Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glutathione binding	GSTM1 GSTM2 GSTM4 GSTM5	1.28e-06	18	93	4	GO:0043295
GeneOntologyMolecularFunction	oligopeptide binding	GSTM1 GSTM2 GSTM4 GSTM5	2.02e-06	20	93	4	GO:1900750
GeneOntologyMolecularFunction	glutathione transferase activity	GSTM1 GSTM2 GSTM4 GSTM5	9.58e-06	29	93	4	GO:0004364
GeneOntologyMolecularFunction	transferase activity, transferring alkyl or aryl (other than methyl) groups	GSTM1 GSTM2 GSTM4 GSTM5 COQ2	1.21e-05	64	93	5	GO:0016765
GeneOntologyMolecularFunction	phosphatidate cytidylyltransferase activity	CDS1 CDS2	6.42e-05	3	93	2	GO:0004605
GeneOntologyMolecularFunction	serine-type endopeptidase inhibitor activity	CD109 SERPINA10 SERPINA6 SERPIND1 RECK	1.32e-04	105	93	5	GO:0004867
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A7 TOMM7 SLC29A3 SLC11A1 MFSD14B SLC43A1 ABCB11 BEST3 ABCC9 CTNS GRIN2C SPNS3 ABCA10 NDUFC1 SLC37A4	3.46e-04	1180	93	15	GO:0022857
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A7 SLC29A3 SLC11A1 ABCB11 ABCC9 CTNS ABCA10 NDUFC1 SLC37A4	3.83e-04	477	93	9	GO:0022804
GeneOntologyMolecularFunction	transporter activity	SLC6A7 TOMM7 SLC29A3 SLC11A1 MFSD14B SLC43A1 ABCB11 BEST3 ABCC9 CTNS GRIN2C SPNS3 ABCA10 NDUFC1 SLC37A4	8.68e-04	1289	93	15	GO:0005215
GeneOntologyMolecularFunction	cytidylyltransferase activity	CDS1 CDS2	9.42e-04	10	93	2	GO:0070567
GeneOntologyMolecularFunction	acetylglucosaminyltransferase activity	PIGQ MGAT3 MGAT5	1.37e-03	47	93	3	GO:0008375
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A7 SLC43A1 CTNS GRIN2C	1.47e-03	105	93	4	GO:0015171
GeneOntologyMolecularFunction	endopeptidase inhibitor activity	CD109 SERPINA10 SERPINA6 SERPIND1 RECK	1.54e-03	180	93	5	GO:0004866
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCB11 ABCC9 ABCA10	1.54e-03	49	93	3	GO:0140359
GeneOntologyBiologicalProcess	nitrobenzene metabolic process	GSTM1 GSTM2 GSTM4	3.42e-07	4	92	3	GO:0018916
GeneOntologyBiologicalProcess	glutathione metabolic process	GSTM1 GSTM2 GSTM4 GSTM5 CTNS	9.07e-06	63	92	5	GO:0006749
GeneOntologyBiologicalProcess	xenobiotic catabolic process	GSTM1 GSTM2 GSTM4 GSTM5	2.19e-05	37	92	4	GO:0042178
GeneOntologyBiologicalProcess	lipid droplet formation	CDS1 CDS2 FITM2	3.76e-05	15	92	3	GO:0140042
GeneOntologyBiologicalProcess	xenobiotic metabolic process	GSTM1 GSTM2 GSTM4 GSTM5 SLC29A3 ABCB11	4.04e-05	141	92	6	GO:0006805
GeneOntologyBiologicalProcess	cellular response to xenobiotic stimulus	GSTM1 GSTM2 GSTM4 GSTM5 SLC29A3 ABCB11 ABCC9	6.14e-05	222	92	7	GO:0071466
Domain	GST_mu	GSTM1 GSTM2 GSTM4 GSTM5	2.75e-09	5	92	4	IPR003081
Domain	GST_N	GSTM1 GSTM2 GSTM4 GSTM5	3.77e-06	22	92	4	PF02798
Domain	GST_NTER	GSTM1 GSTM2 GSTM4 GSTM5	3.77e-06	22	92	4	PS50404
Domain	GST_C	GSTM1 GSTM2 GSTM4 GSTM5	7.59e-06	26	92	4	IPR004046
Domain	GST_C	GSTM1 GSTM2 GSTM4 GSTM5	7.59e-06	26	92	4	PF00043
Domain	Glutathione_S-Trfase_N	GSTM1 GSTM2 GSTM4 GSTM5	8.87e-06	27	92	4	IPR004045
Domain	GST_CTER	GSTM1 GSTM2 GSTM4 GSTM5	2.28e-05	34	92	4	PS50405
Domain	PC_trans	CDS1 CDS2	2.40e-05	2	92	2	IPR000374
Domain	CDS	CDS1 CDS2	2.40e-05	2	92	2	PS01315
Domain	PC_Trfase_euk	CDS1 CDS2	2.40e-05	2	92	2	IPR016720
Domain	Glutathione-S-Trfase_C-like	GSTM1 GSTM2 GSTM4 GSTM5	3.97e-05	39	92	4	IPR010987
Domain	-	GSTM1 GSTM2 GSTM4 GSTM5	3.97e-05	39	92	4	1.20.1050.10
Domain	MFS_1	MFSD14B SLC43A1 SPNS3 SLC37A4	5.67e-04	77	92	4	PF07690
Domain	MFS	MFSD14B SLC43A1 SPNS3 SLC37A4	5.67e-04	77	92	4	IPR011701
Domain	Serpin_dom	SERPINA10 SERPINA6 SERPIND1	7.34e-04	36	92	3	IPR023796
Domain	SERPIN	SERPINA10 SERPINA6 SERPIND1	7.96e-04	37	92	3	SM00093
Domain	SERPIN	SERPINA10 SERPINA6 SERPIND1	7.96e-04	37	92	3	PS00284
Domain	Serpin	SERPINA10 SERPINA6 SERPIND1	8.61e-04	38	92	3	PF00079
Domain	Serpin_fam	SERPINA10 SERPINA6 SERPIND1	9.30e-04	39	92	3	IPR000215
Domain	GST_C_3	GSTM1 GSTM4	1.05e-03	10	92	2	PF14497
Domain	ABC_transporter_CS	ABCB11 ABCC9 ABCA10	1.16e-03	42	92	3	IPR017871
Domain	DUF4599	SPATA31D4 SPATA31D3	1.53e-03	12	92	2	PF15371
Domain	DUF4599	SPATA31D4 SPATA31D3	1.53e-03	12	92	2	IPR027970
Domain	ubiquitin	SACS UBLCP1 HERPUD1	1.60e-03	47	92	3	PF00240
Domain	ABC_tran	ABCB11 ABCC9 ABCA10	1.70e-03	48	92	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCB11 ABCC9 ABCA10	1.70e-03	48	92	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCB11 ABCC9 ABCA10	1.81e-03	49	92	3	PS00211
Domain	ABC_transporter-like	ABCB11 ABCC9 ABCA10	1.92e-03	50	92	3	IPR003439
Domain	-	EFNB1 CP	2.10e-03	14	92	2	2.60.40.420
Domain	UBIQUITIN_2	SACS UBLCP1 HERPUD1	2.39e-03	54	92	3	PS50053
Domain	Ubiquitin_dom	SACS UBLCP1 HERPUD1	2.93e-03	58	92	3	IPR000626
Domain	-	GSTM1 GSTM2 GSTM4 GSTM5	3.11e-03	122	92	4	3.40.30.10
Domain	Thioredoxin-like_fold	GSTM1 GSTM2 GSTM4 GSTM5	4.12e-03	132	92	4	IPR012336
Domain	MFS_dom	MFSD14B SLC43A1 SPNS3 SLC37A4	4.35e-03	134	92	4	IPR020846
Domain	Cupredoxin	EFNB1 CP	5.20e-03	22	92	2	IPR008972
Domain	PDZ	LMO7 RIMS1 PREX2 AHNAK2	5.21e-03	141	92	4	PF00595
Domain	PDZ	LMO7 RIMS1 PREX2 AHNAK2	6.17e-03	148	92	4	SM00228
Pathway	KEGG_MEDICUS_ENV_FACTOR_DCE_TO_DNA_ADDUCTS	GSTM1 GSTM2 GSTM4 GSTM5	2.29e-06	19	72	4	M47809
Pathway	KEGG_MEDICUS_ENV_FACTOR_TCDD_TO_AHR_SIGNALING_PATHWAY	GSTM1 GSTM2 GSTM4 GSTM5	5.15e-06	23	72	4	M47806
Pathway	KEGG_MEDICUS_REFERENCE_KEAP1_NRF2_SIGNALING_PATHWAY	GSTM1 GSTM2 GSTM4 GSTM5	6.15e-06	24	72	4	M47487
Pathway	REACTOME_GLUTATHIONE_CONJUGATION	GSTM1 GSTM2 GSTM4 GSTM5	3.26e-05	36	72	4	M1443
Pathway	REACTOME_GLUTATHIONE_CONJUGATION	GSTM1 GSTM2 GSTM4 GSTM5	4.05e-05	38	72	4	MM14600
Pathway	KEGG_GLUTATHIONE_METABOLISM	GSTM1 GSTM2 GSTM4 GSTM5	1.21e-04	50	72	4	M1840
Pathway	WP_GLUTATHIONE_METABOLISM	GSTM1 GSTM2 GSTM5	3.42e-04	27	72	3	MM15908
Pathway	KEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450	GSTM1 GSTM2 GSTM4 GSTM5	4.45e-04	70	72	4	M16794
Pathway	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	GSTM1 GSTM2 GSTM4 GSTM5	4.95e-04	72	72	4	M9257
Pubmed	Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.	GSTM1 GSTM2 GSTM4 GSTM5	2.50e-10	5	94	4	19856098
Pubmed	Glutathione S-transferase variants and hypertension.	GSTM1 GSTM2 GSTM4 GSTM5	2.50e-10	5	94	4	18551009
Pubmed	Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4.	GSTM1 GSTM4 GSTM5	1.91e-08	3	94	3	8471052
Pubmed	Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.	GSTM1 GSTM2 GSTM5	1.91e-08	3	94	3	32574561
Pubmed	Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion.	GSTM1 GSTM2 GSTM5	1.91e-08	3	94	3	9452477
Pubmed	Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution.	GSTM1 GSTM2 GSTM4	1.91e-08	3	94	3	16549767
