Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

AHNAK ELN FBN2

1.85e-0714173GO:0097493
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

ELN FBN2

4.48e-0512172GO:0030023
GeneOntologyMolecularFunctionextracellular matrix structural constituent

COL8A2 ELN FBN2

5.07e-04188173GO:0005201
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL8A2 ELN FBN2

2.18e-04114153MM14571
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

COL8A2 ELN FBN2

4.00e-04140153M587
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

ELN FBN2

5.15e-0432152MM14854
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

ELN FBN2

6.89e-0437152M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

ELN FBN2

7.65e-0439152MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

ELN FBN2

9.74e-0444152M26969
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL8A2 ELN FBN2

2.34e-03258153MM14572
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

COL8A2 ELN FBN2

3.59e-03300153M610
Pubmed

Assessment of fibrillin-2 and elastin gene polymorphisms in patients with a traumatic Achilles tendon rupture: Is Achilles tendon rupture a genetic disease?

ELN FBN2

2.53e-07218237140249
Pubmed

Interaction of tropoelastin with the amino-terminal domains of fibrillin-1 and fibrillin-2 suggests a role for the fibrillins in elastic fiber assembly.

ELN FBN2

7.59e-07318210825173
Pubmed

Characterization of Microfibrillar-associated Protein 4 (MFAP4) as a Tropoelastin- and Fibrillin-binding Protein Involved in Elastic Fiber Formation.

ELN FBN2

2.53e-06518226601954
Pubmed

Fibrillin-1 interactions with fibulins depend on the first hybrid domain and provide an adaptor function to tropoelastin.

ELN FBN2

2.53e-06518217255108
Pubmed

Caveolin1 Identifies a Specific Subpopulation of Cerebral Cortex Callosal Projection Neurons (CPN) Including Dual Projecting Cortical Callosal/Frontal Projection Neurons (CPN/FPN).

BHLHE22 BCL11B

2.53e-06518229379878
Pubmed

Genomic analysis of the Tapasin gene, located close to the TAP loci in the MHC.

RGL2 ZBTB22

5.30e-0671829521053
Pubmed

TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.

RGL2 ZBTB22

7.07e-0681829545376
Pubmed

Zac1 Regulates the Differentiation and Migration of Neocortical Neurons via Pac1.

BHLHE22 BCL11B

7.07e-06818226424889
Pubmed

Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly.

BHLHE22 BCL11B

9.09e-06918222284184
Pubmed

A network of genetic repression and derepression specifies projection fates in the developing neocortex.

BHLHE22 BCL11B

9.09e-06918223144223
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

ELN FBN2

9.09e-06918238844137
Pubmed

Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications.

BHLHE22 BCL11B

1.14e-051018226814051
Pubmed

A global genomic transcriptional code associated with CNS-expressed genes.

CPEB3 C19orf12 BHLHE22 BCL11B

1.90e-0531818416919269
Pubmed

FOXD1 is required for 3D patterning of the kidney interstitial matrix.

ELN FBN2

1.97e-051318236335435
Pubmed

Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons.

BHLHE22 BCL11B

3.42e-051718223749646
Pubmed

Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity.

BHLHE22 BCL11B

3.85e-051818235930666
Pubmed

Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons.

BHLHE22 BCL11B

3.85e-051818234161768
Pubmed

Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity.

BHLHE22 BCL11B

3.85e-051818227307230
Pubmed

Tle4 controls both developmental acquisition and early post-natal maturation of corticothalamic projection neuron identity.

BHLHE22 BCL11B

4.30e-051918237561632
Pubmed

Splicing factor TRA2B is required for neural progenitor survival.

BHLHE22 BCL11B

4.30e-051918223818142
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

COL8A2 ELN FBN2

4.47e-0513518328675934
Pubmed

HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development.

BHLHE22 BCL11B

5.28e-052118230709655
Pubmed

Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex.

BHLHE22 BCL11B

5.28e-052118228584103
Pubmed

Postmitotic regulation of sensory area patterning in the mammalian neocortex by Lhx2.

BHLHE22 BCL11B

5.81e-052218225971728
Pubmed

ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.

