Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	3-phosphoinositide-dependent protein kinase binding	PTK2B INSR	5.23e-05	3	84	2	GO:0043423
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH12 DNAH5 DNAH11	5.60e-05	18	84	3	GO:0008569
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SMG1 PTK2B TRPM7 PIM1 SHPK INSR DGKA FGFR3 POLQ ERN2 TAF1L PTK2 PARP15	1.41e-04	938	84	13	GO:0016772
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 PTK2B TRPM7 PIM1 SHPK INSR DGKA FGFR3 ERN2 TAF1L PTK2	1.84e-04	709	84	11	GO:0016773
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH12 DNAH5 DNAH11	2.18e-04	28	84	3	GO:0051959
GeneOntologyMolecularFunction	kinase activity	SMG1 PTK2B TRPM7 PIM1 SHPK INSR DGKA FGFR3 ERN2 TAF1L PTK2	3.49e-04	764	84	11	GO:0016301
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH12 DNAH5 DNAH11	5.03e-04	37	84	3	GO:0045505
GeneOntologyMolecularFunction	protein kinase activity	SMG1 PTK2B TRPM7 PIM1 INSR FGFR3 ERN2 TAF1L PTK2	9.33e-04	600	84	9	GO:0004672
GeneOntologyBiologicalProcess	positive regulation of protein phosphorylation	PTPN5 PTK2B THBS4 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 ERN2 PTK2	5.28e-06	724	82	13	GO:0001934
GeneOntologyBiologicalProcess	positive regulation of phosphorylation	PTPN5 PTK2B THBS4 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 ERN2 PTK2	1.17e-05	780	82	13	GO:0042327
GeneOntologyBiologicalProcess	positive regulation of protein modification process	PTPN5 PTK2B THBS4 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 RWDD3 ERN2 PTK2	1.78e-05	937	82	14	GO:0031401
GeneOntologyBiologicalProcess	positive regulation of kinase activity	PTK2B EGF COPS8 PIM1 INSR ETAA1 FGFR3 ERN2 PTK2	3.28e-05	405	82	9	GO:0033674
GeneOntologyBiologicalProcess	protein autophosphorylation	SMG1 PTK2B TRPM7 PIM1 INSR TNKS1BP1 PTK2	3.46e-05	228	82	7	GO:0046777
GeneOntologyBiologicalProcess	positive regulation of phosphate metabolic process	PTPN5 PTK2B THBS4 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 ERN2 PTK2	4.09e-05	879	82	13	GO:0045937
GeneOntologyBiologicalProcess	positive regulation of phosphorus metabolic process	PTPN5 PTK2B THBS4 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 ERN2 PTK2	4.09e-05	879	82	13	GO:0010562
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	PTK2B EGF PLEKHG4 ARHGEF10 COPS8 PIM1 INSR ETAA1 CLDN4 FGFR3 CCL21 ERN2 ADCY3 PTK2	4.93e-05	1028	82	14	GO:0043085
GeneOntologyBiologicalProcess	positive regulation of protein metabolic process	PTPN5 PTK2B THBS4 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 PIWIL2 CLDN4 FGFR3 CCL21 RWDD3 ERN2 PTK2	4.96e-05	1458	82	17	GO:0051247
GeneOntologyBiologicalProcess	receptor-mediated endocytosis	PTPN5 ARR3 CLTCL1 EGF IGHE ACKR3 INSR CCL21	5.83e-05	337	82	8	GO:0006898
GeneOntologyBiologicalProcess	positive regulation of protein kinase activity	PTK2B EGF COPS8 PIM1 INSR ETAA1 ERN2 PTK2	7.59e-05	350	82	8	GO:0045860
GeneOntologyBiologicalProcess	peptidyl-tyrosine autophosphorylation	PTK2B INSR PTK2	8.83e-05	22	82	3	GO:0038083
GeneOntologyBiologicalProcess	regulation of protein phosphorylation	PTPN5 PTK2B THBS4 ARR3 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 ERN2 PTK2	1.39e-04	1133	82	14	GO:0001932
GeneOntologyBiologicalProcess	positive regulation of transferase activity	PTK2B EGF COPS8 PIM1 INSR ETAA1 FGFR3 ERN2 PTK2	1.41e-04	490	82	9	GO:0051347
GeneOntologyBiologicalProcess	positive regulation of receptor-mediated endocytosis	PTPN5 EGF INSR CCL21	1.47e-04	67	82	4	GO:0048260
GeneOntologyBiologicalProcess	cilium movement involved in cell motility	DNAH12 SPEF2 DNAH5 ADCY3 CFAP157 DNAH11	1.91e-04	210	82	6	GO:0060294
GeneOntologyBiologicalProcess	cilium-dependent cell motility	DNAH12 SPEF2 DNAH5 ADCY3 CFAP157 DNAH11	2.17e-04	215	82	6	GO:0060285
GeneOntologyBiologicalProcess	cilium or flagellum-dependent cell motility	DNAH12 SPEF2 DNAH5 ADCY3 CFAP157 DNAH11	2.17e-04	215	82	6	GO:0001539
GeneOntologyBiologicalProcess	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	PTK2B EGF INSR FGFR3 CCL21 PTK2	2.28e-04	217	82	6	GO:0051897
GeneOntologyBiologicalProcess	regulation of phosphorylation	PTPN5 PTK2B THBS4 ARR3 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 ERN2 PTK2	3.14e-04	1226	82	14	GO:0042325
GeneOntologyBiologicalProcess	peptidyl-tyrosine phosphorylation	PTK2B THBS4 EGF PTPRZ1 INSR FGFR3 PTK2	3.24e-04	327	82	7	GO:0018108
GeneOntologyBiologicalProcess	positive regulation of receptor internalization	PTPN5 EGF INSR	3.32e-04	34	82	3	GO:0002092
GeneOntologyBiologicalProcess	peptidyl-tyrosine modification	PTK2B THBS4 EGF PTPRZ1 INSR FGFR3 PTK2	3.37e-04	329	82	7	GO:0018212
GeneOntologyBiologicalProcess	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	PTK2B EGF INSR CNTNAP2 FGFR3 CCL21 PTK2	3.68e-04	334	82	7	GO:0051896
GeneOntologyBiologicalProcess	regulation of macrophage chemotaxis	PTK2B CCL21 PTK2	4.27e-04	37	82	3	GO:0010758
GeneOntologyBiologicalProcess	protein localization to motile cilium	EFCAB7 DNAH11	4.30e-04	8	82	2	GO:0120229
GeneOntologyBiologicalProcess	signal complex assembly	PTK2B PTK2	4.30e-04	8	82	2	GO:0007172
GeneOntologyBiologicalProcess	positive regulation of molecular function	PTK2B EGF PLEKHG4 ARHGEF10 COPS8 PIM1 INSR ETAA1 NCBP1 CLDN4 FGFR3 CCL21 ERN2 ADCY3 PTK2	4.62e-04	1430	82	15	GO:0044093
