Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF10 ZNF717 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF451 ZNF722 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	4.52e-09	1412	87	24	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF10 ZNF717 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF722 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	4.19e-08	1459	87	23	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF717 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF722 ZNF735 ZNF286B ZNF816 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	5.91e-08	1244	87	21	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF717 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF722 ZNF735 ZNF286B ZNF816 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	8.51e-08	1271	87	21	GO:0000987
GeneOntologyMolecularFunction	histone H3K4 monomethyltransferase activity	KMT2C KMT2B	5.17e-04	8	87	2	GO:0140945
GeneOntologyMolecularFunction	histone H3K4 trimethyltransferase activity	KMT2C KMT2B	8.26e-04	10	87	2	GO:0140999
GeneOntologyMolecularFunction	histone H3 methyltransferase activity	KMT2C KMT2B MECOM	9.30e-04	44	87	3	GO:0140938
GeneOntologyBiologicalProcess	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	1.76e-05	2	87	2	GO:0001988
GeneOntologyBiologicalProcess	baroreceptor response to decreased systemic arterial blood pressure	CHRFAM7A CHRNA7	5.26e-05	3	87	2	GO:0001982
GeneOntologyCellularComponent	spine apparatus membrane	CHRFAM7A CHRNA7	5.01e-05	3	86	2	GO:0098897
MousePheno	airway basal cell hyperplasia	CHRFAM7A CHRNA7	1.63e-05	2	57	2	MP:0011115
MousePheno	abnormal airway basal cell differentiation	CHRFAM7A CHRNA7	1.63e-05	2	57	2	MP:0011114
MousePheno	abnormal airway basal cell morphology	CHRFAM7A CHRNA7	1.63e-05	2	57	2	MP:0011113
MousePheno	lordokyphosis	BUB1B MECOM CLEC3B	5.02e-05	18	57	3	MP:0031253
MousePheno	abnormal nicotine-mediated receptor currents	CHRFAM7A CHRNA7	9.75e-05	4	57	2	MP:0009475
Domain	zf-C2H2	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF451 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	3.40e-13	693	85	22	PF00096
Domain	ZINC_FINGER_C2H2_2	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 CBLL2 KLF5 ZNF587 ZNF451 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	3.60e-13	775	85	23	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 CBLL2 KLF5 ZNF587 ZNF451 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	3.79e-13	777	85	23	PS00028
Domain	Znf_C2H2-like	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 CBLL2 KLF5 ZNF587 ZNF451 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	6.26e-13	796	85	23	IPR015880
Domain	Znf_C2H2	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 CBLL2 KLF5 ZNF587 ZNF451 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	7.90e-13	805	85	23	IPR007087
Domain	ZnF_C2H2	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 CBLL2 KLF5 ZNF587 ZNF451 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	8.53e-13	808	85	23	SM00355
Domain	-	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	2.13e-12	679	85	21	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	3.22e-12	694	85	21	IPR013087
Domain	KRAB	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 ZNF587 ZNF735 ZNF816 ZNF343 ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZNF417	6.90e-11	358	85	15	PS50805
Domain	KRAB	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 ZNF587 ZNF735 ZNF816 ZNF343 ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZNF417	6.90e-11	358	85	15	PF01352
Domain	KRAB	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 ZNF587 ZNF735 ZNF816 ZNF343 ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZNF417	1.05e-10	369	85	15	SM00349
Domain	KRAB	ZNF10 ZNF17 ZNF776 ZNF26 ZNF334 ZNF587 ZNF735 ZNF816 ZNF343 ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZNF417	1.09e-10	370	85	15	IPR001909
Domain	zf-C2H2_6	ZNF10 ZNF17 ZNF26 ZNF334 ZNF587 ZNF735 ZNF816 MECOM ZNF479 ZNF624 ZNF224 ZNF225 ZBTB11 ZNF417	1.40e-10	314	85	14	PF13912
Domain	Growth_fac_rcpt_	PCSK5 ERBB3 FBN1 SCUBE2 CRIM1 SLIT1 LAMA1 NOTCH3	5.52e-07	156	85	8	IPR009030