ELN FBN2

6.36e-052318226027930
Pubmed

Zbtb20 modulates the sequential generation of neuronal layers in developing cortex.

BHLHE22 BCL11B

7.54e-052518227282384
Pubmed

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.

DLGAP3 BCL11B

7.54e-052518228288114
Pubmed

Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex.

BHLHE22 BCL11B

8.16e-052618218957218
Pubmed

Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons.

BHLHE22 BCL11B

8.81e-052718222334647
Pubmed

High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.

RGL2 PRRC2A ZBTB22

9.67e-0517518319851445
Pubmed

Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex.

BHLHE22 BCL11B

1.02e-042918220615956
Pubmed

ADAMTS18 Deficiency Leads to Pulmonary Hypoplasia and Bronchial Microfibril Accumulation.

ELN FBN2

1.09e-043018232882513
Pubmed

Heritable Thoracic Aortic Disease Overview

ELN FBN2

1.09e-043018220301299
Pubmed

The QTL within the H2 Complex Involved in the Control of Tuberculosis Infection in Mice Is the Classical Class II H2-Ab1 Gene.

RGL2 ZBTB22

1.17e-043118226618355
Pubmed

Gene content of the 750-kb critical region for mouse embryonic ectoderm lethal tcl-w5.

RGL2 ZBTB22

1.58e-043618215112104
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

ELN FBN2

1.67e-043718234323105
Pubmed

Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala.

BHLHE22 BCL11B

1.76e-043818238086370
Pubmed

Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis.

ELN FBN2

1.95e-044018230578393
Pubmed

Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.

ELN FBN2

3.30e-045218230389913
Pubmed

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.

ELN FBN2

3.43e-045318233153107
Pubmed

Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.

BHLHE22 BCL11B

3.43e-045318227210758
Pubmed

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

PRRC2A AHNAK

3.56e-045418225631074
Pubmed

ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.

BCL11B ZBTB22

4.85e-046318234351428
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

BHLHE22 BCL11B

5.16e-046518226655900
Cytoband6p21.3

RGL2 PRRC2A ZBTB22

1.23e-042501836p21.3
CytobandEnsembl 112 genes in cytogenetic band chr6p21

RGL2 PRRC2A ZBTB22

9.44e-04503183chr6p21
CytobandEnsembl 112 genes in cytogenetic band chr1p34

COL8A2 DLGAP3

5.84e-03294182chr1p34
CoexpressionGSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN

RGL2 TMEM64 AHNAK BCL11B

9.08e-06199184M9443
CoexpressionFRANCO_BLOOD_SANOFI_PASTEUR_SA_INACTIVATED_INFLUENZA_VACCINE_CORRELATED_WITH_ANTIBODY_RESPONSE_AGE_18_40YO_0DY_POSITIVE

PAOX UBE2Z

1.02e-0422182M41051
CoexpressionSTAEGE_EWING_FAMILY_TUMOR

BHLHE22 BCL11B

2.18e-0432182M10582
CoexpressionGSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN

PAOX RGL2 AHNAK

2.53e-04183183M7627
CoexpressionGSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP

CPEB3 RGL2 BHLHE22

2.69e-04187183M7123
CoexpressionPLASARI_TGFB1_TARGETS_10HR_UP

COL8A2 TTC9 ELN

3.09e-04196183M2445
CoexpressionPLASARI_TGFB1_TARGETS_10HR_UP

COL8A2 TTC9 ELN

3.14e-04197183MM1320
CoexpressionGSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN

UBE2Z AHNAK PAN3

3.23e-04199183M7976
CoexpressionGSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP

C19orf12 BHLHE22 ZBTB22

3.28e-04200183M9030
CoexpressionGSE17721_POLYIC_VS_CPG_16H_BMDC_UP

RGL2 C19orf12 FBN2

3.28e-04200183M3950
CoexpressionGSE15330_LYMPHOID_MULTIPOTENT_VS_PRO_BCELL_DN

AHNAK C19orf12 ZBTB22

3.28e-04200183M7016
CoexpressionGSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