GeneOntologyBiologicalProcess	cilium movement	DNAH12 SPEF2 DNAH5 ADCY3 CFAP157 DNAH11	6.08e-04	261	82	6	GO:0003341
GeneOntologyBiologicalProcess	regulation of protein modification process	PTPN5 PTK2B THBS4 ARR3 EGF COPS8 PTPRZ1 PIM1 INSR ETAA1 TNKS1BP1 FGFR3 RWDD3 ERN2 PTK2	7.00e-04	1488	82	15	GO:0031399
GeneOntologyBiologicalProcess	learning or memory	TRPM7 PTPRZ1 INSR CNTNAP2 CHRD ADCY3 DNAH11	7.10e-04	373	82	7	GO:0007611
GeneOntologyBiologicalProcess	cell-matrix adhesion	PTK2B THBS3 TRPM7 CCL21 PARVG PTK2	7.25e-04	270	82	6	GO:0007160
GeneOntologyCellularComponent	cilium	DLG5 ARR3 DNAH12 GLE1 SPEF2 PRAMEF13 EFCAB7 DNAH5 ADCY3 PTK2 CFAP157 DNAH11	1.91e-04	898	82	12	GO:0005929
GeneOntologyCellularComponent	9+0 motile cilium	DNAH5 DNAH11	2.26e-04	6	82	2	GO:0097728
MousePheno	biventricular, ambiguous atrioventricular connection	DNAH5 DNAH11	2.13e-05	2	65	2	MP:0011511
MousePheno	prognathia	SMG1 FGFR3	6.37e-05	3	65	2	MP:0010208
MousePheno	biventricular, discordant atrioventricular connection	DNAH5 DNAH11	6.37e-05	3	65	2	MP:0011510
Domain	Focal_AT	PTK2B PTK2	1.95e-05	2	83	2	PF03623
Domain	Focal_adhesion_kin_target_dom	PTK2B PTK2	1.95e-05	2	83	2	IPR005189
Domain	Focal_adhesion_target_reg	PTK2B PTK2	1.95e-05	2	83	2	PD006413
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH5 DNAH11	2.97e-05	14	83	3	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH5 DNAH11	2.97e-05	14	83	3	IPR013602
Domain	DHC_N2	DNAH12 DNAH5 DNAH11	2.97e-05	14	83	3	PF08393
Domain	AAA_8	DNAH12 DNAH5 DNAH11	2.97e-05	14	83	3	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH5 DNAH11	2.97e-05	14	83	3	IPR011704
Domain	AAA_5	DNAH12 DNAH5 DNAH11	2.97e-05	14	83	3	PF07728
Domain	DHC_fam	DNAH12 DNAH5 DNAH11	3.70e-05	15	83	3	IPR026983
Domain	Dynein_heavy_dom	DNAH12 DNAH5 DNAH11	3.70e-05	15	83	3	IPR004273
Domain	Dynein_heavy	DNAH12 DNAH5 DNAH11	3.70e-05	15	83	3	PF03028
Domain	Thbs/COMP_coiled-coil	THBS3 THBS4	5.84e-05	3	83	2	IPR024665
Domain	COMP	THBS3 THBS4	5.84e-05	3	83	2	PF11598
Domain	TSP_3	THBS3 THBS4	1.93e-04	5	83	2	PF02412
Domain	TSP3	THBS3 THBS4	1.93e-04	5	83	2	PS51234
Domain	TSP_CTER	THBS3 THBS4	1.93e-04	5	83	2	PS51236
Domain	-	THBS3 THBS4	1.93e-04	5	83	2	4.10.1080.10
Domain	Thrombospondin_C	THBS3 THBS4	1.93e-04	5	83	2	IPR008859
Domain	TSP_C	THBS3 THBS4	1.93e-04	5	83	2	PF05735
Domain	Thrombospondin_3_rpt	THBS3 THBS4	1.93e-04	5	83	2	IPR017897
Domain	Thrombospondin_3-like_rpt	THBS3 THBS4	1.93e-04	5	83	2	IPR003367
Domain	TSP_type-3_rpt	THBS3 THBS4	1.93e-04	5	83	2	IPR028974
Domain	DHC_N1	DNAH5 DNAH11	5.37e-04	8	83	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH5 DNAH11	5.37e-04	8	83	2	IPR013594
Domain	TyrKc	PTK2B INSR FGFR3 PTK2	6.37e-04	88	83	4	SM00219
Domain	Tyr_kinase_cat_dom	PTK2B INSR FGFR3 PTK2	6.37e-04	88	83	4	IPR020635
Domain	PROTEIN_KINASE_TYR	PTK2B INSR FGFR3 PTK2	9.18e-04	97	83	4	PS00109
Domain	Tyr_kinase_AS	PTK2B INSR FGFR3 PTK2	9.18e-04	97	83	4	IPR008266
Domain	-	DLG5 DNAH12 ABCA6 ERCC6L SPEF2 BTAF1 POLQ DNAH5 GPN3 DNAH11	1.70e-03	746	83	10	3.40.50.300
Domain	Dynein_HC_stalk	DNAH5 DNAH11	1.72e-03	14	83	2	IPR024743
Domain	MT	DNAH5 DNAH11	1.72e-03	14	83	2	PF12777
Domain	uDENN	SBF2 DENND3	1.97e-03	15	83	2	PF03456
Domain	Laminin_G	THBS3 THBS4 CNTNAP2	2.19e-03	58	83	3	IPR001791
Domain	UDENN	SBF2 DENND3	2.25e-03	16	83	2	PS50946
Domain	DDENN	SBF2 DENND3	2.25e-03	16	83	2	PS50947
Domain	DENN	SBF2 DENND3	2.25e-03	16	83	2	SM00799
Domain	dDENN	SBF2 DENND3	2.25e-03	16	83	2	SM00801
Domain	DENN	SBF2 DENND3	2.25e-03	16	83	2	PF02141
Domain	dDENN_dom	SBF2 DENND3	2.25e-03	16	83	2	IPR005112
Domain	uDENN_dom	SBF2 DENND3	2.25e-03	16	83	2	IPR005113
Domain	dDENN	SBF2 DENND3	2.25e-03	16	83	2	PF03455
Domain	DENN	SBF2 DENND3	2.25e-03	16	83	2	PS50211
Domain	DENN_dom	SBF2 DENND3	2.25e-03	16	83	2	IPR001194
Domain	Pkinase_Tyr	PTK2B INSR FGFR3 PTK2	2.62e-03	129	83	4	PF07714
Domain	Kinase-like_dom	SMG1 PTK2B TRPM7 PIM1 INSR FGFR3 ERN2 PTK2	2.80e-03	542	83	8	IPR011009
Domain	Ser-Thr/Tyr_kinase_cat_dom	PTK2B INSR FGFR3 PTK2	3.34e-03	138	83	4	IPR001245
Domain	HEAT_REPEAT	SMG1 IPO13 BTAF1	3.74e-03	70	83	3	PS50077
Domain	TPR-like_helical_dom	CLTCL1 ERCC6L TTC3 CDC27 TTC38	3.82e-03	233	83	5	IPR011990
Domain	AAA+_ATPase	DNAH12 ABCA6 DNAH5 DNAH11	3.89e-03	144	83	4	IPR003593
Domain	AAA	DNAH12 ABCA6 DNAH5 DNAH11	3.89e-03	144	83	4	SM00382
Domain	ARM-type_fold	USP34 SMG1 CLTCL1 IPO13 NCBP1 BTAF1	4.00e-03	339	83	6	IPR016024
Domain	P-loop_NTPase	DLG5 DNAH12 ABCA6 ERCC6L SPEF2 BTAF1 POLQ DNAH5 GPN3 DNAH11	4.28e-03	848	83	10	IPR027417
Pubmed	Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases.	PTK2B INSR PTK2	1.45e-07	5	86	3	7529876
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH12 DNAH5 DNAH11	5.07e-07	7	86	3	9256245
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH12 DNAH5 DNAH11	5.21e-06	14	86	3	9373155
Pubmed	Differential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell lines.	PTK2B PTK2	6.04e-06	2	86	2	21533871
Pubmed	Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity.	PTK2B PTK2	6.04e-06	2	86	2	21471206
Pubmed	Decreased cell adhesion promotes angiogenesis in a Pyk2-dependent manner.	PTK2B PTK2	6.04e-06	2	86	2	21640103
Pubmed	Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation.	PTK2B PTK2	6.04e-06	2	86	2	15096502
