Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	insulin receptor activity	INSRR IGF1R	8.83e-05	3	109	2	GO:0005009
GeneOntologyMolecularFunction	6-phosphofructokinase activity	PFKL PFKM	8.83e-05	3	109	2	GO:0003872
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2	1.76e-04	4	109	2	GO:0005219
GeneOntologyMolecularFunction	calcium ion binding	HSPG2 CD248 DSG2 ENPP3 ADGRV1 FLG2 TENM2 RYR1 RYR2 NELL2 FAT1 ITSN2 PCDHGC3	2.23e-04	749	109	13	GO:0005509
GeneOntologyMolecularFunction	fructose-6-phosphate binding	PFKL PFKM	2.92e-04	5	109	2	GO:0070095
GeneOntologyMolecularFunction	fructose binding	PFKL PFKM	4.37e-04	6	109	2	GO:0070061
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2	4.37e-04	6	109	2	GO:0048763
GeneOntologyMolecularFunction	protease binding	HSPG2 NDUFS7 RYR1 SERPINF2 PZP ALPP	4.78e-04	181	109	6	GO:0002020
GeneOntologyMolecularFunction	phosphofructokinase activity	PFKL PFKM	6.09e-04	7	109	2	GO:0008443
GeneOntologyMolecularFunction	transcription coregulator binding	HDAC5 STAT6 MED25 BSN CNOT2	1.03e-03	140	109	5	GO:0001221
GeneOntologyBiologicalProcess	clathrin-dependent endocytosis	FNBP1L ITGA4 AP2M1 ITSN2 SIGLEC1	1.05e-05	53	113	5	GO:0072583
GeneOntologyCellularComponent	6-phosphofructokinase complex	PFKL PFKM	8.51e-05	3	112	2	GO:0005945
GeneOntologyCellularComponent	insulin receptor complex	INSRR IGF1R	1.70e-04	4	112	2	GO:0005899
MousePheno	skeletal muscle fiber degeneration	FLNC PFKM RYR1 EPG5	9.24e-06	21	91	4	MP:0009412
MousePheno	skeletal muscle degeneration	FLNC PFKM RYR1 EPG5	4.05e-05	30	91	4	MP:0009415
Domain	Growth_fac_rcpt_	HSPG2 FRAS1 CD248 INSRR IGFBPL1 NELL2 FAT1 IGF1R	4.22e-06	156	111	8	IPR009030
Domain	ConA-like_dom	HSPG2 ADGRV1 RYR1 RYR2 NELL2 FAT1 NEURL4 SPSB2	4.93e-05	219	111	8	IPR013320
Domain	6-Pfructokinase_euk	PFKL PFKM	1.05e-04	3	111	2	IPR009161
Domain	Ryanodine_rcpt	RYR1 RYR2	1.05e-04	3	111	2	IPR003032
Domain	PHOSPHOFRUCTOKINASE	PFKL PFKM	1.05e-04	3	111	2	PS00433
Domain	Phosphofructokinase_CS	PFKL PFKM	1.05e-04	3	111	2	IPR015912
Domain	Ryanrecept_TM4-6	RYR1 RYR2	1.05e-04	3	111	2	IPR009460
Domain	PFK	PFKL PFKM	1.05e-04	3	111	2	PF00365
Domain	ATP_PFK	PFKL PFKM	1.05e-04	3	111	2	IPR022953
Domain	RyR	RYR1 RYR2	1.05e-04	3	111	2	PF02026
Domain	Tyr_kinase_insulin-like_rcpt	INSRR IGF1R	1.05e-04	3	111	2	IPR016246
Domain	RR_TM4-6	RYR1 RYR2	1.05e-04	3	111	2	PF06459
Domain	Phosphofructokinase_dom	PFKL PFKM	1.05e-04	3	111	2	IPR000023
Domain	Ryan_recept	RYR1 RYR2	1.05e-04	3	111	2	IPR013333
Domain	Furin_repeat	FRAS1 INSRR IGF1R	1.56e-04	18	111	3	IPR006212
Domain	FU	FRAS1 INSRR IGF1R	1.56e-04	18	111	3	SM00261
Domain	EGF	HSPG2 FRAS1 CD248 ADAM15 TENM2 NELL2 FAT1	5.12e-04	235	111	7	SM00181
Domain	IGc2	HSPG2 LRFN3 HAPLN4 IGFBPL1 FCRL1 SIGLEC1 LRIT1	5.12e-04	235	111	7	SM00408
Domain	Ig_sub2	HSPG2 LRFN3 HAPLN4 IGFBPL1 FCRL1 SIGLEC1 LRIT1	5.12e-04	235	111	7	IPR003598
Domain	RIH_assoc-dom	RYR1 RYR2	5.17e-04	6	111	2	IPR013662
Domain	Ins145_P3_rec	RYR1 RYR2	5.17e-04	6	111	2	PF08709
Domain	RIH_assoc	RYR1 RYR2	5.17e-04	6	111	2	PF08454
Domain	RIH_dom	RYR1 RYR2	5.17e-04	6	111	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	5.17e-04	6	111	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	5.17e-04	6	111	2	IPR015925
Domain	-	RYR1 RYR2	5.17e-04	6	111	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2	5.17e-04	6	111	2	PF01365
Domain	-	HSPG2 FLNA FLNC LRFN3 INSRR HAPLN4 IGFBPL1 TGM4 FCRL1 IGF1R SIGLEC1 LRIT1	5.78e-04	663	111	12	2.60.40.10
Domain	EGF-like_dom	HSPG2 FRAS1 CD248 ADAM15 TENM2 NELL2 FAT1	7.20e-04	249	111	7	IPR000742
Domain	Recep_L_domain	INSRR IGF1R	7.21e-04	7	111	2	PF01030
Domain	Furin-like	INSRR IGF1R	7.21e-04	7	111	2	PF00757
Domain	Rcpt_L-dom	INSRR IGF1R	7.21e-04	7	111	2	IPR000494
Domain	Furin-like_Cys-rich_dom	INSRR IGF1R	7.21e-04	7	111	2	IPR006211
Domain	-	INSRR IGF1R	7.21e-04	7	111	2	3.80.20.20
Domain	EGF_CA	HSPG2 CD248 TENM2 NELL2 FAT1	8.08e-04	122	111	5	SM00179
Domain	EGF-like_Ca-bd_dom	HSPG2 CD248 TENM2 NELL2 FAT1	8.70e-04	124	111	5	IPR001881
Domain	Calx_beta	FRAS1 ADGRV1	9.57e-04	8	111	2	SM00237
Domain	Ig_I-set	HSPG2 LRFN3 IGFBPL1 FCRL1 SIGLEC1 LRIT1	9.58e-04	190	111	6	IPR013098
Domain	I-set	HSPG2 LRFN3 IGFBPL1 FCRL1 SIGLEC1 LRIT1	9.58e-04	190	111	6	PF07679
Domain	Ig-like_fold	HSPG2 FLNA FLNC LRFN3 INSRR HAPLN4 IGFBPL1 TGM4 FCRL1 IGF1R SIGLEC1 LRIT1	1.00e-03	706	111	12	IPR013783
Domain	Calx_beta	FRAS1 ADGRV1	1.23e-03	9	111	2	IPR003644
Domain	PAZ	DICER1 AGO1	1.23e-03	9	111	2	PS50821
Domain	PAZ	DICER1 AGO1	1.23e-03	9	111	2	SM00949
Domain	PAZ	DICER1 AGO1	1.23e-03	9	111	2	PF02170
Domain	Calx-beta	FRAS1 ADGRV1	1.23e-03	9	111	2	PF03160
Domain	PAZ_dom	DICER1 AGO1	1.23e-03	9	111	2	IPR003100
Domain	MIR	RYR1 RYR2	1.53e-03	10	111	2	PF02815
Domain	IG_FLMN	FLNA FLNC	1.53e-03	10	111	2	SM00557
Domain	MIR_motif	RYR1 RYR2	1.53e-03	10	111	2	IPR016093
Domain	MIR	RYR1 RYR2	1.53e-03	10	111	2	PS50919
Domain	MIR	RYR1 RYR2	1.53e-03	10	111	2	SM00472
Domain	Laminin_G_2	HSPG2 NELL2 FAT1	1.72e-03	40	111	3	PF02210