Domain	EGF-like_dom	PCSK5 FBN1 SCUBE2 SLIT1 LAMA1 ADAM29 ADAM28 NOTCH3	1.77e-05	249	85	8	IPR000742
Domain	EGF_1	FBN1 SCUBE2 SLIT1 LAMA1 ADAM29 SSPOP ADAM28 NOTCH3	2.10e-05	255	85	8	PS00022
Domain	EGF_2	FBN1 SCUBE2 SLIT1 LAMA1 ADAM29 SSPOP ADAM28 NOTCH3	2.77e-05	265	85	8	PS01186
Domain	VWC_out	CRIM1 KCP SSPOP	8.36e-05	19	85	3	SM00215
Domain	EGF_3	FBN1 SCUBE2 SLIT1 ADAM29 SSPOP ADAM28 NOTCH3	9.79e-05	235	85	7	PS50026
Domain	EGF	PCSK5 FBN1 SCUBE2 SLIT1 LAMA1 ADAM28 NOTCH3	9.79e-05	235	85	7	SM00181
Domain	EPHD	KMT2C KMT2B MLLT10	1.32e-04	22	85	3	PS51805
Domain	EGF-like_CS	FBN1 SCUBE2 SLIT1 LAMA1 ADAM29 ADAM28 NOTCH3	1.87e-04	261	85	7	IPR013032
Domain	FYrich_C	KMT2C KMT2B	2.03e-04	5	85	2	IPR003889
Domain	FYrich_N	KMT2C KMT2B	2.03e-04	5	85	2	IPR003888
Domain	FYRC	KMT2C KMT2B	2.03e-04	5	85	2	SM00542
Domain	FYRN	KMT2C KMT2B	2.03e-04	5	85	2	SM00541
Domain	FYRN	KMT2C KMT2B	2.03e-04	5	85	2	PF05964
Domain	FYRC	KMT2C KMT2B	2.03e-04	5	85	2	PF05965
Domain	FYRC	KMT2C KMT2B	2.03e-04	5	85	2	PS51543
Domain	FYRN	KMT2C KMT2B	2.03e-04	5	85	2	PS51542
Domain	GF_recep_IV	PCSK5 ERBB3	3.03e-04	6	85	2	PF14843
Domain	GF_recep_IV	PCSK5 ERBB3	3.03e-04	6	85	2	IPR032778
Domain	VWFC_1	CRIM1 KCP SSPOP	5.83e-04	36	85	3	PS01208
Domain	VWC	CRIM1 KCP SSPOP	6.84e-04	38	85	3	SM00214
Domain	VWFC_2	CRIM1 KCP SSPOP	6.84e-04	38	85	3	PS50184
Domain	VWF_dom	CRIM1 KCP SSPOP	9.19e-04	42	85	3	IPR001007
Domain	-	USP49 KMT2C KMT2B CBLL2 MKRN1 MLLT10 ZFYVE1 TRIM7	1.00e-03	449	85	8	3.30.40.10
Domain	EGF_Ca-bd_CS	FBN1 SCUBE2 SLIT1 NOTCH3	1.00e-03	97	85	4	IPR018097
Domain	EGF_CA	FBN1 SCUBE2 SLIT1 NOTCH3	1.08e-03	99	85	4	PS01187
Domain	Znf_RING/FYVE/PHD	USP49 KMT2C KMT2B CBLL2 MKRN1 MLLT10 ZFYVE1 TRIM7	1.15e-03	459	85	8	IPR013083
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN1 SCUBE2 SLIT1 NOTCH3	1.39e-03	106	85	4	IPR000152
Domain	Unchr_dom_Cys-rich	KCP SSPOP	1.55e-03	13	85	2	IPR014853
Domain	C8	KCP SSPOP	1.55e-03	13	85	2	SM00832
Domain	TIL_dom	KCP SSPOP	1.80e-03	14	85	2	IPR002919
Domain	EGF_CA	FBN1 SCUBE2 SLIT1 NOTCH3	2.33e-03	122	85	4	SM00179
Domain	Post-SET_dom	KMT2C KMT2B	2.36e-03	16	85	2	IPR003616
Domain	VWD	KCP SSPOP	2.36e-03	16	85	2	SM00216
Domain	PostSET	KMT2C KMT2B	2.36e-03	16	85	2	SM00508
Domain	VWF_type-D	KCP SSPOP	2.36e-03	16	85	2	IPR001846
Domain	Disintegrin_CS	ADAM29 ADAM28	2.36e-03	16	85	2	IPR018358
Domain	VWFD	KCP SSPOP	2.36e-03	16	85	2	PS51233
Domain	POST_SET	KMT2C KMT2B	2.36e-03	16	85	2	PS50868
Domain	VWD	KCP SSPOP	2.36e-03	16	85	2	PF00094
Domain	EGF-like_Ca-bd_dom	FBN1 SCUBE2 SLIT1 NOTCH3	2.48e-03	124	85	4	IPR001881
Domain	Furin_repeat	PCSK5 ERBB3	2.99e-03	18	85	2	IPR006212
Domain	CTCK_1	SLIT1 SSPOP	2.99e-03	18	85	2	PS01185
Domain	ADAM_CR	ADAM29 ADAM28	2.99e-03	18	85	2	PF08516
Domain	FU	PCSK5 ERBB3	2.99e-03	18	85	2	SM00261
Domain	-	ADAM29 ADAM28	3.69e-03	20	85	2	4.10.70.10
Domain	Disintegrin	ADAM29 ADAM28	4.06e-03	21	85	2	PF00200
Domain	DISIN	ADAM29 ADAM28	4.06e-03	21	85	2	SM00050
Domain	Znf_FYVE_PHD	KMT2C KMT2B MLLT10 ZFYVE1	4.55e-03	147	85	4	IPR011011
Domain	PHD	KMT2C KMT2B MLLT10	4.85e-03	75	85	3	PF00628
Domain	-	CHRFAM7A CHRNA7	4.87e-03	23	85	2	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRFAM7A CHRNA7	4.87e-03	23	85	2	IPR027361
Domain	Znf_PHD-finger	KMT2C KMT2B MLLT10	5.61e-03	79	85	3	IPR019787
Domain	Ephrin_rec_like	PCSK5 SCUBE2	5.74e-03	25	85	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	PCSK5 SCUBE2	5.74e-03	25	85	2	IPR011641
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF10 ZNF717 KMT2C ZNF17 ZNF776 ZNF26 KMT2B ZNF334 ZNF587 ZNF735 ZNF343 ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZNF417 ZNF415 NOTCH3	2.47e-05	1387	69	19	M734
Pubmed	Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance.	CHRFAM7A LEPR CHRNA7	1.57e-08	3	88	3	21239433
Pubmed	Activation of α7 nicotinic acetylcholine receptors increases intracellular cAMP levels via activation of AC1 in hippocampal neurons.	CHRFAM7A ADCY1 CHRNA7	1.57e-08	3	88	3	25937212
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF10 ZNF17 ZNF26 ZNF224	1.14e-06	31	88	4	2288909
Pubmed	Cholinergic signals preserve haematopoietic stem cell quiescence during regenerative haematopoiesis.	CHRFAM7A LEPR CHRNA7	1.85e-06	10	88	3	35087060