Pubmed	PTK2b function during fertilization of the mouse oocyte.	PTK2B PTK2	6.04e-06	2	86	2	24667605
Pubmed	The FERM domain: organizing the structure and function of FAK.	PTK2B PTK2	6.04e-06	2	86	2	20966971
Pubmed	Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.	PTK2B PTK2	6.04e-06	2	86	2	18391070
Pubmed	Different modes and qualities of tyrosine phosphorylation of Fak and Pyk2 during epithelial-mesenchymal transdifferentiation and cell migration: analysis of specific phosphorylation events using site-directed antibodies.	PTK2B PTK2	6.04e-06	2	86	2	11420674
Pubmed	Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells.	PTK2B PTK2	6.04e-06	2	86	2	29133485
Pubmed	Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair.	PTK2B PTK2	6.04e-06	2	86	2	30872746
Pubmed	Enteric glia promote intestinal mucosal healing via activation of focal adhesion kinase and release of proEGF.	EGF PTK2	6.04e-06	2	86	2	21350188
Pubmed	Mutation screening of ACKR3 and COPS8 in kidney cancer cases from the CONFIRM study.	COPS8 ACKR3	6.04e-06	2	86	2	28063109
Pubmed	Non-overlapping functions for Pyk2 and FAK in osteoblasts during fluid shear stress-induced mechanotransduction.	PTK2B PTK2	6.04e-06	2	86	2	21283581
Pubmed	Spatial and Temporal Regulation of Receptor Tyrosine Kinase Activation and Intracellular Signal Transduction.	EGF INSR	6.04e-06	2	86	2	27023845
Pubmed	Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.	DNAH5 DNAH11	6.04e-06	2	86	2	32357925
Pubmed	Cultured human retinal pigment epithelial cells differentially express thrombospondin-1, -2, -3, and -4.	THBS3 THBS4	6.04e-06	2	86	2	11137453
Pubmed	Ciliary defects and genetics of primary ciliary dyskinesia.	DNAH5 DNAH11	6.04e-06	2	86	2	19410201
Pubmed	Safety, pharmacokinetic, and pharmacodynamic phase I dose-escalation trial of PF-00562271, an inhibitor of focal adhesion kinase, in advanced solid tumors.	PTK2B PTK2	6.04e-06	2	86	2	22454420
Pubmed	Proline-rich tyrosine kinase 2 and focal adhesion kinase are involved in different phases of platelet activation by vWF.	PTK2B PTK2	6.04e-06	2	86	2	11916084
Pubmed	Pyk2 Stabilizes Striatal Medium Spiny Neuron Structure and Striatal-Dependent Action.	PTK2B PTK2	6.04e-06	2	86	2	34943950
Pubmed	Striatal-enriched protein-tyrosine phosphatase (STEP) regulates Pyk2 kinase activity.	PTPN5 PTK2B	6.04e-06	2	86	2	22544749
Pubmed	Protein tyrosine kinase signaling in the mouse oocyte cortex during sperm-egg interactions and anaphase resumption.	PTK2B PTK2	6.04e-06	2	86	2	23401167
Pubmed	B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.	PTK2B PTK2	6.04e-06	2	86	2	19561089
Pubmed	Lineage-specific biology revealed by a finished genome assembly of the mouse.	DNAH12 CCL21 CDC27 FER1L5	1.08e-05	55	86	4	19468303
Pubmed	CRISPR/Cas9 engineering of ERK5 identifies its FAK/PYK2 dependent role in adhesion-mediated cell survival.	PTK2B PTK2	1.81e-05	3	86	2	30952431
Pubmed	Targeted inhibition of FAK, PYK2 and BCL-XL synergistically enhances apoptosis in ovarian clear cell carcinoma cell lines.	PTK2B PTK2	1.81e-05	3	86	2	24523919
Pubmed	Role of focal adhesion tyrosine kinases in GPVI-dependent platelet activation and reactive oxygen species formation.	PTK2B PTK2	1.81e-05	3	86	2	25415317
Pubmed	Suppression of Pyk2 kinase and cellular activities by FIP200.	PTK2B PTK2	1.81e-05	3	86	2	10769033
Pubmed	Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.	THBS3 THBS4	1.81e-05	3	86	2	33910854
Pubmed	FAK and Pyk2 activity promote TNF-α and IL-1β-mediated pro-inflammatory gene expression and vascular inflammation.	PTK2B PTK2	1.81e-05	3	86	2	31110200
Pubmed	Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis.	PTK2B PTK2	1.81e-05	3	86	2	17581824
Pubmed	Focal adhesion kinase-related proline-rich tyrosine kinase 2 and focal adhesion kinase are co-overexpressed in early-stage and invasive ErbB-2-positive breast cancer and cooperate for breast cancer cell tumorigenesis and invasiveness.	PTK2B PTK2	1.81e-05	3	86	2	18832579
Pubmed	Regulation of osteoclast structure and function by FAK family kinases.	PTK2B PTK2	1.81e-05	3	86	2	22941736
Pubmed	Epidermal growth factor stimulates matrix metalloproteinase-9 expression and invasion in human follicular thyroid carcinoma cells through Focal adhesion kinase.	EGF PTK2	1.81e-05	3	86	2	17397984
Pubmed	Cooperation between c-Met and focal adhesion kinase family members in medulloblastoma and implications for therapy.	PTK2B PTK2	1.81e-05	3	86	2	22188814
Pubmed	p125Fak focal adhesion kinase is a substrate for the insulin and insulin-like growth factor-I tyrosine kinase receptors.	INSR PTK2	1.81e-05	3	86	2	9507031
Pubmed	FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.	PTK2B PTK2	1.81e-05	3	86	2	16202977
Pubmed	THBS4 promotes HCC progression by regulating ITGB1 via FAK/PI3K/AKT pathway.	THBS4 PTK2	1.81e-05	3	86	2	32567740
Pubmed	A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.	CNTN4 KIAA0825	1.81e-05	3	86	2	22318345
Pubmed	PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility.	PTK2B PTK2	1.81e-05	3	86	2	18195107
Pubmed	LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.	PTK2B PTK2	1.81e-05	3	86	2	28699640
Pubmed	Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor.	PTK2B PTK2	1.81e-05	3	86	2	16760434