Pubmed	The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor.	GSTM1 GSTM2 GSTM5	7.63e-08	4	94	3	22406107
Pubmed	Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript.	GSTM1 GSTM2 GSTM4	7.63e-08	4	94	3	8373352
Pubmed	Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.	GSTM1 GSTM2 GSTM5	7.63e-08	4	94	3	8317488
Pubmed	Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function.	GSTM2 GSTM4 GSTM5	7.63e-08	4	94	3	19151192
Pubmed	Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.	GSTM1 GSTM2 GSTM4	3.80e-07	6	94	3	1530570
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	GSTM1 GSTM2 GSTM4 GSTM5 LIPA ABCB11 ABCC9	9.89e-07	193	94	7	19343046
Pubmed	Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.	GSTM1 GSTM2 GSTM4 GSTM5	1.30e-06	30	94	4	20200426
Pubmed	Isolation, characterization, and expression in Escherichia coli of two murine Mu class glutathione S-transferase cDNAs homologous to the rat subunits 3 (Yb1) and 4 (Yb2).	GSTM1 GSTM5	7.23e-06	2	94	2	2689439
Pubmed	Genomic organization and characterization of the promoter region of murine GSTM2 gene.	GSTM1 GSTM5	7.23e-06	2	94	2	11404019
Pubmed	Structure of human glutathione S-transferase class Mu genes.	GSTM2 GSTM4	7.23e-06	2	94	2	2006920
Pubmed	Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.	GSTM1 GSTM4	7.23e-06	2	94	2	3174634
Pubmed	Human genes for glutathione S-transferases.	GSTM1 GSTM2	7.23e-06	2	94	2	6500576
Pubmed	Isolation and characterization of murine Cds (CDP-diacylglycerol synthase) 1 and 2.	CDS1 CDS2	7.23e-06	2	94	2	16023307
Pubmed	Diverse expression of N-acetylglucosaminyltransferase V and complex-type β1,6-branched N-glycans in uveal and cutaneous melanoma cells.	MGAT3 MGAT5	7.23e-06	2	94	2	26098720
Pubmed	Distinct properties of the two isoforms of CDP-diacylglycerol synthase.	CDS1 CDS2	7.23e-06	2	94	2	25375833
Pubmed	Cloning and expression of a novel Mu class murine glutathione transferase isoenzyme.	GSTM2 GSTM4	7.23e-06	2	94	2	12069689
Pubmed	Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2.	GSTM1 GSTM2	7.23e-06	2	94	2	24048194
Pubmed	The role of mannosylated enzyme and the mannose receptor in enzyme replacement therapy.	MRC1 LIPA	7.23e-06	2	94	2	16380916
Pubmed	Pi-class glutathione-S-transferase-positive hepatocytes in aging B6C3F1 mice undergo apoptosis induced by dietary restriction.	GSTM1 GSTM5	7.23e-06	2	94	2	8909248
Pubmed	CDP-DAG synthase 1 and 2 regulate lipid droplet growth through distinct mechanisms.	CDS1 CDS2	7.23e-06	2	94	2	31548309
Pubmed	DNA methylation is associated with altered gene expression in AMD.	GSTM1 GSTM5	7.23e-06	2	94	2	22410570
Pubmed	Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign.	GSTM1 GSTM2	7.23e-06	2	94	2	12486119
Pubmed	Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes.	CDS1 CDS2	7.23e-06	2	94	2	9806839
Pubmed	CDP-diacylglycerol synthases regulate the growth of lipid droplets and adipocyte development.	CDS1 CDS2	7.23e-06	2	94	2	26946540
Pubmed	Quantitative assessment of the effect of glutathione S-transferase genes GSTM1 and GSTT1 on hepatocellular carcinoma risk.	GSTM1 GSTM2	7.23e-06	2	94	2	24399650
Pubmed	The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.	GSTM1 GSTM2	7.23e-06	2	94	2	23675469
Pubmed	Progesterone regulation of glutathione S-transferase Mu2 expression in mouse uterine luminal epithelium during preimplantation period.	GSTM1 GSTM5	7.23e-06	2	94	2	18692819
Pubmed	Impact of domain interchange on conformational stability and equilibrium folding of chimeric class micro glutathione transferases.	GSTM1 GSTM2	7.23e-06	2	94	2	12192076
Pubmed	GSTM1 and GSTM5 Genetic Polymorphisms and Expression in Age-Related Macular Degeneration.	GSTM1 GSTM5	7.23e-06	2	94	2	25897651
Pubmed	Glycosylation regulates NK cell-mediated effector function through PI3K pathway.	MGAT3 MGAT5	7.23e-06	2	94	2	20089585
Pubmed	Altered β1,6-GlcNAc and bisecting GlcNAc-branched N-glycan on integrin β1 are associated with early spontaneous miscarriage in humans.	MGAT3 MGAT5	7.23e-06	2	94	2	26109616
Pubmed	Defining the membrane proteome of NK cells.	MIA2 COPA PIK3C2A USP9X DHCR7 CDS2 DDX42 NUP188 LRBA HERPUD1 SLC37A4 FKBP5 NCDN	1.57e-05	1168	94	13	19946888
Pubmed	Glycoprotein glycosylation and cancer progression.	MGAT3 MGAT5	2.16e-05	3	94	2	10580127
Pubmed	The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin.	MGAT3 MGAT5	2.16e-05	3	94	2	19403558
Pubmed	Altered growth characteristics of skin fibroblasts from wild-derived mice, and genetic loci regulating fibroblast clone size.	GSTM2 GSTM4	2.16e-05	3	94	2	16842493
Pubmed	Purification and characterization of glutathione S-transferase of murine ovary and testis.	GSTM1 GSTM5	2.16e-05	3	94	2	8442656
Pubmed	Hereditary spastic paraplegias: identification of a novel SPG57 variant affecting TFG oligomerization and description of HSP subtypes in Sudan.	SACS ALS2	2.16e-05	3	94	2	27601211
Pubmed	The structure of two murine class-mu glutathione transferase genes coordinately induced by butylated hydroxyanisole.	GSTM1 GSTM4	2.16e-05	3	94	2	8512323
Pubmed	Genetic susceptibility, residential radon, and lung cancer in a radon prone area.	GSTM1 GSTM2	2.16e-05	3	94	2	24852519
Pubmed	Overexpression of N-acetylglucosaminyltransferases III and V in human melanoma cells. Implications for MCAM N-glycosylation.	MGAT3 MGAT5	2.16e-05	3	94	2	24726881
Pubmed	Biosynthesis of 14,15-hepoxilins in human l1236 Hodgkin lymphoma cells and eosinophils.	GSTM1 GSTM2	2.16e-05	3	94	2	21046276
Pubmed	Immunohistochemical and microarray analyses of a mouse model for the smith-lemli-opitz syndrome.	DHCR7 DCC	2.16e-05	3	94	2	16280635
Pubmed	A common variant in the glutathione S transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus.	GSTM1 GSTM2	2.16e-05	3	94	2	16002077
Pubmed	Glutathione-S-transferases and Chemotherapy Resistance of Hodgkin's Lymphoma Cell Lines.	GSTM1 GSTM4	2.16e-05	3	94	2	27466493
Pubmed	E-cadherin and adherens-junctions stability in gastric carcinoma: functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V.	MGAT3 MGAT5	2.16e-05	3	94	2	23671930
Pubmed	A basis for differentiating among the multiple human Mu-glutathione S-transferases and molecular cloning of brain GSTM5.	GSTM1 GSTM5	2.16e-05	3	94	2	8473333
Pubmed	An asparagine-phenylalanine substitution accounts for catalytic differences between hGSTM3-3 and other human class mu glutathione S-transferases.	GSTM4 GSTM5	2.16e-05	3	94	2	10587441
Pubmed	HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model.	MMS22L HERPUD1	4.32e-05	4	94	2	28423700
