Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B HSPA8

1.56e-0561863GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B HSPA8

1.56e-0561863GO:0055131
GeneOntologyMolecularFunctionprotein transporter activity

PEX1 TOMM20 SEC61A1 SEC61A2 LRP2

4.27e-05421865GO:0140318
GeneOntologyMolecularFunctionprotein domain specific binding

NCOA6 CFTR PTPN11 ADRB1 AFAP1L2 MYPN HSPA1A HSPA1B HSPA2 HSPA8 USP47 LAMP1 MED1 PIAS2 TFDP2 ARHGAP1 MTOR GUSB LRP2 CARD11

2.00e-0487518620GO:0019904
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

2.57e-0431862GO:0031249
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

HSPA1A HSPA1B HSPA8

3.33e-04151863GO:0140776
GeneOntologyMolecularFunctionlactoperoxidase activity

PXDN PXDNL

5.11e-0441862GO:0140825
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSPA1A HSPA1B HSPA2 HSPA8

5.13e-04401864GO:0140662
GeneOntologyBiologicalProcessintracellular transport

SMG1 VPS13C TM9SF4 PEX1 MPDZ TOMM20 EHD4 PIK3R4 BMP4 PTPN11 NF1 DST AP1G1 HSBP1 LRRC7 SEC61A1 HSPA1A HSPA1B HSPA8 VPS50 LAMP1 ICE1 SYBU MED1 ARHGAP1 SEC61A2 LRPPRC SYNE3 CSE1L LRP2 DOP1A XPO7

5.20e-06149618832GO:0046907
GeneOntologyBiologicalProcesscellular response to heat

NF1 HSBP1 HSPA1A HSPA1B HSPA8 RASA3 MTOR

9.20e-06811887GO:0034605
GeneOntologyBiologicalProcesscellular heat acclimation

HSBP1 HSPA1A HSPA1B

1.46e-0561883GO:0070370
GeneOntologyBiologicalProcessresponse to heat

NF1 HSBP1 HSPA1A HSPA1B HSPA2 HSPA8 RASA3 MTOR

1.53e-051211888GO:0009408
GeneOntologyBiologicalProcessheat acclimation

HSBP1 HSPA1A HSPA1B

2.54e-0571883GO:0010286
GeneOntologyBiologicalProcessregulation of inclusion body assembly