Pubmed	A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.	CHRFAM7A LEPR CHRNA7	2.55e-06	11	88	3	35276096
Pubmed	Defining brain wiring patterns and mechanisms through gene trapping in mice.	CRIM1 LAMA1 NOTCH3	5.58e-06	14	88	3	11242070
Pubmed	Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	38070724
Pubmed	Inflammatory cytokines decrease the expression of nicotinic acetylcholine receptor during the cell maturation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	19626424
Pubmed	Episodic memory performance predicted by the 2bp deletion in exon 6 of the "alpha 7-like" nicotinic receptor subunit gene.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	17012698
Pubmed	Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	26451017
Pubmed	Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	34453977
Pubmed	Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	24757672
Pubmed	Inhibition of pancreatic acinar mitochondrial thiamin pyrophosphate uptake by the cigarette smoke component 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	26999808
Pubmed	Positive allosteric modulators of α7 nicotinic acetylcholine receptors affect neither the function of other ligand- and voltage-gated ion channels and acetylcholinesterase, nor β-amyloid content.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	27129924
Pubmed	Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	17291692
Pubmed	Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23521765
Pubmed	Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	28258105
Pubmed	The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	19344760
Pubmed	Loss of α7nAChR enhances endothelial-to-mesenchymal transition after myocardial infarction via NF-κB activation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	35926661
Pubmed	The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	17640819
Pubmed	Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23431157
Pubmed	Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	29114104
Pubmed	Autophagy is Involved in Neuroprotective Effect of Alpha7 Nicotinic Acetylcholine Receptor on Ischemic Stroke.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	33995108
Pubmed	E-cigarette-induced pulmonary inflammation and dysregulated repair are mediated by nAChR α7 receptor: role of nAChR α7 in SARS-CoV-2 Covid-19 ACE2 receptor regulation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	32552811
Pubmed	Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	24836856
Pubmed	Modulation of the MAPKs pathways affects Aβ-induced cognitive deficits in Alzheimer's disease via activation of α7nAChR.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	31904546
Pubmed	Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	15948184
Pubmed	Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	35678315
Pubmed	Age-Associated Tooth Loss and Oral Microbial Dysbiosis in a Mouse Genetic Model of Chronic Nicotine Exposure.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	33117372
Pubmed	Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	12628457
Pubmed	Activation of α-7 nicotinic acetylcholine receptor reduces ischemic stroke injury through reduction of pro-inflammatory macrophages and oxidative stress.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	25157794
Pubmed	Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	19615981
Pubmed	Splenic nerve denervation attenuates depression-like behaviors in Chrna7 knock-out mice via the spleen-gut-brain axis.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	38944290
Pubmed	Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	28243714
Pubmed	Mesenchymal Stem Cells or Interleukin-6 Improve Episodic Memory of Mice Lacking α7 Nicotinic Acetylcholine Receptors.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	31202708
Pubmed	Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	22246862
Pubmed	Stimulation of the α7 nicotinic acetylcholine receptor protects against sepsis by inhibiting Toll-like receptor via phosphoinositide 3-kinase activation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	24298024
