Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	zf-RNPHF	HNRNPF HNRNPH1 HNRNPH2	2.04e-08	3	52	3	PF08080
Domain	Znf_CHHC	HNRNPF HNRNPH1 HNRNPH2	2.04e-08	3	52	3	IPR012996
Domain	RRM_1	RBM44 HNRNPF HNRNPH1 HNRNPH2	2.66e-03	208	52	4	PF00076
Domain	RRM	RBM44 HNRNPF HNRNPH1 HNRNPH2	3.10e-03	217	52	4	SM00360
Domain	RRM_dom	RBM44 HNRNPF HNRNPH1 HNRNPH2	3.64e-03	227	52	4	IPR000504
Domain	RRM	RBM44 HNRNPF HNRNPH1 HNRNPH2	3.82e-03	230	52	4	PS50102
Domain	-	RBM44 HNRNPF HNRNPH1 HNRNPH2	4.71e-03	244	52	4	3.30.70.330
Domain	BROMODOMAIN_1	BRD7 ASH1L	4.76e-03	37	52	2	PS00633
Domain	Bromodomain	BRD7 ASH1L	5.01e-03	38	52	2	PF00439
Domain	Nucleotide-bd_a/b_plait	RBM44 HNRNPF HNRNPH1 HNRNPH2	5.73e-03	258	52	4	IPR012677
Domain	BROMODOMAIN_2	BRD7 ASH1L	5.82e-03	41	52	2	PS50014
Domain	BROMO	BRD7 ASH1L	6.10e-03	42	52	2	SM00297
Domain	Bromodomain	BRD7 ASH1L	6.10e-03	42	52	2	IPR001487
Domain	-	BRD7 ASH1L	6.10e-03	42	52	2	1.20.920.10
Domain	PH	OSBPL3 ARHGEF12 PLD1 SYNGAP1	7.43e-03	278	52	4	SM00233
Domain	PH_DOMAIN	OSBPL3 ARHGEF12 PLD1 SYNGAP1	7.52e-03	279	52	4	PS50003
Domain	PH_domain	OSBPL3 ARHGEF12 PLD1 SYNGAP1	7.61e-03	280	52	4	IPR001849
Pubmed	hnRNPs H, H' and F behave differently with respect to posttranslational cleavage and subcellular localization.	HNRNPF HNRNPH1 HNRNPH2	3.74e-09	3	55	3	10456323
Pubmed	Heterogeneous nuclear ribonucleoproteins F and H/H' show differential expression in normal and selected cancer tissues.	HNRNPF HNRNPH1 HNRNPH2	3.74e-09	3	55	3	14980514
Pubmed	Heterogeneous nuclear ribonucleoproteins H, H', and F are members of a ubiquitously expressed subfamily of related but distinct proteins encoded by genes mapping to different chromosomes.	HNRNPF HNRNPH1 HNRNPH2	3.74e-09	3	55	3	7499401
Pubmed	A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.	HSPA1L HNRNPF HNRNPH1 HNRNPH2	3.97e-07	38	55	4	18247557
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	VPS39 BRD7 NOC3L PLOD2 DICER1 HNRNPF HNRNPH1 HNRNPH2	4.46e-07	440	55	8	34244565
Pubmed	Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex.	HNRNPF HNRNPH1 HNRNPH2	6.12e-07	11	55	3	21900255
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	VPS39 PLD1 PLOD2 DICER1 MRPS22 HNRNPF HNRNPH1 HNRNPH2	6.43e-07	462	55	8	31138677
Pubmed	A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1.	HNRNPF HNRNPH1 HNRNPH2	8.15e-07	12	55	3	37463454
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	NUSAP1 SERPINA1 HJURP BRD7 SYCP1 PLOD2 MRPS22 HNRNPF HNRNPH1 STN1 CA2	1.62e-06	1155	55	11	20360068
Pubmed	Tandem immunoprecipitation approach to identify HIV-1 Gag associated host factors.	HNRNPF HNRNPH1 HNRNPH2	2.07e-06	16	55	3	24690621
Pubmed	SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation.	PLOD2 HSPA1L MRPS22 HNRNPF HNRNPH1 HNRNPH2	2.16e-06	239	55	6	23246001
Pubmed	Reduction of protein kinase C α (PKC-α) promote apoptosis via down-regulation of Dicer in bladder cancer.	PRKCA DICER1	2.46e-06	2	55	2	25752336
Pubmed	The hnRNP F protein: unique primary structure, nucleic acid-binding properties, and subcellular localization.	HNRNPF HNRNPH1	2.46e-06	2	55	2	7512260
Pubmed	The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells.	HNRNPF HNRNPH2	2.46e-06	2	55	2	37399401