Domain	Filamin	FLNA FLNC	1.86e-03	11	111	2	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNC	1.86e-03	11	111	2	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNC	1.86e-03	11	111	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNC	1.86e-03	11	111	2	IPR017868
Domain	Tyr_kinase_rcpt_2_CS	INSRR IGF1R	1.86e-03	11	111	2	IPR002011
Domain	RECEPTOR_TYR_KIN_II	INSRR IGF1R	2.22e-03	12	111	2	PS00239
Domain	LamG	HSPG2 NELL2 FAT1	2.27e-03	44	111	3	SM00282
Domain	-	HSPG2 ADGRV1 NELL2 FAT1	2.48e-03	95	111	4	2.60.120.200
Domain	EGF_3	HSPG2 CD248 ADAM15 TENM2 NELL2 FAT1	2.81e-03	235	111	6	PS50026
Domain	ADH_SHORT	RDH14 RDH13 DHRSX	3.86e-03	53	111	3	PS00061
Domain	EGF_1	HSPG2 CD248 ADAM15 TENM2 NELL2 FAT1	4.19e-03	255	111	6	PS00022
Domain	adh_short	RDH14 RDH13 DHRSX	4.28e-03	55	111	3	PF00106
Domain	SDR_fam	RDH14 RDH13 DHRSX	4.50e-03	56	111	3	IPR002347
Domain	EGF-like_CS	HSPG2 CD248 ADAM15 TENM2 NELL2 FAT1	4.69e-03	261	111	6	IPR013032
Domain	FN3	FLNC LRFN3 INSRR IGF1R LRIT1	4.97e-03	185	111	5	SM00060
Domain	Laminin_G	HSPG2 NELL2 FAT1	4.97e-03	58	111	3	IPR001791
Domain	EGF_2	HSPG2 CD248 ADAM15 TENM2 NELL2 FAT1	5.05e-03	265	111	6	PS01186
Domain	VWC_out	FRAS1 NELL2	5.60e-03	19	111	2	SM00215
Pathway	KEGG_PENTOSE_PHOSPHATE_PATHWAY	TKTL1 PFKL PFKM RPIA	1.94e-05	27	85	4	M1386
Pubmed	Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo.	SPRY1 HDAC5 ZIC1	9.33e-06	13	113	3	21143873
Pubmed	Insulin specifically regulates expression of liver and muscle phosphofructokinase isoforms.	PFKL PFKM	1.05e-05	2	113	2	29655163
Pubmed	Coexpression of insulin receptor-related receptor and insulin-like growth factor 1 receptor correlates with enhanced apoptosis and dedifferentiation in human neuroblastomas.	INSRR IGF1R	1.05e-05	2	113	2	14654552
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	1.05e-05	2	113	2	17259277
Pubmed	Isozyme analysis of human polymorphonuclear leukocyte phosphofructokinase from insulin resistant individuals.	PFKL PFKM	1.05e-05	2	113	2	8780720
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	1.05e-05	2	113	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	1.05e-05	2	113	2	26009179
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	1.05e-05	2	113	2	32899693
Pubmed	The molecular mechanism of the inherited phosphofructokinase deficiency associated with hemolysis and myopathy.	PFKL PFKM	1.05e-05	2	113	2	6444532
Pubmed	Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.	FLNA FLNC	1.05e-05	2	113	2	7689010
Pubmed	Sertoli cell Dicer is essential for spermatogenesis in mice.	DICER1 PLEKHA5	1.05e-05	2	113	2	19071104
Pubmed	Filamin A is required in injured axons for HDAC5 activity and axon regeneration.	FLNA HDAC5	1.05e-05	2	113	2	26157139
Pubmed	Filamin isogene expression during mouse myogenesis.	FLNA FLNC	1.05e-05	2	113	2	10679933
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	1.05e-05	2	113	2	15033925
Pubmed	Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.	SPRY1 DMRT1	1.05e-05	2	113	2	37070575
Pubmed	A novel structural unit in the N-terminal region of filamins.	FLNA FLNC	1.05e-05	2	113	2	24469451
Pubmed	Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins.	DICER1 AGO1	1.05e-05	2	113	2	17482383
Pubmed	Identification of B-cell-related HSPG2 and CDSN as susceptibility loci for Kawasaki disease.	HSPG2 CDSN	1.05e-05	2	113	2	37453912
Pubmed	The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription.	TENM2 ZIC1	1.05e-05	2	113	2	12783990
Pubmed	Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.	RYR1 RYR2	1.05e-05	2	113	2	30542613
Pubmed	Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.	RYR1 RYR2	1.05e-05	2	113	2	15280431
Pubmed	Expression of the ryanodine receptor isoforms in immune cells.	RYR1 RYR2	1.05e-05	2	113	2	11673493
Pubmed	B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.	RYR1 RYR2	1.05e-05	2	113	2	11673462
Pubmed	The glycolytic enzyme phosphofructokinase-1 assembles into filaments.	PFKL PFKM	1.05e-05	2	113	2	28646105
Pubmed	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.	RYR1 RYR2	1.05e-05	2	113	2	25370123
Pubmed	Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.	RYR1 RYR2	1.05e-05	2	113	2	18618700
Pubmed	Human transcription factor protein interaction networks.	HSPG2 HDAC5 UBR4 RPS13 ISL2 FLG2 SRCAP NPM3 FAT1 AP2M1 AGO1 ARID2 NFYC PABPC1L CNOT2 SENP5	1.57e-05	1429	113	16	35140242
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	RDH14 MRPL19 BRINP1 FNBP1L TENM2 ADCY1 DICER1 RYR2 AGO1	2.10e-05	462	113	9	31138677
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	HDAC5 WEE1 MCM7 FNBP1L SRCAP POLR3C ARID2 FBXO42 MED25 BSN	2.31e-05	588	113	10	38580884
Pubmed	Single nucleotide polymorphisms of microRNA machinery genes modify the risk of renal cell carcinoma.	DICER1 AGO1 NFYC	2.63e-05	18	113	3	19047128
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR2	3.13e-05	3	113	2	18403125
Pubmed	Functional expression of human mutant phosphofructokinase in yeast: genetic defects in French Canadian and Swiss patients with phosphofructokinase deficiency.	PFKL PFKM	3.13e-05	3	113	2	7825568
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR2	3.13e-05	3	113	2	7876312
