ90
ITIQHAYEKQHPWID

DTX4

111

Q9Y2E6
WILTAAHTLYPKEHE

C1R

496

P00736
SVDALTIHNHLWQPK

CAMSAP1

1576

Q5T5Y3
QYEHASIHLWDLLEG

CAPRIN1

206

Q14444
SEVPIWLDYHGKHVT

ATG2A

1671

Q2TAZ0
QKSEAYLPHTFWITL

ATP10D

1186

Q9P241
EHIIHMPQEDYISWL

CCDC60

521

Q8IWA6
ESIPHWIHEIEKYGA

RAB19

106

A4D1S5
HEWLEETKVHVQPYQ

RAB39B

101

Q96DA2
HPIWNVNDTKHHLYS

NPFFR2

116

Q9Y5X5
YEILATHPTWALKEA

NOMO3

181

P69849
HEHYLVHKPEKVTWT

CRYZL1

106

O95825
DCLKHHTVLPYHWQI

TIPARP

256

Q7Z3E1
YPEELAWHTNLSRKI

NSUN2

121

Q08J23
YSDAQPHIQWIKHVE

FGFR2

281

P21802
YEILATHPTWALKEA

NOMO2

181

Q5JPE7
LTEQYLHKDRWPEVS

MAP1A

1176

P78559
PLHIYWMNIELEHIE

CHL1

161

O00533
IYHKNIPEWAHVDFI

LIPM

376

Q5VYY2
YKDPATLRQHEKTHW

HIC1

516

Q14526
IAHNLYWLLKDALHD

PIK3C2A

1006

O00443
LHAADISHPTKQWLV

PDE1B

366

Q01064
LIHLDNHSLWEPKVF

EFR3B

256

Q9Y2G0
YEILATHPTWALKEA

NOMO1

181

Q15155
HYKQIPISDHWSQNL

DUSP9

251

Q99956
KSKAPHWTNRILHEY

KRIT1

591

O00522
SKIEQHLIFWLPAHD

GDPD4

356

Q6W3E5
NAYEKQHPWLDLSSL

DTX1

131

Q86Y01
VHTDPVHLYKNWINQ

IQGAP3

1071

Q86VI3
ETHIVDSPNYKLWHL

PTPRT

336

O14522
AVSLQTYKLWHLDPD

PTPRU

336

Q92729
ALLDDEPHWYKLQTH

RIMS1

856

Q86UR5
EPHWYKLQTHDESSL

RIMS1

861

Q86UR5
EWKFLPSLVNLHSAH

KICS2

206

Q96MD2
VHWFLDKTPLHANEL

OBSCN

3036

Q5VST9
LDDEPHWYKLQTHDV

RIMS2

921

Q9UQ26
HWYKLQTHDVSSLPL

RIMS2

926

Q9UQ26
WHDPIKEDVYRNHSI

PPT1

186

P50897
QHFEWLVKYSPLHNV

PREP

606

P48147
HLGEKYDEWVHQPVT

FA2H

136

Q7L5A8
NWSTTDIHKHLPFIY

GYG2

206

O15488
YDYPSVLHWKLEQHH

OSGIN2

101

Q9Y236
GAELQHITYSHWLPK

PXDNL

1006

A1KZ92
PAELHLVHWNSVKYQ

CA5A

151

P35218
WEYDPVKLTLQHVNS

GALNT1

506

Q10472
KWTDLALQYLHENVP

ANAPC13

56

Q9BS18
PTLHNLALYEEWVLS

KDM2B

266

Q8NHM5
DKYWHSISHLQPETS

BOC

771

Q9BWV1
LDTLTEHYDIPKVSW

FAM32A

96

Q9Y421
HLWELPTDFYLHHKN

FIG4

606

Q92562
PYLKWAESLHSLLDD

AXIN1

81

O15169
SWILYALATHPKHQE

CYP4A22

331

Q5TCH4
WALYHLSKDPEIQEA

CYP27A1

346

Q02318
HHWLYRLQEAPKKES

IFNL2

156

Q8IZJ0
THEVKQHPFFLALDW

MAST3

631

O60307
LEHWIFNSEAHLLPI

MAN1A1

626

P33908
VTLYHWDLPLALQEK

KLB

191

Q86Z14
LLILKNHYIDDHSWT

GRB14

136

Q14449
PLEYLEKLHYKHESW

DCK

201

P27707
FPSELHLVHWNAKKY

CA7

116

P43166
KLDHLHWPVFSDLDN

EEF2K

406

O00418
LKWVEHLPESDSIHY

EMC1

161

Q8N766
ILHKYDVPSNAELWQ

EIF2A

396

Q9BY44
KVYSDAQPHIQWLKH

FGFR3

276

P22607
PLQEDFVYHWKAITH

FHIP2A

21

Q5W0V3
HPENYDLATLKWILE

GTF2IRD2

156

Q86UP8
HPENYDLATLKWILE

GTF2IRD2B

156

Q6EKJ0
HPENYDLATLKWILE

