Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionrRNA (cytosine-N4-)-methyltransferase activity

METTL15 METTL15P1

2.81e-062342GO:0071424
GeneOntologyMolecularFunctionrRNA (cytosine) methyltransferase activity

METTL15 METTL15P1

4.20e-056342GO:0016434
DomaincNMP

KCNH7 RAPGEF2

1.45e-0334312SM00100
DomaincNMP_binding

KCNH7 RAPGEF2

1.45e-0334312PF00027
DomaincNMP-bd_dom

KCNH7 RAPGEF2

1.53e-0335312IPR000595
DomainCNMP_BINDING_3

KCNH7 RAPGEF2

1.53e-0335312PS50042
DomaincNMP-bd-like

KCNH7 RAPGEF2

1.81e-0338312IPR018490
DomainKinase-like_dom

TEX14 RIOK2 TRRAP CLK3 CLK4

1.84e-03542315IPR011009
Domain-

KCNH7 RAPGEF2

2.87e-03483122.60.120.10
DomainRmlC-like_jellyroll

KCNH7 RAPGEF2

3.23e-0351312IPR014710
DomainProt_kinase_dom

TEX14 RIOK2 CLK3 CLK4

8.34e-03489314IPR000719
DomainPROTEIN_KINASE_DOM

TEX14 RIOK2 CLK3 CLK4

8.58e-03493314PS50011
Pubmed

METTL15 interacts with the assembly intermediate of murine mitochondrial small ribosomal subunit to form m4C840 12S rRNA residue.

METTL15 METTL15P1

9.28e-07234232573735
Pubmed

Mitochondrial rRNA Methylation by Mettl15 Contributes to the Exercise and Learning Capability in Mice.

METTL15 METTL15P1

9.28e-07234235682734
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

KDM3B DDX23 NCOR1 ZNF326 TRRAP

2.32e-0622034535785414
Pubmed

Reduced retinoic acid-sensitivities of nuclear receptor corepressor binding to PML- and PLZF-RARalpha underlie molecular pathogenesis and treatment of acute promyelocytic leukemia.

NCOR1 ZBTB16

2.78e-0633429531570
Pubmed

The Transcription Factor PLZF Is Necessary for the Development and Function of Mouse Basophils.

ZBTB16 IL18R1

2.78e-06334231366712
Pubmed

The integrity of the charged pocket in the BTB/POZ domain is essential for the phenotype induced by the leukemia-associated t(11;17) fusion protein PLZF/RARalpha.

NCOR1 ZBTB16

5.56e-06434216024608
Pubmed

Characterization and comparison of four serine- and arginine-rich (SR) protein kinases.

CLK3 CLK4

5.56e-0643429307018
Pubmed

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage.

ZBTB16 IL18R1

9.26e-06534227668799
Pubmed

Critical residues within the BTB domain of PLZF and Bcl-6 modulate interaction with corepressors.

NCOR1 ZBTB16

9.26e-06534211865059
Pubmed

Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells.

CLK3 CLK4

9.26e-06534219168442
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

NCOR1 ZNF326 TRRAP WDR33

1.25e-0514634423892456
Pubmed

H3K9 Demethylases JMJD1A and JMJD1B Control Prospermatogonia to Spermatogonia Transition in Mouse Germline.

KDM3B ZBTB16

1.39e-05634232679061
Pubmed

AML-associated translocation products block vitamin D(3)-induced differentiation by sequestering the vitamin D(3) receptor.

NCOR1 ZBTB16

1.39e-05634212460926
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KDM3B ZNF326 ZBTB16 RAPGEF2 ARHGEF10 CLK3 STARD9

1.67e-0586134736931259
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

KDM3B DDX23 NCOR1 TRRAP WDR33

1.94e-0534134532971831
Pubmed

Role of promyelocytic leukemia zinc finger (PLZF) in cell proliferation and cyclin-dependent kinase inhibitor 1A (p21WAF/CDKN1A) gene repression.

NCOR1 ZBTB16

3.33e-05934224821727
Pubmed

DNA cross-link repair safeguards genomic stability during premeiotic germ cell development.

ZBTB16 FAN1

3.33e-05934231367016
Pubmed

Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.

NCOR1 TRRAP

4.15e-051034212738788
Pubmed

Distinct, dosage-sensitive requirements for the autism-associated factor CHD8 during cortical development.