Pubmed	IGFBPL1 is a master driver of microglia homeostasis and resolution of neuroinflammation in glaucoma and brain tauopathy.	IGFBPL1 IGF1R	3.13e-05	3	113	2	37527036
Pubmed	Isozymes of human phosphofructokinase: identification and subunit structural characterization of a new system.	PFKL PFKM	3.13e-05	3	113	2	6444721
Pubmed	Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.	RYR1 RYR2	3.13e-05	3	113	2	24123915
Pubmed	Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.	FLNA FLNC	3.13e-05	3	113	2	11038172
Pubmed	Genomic organization, 5'flanking region and tissue-specific expression of mouse phosphofructokinase C gene.	PFKL PFKM	3.13e-05	3	113	2	11137296
Pubmed	Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.	RYR1 RYR2	3.13e-05	3	113	2	23278119
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR2	3.13e-05	3	113	2	22948152
Pubmed	Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.	FLNA FLNC	3.13e-05	3	113	2	11102480
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR2	3.13e-05	3	113	2	10788707
Pubmed	Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.	FLNA FLNC	3.13e-05	3	113	2	17825253
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNC	3.13e-05	3	113	2	12393796
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR2	3.13e-05	3	113	2	7621815
Pubmed	Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.	FLNA FLNC	3.13e-05	3	113	2	9412467
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNC	3.13e-05	3	113	2	11153914
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR2	3.13e-05	3	113	2	10473538
Pubmed	Phosphofructokinase isozyme expression during myoblast differentiation.	PFKL PFKM	3.13e-05	3	113	2	2521854
Pubmed	Insulin receptor-related receptor as an extracellular alkali sensor.	INSRR IGF1R	3.13e-05	3	113	2	21641549
Pubmed	Biochemical and transcript level differences between the three human phosphofructokinases show optimisation of each isoform for specific metabolic niches.	PFKL PFKM	3.13e-05	3	113	2	33141153
Pubmed	EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.	DICER1 AGO1	3.13e-05	3	113	2	25656609
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNC	3.13e-05	3	113	2	11252955
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNA FLNC	3.13e-05	3	113	2	12704190
Pubmed	Phosphofructokinase (PFK) isozymes in man. I. Studies of adult human tissues.	PFKL PFKM	3.13e-05	3	113	2	156693
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR2	3.13e-05	3	113	2	18434746
Pubmed	Isozymes of human phosphofructokinase in blood cells and cultured cell lines: molecular and genetic evidence for a trigenic system.	PFKL PFKM	3.13e-05	3	113	2	6451249
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR2	3.13e-05	3	113	2	9204703
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR2	3.13e-05	3	113	2	21881589
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR2	3.13e-05	3	113	2	12213830
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR2	3.13e-05	3	113	2	9242641
Pubmed	Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.	RYR1 RYR2	3.13e-05	3	113	2	23454728
Pubmed	Insulin receptor-related (Irr) is expressed in pre-implantation embryos: a possible relationship to "growth factor Y" and sex determination.	INSRR IGF1R	3.13e-05	3	113	2	21681845
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR2	3.13e-05	3	113	2	25239916
Pubmed	Characterization of the enzymatic defect in late-onset muscle phosphofructokinase deficiency. New subtype of glycogen storage disease type VII.	PFKL PFKM	3.13e-05	3	113	2	2960695
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR2	3.13e-05	3	113	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR2	3.13e-05	3	113	2	11159936
Pubmed	Intracellular calcium release channel expression during embryogenesis.	RYR1 RYR2	3.13e-05	3	113	2	9986730
Pubmed	Hyperinsulinemic hypoglycemia with nesidioblastosis: histologic features and growth factor expression.	TGFBR3 IGF1R	3.13e-05	3	113	2	18931647
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR2	3.13e-05	3	113	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR2	3.13e-05	3	113	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR2	3.13e-05	3	113	2	7635066
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	HSPG2 NDUFS7 ADAM15 ENPP3 MCM7 PFKL PFKM FLG2 IGF1R ALPP	3.28e-05	613	113	10	22268729
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARHGEF28 GNB1L MAGI3 SHANK3 AP2M1 ARID2 FBXO42 DIP2C NEURL4	3.48e-05	493	113	9	15368895
Pubmed	Proximity Labeling Reveals Spatial Regulation of the Anaphase-Promoting Complex/Cyclosome by a Microtubule Adaptor.	SHKBP1 KCTD3 PLEKHA5	4.92e-05	22	113	3	35952650
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRAS1 HDAC5 ZFYVE16 DOCK9 TENM2 EPG5 ITSN2 MTMR3	5.76e-05	407	113	8	12693553
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNC	6.25e-05	4	113	2	11739414
Pubmed	A genome wide association study of plasma uric acid levels in obese cases and never-overweight controls.	FRAS1 DIP2C	6.25e-05	4	113	2	23703922