HSPA1A HSPA1B HSPA2 CDC34

3.54e-05211884GO:0090083
DomainARM-type_fold

SMG1 ARMH1 TRIP12 PIK3R4 NF1 AP1G1 BRAT1 GCN1 UNC79 UBR4 ARFGEF2 FRYL PPP4R4 CSE1L MTOR XPO7

2.25e-0733918216IPR016024
DomainARM-like

SMG1 ARMH1 TRIP12 PIK3R4 NF1 AP1G1 BRAT1 GCN1 ARFGEF2 FRYL PPP4R4 CSE1L MTOR XPO7

4.29e-0727018214IPR011989
Domain-

ARMH1 TRIP12 PIK3R4 NF1 AP1G1 BRAT1 GCN1 ARFGEF2 FRYL PPP4R4 CSE1L MTOR

1.91e-06222182121.25.10.10
DomainHSP70

HSPA1A HSPA1B HSPA2 HSPA8

1.45e-05161824PF00012
DomainHSP70_2

HSPA1A HSPA1B HSPA2 HSPA8

1.88e-05171824PS00329
DomainHSP70_1

HSPA1A HSPA1B HSPA2 HSPA8

1.88e-05171824PS00297
DomainHSP70_3

HSPA1A HSPA1B HSPA2 HSPA8

1.88e-05171824PS01036
DomainHsp_70_fam

HSPA1A HSPA1B HSPA2 HSPA8

2.40e-05181824IPR013126
DomainLRR_8

LRRC37A2 LGR4 SLIT2 LRRC37A PXDN PXDNL LRRC7 CPN2 TLR1

4.67e-051711829PF13855
DomainLRR_TYP

LRRC37A2 LGR4 SLIT2 LRRC37A PXDN PXDNL LRRC7 CPN2 TLR1

6.11e-051771829SM00369
DomainLeu-rich_rpt_typical-subtyp

LRRC37A2 LGR4 SLIT2 LRRC37A PXDN PXDNL LRRC7 CPN2 TLR1

6.11e-051771829IPR003591
DomainHEAT_REPEAT

SMG1 PIK3R4 BRAT1 GCN1 PPP4R4 MTOR

6.16e-05701826PS50077
DomainSecY_su_dom

SEC61A1 SEC61A2

9.44e-0521822IPR023201
DomainSECY_1

SEC61A1 SEC61A2

9.44e-0521822PS00755
DomainSECY_2

SEC61A1 SEC61A2

9.44e-0521822PS00756
Domain-

SEC61A1 SEC61A2

9.44e-05218221.10.3370.10
DomainTranslocon_Sec61/SecY_plug_dom

SEC61A1 SEC61A2

9.44e-0521822IPR019561
DomainSecY_CS

SEC61A1 SEC61A2

9.44e-0521822IPR030659
DomainPlug_translocon

SEC61A1 SEC61A2

9.44e-0521822PF10559
DomainSecY

SEC61A1 SEC61A2

9.44e-0521822PF00344
DomainSecY/SEC61-alpha

SEC61A1 SEC61A2

9.44e-0521822IPR002208
DomainLRR

LRRC37A2 LGR4 SLIT2 LRRC37A PXDN PXDNL LRRC7 CPN2 TLR1

1.61e-042011829PS51450
Domain-

HSPA1A HSPA2 HSPA8

1.88e-041218232.60.34.10
DomainHSP70_peptide-bd

HSPA1A HSPA2 HSPA8

1.88e-04121823IPR029047
Domain-

HSPA1A HSPA2 HSPA8

2.42e-041318231.20.1270.10
DomainHeat_shock_70_CS

HSPA1A HSPA2 HSPA8

2.42e-04131823IPR018181
DomainHSP70_C

HSPA1A HSPA2 HSPA8

2.42e-04131823IPR029048
DomainLRR_1

LRRC37A2 LGR4 SLIT2 LRRC37A PXDN PXDNL LRRC7 CPN2 TLR1

3.05e-042191829PF00560
DomainGPS

ADGRG5 ADGRG4 ADGRF5 ADGRG6

3.22e-04341824SM00303
DomainGPS

ADGRG5 ADGRG4 ADGRF5 ADGRG6

3.61e-04351824PF01825
DomainGPS

ADGRG5 ADGRG4 ADGRF5 ADGRG6

4.03e-04361824PS50221
DomainGPS

ADGRG5 ADGRG4 ADGRF5 ADGRG6

4.48e-04371824IPR000203
DomainPPR

DENND4A LRPPRC

5.59e-0441822PF01535
DomainLRRC37AB_C

LRRC37A2 LRRC37A

5.59e-0441822IPR029423
DomainLRRC37AB_C

LRRC37A2 LRRC37A

5.59e-0441822PF14914
DomainLRRC37_N

LRRC37A2 LRRC37A

5.59e-0441822IPR032754
DomainLRRC37

LRRC37A2 LRRC37A

5.59e-0441822PF15779
DomainLRRC37A/B-like

LRRC37A2 LRRC37A

5.59e-0441822IPR015753
DomainHEAT_type_2

PIK3R4 GCN1 PPP4R4

5.60e-04171823IPR021133
DomainGPCR_2_extracellular_dom

ADGRG5 ADGRG4 ADGRF5 ADGRG6

6.06e-04401824IPR001879
DomainG_PROTEIN_RECEP_F2_1

ADGRG5 ADGRG4 ADGRF5 ADGRG6

6.06e-04401824PS00649
DomainG_PROTEIN_RECEP_F2_3

ADGRG5 ADGRG4 ADGRF5 ADGRG6

6.06e-04401824PS50227
DomainGlyco_trans_29

ST6GAL2 ST8SIA6 ST3GAL4

9.18e-04201823IPR001675
DomainGlyco_transf_29

ST6GAL2 ST8SIA6 ST3GAL4

9.18e-04201823PF00777
DomainProtocadherin

PCDH11X PCDH11Y

9.26e-0451822PF08374
DomainFATC

SMG1 MTOR

9.26e-0451822PF02260
DomainProtocadherin

PCDH11X PCDH11Y

9.26e-0451822IPR013585
DomainEPHD

KMT2A MLLT10 RAI1

1.22e-03221823PS51805
DomainPEROXIDASE_1

PXDN PXDNL

1.38e-0361822PS00435
DomainFAT

SMG1 MTOR

1.38e-0361822PS51189
DomainFATC

SMG1 MTOR

1.38e-0361822PS51190
DomainFATC_dom

SMG1 MTOR

1.38e-0361822IPR003152
DomainPIK_FAT

SMG1 MTOR

1.38e-0361822IPR014009
DomainFATC

SMG1 MTOR

1.38e-0361822SM01343
DomainLeu-rich_rpt

LRRC37A2 LGR4 SLIT2 LRRC37A PXDN PXDNL LRRC7 CPN2 TLR1

1.39e-032711829IPR001611
Domain7tm_2

ADGRG5 ADGRG4 ADGRF5 ADGRG6

1.42e-03501824PF00002
DomainG_PROTEIN_RECEP_F2_2

ADGRG5 ADGRG4 ADGRF5 ADGRG6

1.42e-03501824PS00650
DomainCys-rich_flank_reg_C

SLIT2 PXDN PXDNL CPN2 TLR1

1.87e-03901825IPR000483
DomainLRRCT

SLIT2 PXDN PXDNL CPN2 TLR1

1.87e-03901825SM00082
DomainDAGAT

AWAT1 DGAT2

1.92e-0371822PF03982
DomainDAGAT

AWAT1 DGAT2

1.92e-0371822IPR007130
DomainIGc2

DCC PXDN PXDNL MYPN ADGRF5 VCAM1 SIGLEC6 IGSF1

2.19e-032351828SM00408
DomainIg_sub2

DCC PXDN PXDNL MYPN ADGRF5 VCAM1 SIGLEC6 IGSF1

2.19e-032351828IPR003598
DomainFN3

DCC COL6A3 COL12A1 TIE1 ASTN1 ROS1 ANKFN1

2.28e-031851827SM00060
DomainHEAT

PIK3R4 BRAT1 GCN1 MTOR

2.46e-03581824IPR000357
DomainPPR

DENND4A LRPPRC

2.54e-0381822PS51375
DomainIg_I-set

DCC PXDN PXDNL MYPN ADGRF5 VCAM1 SIGLEC6

2.65e-031901827IPR013098
DomainI-set

DCC PXDN PXDNL MYPN ADGRF5 VCAM1 SIGLEC6

2.65e-031901827PF07679
DomainLRRNT

LGR4 SLIT2 PXDN PXDNL CPN2

2.72e-03981825IPR000372
DomainLRRNT

LGR4 SLIT2 PXDN PXDNL CPN2

2.72e-03981825SM00013
DomainGPCR_2_secretin-like

ADGRG5 ADGRG4 ADGRF5 ADGRG6

2.78e-03601824IPR000832
DomainGPCR_2-like

ADGRG5 ADGRG4 ADGRF5 ADGRG6

2.78e-03601824IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRG5 ADGRG4 ADGRF5 ADGRG6

2.95e-03611824PS50261
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSBP1 HSPA1A HSPA1B HSPA2 HSPA8 MTOR

6.09e-08231356MM14953
PathwayREACTOME_ATTENUATION_PHASE

HSBP1 HSPA1A HSPA1B HSPA2 HSPA8

9.05e-08131355MM14952
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSBP1 HSPA1A HSPA1B HSPA2 HSPA8 MTOR

1.48e-06381356M27255
PathwayREACTOME_ATTENUATION_PHASE

HSBP1 HSPA1A HSPA1B HSPA2 HSPA8

6.16e-06281355M27254
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TOPAZ1 VPS13C CSMD2 TRIP12 CHRNB4 FANCA OR2K2 AFAP1L2 DST MYO3B CPSF1 LRRC7 HSPA8 PCLO UBR4 ICE1 ST3GAL4 LRP2 HADHA RPE65 RAI1

1.08e-097361932129676528
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

UTP14A TRIP12 NF1 DST CPSF1 KMT2A GCN1 HSPA2 USP47 UBR4 FRYL LRPPRC CSE1L MTOR HADHA CTNNA1 SPEN RAI1 XPO7

5.13e-096531931922586326
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 DENND4A LIN54 UTP14A TOMM20 DCC F2RL1 TRIP12 EHD4 DST PXDN DGAT2 KMT2A SEC61A1 HSPA2 HSPA8 PCLO UBR4 PALB2 LETM1 PPP4R4 SEC61A2 LRPPRC KIAA0825 HADHA SPEN RAI1 DOP1A

8.64e-0914421932835575683
Pubmed

Defining the membrane proteome of NK cells.

EHD4 PIK3R4 NF1 AP1G1 BRAT1 GCN1 HSPA2 HSPA8 NIBAN1 UBR4 VPS50 ARFGEF2 LAMP1 ST3GAL4 MED1 NBAS LRPPRC PIGT SYNE3 CSE1L DCP1B MTOR GUSB LPCAT3 PRR11

8.88e-0911681932519946888
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ABCC3 NCOA6 LAMC3 FANCA BMP4 DST CPSF1 BRAT1 GCN1 EP400 RASA3 UBR4 ARFGEF2 FRYL ICE1 MLLT10 CDC14B PLCD3 SYNE3 MTOR SPEN ULK2 RAI1

6.07e-0811051932335748872
Pubmed

Function and regulation of heat shock factor 2 during mouse embryogenesis.

HSPA1A HSPA1B HSPA2 HSPA8

6.32e-08819349122205
Pubmed

Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.

HSPA1A HSPA1B HSPA2 HSPA8

1.13e-079193421763498
Pubmed

Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis.

HSPA1A HSPA1B HSPA8

1.68e-073193323352621
Pubmed

Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes.

HSPA1A HSPA1B HSPA8

1.68e-073193315129916
Pubmed

Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study.

HSPA1A HSPA1B HSPA2

1.68e-073193321373891
Pubmed

HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease.

HSPA1A HSPA2 HSPA8

1.68e-073193336246562
Pubmed

Functional analysis of HSPA1A and HSPA8 in parturition.

HSPA1A HSPA1B HSPA8

1.68e-073193328025138
Pubmed

Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.

HSPA1A HSPA1B HSPA2 HSPA8

1.88e-0710193411932435
Pubmed

gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.

HSPA1A HSPA1B HSPA2 HSPA8

1.88e-0710193412832005
Pubmed

Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.

HSPA1A HSPA1B HSPA2 HSPA8

1.88e-071019347906708
Pubmed

Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.

HSPA1A HSPA1B HSPA2 HSPA8

1.88e-0710193423921388
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

TM9SF4 TRIP12 PXDN GCN1 ARFGEF2 FRYL ICE1 MED1 NBAS MTOR

2.17e-072021931033005030
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NCOA6 ZNF326 DENND4A UBAP2 MPDZ TRIP12 PIK3R4 FSIP2 NF1 DST KMT2A CCSER1 FRYL PPP4R4 LRPPRC DCP1B MTOR GEN1 DOP1A

3.85e-078611931936931259
Pubmed

HIV-1 viral protein R (Vpr) and its interactions with host cell.

HSPA1A HSPA1B HSPA2 HSPA8

4.39e-0712193419275587
Pubmed

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

HSPA1A HSPA1B HSPA2 HSPA8

6.32e-0713193427477512
Pubmed

Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.

HSPA1A HSPA1B HSPA8

6.70e-074193318299791
Pubmed

Upregulation of the constitutively expressed HSC70 by KLF4.

HSPA1A HSPA1B HSPA8

6.70e-074193318379898
Pubmed

Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations.

HSPA1A HSPA1B HSPA2

6.70e-074193318813331
Pubmed

Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.

HSPA1A HSPA1B HSPA8

6.70e-074193322956628
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

DST AP1G1 KMT2A HSPA1B GCN1 HSPA2 UNC79 HSPA8 PCLO UBR4 IQCN ARHGAP1 NBAS LRPPRC CSE1L HADHA CTNNA1 HYDIN

6.78e-078071931830575818
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

ZNF326 TRIP12 HSBP1 BRAT1 HSPA1A HSPA8 UBR4 VPS50 ARFGEF2 MTOR CTNNA1

7.11e-072881931123383273
Pubmed

Absence of layer-specific cadherin expression profiles in the neocortex of the reeler mutant mouse.

RELN PCDH11X PCDH11Y PCDH8

8.81e-0714193420847152
Pubmed

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.

HSPA1A HSPA1B HSPA2 HSPA8

1.20e-0615193410964507
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ZNF326 DENND4A VPS13C UTP14A LAMC3 EHD4 FANCD2 PIK3R4 PTPN11 NF1 AP1G1 CPSF1 SEC61A1 HSPA1A GCN1 HSPA8 PCLO UBR4 LETM1 LRPPRC CSE1L MTOR HADHA SPEN

1.40e-0614251932430948266
Pubmed

Clathrin facilitates the morphogenesis of retrovirus particles.

HSPA1A HSPA1B HSPA2 HSPA8

1.59e-0616193421738476
Pubmed

A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.

HSPA1A HSPA1B HSPA8

1.67e-065193311584023
Pubmed

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

HSPA1A HSPA1B HSPA8

1.67e-065193316906134
Pubmed

HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.

HSPA1A HSPA1B HSPA8

1.67e-065193317182002
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

VPS13C UTP14A PEX1 ARMCX4 EHD4 FANCD2 DST CPSF1 SEC61A1 USP47 BMP2K PCLO UBR4 SYBU LETM1 ARHGAP1 SEC61A2 NBAS LRPPRC DNAAF10 LRP2 HADHA PRR11 GEN1

3.24e-0614961932432877691
Pubmed

Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.

HSPA1A HSPA1B HSPA8

3.32e-066193315963462
Pubmed

RING finger protein RNF207, a novel regulator of cardiac excitation.

HSPA1A HSPA1B HSPA8

3.32e-066193325281747
Pubmed

Genetic aspects of the hsp70 multigene family in vertebrates.

HSPA1A HSPA1B HSPA8

3.32e-06619337988674
Pubmed

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

HSPA1A HSPA1B HSPA8

3.32e-06619339305631
Pubmed

Heat shock factor 2 is activated during mouse heart development.

HSPA1A HSPA1B HSPA8

3.32e-066193311032181
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

SEC61A1 HSPA1A GCN1 HSPA8 LRPPRC CSE1L HADHA CTNNA1 DHRS2

4.11e-06219193931353912
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

LIN54 DST HSPA1A HSPA1B GCN1 LCORL UBR4 ZNF507 ICE1 PIAS2 PALB2 LRP2

4.33e-064181931234709266
Pubmed

Interaction network of human early embryonic transcription factors.

NCOA6 LIN54 KMT2A EP400 PIAS2 DNAAF10 ASXL3 CTNNA1 SPEN PRDM6 RAI1

4.79e-063511931138297188
Pubmed

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway.

HSPA1A HSPA1B HSPA8

5.79e-067193310205060
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PEX1 TRIP12 FANCA FANCD2 SLIT2 PXDN AP1G1 BRAT1 SEC61A1 GCN1 HSPA2 UBR4 LRPPRC CSE1L MTOR HADHA CTNNA1 XPO7

5.89e-069421931831073040
Pubmed

Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.