TMEM64 AHNAK C19orf12

3.28e-04200183M9166
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

COL8A2 ELN FBN2

3.28e-04200183M5930
CoexpressionGSE4748_CTRL_VS_LPS_STIM_DC_3H_UP

UBE2Z AHNAK BHLHE22

3.28e-04200183M6480
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 AHNAK BCL11B

2.48e-051431836e47dfc314909413e7642e3e5ac10c25857708c2
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

COL8A2 ELN FBN2

4.60e-05176183852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

COL8A2 ELN FBN2

4.60e-05176183d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM64 AHNAK BCL11B

4.92e-05180183d9dae9db8e17f6990032ee6cfa8393fae4768ca5
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

COL8A2 ELN FBN2

5.33e-051851837dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 ELN FBN2

5.33e-05185183785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 ELN FBN2

5.33e-0518518397a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 ELN FBN2

5.42e-0518618394d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

COL8A2 ELN FBN2

5.51e-051871835258674d0346e5c51a4b965efcdc1790c970845d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ELN BCL11B FBN2

5.51e-05187183d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

CPEB3 ACO2 FBN2

5.51e-0518718378cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

COL8A2 ELN PAN3

5.59e-0518818314bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellMatrixFB-Fibroblast-C|MatrixFB / shred on cell class and cell subclass (v4)

AHNAK ELN FBN2

5.77e-05190183d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 AHNAK BCL11B

5.86e-05191183ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellMesenchymal_cells-Arteriolar_fibro.|World / Lineage and Cell class

COL8A2 AHNAK ELN

6.14e-05194183c1e8923a50b4138a1e4c054c0c17b7f7122aa8a9
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL8A2 AHNAK ELN

6.33e-0519618324d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

AHNAK ELN FBN2

6.33e-05196183eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL8A2 AHNAK ELN

6.43e-051971836668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL8A2 AHNAK ELN

6.43e-051971837c275a2ac24a9a4f83fceda93a067e754837102f
ToppCellfacs-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACO2 AHNAK PAN3

6.52e-051981832f03f8897dd7cce6d8296638e14e11ec16bcf624
ToppCellfacs-Tongue-nan-3m|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACO2 AHNAK PAN3

6.52e-05198183f2a4057f038ef7225a5b98a7ab068c30dff4eadd
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 ELN FBN2

6.52e-05198183524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCellfacs-Tongue-nan-3m-Epithelial-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACO2 AHNAK PAN3

6.62e-051991838d50e1ee58710d896c0204937331d9f4dcd38de0
ToppCellwk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AHNAK ELN FBN2

6.62e-051991838de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial-Proteoglycan-expressing_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

AHNAK ELN FBN2

6.72e-0520018394ef227b2162ba77af33b8cc8aaa4a7e3bdf79a7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuroepithelial|3m / Sample Type, Dataset, Time_group, and Cell type.

AHNAK ELN FBN2

6.72e-05200183429028c3112d279b26abf3296e01b1884b4b7fcb
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|390C / Donor, Lineage, Cell class and subclass (all cells)

PAOX ZBTB22

8.99e-04111182dfbdeadad321392d359e6fb7112b28b043a4b874
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP3 TMEM64

1.19e-03128182e100629f6038e32176ffcc81bd06bd175df46cef
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DLGAP3 FBN2

1.23e-031301821720f16ac06951c3f57b6c3b0944670a571203d1
ToppCellfacs-Aorta-Heart-3m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2Z DLGAP3

1.27e-03132182dc13b54e38fbda9341972cef11833041f2f2a345
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BCL11B ZBTB22

1.29e-031331822ec3490cbf60152c3cece95eb566d749c9666517
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BHLHE22 BCL11B

1.34e-031361821f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-4|TCGA-Kidney / Sample_Type by Project: Shred V9

C19orf12 BHLHE22

1.36e-03137182758aa466a01265ed67b94f1578b4099956506271
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM64 BCL11B

1.42e-0314018294444b92acfad64d811ebb1545dc1dab64473795
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BHLHE22 BCL11B