Pubmed	The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content.	CDS1 CDS2	4.32e-05	4	94	2	9407135
Pubmed	p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.	GSTM1 GSTM5	4.32e-05	4	94	2	17292829
Pubmed	Proteome-wide characterization of N-glycosylation events by diagonal chromatography.	CP SERPINA10 SERPINA6 SERPIND1	5.82e-05	77	94	4	16944957
Pubmed	Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain.	PIK3C2A ABCC9	7.19e-05	5	94	2	9514948
Pubmed	The consensus coding sequences of human breast and colorectal cancers.	MIA2 CD109	7.19e-05	5	94	2	16959974
Pubmed	Genetic polymorphisms in patients with endometriosis: an analytical study in Goiânia (Central West of Brazil).	GSTM1 ESR2	1.08e-04	6	94	2	27323100
Pubmed	A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.	CASD1 RIMS1	1.08e-04	6	94	2	19812333
Pubmed	CD73 Activity is Dispensable for the Polarization of M2 Macrophages.	MRC1 CHIA	1.08e-04	6	94	2	26258883
Pubmed	The absence of core fucose up-regulates GnT-III and Wnt target genes: a possible mechanism for an adaptive response in terms of glycan function.	MGAT3 MGAT5	1.08e-04	6	94	2	24619415
Pubmed	A review and comparison of the murine alpha1-antitrypsin and alpha1-antichymotrypsin multigene clusters with the human clade A serpins.	SERPINA10 SERPINA6	1.50e-04	7	94	2	12659817
Pubmed	Developmental changes in the cellular distribution of glutathione and glutathione S-transferases in the murine nervous system.	GSTM1 GSTM5	1.50e-04	7	94	2	8584275
Pubmed	Identification and characterization of CDS2, a mammalian homolog of the Drosophila CDP-diacylglycerol synthase gene.	CDS1 CDS2	1.50e-04	7	94	2	9889000
Pubmed	Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice.	GSTM1 CHIA	1.50e-04	7	94	2	16015370
Pubmed	Update of the human and mouse SERPIN gene superfamily.	SERPINA10 SERPINA6 SERPIND1	2.18e-04	43	94	3	24172014
Pubmed	Sox9-dependent expression of Gstm6 in Sertoli cells during testis development in mice.	GSTM1 GSTM5	2.57e-04	9	94	2	19098141
Pubmed	Complementary expression of transmembrane ephrins and their receptors in the mouse spinal cord: a possible role in constraining the orientation of longitudinally projecting axons.	EFNB1 DCC	2.57e-04	9	94	2	10704386
Pubmed	[Analysis of genetic predisposition to pulmonary tuberculosis in native Russians].	GSTM1 SLC11A1	2.57e-04	9	94	2	20297661
Pubmed	Genetic variants of glutathione S-transferase as possible risk factors for hepatocellular carcinoma: a HuGE systematic review and meta-analysis.	GSTM1 GSTM2	2.57e-04	9	94	2	18065725
Pubmed	Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina.	EFNB1 DCC	2.57e-04	9	94	2	10683176
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	LIPA COPA SACS USP9X EIF3B AHNAK2	2.91e-04	332	94	6	37433992
Pubmed	Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey.	GSTM1 GSTM4 GSTM5 CP	2.94e-04	117	94	4	18977241
Pubmed	A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.	GSTM1 GSTM4 GSTM5 CP	3.13e-04	119	94	4	17601350
Pubmed	Interstitial microRNA miR-214 attenuates inflammation and polycystic kidney disease progression.	MRC1 CHIA	3.21e-04	10	94	2	32182218
Pubmed	Neurodegeneration with Brain Iron Accumulation Disorders Overview	PANK2 CP	3.21e-04	10	94	2	23447832
Pubmed	Confirmation of genomewide association signals in Chinese Han population reveals risk loci for ischemic stroke.	MGAT5 ASTN2	3.91e-04	11	94	2	19910543
Pubmed	Tissue-specific expression and subcellular distribution of murine glutathione S-transferase class kappa.	GSTM1 GSTM5	3.91e-04	11	94	2	15100242
Pubmed	Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages.	MRC1 CHIA	3.91e-04	11	94	2	27732846
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	HAUS6 TTC28 SACS PIK3C2A FKBP5	4.12e-04	230	94	5	35449600
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	MMS22L COPA USP9X DHCR7 CDS2 EIF3B NUP188 NCDN	4.16e-04	657	94	8	36180527
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	EFNB1 COPA SACS LMO7 USP9X DHCR7 DDX42 EIF3B NUP188 NCDN	4.54e-04	1024	94	10	24711643
Pubmed	Multiple influences on the migration of precerebellar neurons in the caudal medulla.	EFNB1 DCC	4.69e-04	12	94	2	11807023
Pubmed	Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system.	RIMS1 DCC	4.69e-04	12	94	2	24009623
Pubmed	Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.	CP SERPINA10 SERPINA6	5.57e-04	59	94	3	17330941
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	HAUS6 SLC29A3 EFNB1 LMO7 USP9X NUP188 LRBA FITM2 SLC37A4 CEMIP2	5.97e-04	1061	94	10	33845483
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	CD109 CP SERPINA10 SERPINA6 SERPIND1	6.81e-04	257	94	5	16335952
Pubmed	Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.	GSTM1 GSTM4 ABCB11	7.73e-04	66	94	3	19898482
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	GSTM1 EFNB1 CDS2 ASTN2 DCC CEMIP2	8.26e-04	405	94	6	38187761
Pubmed	Incomplete deletion of IL-4Rα by LysM(Cre) reveals distinct subsets of M2 macrophages controlling inflammation and fibrosis in chronic schistosomiasis.	MRC1 CHIA	8.46e-04	16	94	2	25211233
Pubmed	A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS.	MRC1 ABCC9	9.57e-04	17	94	2	28634350
Pubmed	An investigation into the human serum "interactome".	MIA2 SACS CP DCC	9.99e-04	162	94	4	15174051
Pubmed	Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.	GSTM1 GSTM4 GSTM5	1.17e-03	76	94	3	19336475
Pubmed	Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.	COPA USP9X DDX42 MTBP	1.33e-03	175	94	4	37866880
Pubmed	Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage.	ESR2 SERPINA6	1.33e-03	20	94	2	20716560
Pubmed	Smad4 is required predominantly in the developmental processes dependent on the BMP branch of the TGF-β signaling system in the embryonic mouse retina.	DCC SMAD9	1.47e-03	21	94	2	21273545
Pubmed	Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.	SERPINA10 SERPINA6	1.47e-03	21	94	2	15014966
Pubmed	Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway.	DDX42 CD109	1.61e-03	22	94	2	32241891
Interaction	GSTM5 interactions	GSTM1 GSTM2 GSTM4 GSTM5	4.89e-07	15	90	4	int:GSTM5
Interaction	GSTM2 interactions	GSTM1 GSTM2 GSTM4 GSTM5	2.56e-06	22	90	4	int:GSTM2
Cytoband	1p13.3	GSTM1 GSTM2 GSTM4 GSTM5	1.29e-05	69	94	4	1p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	GSTM1 GSTM2 GSTM4 GSTM5 CHIA	7.70e-05	211	94	5	chr1p13
Cytoband	4q21.23	CDS1 COQ2	3.19e-04	13	94	2	4q21.23
Cytoband	9q21.32	SPATA31D4 SPATA31D3	6.93e-04	19	94	2	9q21.32
Cytoband	Ensembl 112 genes in cytogenetic band chr9q21	SPATA31D4 SPATA31D3 CEP78 CEMIP2	7.70e-04	199	94	4	chr9q21