TOMM20 DCC HSPA8 LAMP1

6.22e-0622193427407143
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

HSPA1A HSPA1B HSPA2 HSPA8

7.49e-0623193421231916
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCOA6 TRIP12 FANCD2 NF1 CPSF1 KMT2A HSPA8 USP47 EP400 ZNF507 ARFGEF2 IQCN MED1 PALB2 CTNNA1 SPEN

7.54e-067741931615302935
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

CPSF1 HSPA1A HSPA1B GCN1 HSPA2 HSPA8 LRPPRC HADHA CDC34

7.78e-06237193929564676
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ZNF326 VPS13C LIN54 UTP14A LGR4 TRIP12 CDKL5 DST GCN1 EP400 BMP2K ARFGEF2 ARHGAP1 PRR11 SPEN XPO7

7.91e-067771931635844135
Pubmed

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription.

HSPA1A HSPA1B HSPA2 HSPA8

8.95e-0624193410617616
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

AP1G1 SEC61A1 GCN1 HSPA2 HSPA8 CSE1L MTOR XPO7

9.08e-06183193823956138
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SMG1 NCOA6 UBAP2 VPS13C TOMM20 ST6GAL2 DST EP400 VPS50 ZNF507 ICE1 IGSF1 RAI1

9.18e-065291931314621295
Pubmed

Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.

ADGRG5 ADGRG4 ADGRF5

9.23e-068193312435584
Pubmed

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy.

HSPA1A HSPA1B HSPA2

9.23e-068193322495301
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TM9SF4 GCN1 PCLO UBR4 FRYL ASTN1

9.39e-0687193612465718
Pubmed

Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.

DCC FANCA ST6GAL2 DST PXDN PXDNL IQCN TLR1 LRP2 GEN1

1.10e-053131931020800603
Pubmed

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.

HSPA1A HSPA1B HSPA2 HSPA8 LRPPRC

1.27e-0554193531792442
Pubmed

Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78.

HSPA1A HSPA1B HSPA2

1.38e-05919338486356
Pubmed

Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.

CFTR TRIP12 SEC61A1 HSPA1A HSPA2 HSPA8 SEC61A2 CSE1L

1.44e-05195193817110338
Pubmed

Loss of Cubilin, the intrinsic factor-vitamin B12 receptor, impairs visceral endoderm endocytosis and endodermal patterning in the mouse.

BMP4 AP1G1 LAMP1 LRP2

1.46e-0527193431308417
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 ABCC3 NCOA6 CSMD2 NF1 USP47 UBR4 MED1 PIAS2 PPP4R4 PIGT ASXL3 SPEN RAI1

1.48e-056381931431182584
Pubmed

USP7 controls NGN3 stability and pancreatic endocrine lineage development.

HSPA1A HSPA1B GCN1 HSPA8 LRPPRC

1.80e-0558193537117185
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SMG1 DENND4A UTP14A PEX1 MPDZ FANCA PIK3R4 DST AP1G1 CARD6 KMT2A SEC61A1 LETM1 PLCD3

1.81e-056501931438777146
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRG5 ADGRG4 ADGRF5 ADGRG6

1.96e-0529193415203201
Pubmed

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.

HSPA1B HSPA2 HSPA8

1.96e-0510193319171884
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

ZNF326 UTP14A TRIP12 EHD4 PIK3R4 NF1 DST AP1G1 A2ML1 CPSF1 GCN1 HSPA8 EP400 RASA3 UBR4 PLCD3 LRPPRC CSE1L HADHA DHRS2 PRR11

2.27e-0513531932129467282
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

TOPAZ1 GC TRIP12 PIK3R4 CPSF1 KMT2A VPS50 PCDHB6 KIAA0825 CTNNA1 HYDIN RAI1

2.42e-054971931236774506
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

ZNF326 UTP14A SHC3 DST PXDN CPSF1 SEC61A1 HSPA1A HSPA1B HSPA2 HSPA8 BMP2K PLCD3 LRPPRC CSE1L HADHA CTNNA1

2.45e-059491931736574265
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

MPDZ TRIP12 PIK3R4 DST SEC61A1 USP47 UBR4 LRPPRC

2.63e-05212193833853758
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

UBAP2 TM9SF4 LIN54 EHD4 UBE2R2 PTPN11 AP1G1 A2ML1 SEC61A1 HSPA1A GCN1 HSPA8 UBR4 LAMP1 FRYL ARHGAP1 LRPPRC MTOR HADHA CTNNA1 XPO7

2.63e-0513671932132687490
Pubmed

delta-Protocadherins: a gene family expressed differentially in the mouse brain.

PCDH11X PCDH11Y PCDH8

2.69e-0511193315905963
Pubmed

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.

HSPA1A HSPA1B HSPA8

2.69e-0511193327708256
Pubmed

Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.

HSPA1A HSPA1B HSPA8

2.69e-0511193324318877
Pubmed

SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria.

TOMM20 HSPA1A HSPA1B

2.69e-0511193323885119
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DENND4A VPS13C PEX1 TOMM20 PIK3R4 DST ARFGEF2 NBAS PIGT LPCAT3 LRP2 PRR11

2.78e-055041931234432599
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

VPS13C SEC61A1 HSPA1B HSPA2 HSPA8 VPS50 ARFGEF2

2.82e-05156193730409884
Pubmed

Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.

HSPA1A HSPA1B

3.06e-052193212411538
Pubmed

In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.

HSPA1A HSPA1B

3.06e-05219323786141
Pubmed

Processing of U14 small nucleolar RNA from three different introns of the mouse 70-kDa-cognate-heat-shock-protein pre-messenger RNA.

HSPA1B HSPA8

3.06e-05219327813466
Pubmed

Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.

HSPA1A HSPA1B

3.06e-052193226923070
Pubmed

Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.

HSPA1A HSPA1B

3.06e-052193226976620
Pubmed

Pcdh11x Negatively Regulates Dendritic Branching.

PCDH11X PCDH11Y

3.06e-052193225687328
Pubmed

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

HSPA1A HSPA1B

3.06e-052193220235222
Pubmed

Genetic determinants of HSP70 gene expression following heat shock.

HSPA1A HSPA1B

3.06e-052193220876613
Pubmed

The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.

HSPA1A HSPA1B

3.06e-052193220223214
Pubmed

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.

HSPA1A HSPA1B

3.06e-052193220093776
Pubmed

Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.

HSPA1A HSPA1B

3.06e-052193223704948
Pubmed

Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.

HSPA1A HSPA1B

3.06e-052193217513788
Pubmed

IL-6 activates HSP72 gene expression in human skeletal muscle.

HSPA1A HSPA1B

3.06e-052193212207910
Pubmed

Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals.

HSPA1A HSPA1B

3.06e-052193229572464
Pubmed

HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.

HSPA1A HSPA1B

3.06e-052193212714332
Pubmed

Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.

HSPA1A HSPA1B

3.06e-052193219299581
Pubmed

Differential acquisition of antigenic peptides by Hsp70 and Hsc70 under oxidative conditions.

HSPA1B HSPA8

3.06e-052193212114509
Pubmed

Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.

PCDH11X PCDH11Y

3.06e-052193222592879
Pubmed

Siglec-6 Signaling Uses Src Kinase Tyrosine Phosphorylation and SHP-2 Recruitment.

PTPN11 SIGLEC6

3.06e-052193236359823
Pubmed

hsp72, a host determinant of measles virus neurovirulence.

HSPA1A HSPA1B

3.06e-052193216971451
Pubmed

Involvement of serine protease and proteinase-activated receptor 2 in dermatophyte-associated itch in mice.

RELN F2RL1

3.06e-052193222761302
Pubmed

Role of Hsc70 binding cycle in CFTR folding and endoplasmic reticulum-associated degradation.

CFTR HSPA8

3.06e-052193221697503
Pubmed

Heat shock protein 70 promotes lipogenesis in HepG2 cells.

HSPA1A HSPA1B

3.06e-052193229631603
Pubmed

Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.

PCDH11X PCDH11Y

3.06e-052193221276771
InteractionOPALIN interactions

FANCD2 NF1 MYO3B GCN1 HSPA8 VPS50 ARFGEF2 PLCD3 SEC61A2 CSE1L MTOR XPO7

5.80e-0720918612int:OPALIN
InteractionGPR17 interactions

FANCA FANCD2 PIK3R4 BRAT1 VPS50 ARFGEF2 NBAS CSE1L MTOR LPCAT3 DOP1A XPO7

1.33e-0528318612int:GPR17
InteractionUSP19 interactions

CFTR SEC61A1 HSPA1A GCN1 HSPA8 SEC61A2 LRPPRC CSE1L DNAAF10

1.34e-051541869int:USP19
InteractionSIRT7 interactions

UTP14A TRIP12 UBE2R2 NF1 DST CPSF1 KMT2A GCN1 HSPA2 USP47 UBR4 FRYL LRPPRC CSE1L MTOR HADHA CTNNA1 SPEN RAI1 XPO7

1.90e-0574418620int:SIRT7
InteractionLRRC31 interactions

TM9SF4 TRIP12 PXDN GCN1 ARFGEF2 FRYL ICE1 MED1 NBAS MTOR

2.15e-0520518610int:LRRC31
InteractionRNF123 interactions

TOPAZ1 VPS13C CSMD2 TRIP12 CHRNB4 FANCA OR2K2 AFAP1L2 DST MYO3B CPSF1 LRRC7 HSPA8 PCLO UBR4 ICE1 ST3GAL4 LRP2 HADHA RPE65 RAI1