Pubmed	Protein kinase C alpha associates with phospholipase D1 and enhances basal phospholipase D activity in a protein phosphorylation-independent manner in human melanoma cells.	PRKCA PLD1	2.46e-06	2	55	2	12839565
Pubmed	Nuclear localization of phospholipase D1 mediates the activation of nuclear protein kinase C(alpha) and extracellular signal-regulated kinase signaling pathways.	PRKCA PLD1	2.46e-06	2	55	2	21113078
Pubmed	The small RNA mascRNA differentially regulates TLR-induced proinflammatory and antiviral responses.	HNRNPF HNRNPH1	2.46e-06	2	55	2	34582376
Pubmed	Post-transcriptional regulation of mu-opioid receptor: role of the RNA-binding proteins heterogeneous nuclear ribonucleoprotein H1 and F.	HNRNPF HNRNPH1	2.46e-06	2	55	2	21739230
Pubmed	Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCα.	PRKCA PLD1	2.46e-06	2	55	2	28125719
Pubmed	Global profiling of alternative splicing events and gene expression regulated by hnRNPH/F.	HNRNPF HNRNPH1	2.46e-06	2	55	2	23284676
Pubmed	Phosphorylation and activation of phospholipase D1 by protein kinase C in vivo: determination of multiple phosphorylation sites.	PRKCA PLD1	2.46e-06	2	55	2	10441128
Pubmed	Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex.	HNRNPF HNRNPH1 HNRNPH2	5.64e-06	22	55	3	18377426
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	NUSAP1 SEPTIN8 VPS39 OSBPL3 HJURP ASH1L ZBTB41 PLD1 STK24 HNRNPF	6.79e-06	1084	55	10	11544199
Pubmed	A glycine-rich domain of hnRNP H/F promotes nucleocytoplasmic shuttling and nuclear import through an interaction with transportin 1.	HNRNPF HNRNPH1	7.36e-06	3	55	2	20308327
Pubmed	Click chemistry-enabled CRISPR screening reveals GSK3 as a regulator of PLD signaling.	PRKCA PLD1	7.36e-06	3	55	2	34810254
Pubmed	Rapid mitogenic regulation of the mTORC1 inhibitor, DEPTOR, by phosphatidic acid.	DEPTOR PLD1	7.36e-06	3	55	2	25936805
Pubmed	Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs.	HNRNPF HNRNPH1	7.36e-06	3	55	2	19244236
Pubmed	hnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cells.	HNRNPF HNRNPH1	7.36e-06	3	55	2	9858532
Pubmed	Heterogeneous nuclear ribonucleoprotein H1/H2-dependent unsplicing of thymidine phosphorylase results in anticancer drug resistance.	HNRNPH1 HNRNPH2	7.36e-06	3	55	2	21068389
Pubmed	Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.	CCDC88A MRPS22 HNRNPF HNRNPH1 HNRNPH2	7.95e-06	172	55	5	23184937
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	ARHGEF12 ANKRD36 HSPA1L HNRNPF HNRNPH1	1.19e-05	187	55	5	26460568
Pubmed	Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.	HSPA1L HNRNPF HNRNPH1	1.19e-05	28	55	3	38492217
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CCDC182 SPEF2 NUCB2 NOC3L ASH1L VPS13A SYCP1 ZBTB41 NEB HSPA1L HNRNPF	1.34e-05	1442	55	11	35575683
Pubmed	Interaction between the human nuclear cap-binding protein complex and hnRNP F.	HNRNPF HNRNPH1	1.47e-05	4	55	2	9111328
Pubmed	A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction.	HNRNPF HNRNPH1	1.47e-05	4	55	2	25169827
Pubmed	Regulation of Mcl-1 alternative splicing by hnRNP F, H1 and K in breast cancer cells.	HNRNPF HNRNPH1	1.47e-05	4	55	2	30468106