GeneFamily	Glutathione S-transferases	GSTM1 GSTM2 GSTM4 GSTM5	2.31e-06	25	69	4	567
GeneFamily	Serpin peptidase inhibitors	SERPINA10 SERPINA6 SERPIND1	3.77e-04	37	69	3	739
GeneFamily	Mannosyl-glycoprotein N-acetylglucosaminyltransferases	MGAT3 MGAT5	5.08e-04	9	69	2	435
GeneFamily	PDZ domain containing	LMO7 RIMS1 PREX2 AHNAK2	2.72e-03	152	69	4	1220
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM4 ABCB11 CP SERPINA10 SERPIND1 SLC37A4	6.95e-08	168	94	7	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM4 ABCB11 CP SERPINA10 SERPIND1 SLC37A4	6.95e-08	168	94	7	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GSTM1 GSTM5 CDS1 PIK3C2A ABCB11 GRIN2C PREX2	2.28e-07	200	94	7	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	LPS-antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC35F3 CP DCC FITM2 RAB44 TSPAN1	6.25e-07	144	94	6	1b9e95e4f6e40042d3cf2f94c067f3a6b19428ea
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM4 ABCB11 SERPINA10 SERPINA6 SLC37A4	1.16e-06	160	94	6	c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM4 DHCR7 ABCB11 CP SERPIND1 SLC37A4	1.38e-06	165	94	6	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM4 ABCB11 CP SERPINA10 SLC37A4	1.59e-06	169	94	6	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM4 ABCB11 CP SERPINA10 SLC37A4	1.59e-06	169	94	6	7785cab967a33560830c394c918d6ce625103858
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM2 EFNB1 BEST3 CP ASTN2 SERPINA10	2.29e-06	180	94	6	6327c938a4f99df9fee714e44f15ea4a4a63ae15
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 TOMM7 MFSD14B COPA USP9X FKBP5	3.13e-06	190	94	6	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 CD1B EFNB1 SLC35F3 SPNS3 RUFY3	3.64e-06	195	94	6	4cbc36fb3ef9aef61367d3b37070a9a85fae1418
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD14B COPA ABCC9 CP FKBP5 RECK	3.75e-06	196	94	6	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD14B COPA ABCC9 CP FKBP5 RECK	3.75e-06	196	94	6	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	EFNB1 PIK3C2A CD109 RIMS1 FKBP5 CEMIP2	3.86e-06	197	94	6	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	Healthy_donor-cDC\|Healthy_donor / disease group, cell group and cell class (v2)	MRC1 CD1B CDS1 EFNB1 SPNS3 RUFY3	3.86e-06	197	94	6	b57a27e5b855bbdd1dfa352540599d260dc482aa
ToppCell	Healthy/Control-cDC\|World / Disease group and Cell class	MRC1 CD1B CDS1 EFNB1 SPNS3 RUFY3	3.86e-06	197	94	6	4497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCell	Healthy_donor-cDC\|World / disease group, cell group and cell class (v2)	MRC1 CD1B CDS1 EFNB1 SPNS3 RUFY3	3.86e-06	197	94	6	a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GSTM1 GSTM5 CDS1 ABCB11 GRIN2C PREX2	4.21e-06	200	94	6	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GSTM1 GSTM5 CDS1 ABCB11 GRIN2C PREX2	4.21e-06	200	94	6	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	Epithelial-Epithelial-D_(Clara-Club_cells)\|Epithelial / shred on cell class and cell subclass (v4)	GSTM1 GSTM2 CHIA BEST3 CP	6.36e-06	123	94	5	caa1576f1b5eb592d522be61c090ac444e277ac5
ToppCell	PND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 MGAT3 SLC35F3 CP TSPAN1	1.41e-05	145	94	5	9b69bfdbf91ef197b4c483617aa67498d9d2cd79
ToppCell	PND28-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 MGAT3 SLC35F3 CP TSPAN1	1.41e-05	145	94	5	31af9fce1dcd7e8ae1604476598e099232017ee9
ToppCell	PND28-Epithelial-Epithelial_Airway-Neurosecretory\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 MGAT3 SLC35F3 CP TSPAN1	1.41e-05	145	94	5	76f0cde9acdc3ad5948c007dccf312665972c9e6
ToppCell	droplet-Heart-nan-24m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAT3 CP CTNS KIAA2012 RUFY3	2.20e-05	159	94	5	7ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 CHIA MGAT3 CP TSPAN1	2.34e-05	161	94	5	c4970501c038ed36de447da70eabff020ad78713
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 CHIA MGAT3 CP TSPAN1	2.34e-05	161	94	5	41a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM2 CHIA MGAT3 CP TSPAN1	2.63e-05	165	94	5	6fdce8b23736409a23884ef3918638ffc067a86f
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM2 CHIA MGAT3 CP TSPAN1	2.63e-05	165	94	5	dd4d36ff8efb89fee1fb4c48d1b8f46902119909
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HAUS6 ZNF205 DCC PREX2 CEMIP2	2.63e-05	165	94	5	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	PND14-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM2 CHIA MGAT3 CP TSPAN1	2.63e-05	165	94	5	baff639a7046fb5cacb70f341b6d24cef3519f8e
ToppCell	COVID_vent-Lymphocytic-Dendritic-pDC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SLC35F3 SPNS3 HERPUD1 IFNLR1 AHNAK2	3.12e-05	171	94	5	779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCell	COVID_vent-Lymphocytic-Dendritic\|COVID_vent / Disease condition, Lineage, Cell class and subclass	SLC35F3 SPNS3 HERPUD1 IFNLR1 AHNAK2	3.12e-05	171	94	5	debbb071d260639b16269c94d172766908325c58
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 ALS2 UBLCP1 NCDN RUFY3	3.30e-05	173	94	5	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 ALS2 UBLCP1 NCDN RUFY3	3.30e-05	173	94	5	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM4 ABCB11 CP SERPIND1 SLC37A4	3.49e-05	175	94	5	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 CHIA MGAT3 CP TSPAN1	4.10e-05	181	94	5	092a971661b0aa06c1cdf428dbfa7339a26fb678
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM4 MGAT5 RAB44 SLC37A4	4.20e-05	182	94	5	8b16a13d8606d21a7a9ce1175237e9b4cf832ee0
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 GSTM2 CHIA MGAT3 TSPAN1	4.43e-05	184	94	5	49eccf72725593a8fb4a529e7985a5c413b3ca6a
ToppCell	PND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GSTM1 GSTM2 CHIA MGAT3 TSPAN1	4.43e-05	184	94	5	41164109d9d7bb1c431220e2e85e08dc5f56856d
ToppCell	facs-Brain_Myeloid-Cortex\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 SLC29A3 LRBA FKBP5 TSPAN1	4.43e-05	184	94	5	17f63dd671f9ff3dd2860d8de41b05c35c095950
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	MRC1 MGAT5 CCDC149 GRIN2C CEMIP2	4.54e-05	185	94	5	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 GSTM4 CCDC149 SPNS3 RAB44	4.54e-05	185	94	5	3f1aa91efae2d00320d126087cce1431ad5f26ea
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	EFNB1 CD109 RIMS1 PREX2 CEMIP2	4.54e-05	185	94	5	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	PIK3C2A CD109 PREX2 CEMIP2 SMAD9	4.91e-05	188	94	5	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 CD1B CDS1 SPNS3 RUFY3	5.03e-05	189	94	5	c81b38cda4525254fe4fa137a4c9bc9abe0363bb
