Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	intracellularly cGMP-activated cation channel activity	CNGA1 CNGA2 CNGA3	1.60e-05	7	156	3	GO:0005223
GeneOntologyMolecularFunction	intracellularly cAMP-activated cation channel activity	CNGA1 CNGA2 CNGA3	5.39e-05	10	156	3	GO:0005222
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	RYR2 CNGA1 CNGA2 CNGA3	1.23e-04	33	156	4	GO:0005217
GeneOntologyMolecularFunction	poly(A)-specific ribonuclease activity	CNOT6 CNOT6L CNOT2	1.26e-04	13	156	3	GO:0004535
GeneOntologyMolecularFunction	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	CNGA1 CNGA2 CNGA3	1.26e-04	13	156	3	GO:0005221
GeneOntologyMolecularFunction	cyclic nucleotide-activated monoatomic ion channel activity	CNGA1 CNGA2 CNGA3	1.26e-04	13	156	3	GO:0043855
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP1 LRP2 SORL1	2.43e-04	16	156	3	GO:0005041
GeneOntologyMolecularFunction	cGMP binding	CNGA1 CNGA2 CNGA3	2.43e-04	16	156	3	GO:0030553
GeneOntologyMolecularFunction	zinc ion sequestering activity	S100A7 S100A7A	3.60e-04	4	156	2	GO:0140486
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP1 LRP2 SORL1	5.61e-04	21	156	3	GO:0030228
GeneOntologyMolecularFunction	opioid peptide activity	PDYN ZNF106	5.97e-04	5	156	2	GO:0001515
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	AGAP5 RAPGEF6 RALGPS2 DOCK10 ECT2L ALS2 AGAP11 BCR ARHGAP25 AGAP9 AGAP1 PLCE1	6.50e-04	507	156	12	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	AGAP5 RAPGEF6 RALGPS2 DOCK10 ECT2L ALS2 AGAP11 BCR ARHGAP25 AGAP9 AGAP1 PLCE1	6.50e-04	507	156	12	GO:0030695
GeneOntologyMolecularFunction	small GTPase binding	RAPGEF6 RHOBTB3 DVL3 DOCK10 ALS2 FMNL2 CDC42BPB PLCE1 SORL1	9.70e-04	321	156	9	GO:0031267
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	AGAP5 RAPGEF6 DVL3 DOCK10 ALS2 AGAP11 BCR RSU1 ARHGAP25 AGAP9 AGAP1	2.78e-06	244	157	11	GO:0043547
GeneOntologyBiologicalProcess	positive regulation of cytoplasmic mRNA processing body assembly	CNOT6 CNOT6L CNOT2	8.51e-06	6	157	3	GO:0010606
GeneOntologyBiologicalProcess	regulation of cytoplasmic mRNA processing body assembly	CNOT6 CNOT6L CNOT2	2.36e-05	8	157	3	GO:0010603
GeneOntologyBiologicalProcess	P-body assembly	CNOT6 CNOT6L TNRC6A CNOT2	2.56e-05	23	157	4	GO:0033962
GeneOntologyBiologicalProcess	regulation of GTPase activity	AGAP5 RAPGEF6 DVL3 DOCK10 ALS2 AGAP11 BCR RSU1 ARHGAP25 AGAP9 AGAP1	5.35e-05	335	157	11	GO:0043087
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA catabolic process	CNOT6 CNOT6L DCP1B TNRC6A PNRC1 ATM CNOT2	6.89e-05	132	157	7	GO:0000956
GeneOntologyBiologicalProcess	nuclear-transcribed mRNA poly(A) tail shortening	CNOT6 CNOT6L TNRC6A CNOT2	1.11e-04	33	157	4	GO:0000289
GeneOntologyCellularComponent	intracellular cyclic nucleotide activated cation channel complex	CNGA1 CNGA2 CNGA3	1.42e-05	7	157	3	GO:0017071
GeneOntologyCellularComponent	CCR4-NOT complex	CNOT6 CNOT6L CNOT2	2.17e-04	16	157	3	GO:0030014
Domain	CLZ	CNGA1 CNGA2 CNGA3	2.36e-06	4	158	3	PF16526
Domain	CLZ_dom	CNGA1 CNGA2 CNGA3	2.36e-06	4	158	3	IPR032406
Domain	Ldl_recept_b	LRP1 LRP2 LRP5 SORL1	4.62e-06	14	158	4	PF00058
Domain	LDLRB	LRP1 LRP2 LRP5 SORL1	4.62e-06	14	158	4	PS51120
Domain	-	AGAP5 RALGPS2 DOCK10 ECT2L ALS2 AGAP11 BCR PLEKHD1 CDC42BPB DCP1B ARHGAP25 AGAP9 AGAP1 PLCE1	6.15e-06	391	158	14	2.30.29.30
Domain	LY	LRP1 LRP2 LRP5 SORL1	6.26e-06	15	158	4	SM00135
Domain	LDLR_classB_rpt	LRP1 LRP2 LRP5 SORL1	6.26e-06	15	158	4	IPR000033
Domain	PH_dom-like	AGAP5 RALGPS2 DOCK10 ECT2L ALS2 AGAP11 BCR PLEKHD1 CDC42BPB DCP1B ARHGAP25 AGAP9 AGAP1 PLCE1	1.62e-05	426	158	14	IPR011993
Domain	PH	AGAP5 RALGPS2 DOCK10 ALS2 AGAP11 BCR PLEKHD1 CDC42BPB ARHGAP25 AGAP9 AGAP1	2.54e-05	278	158	11	SM00233
Domain	PH_DOMAIN	AGAP5 RALGPS2 DOCK10 ALS2 AGAP11 BCR PLEKHD1 CDC42BPB ARHGAP25 AGAP9 AGAP1	2.62e-05	279	158	11	PS50003
Domain	PH_domain	AGAP5 RALGPS2 DOCK10 ALS2 AGAP11 BCR PLEKHD1 CDC42BPB ARHGAP25 AGAP9 AGAP1	2.71e-05	280	158	11	IPR001849
Domain	S100A7	S100A7 S100A7A	7.11e-05	2	158	2	IPR028477
Domain	ArfGap	AGAP5 AGAP11 AGAP9 AGAP1	9.93e-05	29	158	4	SM00105
Domain	ARFGAP	AGAP5 AGAP11 AGAP9 AGAP1	9.93e-05	29	158	4	PS50115
Domain	ArfGap	AGAP5 AGAP11 AGAP9 AGAP1	9.93e-05	29	158	4	PF01412
Domain	ArfGAP	AGAP5 AGAP11 AGAP9 AGAP1	9.93e-05	29	158	4	IPR001164
Domain	cNMP	RAPGEF6 CNGA1 CNGA2 CNGA3	1.88e-04	34	158	4	SM00100
Domain	cNMP_binding	RAPGEF6 CNGA1 CNGA2 CNGA3	1.88e-04	34	158	4	PF00027
Domain	cNMP-bd_dom	RAPGEF6 CNGA1 CNGA2 CNGA3	2.10e-04	35	158	4	IPR000595
Domain	CNMP_BINDING_3	RAPGEF6 CNGA1 CNGA2 CNGA3	2.10e-04	35	158	4	PS50042
Domain	cNMP-bd-like	RAPGEF6 CNGA1 CNGA2 CNGA3	2.91e-04	38	158	4	IPR018490
Domain	cNMP-bd_CS	CNGA1 CNGA2 CNGA3	3.07e-04	16	158	3	IPR018488
Domain	-	LRP1 LRP2 LRP5 SORL1	3.22e-04	39	158	4	2.120.10.30
Domain	LDLR_class-A_CS	LRP1 LRP2 LRP5 SORL1	3.55e-04	40	158	4	IPR023415
Domain	Ldl_recept_a	LRP1 LRP2 LRP5 SORL1	5.61e-04	45	158	4	PF00057
Domain	6-blade_b-propeller_TolB-like	LRP1 LRP2 LRP5 SORL1	6.10e-04	46	158	4	IPR011042
Domain	-	LRP1 LRP2 LRP5 SORL1	6.10e-04	46	158	4	4.10.400.10
Domain	LDLRA_1	LRP1 LRP2 LRP5 SORL1	7.18e-04	48	158	4	PS01209
Domain	-	RAPGEF6 CNGA1 CNGA2 CNGA3	7.18e-04	48	158	4	2.60.120.10
Domain	PH	RALGPS2 DOCK10 AGAP11 BCR PLEKHD1 CDC42BPB ARHGAP25 AGAP1	7.53e-04	229	158	8	PF00169
Domain	LDrepeatLR_classA_rpt	LRP1 LRP2 LRP5 SORL1	7.77e-04	49	158	4	IPR002172
Domain	LDLa	LRP1 LRP2 LRP5 SORL1	7.77e-04	49	158	4	SM00192
Domain	LDLRA_2	LRP1 LRP2 LRP5 SORL1	7.77e-04	49	158	4	PS50068
Domain	RmlC-like_jellyroll	RAPGEF6 CNGA1 CNGA2 CNGA3	9.04e-04	51	158	4	IPR014710
Domain	-	AIFM1 AIFM3	1.45e-03	7	158	2	3.30.390.30
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	DMTF1 FAM184B USP45 ABCB7 RAPGEF6 FOXK2 GRWD1 DLGAP5 DDX42 RALGPS2 ALS2 GALNT7 ZFYVE1 FOXJ3 TRIP12 ALKBH8 CNOT6L WDHD1 SEC16A MASTL LRP2 ZMYM1 NFAT5 MFSD1 FAM135A CNOT2	4.16e-12	1084	158	26	11544199
