Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.08e-05	55	106	5	GO:0042974
GeneOntologyMolecularFunction	taste receptor activity	TAS2R36 TAS1R1 TAS2R20 TAS2R30	2.73e-05	33	106	4	GO:0008527
GeneOntologyMolecularFunction	nuclear receptor binding	WBP2 PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 MMS19 PRAMEF6	6.30e-05	187	106	7	GO:0016922
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	7.56e-05	82	106	5	GO:1990756
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.52e-04	95	106	5	GO:0140767
GeneOntologyMolecularFunction	kynurenine-oxoglutarate transaminase activity	AADAT GOT2	1.66e-04	4	106	2	GO:0016212
GeneOntologyMolecularFunction	pyridoxal phosphate binding	SDSL AADAT KYNU GOT2	2.23e-04	56	106	4	GO:0030170
GeneOntologyMolecularFunction	vitamin B6 binding	SDSL AADAT KYNU GOT2	2.39e-04	57	106	4	GO:0070279
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R36 TAS2R20 TAS2R30	3.88e-04	27	106	3	GO:0033038
GeneOntologyMolecularFunction	DEAD/H-box RNA helicase binding	AKAP8L DROSHA	9.81e-04	9	106	2	GO:0017151
GeneOntologyBiologicalProcess	L-kynurenine metabolic process	AADAT KYNU GOT2	4.42e-06	7	105	3	GO:0097052
GeneOntologyBiologicalProcess	kynurenine metabolic process	AADAT KYNU GOT2	2.05e-05	11	105	3	GO:0070189
GeneOntologyBiologicalProcess	blastocyst formation	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	4.88e-05	78	105	5	GO:0001825
GeneOntologyBiologicalProcess	L-amino acid catabolic process	SDSL PPAT AADAT KYNU GOT2	5.51e-05	80	105	5	GO:0170035
GeneOntologyBiologicalProcess	aspartate family amino acid catabolic process	SDSL AADAT GOT2	5.58e-05	15	105	3	GO:0009068
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of taste	TAS2R36 TAS1R1 TAS2R20 TAS2R30	1.22e-04	50	105	4	GO:0050912
GeneOntologyBiologicalProcess	oocyte development	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.52e-04	99	105	5	GO:0048599
GeneOntologyBiologicalProcess	organelle fission	NCAPD3 TOPBP1 CIT KIF20B AKAP8L FANCD2 PRMT5 CENPI KDR NUDC TDRD12	1.58e-04	571	105	11	GO:0048285
GeneOntologyBiologicalProcess	oocyte differentiation	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.83e-04	103	105	5	GO:0009994
GeneOntologyBiologicalProcess	alpha-amino acid catabolic process	SDSL PPAT AADAT KYNU GOT2	1.92e-04	104	105	5	GO:1901606
GeneOntologyBiologicalProcess	somatic stem cell population maintenance	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.28e-04	108	105	5	GO:0035019
GeneOntologyCellularComponent	motile cilium	PRAMEF7 PRAMEF5 DNAH2 PRAMEF12 SSX8P PRAMEF8 DNAH1 VPS13A TAS2R20 TAS2R30 PRAMEF6	1.91e-06	355	106	11	GO:0031514
GeneOntologyCellularComponent	Cul2-RING ubiquitin ligase complex	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.95e-06	47	106	5	GO:0031462
GeneOntologyCellularComponent	ubiquitin ligase complex	PRAMEF7 AMFR PRAMEF5 PRAMEF12 PRAMEF8 FBH1 ANAPC1 PRAMEF6 ARMC8	7.69e-05	352	106	9	GO:0000151
GeneOntologyCellularComponent	acrosomal vesicle	PRAMEF7 PRSS2 PRAMEF5 PRAMEF12 PRAMEF8 SPACA6 PRAMEF6	8.71e-05	206	106	7	GO:0001669
GeneOntologyCellularComponent	cullin-RING ubiquitin ligase complex	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 FBH1 ANAPC1 PRAMEF6	1.04e-04	212	106	7	GO:0031461
GeneOntologyCellularComponent	cilium	CYLD PRAMEF7 PRAMEF5 DNAH2 PRAMEF12 SSX8P PRAMEF8 DNAH1 VPS13A TRPV4 TAS2R20 TAS2R30 PRAMEF6	6.16e-04	898	106	13	GO:0005929
GeneOntologyCellularComponent	inner dynein arm	DNAH2 DNAH1	1.12e-03	10	106	2	GO:0036156
GeneOntologyCellularComponent	transferase complex	PRAMEF7 AMFR PRAMEF5 PRAMEF12 PRAMEF8 YEATS2 FBH1 ANAPC1 PRMT5 KMT2A MMS19 PRAMEF6 ARMC8	1.17e-03	963	106	13	GO:1990234
GeneOntologyCellularComponent	intracellular protein-containing complex	PRAMEF7 AMFR PRAMEF5 PRAMEF12 PRAMEF8 YEATS2 FBH1 AGO3 ANAPC1 DROSHA MMS19 PRAMEF6 ARMC8	1.27e-03	972	106	13	GO:0140535
MousePheno	abnormal jejunum morphology	PRAMEF7 PRAMEF5 GPX1 PRAMEF12 PRAMEF8 PRAMEF6	1.49e-07	41	84	6	MP:0004002
MousePheno	abnormal spermatogonia proliferation	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 CIT PRAMEF6	3.46e-07	47	84	6	MP:0002685
MousePheno	abnormal cecum morphology	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 GOT2 PRAMEF6	2.82e-05	99	84	6	MP:0000494
MousePheno	abnormal duodenum morphology	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	4.01e-05	64	84	5	MP:0003271
MousePheno	abnormal lens morphology	PRAMEF7 PRAMEF5 GPX1 BMS1 PRAMEF12 PRAMEF8 PPAT FANCD2 ANAPC1 GLRX PLXNA4 KYNU GOT2 PRAMEF6	6.57e-05	699	84	14	MP:0001303
MousePheno	enlarged urinary bladder	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 DACH2 PRAMEF6	6.88e-05	116	84	6	MP:0011874
MousePheno	increased susceptibility to noise-induced hearing loss	GPX1 SLC1A3 TRPV4	7.26e-05	14	84	3	MP:0004597
MousePheno	cryptophthalmos	FRAS1 FREM1	1.07e-04	3	84	2	MP:0005242
MousePheno	increased cellular sensitivity to oxidative stress	GPX1 WRN SLC1A3 GLRX	1.37e-04	44	84	4	MP:0008412
MousePheno	increased male germ cell apoptosis	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 CIT TAS1R1 PRAMEF6	1.39e-04	189	84	7	MP:0014052
MousePheno	cataract	PRAMEF7 PRAMEF5 GPX1 BMS1 PRAMEF12 PRAMEF8 PPAT PLXNA4 KYNU GOT2 PRAMEF6	1.83e-04	497	84	11	MP:0001304