Pubmed	An intronic G run within HIV-1 intron 2 is critical for splicing regulation of vif mRNA.	HNRNPF HNRNPH1	1.47e-05	4	55	2	23255806
Pubmed	Restricted epithelial proliferation by lacritin via PKCalpha-dependent NFAT and mTOR pathways.	PRKCA PLD1	1.47e-05	4	55	2	16923831
Pubmed	Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.	CCDC88A GOLIM4 HNRNPF HNRNPH1 CA2	1.69e-05	201	55	5	25192599
Pubmed	Profiling of Parkin-binding partners using tandem affinity purification.	MRPS15 HSPA1L MRPS22 HNRNPF HNRNPH1	1.77e-05	203	55	5	24244333
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TXLNA CCDC88A NUCB2 NOC3L VPS13A ANKRD11 CHD1 PLOD2 HSPA1L DICER1 MRPS22	1.78e-05	1487	55	11	33957083
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	NUSAP1 SEPTIN8 SERPINA1 HJURP MRPS22 HNRNPF ALOX12B HNRNPH2	1.89e-05	732	55	8	34732716
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	NUSAP1 TXLNA NOC3L MRPS15 ARHGEF12 HSPA1L MRPS22 HNRNPF HNRNPH2	1.99e-05	971	55	9	33306668
Pubmed	The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.	MRPS15 DICER1 MRPS22 HNRNPF HNRNPH1	2.60e-05	220	55	5	34091597
Pubmed	Evidence that dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1.	HNRNPF HNRNPH2	3.67e-05	6	55	2	11054566
Pubmed	Participation of phospholipase D and alpha/beta-protein kinase C in growth factor-induced signalling in C3H10T1/2 fibroblasts.	PRKCA PLD1	3.67e-05	6	55	2	12782152
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	NOC3L MRPS15 PRKCA CHD1 HSPA1L HNRNPF ALOX12B HNRNPH1 HNRNPH2 ZBED5	4.55e-05	1353	55	10	29467282
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	NUSAP1 RCBTB1 CHD1 HNRNPF HNRNPH1 HNRNPH2	4.67e-05	411	55	6	35182466
Pubmed	Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein.	HNRNPF HNRNPH1	5.13e-05	7	55	2	11003644
Pubmed	A Mutation in Hnrnph1 That Decreases Methamphetamine-Induced Reinforcement, Reward, and Dopamine Release and Increases Synaptosomal hnRNP H and Mitochondrial Proteins.	HNRNPH1 HNRNPH2	5.13e-05	7	55	2	31704785
Pubmed	Age-related expression analysis of mouse liver nuclear protein binding to 3'-untranslated region of Period2 gene.	HNRNPH1 HNRNPH2	5.13e-05	7	55	2	25846207
Pubmed	Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.	VPS13A MRPS22 HNRNPF HNRNPH1 HNRNPH2	5.35e-05	256	55	5	24189400
Pubmed	Let-7b and miR-495 stimulate differentiation and prevent metaplasia of pancreatic acinar cells by repressing HNF6.	PRKCA DICER1 CA2	5.41e-05	46	55	3	23684747
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	OSBPL3 MRPS15 HNRNPF HNRNPH1 HNRNPH2	5.55e-05	258	55	5	37794589
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	SEPTIN8 TXLNA CCDC88A OSBPL3 NOC3L PRKCA HNRNPH1 HNRNPH2	5.57e-05	853	55	8	28718761
Pubmed	TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.	VPS13A CHD1 HSPA1L HNRNPF HNRNPH1 HNRNPH2	5.99e-05	430	55	6	38172120
Pubmed	Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.	HNRNPF HNRNPH1 HNRNPH2	6.55e-05	49	55	3	27352031
Pubmed	RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.	HSPA1L HNRNPF HNRNPH1 HNRNPH2	9.07e-05	148	55	4	35676246
Pubmed	Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.	DICER1 HNRNPF HNRNPH2	1.03e-04	57	55	3	17932509