1.42e-031401827cc891d676555609add6fc7880735d948a2ad801
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM64 BCL11B

1.42e-0314018211e441c3435ad8911ab401ca7d4ae1d3e5fa6eac
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Krt80|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BHLHE22 BCL11B

1.44e-0314118240ef6d792e11fe10963d64eb0b606b90556c1a70
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-2|TCGA-Thryoid / Sample_Type by Project: Shred V9

DLGAP3 BHLHE22

1.46e-03142182112f1b1bf7622e3bc1a2094c7710fab5a4083481
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tfh|Lung / Manually curated celltypes from each tissue

TTC9 BCL11B

1.46e-03142182319812c84fad93276bf093f2ad78db02ae745bf4
ToppCellfacs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BHLHE22

1.57e-031471829d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCellfacs-Marrow-B-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BHLHE22

1.57e-0314718238552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono|bone_marrow / Manually curated celltypes from each tissue

COL8A2 FBN2

1.59e-03148182de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DLGAP3 FBN2

1.59e-031481829205b26e0d042b342cc643cda0f4f3f8bb392d00
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

DLGAP3 BHLHE22

1.61e-031491826e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell(00)_Basal|World / shred by cell type and Timepoint

TMEM64 AHNAK

1.61e-0314918249e39206f37cee124ca4763c79425b805e50624b
ToppCellLeuk-UTI-Lymphocyte-T_NK-CD8_TCM|Leuk-UTI / Disease, Lineage and Cell Type

TTC9 BCL11B

1.63e-031501820a65f5e2f4e0b0e822b029e0222b28ba2db89e6d
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD8-Trm_gut_CD8|bone_marrow / Manually curated celltypes from each tissue

DLGAP3 TTC9

1.65e-031511825eebdc7ad6af3cc0263e4d8c3516818305ac38f2
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK ELN

1.67e-03152182d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCelldroplet-Liver-LIVER_HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK ELN

1.67e-03152182d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM64 FBN2

1.70e-03153182d6526d17826470534b766df144c74e73eb83fdad
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 BCL11B

1.70e-03153182cb144b8c487286384b47fdff88ff98fcf0508899
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK ZBTB22

1.72e-0315418289c9c9918af32f3952790b41f1471b2c80ffce2f
ToppCell368C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RGL2 BCL11B

1.72e-0315418266065c0763c83d98084ca6969694c3af37e43274
ToppCell368C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

RGL2 BCL11B

1.72e-03154182f29316d4b4dcdb23bd427d78068e65a9802f7f07
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|390C / Donor, Lineage, Cell class and subclass (all cells)

COL8A2 DLGAP3

1.74e-0315518215bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma|TCGA-Breast / Sample_Type by Project: Shred V9

RGL2 ELN

1.74e-03155182a4f2fffa8d0de760c556c3f8f1c91804eedbfa68
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AHNAK BCL11B

1.76e-03156182fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DLGAP3 ELN

1.81e-0315818284c0a215dabf697ada036c2b9592d0c61b5077de
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AHNAK BCL11B

1.83e-03159182bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BCL11B

1.83e-0315918294bc6ab248a8f02ccbc0facd24e0c7e9fda687d2
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PAOX BCL11B

1.83e-03159182b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAOX BCL11B

1.83e-03159182f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 AHNAK

1.83e-03159182d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCelldroplet-Liver-LIVER_NPC-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BCL11B

1.83e-03159182997963d879e5819683793cddf5e1acff1b81a1b8
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLGAP3 BCL11B

1.83e-0315918200a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCelldroplet-Liver-LIVER_NPC|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BCL11B

1.83e-03159182e4eaa88772835d6b78e1a18a0cec52de51e80339
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM64 BCL11B

1.83e-031591821dde4d19cc0fde7ebbccb4c31bb845a92206021b
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM64 BCL11B

1.83e-031591825c7a099aa84ecc62bf9b5e1609e5b6b77889f175
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 AHNAK

1.83e-03159182da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL8A2 FBN2

1.85e-03160182636127753e3a22831f39d4c8170df40901e4329d
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COL8A2 FBN2