MousePheno	abnormal large intestine morphology	CYLD PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 FREM1 GOT2 PRAMEF6	2.48e-04	276	84	8	MP:0000489
MousePheno	abnormal anterior eye segment morphology	PRAMEF7 PRAMEF5 GPX1 BMS1 PRAMEF12 PRAMEF8 PPAT FREM1 FANCD2 ANAPC1 GLRX LTN1 PLXNA4 TRPV4 KYNU GOT2 PRAMEF6	2.95e-04	1117	84	17	MP:0005193
MousePheno	abnormal circulating amylase level	WBP2 PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.48e-04	156	84	6	MP:0008804
MousePheno	decreased hematopoietic stem cell number	RASSF2 BCL11A FANCD2 KMT2A	3.76e-04	57	84	4	MP:0004810
Domain	PRAME_family	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	4.58e-08	19	101	5	IPR026271
Pathway	WP_IDO_METABOLIC_PATHWAY	AADAT KYNU GOT2	3.14e-05	11	83	3	M48109
Pubmed	Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 NLRP4 PRAMEF6	2.62e-10	28	107	6	25089626
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	NCAPD3 ACACA WRN BMS1 MYO18A CIT TMEM33 ANAPC1 LTN1 MMS19	7.53e-10	202	107	10	33005030
Pubmed	Differential expression of PRAMEL1, a cancer/testis antigen, during spermatogenesis in the mouse.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.51e-09	17	107	5	23565261
Pubmed	Mouse Pramel1 regulates spermatogonial development by inhibiting retinoic acid signaling during spermatogenesis.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.51e-09	17	107	5	37781892
Pubmed	The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.08e-09	18	107	5	23894331
Pubmed	Pramel15 facilitates zygotic nuclear DNMT1 degradation and DNA demethylation.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.08e-09	18	107	5	39181896
Pubmed	Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.08e-09	18	107	5	12890732
Pubmed	Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.08e-09	18	107	5	29731491
Pubmed	Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.08e-09	18	107	5	14675769
Pubmed	Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.82e-09	19	107	5	28604677
Pubmed	Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.75e-09	20	107	5	26694250
Pubmed	Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.75e-09	20	107	5	16580637
Pubmed	Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.75e-09	20	107	5	21425410
Pubmed	Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	6.33e-09	22	107	5	31729367
Pubmed	Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	8.07e-09	23	107	5	19480014
Pubmed	Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.27e-08	25	107	5	12620990
Pubmed	MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.27e-08	25	107	5	37451217
Pubmed	Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.57e-08	26	107	5	18500982
Pubmed	An abundance of X-linked genes expressed in spermatogonia.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 NLRP4 PRAMEF6	2.90e-08	59	107	6	11279525
Pubmed	Thirteen Ovary-Enriched Genes Are Individually Not Essential for Female Fertility in Mice.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.36e-08	30	107	5	38786026
Pubmed	LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	4.73e-08	32	107	5	37889087
Pubmed	Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	7.57e-08	35	107	5	19389355
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	AMFR BMS1 APLP2 SLC1A3 AKAP8L TMEM33 FANCD2 GK PRMT5 LTN1 VPS13A EIF5 MMS19	1.24e-07	657	107	13	36180527
Pubmed	Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.11e-07	46	107	5	17287250
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	4.76e-07	50	107	5	31806660
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	AMFR BMS1 APLP2 SLC1A3 AKAP8L TMEM33 PRMT5 LTN1 VPS13A EIF5	5.65e-07	408	107	10	33766124
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	WBP2 PRAMEF7 PRAMEF5 PRAMEF12 EDC4 PRAMEF8 NUDC NLRP4 PRAMEF6	8.02e-07	326	107	9	17015433
Pubmed	ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.01e-06	58	107	5	31598710
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CYLD DIS3L GPX1 BCL11A AKAP8L FANCD2 YEATS2 ZNF469 BCL11B AGO3 ANAPC1 DROSHA LTN1 MMS19 UNC5D	1.72e-06	1116	107	15	31753913
Pubmed	Dorsal turning of motor corticospinal axons at the pyramidal decussation requires plexin signaling.	PLXNA3 BCL11B PLXNA4	2.35e-06	9	107	3	18727829
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 AGO3 DROSHA KDR NLRP4 PRAMEF6	6.83e-06	424	107	9	21731673
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	NCAPD3 ACACA U2SURP BMS1 APLP2 EDC4 PPAT PAICS TMEM33 FANCD2 ANAPC1 PRMT5 EIF5 NUDC GOT2 ARMC8	7.48e-06	1425	107	16	30948266
Pubmed	Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia.	DOCK4 CNTNAP5	9.38e-06	2	107	2	20346443
Pubmed	COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein.	BCL11A BCL11B	9.38e-06	2	107	2	12196208
Pubmed	Transcriptional profiling reveals a critical role for tyrosine phosphatase VE-PTP in regulation of VEGFR2 activity and endothelial cell morphogenesis.	PTPRB KDR	9.38e-06	2	107	2	19136612
Pubmed	CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis.	BCL11A BCL11B	9.38e-06	2	107	2	15465497
Pubmed	Overlapping and divergent localization of Frem1 and Fras1 and its functional implications during mouse embryonic development.	FRAS1 FREM1	9.38e-06	2	107	2	17240369