Pubmed	Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.	HSPA1L HNRNPH1	1.10e-04	10	55	2	19299493
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	BRD7 NOC3L HSPA1L HNRNPF HNRNPH1 STN1	1.17e-04	486	55	6	30940648
Pubmed	[Genetic predisposition to development of toxic liver cirrhosis caused by alcohol].	CYP1A1 SERPINA1	1.34e-04	11	55	2	11436564
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SERPINA1 CCDC88A VPS39 OSBPL3 NUCB2 PLD1 MRPS22	1.34e-04	719	55	7	35337019
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	ARHGEF12 HSPA1L HNRNPF HNRNPH1 HNRNPH2	1.46e-04	317	55	5	17620599
Pubmed	Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA.	HSPA1L HNRNPF HNRNPH1	1.52e-04	65	55	3	34645483
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	CCDC88A NEB HSPA1L STK24 HNRNPF HNRNPH1	1.57e-04	513	55	6	25798074
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	NUCB2 VPS13A PRKCA DICER1 MRPS22 HNRNPH1	1.61e-04	515	55	6	31617661
Pubmed	Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.	HSPA1L HNRNPF HNRNPH1	1.67e-04	67	55	3	29863498
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	DICER1 HNRNPF HNRNPH1 HNRNPH2	1.73e-04	175	55	4	25756610
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NUSAP1 TXLNA HJURP NOC3L MRPS22 HNRNPF HNRNPH1	1.87e-04	759	55	7	35915203
Pubmed	RhoG signals in parallel with Rac1 and Cdc42.	ARHGEF12 PLD1	1.89e-04	13	55	2	12376551
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	DEPTOR RCBTB1 OSBPL3 ANKRD11 STK24 DICER1	1.99e-04	536	55	6	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	DEPTOR RCBTB1 OSBPL3 ANKRD11 STK24 DICER1	2.03e-04	538	55	6	10512203
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	HSPA1L MRPS22 HNRNPF HNRNPH1 HNRNPH2	2.13e-04	344	55	5	36282215
Pubmed	hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.	MRPS15 MRPS22 HNRNPF HNRNPH1 HNRNPH2	2.19e-04	346	55	5	25324306
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	NEK1 MRPS15 DICER1 MRPS22 HNRNPF HNRNPH2	2.22e-04	547	55	6	37267103
Pubmed	The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression.	HSPA1L HNRNPF HNRNPH1	2.24e-04	74	55	3	35102251
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	NUSAP1 MRPS15 PLOD2 HSPA1L DICER1 MRPS22 HNRNPF HNRNPH1 HNRNPH2	2.28e-04	1335	55	9	29229926
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	DEPTOR STN1	2.54e-04	15	55	2	23583980
Pubmed	FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator).	HNRNPF HNRNPH1	2.54e-04	15	55	2	27365398
Pubmed	Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress.	MRPS22 HNRNPF HNRNPH1	2.62e-04	78	55	3	16236267
Pubmed	Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.	STK24 HNRNPH1 HNRNPH2	2.72e-04	79	55	3	14729942
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	TXLNA NOC3L GOLIM4 MRPS22 HNRNPF HNRNPH1 HNRNPH2	2.76e-04	809	55	7	32129710
Pubmed	Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation.	PRKCA CA2	2.90e-04	16	55	2	8630490
Pubmed	A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons.	HNRNPF HNRNPH1	3.29e-04	17	55	2	12388589
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	NEK1 CCDC88A ARHGEF12 DICER1	3.40e-04	209	55	4	36779422