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_5\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 CD1B CDS1 SPNS3 RUFY3	5.03e-05	189	94	5	807922b5ea0faddd3abfa9ec1b53f3f2b00e61bf
ToppCell	COVID-19-lung-Vein_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PIK3C2A CD109 PREX2 CEMIP2 SMAD9	5.16e-05	190	94	5	1caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	GSTM2 EFNB1 LMO7 ABCC9 CP	5.29e-05	191	94	5	78ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 CDS1 EFNB1 SPNS3 RUFY3	5.69e-05	194	94	5	b16ed97eb6b7b7a220e943474c0d85c141b6e3a5
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 CDS1 EFNB1 SPNS3 RUFY3	5.69e-05	194	94	5	2210f0755882d8f04edb4c109fb17c3f9149f6f7
ToppCell	Children_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EFNB1 CD109 RIMS1 PREX2 CEMIP2	5.69e-05	194	94	5	68004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell	COVID-19-kidney-Glomerular_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EFNB1 PIK3C2A CD109 PREX2 SMAD9	5.69e-05	194	94	5	660535b492445063d965095a50e1e299ce04c50a
ToppCell	(010)_cDC\|World / immune cells in Peripheral Blood (logTPM normalization)	MRC1 CD1B EFNB1 SPNS3 RUFY3	5.83e-05	195	94	5	4aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CDS1 CP RIMS1 KIAA2012 TSPAN1	5.83e-05	195	94	5	9651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MRC1 CD1B EFNB1 SPNS3 RUFY3	5.98e-05	196	94	5	e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCell	Control-Myeloid-cDC\|Control / Disease group, lineage and cell class	MRC1 CD1B EFNB1 SPNS3 RUFY3	5.98e-05	196	94	5	85d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 CD1B EFNB1 SPNS3 RUFY3	5.98e-05	196	94	5	553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MRC1 CD1B EFNB1 CD109 RUFY3	5.98e-05	196	94	5	0bac14c018487ca67e7f9255b5f186e7ae665774
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 CD1B EFNB1 SPNS3 RUFY3	5.98e-05	196	94	5	d376168e15ec1cf618723259966c76be3698b9b0
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MRC1 CD1B EFNB1 CD109 RUFY3	5.98e-05	196	94	5	33345338c825484960daa1ed82a19df38ccfc5c0
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	MRC1 CD1B EFNB1 SPNS3 RUFY3	5.98e-05	196	94	5	4a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-E\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	ABCC9 ABCA10 FKBP5 AHNAK2 SMAD9	6.12e-05	197	94	5	9b1c1d72c5a8c90d71ae31e4c198d2276872eaa0
ToppCell	mild_COVID-19-cDC\|World / disease group, cell group and cell class (v2)	MRC1 CD1B CDS1 SPNS3 RUFY3	6.12e-05	197	94	5	63e7b040c64f1e28b8db79980c7b580caa7d1b95
ToppCell	Healthy/Control-cDC\|Healthy/Control / Disease group and Cell class	MRC1 CDS1 EFNB1 SPNS3 RUFY3	6.12e-05	197	94	5	926423aae9fcf654f84b0f7621103a6a22d3aced
ToppCell	mild_COVID-19-cDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	MRC1 CD1B CDS1 SPNS3 RUFY3	6.12e-05	197	94	5	44ebd3f967779bb7753fc6dcd9fde6d682f9ccd6
ToppCell	BL-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDS1 LMO7 CP TSPAN1 AHNAK2	6.27e-05	198	94	5	6218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EFNB1 PIK3C2A CD109 PREX2 SMAD9	6.27e-05	198	94	5	1378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 CD1B EFNB1 SPNS3 RUFY3	6.27e-05	198	94	5	d0371e2ca9e25727b35985940f6228f9d8e49727
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EFNB1 PIK3C2A CD109 PREX2 SMAD9	6.27e-05	198	94	5	92416e65a0dc1a4bf931833407620ea05d362f56
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MRC1 CD1B EFNB1 SPNS3 RUFY3	6.27e-05	198	94	5	08ad0bece508bb4f9cc126d94839b5c89ce21ba8
ToppCell	AT2_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	CDS1 CHIA CASD1 DHCR7 ROS1	6.27e-05	198	94	5	893036558a9ad86b57f9e735df35812e9d18739e
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	EFNB1 STARD9 CD109 CP PREX2	6.27e-05	198	94	5	8689090bce9ab6e8f122426a404037e572c6713b
ToppCell	distal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ZDHHC2 MRC1 TOMM7 LIPA SLC11A1	6.27e-05	198	94	5	6aef5f5f89b508b214e1ab1876a743dedda0553b
ToppCell	facs-Tongue-nan-3m-Epithelial-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOMM7 MFSD14B COPA USP9X CD109	6.42e-05	199	94	5	8d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCell	COVID-19-kidney-Glomerular_EC\|kidney / Disease (COVID-19 only), tissue and cell type	MRC1 EFNB1 CD109 PREX2 SMAD9	6.42e-05	199	94	5	fffd2f9042b55531dac4e5b463b5cee80402e7bb
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CDS1 LMO7 CP ROS1 TSPAN1	6.58e-05	200	94	5	21d9cf3cd3696ad6b745c7c036798f04b6ce5160
ToppCell	Biopsy_Other_PF-Epithelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CDS1 LMO7 CP ROS1 TSPAN1	6.58e-05	200	94	5	1ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCell	Lung_Parenchyma-Severe-Epithelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CDS1 LMO7 CP ROS1 TSPAN1	6.58e-05	200	94	5	33658d5d09e2eaff60f4dd88837d4252328eab63
ToppCell	Parenchyma_COVID-19-Epithelial-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CDS1 LMO7 CP ROS1 TSPAN1	6.58e-05	200	94	5	d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCell	Parenchyma_Control_(B.)\|World / Sample group, Lineage and Cell type	MRC1 MGAT3 SLC11A1 MIA2 FKBP5	6.58e-05	200	94	5	220b6e5f936b3d08b031d6cabc5793213b98b8e2
ToppCell	Biopsy_Other_PF-Epithelial-SCGB3A2+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	LMO7 CP ROS1 RIMS1 TSPAN1	6.58e-05	200	94	5	631550dc34bcb605ab726645f4024d7828bb7975
ToppCell	Club_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CP RIMS1 NCDN TSPAN1	2.80e-04	149	94	4	81c813588bb5efb7b31141a75d387210dcb76094
ToppCell	TCGA-Lung\|World / Sample_Type by Project: Shred V9	MRC1 CHIA SLC11A1 ROS1	2.87e-04	150	94	4	8c133206786e8f22bb70f2a7de9c0cb7f9ea9313
ToppCell	Int-URO-Other\|Int-URO / Disease, Lineage and Cell Type	SLC35F3 LMO7 HERPUD1 TSPAN1	2.94e-04	151	94	4	ea5f25842e621be41a6491c9959d419d9cc7ebd6
ToppCell	Int-URO-Other-RBC\|Int-URO / Disease, Lineage and Cell Type	SLC35F3 LMO7 HERPUD1 TSPAN1	2.94e-04	151	94	4	0344d482f1c55c9eaa15beb8d6bac1c6cdca21b3
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GSTM1 GRIN2C KIAA2012 PREX2	3.09e-04	153	94	4	95b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GSTM1 GRIN2C KIAA2012 PREX2	3.09e-04	153	94	4	b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GSTM1 GRIN2C KIAA2012 PREX2	3.09e-04	153	94	4	3ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MRC1 CD1B LIPA SLC11A1	3.25e-04	155	94	4	03fd443740272dcb547e39deaf7ae89b8307f241