METTL15 METTL15P1

5.07e-051134233627187
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

DDX23 NCOR1 MPHOSPH10 TEX14 ANK2 GUCY1A2 WDR33 STARD9

5.93e-05144234835575683
Pubmed

An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.

KDM3B NCOR1

7.19e-051334218986647
Pubmed

PRSS50 is a testis protease responsible for proper sperm tail formation and function.

ZBTB16 TEX14

8.38e-051434233913480
Pubmed

The histone deacetylase 9 gene encodes multiple protein isoforms.

NCOR1 ZBTB16

8.38e-051434212590135
Pubmed

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.

DDX23 ZNF326 WDR33

9.15e-058934322446626
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

ZNF326 MPHOSPH10 RIOK2 WDR33

1.04e-0425134428077445
Pubmed

Analysis of Pax6 contiguous gene deletions in the mouse, Mus musculus, identifies regions distinct from Pax6 responsible for extreme small-eye and belly-spotting phenotypes.

METTL15 METTL15P1

1.57e-041934219474196
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RAP1GDS1 RAPGEF2 ANK2 CLIP2 ARHGEF10 USP32 FAN1

2.07e-04128534735914814
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

DDX23 ZNF326 ANK2 CLIP2 RIOK2 WDR33 STARD9

3.08e-04137134736244648
Pubmed

Control of developmentally primed erythroid genes by combinatorial co-repressor actions.

NCOR1 TRRAP

3.97e-043034226593974
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

ZNF326 MPHOSPH10 WDR33 CLK3

4.54e-0437034422922362
Pubmed

Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.

ANK2 CLIP2

6.05e-043734227565344
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

DDX23 ZNF326 MPHOSPH10 WDR33 CLK3

6.07e-0471334529802200
Pubmed

Nucleolar proteome dynamics.

KDM3B DDX23 ZNF326 MPHOSPH10

7.23e-0441934415635413
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

KDM3B TRRAP

7.79e-044234235705031
GeneFamilyCDC like kinases

CLK3 CLK4

9.27e-064232480
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L3HYPDH RAPGEF2 IL18R1 FAN1

6.74e-06161344334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCellfacs-Marrow-B-cells-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

L3HYPDH RAPGEF2 IL18R1 FAN1

6.74e-0616134481d44438e4be4e68a59247e62f02026301a8a0c5
ToppCellHealthy_donor-NK_CD56bright|Healthy_donor / disease group, cell group and cell class (v2)

IFITM2 ZBTB16 IL18R1 STARD9

1.27e-051893449eac380a3bb4b685effb52d816e1960972660646
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IFITM2 ZBTB16 ARHGEF10 IL18R1

1.55e-051993445f67ea58512856cbdcef759088a5869720a947a8
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

KDM3B IFITM2 IL18R1

1.86e-041463438b2d104fdb0fdb09410450c6c651e1edb00cae44
ToppCell10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-|Lung / Manually curated celltypes from each tissue

IFITM2 ZBTB16 IL18R1

2.39e-04159343595643e9433265308e5aab7f906229025701cf6a
ToppCellInfluenza_Severe-Neutrophil|Influenza_Severe / Disease group and Cell class

ABCA1 IFITM2 IL18R1

2.48e-0416134398c95b1b85d5427415af2ca8fb14849e97f6e8b5
ToppCellInfluenza_Severe-NK_CD56bright|Influenza_Severe / Disease group and Cell class

ARHGEF10 METTL15 IL18R1

2.57e-041633437748d5709e8cf6673f5a8370108309f76cd830f4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZBTB16 IL18R1 STARD9

2.62e-04164343f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCellHealthy-NK_CD56bright|Healthy / disease group, cell group and cell class

IFITM2 IL18R1 STARD9

2.62e-04164343ed193211965accba60a256d3e6c159f0fc911d8b
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFITM2 ZBTB16 IL18R1

2.76e-0416734394642b3dae035fedb6e8b9745f440096a4539f3c
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFITM2 ZBTB16 IL18R1

2.76e-0416734342b299273a6c72a625b204d55f4f3c4eebd6d185
ToppCellHealthy-NK_CD56bright|World / disease group, cell group and cell class

IFITM2 IL18R1 STARD9

2.76e-04167343ab7a570a75ee2018b9fe886cdec79cda27f1563f
ToppCellBAL-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IFITM2 ZBTB16 IL18R1

2.76e-04167343ecf5bc634e1e01efd783617eb81d1704e903ea21
ToppCellInfluenza_Severe-Neutrophil|World / Disease group and Cell class