2.56e-0582418621int:RNF123
InteractionTPTE interactions

LGR4 FANCD2 SEC61A1 GCN1 UBR4 LRPPRC CSE1L HADHA

2.67e-051291868int:TPTE
InteractionZUP1 interactions

CFTR NF1 HSPA1A HSPA2 HSPA8 UBR4 FRYL CSE1L MTOR

3.54e-051741869int:ZUP1
InteractionGPR55 interactions

TM9SF4 FANCA FANCD2 PIK3R4 BRAT1 MTOR

3.57e-05671866int:GPR55
InteractionPROKR1 interactions

CFTR FANCD2 GCN1 XPO7

3.72e-05211864int:PROKR1
InteractionPDIA3 interactions

CFTR FANCD2 FSIP2 PTPN11 KMT2A SEC61A1 HSPA1A HSPA1B HSPA8 COL12A1 SYNE3 CSE1L MTOR HYDIN FILIP1L

3.76e-0547618615int:PDIA3
InteractionMFSD4A interactions

F2RL1 FANCA FANCD2 BRAT1 GCN1 ARFGEF2 SEC61A2 CSE1L MTOR XPO7

4.76e-0522518610int:MFSD4A
InteractionNPTN interactions

SMG1 FANCA FANCD2 BRAT1 GCN1 VPS50 ARFGEF2 CSE1L MTOR DOP1A XPO7

5.73e-0527818611int:NPTN
InteractionCTNNB1 interactions

ZNF326 CFTR UTP14A MPDZ FANCA FANCD2 CDKL5 SLIT2 UBE2R2 PTPN11 DST PTPRQ KMT2A HSPA1A HSPA1B HSPA8 EP400 ARFGEF2 LAMP1 MLLT10 LRPPRC ZBTB25 CTNNA1

5.88e-05100918623int:CTNNB1
InteractionASTN1 interactions

CDKL5 LAMP1 ASTN1

6.24e-0591863int:ASTN1
InteractionCDRT15P3 interactions

PEX1 HSPA2 HSPA8 UBR4

6.46e-05241864int:CDRT15P3
InteractionFPR1 interactions

FANCA FANCD2 BRAT1 GCN1 ARFGEF2 CSE1L MTOR XPO7

6.77e-051471868int:FPR1
InteractionNUP205 interactions

LGR4 TOMM20 FANCD2 HSPA1A HSPA8 VCAM1 LAMP1 ROS1 CDC34 XPO7

6.85e-0523518610int:NUP205
InteractionCDH5 interactions

SMG1 FANCD2 PTPN11 PTPRQ NBAS HADHA CTNNA1

6.87e-051091867int:CDH5
InteractionRAB7A interactions

DENND4A VPS13C PEX1 TOMM20 FANCD2 PIK3R4 DST HSPA1A HSPA2 HSPA8 ARFGEF2 LAMP1 LETM1 NBAS LRPPRC PIGT LPCAT3 LRP2 HADHA PRR11 CDC34

7.29e-0588618621int:RAB7A
InteractionYWHAH interactions

NCOA6 ZNF326 DENND4A UBAP2 CFTR MPDZ TRIP12 FANCD2 PIK3R4 UBE2R2 NF1 DST KMT2A HSPA1A CCSER1 LAMP1 FRYL MED1 PIAS2 PPP4R4 DCP1B MTOR GEN1 DOP1A

8.18e-05110218624int:YWHAH
InteractionGPR182 interactions

TM9SF4 F2RL1 FANCA FANCD2 PIK3R4 BRAT1 GCN1 VPS50 ARFGEF2 SEC61A2 CSE1L MTOR LPCAT3 XPO7

8.84e-0545518614int:GPR182
InteractionCCDC117 interactions

HSPA1A HSPA1B HSPA2 HSPA8

8.96e-05261864int:CCDC117
InteractionARHGAP18 interactions

AP1G1 HSPA1B HSPA2 HSPA8 BMP2K ARHGAP1 DCP1B

9.64e-051151867int:ARHGAP18
InteractionFTCD interactions

DST HSPA1A HSPA1B HSPA2

1.39e-04291864int:FTCD
InteractionFBXL15 interactions

HECW1 HSPA1B HSPA2 HSPA8

1.39e-04291864int:FBXL15
InteractionPML interactions

LIN54 TOMM20 ZNF280B FANCD2 PTPN11 NF1 AP1G1 KMT2A BRAT1 HSPA1A AIM2 GCN1 HSPA8 EP400 MED1 PIAS2 LRPPRC CSE1L MTOR ZBTB25 LPCAT3

1.50e-0493318621int:PML
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B HSPA2 HSPA8

5.15e-06171274583
GeneFamilyAdhesion G protein-coupled receptors, subfamily G

ADGRG5 ADGRG4 ADGRG6

1.16e-0571273917
GeneFamilyNon-clustered protocadherins

PCDH11X PCDH11Y PCDH8

7.11e-0512127321
GeneFamilyFibronectin type III domain containing

DCC PTPRQ COL12A1 TIE1 ASTN1 ROS1 ANKFN1

1.37e-041601277555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

DCC PXDN PXDNL MYPN ADGRF5 VCAM1 SIGLEC6

1.42e-041611277593
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

FANCA FANCD2 PALB2

3.54e-04201273548
GeneFamilySialyltransferases

ST6GAL2 ST8SIA6 ST3GAL4

3.54e-04201273438
GeneFamilyExportins

CSE1L XPO7

1.00e-0371272547
GeneFamilyDiacylglycerol O-acyltransferase 2 family

AWAT1 DGAT2

1.33e-03812721235
GeneFamilyATP binding cassette subfamily C

ABCC3 CFTR

3.63e-03131272807
CoexpressionGSE30083_SP2_VS_SP4_THYMOCYTE_DN

ADGRG5 F2RL1 ST8SIA6 SMPDL3A KMT2A AIM2 NIBAN1 RASA3 ZBTB25 TLR1

2.06e-0620018910M5035
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

ADAMTS19 DENND4A LGR4 HPSE2 SLIT2 PCDH11X AIM2 HSPA8 COL6A3 NIBAN1 COL12A1 RNF152 BMP2K RASA3 LCORL CDC14B TFDP2 PPP4R4 ASXL3 HADHA

5.06e-0674018020gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

ADAMTS19 PDK4 LGR4 PCDH11X CCNJL COL12A1 RNF152 RASA3 SERPINA6 PPP4R4 HADHA

2.03e-0527018011gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_1000
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN HECW1 CFTR DCC PTPRQ PCDH11X UNC79 COL12A1 PCLO ASXL3 LRP2 ROS1 HYDIN

1.47e-12184191132cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN HECW1 CFTR DCC PTPRQ PCDH11X UNC79 COL12A1 PCLO ASXL3 LRP2 ROS1 HYDIN

1.47e-1218419113ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN HECW1 CFTR DCC PTPRQ PCDH11X UNC79 COL12A1 PCLO ASXL3 LRP2 ROS1 HYDIN

1.47e-12184191132b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

ABCC3 PDK4 HPSE2 SLIT2 DST HSPA1A HSPA1B VCAM1 PCDH11Y ADGRG6 PRDM6

6.79e-101901911162a3ec1ae0829602b0569cc051210551644f1d46
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ST6GAL2 DST MYO3B CCSER1 ZDHHC14 IQCN ULK2 RAI1 ZNF44

6.82e-0918219110a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGSL1 HECW1 HPSE2 MYPN PTPRQ LRRC7 SERPINA6 ROS1 HYDIN

1.37e-08145191996712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 HPSE2 CSMD2 BMP4 PXDN COL6A3 PCDHB6 ADGRG6 PRDM6

7.31e-081761919852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 HPSE2 CSMD2 BMP4 PXDN COL6A3 PCDHB6 ADGRG6 PRDM6

7.31e-081761919d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDK4 HPSE2 DCC SLIT2 DST SMPDL3A COL6A3 ZDHHC14 PRDM6

1.34e-071891919203c80030df08ae112f9ae4043709f455d87ce89
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

MPDZ HPSE2 SLIT2 PXDN COL6A3 COL12A1 ADGRG6 ASXL3 PRDM6

2.08e-0719919195b9d355795dd03a22f0961dfd143425c367a4654
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

HECW1 DCC CSMD2 SHC3 AFAP1L2 PXDN PCDH11X CCSER1 PCDH11Y

2.17e-072001919f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

HECW1 DCC CSMD2 SHC3 AFAP1L2 PXDN PCDH11X CCSER1 PCDH11Y

2.17e-072001919cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

HECW1 DCC CSMD2 SHC3 AFAP1L2 PXDN PCDH11X CCSER1 PCDH11Y

2.17e-072001919c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

HECW1 DCC CSMD2 SHC3 AFAP1L2 PXDN PCDH11X CCSER1 PCDH11Y

2.17e-0720019194fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

HECW1 DCC CSMD2 SHC3 AFAP1L2 PXDN PCDH11X CCSER1 PCDH11Y

2.17e-072001919310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

HECW1 DCC CSMD2 SHC3 AFAP1L2 PXDN PCDH11X CCSER1 PCDH11Y

2.17e-072001919961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 CFTR DCC PTPRQ COL12A1 LRP2 ASTN1 HYDIN

4.68e-071601918c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 CFTR DCC PTPRQ COL12A1 LRP2 ASTN1 HYDIN

4.68e-07160191825c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellAdult-Mesenchymal-myofibroblast_cell-D175|Adult / Lineage, Cell type, age group and donor

UTP14A HPSE2 CSMD2 FSIP2 SLIT2 AFAP1L2 COL6A3 DNAAF10

4.91e-071611918048b7dc00746987a24bf870d4d278c4183eb04a2
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RGSL1 HECW1 HPSE2 MYPN PTPRQ LRRC7 ROS1 HYDIN

5.15e-071621918bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ABCC3 FSIP2 PXDN MYO3B COL12A1 ADGRG6 PLCD3 IGSF1