Pubmed	Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.	TXLNA HSPA1L HNRNPH1	3.61e-04	87	55	3	24169447
Pubmed	Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.	NUSAP1 PLOD2 HSPA1L HNRNPH1 HNRNPH2	3.79e-04	390	55	5	17643375
Pubmed	DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.	HNRNPF HNRNPH1 HNRNPH2	3.86e-04	89	55	3	22446626
Pubmed	Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.	NUSAP1 HNRNPH1 HNRNPH2	3.99e-04	90	55	3	33087562
Pubmed	Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin.	SERPINA1 HNRNPH1 CA2	3.99e-04	90	55	3	1602151
Pubmed	hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells.	HNRNPF HNRNPH1	4.13e-04	19	55	2	35739118
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	TXLNA HNRNPF HNRNPH1 HNRNPH2 CA2	4.21e-04	399	55	5	35987950
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	NUSAP1 MRPS15 CHD1 HSPA1L MRPS22 HNRNPF HNRNPH1 HNRNPH2	4.35e-04	1153	55	8	29845934
Pubmed	Association of linear growth impairment in pediatric Crohn's disease and a known height locus: a pilot study.	HHIP ZNF678	4.58e-04	20	55	2	20846217
Pubmed	A New Cellular Interactome of SARS-CoV-2 Nucleocapsid Protein and Its Biological Implications.	HSPA1L HNRNPF HNRNPH1	4.67e-04	95	55	3	37211047
Pubmed	Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.	TXLNA MRPS15 CHD1 MRPS22	4.72e-04	228	55	4	30471916
Pubmed	Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.	SEPTIN8 TXLNA HNRNPF HNRNPH1 HNRNPH2	4.82e-04	411	55	5	36652389
Pubmed	Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.	SERPINA1 CCDC197	5.06e-04	21	55	2	15014966
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	CCDC88A HSPA1L DICER1 MRPS22 HNRNPF HNRNPH1	5.07e-04	639	55	6	23443559
Interaction	UBL4A interactions	DEPTOR PRKCA PLOD2 HSPA1L MRPS22 HNRNPF HNRNPH1 HNRNPH2	3.88e-06	349	54	8	int:UBL4A
Interaction	SIRT6 interactions	TXLNA VPS39 BRD7 NOC3L PLOD2 HSPA1L DICER1 HNRNPF HNRNPH1 HNRNPH2	5.58e-06	628	54	10	int:SIRT6
Interaction	NPM1 interactions	RBM44 HJURP BRD7 NOC3L SYCP1 PRKCA CHD1 NEB DICER1 MRPS22 HNRNPH1 HNRNPH2 SYNGAP1	1.25e-05	1201	54	13	int:NPM1
Interaction	ARHGEF39 interactions	BRD7 HNRNPF HNRNPH1 HNRNPH2	1.52e-05	56	54	4	int:ARHGEF39
Interaction	PTBP2 interactions	DEPTOR BRD7 HNRNPF HNRNPH1	4.14e-05	72	54	4	int:PTBP2
Interaction	MBNL1 interactions	SEPTIN8 SERPINA1 HNRNPF ALOX12B HNRNPH1 HNRNPH2	5.27e-05	249	54	6	int:MBNL1
Interaction	HDAC11 interactions	HHIP OSBPL3 HJURP DICER1 HNRNPH1	5.71e-05	154	54	5	int:HDAC11
Cytoband	15q15.1	NUSAP1 VPS39	1.47e-03	47	55	2	15q15.1
GeneFamily	RNA binding motif containing	RBM44 HNRNPF HNRNPH1 HNRNPH2	7.36e-04	213	35	4	725
Coexpression	GABRIELY_MIR21_TARGETS	NEK1 OSBPL3 VPS13A ARHGEF12 PLD1 REV3L	2.83e-05	289	54	6	M2196
Coexpression	SEIDEN_ONCOGENESIS_BY_MET	ARHGEF12 PLOD2 HNRNPH2 ZBED5	3.45e-05	89	54	4	M3231
Coexpression	LAKE_ADULT_KIDNEY_C6_PROXIMAL_TUBULE_EPITHELIAL_CELLS_FIBRINOGEN_POS_S3	SERPINA1 ASH1L VPS13A CHD1 DICER1	3.57e-05	181	54	5	M39225
Coexpression	ZHENG_CORD_BLOOD_C7_PUTATIVE_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_1	NUCB2 CHD1 ANKRD36 HNRNPH1	4.64e-05	96	54	4	M39216