ABCA1 IFITM2 IL18R1

2.86e-041693436e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCellT_cells-CD56_bright_CD16-_NK_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

ZBTB16 IL18R1 STARD9

3.01e-04172343980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCellsevere_influenza-Neutrophil|severe_influenza / disease group, cell group and cell class (v2)

ABCA1 IFITM2 IL18R1

3.06e-04173343615e266419b9f06e964eff73cb466f05451ba0dd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Degenerative_Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANK2 ARHGEF10 ANKRD18B

3.11e-0417434346bd0ef7d0541386de7a901d85d53d0176dc92bf
ToppCellIPF-Lymphoid-ILC_A|Lymphoid / Disease state, Lineage and Cell class

IFITM2 ZBTB16 IL18R1

3.17e-04175343b6d1e40d9339426d778481fd67ab7cbc0f6cb5b2
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZBTB16 ARHGEF10 IL18R1

3.17e-04175343cc2428150987911d0d382e8177918724aa69f85c
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZBTB16 IL18R1 ANKRD18B

3.27e-04177343605f71515c877bb4de4121675ec8c1318a2500a7
ToppCell21-Trachea-Immune-Hematopoietic,_Natural_Killer_Cell|Trachea / Age, Tissue, Lineage and Cell class

IFITM2 ZBTB16 IL18R1

3.33e-04178343d2e1f6b7933b7da2682393e5ff5e03cdd8f64761
ToppCellControl-T/NK-NK|Control / Disease group,lineage and cell class （2021.01.30）

IFITM2 ZBTB16 IL18R1

3.33e-04178343079fd19bdeed86bf985c4083af432432d66ad546
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-ILC_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ZBTB16 RAPGEF2 IL18R1

3.38e-04179343d18a520568cf4b031972d3dd7d4d4bd073ac1fea
ToppCellSevere-B_naive-12|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ABCA1 IFITM2 ZBTB16

3.44e-04180343bc20e581d37cba72b71ef62df60475a0ccee9994
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANK2 GUCY1A2 METTL15

3.50e-04181343274c0b768925cd5804483303f8c5ebd17a534c41
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TEX14 ARHGEF10 FAN1

3.61e-041833433ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

NCOR1 ZBTB16 MARCHF5

3.73e-04185343857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RAPGEF2 CLK3 USP32

3.73e-04185343e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_bright-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFITM2 ZBTB16 IL18R1

3.73e-041853433b2da51aec057b462749ae39afb8f253afcf38d5
ToppCellIIH-NK|IIH / Condition, Cell_class and T cell subcluster

IFITM2 ZBTB16 IL18R1

3.79e-04186343cab1249b849013cf0334f25ee8d840f0521f4eb8
ToppCellIIH-NK-|IIH / Condition, Cell_class and T cell subcluster

IFITM2 ZBTB16 IL18R1

3.79e-041863432c90b45c8ccfd86bbf6840dba7f0d7f08b5ea914
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA1 IFITM2 IL18R1

3.79e-04186343de55471dd5c842026b409cfebf67fe32f079a011
ToppCellInfluenza-Influenza_Severe-Myeloid-Neutrophil|Influenza_Severe / Disease, condition lineage and cell class

ABCA1 IFITM2 IL18R1

3.79e-041863431dfcec9196d4db76fba3abc74e85885b1fb98b87
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 ANK2 FAM151A

3.91e-04188343a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZBTB16 GUCY1A2 STARD9

3.91e-04188343ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellHealthy_donor-NK_CD56bright|World / disease group, cell group and cell class (v2)

IFITM2 IL18R1 STARD9

3.91e-041883438ee359199c61c3b5b498ac35148390db5cc1a836
ToppCell3'_v3-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

IFITM2 ZBTB16 IL18R1

3.97e-041893436e402fb3fc31e4cb541e3cd140d7a86c1083dbf5
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

IFITM2 RAPGEF2 GUCY1A2

4.03e-04190343a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellSevere-MAIT|World / Disease group and Cell class

ABCA1 ZBTB16 IL18R1

4.03e-041903437a92e0d6a021be23125495927b8571e25c83204a
ToppCellSevere-MAIT|Severe / Disease group and Cell class

ABCA1 ZBTB16 IL18R1

4.03e-041903431c063dc1b62d9f9912aaf8d0297555a6545f5550
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IFITM2 IL18R1 STARD9