Pubmed	Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate.	PTK2B PTK2	1.81e-05	3	86	2	20805505
Pubmed	Regulation of heterochromatin remodelling and myogenin expression during muscle differentiation by FAK interaction with MBD2.	PTK2B PTK2	1.81e-05	3	86	2	19661918
Pubmed	Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages.	PTK2B PTK2	3.61e-05	4	86	2	11668182
Pubmed	Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survival.	PTK2B PTK2	3.61e-05	4	86	2	19880522
Pubmed	A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.	PTK2B PTK2	3.61e-05	4	86	2	19435801
Pubmed	Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions.	PTK2B PTK2	3.61e-05	4	86	2	9422762
Pubmed	v-Src rescues actin-based cytoskeletal architecture and cell motility and induces enhanced anchorage independence during oncogenic transformation of focal adhesion kinase-null fibroblasts.	PTK2B PTK2	3.61e-05	4	86	2	14500722
Pubmed	The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation.	PTK2B FGFR3	3.61e-05	4	86	2	15105428
Pubmed	The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.	EGF ACKR3	3.61e-05	4	86	2	20388803
Pubmed	FAK regulates tyrosine phosphorylation of CAS, paxillin, and PYK2 in cells expressing v-Src, but is not a critical determinant of v-Src transformation.	PTK2B PTK2	3.61e-05	4	86	2	11787067
Pubmed	Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-β therapy in multiple sclerosis patients.	DENND3 PTK2	3.61e-05	4	86	2	21502966
Pubmed	Involvement of ROS-alpha v beta 3 integrin-FAK/Pyk2 in the inhibitory effect of melatonin on U251 glioma cell migration and invasion under hypoxia.	PTK2B PTK2	3.61e-05	4	86	2	25889845
Pubmed	Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion.	PTK2B PTK2	3.61e-05	4	86	2	9442086
Pubmed	Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2.	PTK2B PTK2	3.61e-05	4	86	2	12794117
Pubmed	Leupaxin is a critical adaptor protein in the adhesion zone of the osteoclast.	PTK2B PTK2	3.61e-05	4	86	2	12674328
Pubmed	Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.	DNAH5 DNAH11	3.61e-05	4	86	2	18492703
Pubmed	Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins.	PTK2B PTK2	3.61e-05	4	86	2	10980697
Pubmed	Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.	THBS3 THBS4	3.61e-05	4	86	2	6338048
Pubmed	Dot far-western blot analysis of relative binding affinities of the Src homology 3 domains of Efs and its related proteins.	PTK2B PTK2	3.61e-05	4	86	2	9750131
Pubmed	FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice.	ACKR3 FGFR3	3.61e-05	4	86	2	31662319
Pubmed	FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β.	PTK2B PTK2	3.61e-05	4	86	2	26274564
Pubmed	Arrestin 3 mediates endocytosis of CCR7 following ligation of CCL19 but not CCL21.	ARR3 CCL21	3.61e-05	4	86	2	18802075
Pubmed	The protein tyrosine kinase family of the human genome.	PTK2B INSR FGFR3 PTK2	5.52e-05	83	86	4	11114734
Pubmed	Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.	THBS3 THBS4	6.01e-05	5	86	2	30622267
Pubmed	Vascular endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and related adhesion focal tyrosine kinase.	PTK2B PTK2	6.01e-05	5	86	2	12844492
Pubmed	High prevalence of respiratory ciliary dysfunction in congenital heart disease patients with heterotaxy.	DNAH5 DNAH11	6.01e-05	5	86	2	22499950
Pubmed	DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.	DNAH5 DNAH11	6.01e-05	5	86	2	26909801
Pubmed	Ethnicity-Based Variations in Focal Adhesion Kinase Signaling in Glioblastoma Gene Expression: A Study of the Puerto Rican Hispanic Population.	PTK2B PTK2	6.01e-05	5	86	2	38732165
Pubmed	A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation.	PTK2B PTK2	6.01e-05	5	86	2	23936270
Pubmed	Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.	THBS3 THBS4	6.01e-05	5	86	2	18467703
Pubmed	Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.	PTK2B PTK2	6.01e-05	5	86	2	16391003
Pubmed	Inhibition of the catalytic activity of cell adhesion kinase beta by protein-tyrosine phosphatase-PEST-mediated dephosphorylation.	PTK2B PTK2	6.01e-05	5	86	2	11337490
Pubmed	HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis.	ARHGEF10 EXOC1 CDC27 ZRANB1	6.63e-05	87	86	4	33711283
Pubmed	Mechanical loading in osteocytes induces formation of a Src/Pyk2/MBD2 complex that suppresses anabolic gene expression.	PTK2B PTK2	9.01e-05	6	86	2	24841674
Pubmed	CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.	DNAH5 DNAH11	9.01e-05	6	86	2	33347437
Pubmed	Epidermal growth factor stimulates RSK2 activation through activation of the MEK/ERK pathway and src-dependent tyrosine phosphorylation of RSK2 at Tyr-529.	EGF FGFR3	9.01e-05	6	86	2	18156174
Pubmed	The atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamics.	PTK2B PTK2	9.01e-05	6	86	2	18086875
Pubmed	Protein tyrosine kinase 2 beta (PTK2B), but not focal adhesion kinase (FAK), is expressed in a sexually dimorphic pattern in developing mouse gonads.	PTK2B PTK2	9.01e-05	6	86	2	20737507
Pubmed	Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration.	PTK2B PTK2	9.01e-05	6	86	2	9774338
Pubmed	Characterization of a focal adhesion protein, Hic-5, that shares extensive homology with paxillin.	PTK2B PTK2	9.01e-05	6	86	2	9858471