8.10e-0717219180be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

LGR4 F2RL1 PXDN COL6A3 CCDC110 PLCD4 ASTN1 PRDM6

8.46e-07173191875e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

LGR4 F2RL1 PXDN COL6A3 CCDC110 PLCD4 ASTN1 PRDM6

8.46e-07173191826e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A VPS13C FANCA PCLO FRYL MTOR GRAMD2B DOP1A

8.84e-071741918f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellNS-critical-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFTR LGR4 DST ST8SIA6 ADGRF5 RNF152 ADGRG6 SLC9A2

1.19e-061811918cfc3ed541d93158ce26641ea30b7573d93600a11
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMC3 AFAP1L2 PXDNL ADGRF5 HSPA2 COL6A3 RNF152 ADGRG6

1.52e-061871918fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 ST6GAL2 DST LRRC7 COL6A3 NIBAN1 PRDM6 FILIP1L

1.71e-0619019182e88e366d377d74deb53a4ea870973ce5c6532e8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 ST6GAL2 DST LRRC7 COL6A3 NIBAN1 PRDM6 FILIP1L

1.71e-0619019180028f886c789ba238c031eae5d96acaed4af8c25
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

CFTR SHC3 ADGRF5 CCSER1 CCNJL PCLO LRP2 ROS1

1.78e-061911918276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LGR4 LRRC7 TAF4B ARFGEF2 MED1 SEC61A2 SYNE3

1.85e-0613419179e12aac8f42790c2f104dfd61c87aa99fc7925f1
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HPSE2 BMP4 DST PXDN COL6A3 COL12A1 PRDM6 FILIP1L

1.92e-061931918084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LGR4 BMP4 LRRC7 COL6A3 RNF152 ADGRG6 IGSF1 PRDM6

1.92e-061931918e2b455387d1de7812305200a2041a0f4759a6f54
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HPSE2 DCC SLIT2 ST6GAL2 SMPDL3A VCAM1 COL6A3 ZDHHC14

2.00e-06194191899577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCC SLIT2 PXDNL LRRC7 VCAM1 COL6A3 ASXL3 PRDM6

2.00e-06194191889b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAMTS19 HPSE2 SLIT2 ST6GAL2 SMPDL3A VCAM1 COL6A3 ZDHHC14

2.08e-06195191870387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PDK4 HPSE2 SLIT2 DST VCAM1 COL6A3 ADGRG6 PRDM6

2.08e-0619519181cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ABCC3 SLIT2 DST SMPDL3A VCAM1 COL6A3 ASXL3 PRDM6

2.24e-0619719180034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDK4 HPSE2 SLIT2 PXDN VCAM1 COL6A3 COL12A1 FILIP1L

2.33e-0619819187582ee9ec8a87ecb094201f1f9191b412f9d2875
ToppCellILEUM-non-inflamed-(8)_Fibroblasts|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDK4 HPSE2 BMP4 DST VCAM1 COL6A3 COL12A1 FILIP1L

2.41e-061991918d9d7f36b4b5592b7855448730044c90997b55499
ToppCellILEUM-inflamed-(8)_Fibroblasts|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PDK4 HPSE2 BMP4 DST VCAM1 COL6A3 COL12A1 FILIP1L

2.41e-0619919183a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS19 HPSE2 PXDN MYO3B PCDH11X HSPA1A COL6A3 COL12A1

2.41e-061991918da016849b804fbf80edbfa8f8f56c9df8bbf2d51
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HECW1 CSMD2 ST6GAL2 AFAP1L2 LRRC7 UNC79 ASTN1 HYDIN

2.41e-06199191819a97e27a4758e794ce7246d295e112b47931a48
ToppCelldistal-mesenchymal-Myofibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ADAMTS19 HECW1 HPSE2 SLIT2 COL6A3 COL12A1 PRDM6 FILIP1L

2.51e-062001918069c8949b33ecfdb6da32992002d4060ff6082bc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 ST6GAL2 DST MYO3B CCSER1 ZDHHC14 IQCN

6.51e-061621917373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LGR4 HPSE2 PXDNL PCDH11Y PCDHB6 ADGRG6 PRDM6

7.06e-061641917e3983f655cdba308fb192182829f17bef99ce0ba
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN ARMCX4 ST6GAL2 DST BRAT1 SYNE3 DHRS2

7.95e-061671917b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN ARMCX4 ST6GAL2 DST BRAT1 SYNE3 DHRS2

7.95e-061671917fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN ARMCX4 ST6GAL2 DST BRAT1 SYNE3 DHRS2

7.95e-061671917f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

UBAP2 EHD4 CPSF1 TAF4B VCAM1 TIE1 DOP1A

7.95e-061671917774f3264318b002d0df5d06d41d645366038d0bf
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN ARMCX4 ST6GAL2 DST BRAT1 SYNE3 DHRS2

7.95e-06167191726cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFTR ARMCX4 PXDN ST8SIA6 SMPDL3A ADGRF5 SLC9A2

9.63e-06172191704fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFTR ARMCX4 PXDN ST8SIA6 SMPDL3A ADGRF5 SLC9A2

9.63e-061721917dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellT_cells-Tph_and_Tfh|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PTPN11 SMPDL3A HSPA1A AIM2 COL6A3 LPCAT3 GRAMD2B

1.12e-05176191756c055488e34605d32562571a2fee621b47c9441
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 F2RL1 AFAP1L2 DST VCAM1 FRYL ADGRG6

1.29e-05180191767c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFTR CSMD2 FSIP2 DST ADGRF5 RNF152 SLC9A2

1.34e-05181191740df0afcb6848202da54670e84f22d7c3a515d01
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARMCX4 AFAP1L2 DST ADGRF5 ADGRG6 TIE1 RRH

1.34e-0518119174d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RELN PDK4 HSPA1A RNF152 ZDHHC14 TIE1 FILIP1L

1.34e-051811917e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFTR CSMD2 FSIP2 DST ADGRF5 RNF152 SLC9A2

1.34e-0518119172b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFTR CSMD2 FSIP2 DST ADGRF5 RNF152 SLC9A2

1.34e-0518119176aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFTR CSMD2 FSIP2 DST ADGRF5 RNF152 SLC9A2

1.34e-05181191740d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 DGAT2 PTPRQ CCSER1 ADGRG6 CARD11 DHRS2

1.39e-051821917678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 DGAT2 PTPRQ CCSER1 ADGRG6 CARD11 DHRS2

1.39e-0518219178d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HPSE2 F2RL1 COL12A1 RASA3 CDC14B PRDM6 FILIP1L

1.39e-051821917ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFTR DST PXDN ST8SIA6 ADGRF5 RNF152 SLC9A2

1.44e-051831917ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCelldroplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL1 BMP4 AFAP1L2 VCAM1 ADGRG6 PLCD3 TIE1

1.55e-051851917eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCellILEUM-inflamed-(7)_Lymphatics|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN MPDZ CLEC4M ADGRF5 RNF152 PCLO TIE1

1.55e-051851917d711dd2e91cfee723dae1ccb2b910b8cf3becc3b
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CFTR ST8SIA6 ADGRF5 HSPA2 RNF152 CCDC110 SLC9A2

1.55e-051851917c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 AFAP1L2 DST ADGRF5 VCAM1 ADGRG6 TIE1

1.60e-0518619179c7924875f70420720149287c500b4dfa8d24673
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RELN PDK4 MPDZ RNF152 ZDHHC14 TIE1 FILIP1L

1.60e-05186191720340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 DST MYO3B CCSER1 ZDHHC14 SYBU ZNF44

1.66e-05187191787b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

HPSE2 SLIT2 DST COL6A3 COL12A1 RNF152 PRDM6

1.66e-051871917464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 DST MYO3B CCSER1 ZDHHC14 SYBU ZNF44

1.66e-05187191742a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 DST MYO3B CCSER1 ZDHHC14 SYBU ZNF44

1.66e-05187191764afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 BMP4 AFAP1L2 DST VCAM1 ADGRG6 TIE1

1.66e-05187191712129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARMCX4 BMP4 AFAP1L2 DST VCAM1 ADGRG6 TIE1

1.66e-05187191783930ef55191eff9006113feaeabb3c2fa21fd05
ToppCellPericytes-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

HECW1 LAMC3 HSPA2 COL6A3 COL12A1 RNF152 PLCD4

1.71e-051881917f16ff998393bf1954bbf10caab15173bdb104ac1
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

SMG1 DENND4A VPS13C NF1 AP1G1 KMT2A SPEN

1.71e-051881917ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

CFTR DCC ADGRF5 CCSER1 PCLO PPP4R4 ROS1

1.71e-051881917ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADGRG5 DCC TAF4B PARPBP HSPA1A SYNE3 GEN1

1.71e-051881917567b08514d9d84cbb40f9b7a679eec304f023428
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS19 BMP4 DST COL6A3 COL12A1 CCDC110 SYBU

1.77e-051891917473b01c9162b12b90a617c600238436177a0d18d
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

F2RL1 EHD4 AFAP1L2 ADGRF5 ADGRG6 PLCD3 TIE1

1.77e-0518919172e43428f1ef9683c6f8c9897d46aa7d34bf9047f
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

PDK4 PXDNL MYPN CCSER1 NIBAN1 CDC14B HADHA

1.83e-0519019173729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCC SLIT2 BMP4 PXDNL VCAM1 COL6A3 PRDM6

1.83e-051901917841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ABCC3 CFTR MYO3B CCSER1 NIBAN1 PPP4R4 LRP2

1.90e-05191191760ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

LAMC3 SLIT2 ADGRF5 COL6A3 NIBAN1 COL12A1 RNF152

1.90e-05191191778c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCC SLIT2 BMP4 PXDNL VCAM1 COL6A3 PRDM6

1.96e-0519219176f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HECW1 CSMD2 BMP4 VCAM1 COL6A3 COL12A1 PRDM6