Pubmed	Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML.	PRMT5 KMT2A	9.38e-06	2	107	2	28663579
Pubmed	The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.	BCL11A BCL11B	9.38e-06	2	107	2	11719382
Pubmed	Distinct cytoplasmic domains in Plexin-A4 mediate diverse responses to semaphorin 3A in developing mammalian neurons.	PLXNA3 PLXNA4	9.38e-06	2	107	2	24619647
Pubmed	VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation.	PTPRB KDR	9.38e-06	2	107	2	23575676
Pubmed	Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.	TOPBP1 FANCD2 FBH1 KMT2A MMS19 RPA3	9.54e-06	157	107	6	30686591
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	PRAMEF7 AMFR PRSS2 PRAMEF5 PRAMEF12 PRAMEF8 YEATS2 LTN1 MMS19 PRAMEF6	9.99e-06	564	107	10	21565611
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	NCAPD3 WRN TOPBP1 KIF20B AKAP8L FANCD2 GLRX CENPI RPA3	1.16e-05	453	107	9	29656893
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	PRAMEF7 PRAMEF5 U2SURP PRAMEF12 PRAMEF8 AGO3 PRAMEF6 TDRD12	1.25e-05	347	107	8	16033648
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	NCAPD3 WRN BMS1 TOPBP1 APLP2 EDC4 CIT KIF20B AKAP8L ANAPC1 DROSHA PRMT5 LTN1 EIF5 KMT2A ARMC8	1.38e-05	1497	107	16	31527615
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	AMFR DIS3L SARM1 GPX1 BMS1 MYO18A CIT SLC1A3 AKAP8L FANCD2 LTN1	2.17e-05	754	107	11	33060197
Pubmed	Plexin signaling selectively regulates the stereotyped pruning of corticospinal axons from visual cortex.	PLXNA3 PLXNA4	2.81e-05	3	107	2	18523013
Pubmed	Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2.	PTPRB KDR	2.81e-05	3	107	2	10557082
Pubmed	Gene conversion-like missense mutations in the human cationic trypsinogen gene and insights into the molecular evolution of the human trypsinogen family.	PRSS2 PRSS3P2	2.81e-05	3	107	2	11073713
Pubmed	The origin of trypsin: evidence for multiple gene duplications in trypsins.	PRSS2 PRSS3P2	2.81e-05	3	107	2	9732462
Pubmed	Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.	PPAT PAICS	2.81e-05	3	107	2	26140362
Pubmed	Role of NRF-1 in bidirectional transcription of the human GPAT-AIRC purine biosynthesis locus.	PPAT PAICS	2.81e-05	3	107	2	9108165
Pubmed	Excessive fatty acids activate PRMT5/MDM2/Drosha pathway to regulate miRNA biogenesis and lipid metabolism.	DROSHA PRMT5	2.81e-05	3	107	2	38517158
Pubmed	Regulation of pulmonary fibrosis by chemokine receptor CXCR3.	BCL11A BCL11B	2.81e-05	3	107	2	15254596
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	AMFR NCAPD3 BMS1 EDC4 PAICS AKAP8L TMEM33 FANCD2 PRMT5 LTN1 KMT2A MMS19 NUDC RPA3 ARMC8	3.53e-05	1440	107	15	30833792
Pubmed	ETAA1 acts at stalled replication forks to maintain genome integrity.	WRN FANCD2 RPA3	3.62e-05	21	107	3	27723720
Pubmed	Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c.	BCL11A BCL11B UNC5D	4.18e-05	22	107	3	26182416
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	NCAPD3 ACACA CAPN2 GPX1 ANAPC1 LTN1	5.18e-05	212	107	6	33853758
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	WBP2 ACACA EDC4 PAICS TMEM33 YEATS2 ANAPC1 KMT2A NUDC	5.19e-05	549	107	9	38280479
Pubmed	The role of FREM2 and FRAS1 in the development of congenital diaphragmatic hernia.	FRAS1 FREM1	5.60e-05	4	107	2	29618029
Pubmed	Deficiency of FRAS1-related extracellular matrix 1 (FREM1) causes congenital diaphragmatic hernia in humans and mice.	FRAS1 FREM1	5.60e-05	4	107	2	23221805
Pubmed	Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.	PLXNA3 PLXNA4	5.60e-05	4	107	2	11306810
Pubmed	Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins.	PLXNA3 PLXNA4	5.60e-05	4	107	2	15721238
Pubmed	Frem1 activity is regulated by Sonic hedgehog signaling in the cranial neural crest mesenchyme during midfacial morphogenesis.	FRAS1 FREM1	5.60e-05	4	107	2	36495293
Pubmed	PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.	PLXNA3 PLXNA4	5.60e-05	4	107	2	25518740
Pubmed	DICER- and AGO3-dependent generation of retinoic acid-induced DR2 Alu RNAs regulates human stem cell proliferation.	EDC4 AGO3	5.60e-05	4	107	2	23064648
Pubmed	Thermal stability, pH dependence and inhibition of four murine kynurenine aminotransferases.	AADAT GOT2	5.60e-05	4	107	2	20482848
Pubmed	Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.	FRAS1 FREM1	5.60e-05	4	107	2	18563433
Pubmed	Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6-dependent pathway.	BCL11A BCL11B	5.60e-05	4	107	2	35766181
Pubmed	Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing.	DROSHA KMT2A	5.60e-05	4	107	2	17581865
Pubmed	Isolation of a novel family of C(2)H(2) zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors.	BCL11A BCL11B	5.60e-05	4	107	2	10744719
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	WBP2 U2SURP EDC4 PAICS DROSHA PRMT5	6.35e-05	220	107	6	24550385
Pubmed	The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase.	ACACA DIS3L MYO18A PAICS TMEM33 BGN MMS19 NUDC	8.24e-05	453	107	8	27113764
Pubmed	Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature.	PTPRB KDR	9.32e-05	5	107	2	28542220
Pubmed	Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.	FRAS1 FREM1	9.32e-05	5	107	2	17251066
Pubmed	Novel frem1-related mouse phenotypes and evidence of genetic interactions with gata4 and slit3.	FRAS1 FREM1	9.32e-05	5	107	2	23536828