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNC	6.25e-05	4	113	2	22802962
Pubmed	Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.	RYR1 RYR2	6.25e-05	4	113	2	23992453
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR2	6.25e-05	4	113	2	23413940
Pubmed	An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice.	IGF1R PLEKHA5	6.25e-05	4	113	2	23518924
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR2	6.25e-05	4	113	2	9607712
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	RYR1 RYR2	6.25e-05	4	113	2	19120137
Pubmed	FKBP binding characteristics of cardiac microsomes from diverse vertebrates.	RYR1 RYR2	6.25e-05	4	113	2	11237759
Pubmed	Insulin and IGF1 receptors are essential for the development and steroidogenic function of adult Leydig cells.	IGF1R PLEKHA5	6.25e-05	4	113	2	29401624
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR2	6.25e-05	4	113	2	23482488
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR2	6.25e-05	4	113	2	18206662
Pubmed	Argonaute, Dicer, and Drosha are up-regulated along tumor progression in serous ovarian carcinoma.	DICER1 AGO1	6.25e-05	4	113	2	22647351
Pubmed	Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.	RYR1 RYR2	6.25e-05	4	113	2	22504960
Pubmed	The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actinin.	FLNA FLNC	6.25e-05	4	113	2	20554076
Pubmed	Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.	RYR1 IGF1R	6.25e-05	4	113	2	23695157
Pubmed	Stat6 signaling suppresses VLA-4 expression by CD8+ T cells and limits their ability to infiltrate tumor lesions in vivo.	ITGA4 STAT6	6.25e-05	4	113	2	18566374
Pubmed	A novel zinc finger protein, zic, is involved in neurogenesis, especially in the cell lineage of cerebellar granule cells.	RYR1 ZIC1	6.25e-05	4	113	2	7931345
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR2	6.25e-05	4	113	2	9384575
Pubmed	S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex.	RYR1 RYR2	6.25e-05	4	113	2	27226555
Pubmed	A SPRY1 domain cardiac ryanodine receptor variant associated with short-coupled torsade de pointes.	SPRY1 RYR2	6.25e-05	4	113	2	33664309
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNA FLNC NDUFS7 VPS45 NCKIPSD RPS13 KIAA1549 PFKL PFKM SHANK3 AP2M1 AGO1 ITSN2 PLEKHA5 BSN	6.27e-05	1431	113	15	37142655
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	FLNA VPS45 DDX60 UBR4 ISL2 MCM7 RDH13 PFKL PFKM DICER1 NPM3 AP2M1 TRAFD1 HEATR3 ALPP	6.73e-05	1440	113	15	30833792
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNA FLNC MACC1 UBR4 MAGI3 TKTL1 FNBP1L PFKM SRCAP RYR2 AP2M1 ITSN2 PABPC1L BSN PCDHGC3	6.83e-05	1442	113	15	35575683
Interaction	NXPH2 interactions	FRAS1 ADGRV1 SEZ6L2 FAT1 NXPH2	9.29e-07	33	110	5	int:NXPH2
Interaction	FBLIM1 interactions	FLNA FLNC PNPO SHKBP1 KCTD3	8.50e-06	51	110	5	int:FBLIM1
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	5.22e-05	3	76	2	287
GeneFamily	Blood group antigens\|CD molecules\|Proteoglycans	HSPG2 TGFBR3	3.61e-04	7	76	2	570
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	HSPG2 LRFN3 IGFBPL1 SIGLEC1 LRIT1	5.84e-04	161	76	5	593
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 FRAS1 ARHGEF28 FNBP1L FAT1 IGF1R DIP2C PLEKHA5	3.59e-08	194	113	8	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA CD248 RYR2 TGFBR3 FAT1 KCNT2 PZP	4.55e-08	200	113	8	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte\|Control_saline / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA CD248 TENM2 RYR2 FAT1 KCNT2 PZP	4.55e-08	200	113	8	cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA CD248 TENM2 TGFBR3 FAT1 KCNT2 PZP	4.55e-08	200	113	8	77631c471cc5d453a749784f838cfa6408caf09b
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF704 SPRY1 TENM2 RYR2 FAT1 KCNT2 PZP	5.88e-07	191	113	7	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MACC1 FRAS1 MAGI3 FNBP1L ADGRV1 FAT1 IGF1R	7.49e-07	198	113	7	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA CD248 TENM2 FAT1 KCNT2 PZP	8.01e-07	200	113	7	b22cae282591d8dead9869c2adbb9632615f50f7
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA RYR2 TGFBR3 FAT1 KCNT2 PZP	8.01e-07	200	113	7	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA RYR2 TGFBR3 FAT1 KCNT2 PZP	8.01e-07	200	113	7	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	IIH-CD4-CD8_1\|IIH / Condition, Cell_class and T cell subcluster	ADGRV1 PNPO NELL2 ARID2 FAM149B1 SARDH	1.92e-06	145	113	6	296b6b0eea3233d76742ea35252b2f54d4c27ab6
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSG2 ENPP3 KCTD3 SARDH SERPINF2 PZP	2.53e-06	152	113	6	c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DSG2 INSRR MAGI3 ADCY1 LOXHD1 NXPH2	5.88e-06	176	113	6	25ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNA FLNC ISL2 TGFBR3 KCNT2 GLRB	5.88e-06	176	113	6	a8875b4ba4abf6625cdeb67bf544ce1573c59060