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	NUSAP1 NEK1 CCDC88A NUCB2 NOC3L GOLIM4 CHD1 REV3L	5.56e-05	656	54	8	M18979
Coexpression	GSE40273_XBP1_KO_VS_WT_TREG_DN	OSBPL3 VPS13A ARHGEF12 CCDC122 REV3L	5.61e-05	199	54	5	M9124
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1	SEPTIN8 HHIP CCDC88A ASH1L VPS13A ARHGEF12 GOLIM4 ZBTB41 REV3L STN1 SYNGAP1	3.46e-06	780	54	11	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	NUSAP1 SEPTIN8 NEK1 CCDC88A ASH1L VPS13A GOLIM4 CHD1 ZBTB41 SYNGAP1	4.00e-05	831	54	10	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	NUSAP1 SERPINA1 CCDC88A RCBTB1 BRD7 VPS13A CHD1 REV3L DICER1 MRPS22 HNRNPH1 CA2	5.93e-05	1257	54	12	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	CCDC88A HJURP ASH1L VPS13A ANKRD11 ANKRD36	1.36e-07	192	55	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	CCDC88A BRD7 ANKRD11 ARHGEF12 GOLIM4 REV3L	1.68e-07	199	55	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	OSBPL3 ASH1L VPS13A ANKRD36 HNRNPH1	2.95e-06	181	55	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ASH1L ANKRD11 CHD1 ANKRD36 HNRNPH1	3.55e-06	188	55	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ASH1L PRKCA CHD1 ANKRD36 HNRNPH1	3.93e-06	192	55	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L VPS13A ANKRD11 PRKCA REV3L	4.24e-06	195	55	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ASH1L ANKRD11 PRKCA ANKRD36 HNRNPH1	4.24e-06	195	55	5	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L VPS13A ANKRD11 PRKCA REV3L	4.24e-06	195	55	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L ARHGEF12 HNRNPF HNRNPH1 HNRNPH2	4.35e-06	196	55	5	151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell	facs-Tongue-nan-3m-Epithelial\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF12 GOLIM4 HNRNPF HNRNPH1 HNRNPH2	4.57e-06	198	55	5	2f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCell	facs-Tongue-nan-3m\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF12 GOLIM4 HNRNPF HNRNPH1 HNRNPH2	4.57e-06	198	55	5	f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ASH1L VPS13A ANKRD11 ANKRD36 HNRNPH1	4.68e-06	199	55	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF12 GOLIM4 HNRNPF HNRNPH1 HNRNPH2	4.68e-06	199	55	5	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 NEB HSPA1L ALOX12B	4.67e-05	161	55	4	2165897924c790fec43502283f1df221c56c1e9f
ToppCell	severe-Myeloid-mDC\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CCDC88A DEPTOR NOC3L CA2	5.51e-05	168	55	4	eff37a92d41624924201372cc09f9eb07b60aec1
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells\|World / Lineage, cell class and subclass	NUSAP1 HJURP ARHGEF12 CA2	8.88e-05	190	55	4	6c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCell	3'_v3-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	NUSAP1 CCDC88A HJURP ZNF730	9.06e-05	191	55	4	aa9c0b1b90cdb7a95d4e6332819f82cae0a79ff9
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast\|World / Lineage, cell class and subclass	DEPTOR SYCP1 GOLIM4 PLOD2	9.62e-05	194	55	4	f054d78429364622d402ce1d9bf6ad13a1a1bf7e