1.96e-05192191767e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS19 CFTR ADGRG4 CLCN1 CCL25 CCSER1 ADGRG6

1.96e-051921917d6ea34391c3f730684b82e912d9cf55e928b3311
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LAMC3 AFAP1L2 PXDNL HSPA2 COL12A1 RNF152 ASTN1

1.96e-0519219175000440dc1ed17e7474d340921bdff945646f27e
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

ADAMTS19 SLIT2 LRRC7 COL6A3 COL12A1 ASTN1 PRDM6

1.96e-051921917a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

HECW1 HPSE2 SLIT2 DST COL6A3 COL12A1 PRDM6

2.03e-051931917e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN PCDH11X RNF152 PCDH11Y ADGRG6 SLC9A2 SYNE3

2.03e-0519319173ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN PCDH11X RNF152 PCDH11Y ADGRG6 SLC9A2 SYNE3

2.03e-051931917658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 PDK4 MYO3B CCSER1 SLC9A2 CARD11 ANKFN1

2.10e-05194191704bfc555743f7d8821439d05ae442d15e9886c59
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DCC F2RL1 PXDN VCAM1 UBR4 ADGRG6 LRP2

2.10e-05194191770185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS19 RELN DST PTPRQ VCAM1 ADGRG6 DHRS2

2.10e-05194191743eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 LAMC3 COL6A3 NIBAN1 COL12A1 PRDM6 FILIP1L

2.10e-051941917ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LGR4 LAMC3 PXDNL COL12A1 RNF152 IGSF1 RPE65

2.10e-05194191767f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HPSE2 LAMC3 SHC3 DST COL6A3 COL12A1 FILIP1L

2.17e-051951917d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFTR ADGRG4 CLCN1 CCL25 HSPA1A BMP2K ADGRG6

2.17e-051951917e87b11e3242fdbed2e7f383e6876ec375af32bd4
DiseaseLeukemia, Myelocytic, Acute

FANCA FANCD2 PTPN11 NF1 PXDN KMT2A MLLT10 PALB2 CTNNA1

1.58e-061731859C0023467
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B HSPA8

2.40e-0651853DOID:0081267 (biomarker_via_orthology)
DiseaseAcute monocytic leukemia

FANCA FANCD2 KMT2A PALB2

2.01e-05261854C0023465
Diseaseleukemia

FANCA FANCD2 PTPN11 NF1 KMT2A

2.48e-05551855C0023418
Diseasevital capacity

ADAMTS19 NCOA6 LGR4 DCC TRIP12 C3orf49 DST MYPN COL6A3 LCORL PCLO ARFGEF2 MLLT10 MED1 CDC14B ADGRG6 CSE1L GUSB LRP2 ANKFN1 FILIP1L

3.48e-05123618521EFO_0004312
DiseaseMalignant neoplasm of breast

ADAMTS19 NCOA6 LRRC37A2 PIK3R4 BMP4 NF1 LRRC37A CLCN1 LRRC7 HSPA1B UBR4 ARFGEF2 PALB2 SLC9A2 MTOR SPEN GEN1 PCDH8 DOP1A

4.92e-05107418519C0006142
DiseaseMYELODYSPLASTIC SYNDROME

FANCA FANCD2 PTPN11 PALB2 CTNNA1

6.47e-05671855C3463824
DiseaseFanconi anemia

FANCA FANCD2 PALB2

8.39e-05141853cv:C0015625
Diseasealcohol consumption measurement

RELN TOPAZ1 LAMC3 DCC ST6GAL2 NF1 AP1G1 MYH16 CCSER1 COL12A1 LCORL PCLO ZDHHC14 TMEM138 MED1 NBAS LRPPRC MTOR CTNNA1 XPO7

1.12e-04124218520EFO_0007878
DiseaseCAKUT (is_implicated_in)

BMP4 HSPA1B

1.17e-0431852DOID:0080205 (is_implicated_in)
DiseaseDiaphragmatic Hernia

CFTR BMP4 VCAM1 LRP2

1.26e-04411854C0019284
Diseasedual specificity mitogen-activated protein kinase kinase 2 measurement

LAMP1 SERPINA6 PPP4R4

1.28e-04161853EFO_0008112
DiseaseMyocardial Ischemia

PDK4 F2RL1 ADRB1 HSPA1A HSPA2 VCAM1 HADHA

1.28e-041761857C0151744
DiseaseAcute Myeloid Leukemia, M1

PTPN11 NF1 PXDN KMT2A MLLT10 CTNNA1

1.42e-041251856C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

PTPN11 NF1 PXDN KMT2A MLLT10 CTNNA1

1.42e-041251856C1879321
Diseasemelanoma

DCC F2RL1 NF1 HSPA1A UBR4 MLLT10 ROS1 RAI1

1.81e-042481858C0025202
DiseaseBone marrow hypocellularity

FANCA FANCD2 PALB2

1.85e-04181853C1855710
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

PALB2 MLH3 CTNNA1

2.18e-04191853C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

PALB2 MLH3 CTNNA1

2.18e-04191853C2936783
DiseaseJUVENILE MYELOMONOCYTIC LEUKEMIA

PTPN11 NF1

2.33e-0441852607785
DiseaseUllrich congenital muscular dystrophy

COL6A3 COL12A1

2.33e-0441852cv:C4551860
DiseaseBethlem myopathy

COL6A3 COL12A1

2.33e-0441852cv:C1834674
DiseaseBETHLEM MYOPATHY 1

COL6A3 COL12A1

2.33e-0441852C1834674
DiseaseUllrich congenital muscular dystrophy 1

COL6A3 COL12A1

2.33e-0441852C0410179
DiseaseBethlem myopathy (is_implicated_in)

COL6A3 COL12A1

2.33e-0441852DOID:0050663 (is_implicated_in)
DiseaseJuvenile myelomonocytic leukemia

PTPN11 NF1

2.33e-0441852cv:C0349639
DiseaseUllrich congenital muscular dystrophy (is_implicated_in)

COL6A3 COL12A1

2.33e-0441852DOID:0050558 (is_implicated_in)
Diseasecognitive inhibition measurement

PXDNL A2ML1 ADGRG6 CTNNA1

2.75e-04501854EFO_0007969
DiseaseNeurodevelopmental Disorders

TRIP12 CDKL5 PTPN11 KMT2A ASXL3

3.05e-04931855C1535926
Diseaseinterstitial cystitis (is_marker_for)

VCAM1 MTOR

3.86e-0451852DOID:13949 (is_marker_for)
Diseasejuvenile myelomonocytic leukemia (implicated_via_orthology)

PTPN11 NF1

3.86e-0451852DOID:0050458 (implicated_via_orthology)
DiseaseNoonan Syndrome

PTPN11 NF1 A2ML1

4.45e-04241853C0028326
DiseaseFanconi Anemia

FANCA FANCD2 PALB2

5.04e-04251853C0015625
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

PALB2 MLH3 CTNNA1

5.67e-04261853C0009405
DiseasePancytopenia

FANCA FANCD2 PALB2

5.67e-04261853C0030312
Diseaseunipolar depression, depressive symptom measurement

DCC KMT2A ARFGEF2

5.67e-04261853EFO_0003761, EFO_0007006
DiseaseEye Diseases, Hereditary

LRP2 RPE65

5.77e-0461852C0015398
DiseaseHereditary non-polyposis colorectal cancer syndrome

PALB2 MLH3 CTNNA1

6.35e-04271853C1112155
Diseaseazoospermia (implicated_via_orthology)

UBE2R2 NDST2 CDC34

6.35e-04271853DOID:14227 (implicated_via_orthology)
DiseaseCholestasis

ABCC3 CFTR DGAT2 VCAM1 NIBAN1

6.60e-041101855C0008370
Diseasechronic obstructive pulmonary disease (is_implicated_in)

CFTR GC F2RL1 ADRB1

6.68e-04631854DOID:3083 (is_implicated_in)
Diseasemonocyte count

DENND4A GC CLEC4M F2RL1 SHC3 EHD4 FANCA OR2K2 NF1 ADGRF5 VCAM1 BMP2K RASA3 ST3GAL4 IQCN MLLT10 TFDP2 GUSB RAI1

6.68e-04132018519EFO_0005091
DiseaseMiller Dieker syndrome

FANCA FANCD2 PALB2

7.86e-04291853C0265219
DiseaseHereditary Nonpolyposis Colorectal Cancer

PALB2 MLH3 CTNNA1

7.86e-04291853C1333990
Diseasegrapefruit juice consumption measurement

PCLO DCP1B

8.04e-0471852EFO_0010094
Diseasejuvenile myelomonocytic leukemia (is_implicated_in)

PTPN11 NF1

8.04e-0471852DOID:0050458 (is_implicated_in)
Diseasecongenital heart disease (implicated_via_orthology)

UBE2R2 KMT2A LRP2 CDC34

9.41e-04691854DOID:1682 (implicated_via_orthology)
Diseaseneuroticism measurement, cognitive function measurement

DCC LCORL PCLO ZNF507 TMEM138 SYBU MLLT10 CSE1L KIAA0825 ASXL3 RAI1

9.42e-0456618511EFO_0007660, EFO_0008354
Diseaselung volume

LCORL ADGRG6

1.07e-0381852EFO_0600046
DiseaseAttached earlobe

MYO3B ADGRG6

1.07e-0381852HP_0009907
DiseaseAbnormality of radial ray

FANCA FANCD2 PALB2

1.15e-03331853C4228778
Diseasegallbladder neoplasm

DCC KIAA0825

1.37e-0391852EFO_0004606
DiseaseMajor depression, single episode

HSPA1A HSPA1B

1.37e-0391852C0024517
Diseasealpha-1-antitrypsin measurement

SERPINA6 PPP4R4

1.37e-0391852EFO_0008327
Diseaseforced expiratory volume

NCOA6 DCC C3orf49 DST MYPN BMP2K LCORL ARFGEF2 MED1 ADGRG6 SLC9A2 CSE1L ANKFN1

1.49e-0378918513EFO_0004314
Diseasedilated cardiomyopathy (implicated_via_orthology)