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4\|TCGA-Thryoid / Sample_Type by Project: Shred V9	MACC1 DSG2 DOCK9 WDR55 GLRB PLEKHA5	7.58e-06	184	113	6	d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPRY1 CD248 ITGA4 RYR2 FAT1 KCNT2	7.58e-06	184	113	6	327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCell	COVID-19-Endothelial_cells-Systemic_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	HSPG2 SPRY1 DOCK9 FNBP1L SHANK3 TGFBR3	7.82e-06	185	113	6	f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCell	10x5'-Lung-Mast\|Lung / Manually curated celltypes from each tissue	ZNF704 HSPG2 ENPP3 KIAA1549 FAT1 DIP2C	8.31e-06	187	113	6	f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCell	10x5'-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	ZNF704 HSPG2 ENPP3 KIAA1549 FAT1 DIP2C	8.31e-06	187	113	6	da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 KIAA1549 FAT1 IGF1R DIP2C PLEKHA5	8.31e-06	187	113	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACC1 FRAS1 ARHGEF28 MAGI3 UNC13D ADGRV1	8.31e-06	187	113	6	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 ARHGEF28 ADAM15 DOCK9 SHANK3 LOXHD1	8.31e-06	187	113	6	25efb82afe863a853ecdd781ad89026c993aaa67
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI3 RYR2 TGFBR3 ARID2 ARNT2 CNOT2	8.57e-06	188	113	6	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI3 RYR2 TGFBR3 ARID2 ARNT2 CNOT2	8.57e-06	188	113	6	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAGI3 RYR2 TGFBR3 ARID2 ARNT2 CNOT2	8.57e-06	188	113	6	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 DSG2 MAGI3 FNBP1L ARNT2 NXPH2	8.57e-06	188	113	6	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF704 RYR2 TGFBR3 FAT1 KCNT2 PZP	8.83e-06	189	113	6	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	COVID-19_Severe-HSPC\|COVID-19_Severe / disease group, cell group and cell class	ZNF704 HSPG2 SPRY1 DSG2 SHANK3 PLEKHA5	8.83e-06	189	113	6	96015439971e2e5b8d6294ca5a6b873c7774e925
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ZNF704 FRAS1 ARHGEF28 MAGI3 ARID2 PLEKHA5	9.66e-06	192	113	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNA RYR2 TGFBR3 FAT1 KCNT2 PZP	9.66e-06	192	113	6	992d08092edbc68c47b945deb8708379738c239a
ToppCell	facs-Marrow-KLS-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF704 WEE1 KIAA1549 MCM7 PFKL PFKM	9.66e-06	192	113	6	03dcd9405d3d76fc7455066ba5d83c09cd17072d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ARHGEF28 FAT1 IGF1R DIP2C PLEKHA5	9.95e-06	193	113	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ZNF704 FRAS1 ARHGEF28 MAGI3 ARID2 PLEKHA5	9.95e-06	193	113	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	3'_v3-Lung-Mast\|Lung / Manually curated celltypes from each tissue	ZNF704 HSPG2 ENPP3 KIAA1549 FAT1 DIP2C	1.02e-05	194	113	6	5e6eb81ddc9d5e22c1297734689f476d5a05bff6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 FRAS1 ARHGEF28 FNBP1L FAT1 PLEKHA5	1.02e-05	194	113	6	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	3'_v3-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	ZNF704 HSPG2 ENPP3 KIAA1549 FAT1 DIP2C	1.02e-05	194	113	6	7b7f1714c4a9d9519c4d0e460cb87f2eb82392dd
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MAGI3 BRINP1 TENM2 RYR2 NELL2 PLEKHA5	1.06e-05	195	113	6	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Biopsy_IPF-Epithelial-AT1\|Biopsy_IPF / Sample group, Lineage and Cell type	CPA6 HSPG2 MAGI3 UNC13D KCNT2 ALPP	1.15e-05	198	113	6	75bdecbe111fededf6082b11de18b84ca308ef6d
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	DOCK9 RDH13 FLG2 TGFBR3 FBXO42 SIGLEC1	1.18e-05	199	113	6	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	cellseq2-Endothelial\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HSPG2 SPRY1 ADAM15 DOCK9 SHANK3 TGFBR3	1.22e-05	200	113	6	81bdf7a1ddc3e82b96526449e662cca26d7297b1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA CD248 TENM2 FAT1 KCNT2	1.22e-05	200	113	6	b5b5a32925f225610fe25a021a742d6397162863
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	FLNA TENM2 RYR2 FAT1 KCNT2 PZP	1.22e-05	200	113	6	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA TGFBR3 FAT1 KCNT2 PZP	1.22e-05	200	113	6	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPRY1 CD248 RYR2 FAT1 KCNT2 PZP	1.22e-05	200	113	6	4e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPRY1 CD248 ITGA4 FAT1 KCNT2 PZP	1.22e-05	200	113	6	cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCell	cellseq2-Endothelial-Endothelial_Vascular\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HSPG2 SPRY1 ADAM15 DOCK9 SHANK3 TGFBR3	1.22e-05	200	113	6	dc244a5ccec1b793dc4371fb2cd2c3fd4226283e
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	SPRY1 CD248 TENM2 RYR2 FAT1 KCNT2	1.22e-05	200	113	6	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	SPRY1 CD248 ITGA4 RYR2 FAT1 KCNT2	1.22e-05	200	113	6	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_3\|Control_saline / Treatment groups by lineage, cell group, cell type	SPRY1 FLNA TENM2 RYR2 FAT1 KCNT2	1.22e-05	200	113	6	b0866b497aa71d06cef25f9a335fa584e95fa7e0
ToppCell	cellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	HSPG2 SPRY1 ADAM15 DOCK9 SHANK3 TGFBR3	1.22e-05	200	113	6	0afc7a0f87eac48f772759c3b626758089733361