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MRC1 CDS1 PANK2 NCDN	3.33e-04	156	94	4	d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCB11 SERPINA10 SERPIND1 SLC37A4	3.33e-04	156	94	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZDHHC2 MMS22L CTNS FITM2	3.41e-04	157	94	4	bd45590da540a557dc8096980a45220fccb99505
ToppCell	frontal_cortex-Non-neuronal-astrocyte-Astro\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GSTM1 GRIN2C KIAA2012 PREX2	3.41e-04	157	94	4	0551442ae14685d8fe5729e3960c6324b1e05e4d
ToppCell	frontal_cortex-Non-neuronal-astrocyte\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GSTM1 GRIN2C KIAA2012 PREX2	3.41e-04	157	94	4	803af734d7f775d294391e2b84e472a732e18cef
ToppCell	frontal_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GSTM1 GRIN2C KIAA2012 PREX2	3.41e-04	157	94	4	9aa5304a9704da6dd4eda7d6940494b00e38b2e8
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZDHHC2 MMS22L CTNS FITM2	3.41e-04	157	94	4	00c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Club\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ESR2 CP RIMS1 TSPAN1	3.49e-04	158	94	4	03281e87780e3bacd089903383c016d03c373bf7
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GSTM1 ABCB11 CP SLC37A4	3.49e-04	158	94	4	9f58428f70d1427b20122c5c1cc7bf521d0f4832
ToppCell	metastatic_Brain-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	ROS1 SPNS3 IFNLR1 SMAD9	3.49e-04	158	94	4	ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LMO7 CP RIMS1 TSPAN1	3.58e-04	159	94	4	60b1f4dce2ce0911160fda17f137c064da31e2eb
Computational	ROS metabolism.	GSTM1 GSTM2 GSTM4 GSTM5	5.19e-06	22	58	4	MODULE_310
Computational	Genes in the cancer module 101.	GSTM2 GSTM4 GSTM5	1.74e-05	10	58	3	MODULE_101
Computational	Genes in the cancer module 132.	GSTM2 GSTM4 GSTM5	5.20e-05	14	58	3	MODULE_132
Drug	sulfobromophthalein	GSTM1 GSTM2 GSTM4 GSTM5 SLC6A7 ABCB11 SLC37A4	2.02e-07	103	92	7	CID000005345
Drug	Lyndiol	GSTM1 GSTM2 GSTM4 GSTM5 SERPINA6	2.45e-07	34	92	5	CID000082149
Drug	EUK-189	GSTM1 GSTM2 GSTM4 GSTM5	4.38e-07	16	92	4	ctd:C436526
Drug	Clch2cosg	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID000163913
Drug	C14791	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954044
Drug	C14793	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954046
Drug	C14803	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954054
Drug	C14805	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954056
Drug	C14804	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954055
Drug	C14806	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954057
Drug	C14848	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954067
Drug	C14856	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954069
Drug	C14855	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954068
Drug	S-(2,2-dichloro-1-hydroxy)ethylglutathione	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID011954070
Drug	AC1L4MYY	GSTM1 GSTM2 GSTM4 GSTM5	7.31e-07	18	92	4	CID000188517
Drug	2-(S-glutathionyl) acetyl glutathione	GSTM1 GSTM2 GSTM4 GSTM5	1.15e-06	20	92	4	CID011954072
Drug	C14865	GSTM1 GSTM2 GSTM4 GSTM5	1.15e-06	20	92	4	CID011954073
Drug	1-chloro-2,4-dinitrobenzene-glutathione conjugate	GSTM1 GSTM2 GSTM5	1.27e-06	6	92	3	ctd:C042630
Drug	S-(formylmethyl)glutathione	GSTM1 GSTM2 GSTM4 GSTM5	2.49e-06	24	92	4	CID011954074
Drug	AC1Q608X	GSTM1 GSTM2 GSTM4 GSTM5	4.75e-06	28	92	4	CID000128466
Drug	AC1L33DC	GSTM1 GSTM2 GSTM4 GSTM5	4.75e-06	28	92	4	CID000133757
Drug	BP-4,5-oxide	GSTM1 GSTM2 GSTM4 GSTM5 SLC6A7	4.80e-06	61	92	5	CID000037786
Drug	Phlorhizin	GSTM1 GSTM2 GSTM4 GSTM5 PIK3C2A USP9X HERPUD1 FKBP5	5.05e-06	235	92	8	ctd:D010695
Drug	2-BHA	GSTM1 GSTM2 GSTM4 GSTM5	5.49e-06	29	92	4	CID000006932
Drug	Dcvg	GSTM1 GSTM2 GSTM4 GSTM5	7.22e-06	31	92	4	CID006437359
Drug	o-dinitrobenzene	GSTM1 GSTM2 GSTM4 GSTM5	7.22e-06	31	92	4	CID000010707
Drug	zinc sulfate	GSTM1 GSTM2 GSTM4 GSTM5 CP	8.85e-06	69	92	5	CID000024424
Drug	4-propylphenol	GSTM1 GSTM2 ESR2	1.03e-05	11	92	3	ctd:C099327
Drug	glutathione reduced	GSTM1 GSTM2 GSTM4 GSTM5 SLC6A7 DAND5 PIK3C2A ABCB11 CP CTNS GRIN2C	1.03e-05	534	92	11	CID000000745
Drug	m-toluidine	GSTM1 GSTM2 GSTM4 GSTM5	1.06e-05	34	92	4	CID000007934
Drug	dimethoxystrychnine	GSTM1 GSTM2 GSTM4 GSTM5	1.19e-05	35	92	4	CID000009649
Drug	Dixan	GSTM1 GSTM2 GSTM4 GSTM5	1.19e-05	35	92	4	CID000010404
Drug	Glutathione	GSTM1 GSTM2 GSTM4 GSTM5	1.33e-05	36	92	4	DB00143
Drug	Glutathione S-(2,4 Dinitrobenzene)	GSTM1 GSTM2	1.62e-05	2	92	2	DB02458
Drug	cobaltocene	DAND5 CP	1.62e-05	2	92	2	CID000092884
Drug	Beta-sistosterol [83-46-5]; Up 200; 9.6uM; HL60; HT_HG-U133A	PIGQ CDS1 CDS2 CPA2 NUP188 RUFY3 CEMIP2	1.69e-05	200	92	7	2912_UP
Drug	Ethoxyquin	GSTM1 GSTM2 GSTM4 GSTM5	2.04e-05	40	92	4	ctd:D005015
Drug	4-hydroxyanisole	GSTM1 GSTM2 GSTM4 GSTM5	3.58e-05	46	92	4	CID000009015
Drug	oxidized glutathione	GSTM1 GSTM2 GSTM4 GSTM5 SLC6A7 DAND5 PIK3C2A	3.81e-05	227	92	7	CID000000975
Drug	C14802	GSTM1 GSTM2 GSTM4 GSTM5	3.90e-05	47	92	4	CID011954053
Drug	C14800	GSTM1 GSTM2 GSTM4 GSTM5	4.24e-05	48	92	4	CID011954051
Drug	felbamate	GSTM1 GSTM2 CP GRIN2C	4.24e-05	48	92	4	ctd:C047360
Drug	bromobenzene-3,4-oxide	GSTM1 GSTM2 GSTM4 GSTM5	4.60e-05	49	92	4	CID000108121
Drug	NSC-339901	PIK3C2A CP	4.83e-05	3	92	2	CID000433934
Drug	phenanthroline	GSTM1 GSTM2 GSTM4 GSTM5	4.99e-05	50	92	4	CID000067473
Drug	bromobenzene-2,3-oxide	GSTM1 GSTM2 GSTM4 GSTM5	4.99e-05	50	92	4	CID003036760
Drug	1,1-dichloroethylene epoxide	GSTM1 GSTM2 GSTM4 GSTM5	4.99e-05	50	92	4	CID000119521
Drug	naphthalene epoxide	GSTM1 GSTM2 GSTM4 GSTM5	5.39e-05	51	92	4	CID000108063
Drug	ethyl vinyl ether	MGAT3 MGAT5 HERPUD1	5.90e-05	19	92	3	CID000008023
Drug	dichloroacetaldehyde	GSTM1 GSTM2 GSTM4 GSTM5	6.76e-05	54	92	4	CID000006576
Drug	chloroacetyl chloride	GSTM1 GSTM2 GSTM4 GSTM5	7.27e-05	55	92	4	CID000006577
Drug	S-hexylglutathione	GSTM1 GSTM2 GSTM4 GSTM5	7.27e-05	55	92	4	CID000005140
Drug	oltipraz	GSTM1 GSTM2 GSTM4 ABCB11	7.81e-05	56	92	4	ctd:C026209
Drug	AC1L973H	LIPA CHIA COPA LRBA	8.37e-05	57	92	4	CID000439306
Drug	cyclohexanone	GSTM1 GSTM2 GSTM4 GSTM5	8.37e-05	57	92	4	CID000007967
Drug	tiadenol	GSTM1 GSTM2 GSTM4 GSTM5	8.37e-05	57	92	4	CID000023403
Drug	perhexiline	GSTM1 GSTM2 GSTM4 GSTM5	8.96e-05	58	92	4	CID000004746
Drug	bromoacetaldehyde	GSTM1 GSTM2 GSTM4 GSTM5	8.96e-05	58	92	4	CID000105131
Drug	diepoxybutane	GSTM1 GSTM2 GSTM4 GSTM5 EIF3B	9.61e-05	113	92	5	CID000011254
Drug	sulfolithocholic acid	GSTM1 GSTM2	9.64e-05	4	92	2	ctd:C014202
Drug	4-chloronitrobenzene	GSTM1 GSTM2	9.64e-05	4	92	2	ctd:C010407
Drug	Deladroxone	CP SERPINA6	9.64e-05	4	92	2	CID000032327
Drug	piriprost	GSTM1 GSTM2 GSTM4 GSTM5	1.02e-04	60	92	4	CID006437373