Pubmed	Pyk2/ERK 1/2 mediate Sp1- and c-Myc-dependent induction of telomerase activity by epidermal growth factor.	PTK2B EGF	9.01e-05	6	86	2	18365874
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ERCC6L NCBP1 TNKS1BP1 EXOC1 BTAF1 TNFAIP2 PSMD13 CDC27	9.90e-05	582	86	8	20467437
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH5 DNAH11	1.26e-04	7	86	2	31178125
Pubmed	Knock-in mutation reveals an essential role for focal adhesion kinase activity in blood vessel morphogenesis and cell motility-polarity but not cell proliferation.	PTK2B PTK2	1.68e-04	8	86	2	20442405
Pubmed	Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.	THBS3 THBS4	1.68e-04	8	86	2	24460873
Pubmed	Regulation of Skp2 levels by the Pim-1 protein kinase.	PIM1 CDC27	1.68e-04	8	86	2	20663873
Pubmed	Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.	THBS3 THBS4 CHRD DGKA FGFR3	1.79e-04	210	86	5	16537572
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SMG1 ERCC6L DGKA CC2D1B BTAF1 TNFAIP2 DENND3 PTK2	2.10e-04	650	86	8	38777146
Pubmed	SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance.	EGF TNFAIP2	2.15e-04	9	86	2	20157331
Pubmed	Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting.	PTK2B PTK2	2.15e-04	9	86	2	12629171
Pubmed	Multiple mouse chromosomal loci for dynein-based motility.	DNAH12 PIM1 DNAH5	2.19e-04	47	86	3	8812413
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SMG1 CLTCL1 KIAA0825 SPEF2 LMLN DGKA CC2D1B NCBP1 POLQ TTC3 CDC27 DOP1A	2.21e-04	1442	86	12	35575683
Pubmed	Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development.	PTK2B PTK2	3.28e-04	11	86	2	19776009
Pubmed	Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.	PTK2B PTK2	3.28e-04	11	86	2	16374517
Pubmed	Immunohistochemical study of genesis of the mouse oral vestibule.	EGF FGFR3	3.93e-04	12	86	2	14964469
Cytoband	10q23	DLG5 LRIT1	2.67e-04	13	86	2	10q23
GeneFamily	Dyneins, axonemal	DNAH12 DNAH5 DNAH11	1.76e-05	17	55	3	536
GeneFamily	Fibronectin type III domain containing	CNTN4 PTPRZ1 INSR LRIT1	1.42e-03	160	55	4	555
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 CNTNAP2 FER1L5 DNAH5 CFAP157 DNAH11	5.15e-08	176	86	7	dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 KIAA0825 SPEF2 LMLN DNAH5 CFAP157 DNAH11	1.11e-07	197	86	7	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DNAH12 SPEF2 CNTNAP2 DNAH5 CFAP157 DNAH11	4.87e-07	151	86	6	8216462e723fec2797387929dde095370947e10a
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 KIAA0825 SPEF2 LMLN CFAP157 DNAH11	9.42e-07	169	86	6	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|lymph-node_spleen / Manually curated celltypes from each tissue	THBS4 CLTCL1 ERCC6L FADS2 CCL21 POLQ	1.55e-06	184	86	6	f93373fcde5c31f4ffe67ca0f3ea7f4e906dc88b
ToppCell	P07-Epithelial-airway_epithelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DNAH12 SPEF2 CLDN4 DNAH5 CFAP157 DNAH11	1.55e-06	184	86	6	a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCell	P07-Epithelial-airway_epithelial_cell-club_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DNAH12 SPEF2 CLDN4 DNAH5 CFAP157 DNAH11	1.55e-06	184	86	6	ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCell	COVID-19-lung-Secretory\|lung / Disease (COVID-19 only), tissue and cell type	CNTN4 PTPRZ1 INSR FGFR3 ERN2 DNAH5	1.81e-06	189	86	6	84d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCell	15-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	DNAH12 CMTM4 FGFR3 DNAH5 CFAP157 DNAH11	1.98e-06	192	86	6	9cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell	ASK428-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH12 SPEF2 LXN DNAH5 CFAP157 DNAH11	1.98e-06	192	86	6	356ebddd03aec341b79890977edb8ff0804999a1
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH12 KIAA0825 SPEF2 DNAH5 CFAP157 DNAH11	2.29e-06	197	86	6	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 CLDN4 DNAH5 CFAP157 DNAH11	2.29e-06	197	86	6	d83c61d2b5742e463122e1a98c7197a5b5b3d41b
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 ERN2 DNAH5 CFAP157 DNAH11	2.36e-06	198	86	6	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	DLG5 EGF PTPRZ1 SBF2 INSR ERN2	2.50e-06	200	86	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Ciliated_cells-B-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	1.66e-05	164	86	5	fd30c55d0d75ef8b9396435d836187168095152b
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	1.92e-05	169	86	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	Ciliated_cells-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	PTPN5 DNAH12 SPEF2 DNAH5 DNAH11	1.97e-05	170	86	5	8b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPN5 RUBCNL CLDN4 FGFR3 DNAH11	2.27e-05	175	86	5	9a96794df049d8228fea57c1584c160191d36b56
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	2.53e-05	179	86	5	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	2.60e-05	180	86	5	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	2.74e-05	182	86	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	2.74e-05	182	86	5	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	2.96e-05	185	86	5	f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	2.96e-05	185	86	5	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	NS-critical-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.04e-05	186	86	5	76033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS4 PTPRZ1 FADS2 FGFR3 LXN	3.04e-05	186	86	5	ac7a84b11b4550c4ac01eab370dc8ab88e4fb72b