Pubmed	Lung eosinophilia induced by house dust mites or ovalbumin is modulated by nicotinic receptor α7 and inhibited by cigarette smoke.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	29975102
Pubmed	α7-nAChR Knockout Mice Decreases Biliary Hyperplasia and Liver Fibrosis in Cholestatic Bile Duct-Ligated Mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	29580318
Pubmed	Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	35479080
Pubmed	[Activation of α7 nAChR improves white fat homeostasis and promotes beige adipogenesis and thermogenesis in obese mice].	CHRFAM7A CHRNA7	6.33e-06	2	88	2	38597441
Pubmed	Activation of Nicotinic Acetylcholine Receptors Decreases Apoptosis in Human and Female Murine Pancreatic Islets.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	27471776
Pubmed	Targeting α-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	22688057
Pubmed	α7 Nicotinic acetylcholine receptor agonist attenuates neuropathological changes associated with intracerebral hemorrhage in mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	22820264
Pubmed	Stimulation of α7-nAChRs coordinates autophagy and apoptosis signaling in experimental knee osteoarthritis.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	33953172
Pubmed	Different Effects of Nicotine and N-Stearoyl-ethanolamine on Episodic Memory and Brain Mitochondria of α7 Nicotinic Acetylcholine Receptor Knockout Mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	32028688
Pubmed	Genetic variation in CHRNA7 and CHRFAM7A is associated with nicotine dependence and response to varenicline treatment.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	30089821
Pubmed	Nicotinic acetylcholine receptor activation reduces skeletal muscle inflammation of mdx mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	20615555
Pubmed	Nicotine physical dependence in the mouse: involvement of the alpha7 nicotinic receptor subtype.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	15896732
Pubmed	Activation of α7 Nicotinic Acetylcholine Receptor Ameliorates Zymosan-Induced Acute Kidney Injury in BALB/c Mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	30429582
Pubmed	A transgenic mouse model reveals fast nicotinic transmission in hippocampal pyramidal neurons.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	21501254
Pubmed	α7-cholinergic receptor mediates vagal induction of splenic norepinephrine.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	21339364
Pubmed	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	21368056
Pubmed	Genetic variation within the Chrna7 gene modulates nicotine reward-like phenotypes in mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	24289814
Pubmed	Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	19949071
Pubmed	Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	1400473
Pubmed	Reversible inhibition of GABAA receptors by alpha7-containing nicotinic receptors on the vertebrate postsynaptic neurons.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	17204496
Pubmed	Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	26937017
Pubmed	α7 nicotinic receptors play a role in regulation of cardiac hemodynamics.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	37017608
Pubmed	Impaired hippocampal theta oscillations in the mice null alpha7 nicotinic acetylcholine receptors.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23795917
Pubmed	Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	36603528
Pubmed	Endogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	20592195
Pubmed	Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	26650489
Pubmed	Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	11854451
Pubmed	Lack of modulation of nicotinic acetylcholine alpha-7 receptor currents by kynurenic acid in adult hippocampal interneurons.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	22848433
Pubmed	Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23842742
Pubmed	Abeta(1-42) modulation of Akt phosphorylation via alpha7 nAChR and NMDA receptors.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	17292512
Pubmed	Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	16650968