Drug	3,4,5,3',4'-pentachlorobiphenyl	GSTM1 ZDHHC2 GSTM2 GSTM5 MGAT3 EFNB1 UTP25 LMO7 ESR2 DHCR7 CP CPA2 SLC37A4 RUFY3 SMAD9	1.05e-04	1219	92	15	ctd:C023035
Drug	PenCB	GSTM1 GSTM2 GSTM4 GSTM5	1.09e-04	61	92	4	CID000036188
Drug	NSC39143	GSTM1 GSTM2 GSTM4 GSTM5	1.09e-04	61	92	4	CID000002579
Drug	Butylated Hydroxyanisole	GSTM1 GSTM2 GSTM4 GSTM5 ESR2	1.18e-04	118	92	5	ctd:D002083
Drug	DNCB	GSTM1 GSTM2 GSTM4 GSTM5 CD1B IFNLR1	1.19e-04	189	92	6	CID000000006
Drug	Hydralazine hydrochloride [304-20-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	COPA ASTN2 CTNS FKBP5 RUFY3 TSPAN1	1.30e-04	192	92	6	4746_DN
Drug	Trioxsalen [3902-71-4]; Up 200; 17.6uM; PC3; HT_HG-U133A	PIGQ GSTM5 SLC11A1 CTNS EZH1 PREX2	1.45e-04	196	92	6	5736_UP
Drug	AC1NSK22	GSTM1 GSTM2 GSTM4 GSTM5	1.49e-04	66	92	4	CID005311131
Drug	dicyclanil	GSTM1 GSTM2 GSTM5 ABCC9 SLC37A4	1.49e-04	124	92	5	ctd:C121718
Drug	Lisuride (S)(-) [18016-80-3]; Down 200; 11.8uM; PC3; HG-U133A	GSTM4 CDS1 SLC11A1 YIPF1 TTC28 CPA2	1.50e-04	197	92	6	1962_DN
Drug	Etofylline [519-37-9]; Up 200; 17.8uM; MCF7; HT_HG-U133A	ESR2 ASTN2 CTNS EZH1 SERPINA6 FKBP5	1.50e-04	197	92	6	5467_UP
Drug	2-butyl-6-methoxyphenol	GSTM1 GSTM2 GSTM4 GSTM5 SLC11A1 ESR2	1.50e-04	197	92	6	CID011954184
Drug	Doxepin hydrochloride [1229-29-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	YIPF1 ZNF205 ASTN2 CTNS NCDN TSPAN1	1.54e-04	198	92	6	7415_DN
Drug	pheophytin	GSTM1 GSTM2 GSTM4 GSTM5 PIK3C2A ABCB11 CP	1.55e-04	284	92	7	CID000000250
Drug	Oxybutynin chloride [1508-65-2]; Down 200; 10.2uM; PC3; HT_HG-U133A	CDS1 SLC29A3 TTC28 POLM CTNS NCDN	1.58e-04	199	92	6	7126_DN
Drug	rifapentine	ESR2 ABCB11	1.60e-04	5	92	2	ctd:C018421
Drug	2-S-glutathionylcaffeic acid	GSTM1 GSTM2	1.60e-04	5	92	2	ctd:C082398
Drug	hydrobenzoin	CDS1 LRBA	1.60e-04	5	92	2	CID000095447
Drug	Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT_HG-U133A	PIGQ GSTM5 ASTN2 CPA2 ABHD8 FKBP5	1.62e-04	200	92	6	5762_UP
Drug	ss,ss-carotene	GSTM1 GSTM2 GSTM4 GSTM5 CP ROS1	1.67e-04	201	92	6	CID000000573
Drug	BBCH	SLC6A7 CHIA SLC43A1	1.74e-04	27	92	3	CID000115288
Drug	benzyl isothiocyanate	GSTM1 GSTM2 GSTM4 GSTM5	1.97e-04	71	92	4	CID000002346
Drug	1,2-dibromoethane	GSTM1 GSTM2 GSTM4 GSTM5	1.97e-04	71	92	4	CID000007839
Drug	CAS 87-33-2	GSTM1 GSTM2 GSTM4 GSTM5	2.20e-04	73	92	4	CID000003780
Drug	NSC100058	MGAT3 MGAT5 ALS2 GRIN2C	2.31e-04	74	92	4	CID000003449
Drug	stilbene oxide	GSTM1 GSTM2 GSTM4 GSTM5	2.31e-04	74	92	4	CID000028649
Drug	oltipraz	GSTM1 GSTM2 GSTM4 GSTM5 ABCB11	2.37e-04	137	92	5	CID000047318
Drug	2-allylphenol	GSTM1 GSTM2	2.40e-04	6	92	2	ctd:C099328
Drug	hexylglutathione	GSTM1 GSTM2	2.40e-04	6	92	2	ctd:C033550
Drug	isomethyleugenol	GSTM1 GSTM2	2.40e-04	6	92	2	ctd:C031050
Drug	estradiol enanthate	CP SERPINA6	2.40e-04	6	92	2	CID000021070
Drug	CoCl2	GSTM1 GSTM2 GSTM4 GSTM5	2.44e-04	75	92	4	CID003015678
Drug	H088	ESR2 CP SERPINA6 TSPAN1	2.44e-04	75	92	4	CID000004542
Drug	2,4,6-trinitrotoluene	GSTM1 GSTM2 GSTM4 GSTM5	2.44e-04	75	92	4	CID000008376
Drug	AC1O5MYK	GSTM1 GSTM2 GSTM4 GSTM5	2.70e-04	77	92	4	CID006437077
Drug	NSC9567	GSTM1 GSTM2 GSTM4 GSTM5 SLC6A7	2.71e-04	141	92	5	CID000003001
Drug	BP-7,8-diol	GSTM1 GSTM2 GSTM4 GSTM5	2.83e-04	78	92	4	CID000025892
Disease	Brugada syndrome (implicated_via_orthology)	GSTM1 GSTM2 GSTM4 GSTM5	4.22e-10	5	91	4	DOID:0050451 (implicated_via_orthology)
Disease	Colorectal Carcinoma	GSTM1 ZDHHC2 ERCC6 SACS LMO7 ESR2 CD109 ABCB11 SPNS3 DCC ABCA10 PREX2 NCDN SMAD9	3.23e-08	702	91	14	C0009402
Disease	Degenerative Diseases, Central Nervous System	GSTM1 GSTM2 GSTM4 GSTM5 PANK2	1.32e-07	39	91	5	C0270715
Disease	Neurodegenerative Disorders	GSTM1 GSTM2 GSTM4 GSTM5 PANK2	1.32e-07	39	91	5	C0524851
Disease	Degenerative Diseases, Spinal Cord	GSTM1 GSTM2 GSTM4 GSTM5 PANK2	1.32e-07	39	91	5	C0751733
Disease	aspartate aminotransferase measurement	GSTM1 GSTM2 MRC1 LIPA PANK2 MGAT5 TTC28 ABCB11 ASTN2 LRBA SERPINA6 KIAA2012 HERPUD1	4.06e-06	904	91	13	EFO_0004736
Disease	level of glutathione S-transferase mu 1 in blood serum	GSTM1 GSTM2	9.41e-06	2	91	2	OBA_2041806
Disease	3,7-dimethylurate measurement	GSTM2 GSTM5	9.41e-06	2	91	2	EFO_0800949
Disease	Colorectal Neoplasms	GSTM1 ESR2 CD109 ABCB11 DCC ABCA10 SMAD9	2.46e-05	277	91	7	C0009404
Disease	HDL cholesterol change measurement	ESR2 ABCA10 HERPUD1	5.48e-05	24	91	3	EFO_0007805
Disease	glutathione S-transferase Mu 1 measurement	GSTM2 GSTM5	9.35e-05	5	91	2	EFO_0801638
Disease	larynx cancer (is_implicated_in)	GSTM1 ERCC6	1.40e-04	6	91	2	DOID:2596 (is_implicated_in)
Disease	HOMA-IR	SLC29A3 MGAT5 DCC	1.45e-04	33	91	3	EFO_0004501
Disease	apolipoprotein B measurement	GSTM1 GSTM2 GSTM5 DAND5 ABCB11 SERPINA10 SERPINA6 ABCA10 HERPUD1	2.10e-04	663	91	9	EFO_0004615
Disease	hypospadias (is_implicated_in)	GSTM1 ESR2	2.60e-04	8	91	2	DOID:10892 (is_implicated_in)
Disease	Thrombophilia	SERPINA10 SERPIND1	3.34e-04	9	91	2	C0398623
Disease	alpha-1-antitrypsin measurement	SERPINA10 SERPINA6	3.34e-04	9	91	2	EFO_0008327
Disease	cholestasis (implicated_via_orthology)	GSTM1 ABCB11	3.34e-04	9	91	2	DOID:13580 (implicated_via_orthology)
Disease	Diabetes, Autoimmune	SLC29A3 SLC11A1 CP	3.43e-04	44	91	3	C0205734
Disease	Brittle diabetes	SLC29A3 SLC11A1 CP	3.43e-04	44	91	3	C0342302
Disease	Diabetes Mellitus, Sudden-Onset	SLC29A3 SLC11A1 CP	3.43e-04	44	91	3	C4554117
Disease	Diabetes Mellitus, Ketosis-Prone	SLC29A3 SLC11A1 CP	3.43e-04	44	91	3	C3837958
Disease	Diabetes Mellitus, Insulin-Dependent	SLC29A3 SLC11A1 CP	3.67e-04	45	91	3	C0011854
Disease	apolipoprotein B to apolipoprotein A1 ratio	GSTM1 GSTM2 HERPUD1	4.72e-04	49	91	3	EFO_0021897
Disease	colorectal cancer (is_implicated_in)	GSTM1 ERCC6 ESR2 DCC	5.46e-04	121	91	4	DOID:9256 (is_implicated_in)
Disease	obesity (implicated_via_orthology)	GSTM1 GSTM2 GSTM4 GSTM5 ESR2	5.48e-04	215	91	5	DOID:9970 (implicated_via_orthology)
Disease	phospholipids in medium HDL measurement	GSTM1 GSTM2 HERPUD1	6.63e-04	55	91	3	EFO_0022295
Disease	free cholesterol to total lipids in large HDL percentage	GSTM1 GSTM2 HERPUD1	6.99e-04	56	91	3	EFO_0022279
Disease	esophageal cancer (is_implicated_in)	GSTM1 DCC	7.18e-04	13	91	2	DOID:5041 (is_implicated_in)
Disease	Neurodegeneration with brain iron accumulation	PANK2 CP	7.18e-04	13	91	2	cv:C2931845
Disease	low density lipoprotein particle size measurement	GSTM1 GSTM2 HERPUD1	7.74e-04	58	91	3	EFO_0008593
Disease	total lipids in medium HDL measurement	GSTM1 GSTM2 HERPUD1	7.74e-04	58	91	3	EFO_0022310
Disease	rheumatoid arthritis (is_implicated_in)	GSTM1 SLC11A1 ESR2	7.74e-04	58	91	3	DOID:7148 (is_implicated_in)