NCOA6 PTPN11 ADRB1 MED1

1.63e-03801854DOID:12930 (implicated_via_orthology)
DiseaseColorectal Carcinoma

ABCC3 CFTR DCC CDKL5 BMP4 NF1 PCDH11X MLH3 CSE1L LRP2 DHRS2 GABRA6

1.67e-0370218512C0009402
DiseaseFanconi anemia (is_implicated_in)

FANCA FANCD2

1.70e-03101852DOID:13636 (is_implicated_in)
Diseaseacute myeloid leukemia (is_implicated_in)

FANCA NF1 KMT2A MLLT10

1.95e-03841854DOID:9119 (is_implicated_in)
Diseasebody height at birth

ADRB1 LCORL ADGRG6

2.02e-03401853EFO_0006784
DiseaseAutism Spectrum Disorders

RELN LAMC3 TRIP12 RAI1

2.04e-03851854C1510586
Diseaseinterleukin 1 receptor-like 1 measurement

ST3GAL4 SLC9A2

2.07e-03111852EFO_0008168
Diseasecampesterol measurement

CCSER1 ANKFN1

2.07e-03111852EFO_0020008
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

RELN TRIP12 FANCA UNC79 LCORL IQCN MLLT10 FILIP1L

2.19e-033641858EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseaseattention function measurement

LAMC3 CSMD2 CHRNB4 DST MYPN

2.46e-031481855EFO_0007636
Diseaseouter ear morphology trait

MYO3B ADGRG6

2.48e-03121852EFO_0007664
Diseasenasopharyngeal neoplasm

KMT2A PCLO ZNF507 MED1 PCDH8

2.69e-031511855EFO_0004252
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

DCC FANCA SPEN

2.84e-03451853DOID:3748 (is_implicated_in)
Diseaseresponse to radiation, hearing loss, response to antineoplastic agent

UBE2R2 LRRC7 TFDP2

3.02e-03461853EFO_0004238, GO_0009314, GO_0097327
DiseaseSalivary Gland Neoplasms

FANCA ST3GAL4 SPEN

3.21e-03471853C0036095
DiseaseMetabolic Bone Disorder

GC LRP2

3.39e-03141852C0005944
Diseaserespiratory quotient

TOMM20 DCC

3.39e-03141852EFO_0005189
Diseaselobe size

MYO3B ADGRG6

3.39e-03141852EFO_0007666
Diseasephoneme awareness

ARFGEF2 CSE1L

3.39e-03141852EFO_0021812
Diseaseinsulin metabolic clearance rate measurement, glucose homeostasis measurement

DCC ST8SIA6

3.39e-03141852EFO_0006830, EFO_0006896
DiseaseBirth Weight

ADRB1 LCORL

3.39e-03141852C0005612
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

ADRB1 NF1 ZNF507

3.61e-03491853EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
DiseaseGeneralized seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0234533
DiseaseClonic Seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0234535
DiseaseConvulsive Seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0751494
DiseaseSeizures, Sensory

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0751496
Diseaseneurotic disorder

DCC CCSER1 PCLO ASXL3

3.81e-031011854EFO_0004257
DiseaseNon-epileptic convulsion

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0751056
DiseaseAtonic Absence Seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0751123
DiseaseComplex partial seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0149958
DiseaseSingle Seizure

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0751110
DiseaseNonepileptic Seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C3495874
DiseaseVisual seizure

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0270824
DiseaseEpileptic drop attack

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0270846
DiseaseVertiginous seizure

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0422855
DiseaseGustatory seizure

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0422854
DiseaseSeizures, Somatosensory

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0422850
DiseaseOlfactory seizure

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0422853
DiseaseSeizures, Auditory

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0422852
DiseaseGeneralized Absence Seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C4505436
DiseaseJacksonian Seizure

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C0022333
DiseaseEpileptic Seizures