ToppCell	21-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.12e-05	187	86	5	1a2178a195d078d1963947b327c6d0d4f2f48341
ToppCell	multiciliated\|World / shred by cell class for bronchial biopsy	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.20e-05	188	86	5	6833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell	21-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.20e-05	188	86	5	803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.20e-05	188	86	5	82c006f43c93f4a867953a446864f02b44536a23
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.20e-05	188	86	5	da59b5c0a4b11690a39a964c1a0a83e66aa0972b
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.28e-05	189	86	5	02c6128a9ab5818e0881dcadafdad5f08b9a67cf
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.28e-05	189	86	5	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.28e-05	189	86	5	164ea92ff6a1aa2ead1c9b8f64f99a9d65437232
ToppCell	Multiciliated\|World / shred by cell class for nasal brushing	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.28e-05	189	86	5	34b110aef839376228c5a403a6b5047a945f472b
ToppCell	PND10-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.28e-05	189	86	5	a85099bd598a27ee64ee0664d051d89fa8d62fc9
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.28e-05	189	86	5	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH12 KIAA0825 SPEF2 DNAH5 DNAH11	3.28e-05	189	86	5	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.36e-05	190	86	5	9ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell	Nasal_Brush-Epithelial-Ciliated_2\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.36e-05	190	86	5	833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCell	Ciliated_cells-B\|World / lung cells shred on cell class, cell subclass, sample id	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.36e-05	190	86	5	7031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCell	Ciliated_cells-A\|World / lung cells shred on cell class, cell subclass, sample id	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.36e-05	190	86	5	cd87731aaa7d252424f79cfce9f7931457f17bdf
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	7b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	9f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCell	Control-Epithelial-Ciliated_cells\|Control / Condition, Lineage and Cell class	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	b4e335e798c9617356b8e24412f9270c42dce656
ToppCell	BAL-Control-Epithelial-Epithelial-Ciliated\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	c4b223b33c020a064f576711a3d700eb60a2d737
ToppCell	BAL-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	5129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCell	ASK428-Epithelial-Ciliated\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	0c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	Control-Epithelial\|Control / Disease group,lineage and cell class （2021.01.30）	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	b78547dae8328244a47c83346447bdd787efbcae
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	(12)_SLC16A7+\|World / shred by cell type by condition	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCell	BAL-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCell	Control-Epithelial-Ciliated\|Control / Disease group,lineage and cell class （2021.01.30）	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCell	Control-Epithelial\|Control / Condition, Lineage and Cell class	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	6228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.45e-05	191	86	5	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.54e-05	192	86	5	be592e661367affced9ebe80849b466e6adb3a34
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PTPRZ1 ACKR3 FGFR3 TNFAIP2 ERN2	3.54e-05	192	86	5	5d24bb6c6c17a6b803b241d065b31896a7d86c37
ToppCell	390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	PTPRZ1 ACKR3 FGFR3 TNFAIP2 ERN2	3.54e-05	192	86	5	c6795ceba90f1a5d441dff92a737b9c7d28b06b0
ToppCell	multiciliated\|World / shred by cell class for turbinate	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.54e-05	192	86	5	0f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 CLDN4 DNAH5 CFAP157 DNAH11	3.54e-05	192	86	5	6c269d2426f76559d2ed3bf2169eb4be5fc7ad6d
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.62e-05	193	86	5	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	Bronchial_Brush\|World / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.62e-05	193	86	5	3e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH12 KIAA0825 SPEF2 DNAH5 DNAH11	3.62e-05	193	86	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPRZ1 SPEF2 DNAH5 CFAP157 DNAH11	3.62e-05	193	86	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	15-Trachea-Epithelial-Multiciliated_cell\|Trachea / Age, Tissue, Lineage and Cell class	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.62e-05	193	86	5	aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH12 KIAA0825 SPEF2 DNAH5 DNAH11	3.62e-05	193	86	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	Bronchial_Biopsy-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.62e-05	193	86	5	0b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.62e-05	193	86	5	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.62e-05	193	86	5	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.71e-05	194	86	5	b4ce60c06568123008b1081d644733cb91c28f51