4.09e-041913437a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCellControl-Lymphoid_T/NK-NK_CD56bright|Control / Disease group, lineage and cell class

IFITM2 IL18R1 STARD9

4.09e-04191343e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFITM2 IL18R1 STARD9

4.09e-04191343f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

ZBTB16 IL18R1 STARD9

4.09e-0419134370c067c54084bfb02c29bab085f4defd477194fb
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFITM2 IL18R1 STARD9

4.09e-04191343c023ca893ceae19b54967096f6e2588dc39fa268
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFITM2 IL18R1 STARD9

4.09e-041913431161e465c50c2071764279e01cf08b1048cce0e3
ToppCellCOVID-19-kidney-Myeloid|kidney / Disease (COVID-19 only), tissue and cell type

ABCA1 IFITM2 IL18R1

4.15e-04192343441cd1ec171f643b28e1f6f9c04def629cc7391b
ToppCellCOVID-19-Myeloid-MoAM1,_IL1R2|Myeloid / Condition, Lineage and Cell class

IFITM2 ZBTB16 RAPGEF2

4.15e-04192343be9d5685fa03563322f147a4b38ed31e4da59487
ToppCellnormal_Pleural_Fluid-T/NK_cells-NK|normal_Pleural_Fluid / Location, Cell class and cell subclass

IFITM2 ZBTB16 STARD9

4.15e-0419234359dd4f5ae9f1cca78adf60b71661092ef09e6641
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ABCA1 FAM151A

4.15e-041923431304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellT/NK_cells-CD56bright_NK_cell|World / Lineage and Cell class

IFITM2 ZBTB16 IL18R1

4.15e-04192343528b5b790a0e8966d04ffbc83b049c93bac17537
ToppCelldroplet-Thymus-nan-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 WDR33 CLK3

4.22e-0419334381871f4f2b63ca5f64a9ff12f6c909a34bf52216
ToppCelldroplet-Thymus-nan-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 WDR33 CLK3

4.22e-0419334312380713db6582749183a19de65d4af9d6469a3f
ToppCellMild_COVID-19-T/NK-NK|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

IFITM2 ZBTB16 IL18R1

4.22e-041933439c455d9d845fa230e9a61d9a5f9d6a2ccf5d7350
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFITM2 GUCY1A2 ARHGEF10

4.22e-041933432483bb7f398e4fa0ef09c8bd584ed25703853f03
ToppCellICU-SEP-Lymphocyte-T_NK-NK|ICU-SEP / Disease, Lineage and Cell Type

IFITM2 ZBTB16 ARHGEF10

4.22e-04193343f110f86db305e41639087f5b1a2dff103c07adf0
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

ABCA1 IFITM2 ZBTB16

4.22e-041933433479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellILEUM-inflamed-(6)_ILC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IFITM2 ZBTB16 METTL15

4.28e-041943434d51d49366c34ff1241770b4acc0167a43b3155a
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ANK2 FAM151A

4.28e-041943430b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell10x5'-bone_marrow-Lymphocytic_NK-NK_CD56bright_CD16-|bone_marrow / Manually curated celltypes from each tissue

IFITM2 RAP1GDS1 ZBTB16

4.28e-041943435c58a2d1dd3c8ff77ce44d473239685e6b020909
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ABCA1 FAM151A

4.28e-0419434392b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellBLOOD--(0)_NK_cells_(CD56bright-like)| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

IFITM2 ZBTB16 IL18R1

4.28e-041943438d4368d546bba17a420e172bfb5f1f337fe23c44
ToppCellT/NK_cells-CD56bright_NK_cell|T/NK_cells / Lineage and Cell class

IFITM2 ZBTB16 IL18R1

4.35e-04195343d2c8f5c114b1864b509fad449aa4492dfc61113c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFITM2 ZBTB16 IL18R1

4.35e-04195343609732e83ab7fc3ba7dace66f5a17e46557fd6d1
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFITM2 ZBTB16 IL18R1

4.35e-04195343acc603dc94ac6518adb0dffb43305b380ec75b52
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFITM2 ZBTB16 IL18R1

4.35e-041953434eb13aa9fc496caca6e0a4fb80d11a60cf2511b0
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IFITM2 ZBTB16 IL18R1

4.35e-04195343234666fb7a1fd7e33bb7e54fd4004649ce22de70
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFITM2 ZBTB16 IL18R1

4.35e-0419534390c77b7f245b1bf80ba293583f8fe343b14c7f67
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ABCA1 FAM151A