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DCAF1 NPHP1 EYA4 ABCF1 FOXK2 RALGPS2 DVL3 BBS2 PRPF6 BCR FMNL2 CNOT6 WDR19 PPP1R7 CNOT6L DCP1B GLI3 SEC16A MARF1 PRMT1 NEURL4 CNOT2 AGAP1 SORL1 WDTC1	1.57e-09	1321	158	25	27173435
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AGAP5 RHOBTB3 DLGAP5 AGAP11 ADGRV1 ZFYVE1 BCR FOXJ3 CNOT6 WDR19 HECW2 TNRC6A ZBTB5 PCNX1 AGAP9 AGAP1	2.96e-09	529	158	16	14621295
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP5 AGAP11 AGAP9 AGAP1	5.08e-08	9	158	4	12640130
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	AGAP5 PPP1R13B AGAP11 ZFYVE1 VPS52 SLC25A13 TNRC6A HCFC2 AGAP9 AGAP1	6.79e-08	218	158	10	33378226
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	DCAF1 DDX42 PRPF6 CNOT6 PPP1R7 ZNF106 CNOT6L MAP1S AIFM1 TIPIN MASTL PPME1 SGO2 PRMT1 ZMYM1 ATM NEURL4 CNOT2 NXF1 MYBL1 WDTC1	7.13e-08	1155	158	21	20360068
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP5 AGAP11 AGAP9 AGAP1	8.43e-08	10	158	4	20664521
Pubmed	Expression of cyclic nucleotide-gated cation channels in non-sensory tissues and cells.	CNGA1 CNGA2 CNGA3	9.20e-08	3	158	3	7532814
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP5 AGAP11 AGAP9 AGAP1	1.32e-07	11	158	4	15381706
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP5 AGAP11 AGAP9 AGAP1	2.84e-07	13	158	4	27713690
Pubmed	Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.	LRP1 LRP2 LRP5	3.67e-07	4	158	3	7775583
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP5 AGAP11 AGAP9 AGAP1	3.96e-07	14	158	4	22453919
Pubmed	Genome-wide association study of antibody response to smallpox vaccine.	KIF6 PDYN BCR UNC13C PRKCQ	4.54e-07	34	158	5	22542470
Pubmed	GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets.	CNOT6 CNOT6L TNRC6A CNOT2	5.38e-07	15	158	4	21981923
Pubmed	Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.	LRP1 LRP2 SORL1	9.14e-07	5	158	3	19047013
Pubmed	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.	AGAP5 UBQLN1 AGAP11 WDR19 AIFM1 AGAP9 AGAP1	1.08e-06	116	158	7	30652415
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	DLGAP5 DDX42 BCR ZNF106 VPS52 POLR3B CNOT6L WDHD1 DCP1B SEC16A TNRC6A MASTL ZMYM1 USP54 CNOT2	1.42e-06	733	158	15	34672954
Pubmed	cGMP and cyclic nucleotide-gated channels participate in mouse sperm capacitation.	CNGA1 CNGA2 CNGA3	1.82e-06	6	158	3	22192355
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	GRWD1 DLGAP5 PPP1R13B CDC42BPB S100A7 PPP1R7 VPS52 MAP1S AIFM1 SLC25A13 SEC16A RBM7 PPME1	2.42e-06	573	158	13	28330616
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCAF1 RHOBTB3 ECT2L SCEL RFC5 BCR FMNL2 VPS52 GLI3 SLC25A13 SEC16A TNRC6A RBM7 LRP1 LRP2 USP54 SORL1 WDTC1	3.56e-06	1116	158	18	31753913
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ABCF1 UBQLN1 RHOBTB3 DVL3 FMNL2 TRIP12 CDC42BPB WDR19 POLR3B MAP1S LRP1 LRP2 ZBTB5 PPME1 ATM USP54 PBX3 CNOT2 AGAP1	6.52e-06	1285	158	19	35914814
Pubmed	Distinct expression patterns of the subunits of the CCR4-NOT deadenylase complex during neural development.	CNOT6 CNOT6L CNOT2	7.57e-06	9	158	3	21741365
Pubmed	Human transcription factor protein interaction networks.	EYA4 FOXK2 ARID4A PPP1R13B ARNT DCP1B AIFM1 GLI3 SLC25A13 SEC16A TNRC6A MARF1 LRP2 PRMT1 ZMYM1 USP54 HCFC2 CNOT2 NXF1 SORL1	8.21e-06	1429	158	20	35140242
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ABCB7 ARID4A SLC34A3 VSIG10 ZNF106 PTPN11 ARNT VPS52 ALKBH8 AIFM1 GLI3 SLC25A13 SEC16A RBM7 PPME1 PRMT1 HCFC2 CNOT2 NXF1	1.02e-05	1327	158	19	32694731
Pubmed	International Union of Pharmacology. LI. Nomenclature and structure-function relationships of cyclic nucleotide-regulated channels.	CNGA1 CNGA2 CNGA3	1.08e-05	10	158	3	16382102
Pubmed	miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.	CNOT6L TNRC6A CNOT2	1.08e-05	10	158	3	21984185
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ABCF1 RAPGEF6 ARID4A DLGAP5 TRIP12 HNRNPC ZNF551 ZNF106 MAP1S WDHD1 SEC16A RBM7 UTP20 ATM	1.30e-05	774	158	14	15302935
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP1 LRP2 LRP5	1.48e-05	11	158	3	24639464
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	AGAP5 ARID4A RHOBTB3 DDX42 RALGPS2 AGAP11 ELAC2 PLIN2 CNOT6 ZNF106 HECW2 ATXN3 SGO2 PRMT1 ARHGAP25 AGAP9 AGAP1 WDTC1	1.52e-05	1242	158	18	30973865
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ABCF1 FOXK2 UBQLN1 GRWD1 RAB11A ECT2L RFC5 FOXJ3 CDC42BPB CNOT6 CNOT6L SLC25A13 TNRC6A RBM7 UTP20 PRMT1 HCFC2 CNOT2 NXF1 AGAP1	1.61e-05	1497	158	20	31527615
Pubmed	Functional proteomics mapping of a human signaling pathway.	DMTF1 UBQLN1 DVL3 PPP1R13B FMNL2 TRIP12 RYR2 ZNF106 ARNT DCP1B LRP1 LRP5	1.80e-05	591	158	12	15231748
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NRG1 FLT1 ABCF1 PRPF6 RFC5 TRIP12 ZNF106 MAP1S SLC25A13 ATM GOLGA1	1.85e-05	497	158	11	36774506
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	ABCF1 DDX42 DVL3 PRPF6 TRIP12 CDC42BPB HNRNPC VPS52 MAP1S SEC16A NXF1	1.89e-05	498	158	11	36634849
Pubmed	Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth.	CNOT6 CNOT6L CNOT2	1.96e-05	12	158	3	17452450
Pubmed	Human Ccr4-Not complexes contain variable deadenylase subunits.	CNOT6 CNOT6L CNOT2	1.96e-05	12	158	3	19558367
Pubmed	Reconstitution of recombinant human CCR4-NOT reveals molecular insights into regulated deadenylation.	CNOT6 CNOT6L CNOT2	1.96e-05	12	158	3	31320642
Pubmed	Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain.	PTPN11 LRP1	2.05e-05	2	158	2	18381291
Pubmed	Adipocyte differentiation-related protein is induced by LRP1-mediated aggregated LDL internalization in human vascular smooth muscle cells and macrophages.	PLIN2 LRP1	2.05e-05	2	158	2	17620659
Pubmed	CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.	CNOT6 CNOT6L	2.05e-05	2	158	2	34788619
Pubmed	Hypoxia-inducible factor-1β is essential for upregulation of the hypoxia-induced FLT1 gene in placental trophoblasts.	FLT1 ARNT	2.05e-05	2	158	2	34665260