Pubmed	Physical and functional mapping of the replication protein a interaction domain of the werner and bloom syndrome helicases.	WRN RPA3	9.32e-05	5	107	2	15965237
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	FRAS1 FREM1	9.32e-05	5	107	2	17596926
Pubmed	High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.	DOCK4 PLXNA4 UPP2	1.08e-04	30	107	3	19401682
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	WBP2 PRAMEF7 AMFR PRAMEF5 PRAMEF12 EDC4 PRAMEF8 CIT AGO3 PRMT5 VPS13A EEF1AKMT1 PRAMEF6	1.17e-04	1242	107	13	30973865
Pubmed	Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.	PRSS2 TOPBP1 FANCD2	1.20e-04	31	107	3	19690177
Pubmed	Human transcription factor protein interaction networks.	CYLD DIS3L BMS1 MYO18A BCL11A EDC4 CIT AKAP8L YEATS2 AGO3 KMT2A USP27X NUDC RPA3	1.26e-04	1429	107	14	35140242
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	CYLD PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 SLC1A3 PAICS LTN1 ITPRIP NLRP4 PRAMEF6 ARMC8	1.29e-04	1084	107	12	11544199
Pubmed	Secreted semaphorins control spine distribution and morphogenesis in the postnatal CNS.	PLXNA3 PLXNA4	1.40e-04	6	107	2	20010807
Pubmed	Mild recessive mutations in six Fraser syndrome-related genes cause isolated congenital anomalies of the kidney and urinary tract.	FRAS1 FREM1	1.40e-04	6	107	2	24700879
Pubmed	Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals.	PLXNA3 PLXNA4	1.40e-04	6	107	2	20445064
Pubmed	The Amyloid Precursor Protein Is a Conserved Receptor for Slit to Mediate Axon Guidance.	APLP2 BCL11B	1.40e-04	6	107	2	28785723
Pubmed	Craniofacial consequences of connective tissue disorders in mice.	FRAS1 FREM1	1.40e-04	6	107	2	6391574
Pubmed	Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor.	PTPRB KDR	1.40e-04	6	107	2	25644401
Pubmed	Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.	BCL11A BCL11B	1.40e-04	6	107	2	23644491
Pubmed	Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed.	PPAT PAICS	1.40e-04	6	107	2	8106516
Pubmed	Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.	FRAS1 FREM1	1.40e-04	6	107	2	17462874
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	ACACA CAPN2 GPX1 EDC4 PPAT PAICS FANCD2 PRMT5 EIF5 MMS19 GMPPB NUDC RPA3 KYNU	1.52e-04	1455	107	14	22863883
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PRSS2 NCAPD3 FRAS1 AKAP8L TMEM33 PRSS3P2 DROSHA KMT2A KYNU	1.86e-04	650	107	9	38777146
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CYLD BCL11A EDC4 CIT SLC1A3 CNTNAP5 BCL11B AGO3 ANAPC1 UNC79 ARMC8	1.91e-04	963	107	11	28671696
Pubmed	Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration.	SLC1A3 GOT2	1.95e-04	7	107	2	34450065
Pubmed	Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.	PLXNA3 PLXNA4	1.95e-04	7	107	2	19063725
Pubmed	Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.	PLXNA3 PLXNA4	1.95e-04	7	107	2	19655386
Pubmed	Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members.	APLP2 SLC1A3	1.95e-04	7	107	2	15385965
Interaction	LRRC31 interactions	NCAPD3 ACACA WRN BMS1 MYO18A CIT TMEM33 ANAPC1 LTN1 MMS19	5.55e-08	205	97	10	int:LRRC31
Interaction	PFAS interactions	ACACA PPAT CIT PAICS FANCD2 EIF5 RPA3	1.23e-05	160	97	7	int:PFAS
Cytoband	1p36.21	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.77e-07	63	106	5	1p36.21
GeneFamily	PRAME family	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.25e-08	24	71	5	686
GeneFamily	Taste 2 receptors	TAS2R36 TAS2R20 TAS2R30	4.79e-04	39	71	3	1162
GeneFamily	Plexins	PLXNA3 PLXNA4	5.38e-04	9	71	2	683
GeneFamily	C2 domain containing\|Calpains	CAPN2 CAPN13	1.54e-03	15	71	2	975
GeneFamily	Dyneins, axonemal	DNAH2 DNAH1	1.99e-03	17	71	2	536
GeneFamily	EF-hand domain containing\|Nucleotide excision repair\|Transcription and export complex 2	MMS19 RPA3	2.23e-03	18	71	2	1269
Coexpression	KINNEY_DNMT1_METHYLATION_TARGETS	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	2.16e-07	34	103	5	MM955
Coexpression	SANSOM_APC_TARGETS	PRAMEF7 PRSS2 PRAMEF5 DIS3L PRAMEF12 BCL11A PRAMEF8 PAICS PRAMEF6	5.50e-07	245	103	9	MM735
Coexpression	MORI_SMALL_PRE_BII_LYMPHOCYTE_UP	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PTPRB PRAMEF6	2.50e-06	98	103	6	MM592
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3_UNMETHYLATED	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	3.02e-06	57	103	5	MM1262
Coexpression	KOHOUTEK_CCNT2_TARGETS	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	1.72e-05	81	103	5	MM938
Coexpression	GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_UP	GPX1 APLP2 SLC1A3 KIF20B CENPI GOT2	2.99e-05	151	103	6	M6922
Coexpression	DODD_NASOPHARYNGEAL_CARCINOMA_UP	DOCK4 NCAPD3 FRAS1 U2SURP WRN TOPBP1 PPAT SLC1A3 PAICS KIF20B TMEM33 BGN YEATS2 FBH1 AGO3 ANAPC1 CENPI	3.31e-05	1407	103	17	M14427
Coexpression	HAY_BONE_MARROW_ERYTHROBLAST	NCAPD3 U2SURP WRN PPAT CIT PAICS KIF20B FANCD2 FBH1 KCNH2 PRMT5 GLRX NUDC RPA3 GOT2 ARMC8	3.56e-05	1271	103	16	M39197
Coexpression	INGRAM_SHH_TARGETS_UP	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PAICS PRAMEF6	3.59e-05	156	103	6	MM550
Coexpression	DESCARTES_ORGANOGENESIS_SCHWANN_CELL_PRECURSOR	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	4.32e-05	98	103	5	MM3656