ToppCell	NS-critical-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.71e-05	194	86	5	1ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	INSR CLDN4 FGFR3 ERN2 PTK2	3.71e-05	194	86	5	0cd4363627acd419e00d6d32f6dce10430aa6487
ToppCell	Bronchial_Brush-Epithelial-Ciliated_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.71e-05	194	86	5	7a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	INSR CLDN4 FGFR3 ERN2 PTK2	3.71e-05	194	86	5	a58841b34efe673671a9a059238e044a7254b279
ToppCell	ASK452-Epithelial-Ciliated\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.71e-05	194	86	5	5aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.71e-05	194	86	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.71e-05	194	86	5	a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCell	COVID-19-Epithelial-Ciliated_cells\|COVID-19 / Condition, Lineage and Cell class	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.71e-05	194	86	5	43be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	79dc031258579ea328181dda33710dd897f1064a
ToppCell	18-Airway-Epithelial-Multiciliated_cell\|Airway / Age, Tissue, Lineage and Cell class	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	3441381759cd00d125752401dc99b78be1c78f88
ToppCell	NS-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	34e37cff4849696ca4ba5dd8fd2cf98fed8bc912
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	moderate-Epithelial-Ciliated\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCell	BL-critical-LOC-Epithelial-Ciliated\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	07a6bcef6af93ed87df455dee624037cb75e011a
ToppCell	cellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.81e-05	195	86	5	e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.90e-05	196	86	5	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	critical-Epithelial-Ciliated\|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.90e-05	196	86	5	27b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.90e-05	196	86	5	686a5a0ddb00929842c1c98445c59edfcc9a8a04
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.90e-05	196	86	5	67aefc480714e4b8c9ae53c036efdc07ec6f94af
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ARHGEF10 CMTM4 BEND7 LMLN FGFR3	3.90e-05	196	86	5	7be50b9156394dea44d7b8b476d4dd516abfafae
ToppCell	BAL-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.90e-05	196	86	5	ca56311edc6788e032e7635fa69b1e07035202b5
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated-diff\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH12 SPEF2 DNAH5 CFAP157 DNAH11	3.90e-05	196	86	5	9a91a6e5f93ce3bb5a0fc63677553f4c2df95c43
Drug	BPIQ-I	PTK2B EGF PTK2	5.91e-06	10	85	3	CID000002427
Drug	Norethynodrel [68-23-5]; Down 200; 13.4uM; HL60; HT_HG-U133A	PTK2B THBS4 COPS8 NCBP1 TTC38 ADCY3 DOP1A	7.97e-06	193	85	7	1860_DN
Drug	Alexidine dihydrochloride [22573-93-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	ERCC6L ARHGEF10 GLE1 FGFR3 POLQ ERN2 TTC38	8.24e-06	194	85	7	4721_DN
Drug	Gossypol [303-45-7]; Down 200; 7.8uM; MCF7; HT_HG-U133A	ERCC6L ARHGEF10 CNTNAP2 FADS2 FGFR3 ERN2 DOP1A	9.41e-06	198	85	7	4762_DN
Drug	1,2,4,5-benzenetetramine	PTK2B PTK2	1.38e-05	2	85	2	CID000078260
Drug	ALK5 inhibitor	PTK2B PTK2	1.38e-05	2	85	2	CID000449054
Drug	vanadyl	PTK2B EGF PTPRZ1 INSR DNAH5 PTK2 LRIT1 DNAH11	1.95e-05	307	85	8	CID000061671
Drug	Rgd Peptide	CNTN4 PTK2B THBS3 THBS4 EGF LMLN PTK2	3.17e-05	239	85	7	CID000104802
Disease	Agouti-related protein measurement	ABCA6 PLEKHG4 CMTM4 CDH16	9.26e-07	27	82	4	EFO_0008016
Disease	low density lipoprotein cholesterol measurement, physical activity	ABCA6 CNTNAP2 FADS2 DNAH11	3.50e-05	66	82	4	EFO_0003940, EFO_0004611
Disease	Kartagener syndrome (is_implicated_in)	DNAH5 DNAH11	4.56e-05	4	82	2	DOID:0050144 (is_implicated_in)
Disease	sleep efficiency	BEND7 CNTNAP2	7.59e-05	5	82	2	EFO_0803364
Disease	Giant Cell Glioblastoma	EGF PIM1 FGFR3 PTK2	9.03e-05	84	82	4	C0334588
Disease	procollagen C-endopeptidase enhancer 1 measurement	FADS2 DNAH11	1.14e-04	6	82	2	EFO_0801920
Disease	Rheumatoid Arthritis	ACKR3 B3GNT2 TNFAIP2 CCL21 PTK2	1.27e-04	174	82	5	C0003873
Disease	FEV/FEC ratio	USP34 THBS3 DNAH12 COPS8 SPEF2 SBF2 CNTNAP2 FGFR3 DNAH5 ADCY3 DENND3 PTK2	1.44e-04	1228	82	12	EFO_0004713
Disease	response to interferon-beta	DENND3 PTK2	1.59e-04	7	82	2	GO_0035456
Disease	Glioblastoma Multiforme	EGF PIM1 TAF1L PTK2	2.65e-04	111	82	4	C1621958
Disease	Todd Paralysis	TRPM7 CHRND	2.71e-04	9	82	2	C0234544
Disease	Paralysed	TRPM7 CHRND	2.71e-04	9	82	2	C0522224
Disease	gallbladder neoplasm	CNTN4 KIAA0825	2.71e-04	9	82	2	EFO_0004606
Disease	Primary Ciliary Dyskinesia	SPEF2 DNAH5 DNAH11	3.07e-04	47	82	3	C4551720
Disease	nephritis (implicated_via_orthology)	PTK2B PTK2	3.38e-04	10	82	2	DOID:10952 (implicated_via_orthology)
Disease	glycosaminoglycan xylosylkinase measurement	B3GNT2 FADS2	3.38e-04	10	82	2	EFO_0801647