4.35e-041953433e519cffa6144a62b06124642a14c9ff39b76554
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

IFITM2 ZBTB16 IL18R1

4.35e-0419534372f42f0be53a2a61f61647118b4883e752d998a5
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFITM2 ZBTB16 IL18R1

4.35e-04195343f0fb039f3d2e36acb258afb8b6d2fed20c395c36
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

IFITM2 ZBTB16 IL18R1

4.35e-04195343c7743d8c57584d29cca69c6405f1df6718174582
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

ABCA1 IFITM2 ZBTB16

4.35e-04195343fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR1 ABCA1 FAM151A

4.35e-041953437796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellBAL-Mild-Lymphocyte-T/NK-NK_cell-NK-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IFITM2 ZBTB16 IL18R1

4.35e-0419534389d832d1715f2720caa8cdd1e7ef847d79642556
ToppCellnormal-na-Lymphocytic_NK|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFITM2 ZBTB16 IL18R1

4.35e-04195343cebe79c42af5910353ba9ad7d0edb01982f772a3
ToppCellCOVID-19_Severe-PLT_4|World / Disease Group and Platelet Clusters

ZNF326 WDR33 CLK4

4.41e-04196343ad43efdd4d73b6615f65f06a315b33576e317473
ToppCellnormal_Lymph_Node-T/NK_cells-NK|normal_Lymph_Node / Location, Cell class and cell subclass

IFITM2 ZBTB16 IL18R1

4.41e-0419634300ab4a1547752d419aa720b39b94a4ab2ede963a
ToppCell3'-Distal_airway-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.48e-041973439ffb823c0f3f23cc85f9fd3ca24f77817e90bd86
ToppCellVE-NK|VE / Condition, Cell_class and T cell subcluster

IFITM2 ZBTB16 IL18R1

4.48e-04197343cae6ff8763501e7a5897b50188ac2640d65a47c0
ToppCelllymphoid-T_cell-Regulatory_T_cell|lymphoid / Lineage, cell class and subclass

IFITM2 ZBTB16 IL18R1

4.48e-0419734373d5dcf076caae60ea32258b4e9dcac8979a661e
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.48e-04197343ca6bce1a92c6326f41a6300c31da02386bafa152
ToppCellVE-NK-|VE / Condition, Cell_class and T cell subcluster

IFITM2 ZBTB16 IL18R1

4.48e-04197343ee89b8521fb4faaed9e4d39f7171e45eccf38b00
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.48e-041973436ac8d3e3f573e3848ab33e4df66dfaf8f948ea6c
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFITM2 ZBTB16 IL18R1

4.48e-0419734373a33d8b27043ba3074d04bc2d18cd287e00117f
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IFITM2 ZBTB16 IL18R1

4.48e-04197343dfec2afd1cbe218c9234ce7d4b5a5839b268398d
ToppCellnormal-na-Lymphocytic_NK-natural_killer_cell-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

IFITM2 ZBTB16 IL18R1

4.48e-04197343994d3289a5dd1a89fbcf28a6263e3784ccf732df
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.48e-04197343e3be7758a92f12e0a423394822957e1b7f995110
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.54e-041983435eedcc20e35adbabe268a93b748ee4566b3ffb66
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.54e-041983433aae7d146ebbb34da3239041a7c0334abff2597f
ToppCellSevere-Lymphoid-NK|Severe / Condition, Lineage, Cell class and cell subclass

L3HYPDH ZBTB16 IL18R1

4.54e-0419834326b6d20527d22ce68067cdaea6b4330cb779f91b
ToppCellCOVID-19_Severe-PLT_4|COVID-19_Severe / Disease Group and Platelet Clusters

ZNF326 WDR33 CLK4

4.54e-04198343abfddbee99ef8c7719e6e6f62571e9be030e4acf
ToppCelllymphoid-T_cell-Regulatory_T_cell|T_cell / Lineage, cell class and subclass

IFITM2 ZBTB16 IL18R1

4.54e-041983436773c6043ef4a3d9e9700330b6386431ee66abdc
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.54e-041983432400f8b8c51739ea2ae2b9f24f44eaeefa2bb6fc
ToppCelldistal-1-Endothelial-Capillary|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IFITM2 ZBTB16 IL18R1