Coexpression	HUANG_GATA2_TARGETS_DN	PRAMEF7 PRAMEF5 PRAMEF12 PRAMEF8 PRAMEF6	4.32e-05	98	103	5	MM942
Coexpression	GAO_LARGE_INTESTINE_24W_C2_MKI67POS_PROGENITOR	NCAPD3 KIF20B BGN PTPRB KDR	8.52e-05	113	103	5	M39153
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	FRAS1 CIT PAICS CAPN13 PLXNA4 TDRD12	3.97e-06	177	105	6	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FREM1 DNAH1 OTOGL UNC79 UNC5D	4.96e-06	184	105	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FREM1 DNAH1 OTOGL UNC79 UNC5D	4.96e-06	184	105	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FREM1 DNAH1 OTOGL UNC79 UNC5D	4.96e-06	184	105	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	WRN KIF20B BCL11B VPS13A KMT2A TAS2R30	6.92e-06	195	105	6	4b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	NCAPD3 CIT KIF20B FANCD2 BCL11B CENPI	6.92e-06	195	105	6	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	Control-Myeloid\|Control / Disease state, Lineage and Cell class	DOCK4 GPX1 APLP2 SLC1A3 GK KYNU	6.92e-06	195	105	6	46ce2e403ca5d757e5ba17349b6c7ce5cde1f195
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CIT PAICS KIF20B FANCD2 CENPI RPA3	6.92e-06	195	105	6	56d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TOPBP1 CIT KIF20B FANCD2 CENPI RPA3	7.12e-06	196	105	6	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CYLD FRAS1 BCL11B VPS13A KMT2A TAS2R30	7.33e-06	197	105	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	IPF-Myeloid-Macrophage\|IPF / Disease state, Lineage and Cell class	DOCK4 GPX1 APLP2 SLC1A3 GK KYNU	7.33e-06	197	105	6	a2ffb33c7cad6be43cbb8ed9a91338923cc07db4
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-T/NK_proliferative\|COVID-19_Severe / Disease, condition lineage and cell class	NCAPD3 TOPBP1 CIT PAICS FANCD2 RPA3	7.99e-06	200	105	6	0892603e604c2a945dd720685d45970f855bd5d3
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal-Neurons\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	WBP2 RASSF2 BCL11A BCL11B GLRX UNC79	7.99e-06	200	105	6	ddac952ad1d46021c2d17d816de9bc31730a0941
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	NCAPD3 TOPBP1 CIT PAICS FANCD2 RPA3	7.99e-06	200	105	6	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	NCAPD3 TOPBP1 CIT PAICS FANCD2 RPA3	7.99e-06	200	105	6	9775ca7dedb76fcbb74f80f86b33c94e394c320a
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 BPIFB3 ASIC5 CNTNAP5 OTOGL	2.42e-05	145	105	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	LPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIK3AP1 PPAT GK CENPI KYNU	3.87e-05	160	105	5	5d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FRAS1 ASIC5 CNTNAP5 OTOGL UNC5D	4.11e-05	162	105	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	LPS-antiTNF-Endothelial-Endothelial-FOXM1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCAPD3 CIT KIF20B FANCD2 PTPRB	4.23e-05	163	105	5	5285318c52aa31c9b22dc2ffff078e32e408604d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RASSF2 SLC1A3 GK KYNU	4.88e-05	168	105	5	61a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RASSF2 SLC1A3 GK KYNU	4.88e-05	168	105	5	26fce414439ccd204e3acb41f2b4f75072df5a26
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DNAH1 OTOGL PLXNA4 UNC79	5.02e-05	169	105	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 RASSF2 BCL11A PLXNA4 NLRP4	5.31e-05	171	105	5	af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCell	390C-Endothelial_cells-Endothelial-E-\|390C / Donor, Lineage, Cell class and subclass (all cells)	DAND5 MYO18A PTPRB KDR UNC79	6.43e-05	178	105	5	804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell	390C-Endothelial_cells-Endothelial-E\|390C / Donor, Lineage, Cell class and subclass (all cells)	DAND5 MYO18A PTPRB KDR UNC79	6.43e-05	178	105	5	ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 PTPRB PLXNA4 KDR MMS19	6.60e-05	179	105	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	WRN KIF20B BCL11B VPS13A KMT2A	6.95e-05	181	105	5	986c036e656f24fe374807e2711cec9e3c83c892
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DOCK4 SLC1A3 FREM1 BGN RND3	7.14e-05	182	105	5	ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ZNF469 PTPRB ITPRIP KDR	7.32e-05	183	105	5	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 ZNF469 PTPRB ITPRIP KDR	7.32e-05	183	105	5	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP\|bone_marrow / Manually curated celltypes from each tissue	PAICS FREM1 CNTNAP5 KCNH2 AADAT	7.51e-05	184	105	5	b81a2a95944cee8fec13d63dc0d95496e67aa937
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 PRSS2 PTPRB ITPRIP KDR	7.51e-05	184	105	5	a12a6a481e78adc62da1904431f62b119f70b15f
ToppCell	droplet-Liver-HEPATOCYTES-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BGN PTPRB AGO3 ITPRIP KDR	7.71e-05	185	105	5	742350093d90f96735dc73e3360cdd749bae63fd