MPDZ CHRNB4 CDKL5 LETM1

3.81e-031011854C4317109
Diseasebody fat percentage

RELN TRIP12 FANCA UNC79 LCORL IQCN MLLT10 CSE1L FILIP1L

3.82e-034881859EFO_0007800
DiseaseOsteopenia

GC LRP2

3.89e-03151852C0029453
Diseaseinfant head circumference

ADRB1 ARFGEF2

3.89e-03151852EFO_0004577

Protein segments in the cluster

PeptideGeneStartEntry
SNSKPVVSNILNRVT

ZNF280B

51

Q86YH2
PATSSSQLISIKLQL

CHRNB4

46

P30926
VAIAKTPRLQTLTNL

ADRB1

81

P08588
ALKTQFLTTPISQAQ

EP400

3016

Q96L91
TPKVTQALNVLTTTF

BRAT1

211

Q6PJG6
NPISSSKRNVSLLIS

CCL25

131

O15444
LQDSLTKISLQQTPI

C9orf50

206

Q5SZB4
PLTSLQTLKLSNNAL

CPN2

191

P22792
TRKVSLAPQANLTEL

CFTR

791

P13569
SLPLATSNQVLIKFS

CSMD2

1696

Q7Z408
KSLTERIPLSNLQTI

ADGRG4

2611

Q8IZF6
KTNAIPLTVILQSSV

CDC14B

441

O60729
LVVQKTRLQISQDPS

GOT1L1

51

Q8NHS2
VSLRNQKVILPQTSD

ADGRG6

151

Q86SQ4
KINTLQTQPLGTIVN

AIM2

251

O14862
LQAKILSDPSVLQLT

ARMH1

276

Q6PIY5
TFTISQSVLVTNLKP

A2ML1

1416

A8K2U0
QLQIIKALLTAVTSP

ARFGEF2

136

Q9Y6D5
PSLRITTVKIQTEQQ

AFAP1L2

606

Q8N4X5
VPKLEQINSTRILSS

CCNJL

151

Q8IV13
ILKTNPIAFVNAIST

DOP1A

1391

Q5JWR5
FSKPVLQSQSISLVQ

CCSER1

191

Q9C0I3
TEVTIQNKILLQPTS

CCDC180

1621

Q9P1Z9
QNKILLQPTSSISTT

CCDC180

1626

Q9P1Z9
VLTIQSSATPVKVLA

BMP2K

386

Q9NSY1
IVQTLVNSVNSSIPK

BMP4

356

P12644
LIANAPTSLINIFSK

ARMCX4

2201

Q5H9R4
QVPDKQLTTISLIIR

ASTN1

1106

O14525
RETTTVLQQSLNPSK

ASXL3

1176

Q9C0F0
ILSNVISKSTRPNTL

DENND4A

1066

Q7Z401
SNTVQQLLLSKAAVP

RAI1

446

Q7Z5J4
PQTSRTLTLISKTVQ

RASA3

506

Q14644
KINVNTITSPRLAAL

ADAMTS19

1146

Q8TE59
ITKTPAQLRSVATIL

IQCN

501

Q9H0B3
LRTPTNAIIINLAVT

RRH

56

O14718
LTLFRSPTQVNNSIK

PARPBP

391

Q9NWS1
PQLISNLTQASVSLK

ABCC3

586

O15438
PTQLVNTSSVQLVKS

PDK4

76

Q16654
KTFQLQLLSPSSSIV

AP1G1

756

O43747
TVVTPKTLANLLTSN

OR8H2

76

Q8N162
TPQKNSNLLVIIVVT

DCC

1091

P43146
TPVTISANQIILNKV

LIN54

106

Q6MZP7
RLTAQAVSIVISKLP

KIAA0825

966

Q8IV33
ITRQLSTPQSQKQTL

LRRC37A2

166

A6NM11
ITRQLSTPQSQKQTL

LRRC37A

166

A6NMS7
LSNLPTTIASLVNLK

LRRC7

81

Q96NW7
TQIETKNPRVNLLVS

DST

7136

Q03001
GSLSPVNSQKITLLL

HECW1

936

Q76N89
VNSQKITLLLQSPAV

HECW1

941

Q76N89
ITLLLQSPAVKFITN

HECW1

946

Q76N89
KVTTNPNLRIISLNT

SMPDL3A

196

Q92484
QLKIPQLRVSSVSKS

LCORL

411

Q8N3X6
TLSPADQLKSTLQTL

LETM1

426

O95202
KIVTQLTSQISPLNT

FSIP2

4796

Q5CZC0
VSLLQNVTLSTQPIS

DNAAF10

311

Q96MX6
ALSVLQKSIRPQVVT

CPSF1

511

Q10570
LIKRNTTIPTKQTQT

HSPA2

416

P54652
TALIKRNSTIPTKQT

HSPA1B

411

P0DMV9
KQISAVQPSIINLSV

PCLO

2766

Q9Y6V0
SSVLTKSPLQLQTVI

LUZP6

21

Q538Z0
QGTLPLTVQKVLASQ

MLH3

1346

Q9UHC1
SPQLSSSALVQVRVL

PCDH8

586

O95206
NVALKVSVQSLPRQS

FAM214A

206

Q32MH5
QIFRALKQPLTATTL

FRYL

1831

O94915
QAARLIQESPTLSKL

LPCAT3

396

Q6P1A2
SFLKSNTLPISLQSI

LRPPRC

526

P42704
TLKTVLDQQQTPSRL

LRPPRC

1126

P42704
LPTLQALTLALNKIS

LGR4

176

Q9BXB1
EANKVLTRAPILQST

GABRA6

386

Q16445
CSQLPNQVLKSISVI

EHD4

141

Q9H223
VAKLIAALSTPSQQV

GCN1

1341

Q92616
TNLLSQPRGINTVVK

LRP2

2631

P98164
LGTVLQLKQPLNTTR

PTPN11

206

Q06124
SENIPLNTKIALITV

PCDH11X

371

Q9BZA7
ILLDVSTKNPVRTVN

HPSE2

61

Q8WWQ2
PVLSSQNILSISKLV

NBAS

1816

A2RRP1
TVVTPKTLANLLTSN

OR8H3

76

Q8N146
QLEKIRAPSNVSTII

RELN

296

P78509
PIINTFKNLSSTSVL

PTPRQ

1196

Q9UMZ3
INVKNQRVLASPTST

PRDM6

446

Q9NQX0
QLIVINPKTTLSVGV

PALB2

1091

Q86YC2
VNKDVTLTSPLLVNL

NCOA6

876

Q14686
VVKQTIFIPALNITT

F2RL1

211

P55085
TPAQLTQLKQASLSR

PXDNL

1241

A1KZ92
VITSSPLTKLQLQEA

DCP1B

571

Q8IZD4
SSIKIQPSNTLELLV

IGSF1

1046

Q8N6C5
AIKNISTLPVNLLLS

HYDIN

1076

Q4G0P3
PLRTSNVQTCLTKLS

ICE1

256

Q9Y2F5
SKSRILNTLLSPAQL

CARD6

466

Q9BX69
ALLSNTQSLLPRIVK

C3orf49

116

Q96BT1
PLVTQVTTLVNTNSK

CTNNA1

31

P35221
TVTSTVLKRLQPQTT

COL12A1

1046

Q99715
QGQSLLQLPRTAVKS

C7orf61

96

Q8IZ16
TPKQRITILQNASIT

FILIP1L

941

Q4L180
SVEISKIQLSINTPR

FANCA

696

O15360
LRITIAINNTLTPTT

GUSB

166

P08236
KQLSPATQLAIQRAT

C14orf93

221

Q9H972
TPITTLTSEQIQKLL

COL6A3

1406

P12111
VAKTSITLPQVQAIL

REXO1L1P

556

Q8IX06
LQSVPNTTTLILQKR

AWAT1

186

Q58HT5
LDPKLILQAVTLQTS

C1orf112

641

Q9NSG2
VVRINSPNSKVNTLS

HADHA

51

P40939
RSKISVLANTLINPQ

EFHB

326

Q8N7U6
SSLRPLAIQQIKAVS

GEN1

546

Q17RS7
LQTLPNGVTQKIQLT

KMT2A

3091

Q03164
TVTRLLNINPNKTSA

LAMP1

251

P11279
VTSLLQPLVASNKRS

GDF9

216

O60383
TALIKRNSTIPTKQT

HSPA1A

411

P0DMV8
TKTALLVPNALIIAT

GRAMD2B

176

Q96HH9
ISDLQTQSQPLKSLR

CDKL5

826

O76039
ILSVNVKSPALLLSQ

DHRS2

141

Q13268
KAEAPLLTQTRLITQ

SCNM1

101

Q9BWG6
FLLSPNLLQKTTIQV

PEX1

516

O43933
PTVLAKTLVQRLLNS

CARD11

981

Q9BXL7
VTLNLTSKPIILRFN

SERPINA6

366

P08185
PIQLVKTHNLLTTRN

DGAT2

141

Q96PD7
PLKSSAVSFQLQLQL

DIPK1C

361

Q0P6D2
SKVSQNPILTSLLQI

MED1

596

Q15648
VLPSRLQASQVKLKS

FANCD2

311

Q9BXW9
SPLLLVSVVRVNTTN

PCDH11Y

16

Q9BZA8
IKPTSLVQSSIQRFQ

PIAS2

161

O75928
LVRLSSAVPNQISIS

PIAS2

266

O75928
TVLIKRNTTIPTKQT

HSPA8

411

P11142
TPRLKTQQSITVQVS

PCDHB6

426

Q9Y5E3
TVPKALVNIQTQSRS

OR1P1

91

Q8NH06
ASVPTLLVNLLSSQK

OR2K2

76

Q8NGT1
LISVTAPKSIANSLI

OR14A16

71

Q8NHC5
IRIQSIAPSLQVITS

MTOR

2151

P42345
LNPTSSNLKVIIFIS

TAS2R20

71

P59543
LQTSKPLVTSVANTV

TAF4B

431

Q92750
QITLPGNKILSLQAS

TAF4B

581

Q92750
VQNSSSSKLTQPRLV

RGSL1

1041

A5PLK6
KNLVTLPNTTATAIL

RPE65

381

Q16518
QPLSENATLTLISTK

VCAM1

556

P19320
ARTSQPKQISVLEAL

SLC6A16

61

Q9GZN6
PLVSKAQLSQTVQSR

PPP4R4

176

Q6NUP7
LLPGSQQKSVTVVTI

RNF152

121

Q8N8N0
TSNIPIILQSALVSN

SEC61A2

286

Q9H9S3
ISPFKAQTLLIQVIS

PLCD4

621

Q9BRC7
CKLPITQRLSTLQDI

SYNE3

251

Q6ZMZ3
PKTVQDLTSVVQTLL

HSBP1

6

O75506
LSKNILTLIELPSVN

SMG1

1561

Q96Q15
AAITLKAINPINTFT

ARHGAP1

406

Q07960
TASLNLRTPDSKQII

SHC3

231

Q92529
AAFKILQNTSSLPVL

SIGLEC6

251

O43699
LAITSSSIPKNIQSL

ST3GAL4

101

Q11206
VGSKTNLVTINPSII

ST8SIA6

226

P61647
GNKTTIRIINSQILT

ST6GAL2

336

Q96JF0
TIQLPFIIINTSRKT

TFDP2

271

Q14188
ILAKLQTNPKLSNLT

TLR1

236

Q15399
LSTVNVILGKPVLNT

ADGRF5

796

Q8IZF2
LTLQTPTIQSLAFKL

ADGRG5

66

Q8IZF4
ITSSSLQKSPTLLRN

MLLT10

511

P55197
PLIFTTQSLIQKVET

CCDC110

461

Q8TBZ0
QISKLQSQRKSLSTP

ANKFN1

566

Q8N957
VAILVQVSKVPSSLS

CLEC4M

66

Q9H2X3
RTLLQTTTVKTLPLV

CLCN1

626

P35523
TTEPLQISQVSLISK

ZBTB25

316

P24278
QSSSILKPLLQQGLS

PIK3R4

611

Q99570
SFSELLQKTPVIQLV

TMEM138

26

Q9NPI0
KVNAPILTNTTLNVI

VPS50

601

Q96JG6
ITSSQILDQLKAPSL

UBAP2

371

Q5T6F2
TVNKLLQLPSTTIEN

UBAP2

476

Q5T6F2
IPTLITQLTQKLLAV

CSE1L

591

P55060
PTQNVRTILLSVISL

CDC34

116

P49427
QSNKPVTLTVEQSRL

TM9SF4

106

Q92544
LKSVLQSPLFSQILS

MPDZ

36

O75970
QLVLTPSIVTTNKKL

SPEN

2946

Q96T58
VQITLPTVQKALAST

NIBAN1

501

Q9BZQ8
LIQLPANSVTKVSIQ

PIGT

431

Q969N2
FVQLLSLLQTPKSTL

SPEM3

1031

A0A1B0GUW6
LLIRENQPKSSIVSL

SLC9A2

541

Q9UBY0
TSNIPIILQSALVSN

SEC61A1

286

P61619
SPAISELIQSVLQKL

SYBU

496

Q9NX95
TLSIQVLTAQQLPKL

PLCD3

661

Q8N3E9
LTKQSRQLVVSPLVS

TIE1

456

P35590
VFSPAQLTQIKQTSL

PXDN

1256

Q92626
TNSKTVNERITLNLP

USP47

51

Q96K76
SRLSNLIKLAQKVPT

GC

231

P02774
PANNTLFIVSISKTL

NF1

1901

P21359
ALLTTQNKLRTLVPN

NDST2

336

P52849
LVSTSVTIRENKNIP

VPS13C

536

Q709C8
NTSLTIRLPLAKTNL

ROS1

1461

P08922
AKVRPQTNITLQIAT

SLIT2

1176

O94813
LQNLLTTQSPSVKSL

UTP14A

561

Q9BVJ6
LNQILRIKTSLTSQV

MYH16

461

Q9H6N6
TKFVLQAAATPLLQS

ZDHHC14

366

Q8IZN3
SPGTSTQILQIVLKR

TOPAZ1

1606

Q8N9V7
PKTQASSNLLALVTR

ULK2

611

Q8IYT8
NLIPDSLLTSAQKII

ZNF507

371

Q8TCN5
TRPKLATFVTQALIQ

XPO7

96

Q9UIA9
PTQNVRTILLSVISL

UBE2R2

116

Q712K3
TIANSLVILSKGIPQ

VN1R3

51

Q9BXE9
KDLLTNVQQLLVVTP

TRIP12

646

Q14669
SSEITKNLLPATLQL

UBR4

1151

Q5T4S7
KPNSKVLSTRVTNVL

PRR11

271

Q96HE9
TLSQIRNSIVNKNTP

ZNF44

131

P15621
LPTISQRIVSAQSLA

TOMM20

126

Q15388
LSLPETLTSKIRQQS

UNC79

1241

Q9P2D8
VLTATSILNNPIVKA

ZNF326

446

Q5BKZ1
AAQATLRQTEPLTKL

LAMC3

1296

Q9Y6N6
TSENKLLQQLFSIPL

MYO3B

866

Q8WXR4
LLQQLFSIPLTKTGN

MYO3B

871

Q8WXR4
PQTIQRTVSKESLLV

MYPN

751

Q86TC9