ToppCell	normal_Lung-Epithelial_cells-AT2\|Epithelial_cells / Location, Cell class and cell subclass	HHIP SERPINA1 GOLIM4 CA2	9.82e-05	195	55	4	81e13fe337f1d0a83d0deb86a0df797d306cd24d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SEPTIN8 HHIP DICER1 CA2	9.82e-05	195	55	4	1e28617ca55e5f318a228357737b968dfac8cca0
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF12 HNRNPF HNRNPH1 HNRNPH2	1.00e-04	196	55	4	66d76249bd2770cdddff2c1fe59a016e95da2124
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF12 HNRNPF HNRNPH1 HNRNPH2	1.00e-04	196	55	4	9bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SPEF2 VPS13A ANKRD36 HNRNPH1	1.02e-04	197	55	4	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	Epithelial_cells-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	HHIP SERPINA1 MRPS15 CA2	1.02e-04	197	55	4	59aa28a377315dfcda4d9b6ecd3419157654f24e
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HHIP SERPINA1 MRPS15 CA2	1.02e-04	197	55	4	d2a4d7e92e91bcc47a7657da2e5c8a3ad7eb08ad
ToppCell	mLN-T_cell-cycling_gd_T\|T_cell / Region, Cell class and subclass	NUSAP1 HJURP GOLIM4 ZNF730	1.06e-04	199	55	4	c81a194f8c2f120c6c4d74857912865a3c2fe1e7
ToppCell	human_hepatoblastoma-Tumor_cells-T9\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NOC3L CHD1 PLOD2 CA2	1.06e-04	199	55	4	e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	BRD7 ANKRD11 ANKRD36 REV3L	1.06e-04	199	55	4	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	(1)_T_cell-(18)_cycling_gd_T\|(1)_T_cell / shred on Cell_type and subtype	NUSAP1 HJURP GOLIM4 ZNF730	1.06e-04	199	55	4	9369d0e4efe809e3e8757294ebebba5a47b30528
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 NEK1 GOLIM4 HNRNPH1	1.08e-04	200	55	4	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUSAP1 SERPINA1 CCDC88A HJURP	1.08e-04	200	55	4	5e1b38e2aa8901bfb2623249f7b6302e97d56ace
ToppCell	mLN-T_cell-cycling_gd_T\|mLN / Region, Cell class and subclass	NUSAP1 HJURP GOLIM4 ZNF730	1.08e-04	200	55	4	4efeef51f885ee8f6dd3911a536cc49e3c14da98
ToppCell	Parenchyma_Control_(B.)\|World / Sample group, Lineage and Cell type	CCDC88A GOLIM4 HNRNPH1 CA2	1.08e-04	200	55	4	220b6e5f936b3d08b031d6cabc5793213b98b8e2
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Type_2_alveolar\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	HHIP SERPINA1 MRPS15 CA2	1.08e-04	200	55	4	e6fea85df357731aad343e412672b5828403029f
ToppCell	mLN-(1)_T_cell-(18)_cycling_gd_T\|mLN / shred on region, Cell_type, and subtype	NUSAP1 HJURP GOLIM4 ZNF730	1.08e-04	200	55	4	e8a0a88a8344e80783931115bbe6cd5b62a4c1f7
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BRD7 ASH1L ANKRD11 CHD1	1.08e-04	200	55	4	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	NUSAP1 NEK1 GOLIM4 HNRNPH1	1.08e-04	200	55	4	3d932765c31aef1f80a118d51e8e66c50a758dbb
Disease	N-acetylglucosaminylasparagine measurement	SERPINA1 PRKCA	3.04e-05	5	52	2	EFO_0800151
Disease	Carcinoma, Granular Cell	SERPINA1 SYCP1 ALOX12B CA2	5.31e-05	116	52	4	C0205644
Disease	Adenocarcinoma, Tubular	SERPINA1 SYCP1 ALOX12B CA2	5.31e-05	116	52	4	C0205645
Disease	Adenocarcinoma, Oxyphilic	SERPINA1 SYCP1 ALOX12B CA2	5.31e-05	116	52	4	C0205642
Disease	Carcinoma, Cribriform	SERPINA1 SYCP1 ALOX12B CA2	5.31e-05	116	52	4	C0205643
Disease	Adenocarcinoma, Basal Cell	SERPINA1 SYCP1 ALOX12B CA2	5.31e-05	116	52	4	C0205641