Pubmed	Ataxia telangiectasia-mutated, a DNA damage-inducible kinase, contributes to high NaCl-induced nuclear localization of transcription factor TonEBP/OREBP.	ATM NFAT5	2.05e-05	2	158	2	15840767
Pubmed	Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.	LRP1 LRP2	2.05e-05	2	158	2	34445520
Pubmed	Syp Y279, Y304 Can Mediate the Binding of Bcr-Abl to Grb2 and Other Proteins.	BCR PTPN11	2.05e-05	2	158	2	12115002
Pubmed	ATM, a DNA damage-inducible kinase, contributes to activation by high NaCl of the transcription factor TonEBP/OREBP.	ATM NFAT5	2.05e-05	2	158	2	15173573
Pubmed	The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence.	CNOT6 CNOT6L	2.05e-05	2	158	2	21233283
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	ABCF1 RAPGEF6 FOXK2 GRWD1 DVL3 ZFYVE1 BCR HNRNPC S100A7 VPS52 WDHD1 DCP1B SEC16A CNOT2 AGAP1 WDTC1	2.22e-05	1038	158	16	26673895
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DMTF1 RAPGEF6 UBQLN1 FOXJ3 TRIP12 HNRNPC MAP1S ZMYM1 ATM NEURL4	2.96e-05	430	158	10	35044719
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	NEXMIF FMNL2 TRIP12 IGSF10 PPP1R7 AIFM1 HECW2 SCN3A LRP2 UTP20 ATM NXF1 GP5	3.43e-05	736	158	13	29676528
Pubmed	LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.	RAB11A GLI3 LRP2	4.02e-05	15	158	3	22340494
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DCAF1 ABCF1 DLGAP5 DOCK10 PRPF6 RFC5 TRIP12 HNRNPC ELAC2 S100A7 POLR3B AIFM1 SLC25A13 SEC16A RBM7 UTP20 PRMT1 NXF1	4.64e-05	1353	158	18	29467282
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	UBQLN1 ALS2 RFC5 TRIP12 RSU1 SEC16A ATXN3 CNOT2	5.53e-05	288	158	8	23383273
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	RAB11A FMNL2 TRIP12 PKHD1L1 CDC42BPB RYR2 VPS52 GLI3 SEC16A TNRC6A HCFC2 FAM135A AGAP1	5.94e-05	777	158	13	35844135
Pubmed	The mouse S100A15 ortholog parallels genomic organization, structure, gene expression, and protein-processing pattern of the human S100A7/A15 subfamily during epidermal maturation.	S100A7 S100A7A	6.13e-05	3	158	2	16528363
Pubmed	Activated α2-macroglobulin induces Müller glial cell migration by regulating MT1-MMP activity through LRP1.	RAB11A LRP1	6.13e-05	3	158	2	23640058
Pubmed	Hepatic posttranscriptional network comprised of CCR4-NOT deadenylase and FGF21 maintains systemic metabolic homeostasis.	CNOT6 CNOT6L	6.13e-05	3	158	2	30926667
Pubmed	Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors.	FOXK2 FOXJ3	6.13e-05	3	158	2	26578569
Pubmed	Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.	BCR PTPN11	6.13e-05	3	158	2	23980151
Pubmed	CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte.	CNOT6 CNOT6L	6.13e-05	3	158	2	30478191
Pubmed	S100A7 enhances mammary tumorigenesis through upregulation of inflammatory pathways.	S100A7 S100A7A	6.13e-05	3	158	2	22158945
Pubmed	Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.	LRP1 SORL1	6.13e-05	3	158	2	28799085
Pubmed	Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7.	S100A7 S100A7A	6.13e-05	3	158	2	37769710
Pubmed	FOXK2 transcriptionally activating VEGFA induces apatinib resistance in anaplastic thyroid cancer through VEGFA/VEGFR1 pathway.	FLT1 FOXK2	6.13e-05	3	158	2	34489549
Pubmed	SH2-containing phosphotyrosine phosphatase Syp is a target of p210bcr-abl tyrosine kinase.	BCR PTPN11	6.13e-05	3	158	2	8195176
Pubmed	Elevated Expression of Hepatoma Up-Regulated Protein Inhibits γ-Irradiation-Induced Apoptosis of Prostate Cancer Cells.	DLGAP5 ATM	6.13e-05	3	158	2	26505164
Pubmed	mda-7/IL-24 Induces Cell Death in Neuroblastoma through a Novel Mechanism Involving AIF and ATM.	AIFM1 ATM	6.13e-05	3	158	2	27197168
Pubmed	Functional activity of photoreceptor cyclic nucleotide-gated channels is dependent on the integrity of cholesterol- and sphingolipid-enriched membrane domains.	CNGA1 CNGA3	6.13e-05	3	158	2	18303857
Pubmed	Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis.	S100A7 S100A7A	6.13e-05	3	158	2	15717926
Pubmed	Ryanodine Receptor 2 Contributes to Impaired Protein Localization in Cyclic Nucleotide-Gated Channel Deficiency.	RYR2 CNGA3	6.13e-05	3	158	2	31182474
Pubmed	The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events.	PTPN11 LRP1	6.13e-05	3	158	2	23922991
Pubmed	Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.	LRP1 PLCE1	6.13e-05	3	158	2	27322543
Pubmed	LMKB/MARF1 localizes to mRNA processing bodies, interacts with Ge-1, and regulates IFI44L gene expression.	MARF1 IFI44L	6.13e-05	3	158	2	24755989
Pubmed	Importance of the CNGA4 channel gene for odor discrimination and adaptation in behaving mice.	CNGA1 CNGA2	6.13e-05	3	158	2	12649326
Pubmed	Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.	SCN3A LRP1 LRP2	7.14e-05	18	158	3	10827173
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	DCAF1 ABCB7 UBQLN1 RFC5 BCR TRIP12 ELAC2 LRP1 SGO2 PRMT1 CNOT2 AGAP1	7.58e-05	686	158	12	28380382
Pubmed	Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.	GRWD1 AGAP11 ADGRV1 TMEM132D	8.68e-05	51	158	4	11853319
Pubmed	Large-scale analysis of the human ubiquitin-related proteome.	EMC3 UBQLN1 GRWD1 RFC5 HNRNPC SLC25A13 TNRC6A ATXN3	9.85e-05	313	158	8	16196087
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	DCAF1 RHOBTB3 BCR FMNL2 WDHD1 HECW2 ATM NEURL4	9.85e-05	313	158	8	38270169
Pubmed	RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation.	CNOT6 CNOT6L CNOT2	9.91e-05	20	158	3	34887419
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	NPHP1 BBS2 PTPN11 LRP2 LRP5 PRKCQ CNGA3	1.00e-04	233	158	7	32290105
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	FLT1 ADGRV1 BCR LRP1 LRP2	1.01e-04	101	158	5	23382219
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ABCF1 GRWD1 DVL3 PRPF6 RFC5 TRIP12 HNRNPC VPS52 FAM111A AIFM1 SLC25A13 SEC16A TNRC6A PPME1 PRMT1 PRKCQ NXF1	1.11e-04	1318	158	17	30463901
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1 LRP2 LRP5	1.15e-04	21	158	3	21337463
Pubmed	Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.	LRP1 LRP2	1.22e-04	4	158	2	12413896