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	BCL11A CIT KIF20B FANCD2 CENPI	7.71e-05	185	105	5	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BGN RND3 DACH2 KCNH2 PLXNA4	8.53e-05	189	105	5	f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCell	CTRL-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	PIK3AP1 RASSF2 DRAM2 BCL11A KYNU	8.53e-05	189	105	5	14f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCell	Control-Endothelial-Endothelial-FOXM1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NCAPD3 CIT KIF20B FANCD2 CENPI	8.53e-05	189	105	5	1e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GCNT1 BGN PTPRB PLXNA4 TRPV4	8.74e-05	190	105	5	3b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SDSL GCNT1 BGN PLXNA4 TRPV4	8.74e-05	190	105	5	3cf464664d6aa22b212e60b70885953887e92483
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CIT FANCD2 PTPRB DACH2 CENPI	8.74e-05	190	105	5	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NCAPD3 CIT KIF20B FANCD2 CENPI	8.74e-05	190	105	5	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NCAPD3 CIT KIF20B BCL11B CENPI	8.96e-05	191	105	5	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TNFSF18 BGN DACH2 KCNH2 PLXNA4	9.18e-05	192	105	5	7ae3e1ca8bfc078c0e12a1595ecb0e343dab5d2f
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	PAICS FREM1 BGN RND3 DACH2	9.18e-05	192	105	5	4c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCell	COPD-Myeloid\|COPD / Disease state, Lineage and Cell class	GPX1 APLP2 SLC1A3 GK KYNU	9.41e-05	193	105	5	f58552e286aa27e592497ad78776f58f8ee09841
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NCAPD3 CIT KIF20B FANCD2 CENPI	9.41e-05	193	105	5	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 RASSF2 GCNT1 SLC1A3 KYNU	9.41e-05	193	105	5	bd08555f02db8bc903caacae57e80bb91e2556ce
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 RASSF2 GCNT1 SLC1A3 KYNU	9.41e-05	193	105	5	f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3AP1 RASSF2 GCNT1 SLC1A3 KYNU	9.41e-05	193	105	5	374d0526a071e973c3f43b4564f78f6933bb67ed
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NCAPD3 CIT KIF20B FANCD2 CENPI	9.64e-05	194	105	5	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	Control-Myeloid-TRAM2\|Control / Condition, Lineage and Cell class	CAPN2 SLC1A3 RND3 GK KYNU	9.64e-05	194	105	5	d951dd1274d3ff1ac30671ec4153a4a8bc97b53f
ToppCell	IIH-mono3-\|IIH / Condition, Cell_class and T cell subcluster	DOCK4 TNFSF18 SLC1A3 GK NLRP4	9.87e-05	195	105	5	28a858b04a7b413916c07a8d880f5ea02e985461
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CIT KIF20B FANCD2 CENPI RPA3	9.87e-05	195	105	5	cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	DOCK4 PIK3AP1 SLC1A3 GK KYNU	9.87e-05	195	105	5	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 BCL11A DACH2 TRPV4 UPP2	9.87e-05	195	105	5	6c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CIT KIF20B FANCD2 CENPI RPA3	9.87e-05	195	105	5	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SDSL GPX1 SLC1A3 GK KYNU	9.87e-05	195	105	5	ef2304acb01638df197f42dcc3db8c5867f4dc17
ToppCell	IPF-Myeloid\|IPF / Disease state, Lineage and Cell class	GPX1 APLP2 SLC1A3 GK KYNU	9.87e-05	195	105	5	fdeb958aeaa00f3fc25c4e59efbbc6f4a572c9ce
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SDSL GPX1 SLC1A3 GK KYNU	9.87e-05	195	105	5	5ed495941b80221206b8a9a86d92221ab8ba6682
ToppCell	IIH-mono3\|IIH / Condition, Cell_class and T cell subcluster	DOCK4 TNFSF18 SLC1A3 GK NLRP4	9.87e-05	195	105	5	c6dd5af582d257be64b718e30f60220c1bf1738a
ToppCell	11.5-Distal-Mesenchymal-Airway_Smooth_Muscle\|Distal / Age, Tissue, Lineage and Cell class	BCL11A BGN DACH2 KCNH2 PLXNA4	1.01e-04	196	105	5	05530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	CIT SLC1A3 KIF20B FANCD2 CENPI	1.01e-04	196	105	5	5905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	CIT KIF20B BGN FANCD2 CENPI	1.01e-04	196	105	5	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NCAPD3 CIT KIF20B FANCD2 CENPI	1.01e-04	196	105	5	1964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCell	Control-Myeloid-Macrophage\|Control / Disease state, Lineage and Cell class	DOCK4 GPX1 SLC1A3 GK KYNU	1.01e-04	196	105	5	e2c2a30fa3ee3034fbde5335be169e880dde622d
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	DOCK4 RASSF2 SLC1A3 GK KYNU	1.01e-04	196	105	5	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	COVID-19-lung-Proliferative_fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CIT KIF20B BGN FANCD2 CENPI	1.01e-04	196	105	5	ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAPD3 CIT KIF20B PTPRB CENPI	1.01e-04	196	105	5	0644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 RASSF2 SLC1A3 GK KYNU	1.04e-04	197	105	5	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NCAPD3 CIT KIF20B FANCD2 CENPI	1.04e-04	197	105	5	84ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PIK3AP1 SLC1A3 CNTNAP5 GK KYNU	1.04e-04	197	105	5	61bda9b5102fdbce902bb976d1aa62f2c799d2fb
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK4 PIK3AP1 SLC1A3 GK KYNU	1.04e-04	197	105	5	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 BCL11A DACH2 TRPV4 UPP2	1.04e-04	197	105	5	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NCAPD3 CIT KIF20B PTPRB KDR	1.04e-04	197	105	5	a41420d4b6d502c2f594c054c7efbb5d4eac83ff
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK4 PIK3AP1 RASSF2 GK KYNU	1.04e-04	197	105	5	1eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCell	distal-2-Hematologic-Alveolar_Macrophage\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIK3AP1 SLC1A3 GK GLRX KYNU	1.06e-04	198	105	5	a8093144cbe3069c25a6c1f1c94218a115da8748