1.85e-03160182cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCellPND01-03-samps|World / Age Group, Lineage, Cell class and subclass

ELN PAN3

1.88e-031611821973b112d8d67aacc02751797d0148e7b53bfa66
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AHNAK BCL11B

1.90e-0316218258da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BCL11B

1.90e-03162182b5b2cdbcc5bbfab52cc7d8a5504d34bb2e73771a
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PRRC2A BCL11B

1.90e-031621826ffcf369d954c20ce036aa1d072cee4e205f728e
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PRRC2A BCL11B

1.90e-03162182bcbf7f80a2a1c80def795e345f16cf16e8b9d03b
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AHNAK BCL11B

1.90e-031621824d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BCL11B

1.90e-031621824f9cf67b4b00b1cf78eeb9be1c701d535021a61d
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM64 BCL11B

1.92e-03163182476e94e1d132eaaecb9e376bd32748a75ad22081
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AHNAK ELN

1.94e-031641829eed945e9b0c1ee5fc62724ac2bbbed4267b0678
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell-SMC-SMC_Acta2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AHNAK ELN

1.94e-03164182f510f20e37e31b486cdd0e3f597ce4ff00877c5d
ToppCellfacs-Spleen-nan-3m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 AHNAK

1.94e-03164182a187bd5beca017ef657ef07c006e7f94ea3b911b
ToppCellprimary_visual_cortex-Non-neuronal-smooth_muscle_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AHNAK ELN

1.94e-031641825c932a462cbf81d029c8d11ec3aea3191529527b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK BCL11B

1.94e-031641828f3255d7f67890389a768453492243ea982eb38a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACO2 BCL11B

1.94e-03164182d8ecb3de6e34f5f574449e3d2f26fa0b2b7e84e8
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAOX BCL11B

1.94e-031641824e1861382c9e93856da19303474c8975c19706d2
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL8A2 ELN

1.94e-03164182a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCellfacs-Lung-EPCAM-24m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAOX BCL11B

1.94e-03164182467ad12884b70d243988174ae960ee2b7b6cfb0c
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

AHNAK TTC9

1.94e-0316418292fb94492fc2b683e9d50a9db6f01d23c194b0e4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BCL11B

1.97e-03165182eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCellfacs-Marrow-T-cells-3m-Lymphocytic-Klrb1a/b/c(-)_NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK BCL11B

1.97e-03165182651d40eadb1b34de618af94c167f43635729d43f
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 AHNAK

1.97e-031651828741df8066a44c841752a99ad306d26ea68f5344
ToppCell10x5'-Liver-Hematopoietic_progenitors|Liver / Manually curated celltypes from each tissue

COL8A2 FBN2

1.99e-03166182ae967570248cf86ca3ddf55e33bcbb3e4e3684bc
ToppCell10x5'-Liver-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Liver / Manually curated celltypes from each tissue

COL8A2 FBN2

1.99e-03166182a176e87aa6eec81d1fb79a028f759182d11b567d
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ELN FBN2

2.02e-0316718255c3c68af269fcf40f2b080ae4489523609ad388
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK BCL11B

2.02e-0316718283969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK ELN

2.02e-03167182e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM64 BCL11B

2.02e-031671825d1919bea8e5a52ac6fc953caff15509b7142923
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A2 AHNAK

2.02e-03167182aef22535a76e93472bcedacbb2c6991f3c9c8cd5
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM64 BCL11B

2.02e-03167182d8f497860d48342a3aaaad328f88e4d55ab4faeb
Drugisodesmosine

COL8A2 ELN FBN2

2.23e-0633183CID000013811
Drugdesmosine

COL8A2 ELN FBN2

9.48e-0653183CID000025435
DrugICI182,780; Down 200; 1uM; PC3; HT_HG-U133A

CPEB3 PAOX TTC9 ELN

1.45e-051951845969_DN
Diseaseinflammatory bowel disease

PRRC2A DLGAP3 ACO2 BCL11B

1.08e-04449174EFO_0003767
Diseasebreast carcinoma

CPEB3 DLGAP3 ACO2 C19orf12 FBN2

2.13e-041019175EFO_0000305
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

ELN FBN2

4.23e-0453172C4707243
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

PRRC2A ACO2 C19orf12

1.11e-03364173EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasecorneal topography