Pubmed	Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity.	S100A7 S100A7A	1.22e-04	4	158	2	18223693
Pubmed	The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation.	UBQLN1 BCR	1.22e-04	4	158	2	22451666
Pubmed	Odorant receptors govern the formation of a precise topographic map.	OR1E1 OR1E2	1.22e-04	4	158	2	9546391
Pubmed	CLEC12B Decreases Melanoma Proliferation by Repressing Signal Transducer and Activator of Transcription 3.	PTPN11 CLEC12B	1.22e-04	4	158	2	34310951
Pubmed	Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1.	CNGA1 CNGA3	1.22e-04	4	158	2	15634774
Pubmed	Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure.	CNOT6 CNOT6L	1.22e-04	4	158	2	35385705
Pubmed	Loss of CNGB1 protein leads to olfactory dysfunction and subciliary cyclic nucleotide-gated channel trapping.	CNGA2 CNGA3	1.22e-04	4	158	2	16980309
Pubmed	Reactive oxygen species regulation by AIF- and complex I-depleted brain mitochondria.	AIFM1 AIFM3	1.22e-04	4	158	2	19280713
Pubmed	Molecular cloning and characterization of alternatively spliced mRNA isoforms from psoriatic skin encoding a novel member of the S100 family.	S100A7 S100A7A	1.22e-04	4	158	2	12923069
Pubmed	NFAR-1 and -2 modulate translation and are required for efficient host defense.	HNRNPC NXF1	1.22e-04	4	158	2	18337511
Pubmed	Tyrosine 1213 of Flt-1 is a major binding site of Nck and SHP-2.	FLT1 PTPN11	1.22e-04	4	158	2	9600074
Pubmed	Potential contribution of ryanodine receptor 2 upregulation to cGMP/PKG signaling-induced cone degeneration in cyclic nucleotide-gated channel deficiency.	RYR2 CNGA3	1.22e-04	4	158	2	32173907
Pubmed	Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.	LRP1 LRP2	1.22e-04	4	158	2	11421580
Pubmed	Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15.	S100A7 S100A7A	1.22e-04	4	158	2	18606705
Pubmed	The pro-neurotrophin receptor sortilin is a major neuronal apolipoprotein E receptor for catabolism of amyloid-β peptide in the brain.	LRP1 SORL1	1.22e-04	4	158	2	23283348
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	DCAF1 PPP1R7 ZNF106 VPS52 TNRC6A ATXN3 NXF1	1.27e-04	242	158	7	34011540
Pubmed	Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.	CNOT6 CNOT6L CNOT2	1.33e-04	22	158	3	18377426
Interaction	CEP85 interactions	EYA4 HNRNPC CNOT6L GLI3 SEC16A TNRC6A MARF1 MASTL CNOT2 NXF1	7.59e-07	169	155	10	int:CEP85
Interaction	TNRC6B interactions	NPHP1 EYA4 CNOT6 CNOT6L DCP1B GLI3 SEC16A TNRC6A MARF1 USP54 CNOT2 NXF1	1.96e-06	282	155	12	int:TNRC6B
Interaction	MEX3B interactions	DVL3 PPP1R13B CNOT6L DCP1B SEC16A TNRC6A MARF1 PRMT1 USP54 CNOT2	8.77e-06	222	155	10	int:MEX3B
Interaction	ZFP36 interactions	PPP1R13B CNOT6 CNOT6L DCP1B SEC16A TNRC6A MARF1 USP54 CNOT2	1.14e-05	181	155	9	int:ZFP36
Interaction	CNOT7 interactions	DVL3 BBS2 CNOT6 CNOT6L TNRC6A HCFC2 CNOT2 WDTC1	1.29e-05	140	155	8	int:CNOT7
Interaction	FAM120C interactions	DVL3 PPP1R13B HNRNPC SEC16A TNRC6A MARF1 PRMT1 USP54 CNOT2	1.75e-05	191	155	9	int:FAM120C
Interaction	DKK2 interactions	ARID4A S100A7 LRP2 LRP5 SORL1	3.66e-05	49	155	5	int:DKK2
Interaction	GARRE1 interactions	EYA4 CNOT6 CNOT6L DCP1B SEC16A TNRC6A USP54 CNOT2	4.60e-05	167	155	8	int:GARRE1
Interaction	S100A7L2 interactions	S100A7 S100A7A PPME1	5.15e-05	10	155	3	int:S100A7L2
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP5 AGAP11 AGAP9 AGAP1	3.35e-06	17	114	4	1291
GeneFamily	Cyclic nucleotide gated channels	CNGA1 CNGA2 CNGA3	2.84e-05	10	114	3	250
GeneFamily	CCR4-NOT transcription complex	CNOT6 CNOT6L CNOT2	3.88e-05	11	114	3	1023
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AGAP5 RALGPS2 DOCK10 BCR PLEKHD1 ARHGAP25 AGAP9 AGAP1	4.86e-05	206	114	8	682
GeneFamily	ArfGAPs	AGAP5 AGAP11 AGAP9 AGAP1	5.33e-05	33	114	4	395
GeneFamily	Low density lipoprotein receptors	LRP1 LRP2 LRP5	6.67e-05	13	114	3	634
GeneFamily	Collagens\|Collagen proteoglycans	COL12A1 COL15A1	3.89e-04	5	114	2	575
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	NRG1 FLT1 VSIG10 ADAMTSL3 IGSF10	3.54e-03	161	114	5	593
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	DMTF1 ARID4A DDX42 TNRC6A PBX3 NFAT5 GOLGA1 DISP1 NXF1	7.90e-07	166	158	9	M6826
Coexpression	GSE13306_RA_VS_UNTREATED_TREG_UP	BBS2 RSU1 ARNT ALKBH8 WDHD1 TNRC6A RAB2B UTP20 ZMYM1	3.69e-06	200	158	9	M3232
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#1_top-relative-expression-ranked_1000	ARID4A DOCK10 FOXJ3 TRIP12 CNOT6L FAM111A HECW2 GLI3 SGO2 HCFC2 FAM135A ARMH4	9.54e-06	349	154	12	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k1_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#3_top-relative-expression-ranked_1000	EYA4 COL12A1 ARID4A RHOBTB3 DOCK10 TRIP12 CNOT6L FAM111A SGO2 HCFC2 FAM135A	1.55e-05	307	154	11	gudmap_developingKidney_e15.5_Peripheral blastema_1000_k3
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	ADGRG5 DOCK10 CNOT6L PCNX1 ARHGAP25 PRKCQ ATM MYBL1 SORL1	2.54e-08	187	159	9	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B ABCA13 ADGRV1 PKHD1L1 RYR2 SCN3A LRP2 UNC13C	1.76e-07	169	159	8	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA13 ADGRV1 PKHD1L1 RYR2 LRP2 UNC13C PLCE1	3.36e-07	184	159	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA13 ADGRV1 PKHD1L1 RYR2 LRP2 UNC13C PLCE1	3.36e-07	184	159	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 ABCA13 ADGRV1 PKHD1L1 RYR2 LRP2 UNC13C PLCE1	3.36e-07	184	159	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NRG1 EYA4 PDYN PLIN2 SLC25A13 UNC13C PRKCQ	3.58e-07	126	159	7	94bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 ABCA13 LAMA2 ADAMTSL3 PKHD1L1 IGSF10 GLI3 LRP2	3.80e-07	187	159	8	4e553721fa5598cb211f44e3226280b7e6885484
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 ABCA13 LAMA2 ADAMTSL3 PKHD1L1 IGSF10 GLI3 LRP2	3.80e-07	187	159	8	d36e7fc6125e7a4310499365022d38f34b757a73