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	DOCK4 PIK3AP1 SLC1A3 GK KYNU	1.06e-04	198	105	5	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	distal-Hematologic-Proliferating_Macrophage-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	NCAPD3 CIT KIF20B FANCD2 CENPI	1.06e-04	198	105	5	8afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GPX1 APLP2 SLC1A3 GK KYNU	1.06e-04	198	105	5	76db943db8b5483754f38e4c6af7f5955cec420c
ToppCell	COVID-19-kidney-Macrophages\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK4 PIK3AP1 SLC1A3 GK KYNU	1.06e-04	198	105	5	161324541fe5da5cbb58142ea94fefd39b7dfb04
ToppCell	COVID-19-Myeloid-Alveolar_macrophages\|COVID-19 / group, cell type (main and fine annotations)	PIK3AP1 APLP2 SLC1A3 GK KYNU	1.09e-04	199	105	5	e1c85ca85fa22c4a4fa1bbdf55304bf3628485ee
ToppCell	HSPCs\|World / Lineage and Cell class	GPX1 PPAT PAICS NUDC RPA3	1.09e-04	199	105	5	df1ffc416c6946f1ba182f242a50ee41a571d565
ToppCell	5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCL11A GCNT1 PAICS FREM1 CAPN13	1.09e-04	199	105	5	f544229f471b4717166dd4b588399afe45cc31b5
ToppCell	COPD-Myeloid-Macrophage\|COPD / Disease state, Lineage and Cell class	DOCK4 GPX1 SLC1A3 GK KYNU	1.09e-04	199	105	5	4b9c53fb4f44190d2f6ad4d52b13be01ebe4955e
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GPX1 APLP2 SLC1A3 GK KYNU	1.09e-04	199	105	5	bcf7d15b6a08b24e7dd0ce106817659cb976f833
ToppCell	COVID-19_Severe-Lymphoid_T/NK-T/NK_proliferative\|COVID-19_Severe / Disease group, lineage and cell class	NCAPD3 TOPBP1 CIT FANCD2 RPA3	1.09e-04	199	105	5	ddae7fe7633661f15d3c79f5187415ffbfecce67
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	RASSF2 BCL11A BCL11B GLRX UNC79	1.11e-04	200	105	5	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	BCL11A RND3 BCL11B GLRX PLXNA4	1.11e-04	200	105	5	84e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DOCK4 SLC1A3 FREM1 RND3 PLXNA4	1.11e-04	200	105	5	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	BCL11A RND3 BCL11B GLRX PLXNA4	1.11e-04	200	105	5	1decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCell	mLN-(2)_B_cell-(23)_Follicular_B_cell\|mLN / shred on region, Cell_type, and subtype	PIK3AP1 APLP2 DRAM2 BCL11A GCNT1	1.11e-04	200	105	5	659b49eeeb3e96b0a52663e60336ca4d76c83cfc
ToppCell	Parenchyma_COVID-19-Immune-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	PIK3AP1 SLC1A3 GK GLRX KYNU	1.11e-04	200	105	5	fe27d56a05151049a64e35db5a144ff7952e6902
ToppCell	mLN-B_cell-Follicular_B_cell\|mLN / Region, Cell class and subclass	PIK3AP1 APLP2 DRAM2 BCL11A GCNT1	1.11e-04	200	105	5	7f5dbd06f8643230dba45d6fa0258a13cb71f681
ToppCell	Severe-T/NK_proliferative\|Severe / Disease group and Cell class	NCAPD3 TOPBP1 PAICS KIF20B RPA3	1.11e-04	200	105	5	4723613a9f56bff422fc98722128d57b6adf3c5d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NCAPD3 CIT KIF20B FANCD2 CENPI	1.11e-04	200	105	5	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Glia_progenitor_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	PIK3AP1 SDSL SARM1 ZNF469 PRMT5	1.11e-04	200	105	5	4b937b1d0179d1d0e51931f35720e205d460a07e
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NCAPD3 TOPBP1 CIT FANCD2 CENPI	1.11e-04	200	105	5	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-5\|TCGA-Stomach / Sample_Type by Project: Shred V9	PRAMEF7 DNAH2 PRAMEF12 TDRD12	1.16e-04	106	105	4	4bee154c8b984338c06f73bd6e3fb26abce0bd72
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK4 RASSF2 EDC4 FBH1	2.32e-04	127	105	4	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	Cerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	ASIC5 BCL11B KCNA7 UNC5D	2.54e-04	130	105	4	ab141d91988a5de6d092757377a53f7de3707556
Computational	Genes in the cancer module 177.	DPH1 BGN PRMT5 GLRX EIF5 KYNU	9.52e-06	101	53	6	MODULE_177
Computational	Neighborhood of RAD54L	BMS1 KIF20B MMS19 NUDC GOT2	1.60e-04	105	53	5	MORF_RAD54L
Disease	breast angiosarcoma (is_implicated_in)	PTPRB KDR	3.07e-05	3	95	2	DOID:4511 (is_implicated_in)
Disease	corneal hysteresis	ABCA10 ZNF469 ANAPC1	3.54e-05	20	95	3	EFO_0010066
Disease	Fraser syndrome (implicated_via_orthology)	FRAS1 FREM1	6.13e-05	4	95	2	DOID:0090001 (implicated_via_orthology)
Disease	brain glioma (is_marker_for)	PTPRB KDR	1.02e-04	5	95	2	DOID:0060108 (is_marker_for)
Disease	glutamate measurement	SLC1A3 GLRX UNC5D	1.11e-04	29	95	3	EFO_0010487
Disease	neurodegenerative disease (biomarker_via_orthology)	APLP2 GOT2	1.53e-04	6	95	2	DOID:1289 (biomarker_via_orthology)
Disease	epilepsy (implicated_via_orthology)	CIT SLC1A3 KCNA7 KCNH2 NUDC	1.88e-04	163	95	5	DOID:1826 (implicated_via_orthology)
Disease	hemoglobin subunit zeta measurement	SARM1 BCL11A	2.13e-04	7	95	2	EFO_0801670
Disease	Unilateral agenesis of kidney	FRAS1 FREM1	2.84e-04	8	95	2	C0266294
Disease	Malignant Head and Neck Neoplasm	CYLD GPX1 FANCD2	3.89e-04	44	95	3	C0278996
Disease	thyroid gland carcinoma (is_marker_for)	PTPRB KDR	6.63e-04	12	95	2	DOID:3963 (is_marker_for)
Disease	Spondyloepiphyseal Dysplasia	TRPV4 KDR	1.20e-03	16	95	2	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	TRPV4 KDR	1.20e-03	16	95	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	TRPV4 KDR	1.20e-03	16	95	2	C4551479