Disease	Adenocarcinoma	SERPINA1 SYCP1 ALOX12B CA2	5.31e-05	116	52	4	C0001418
Disease	chronic obstructive pulmonary disease (is_implicated_in)	CYP1A1 HHIP SERPINA1	1.90e-04	63	52	3	DOID:3083 (is_implicated_in)
Disease	Liver carcinoma	NUSAP1 CYP1A1 HHIP SERPINA1 HJURP CA2	2.60e-04	507	52	6	C2239176
Disease	Cardiac Hypertrophy	CYP1A1 PRKCA PLD1	4.14e-04	82	52	3	C1383860
Disease	Cardiomegaly	CYP1A1 PRKCA PLD1	4.14e-04	82	52	3	C0018800
Disease	Sjogren's syndrome (is_implicated_in)	CYP1A1 HNRNPH1	4.58e-04	18	52	2	DOID:12894 (is_implicated_in)
Disease	Neurodevelopmental Disorders	ASH1L ANKRD11 SYNGAP1	5.99e-04	93	52	3	C1535926
Disease	mean fractional anisotropy measurement	DEPTOR ANKRD11 STN1	6.37e-04	95	52	3	EFO_0008399
Disease	Prostatic Neoplasms	CYP1A1 NUCB2 ASH1L CHD1 ALOX12B HNRNPH1	7.28e-04	616	52	6	C0033578
Disease	Malignant neoplasm of prostate	CYP1A1 NUCB2 ASH1L CHD1 ALOX12B HNRNPH1	7.28e-04	616	52	6	C0376358
Disease	HOMA-IR	SPEF2 MRPS22	1.55e-03	33	52	2	EFO_0004501
Disease	Chronic Obstructive Airway Disease	CYP1A1 SERPINA1	1.55e-03	33	52	2	C0024117
Disease	Chronic Airflow Obstruction	CYP1A1 SERPINA1	1.55e-03	33	52	2	C1527303

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEHLESHKKYKERKE	AKAP2	256	Q9Y2D5
KDAVGERYKHKEKHR	ASH1L	1521	Q9NR48
VLKHDRDHFKKEEKL	ANKRD11	686	Q6UB99
KKHKSDKHLYEEYVE	BRD7	6	Q9NPI1
VDKFLEDVKKLYHSE	SERPINA1	151	P01009
KYLKDFEIVKRKHED	ANKRD36	1536	A6QL64
KYIKHEQEELHRKFL	DICER1	331	Q9UPY3
REVEKHKLFEDYLIK	CCDC197	41	Q8NCU1
TEFDARKLHKLYKHA	CHD1	1486	O14646
YIHKIEADLEHLKKV	ARHGEF12	1506	Q9NZN5
RYDEIKEEFDKLHQK	HJURP	576	Q8NCD3
DLKFRIDGKYIHVHK	RCBTB1	371	Q8NDN9
REYHDLKHEKYKEQE	RBM44	271	Q6ZP01
VKEHYKTFEKGHIRD	CYP1A1	266	P04798
FHKKIKEAFEVFDHE	EFCAB2	151	Q5VUJ9
KVVDEKYKDHFTEIL	MAGEB1	136	P43366
KFFEVYEKIKAIHED	NEK1	1201	Q96PY6
IEFEKRQIKKELEHY	CCDC88A	606	Q3V6T2
KHKERIGHRYIEIFK	HNRNPH2	171	P55795
SHFVEEFKRKHKKDI	HSPA1L	241	P34931
KHKERIGHRYIEIFK	HNRNPH1	171	P31943
QYIERKKKHFEEHNS	NUSAP1	201	Q9BXS6
LEHYDKTRHEEFKKY	NUCB2	166	P80303
ELEDFKKEALKSIHY	CCDC182	61	A6NF36
FIHNKEVYHEKDIKV	PLOD2	331	O00469
EHKKAKEDFLVYKLE	GOLIM4	81	O00461
HEKLRKEIEVQHKRY	CCDC122	216	Q5T0U0
VKKFHKYEEEIDIHN	FIG4	661	Q92562
EEKVIKDRRHHLKTY	DEPTOR	46	Q8TB45
EHRKEEIRAKQDFYH	ALOX12B	131	O75342
EKVHLYHSIEKEKTV	SLC15A5	11	A6NIM6
EHIYHLKVKSEEVFD	OSBPL3	121	Q9H4L5
HAKKRKHERIIDKYE	NOC3L	121	Q8WTT2
KHKERIGHRYIEVFK	HNRNPF	171	P52597
IRSYEEHLEKHRKDK	MRPS15	136	P82914
EYIKVHHKTYEDIDK	MRPS22	241	P82650
EKYKHVKEDLAHLHF	SPEF2	161	Q9C093
YYVTREDKDLHRKIH	STN1	291	Q9H668
VHEVKDHKFIARFFK	PRKCA	31	P17252
VKRKFKHFQEFHREL	PLD1	116	Q13393
YLHSEKKIHRDIKAA	STK24	146	Q9Y6E0
EYDKVEEISRKHKHN	HHIP	201	Q96QV1
EHTVDKKKYAAELHL	CA2	106	P00918
HKRIHTEEKPYKCEE	ZNF678	451	Q5SXM1
VKHTEKLEREFKEYT	VPS13A	2571	Q96RL7
KLKIRYEEFQEHKTE	REV3L	771	O60673
KEYEEEIHSLKERLH	SYNGAP1	1196	Q96PV0
IDKEKDRFEHELQKY	SOGA3	546	Q5TF21
KHKHQYDKIIEERDS	SYCP1	716	Q15431
KDKLKYHIDHVHEIK	ZBTB41	736	Q5SVQ8
EKERELHEKFEHLKR	SEPTIN8	361	Q92599
FYVEELKARFHDEKK	PRPF40B	546	Q6NWY9
HKIIHTVEKFYKCEE	ZNF730	386	Q6ZMV8
RHLETKHAAYKDKDI	ZBED5	151	Q49AG3
YELREEHIDKVFKHK	TXLNA	316	P40222
ESEHVLKKAHKYSEL	VPS39	491	Q96JC1
HAKHAYDLRDDIKYK	NEB	4866	P20929