COL8A2 BCL11B

1.77e-03109172EFO_0004345
Diseasebody fat percentage

PRRC2A ACO2 C19orf12

2.57e-03488173EFO_0007800
Diseaseascending aortic diameter

ELN FBN2

2.90e-03140172EFO_0021787
Diseaseneurodegenerative disease (implicated_via_orthology)

ACO2 BCL11B

3.11e-03145172DOID:1289 (implicated_via_orthology)
Diseasegait measurement

C19orf12 ZBTB22

3.32e-03150172EFO_0007680

Protein segments in the cluster

PeptideGeneStartEntry
PNGGGLGGICIGVGG

ACO2

196

Q99798
VGGPPGLAVGGAVGG

C19orf12

56

Q9NSK7
GGGGGGGVGVPGLLV

BHLHE22

91

Q8NFJ8
IKGPTVGGGLPGIGV

AHNAK

5471

Q09666
VGGGLPGIGVQGLEG

AHNAK

5476

Q09666
PGVGGVPGGAAVGVK

PAN3

31

Q58A45
RENGGGGVPGVPGAG

BCL11B

566

Q9C0K0
AVGVGVGVGVGVPSP

CPEB3

271

Q8NE35
GVDGVGVPGAAGLPG

COL8A2

276

P25067
VGPEGGPAGAGVGGG

DLGAP3

71

O95886
VGGAGVGAGGQGPII

FBN2

471

P35556
AGVLPGVGGAGVPGV

ELN

271

P15502
GVGGAGVPGVPGAIP

ELN

276

P15502
GVPGVPGAIPGIGGI

ELN

281

P15502
PGAIPGIGGIAGVGT

ELN

286

P15502
GLVPGGPGFGPGVVG

ELN

321

P15502
GPGFGPGVVGVPGAG

ELN

326

P15502
PGVVGVPGAGVPGVG

ELN

331

P15502
VPGAGVPGVGVPGAG

ELN

336

P15502
RPGVGVGGIPTYGVG

ELN

386

P15502
GFGVGVGGIPGVAGV

ELN

406

P15502
VGGIPGVAGVPGVGG

ELN

411

P15502
GVAGVPGVGGVPGVG

ELN

416

P15502
PGVGGVPGVGGVPGV

ELN

421

P15502
VPGVPGTGGVPGVGT

ELN

471

P15502
VGVAPGVGVAPGVGV

ELN

506

P15502
GVGVAPGVGVAPGVG

ELN

511

P15502
GVAPGVGVAPGVGVA

ELN

531

P15502
VGVAPGVGVAPGIGP

ELN

536

P15502
GVGVAPGIGPGGVAA

ELN

541

P15502
GAGIPGLGVGVGVPG

ELN

576

P15502
GLGVGVGVPGLGVGA

ELN

581

P15502
VGVPGLGVGAGVPGL

ELN

586

P15502
LGVGAGVPGLGVGAG

ELN

591

P15502
GVPGLGVGAGVPGFG

ELN

596

P15502
VPGVLGGLGALGGVG

ELN

661

P15502
GGLGALGGVGIPGGV

ELN

666

P15502
LGGVGIPGGVVGAGP

ELN

671

P15502
GLGVGGLGVPGVGGL

ELN

711

P15502
GLGVPGVGGLGGIPP

ELN

716

P15502
PGGPRVLVVGGGIAG

PAOX

11

Q6QHF9
GGGPGGLVVGGGQEE

RGL2

31

O15211
VGTPGGGGGGAVPGI

PRRC2A

1351

P48634
GPGSGGGGVVVGVAE

TMEM64

91

Q6YI46
GVVGVSGSGGGFGPP

UBE2Z

26

Q9H832
VGSLGVPGSVGGVPG

ZBTB22

461

O15209
VPGGGGGAPARGQVG

TTC9

31

Q92623