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	SPRY1 CD248 RYR2 FAT1 KCNT2 PZP	1.22e-05	200	113	6	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Col27a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MACC1 DDX60 NPM3 LOXHD1	1.44e-05	58	113	4	ee9038695d11a428dc222962721bfdf11dd6954f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Meis2-Meis2_Adamts19\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ENPP3 ISL2 IGFBPL1 ZIC1	2.88e-05	69	113	4	130b1a56afe6aee01cde56cb983cbc2c41861bb4
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Meis2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ENPP3 ISL2 IGFBPL1 ZIC1	2.88e-05	69	113	4	6568fcefcc0dca211f2acf6e4066f795489e758d
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RYR1 NELL2 ARID2 DIP2C PLEKHA5	3.56e-05	146	113	5	1bf67a9416f52198931b912a31be4bab09fefd19
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SPRY1 RYR1 NELL2 ARID2 SARDH	4.31e-05	152	113	5	b8aa62e3cf2b4c252db4bccfa75d881c4fa0a788
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	CDSN TENM2 ADCY1 RYR2 KCNT2	5.34e-05	159	113	5	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 GTF2A1L GLRB NEURL4 LRIT1	5.34e-05	159	113	5	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 GTF2A1L GLRB NEURL4 LRIT1	5.34e-05	159	113	5	7619d0d49738dd08daf01b42664691a5323aa793
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBR4 POLR3C SIGLEC1 SERPINF2 NEURL4	5.84e-05	162	113	5	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	severe-unassigned\|severe / disease stage, cell group and cell class	SRCAP PLEKHA5 PABPC1L FAM149B1 NEURL4	6.37e-05	165	113	5	f9ddd547992fec065d539a1d0305acba8fc7d79c
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZNF704 ENPP3 KIAA1549 DIP2C PZP	6.37e-05	165	113	5	37615622c736e43260c38016e7c9e565ac97a3e8
ToppCell	nucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZNF704 ENPP3 KIAA1549 DIP2C PZP	6.37e-05	165	113	5	640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCell	nucseq-Immune-Hematopoietic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZNF704 ENPP3 KIAA1549 DIP2C PZP	6.37e-05	165	113	5	f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRAS1 ARHGEF28 FAT1 KCNT2 ARNT2	6.93e-05	168	113	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	NS-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DSG2 ADAM15 KIAA1549 SEZ6L2 IGFBPL1	7.33e-05	170	113	5	f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D231\|Adult / Lineage, Cell type, age group and donor	ZNF704 FRAS1 MAGI3 ADGRV1 FAT1	7.33e-05	170	113	5	269dee5abca9f6aa079f116f0d8f1d198604d9d4
ToppCell	Control-Myeloid-Mast\|Control / Disease state, Lineage and Cell class	ZNF704 ENPP3 KIAA1549 DIP2C PZP	7.33e-05	170	113	5	9a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCell	Control-Myeloid-Mast\|World / Disease state, Lineage and Cell class	ZNF704 ENPP3 KIAA1549 DIP2C PZP	7.54e-05	171	113	5	ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 ADAM15 DOCK9 TENM2 SHANK3	7.54e-05	171	113	5	b3e6e31dfe3623b960ccf692fdbd236fa4039923
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HSPG2 ADAM15 DOCK9 SHANK3 ARNT2	7.54e-05	171	113	5	1597459c971d6befa991d59dc66b41b6a522f797
ToppCell	3'_v3-blood-Mast\|blood / Manually curated celltypes from each tissue	ZNF704 CDSN ENPP3 KIAA1549 FNBP1L	7.75e-05	172	113	5	e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DSG2 INSRR MAGI3 DIP2C NXPH2	8.40e-05	175	113	5	1d8da48236549c01381f777ce5b2937f9f86acc2
ToppCell	ICU-SEP-Myeloid-cDC2\|ICU-SEP / Disease, Lineage and Cell Type	MRPL19 KHDC1 KCTD3 PLEKHA5 SERPINF2	8.40e-05	175	113	5	c44fd1cc827296de7300d4a60399bb945089a170
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY1 RYR2 ZIC1 PLEKHA5 SIGLEC1	8.40e-05	175	113	5	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 RYR2 FCRL1 KCNT2	8.40e-05	175	113	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	Control-Myeloid-Mast\|Myeloid / Disease state, Lineage and Cell class	ZNF704 ENPP3 KIAA1549 DIP2C PZP	8.63e-05	176	113	5	0c5916d63e1ada09105e46d2429b75129b7329ec
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	MAGI3 ADGRV1 FAT1 RPIA ARNT2	8.63e-05	176	113	5	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	COVID-19-lung-MAST\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ENPP3 KIAA1549 ITGA4 DIP2C PZP	8.63e-05	176	113	5	473c45a381ca109207d66ed1635668b391ea0e1f
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 UNC13D LOXHD1 KCNT2 ALPP	9.35e-05	179	113	5	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	severe-Others-CD34+_GATA2+_cells\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HSPG2 SPRY1 DSG2 SHANK3 PLEKHA5	9.35e-05	179	113	5	dd789a1b7327d6f9ed5272f3eb54bd43f7ae8d78
ToppCell	3'_v3-bone_marrow-Mast\|bone_marrow / Manually curated celltypes from each tissue	ZNF704 HSPG2 CDSN ENPP3 KIAA1549	9.60e-05	180	113	5	b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCell	3'_v3-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	ZNF704 HSPG2 CDSN ENPP3 KIAA1549	9.85e-05	181	113	5	30ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 FAT1 KCNT2 DHRSX NXPH2	9.85e-05	181	113	5	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	critical-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ZNF704 HSPG2 ENPP3 KIAA1549 DIP2C	9.85e-05	181	113	5	f0d81ae74d3f32979624a94b2ef93774831a7970