4.61e-041993434b22769882fdd83f9cdca59e4d39ef441e62856b
ToppCellInfluenza-Influenza_Severe-Lymphocyte-T/NK-NK_CD56bright|Influenza_Severe / Disease, condition lineage and cell class

ARHGEF10 METTL15 IL18R1

4.61e-04199343784e7e7ede2baa28ede600834813e6de2240bfdf
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.61e-041993438db1acdcabf97f01b9ca17456c48ec8ac4928390
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFITM2 ZBTB16 IL18R1

4.61e-041993436cfe5a3d0ad530411ebc11decb4ab4c529e018d5
ToppCellSigmoid-(3)_ILC|Sigmoid / shred on region, Cell_type, and subtype

IFITM2 ZBTB16 IL18R1

4.68e-04200343a7326c43987a5eb4f4f5b48c4252cf4870432e5d
Diseaseneutrophil measurement

IFITM2 ZBTB16 GFM1 IL18R1

5.04e-05177344EFO_0803548
Diseaseanxiety disorder (implicated_via_orthology)

KDM3B NCOR1

2.93e-0422342DOID:2030 (implicated_via_orthology)
Diseasetriacylglycerol 54:3 measurement

MPHOSPH10 CLIP2

5.87e-0431342EFO_0010421
DiseaseGastric Adenocarcinoma

TEX14 TRRAP

1.24e-0345342C0278701
DiseaseHOMA-B

ABCA1 ARHGEF10

1.84e-0355342EFO_0004469
Diseasecoronary artery disease

ABCA1 MPHOSPH10 KCNH7 RAPGEF2 GUCY1A2 WDR33

2.20e-031194346EFO_0001645
Diseasethyroxine measurement

NCOR1 STARD9

4.14e-0383342EFO_0005130

Protein segments in the cluster

PeptideGeneStartEntry
VGHMPVMVAKQQEFK

ARHGEF10

881

O15013
IMIQKHKADMGVNVG

GSDMC

86

Q9BYG8
EEKEEEMVVLVVMGG

H2AL3

121

A0A3B3IU63
KHVKAEMEQMALDVG

ABCA1

1006

O95477
THMEKDMVELGKVQE

ANKRD18B

816

A2A2Z9
ENREHLVMMEKILGP

CLK3

526

P49761
IGELKAVMEGIKMEH

CLIP2

646

Q9UDT6
AVMEGIKMEHQLELG

CLIP2

651

Q9UDT6
EGTEKEEIMVQGMPQ

ANK2

3911

Q01484
IHEEKEMRIMTPEGK

IL18R1

261

Q13478
MLKEEQEVAMLGVPH

IFITM2

21

Q01629
HIIPVKNQEGVAMMF

KCNH7

111

Q9NS40
VKEMVMGLNVLDPHT

KDM3B

1366

Q7LBC6
VMQVVGHKEGLDVME

MARCHF5

121

Q9NX47
AEEENPEHVEIQKMM

MPHOSPH10

486

O00566
ETMAKLHIPVMVDEV

METTL15P1

66

P0C7V9
DMGFEPDVQKILEHM

DDX23

556

Q9BUQ8
ETMAKLHIPVMVDEV

METTL15

66

A6NJ78
AMVEKMHELVGGVPQ

FAM151A

226

Q8WW52
IHMVDNGIVEKLMDL

RAP1GDS1

351

P52306
MDGMHVAVKIVKNVG

CLK4

181

Q9HAZ1
MHEVKGKDGVGAVMD

GFM1

76

Q96RP9
DKVMEVKGQMIHVPE

GUCY1A2

401

P33402
IPEHMVRGSKIMEAE

FAN1

226

Q9Y2M0
DMEIIELKEMGSQPH

TEX14

556

Q8IWB6
DDKVEDHGVVMSQPM

NCOR1

2276

O75376
IQEMEMGVKQPHQMV

STARD9

931

Q9P2P6
LMVDVPGHGKVMVDI

L3HYPDH

171

Q96EM0
NMQKVEEEGEIVMVK

RAPGEF2

241

Q9Y4G8
PGVAEVKTEMMQVDE

ZBTB16

236

Q05516
TAVEMGMKNHEIVPG

RIOK2

21

Q9BVS4
VGVEKEVGGMEMAHE

WDR33

361

Q9C0J8
TVIMEPHKEVLQDMV

TRRAP

1276

Q9Y4A5
MERMLHVVDGKVPDT

USP32

116

Q8NFA0
EGVTVDDHMMKVETV

ZNF326

391

Q5BKZ1