ToppCell	droplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 ABCA13 LAMA2 ADAMTSL3 PKHD1L1 IGSF10 GLI3 LRP2	3.80e-07	187	159	8	827eae63fabf6892a82ce7779b5f395958d3d628
ToppCell	COVID-19-Heart-T_cell\|Heart / Disease (COVID-19 only), tissue and cell type	ADGRG5 NRG1 ABCA13 DOCK10 TMEM132D PRKCQ MYBL1 SORL1	4.29e-07	190	159	8	e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP45 TRARG1 DOCK10 ADGRV1 ALKBH8 ARMH4 SORL1	1.71e-06	159	159	7	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	AT1_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	NRG1 EYA4 COL12A1 SCEL HHLA2 TMEM132D PLCE1	1.94e-06	162	159	7	ae2ba4f21f6f6c512006fa531d670b88be7c04c9
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCR FMNL2 PKHD1L1 S100A7A SCN3A NFAT5 PLCE1	2.11e-06	164	159	7	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCR FMNL2 PKHD1L1 S100A7A SCN3A NFAT5 PLCE1	2.11e-06	164	159	7	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCR FMNL2 PKHD1L1 S100A7A SCN3A NFAT5 PLCE1	2.11e-06	164	159	7	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCR FMNL2 PKHD1L1 S100A7A SCN3A NFAT5 PLCE1	2.11e-06	164	159	7	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	NRG1 EYA4 COL12A1 ADGRV1 SCEL PNRC1 USP54	2.67e-06	170	159	7	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 RALGPS2 LAMA2 ADGRV1 RYR2 LRP2 FCAMR	3.24e-06	175	159	7	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 RALGPS2 LAMA2 ADGRV1 RYR2 LRP2 FCAMR	3.36e-06	176	159	7	c6484334187f64cd00cd35e77d8ae436556b4260
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KIF6 SLC34A3 ADGRV1 ITGAD ADAMTSL3 TMEM125	3.63e-06	115	159	6	15b2c11225802cc15c01165d84a755432f02d82f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 NEXMIF RHOBTB3 GALNT7 SCN3A UNC13C CNGA1	3.76e-06	179	159	7	d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCell	COVID-19-kidney-NK\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADGRG5 DOCK10 CNOT6L PRKCQ ATM MYBL1 SORL1	4.05e-06	181	159	7	8906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	ADGRG5 DOCK10 CNOT6L ARHGAP25 PRKCQ ATM MYBL1	4.67e-06	185	159	7	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	Control-T_cells-NK_cells\|Control / group, cell type (main and fine annotations)	ADGRG5 DOCK10 CNOT6L PRKCQ ATM MYBL1 SORL1	4.67e-06	185	159	7	755c0998c729f462399f1d5e88adf4bfae31be30
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 CNOT6L ARHGAP25 PRKCQ ATM MYBL1 SORL1	4.84e-06	186	159	7	9d576dce2c5deefef1adda16c6da7055c8d57f8f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 CNOT6L ARHGAP25 PRKCQ ATM MYBL1 SORL1	4.84e-06	186	159	7	bd3bd022b575d9b0ef90d50a5cb874085a827b77
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 CNOT6L ARHGAP25 PRKCQ ATM MYBL1 SORL1	4.84e-06	186	159	7	924cc357b4c4ce8e9b05773bdab544f0b65474cc
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DLGAP5 ADGRV1 FAM111A LRP2 SGO2 TMEM125 MYBL1	5.38e-06	189	159	7	c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DMTF1 ADGRG5 DOCK10 ARHGAP25 PRKCQ ATM MYBL1	5.57e-06	190	159	7	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	EYA4 COL12A1 SYN3 RHOBTB3 DOCK10 VSIG10 UNC13C	5.96e-06	192	159	7	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FLT1 COL12A1 COL15A1 LAMA2 ADAMTSL3 LRP1 AGAP1	5.96e-06	192	159	7	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	COVID-19-lung-NK/NKT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADGRG5 DOCK10 CNOT6L PRKCQ ATM MYBL1 SORL1	6.17e-06	193	159	7	c24b44fcc92fff42ebba6f1aff91c7aaea179e56
ToppCell	COVID-19-lung-NK/NKT\|lung / Disease (COVID-19 only), tissue and cell type	ADGRG5 DOCK10 CNOT6L PRKCQ ATM MYBL1 SORL1	6.60e-06	195	159	7	3ab941a369e3815f338890b116dc77aefa054098
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 TRARG1 LAMA2 ADAMTSL3 IGSF10 LRP1 LRP2	6.82e-06	196	159	7	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL15A1 TRARG1 LAMA2 ADAMTSL3 IGSF10 LRP1 LRP2	6.82e-06	196	159	7	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRG5 DOCK10 ITGAD CNOT6L ATM MYBL1 SORL1	7.78e-06	200	159	7	d2422aaf807010194994db97142b9fd2e807312d
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADGRG5 DOCK10 ITGAD CNOT6L ATM MYBL1 SORL1	7.78e-06	200	159	7	1d2ee63010b7b8b38bea7d3b30eebfbcdd18b967
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 UNC13C TMEM125 CNGA1 FAM135A CNGA2	2.23e-05	158	159	6	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 UNC13C TMEM125 CNGA1 FAM135A CNGA2	2.23e-05	158	159	6	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 LAMA2 ADGRV1 PKHD1L1 RYR2 LRP2	2.40e-05	160	159	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 LAMA2 ADGRV1 PKHD1L1 RYR2 LRP2	2.40e-05	160	159	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB11A BCR PKHD1L1 SCN3A NFAT5 PLCE1	2.48e-05	161	159	6	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB11A BCR PKHD1L1 SCN3A NFAT5 PLCE1	2.48e-05	161	159	6	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB11A BCR PKHD1L1 SCN3A NFAT5 PLCE1	2.48e-05	161	159	6	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABCA13 MYT1 ADGRV1 PKHD1L1 AIFM3 CNGA1	2.57e-05	162	159	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RAPGEF6 DOCK10 NT5C1B CNOT6L PCNX1 ATM	2.57e-05	162	159	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAB11A BCR PKHD1L1 SCN3A NFAT5 PLCE1	2.57e-05	162	159	6	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	DCAF1 FOXJ3 WDR19 POLR3B MAML3 WDTC1	2.95e-05	166	159	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	droplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP5 PPP1R13B ZFYVE1 ZBTB5 HCFC2 CLEC12B	3.48e-05	171	159	6	e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	COL12A1 RHOBTB3 SCEL KRT71 SCN3A LRP5	3.60e-05	172	159	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	droplet-Heart-HEART-1m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGPS2 BCR PKHD1L1 POLR3B SCN3A PRKCQ	3.72e-05	173	159	6	9dc7746a84f0e268a7c061e1bbcd5e31903034dc