ToppCell	COVID-19-kidney-CD-IC-B\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ARHGEF28 INSRR MAGI3 ADCY1 NXPH2	1.01e-04	182	113	5	ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell	COPD-Myeloid-Mast\|World / Disease state, Lineage and Cell class	ZNF704 ENPP3 KIAA1549 DIP2C PZP	1.01e-04	182	113	5	68a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MACC1 FRAS1 ARHGEF28 KIAA1549 FAT1	1.04e-04	183	113	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	FNBP1L SEZ6L2 TENM2 IGFBPL1	1.05e-04	96	113	4	56e993d37b7958abe56682422536045550e29b41
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 RYR2 FAT1 LOXHD1	1.06e-04	184	113	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HSPG2 MACC1 FRAS1 MAGI3 UNC13D	1.06e-04	184	113	5	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	IPF-Myeloid-Mast\|Myeloid / Disease state, Lineage and Cell class	ZNF704 ENPP3 KIAA1549 DIP2C PZP	1.06e-04	184	113	5	7326a16d7d3ae41b8c9d2beaec7f977b374f3469
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	HSPG2 ADAM15 DOCK9 ADCY1 SHANK3	1.06e-04	184	113	5	a809b0fa52df8a159f60f87eefcef61220af5e34
ToppCell	IPF-Myeloid-Mast\|World / Disease state, Lineage and Cell class	ZNF704 ENPP3 KIAA1549 DIP2C PZP	1.06e-04	184	113	5	7aefa182acad5a53c730945fec85329d7168606a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 RYR2 FAT1 LOXHD1	1.06e-04	184	113	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Posterior_cortex-Neuronal-Excitatory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	HAPLN4 BRINP1 TENM2 RYR2 NELL2	1.06e-04	184	113	5	25ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 ADGRV1 RYR2 FAT1 LOXHD1	1.06e-04	184	113	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	IPF-Myeloid-Mast\|IPF / Disease state, Lineage and Cell class	ZNF704 ENPP3 KIAA1549 DIP2C PZP	1.06e-04	184	113	5	c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNC CD248 ENPP3 INSRR GLRB	1.09e-04	185	113	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACC1 ARHGEF28 MAGI3 ADGRV1 NELL2	1.09e-04	185	113	5	0d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZNF704 SPRY1 TGFBR3 FAT1 PZP	1.09e-04	185	113	5	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
Drug	AC1Q6S7C	GTF2A1L TKTL1 PFKL PFKM RPIA	1.27e-06	39	111	5	CID000000616
Disease	Leber congenital amaurosis (implicated_via_orthology)	RDH14 RDH13 DHRSX	1.40e-05	13	110	3	DOID:14791 (implicated_via_orthology)
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	4.12e-05	3	110	2	DOID:3529 (implicated_via_orthology)
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNC	4.12e-05	3	110	2	DOID:0080096 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	4.12e-05	3	110	2	DOID:8545 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNC	4.12e-05	3	110	2	DOID:0111190 (implicated_via_orthology)
Disease	glycogen storage disease (implicated_via_orthology)	PFKL PFKM	8.22e-05	4	110	2	DOID:2747 (implicated_via_orthology)
Disease	uric acid measurement	FRAS1 VPS45 INSRR RDH14 FNBP1L ADGRV1 TENM2 IGF1R TRAFD1 DIP2C	9.74e-05	610	110	10	EFO_0004761
Disease	peeling skin syndrome (is_implicated_in)	CDSN FLG2	2.05e-04	6	110	2	DOID:0060283 (is_implicated_in)
Disease	emphysema imaging measurement	WEE1 BRINP1 FNBP1L FAM135B NXPH2	2.23e-04	146	110	5	EFO_0007626
Disease	alcohol dependence (implicated_via_orthology)	INSRR IGF1R	4.87e-04	9	110	2	DOID:0050741 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	FLNA GNB1L UBR4 HAPLN4 MRPL19 EPG5 IGF1R KCNT2 ITSN2 MTMR3 NFYC DIP2C	6.75e-04	1074	110	12	C0006142
Disease	sleep disorder (implicated_via_orthology)	INSRR IGF1R	7.41e-04	11	110	2	DOID:535 (implicated_via_orthology)
Disease	craniosynostosis (is_implicated_in)	FLNA ZIC1	8.87e-04	12	110	2	DOID:2340 (is_implicated_in)
Disease	diabetic neuropathy (implicated_via_orthology)	INSRR IGF1R	1.22e-03	14	110	2	DOID:9743 (implicated_via_orthology)
Disease	response to paliperidone, schizophrenia symptom severity measurement	ARHGEF28 VPS45 KIAA1549 TENM2 EPG5	1.32e-03	216	110	5	EFO_0007925, EFO_0007927
Disease	Generalized hypotonia	AP2M1 AGO1	1.40e-03	15	110	2	C1858120
Disease	Global developmental delay	PNPO AP2M1 IGF1R AGO1	1.57e-03	133	110	4	C0557874
Disease	Spondyloepiphyseal Dysplasia	HSPG2 FLNA	1.60e-03	16	110	2	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 FLNA	1.60e-03	16	110	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 FLNA	1.60e-03	16	110	2	C4551479
Disease	Schwartz-Jampel Syndrome	HSPG2 FLNA	1.60e-03	16	110	2	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 FLNA	1.60e-03	16	110	2	C0025237
Disease	Van Buchem disease	HSPG2 FLNA	1.81e-03	17	110	2	C0432272
Disease	left ventricular mass	SEZ6L2 IGF1R	2.03e-03	18	110	2	EFO_0009289
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 FLNA	2.26e-03	19	110	2	DOID:2256 (is_implicated_in)
Disease	Osteochondrodysplasias	HSPG2 FLNA	2.26e-03	19	110	2	C0029422