Disease	free cholesterol in medium HDL measurement	GSTM1 GSTM2 HERPUD1	7.74e-04	58	91	3	EFO_0022267
Disease	cholesterol in medium HDL measurement	GSTM1 GSTM2 HERPUD1	8.14e-04	59	91	3	EFO_0021903
Disease	phospholipids in HDL measurement	GSTM1 GSTM2 HERPUD1	8.97e-04	61	91	3	EFO_0022293
Disease	systemic lupus erythematosus (is_implicated_in)	GSTM1 SLC11A1 ESR2	9.41e-04	62	91	3	DOID:9074 (is_implicated_in)
Disease	dual specificity mitogen-activated protein kinase kinase 2 measurement	SERPINA10 SERPINA6	1.10e-03	16	91	2	EFO_0008112
Disease	ulcerative colitis (is_implicated_in)	GSTM1 SLC11A1	1.24e-03	17	91	2	DOID:8577 (is_implicated_in)
Disease	autism spectrum disorder (implicated_via_orthology)	GSTM1 GSTM5 RIMS1 LRBA	1.28e-03	152	91	4	DOID:0060041 (implicated_via_orthology)
Disease	Autistic Disorder	GSTM1 DHCR7 CP ASTN2 RIMS1	1.30e-03	261	91	5	C0004352
Disease	low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	GSTM1 GSTM2 ABCB11 HERPUD1	1.31e-03	153	91	4	EFO_0004611, EFO_0020946
Disease	glucose homeostasis measurement, acute insulin response measurement	ZDHHC2 ASTN2	1.39e-03	18	91	2	EFO_0006831, EFO_0006896
Disease	protein Z-dependent protease inhibitor measurement	SERPINA10 SERPINA6	1.39e-03	18	91	2	EFO_0021849
Disease	unipolar depression, bipolar disorder	STARD9 ESR2 ASTN2 DCC	1.41e-03	156	91	4	EFO_0003761, MONDO_0004985
Disease	inflammatory bowel disease (is_implicated_in)	GSTM1 SLC11A1	1.55e-03	19	91	2	DOID:0050589 (is_implicated_in)
Disease	Drug-Induced Liver Disease	GSTM1 GSTM2 GSTM4 CDS1 CP SERPINA6	1.59e-03	404	91	6	C0860207
Disease	Drug-Induced Acute Liver Injury	GSTM1 GSTM2 GSTM4 CDS1 CP SERPINA6	1.59e-03	404	91	6	C3658290
Disease	Hepatitis, Toxic	GSTM1 GSTM2 GSTM4 CDS1 CP SERPINA6	1.59e-03	404	91	6	C0019193
Disease	Chemically-Induced Liver Toxicity	GSTM1 GSTM2 GSTM4 CDS1 CP SERPINA6	1.59e-03	404	91	6	C4279912
Disease	Chemical and Drug Induced Liver Injury	GSTM1 GSTM2 GSTM4 CDS1 CP SERPINA6	1.59e-03	404	91	6	C4277682
Disease	Hepatitis, Drug-Induced	GSTM1 GSTM2 GSTM4 CDS1 CP SERPINA6	1.59e-03	404	91	6	C1262760
Disease	cortisol measurement	SERPINA10 SERPINA6	1.72e-03	20	91	2	EFO_0005843
Disease	saturated fatty acids to total fatty acids percentage	GSTM1 GSTM2	1.90e-03	21	91	2	EFO_0022305
Disease	cholangiocarcinoma (is_implicated_in)	GSTM1 PREX2	2.09e-03	22	91	2	DOID:4947 (is_implicated_in)
Disease	colorectal carcinoma (is_implicated_in)	GSTM1 ERCC6	2.09e-03	22	91	2	DOID:0080199 (is_implicated_in)
Disease	N-glycan measurement	MGAT3 MGAT5	2.09e-03	22	91	2	EFO_0004999
Disease	primary open angle glaucoma (is_implicated_in)	GSTM1 ESR2	2.28e-03	23	91	2	DOID:1070 (is_implicated_in)
Disease	Dystonia	PANK2 ERCC6 CP	2.41e-03	86	91	3	C0013421
Disease	systemic scleroderma (is_implicated_in)	GSTM1 SLC11A1	2.48e-03	24	91	2	DOID:418 (is_implicated_in)
Disease	bilirubin measurement	GSTM1 GSTM2 MFSD14B DDX42 ABCC9 ASTN2	2.49e-03	442	91	6	EFO_0004570
Disease	3-hydroxybutyrate measurement	SERPINA10 SERPINA6	2.69e-03	25	91	2	EFO_0010982
Disease	response to mTOR inhibitor	RIMS1 DCC	2.69e-03	25	91	2	EFO_0005417
Disease	response to interferon	ABCC9 RIMS1	2.69e-03	25	91	2	EFO_0007859
Disease	macular degeneration (is_marker_for)	GSTM1 ERCC6	2.91e-03	26	91	2	DOID:4448 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FLKRWSLPGFLGSSH	BEST3	586	Q8N1M1
SLKISGIKDFSWSPG	EIF3B	461	P55884
LSPKKTWEGFIGGFF	CDS1	271	Q92903
GDSPLFFLKSSFWSK	ABCA10	341	Q8WWZ4
GFLGVQRKFWPATLS	ALS2	1521	Q96Q42
PKKTWEGFIGGFFAT	CDS2	256	O95674
KTLLAIGGWNFGTAP	CHIA	91	Q9BZP6
STICGFLLGFFRGWK	ABCB11	226	O95342
LKFSTGGDKPAIWLD	CPA2	161	P48052
TFPILFIGWGSQSSK	ABCC9	41	O60706
VSIKSFFQPWLGDTG	CEP78	71	Q5JTW2
DSGTAIFLKPWSKGN	CD1B	61	P29016
KLFFNGRPGIVAWTL	DHCR7	236	Q9UBM7
WSLFDFIFPGKLGTL	ERCC6	686	Q03468
TFSLGQGLWLPVSKS	ASTN2	586	O75129
LSPCLAWSFLKAGFA	ABHD8	301	Q96I13
QFPFALLGWTGSKLF	POLM	426	Q9NP87
LWGLSGSLVAPAFKV	RAB44	481	Q7Z6P3
NSSLPGVFKKSDGWV	RECK	86	O95980
WLVFKTFFASLLPEG	HERPUD1	371	Q15011
FLIITSAWGGSKGPL	SERPIND1	11	P05546
LGIFLFLCSTPAWAK	CP	6	P00450
PFVFSLGKGQVIKAW	FKBP5	76	Q13451
FGENTKPWLSGFSVA	COQ2	271	Q96H96
LVPASALGSWKAFLG	DAND5	51	Q8N907
PNNLWYLFTGLEKGS	DCC	676	P43146
SWAKKIPGFVELSLF	ESR2	311	Q92731
WIPAGSSGSKFLALL	NCDN	296	Q9UBB6
AFWKEGAGNKTLFPV	IFNLR1	161	Q8IU57
FLGKRPWFAGDKITF	GSTM5	141	P46439
KSLYGFFWKQPGTLE	MGAT3	346	Q09327
PWKLSSQKLGFFLVT	MGAT5	6	Q09328
SSFSISWLPFKGLAN	MMS22L	436	Q6ZRQ5
KSPATFGLSGLWTLE	ASB18	101	Q6ZVZ8
KGEPFWVNLGLLLFS	SLC43A1	506	O75387
IAKTGSGKTAAFIWP	DDX42	296	Q86XP3
GVTGSFKDKPLAEWL	PIK3C2A	1201	O00443
FLGKQPWFLGDKITF	GSTM2	141	P28161
WSLFLPKTFSTRKGA	KIAA2012	56	Q0VF49
LFFSKLQGDKGRWPP	LRBA	171	P50851
KSLDFGFTIKWDIPG	LMO7	1051	Q8WWI1
GTFSLRKLWAFTGPG	SLC11A1	51	P49279
ILTKSGAWFFGSGPQ	RIMS1	171	Q86UR5
FPWFGLDIGGTLVKL	PANK2	211	Q9BZ23
SPKLWILVLGAVFGF	SLC37A4	326	O43826
KGDVTLTFLPLSFWG	CD109	261	Q6YHK3
QGAFEKIFSLWPLSK	CASD1	571	Q96PB1
SGLWSLPGGKDTILF	CCDC149	286	Q6ZUS6
LSQKVFGTLFGLLSW	FITM2	216	Q8N6M3
TNWPLLTVSKGFFEG	COPA	806	P53621
SWSSLNPKFLSGKGL	EFNB1	36	P98172
TIFLGFSGNFKPSWT	CEMIP2	1321	Q9UHN6
KTLNKLGVPFWLSSG	FKTN	286	O75072
KEFLGLSPFSLIKGW	HAUS6	381	Q7Z4H7
WTLIFGDPTKFGLGV	CTNS	326	O60931
LPFLTKPAGFSLDWK	SACS	2216	Q9NZJ4
IFFKGTWTQPFDLAS	SERPINA6	201	P08185
VWGRKPFLLGTVFFT	MFSD14C	106	Q5VZR4
VWGRKPFLLGTVFFT	MFSD14B	106	Q5SR56
LLVIWGEGKFPSAAS	MTBP	6	Q96DY7
LSLKPSWFDFGFAIL	MIA2	371	Q96PC5
GFSDLKALQGPLFWV	OR10P1	16	Q8NGE3
STSTIPKLLGIFWFG	OR52M1	76	Q8NGK5
KLFWLGLTYGSPSEG	MRC1	711	P22897
TFLGQNKSFWGPLEL	RUFY3	121	Q7L099
GIGSLLPWNFFITAK	SLC29A3	61	Q9BZD2
GSGSLWTTKFFIPLT	SLC29A3	336	Q9BZD2
SPKGWLVDLLNKFGT	USP9X	216	Q93008
LKWPILGQLFFSSKF	UTP25	216	Q68CQ4
FLGKRPWFVGDKITF	GSTM4	141	Q03013
FLGKRPWFAGNKITF	GSTM1	141	P09488
VFKLWPLSFLGSKLS	PIGQ	231	Q9BRB3
LAESFPFWASKGKLE	SPATA31D4	461	Q6ZUB0
FVKASASLKGQPWGL	STARD9	2226	Q9P2P6
FTKAAPFGVLWTLTN	SLC35F3	151	Q8IY50
SLGQFSSLGPLAVWK	SLC6A7	96	Q99884
LAVWKISPLFKGAGA	SLC6A7	106	Q99884
FSFTSPAVKRLLGWK	SMAD9	11	O15198
SKFQGPKLSTSGFEW	AHNAK2	4626	Q8IVF2
WFRFPKLGFSSSPTK	AHNAK2	5696	Q8IVF2
LAESFPFWASKGKLE	SPATA31D3	461	P0C874
LLAGQKKSSPFWTFE	YIPF1	66	Q9Y548
NAKPDWLKVGFTLGT	NDUFC1	36	O43677
AFVTGALGFWAPKFL	SPNS3	271	Q6ZMD2
LTAPGLSWKKFQGSF	STAG3L4	36	Q8TBR4
LLAPSDVAGWGTFIK	EZH1	616	Q92800
KPKFWENLTSPLFGT	NUP188	1006	Q5SRE5
FPKCFLGSEFVSWLL	PREX2	406	Q70Z35
LWSKPLNSFGPGEFL	ROS1	686	P08922
ILFKGKWLTPFDPVF	SERPINA10	236	Q9UK55
LYSWLLAPGAGIVKF	TTC28	1246	Q96AY4
KNGLSLGFPFSRPFW	ZNF205	156	O95201
PLGVIWGKFSEFYSK	UBLCP1	231	Q8WVY7
KKYWLLPIFSSLGDG	ZDHHC2	276	Q9UIJ5
FKGSQFAIRWGFIPL	TOMM7	16	Q9P0U1
WVSIDGASFLKIFGP	TSPAN1	31	O60635
KEFLPQSAFLKWLGT	LIPA	231	P38571
KSGGPAFTIGKSVWL	GRIN2C	591	Q14957