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK10 ITGAD WDR19 POLR3B ATM MYBL1	3.72e-05	173	159	6	79d11f94a8f6a420c18c2fef0da77e9af3204765
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	NRG1 EYA4 COL12A1 SCEL TMEM132D PLCE1	3.84e-05	174	159	6	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 SYN3 LAMA2 IGSF10 LRP1	4.09e-05	176	159	6	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 SYN3 LAMA2 IGSF10 LRP1	4.09e-05	176	159	6	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5\|TCGA-Skin / Sample_Type by Project: Shred V9	FLT1 COL12A1 RTL5 MYT1 HECW2 PLCE1	4.36e-05	178	159	6	ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell	LA-17._Lymphocyte\|World / Chamber and Cluster_Paper	DOCK10 CNOT6L ARHGAP25 PRKCQ MYBL1 SORL1	4.36e-05	178	159	6	34ec499d03cc198cfefa19a724d4c81974052f65
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD6 DLGAP5 PLEKHD1 ALKBH8 SGO2 MYBL1	4.50e-05	179	159	6	4166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCell	LA-17._Lymphocyte\|LA / Chamber and Cluster_Paper	DOCK10 CNOT6L ARHGAP25 PRKCQ MYBL1 SORL1	4.78e-05	181	159	6	3fd9f805fa46141b0fa7023ee5d8688d338635d5
ToppCell	RA-17._Lymphocyte\|RA / Chamber and Cluster_Paper	DOCK10 CNOT6L ARHGAP25 PRKCQ MYBL1 SORL1	4.93e-05	182	159	6	257a7847917b6ea1d60608183d90300bfd028758
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NRG1 EYA4 COL12A1 FMNL2 RYR2 PBX3	4.93e-05	182	159	6	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B KIF6 XIRP1 TRARG1 SCN3A PLCE1	5.08e-05	183	159	6	421265fa15d5a028cb567bb0904e670473ef102b
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	EYA4 COL12A1 RHOBTB3 SCEL USP54 PLCE1	5.08e-05	183	159	6	6821dca076318115d360ff426eb1218cfe104063
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM184B KIF6 XIRP1 TRARG1 SCN3A PLCE1	5.08e-05	183	159	6	8d45dff06a199b1369576657f7f9dc0249c5f841
ToppCell	RA-17._Lymphocyte\|World / Chamber and Cluster_Paper	DOCK10 CNOT6L ARHGAP25 PRKCQ MYBL1 SORL1	5.08e-05	183	159	6	6397f684a50346fc42cccb5afbe10350f4b2d9b0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PPP1R13B ADGRV1 TMEM132D UNC13C USP54 AGAP1	5.24e-05	184	159	6	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIF6 ABCA13 C1orf87 ECT2L HHLA2 LRRC74B	5.24e-05	184	159	6	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RAPGEF6 CNOT6L TNRC6A PRKCQ ATM SORL1	5.24e-05	184	159	6	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	NPHP1 KIF6 ABCA13 C1orf87 ECT2L HHLA2	5.40e-05	185	159	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 CDC42BPB HECW2 AIFM3 ZBTB5 ZMYM1	5.56e-05	186	159	6	37860daeecd6d412bd3797f30496a56da667fbd1
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 CDC42BPB HECW2 AIFM3 ZBTB5 ZMYM1	5.56e-05	186	159	6	60830822d3de3147816693404fd03392e04c2b8e
ToppCell	droplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FMNL2 CDC42BPB HECW2 AIFM3 ZBTB5 ZMYM1	5.56e-05	186	159	6	baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 PPP1R13B TMEM132D GLI3 PRKCQ PBX3	5.56e-05	186	159	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Nrip3_(CA1_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	NT5C1B OLIG3 ACKR2 FCAMR	5.88e-05	59	159	4	172f1c6fdc8005a6f21d68a4dc0f8631c265d9e5
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	KIF6 ABCA13 C1orf87 ECT2L HHLA2 LRRC74B	5.90e-05	188	159	6	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Fetal_29-31_weeks-Immune-natural_killer_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADGRG5 CNOT6L PRKCQ ATM MYBL1 SORL1	5.90e-05	188	159	6	1082861eb9e00409caa06d8b2a7b8e7f5fac94c9
ToppCell	COPD-Lymphoid-NK\|COPD / Disease state, Lineage and Cell class	ADGRG5 BCR CNOT6L PRKCQ MYBL1 SORL1	5.90e-05	188	159	6	c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	KIF6 ABCA13 C1orf87 ECT2L HHLA2 LRRC74B	5.90e-05	188	159	6	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIF6 ABCA13 C1orf87 ECT2L HHLA2 LRRC74B	5.90e-05	188	159	6	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	KIF6 ABCA13 C1orf87 ECT2L HHLA2 LRRC74B	6.08e-05	189	159	6	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	KIF6 ABCA13 C1orf87 ECT2L HHLA2 LRRC74B	6.08e-05	189	159	6	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	NRG1 EYA4 COL12A1 RHOBTB3 SCEL PLCE1	6.08e-05	189	159	6	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	COPD-Lymphoid-NK\|World / Disease state, Lineage and Cell class	ADGRG5 BCR CNOT6L PRKCQ MYBL1 SORL1	6.08e-05	189	159	6	c0ac160fa7e68b92414fb1600abcac8ad1a42232
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	KIF6 ABCA13 C1orf87 ECT2L HHLA2 LRRC74B	6.08e-05	189	159	6	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-T_cells-NK_cells\|COVID-19 / group, cell type (main and fine annotations)	ADGRG5 DOCK10 CNOT6L PRKCQ MYBL1 SORL1	6.08e-05	189	159	6	b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 LAMA2 ADAMTSL3 GLI3 LRP1	6.26e-05	190	159	6	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	COVID-19-kidney-NK\|kidney / Disease (COVID-19 only), tissue and cell type	ADGRG5 DOCK10 CNOT6L PRKCQ ATM MYBL1	6.26e-05	190	159	6	e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 EYA4 COL15A1 LAMA2 ADAMTSL3 RYR2	6.26e-05	190	159	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	DOCK10 CNOT6L PCNX1 ARHGAP25 PRKCQ MYBL1	6.26e-05	190	159	6	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 PCNX1 ARHGAP25 PRKCQ MYBL1 SORL1	6.44e-05	191	159	6	d9506b88d806aadd4c2b9bf86fe994c47799e7f6
ToppCell	10x5'v1-week_14-16-Hematopoietic-MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PKHD1L1 RSU1 RYR2 IGSF10 PRKCQ GP5	6.44e-05	191	159	6	7edc22e7e70697fb22690699efb352577162709b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 PCNX1 ARHGAP25 PRKCQ MYBL1 SORL1	6.44e-05	191	159	6	9aabbc65430e2233b8f2d3fff9face7807b88b48
ToppCell	IPF-Lymphoid-NK\|World / Disease state, Lineage and Cell class	ADGRG5 CNOT6L PRKCQ ATM MYBL1 SORL1	6.44e-05	191	159	6	f206159b9d5e84cf14a65bfdc008895cec5a8081