Disease	Dyschondroplasias	HSPG2 FLNA	2.26e-03	19	110	2	C0013366
Disease	Multiple Epiphyseal Dysplasia	HSPG2 FLNA	2.50e-03	20	110	2	C0026760
Disease	Testicular Germ Cell Tumor	TKTL1 DMRT1 HEATR3	2.59e-03	73	110	3	EFO_1000566
Disease	disease of metabolism (implicated_via_orthology)	PFKL PFKM	2.76e-03	21	110	2	DOID:0014667 (implicated_via_orthology)
Disease	cortical thickness	HSPG2 DOCK9 RDH14 FNBP1L ADGRV1 TENM2 NELL2 IGF1R FBXO42 KCTD3 MTMR3	2.97e-03	1113	110	11	EFO_0004840
Disease	pulmonary hypertension (biomarker_via_orthology)	HDAC5 RYR1 RYR2	3.36e-03	80	110	3	DOID:6432 (biomarker_via_orthology)
Disease	nephrotic syndrome (implicated_via_orthology)	FAT1 ITSN2	3.60e-03	24	110	2	DOID:1184 (implicated_via_orthology)
Disease	Cancer of Head	STAT6 FAT1	3.60e-03	24	110	2	C0751177
Disease	Head Neoplasms	STAT6 FAT1	3.60e-03	24	110	2	C0018675
Disease	Upper Aerodigestive Tract Neoplasms	STAT6 FAT1	3.60e-03	24	110	2	C0887900

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDSGVPQGVTQQVTH	EPG5	1091	Q9HCE0
RGISEQSLVVSGVQH	SERPINF2	366	P08697
GRISVQPSHQEPAGT	BRINP1	16	O60477
QPDGTRVVSEGHTLE	ADAM15	101	Q13444
TRVAGTQTTTHLPGI	CD248	536	Q9HCU0
GNIPAGTTVDTNITH	AGO1	726	Q9UL18
EITVVRNGGTHGNVS	ADGRV1	416	Q8WXG9
ENHVGPIINVTRTGG	ADGRV1	2131	Q8WXG9
VQGVHTVAQTVSRIP	ARID2	671	Q68CP9
GVLSTHQNIRAVVTG	ACSF3	211	Q4G176
PSSHSVSGGQRPVVV	CDSN	241	Q15517
VSGGQRPVVVVVDQH	CDSN	246	Q15517
GGPRVTINTAIGHIN	DICER1	621	Q9UPY3
VSEGTVTDVHIPQNG	CPA6	76	Q8N4T0
VVHVPGVNDIQSSSS	ARNT2	541	Q9HBZ2
GTLVGNVVHSRIISP	NXPH2	41	O95156
VQTESGGRIQHPFTV	PZP	206	P20742
NVHISPNGSIITIVG	HSPG2	3066	P98160
PGIVQSGGVVRIAHV	HSPG2	3531	P98160
GSVSPIHGQGQVVEN	ITSN2	886	Q9NZM3
RPVGGTTGSQIQHLT	KIAA1549	1811	Q9HCM3
QSSVPGHGLQETVTV	ARHGEF28	56	Q8N1W1
VVTERVIQPHGGGSN	DSG2	986	Q14126
TQVHVTVIGGNLHSP	FAT1	2476	Q14517
HPRGGQSQIVIDDAT	FBXO42	281	Q6P3S6
SQQRQPGSTVHGRLE	FLG2	2281	Q5D862
HVGTPLRSNIVTIGT	FRAS1	3281	Q86XX4
RGTHELTNPGIAEVT	GNB1L	246	Q9BYB4
VVASHRVATPQVSGE	MAGED4	131	Q96JG8
PDTAVISVVGSRHNQ	MAGI3	1001	Q5TCQ9
INGEPTQGITHTRAI	MAGI3	1071	Q5TCQ9
STTGVRQVPGLHNGT	NELL2	41	Q99435
SGSGPVRITGRHQIV	NPM3	126	O75607
GVVRSDQVIITDHPG	CD300H	76	A0A0K2S4Q6
SPLSRVSVGHGNVGV	LOXHD1	356	Q8IVV2
SSGGRVIPDVRVTQH	BSN	1331	Q9UPA5
PNHVTLGTIGVNRSQ	DDX60	1606	Q8IY21
HVVRLLGVVSQGQPT	IGF1R	1061	P08069
TRVTVLGHVQRGGTP	PFKL	291	P17858
TRVTVLGHVQRGGTP	PFKM	291	P08237
TATGGNHVTARVLNP	FLNC	1281	Q14315
PRSVHNVTGAQVGLS	IGFBPL1	161	Q8WX77
QQIGERGIHFSIVSP	MED25	171	Q71SY5
VNGTGTPVHISTLQV	GLRB	386	P48167
PTDRGVQVTEHGATA	LRFN3	426	Q9BTN0
SPQGQVLSAHVSGRV	AP2M1	186	Q96CW1
LVHTSRGQEGQQSPE	KCNT2	461	Q6UVM3
QIGAVVSHQSSVIPD	PNPO	166	Q9NVS9
IGLHTGQISTARPVQ	PCDHGC3	621	Q9UN70
PHTQRVANIGTQTTG	PABPC1L	476	Q4VXU2
VVEVSGTPNQLETHR	NFYC	386	Q13952
NGRPLNGTVHQEVSS	LRIT1	291	Q9P2V4
NTRIAQPGDHVSVTG	MCM7	261	P33993
SGVTVNALHPGVART	RDH13	221	Q8NBN7
GVVTTTRVQHASPAG	ALPP	166	P05187
STGVQGRIQVTEEVH	ADCY1	1011	Q08828
AGIHSSNVGVRVNVV	HEATR3	546	Q7Z4Q2
GRVVTSEQHIPVSAN	DOCK9	766	Q9BZ29
INHLVTQGRESPEGS	FNBP1L	491	Q5T0N5
HATERNGVNVVSGPI	ENPP3	736	O14638
VPTGARSNHLTSGVI	FCRL1	296	Q96LA6
SRVRVHGPGIQSGTT	FLNA	1356	P21333
EHSIQVERPQGSTGS	DIP2C	216	Q9Y2E4
SHVTANVVDPGVVNT	DHRSX	231	Q8N5I4
QGGSVQLPESDITVH	MACC1	221	Q6ZN28
RSQHTTEVVGGAPQH	ITGA4	261	P13612
HVVRLLGVVSQGQPT	INSRR	1041	P14616
ATGQTRVTVVGPHRA	KHDC1	136	Q4VXA5
SVVVQTAPGQVVSHR	HAPLN4	46	Q86UW8
TAPGQVVSHRGGTIV	HAPLN4	51	Q86UW8
SGISEVEGLSQHQVP	FAM135B	921	Q49AJ0
HGQSPLVTGERVATS	HDAC5	466	Q9UQL6
SPGQQGRISHTDLVI	RYR1	1501	P21817
TVPSGEHGEEQRRTV	RYR2	246	Q92736
GTSSGAVRVIVQHPE	KCTD3	391	Q9Y597
AVRVIVQHPETVGSG	KCTD3	396	Q9Y597
GSIEIGVTTHNPNSL	NEURL4	376	Q96JN8
QDIPAVTSRGHVENT	DMRT1	186	Q9Y5R6
ERPQVGSVVHRTSLG	MTMR3	891	Q13615
GTAEVEHVSTVGPQR	FAM149B1	476	Q96BN6
VAGSPIRHENAVQGS	ISL2	276	Q96A47
GIGSGSTIVHAVQRI	RPIA	101	P49247
SQNGAIAPGHVSVIR	TRAFD1	501	O14545
TSSGGVRVIVQHPET	SHKBP1	401	Q8TBC3
HEGRLTNVTRPTGVV	TENM2	1706	Q9NT68
DHGTVQPGETIQSQI	TGM4	636	P49221
EGTNVTVNVLHPGIV	RDH14	236	Q9HBH5
GTIHNATLGRIVSPE	SEZ6L2	351	Q6UXD5
GARAETQGANHTPVI	SRCAP	2401	Q6ZRS2
VGPAVQARGVHQSVA	NDUFS7	21	O75251
VPRRGTHTTVSQVQP	NCKIPSD	246	Q9NZQ3
RVAGVETQHGSIQTP	SARDH	251	Q9UL12
NHSQVGQGIGIPSRT	CNOT2	141	Q9NZN8
VHAGPVRQQSTGPSE	MRPL19	36	P49406
GGTRAQSVTQLGSHV	TRAV8-4	16	P01737
SPGESGTIVVTLNNH	SENP5	176	Q96HI0
IGDLGHVTRISSPQV	WEE1	461	P30291
TGQGNTEVIHTGTLQ	ZNF320	61	A2RRD8
TGSQPLRVIAHDTGT	POLR3C	31	Q9BUI4
VVHATSNGQEPSRLG	SHANK3	1211	Q9BYB0
VTETSGRAGILQHPI	GTF2A1L	141	Q9UNN4
ITIAHVIRGQDGSPQ	STAT6	571	P42226
TPSQIGVILRDSHGV	RPS13	46	P62277
PLEQRGTHAVVGVAT	SPSB2	96	Q99619
QHGSGSSLVVIQQPS	SPRY1	6	O43609
PGVRIVLGGTTVHNT	VPS45	526	Q9NRW7
EVQNVHGSERSGPVS	SIGLEC1	391	Q9BZZ2
HGSERSGPVSVVVNH	SIGLEC1	396	Q9BZZ2
GPNTIHRVGTVAEAV	PRSS48	296	Q7RTY5
PVGTGEQRQHAHTVL	ZNF704	351	Q6ZNC4
IGQEQVSPGDRVRSH	ZNF264	171	O43296
VTVEHVGGPEQSNHI	ZIC1	256	Q15915
ILPNRVVGSVGQHTG	WDR55	281	Q9H6Y2
IHTGRNPTIVTDVGR	ZNF543	556	Q08ER8
PVTGEAVVTGHRRQS	PLEKHA5	41	Q9HAU0
IQHPGTQVLIGTDSI	UBR4	4731	Q5T4S7
RVQDHTTVVGDVVSP	UNC13D	536	Q70J99
IQVHSLAVSGVPQSG	TKTL1	556	P51854
HTGETAGRQQVPTSP	TGFBR3	811	Q03167
TVVESQEGLSGTHVP	ZFYVE16	476	Q7Z3T8