Disease	intercellular adhesion molecule 5 measurement	MRPL4 ABCA6	5.83e-04	13	82	2	EFO_0008164
Disease	Kartagener syndrome (implicated_via_orthology)	DNAH5 DNAH11	6.79e-04	14	82	2	DOID:0050144 (implicated_via_orthology)
Disease	level of Phosphatidylethanolamine (18:1_18:1) in blood serum	CNTNAP2 FADS2	6.79e-04	14	82	2	OBA_2045142
Disease	Stuttering	USP34 FUT11 CNTNAP2 DENND3	6.90e-04	143	82	4	HP_0025268
Disease	Antihypertensive use measurement	KIAA0825 SBF2 INSR ADCY3 CDH16	8.74e-04	265	82	5	EFO_0009927
Disease	level of Phosphatidylcholine (18:0_18:2) in blood serum	FADS2 RWDD3	8.93e-04	16	82	2	OBA_2045090
Disease	Colorectal Neoplasms	ABCA6 TRPM7 ACKR3 FADS2 FGFR3	1.06e-03	277	82	5	C0009404
Disease	myeloid white cell count	USP34 PTK2B DLG5 EGF ACKR3 BEND7 SBF2 FADS2 RWDD3	1.17e-03	937	82	9	EFO_0007988
Disease	Congenital hernia of foramen of Morgagni	PIM1 INSR	1.27e-03	19	82	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	PIM1 INSR	1.27e-03	19	82	2	C0265700
Disease	primary ciliary dyskinesia (implicated_via_orthology)	SPEF2 DNAH5	1.27e-03	19	82	2	DOID:9562 (implicated_via_orthology)
Disease	Lung diseases	INSR DNAH5 DNAH11	1.35e-03	78	82	3	C0024115
Disease	total iron binding capacity	B3GNT2 LMLN FADS2	1.35e-03	78	82	3	EFO_0006334
Disease	Glioblastoma	EGF PIM1 PTK2	1.40e-03	79	82	3	C0017636
Disease	Congenital diaphragmatic hernia	PIM1 INSR	1.55e-03	21	82	2	C0235833
Disease	Infiltrating duct carcinoma of female breast	SMG1 TRPM7	1.55e-03	21	82	2	C3165106
Disease	white matter hyperintensity measurement	PGPEP1L SPEF2 SBF2 DENND3 PTK2	1.56e-03	302	82	5	EFO_0005665
Disease	Bronchiectasis	DNAH5 DNAH11	1.70e-03	22	82	2	C0006267
Disease	alpha-linolenic acid measurement	KIAA0825 FADS2	2.20e-03	25	82	2	EFO_0007759
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	ABCA6 FADS2 DNAH11	2.68e-03	99	82	3	EFO_0004611, EFO_0007878
Disease	triacylglycerol 54:7 measurement	CNTN4 FADS2	2.75e-03	28	82	2	EFO_0010425
Disease	glucose metabolism disease (implicated_via_orthology)	INSR DGKA	2.75e-03	28	82	2	DOID:4194 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DMVWLPEIVLENNND	CHRND	106	Q07001
HQEELAPTVMVWQIP	ARHGEF10	1351	O15013
ADPKELWVQQLMQHL	CCL21	76	O00585
LWVQQLMQHLDKTPS	CCL21	81	O00585
QENVLWPMLTLREHL	ABCA6	1361	Q8N139
PNWIQKINDIHVAME	CNTN4	316	Q8IWV2
VGHVETWLLQLEQTM	DNAH11	1696	Q96DT5
DCEHVQPPQWLQTLM	DOP1A	781	Q5JWR5
WVVEHVLPHMQENQP	GLE1	51	Q53GS7
QWQHPFVPILSDQML	DENND3	241	A2RUS2
VTFQPWHKEMLQQLL	CFAP157	391	Q5JU67
AQPLQLQAWMDREVH	ARR3	191	P36575
MEWINATLLPEHIVV	PARVG	51	Q9HBI0
LMRHKAVWINPQDVQ	RUBCNL	46	Q9H714
MVWQEHTPIIVMITN	PTPN5	386	P54829
PDVNMLHVFVLGEWQ	FADS2	231	O95864
IWADVIVNSVPMNLQ	PARP15	101	Q460N3
LVNVQQVWQDSHMFP	KIAA0825	461	Q8IV33
FEVWRNHPQMIAVLV	NCBP1	591	Q09161
EWFPQLHRIMQLAVV	SBF2	1381	Q86WG5
WILFVMRQQQPQVVE	ERN2	446	Q76MJ5
QVLPVSIQMNGWIHD	LMLN	576	Q96KR4
IWEDHQPQLVVHVGM	PGPEP1L	41	A6NFU8
HMDRWSVEVIPQQTE	DGKA	496	P23743
LAMVNQEQNKVLWIP	DLG5	1901	Q8TDM6
SPLVPIQQEWLDHML	DNAH12	106	Q6ZR08
IQQEWLDHMLRLIPE	DNAH12	111	Q6ZR08
LLPQVQTNTLQEEMW	GOLGA6L2	261	Q8N9W4
IFENNVVHLMWQEPK	INSR	861	P06213
VHMTWVQPRVLDLQQ	PSMD13	331	Q9UNM6
WEHNVEVIVMITNLV	PTPRZ1	1816	P23471
WDHNAQLVVMIPDGQ	PTPRZ1	2111	P23471
QLMRLPQELIVSWAH	LRIT1	166	Q9P2V4
QMWSLHNIVPEIDNA	ETAA1	236	Q9NY74
HLPVMKQLVQQLEQW	GPN3	116	Q9UHW5
MIQQHQEWLEDLVIR	BTAF1	331	O14981
VVFVEHDWNPMRDLQ	BTAF1	1721	O14981
VCQHVMPLNERQEWI	EFCAB7	606	A8K855
LWQQRALDPPHQMEL	EGF	1191	P01133
VRDWMPNNHSVILID	FUT11	311	Q495W5
ILQQDLVEMGVQWNP	POLQ	886	O75417
QVEMWPLLTAEQNHL	F8A1;	341	P23610
QDVQMVTENWLVLEP	CC2D1B	841	Q5T0F9
VVSLVQHNQWPMGEL	ACKR3	101	P25106
RWNEALVTNMLPEHV	ADCY3	886	O60266
LIQNFMPEDISVQWL	IGHE	346	P01854
MPEDISVQWLHNEVQ	IGHE	351	P01854
MAEPWEEQHLVLLNN	BEND7	446	Q8N7W2
HQWSETVQPIMEALR	COPS8	96	Q99627
VWTIVSHDLQMQTPV	CNTNAP2	636	Q9UHC6
NLLQVVWHSMQDEFI	EXOC1	841	Q9NV70
LRHQQWSLVMESVVP	FGFR3	206	P22607
EIHWLHPQMTVGEVQ	PTK2B	101	Q14289
PIQNRWLVHIMSDIA	GPR139	256	Q6DWJ6
MTVLQEPVQAAIWQA	CDC27	1	P30260
QVEHWQSFLALVNMI	IPO13	326	O94829
IIPVVVSHNAQMWQL	CDH16	741	O75309
MPIINEWGDQVTNEI	DNAH5	2661	Q8TE73
NHVLLIMPTNLINTW	ERCC6L	146	Q2NKX8
SIQELEIHNMSWPRL	PRAMEF13	206	Q5VWM6
NIASQEIIPWQMQVL	LXN	186	Q9BS40
FEEIQNHPWMQDVLL	PIM1	281	P11309
NHPWMQDVLLPQETA	PIM1	286	P11309
WMHLTQPELQELTSL	SPEF2	1511	Q9C093
VDMSWIPQETLNQIN	SSR1	251	P43307
KNIDHMLWLEQPENI	PTRHD1	101	Q6GMV3
PRLDILHQVAMWQKN	MRPL4	91	Q9BYD3
HMQTQTDNPIWNQIL	FER1L5	361	A0AVI2
QTEVLMQQVLDSPWL	PLEKHG4	376	Q58EX7
PTSAMVLQQHRLQIW	PIWIL2	346	Q8TC59
NIIQHSIPAMELWQP	TAF1L	606	Q8IZX4
HRPQEIAMWQPNVED	PTK2	776	Q05397
QWQHEDLLINRPQAM	SMG1	3201	Q96Q15
HSMLPIQQLQEWGVE	SHPK	411	Q9UHJ6
QEMIDIWSQLQSAHL	B3GNT2	381	Q9NY97
MVIVPVSWTAHNIIQ	CLDN4	131	O14493
QTWLLEMNLVHAPQV	CLTCL1	581	P53675
MRIPQINWNLTDLVN	CMTM4	111	Q8IZR5
EVLPNLTVQEMDWLV	CHRD	361	Q9H2X0
WVFPQEMVLEIHQLF	CLUHP3	66	Q96NS8
IDPNWVVLNQGMEIV	THBS4	746	P35443
SEPMVHELVLWIQQN	RWDD3	96	Q9Y3V2
MEQNWQVPQDTLSLL	TNFAIP2	436	Q03169
QMDWTQDLAPQNVEL	TNKS1BP1	1341	Q9C0C2
TNIPHVQMVAIQVSW	TTC3	1456	P53804
VQMVAIQVSWNIIHQ	TTC3	1461	P53804
RWTTEQHMPEVEVQV	SNURFL	11	B1AK76
QIDPNWVVLNQGMEI	THBS3	741	P49746
WEQILQDHPTDMLAL	TTC38	131	Q5R3I4
WLQPEMHSKEQILEL	ZKSCAN4	81	Q969J2
NIRIWLHIPAVMQHI	USP34	251	Q70CQ2
HEPTWAQQLLQEMKT	TMEM234	36	Q8WY98
VQMEQLPSVQEWIVI	TRPM7	876	Q96QT4
RNHPLVTQMVEKWLD	ZRANB1	671	Q9UGI0