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-T_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 PCNX1 ARHGAP25 PRKCQ MYBL1 SORL1	6.44e-05	191	159	6	b42c54308abe1241cc38ddce96b9d38d07983891
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL15A1 LAMA2 ADAMTSL3 FMNL2 SLC25A13 ATXN3	6.44e-05	191	159	6	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL12A1 COL15A1 LAMA2 ADAMTSL3 GLI3 LRP1	6.63e-05	192	159	6	5105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EYA4 COL15A1 RHOBTB3 ADAMTSL3 IFI44L PBX3	6.63e-05	192	159	6	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RAPGEF6 DOCK10 CNOT6L PCNX1 ATM SORL1	6.63e-05	192	159	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Immune-natural_killer_cell\|World / Lineage, Cell type, age group and donor	ADGRG5 CNOT6L PRKCQ ATM MYBL1 SORL1	6.63e-05	192	159	6	68121a6ef4115a93d87aad8802ef9b27d793d8c0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL15A1 SYN3 LAMA2 IGSF10 LRP1 ARMH4	6.63e-05	192	159	6	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
Disease	cerebral palsy (implicated_via_orthology)	AGAP5 AGAP11 AGAP9 AGAP1	1.39e-07	10	152	4	DOID:1969 (implicated_via_orthology)
Disease	vital capacity	FAM184B NRG1 FLT1 EYA4 MYT1 MFSD6 RALGPS2 LAMA2 ADAMTSL3 TRIP12 HNRNPC RYR2 ZNF106 OLIG3 AIFM1 GLI3 ATXN3 LRP2 NFAT5 AGAP1 PLCE1	1.59e-06	1236	152	21	EFO_0004312
Disease	response to vaccine	KIF6 BCR HNRNPC UNC13C PRKCQ IFI44L	4.18e-05	122	152	6	EFO_0004645
Disease	Disorder of eye	NPHP1 BBS2 PRPF6 ADGRV1 LRP5 CNGA1 CNGA3	1.20e-04	212	152	7	C0015397
Disease	Transitional cell carcinoma of bladder	FLT1 BCR	1.57e-04	4	152	2	C0279680
Disease	cortical thickness	KIF6 EYA4 COL12A1 RALGPS2 LAMA2 ADGRV1 ADAMTSL3 FMNL2 ELAC2 ZNF106 GLI3 SPATA16 TNRC6A LRP1 AGAP1 PLCE1	2.12e-04	1113	152	16	EFO_0004840
Disease	Malignant neoplasm of breast	NRG1 FLT1 KIF6 XIRP1 C1orf87 DVL3 LAMA2 PLEKHD1 ALKBH8 UTP20 ATM USP54 TMEM125 CNGA2 SORL1	4.54e-04	1074	152	15	C0006142
Disease	amyotrophic lateral sclerosis (implicated_via_orthology)	UBQLN1 ALS2 ZNF106	4.91e-04	30	152	3	DOID:332 (implicated_via_orthology)
Disease	asthma	DCAF1 EYA4 RAPGEF6 COL15A1 MYT1 ADAMTSL3 FMNL2 TMEM132D GLI3 LRP1 UNC13C PRKCQ	5.37e-04	751	152	12	MONDO_0004979
Disease	Nephronophthisis, familial juvenile	NPHP1 WDR19	5.44e-04	7	152	2	C1855681
Disease	Senior-Loken syndrome (is_implicated_in)	NPHP1 WDR19	5.44e-04	7	152	2	DOID:0050576 (is_implicated_in)
Disease	Renal dysplasia and retinal aplasia	NPHP1 WDR19	5.44e-04	7	152	2	cv:C0403553
Disease	cortical surface area measurement	KIF6 MYT1 RALGPS2 DOCK10 LAMA2 ADGRV1 ADAMTSL3 BCR FMNL2 ELAC2 CNOT6 ZNF106 GLI3 SPATA16 TNRC6A AGAP1 PLCE1	5.89e-04	1345	152	17	EFO_0010736
Disease	Chronic pain	EYA4 PRKCQ	7.23e-04	8	152	2	HP_0012532
Disease	Retinal Pigment Epithelial Detachment	AIFM1 PRKCQ	9.27e-04	9	152	2	C0339546
Disease	heart disease (implicated_via_orthology)	RYR2 CNOT6 CNOT6L	9.91e-04	38	152	3	DOID:114 (implicated_via_orthology)
Disease	orofacial cleft, sex interaction measurement	KIF6 COL12A1 AGAP1 PLCE1	1.04e-03	86	152	4	EFO_0008343, MONDO_0000358
Disease	mitochondrial complex I deficiency (implicated_via_orthology)	ELAC2 AIFM1	1.15e-03	10	152	2	DOID:0060536 (implicated_via_orthology)
Disease	Neurodevelopmental Disorders	NEXMIF TRIP12 CDC42BPB PTPN11	1.38e-03	93	152	4	C1535926
Disease	Retinal Detachment	AIFM1 PRKCQ	1.41e-03	11	152	2	C0035305
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 PLCE1	1.41e-03	11	152	2	DOID:3717 (is_implicated_in)
Disease	alcohol use disorder measurement, alcohol consumption measurement	GALNT7 TNRC6A ARMH4 SORL1	1.62e-03	97	152	4	EFO_0007878, EFO_0009458
Disease	Renal dysplasia and retinal aplasia (disorder)	NPHP1 WDR19	1.68e-03	12	152	2	C0403553
Disease	Charcot-Marie-Tooth disease (is_implicated_in)	NRG1 POLR3B	1.68e-03	12	152	2	DOID:10595 (is_implicated_in)
Disease	tyrosine-protein phosphatase non-receptor type 1 measurement	PDYN HNRNPC	1.98e-03	13	152	2	EFO_0020834
Disease	Nephronophthisis	NPHP1 WDR19	1.98e-03	13	152	2	C0687120
Disease	body weight	DMTF1 NRG1 EMC3 NEXMIF BBS2 ADGRV1 RFC5 ADAMTSL3 ZFYVE1 TRIP12 RSU1 HHLA2 TNRC6A MAML3 AGAP1	2.25e-03	1261	152	15	EFO_0004338
Disease	Bardet-Biedl syndrome (is_implicated_in)	NPHP1 BBS2	2.30e-03	14	152	2	DOID:1935 (is_implicated_in)
Disease	Ciliopathies	NPHP1 BBS2 ADGRV1 WDR19	2.56e-03	110	152	4	C4277690
Disease	Proteinuria	LRP2 UNC13C	2.65e-03	15	152	2	HP_0000093
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	ADAMTSL3 TRIP12 TNRC6A LRP1 NFAT5 MAML3 PLCE1	2.89e-03	364	152	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	facial morphology measurement	KIF6 EYA4 TRARG1 BCR ZNF106 TMEM132D GLI3 AGAP1	2.96e-03	466	152	8	EFO_0007841
Disease	neutrophil collagenase measurement	ABCA13 HNRNPC	3.02e-03	16	152	2	EFO_0008248
Disease	idiopathic scoliosis (implicated_via_orthology)	KIF6 PTPN11	3.02e-03	16	152	2	DOID:0060250 (implicated_via_orthology)
Disease	pre-malignant neoplasm (biomarker_via_orthology)	GLI3 ATM	3.41e-03	17	152	2	DOID:0060071 (biomarker_via_orthology)
Disease	Van Buchem disease	FLT1 LRP5	3.41e-03	17	152	2	C0432272
Disease	cervical artery dissection	LRP1 PLCE1	3.41e-03	17	152	2	EFO_1000059
Disease	lean body mass	FOXK2 LAMA2 ADGRV1 ADAMTSL3 HNRNPC GLI3 PLCE1	3.60e-03	379	152	7	EFO_0004995
Disease	neuroimaging measurement	KIF6 RALGPS2 LAMA2 RFC5 BCR ELAC2 PLIN2 ZNF106 GLI3 TNRC6A PBX3 AGAP1 PLCE1	3.65e-03	1069	152	13	EFO_0004346
Disease	leukemia (implicated_via_orthology)	PTPN11 ATM	4.26e-03	19	152	2	DOID:1240 (implicated_via_orthology)
Disease	waist-hip ratio	EYA4 FOXK2 COL15A1 ARID4A SCEL ADAMTSL3 TRIP12 DCP1B GLI3 TNRC6A PCNX1 NFAT5 MAML3 PLCE1	4.50e-03	1226	152	14	EFO_0004343
Disease	tea consumption measurement	MYT1 LAMA2 ARNT NFAT5	4.53e-03	129	152	4	EFO_0010091
Disease	hair colour measurement	NRG1 DOCK10 ADGRV1 SCEL KRT71 LRP1 LRP5 PCNX1 UNC13C	4.72e-03	615	152	9	EFO_0007822