GTF2I

161

P78347
SYQELVKVWHPDHNL

DNAJC22

296

Q8N4W6
HQTYWLDPAKTLAEH

EPB41L4A

66

Q9HCS5
KDIRWLSPHSALHVE

RUBCN

86

Q92622
LQKKHAEEPWVHLHY

POLR3E

196

Q9NVU0
THLHYKWIPVEDSHT

DUSP5

221

Q16690
KLQITHENIYLWDIH

DOK4

156

Q8TEW6
HENIYLWDIHNPRVK

DOK4

161

Q8TEW6
KRQLEHNAYHPIEWA

KIFBP

236

Q96EK5
LESYPLNAHCEWTIH

PAMR1

141

Q6UXH9
LTLKHAAWYPSEILD

NUP88

171

Q99567
GTVDLQHVLEHWYLL

SYT8

221

Q8NBV8
KYVLHSVDLQSENPW

SYVN1

191

Q86TM6
PGIWKHLQDLTYSEI

SZT2

921

Q5T011
SHVIGHLKPNTEYWI

USH2A

2981

O75445
WTIEAPEGQKLHLHF

SEZ6L

481

Q9BYH1
IDHDITSQLYAWPLL

TBC1D31

561

Q96DN5
HVYEKHANWTLTPLK

PON1

246

P27169
KPFEEHWRKHTLSYV

SDHA

616

P31040
PVLKTDNFLRWLHHD

SEMA4A

216

Q9H3S1
EEPHYIEIWKKHLEA

SECISBP2

816

Q96T21
LHIPWSYEDSLTIAQ

PGAP1

526

Q75T13
WDPLSTDYLLVVNLH

WDR17

231

Q8IZU2
LELLKHNEAYTWTNP

OSBPL2

221

Q9H1P3
TPQFHHLLSSKVWIE

SLC6A7

276

Q99884
AQLLPHWKETHRFIE

SSH3

386

Q8TE77
YLDEKQHAWLPLTIE

TCL1A

26

P56279
KLPHIDEYWSDSEHI

TET1

1986

Q8NFU7
VTHKLQYLPHADWII

ABCC8

886

Q09428
KEHVPTWLQNTHVYS

TRAF3IP2

526

O43734
YQIIETAHWKHPIFS

CNBD2

46

Q96M20
HLTISHGPWIDEEYK

NLRP9

971

Q7RTR0
HLSAHITPEWRKQYI

XPR1

6

Q9UBH6
LHHWVPVAETKFLVA

XYLT1

826

Q86Y38
KHILIYEQHWKPDAL

TRPM6

426

Q9BX84
LYHLLSPWAHSANKD

TBC1D8B

846

Q0IIM8
WALTPTHYLTKHDVE

RPN2

21

P04844
KWDEINILATYHPAD

PPP1R2B

46

Q6NXS1
KHLWLEFSHPVESLA

SPIRE2

521

Q8WWL2
IYNKVTPTFHHWKID

SPRED1

81

Q7Z699
DLATPLHHTWTYQAL

SCFD1

266

Q8WVM8
FAAEDSVQWLLKHHP

PPP1R36

46

Q96LQ0
CHLKWLADYLHTNPI

SLIT2

436

O94813
EFVVWNPRSHEKLHI

WDR6

636

Q9NNW5
HDSAWVKSELVPYLE

TLR6

651

Q9Y2C9
LWEEQLHSYPHKDQL

YLPM1

461

P49750
YRIFHSWLQPEKHSK

ZSCAN4

66

Q8NAM6
LESRVLTDHWSIPYK

USP24

131

Q9UPU5
LTDHWSIPYKREESL

USP24

136

Q9UPU5
SHLLTEPVKDHNWRY

TRIM16

116

O95361
SDYIIHQTVHTWKKP

ZNF23

601

P17027
EDHKVYIWHKRSELP

WDR26

591

Q9H7D7
HSYPGKQDHLWIIIE

TEX15

1846

Q9BXT5
AEILYELLTQHWHLK

TRPM8

126

Q7Z2W7
EKSYQVISWLAPEDH

UGT3A2

71

Q3SY77
LSTYLETHNWPEALK

TRMT10B

286

Q6PF06
NLEWLHLAKHEAIVY

WDR87

2561

Q6ZQQ6
KEHLSSPVYIWDLAR

TMEM14EP

61

Q6UXP3
LTVWKELEQKPTHHY

WDR81

1851

Q562E7
TPHSWEEELNHYALK

ZMYM4

1101

Q5VZL5
KEIVYLQKEHPVNWH

TMEM260

626

Q9NX78
KSFYWKAHLIQHERP

ZNF658B

151

Q4V348
VLKLWHNSITYIPEH

LRRC8C

641

Q8TDW0
NSIWPLKALDHHVIS

LRRIQ3

146

A6PVS8
TLVSDVDYKHPLHEW

NEB

3346

P20929
VSDIDYKHPLHEWTC

NEB

3591

P20929
CYVWDTPEILHAKHA

NEB

4856

P20929
EHLVYWKLRHSVPNS

GRIN2C

836

Q14957