Disease	sickle cell anemia (is_implicated_in)	GPX1 BCL11A	1.20e-03	16	95	2	DOID:10923 (is_implicated_in)
Disease	Schwartz-Jampel Syndrome	TRPV4 KDR	1.20e-03	16	95	2	C0036391
Disease	Melnick-Needles Syndrome	TRPV4 KDR	1.20e-03	16	95	2	C0025237
Disease	neurodegenerative disease (implicated_via_orthology)	SARM1 BCL11A SLC1A3 BCL11B	1.26e-03	145	95	4	DOID:1289 (implicated_via_orthology)
Disease	non-Hodgkin lymphoma (is_implicated_in)	GPX1 KMT2A	1.35e-03	17	95	2	DOID:0060060 (is_implicated_in)
Disease	Van Buchem disease	TRPV4 KDR	1.35e-03	17	95	2	C0432272
Disease	Hemangiosarcoma	PTPRB KDR	1.52e-03	18	95	2	C0018923
Disease	Osteochondrodysplasias	TRPV4 KDR	1.69e-03	19	95	2	C0029422
Disease	Dyschondroplasias	TRPV4 KDR	1.69e-03	19	95	2	C0013366
Disease	Multiple Epiphyseal Dysplasia	TRPV4 KDR	1.88e-03	20	95	2	C0026760
Disease	lung non-small cell carcinoma (is_marker_for)	GPX1 BCL11A PTPRB KDR	2.21e-03	169	95	4	DOID:3908 (is_marker_for)
Disease	Autosomal Recessive Primary Microcephaly	NCAPD3 CIT	2.27e-03	22	95	2	C3711387
Disease	Myocardial Ischemia	APLP2 PPAT GK KDR	2.55e-03	176	95	4	C0151744
Disease	glioblastoma (is_implicated_in)	PTPRB KDR	2.70e-03	24	95	2	DOID:3068 (is_implicated_in)
Disease	Acute monocytic leukemia	FANCD2 KMT2A	3.17e-03	26	95	2	C0023465

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCKVFEMIINPGDNV	AADAT	121	Q8N5Z0
VVEQMLFKVLPGLLC	BPIFB3	181	P59826
NTKKLNCFPVLMGIV	ABCA10	886	Q8WWZ4
EPNFMLFEKCEVNGA	GPX1	106	P07203
LKDNTCVVEFQFMLP	ACACA	1171	Q13085
QQKFIAMFICSEIPI	CAPN13	321	Q6MZZ7
MGKPIKLLANCFQVE	AGO3	26	Q9H9G7
KVALQMPEGLLLFAC	DPH1	76	Q9BZG8
AANPVEFMCQAFKIV	PIK3AP1	276	Q6ZUJ8
EFLNICQVHGFPKIM	BMS1	166	Q14692
FLMDGQELICLPQVF	DACH2	81	Q96NX9
FVLFEECSQPALMKI	CIT	56	O14578
ACDLFIPMQFGIIQK	AKAP8L	486	Q9ULX6
ILQGPCEQISKVFLM	RASSF2	246	P50749
VVLPAFEKSCQAMFQ	EDC4	1121	Q6P2E9
GKFMPFNLIPVIQCD	ITPRIP	341	Q8IWB1
FLIGFCEILQKMNIT	LTN1	1046	O94822
RGLFMNSEFLPVVKC	ANAPC1	1836	Q9H1A4
AVAEPQIAMFCGKLN	APLP2	46	Q06481
VIQGMCKAVPFVQVF	DAND5	96	Q8N907
CPIKINQFEGHFMKL	PTPRB	1681	P23467
EFQLCNNEKVFLMDP	FRAS1	3661	Q86XX4
DKQLCEFFGIPMEIL	GK3P	216	Q14409
PLNGFKDQLCSLVFM	MMS19	436	Q96T76
PLQIFDKICLNILFM	LIPJ	216	Q5W064
QPKDFLTGMCLFLQS	GMPPB	221	Q9Y5P6
IDMNAVLKGFPECLQ	KCNH2	711	Q12809
CQMNFPLGDILIFIE	BCL11A	51	Q9H165
MKFLTCTQGPQEGLF	PNMA6F	341	A0A0J9YX94
VINDTAMLCKAPGIF	PLXNA3	1071	P51805
EPLFSLFCAIKQQME	PLXNA4	1456	Q9HCM2
LFCAIKQQMEKGPID	PLXNA4	1461	Q9HCM2
VIHQFFCDVPQMLKL	OR14J1	171	Q9UGF5
NITKVGVNDFCPMGF	BGN	311	P21810
PEKCLFGAMLNIAAV	DRAM2	51	Q6UX65
PNQIPKAAFMAVFIL	FREM1	291	Q5H8C1
KEFFQGCIMQPVKDL	KIF20B	126	Q96Q89
QAAELLGVKMCTFVP	EEF1AKMT1	176	Q8WVE0
CLFEMQDPAFVKQAV	NLRP4	556	Q96MN2
TNFPVLIQFVNGMKC	OC90	71	Q02509
GQQPLMVILDLCFKN	PRAMEF12	141	O95522
FKNLVDINFVCAMGP	DNAH1	2331	Q9P2D7
MQALKCFSVLAFENP	ARMC8	206	Q8IUR7
QDMLDGFIKKFVLCP	EIF5	86	P55010
IMNIVLSQPCGKIFV	FBH1	656	Q8NFZ0
CPSKAIFFKNVMNLI	KCNA7	231	Q96RP8
CQMNFPLGDILVFIE	BCL11B	61	Q9C0K0
NACVKNKGQFEMVIP	DOCK4	66	Q8N1I0
PELKGIIFMQTACQA	DIS3L	76	Q8TF46
NMFPPNLVEACFKQF	SLC1A3	176	P43003
MAQEFVNCKIQPGKV	GLRX	1	P35754
DKQLCEFFGIPMEIL	GK	216	P32189
GAVAKQGFDFLCMPV	PRMT5	31	O14744
VEKMEFPAVTFCNLN	ASIC5	101	Q9NY37
CGNILPSDIMDFVLK	KMT2A	2841	Q03164
VPFVNGVLFCKMRLL	FAM102B	21	Q5T8I3
FGNAVNTRILKCMIP	CENPI	121	Q92674
CLIIQMPRFGKDFKL	CYLD	751	Q9NQC7
LCGMDFPIKTNLEIV	GCNT1	216	Q02742
FKMPCQLHQVIVARF	CAPN2	636	P17655
CFGLKLELGMPVQTQ	DNAH2	121	Q9P225
ILFFVLNDMGCIDPM	DNAH2	3616	Q9P225
RQQPFMVFIDLCLKN	PRAMEF8	141	Q5VWM4
AMFSCIVNFQLPKEE	SPACA6	166	W5XKT8
IKAFQGCMRLIFIDN	CNTNAP5	506	Q8WYK1
GCMRLIFIDNQPKDL	CNTNAP5	511	Q8WYK1
FVEAFLKQCMPLLDF	FANCD2	1301	Q9BXW9
MPAFEAIFFKCQILL	OTOGL	311	Q3ZCN5
IQEFCPNTKMLLVGC	RND3	121	P61587
FFCDILPVMKLSCIN	OR10J6P	176	Q8NGY7
PKEIVLMLCQAFGII	TAS2R20	256	P59543
NFGRLEKQPVFMFCQ	TAS2R30	251	P59541
EKQPVFMFCQAIIFS	TAS2R30	256	P59541
NFGRLEKQPVFMFCQ	TAS2R36	251	P0DTE0
EKQPVFMFCQAIIFS	TAS2R36	256	P0DTE0
NLPAMFGDVKFVCVG	UPP2	51	O95045
MPENFCVKGLELFSL	DROSHA	636	Q9NRR4
PLKITSNMFCVGFLE	PRSS3P2	176	Q8NHM4
FPNKVVLMCIIINGL	SLC35F5	391	Q8WV83
MLQLLVLKIEDPGCF	TDRD12	1	Q587J7
VLQLKMSNIPACFLG	WRN	606	Q14191
MLAQFIDKPVCFVGR	RPA3	16	P35244
PFCVNFRLKGKDMVV	NUDC	186	Q9Y266
LSQVAGMPVFLKCEN	SDSL	26	Q96GA7
PRKNDIGDAMVFCLN	U2SURP	551	O15042
DQIGMFCFTGLKPEQ	GOT2	376	P00505
MLVAKLIQCIVFGPL	AMFR	96	Q9UKV5
KRNPVMFFQHFIECI	NCAPD3	1046	P42695
LPQNCTLVDMKIEFG	PAICS	181	P22234
RQQPFMVFIDLCLKN	PRAMEF7	141	Q5VXH5
KMPCLEAFQAVLDGL	PRAMEF6	71	Q5VXH4
QLTMNKLPVVACFHF	USP27X	296	A6NNY8
EVPCFNVNAQLKPME	VPS13A	1306	Q96RL7
GICIAFKDIMPFSAQ	TAS1R1	236	Q7RTX1
NFVLVLSPGALDKCM	SARM1	616	Q6SZW1
LGFNVTLPPFMCNKQ	SSX8P	61	Q7RTT4
FIFLQLETAKEPCMA	TNFSF18	46	Q9UNG2
KMPCLEAFQAVLDGL	PRAMEF5	71	Q5TYX0
CFMGINIPTKEELIA	PPAT	426	Q06203
FCEPLQLSMKGIDVF	ZBED8	206	Q8IZ13
PGKITNNMFCVGFLE	PRSS2	176	P07478
KARPAMQIFFKCNGE	UNC5D	76	Q6UXZ4
LSTKFEMQDLCFLGP	ZNF469	3021	Q96JG9
MFPVFSGCFQELQEK	ZNF717	1	Q9BY31
PLMVIVEFCKFGNLS	KDR	911	P35968
NMEDFKCPIFLGCII	TOPBP1	191	Q92547
VMCNDLFKVNPFQLQ	MYO18A	71	O95411
DLFMKKCPGVNSLFI	TRPV4	531	Q9HBA0
ILKFIACNEIFLMPA	TMEM33	156	P57088
ICNIPFLDFLTNKHM	YEATS2	1401	Q9ULM3
CQKRDQLFVPIMFAL	TARM1	146	B6A8C7
GFQFPKPEMICQLEN	ZNF789	51	Q5FWF6
FEEPDILFNMLNCLK	UNC79	966	Q9P2D8
LMKDCEIKQPVFGAN	WBP2	76	Q969T9
MDNKLQLIPGVCGFR	KYNU	316	Q16719