Disease	keratoconus	COL12A1 ZNF106 AIFM3	4.84e-03	66	152	3	MONDO_0015486
Disease	alcohol consumption measurement	COL12A1 SYN3 ARID4A MFSD6 PPP1R13B ADGRV1 GALNT7 FMNL2 WDR19 GLI3 TNRC6A NFAT5 ARMH4 SORL1	5.04e-03	1242	152	14	EFO_0007878
Disease	bitter alcoholic beverage consumption measurement	PPP1R13B TNRC6A ARMH4 SORL1	5.04e-03	133	152	4	EFO_0010092

Protein segments in the cluster

Peptide	Gene	Start	Entry
EQGQQITMMRGSQES	NT5C1B	91	Q96P26
QEEMTGMNDLGERQS	ACKR2	356	O00590
EMLSMLGDQSNSYNN	ARNT	761	P27540
VSQAEMSSRQAMLEN	ABCF1	286	Q8NE71
SEAMALQSIQNMRGN	AGAP11	326	Q8TF27
QSEAMALQSIRNMRG	AGAP1	606	Q9UPQ3
QSEAMALQSIQNMRG	AGAP9	506	Q5VTM2
IENGMEMTNTVSQER	ARID4A	871	P29374
DAMSSQQNVMGTTEI	ALS2	316	Q96Q42
VSDRISSLGSQAMQM	BCR	196	P11274
AAQNMLAQEAEMSTV	AIFM3	496	Q96NN9
LELQMTRQMASSGAS	AIFM1	46	O95831
MNSDTSVQRSLVEQM	ALKBH8	531	Q96BT7
FNSMQDRVMLLADSS	ARMH4	756	Q86TY3
NNSEPSRMNMTSLDA	MASTL	666	Q96GX5
TGLMMSVNFSTQELR	ADGRV1	5526	Q8WXG9
FMMLQNANVTGSSLE	ABCA13	2026	Q86UQ4
FDTMGMTNILNNQDT	ECT2L	496	Q008S8
ASRQSFRMAMGNPSE	DVL3	696	Q92997
SDQNSTELMNSVMVR	DMTF1	636	Q9Y222
MAMSNGNNDFVVLSN	DISP1	1	Q96F81
MNGNLSAEIERFSAM	PPP1R13B	206	Q96KQ4
QKPMTDNARQMSRDT	C1orf87	51	Q8N0U7
MENFVATLANGMSLQ	PRMT1	11	Q99873
MSDRRENDMSPSNNV	RAB11A	181	P62491
LEDARQHSSSNMVIM	RAB2B	101	Q8WUD1
VQLDSDMIMSSATGN	SLC34A3	251	Q8N130
SLRSERNNMMNIANG	NRG1	281	Q02297
TAMDALNSMQNFLRG	PPME1	186	Q9Y570
LAAQSSMPENMTLQR	HECW2	31	Q9P2P5
SMPENMTLQRANSDT	HECW2	36	Q9P2P5
MDDQSRMLQTLAGVN	PBX3	1	P40426
NQGSMDALNMDTVCR	DCAF1	1371	Q9Y4B6
LEFMMRQSNSTAATN	HLA-DQA2	96	P01906
SFADRALINSMDQNM	PRKCQ	676	Q04759
SDLSGVDVTMLNMLN	GLI3	831	P10071
SDSSAAPNMQGVRMD	HCFC2	401	Q9Y5Z7
MASNVTNKTDPRSMN	HNRNPC	1	P07910
ITVLGSNSMVSMQDD	MAP1S	1036	Q66K74
RTQEELMNSNQMSSD	GOLGA1	211	Q92805
QSMRTSRLMAQNAGM	MAML3	821	Q96JK9
AGTQAESAQSNRLMM	GRWD1	91	Q9BQ67
RVMPSDLNLMADNSQ	FOXK2	226	Q01167
GDNISMANMDGSNRT	LRP1	1721	Q07954
NREVVLSSNNMDMFS	LRP1	2086	Q07954
VLQDNFLNMSRSMTS	IFI44L	366	Q53G44
SMQGSSRNISQDMTQ	ATXN3	256	P54252
RMMLQECRGTQQTDA	FAM184B	331	Q9ULE4
TDLDTNMIESSNMLG	LRP5	821	O75197
LGSENMDRGNNNVMS	DDX42	666	Q86XP3
MGIQNLQRSESSKMD	FAM135A	426	Q9P2D6
QSRLSMVNQMEPSGQ	PCNX1	2166	Q96RV3
MGSTVENSNQNRELM	PNRC1	301	Q12796
EQQEMLQAFSTQSGM	NXF1	566	Q9UBU9
MNENNETLTRGFTLM	OR2T6	1	Q8NHC8
MRDAQLNDGAMETGT	PDYN	146	P01213
NQSDFSMNLMDLNLS	HHLA2	296	Q9UM44
DTNRMIAETPMNQAS	KIF6	206	Q6ZMV9
LQLSMARIGSTVNMN	MFSD1	176	Q9H3U5
GNFMRQSRISEISME	LAMA2	1346	P24043
LNQMINSMAEDGSNR	LRP2	2486	P98164
MVRSQRSGMVQTEAQ	PTPN11	496	Q06124
SMSVAASEQQEDMAR	CDC42BPB	986	Q9Y5S2
GEITNRMMDLTLNSS	MFSD6	231	Q6ZSS7
EMMSLQSGNFLQQSS	NFAT5	1051	O94916
RLNSVSSTQGDMMQK	OLIG3	36	Q7RTU3
AMNTTVMQGFNRSER	P2RY13	21	Q9BPV8
SPTFINMSQENVDMR	ITGAD	386	Q13349
VSQMDQEQGSSFQMS	FAM189A2	201	Q15884
GFTIMNRLSMENRTE	DCP1B	71	Q8IZD4
DTNGNLMEVEDQSSM	ATM	841	Q13315
VSQSQNSRSMEMQDL	EYA4	21	O95677
GSENNMLFLSMNLTI	FCAMR	156	Q8WWV6
LTLNMTDQSGNEANM	IGSF10	316	Q6WRI0
TAEMRGNLMDTSAEQ	BBS2	321	Q9BXC9
LQMLDNTMTSNSNEI	DOCK10	1456	Q96BY6
GDIASQNMMRAVARQ	COL12A1	2896	Q99715
SQFQGLMESMRQADL	FOXJ3	481	Q9UPW0
NMVASDMISLDRSVN	GALNT7	176	Q86SF2
EQQNNCSTSLMRMES	FAM111A	31	Q96PZ2
GMELNSSITSQDVLM	DLGAP5	751	Q15398
MGNAGSMDSQQTDFR	FMNL2	1	Q96PY5
MMEGNGTENSCSRTR	MARF1	1	Q9Y4F3
QSQSFSGMTVLQRLM	GP5	66	P40197
ILGQDNAADQSRMMQ	EMC3	186	Q9P0I2
NAADQSRMMQEQMTG	EMC3	191	Q9P0I2
SRNLVTAFSNMDDML	COL15A1	1131	P39059
MAAERGAGQQQSQEM	PPP1R7	1	Q15435
MSNTQAERSIIGMID	S100A7A	1	Q86SG5
EVMQALNMSAALTAR	RYR2	1946	Q92736
AMANSEGSEAMLNRV	CNOT6	306	Q9ULM6
FLMDDNMSNTLNSLD	MYBL1	301	P10243
SGTAIMQDGNTMRNN	NEURL4	806	Q96JN8
MRNRMETVEDTNGSE	NPHP1	276	O15259
NMSNNRISAMGALSL	LRRC74B	281	Q6ZQY2
MMGQNQTSISDFLLL	OR1E2	1	P47887
MDLMNGQASSVNIAA	RALGPS2	1	Q86X27
TQLQSMPSRELASMN	RHOBTB3	516	O94955
MMGQNQTSISDFLLL	OR1E1	1	P30953
DMSDRGISNMLDVNG	RSU1	21	Q15404
MSEASGNLNSLRMAN	RTL5	1	Q5HYW3
ANTGSAMLEQVAMTE	SYN3	316	O14994
NLELGDMSLSDNASM	UTP20	1481	O75691
MDNMTSSAQIIQRSF	RBM7	121	Q9Y580
ATLINGSMNEENMRS	SORL1	426	Q92673
AMMFRQRSLSQGSTN	RAPGEF6	1061	Q8TEU7
RSNGEMDGNDLMQAS	TMEM132D	896	Q14C87
RRMEENSSGNTMSAS	PLCE1	1986	Q9P212
GDMRRALNILQSTNM	RFC5	211	P40937
MDMRLSQVSDSVSGQ	PRPF6	251	O94906
MSMGTNTNSLLDDDQ	NEXMIF	1296	Q5QGS0
QSRMRQIGTNQSGMS	SATL1	121	Q86VE3
TSLMSEMRNAQSIGR	SGO2	246	Q562F6
MADAMDTLEGRRNNN	SPATA16	506	Q9BXB7
TNKTSQLDNGMRDQM	WDR19	86	Q8NEZ3
NMTTGNMFDISDVNN	SCN3A	1366	Q9NY46
DSLNQMSGNMLNLSD	ABCB7	166	O75027
NLNVQMNSMDIRCSD	ADGRE3	211	Q9BY15
MENMQVSRGRSSVFS	ADGRG5	31	Q8IZF4
QSEAMALQSIQNMRG	AGAP5	461	A6NIR3
MQNQRSTGSFVGELM	SLC25A13	356	Q9UJS0
GMMFLQISNDINSDS	CLEC12B	61	Q2HXU8
NIGSMISNMNAARAE	CNGA1	391	P29973
VGSMISNMNATRAEF	CNGA2	371	Q16280
SMISNMNASRAEFQA	CNGA3	401	Q16281
AMANSDGSEAMLNRV	CNOT6L	306	Q96LI5
MNRNQAFGMNNSLSS	CNOT2	196	Q9NZN8
MEQMLGAFQSDLSSI	VPS52	126	Q8N1B4
VEDMEGASQANQRRM	WDTC1	621	Q8N5D0
GRNTSRMAEDTSPNM	SUN5	31	Q8TC36
GNMAQLSMASRATQV	ZBTB5	281	O15062
MFASLMNSESRLNES	USP45	471	Q70EL2
SQAISVGMRMNAEFI	ELAC2	706	Q9BQ52
MSFELNQMRANGNTT	UNC13C	1861	Q8NB66
AMVLSNLNNNMDVES	SEC16A	1706	O15027
NLNNNMDVESRTMAT	SEC16A	1711	O15027
SFMTSQLDANNMEEL	PLEKHD1	456	A6NEE1
DLNTATRMTAQNAMT	STOML1	161	Q9UBI4
SMNSARSTNILDNMG	WDHD1	926	O75717
NTLDNQLTNRSMSMF	SCEL	111	O95171
QNRMGQDSYVLMASS	ARHGAP25	121	P42331
RSMMQSLSQNPDLAA	UBQLN1	401	Q9UMX0
MSNTQAERSIIGMID	S100A7	1	P31151
SMAAVALRDSAQGMT	ZNF551	16	Q7Z340
MRQDQITNGMVNAIS	POLR3B	406	Q9NW08
TENMMTFKGNARISN	PKHD1L1	3286	Q86WI1
LDGMNFMAQSVSELS	ZFYVE1	561	Q9HBF4
MMLENDRSMASLGRN	ZNF852	36	Q6ZMS4
NTSRGQNMDDVMVLV	VSIG10	446	Q8N0Z9
SRMMQLVSSGVENAL	PLIN2	166	Q99541
ISIMSRSSMQQGNVD	TRARG1	126	Q8IXB3
NTICMSGEMLANFRN	ZMYM1	776	Q5SVZ6
SNMGNRIESITQRMA	FLT1	496	P17948
QAESVMQDLGSSRAM	TRIP12	1601	Q14669
LMSSAVQDMNCIRQA	TMEM125	86	Q96AQ2
MSPSGNRMQESQETA	XIRP1	756	Q702N8
PGRNRNSNCQMEDMT	ZNF106	246	Q9H2Y7
GIVADESQNMQFMSS	TNRC6A	1281	Q8NDV7
NSQTLGNDMLMNTPR	TIPIN	221	Q9BVW5
ENSISFQMLSLEMSG	HSD52	21	Q0P140
SLAEQFQRMQGVSMR	USP54	1131	Q70EL1
RNMSQLMETGEVSDD	ADAMTSL3	1101	P82987
SDMSVILSMDNNRNL	KRT71	281	Q3SY84
ESNSEMEAAMVQLQS	MYT1	1016	Q01538