Pubmed	Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	35413868
Pubmed	Circulating brain microvascular endothelial cells (cBMECs) as potential biomarkers of the blood-brain barrier disorders caused by microbial and non-microbial factors.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23637989
Pubmed	Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7).	CHRFAM7A CHRNA7	6.33e-06	2	88	2	9782083
Pubmed	Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	24462939
Pubmed	Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	29261717
Pubmed	Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.	FBN1 NOTCH3	6.33e-06	2	88	2	32616814
Pubmed	Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	18199426
Pubmed	Stroke-induced activation of the α7 nicotinic receptor increases Pseudomonas aeruginosa lung injury.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	22490926
Pubmed	Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	36997969
Pubmed	A phenotype for the alpha 7 nicotinic acetylcholine receptor null mutant.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	15364017
Pubmed	Choline, an alpha7 nicotinic acetylcholine receptor agonist, alleviates hyperalgesia in a rat osteoarthritis model.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23769729
Pubmed	Mice deficient in CHRNA7, a subunit of the nicotinic acetylcholine receptor, produce sperm with impaired motility.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	15944242
Pubmed	Dendritic spine alterations in the hippocampus and parietal cortex of alpha7 nicotinic acetylcholine receptor knockout mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23270857
Pubmed	Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	18077004
Pubmed	Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	19462340
Pubmed	Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memory.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	16923147
Pubmed	NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	11790782
Pubmed	A role of the subdiaphragmatic vagus nerve in depression-like phenotypes in mice after fecal microbiota transplantation from Chrna7 knock-out mice with depression-like phenotypes.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	33422641
Pubmed	Nicotinic ACh receptor α7 inhibits PDGF-induced migration of vascular smooth muscle cells by activating mitochondrial deacetylase sirtuin 3.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	30270436
Pubmed	Activation of α-7 Nicotinic Acetylcholine Receptor Attenuates Cardiac Inflammation Through NLRP3/Caspase-1/IL-18 Pathway.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	34988776
Pubmed	Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	37746145
Pubmed	A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	19631623
Pubmed	Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	15770102
Pubmed	Cortical synaptic NMDA receptor deficits in α7 nicotinic acetylcholine receptor gene deletion models: implications for neuropsychiatric diseases.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	24326163
Pubmed	Loss of α7 nicotinic acetylcholine receptors in GABAergic neurons causes sex-dependent decreases in radial glia-like cell quantity and impairments in cognitive and social behavior.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	33398432
Pubmed	Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: studies in transgenic mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23811428
Pubmed	beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	20374280
Pubmed	Proteome profile of the cerebellum from α7 nicotinic acetylcholine receptor deficient mice.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	38185761
Pubmed	Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	20720594
Pubmed	α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	22624500
Pubmed	Involvement of acetylcholine-α7nAChR in the protective effects of arterial baroreflex against ischemic stroke.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	23106973
Pubmed	Suppression of neuroinflammation by an allosteric agonist and positive allosteric modulator of the α7 nicotinic acetylcholine receptor GAT107.	CHRFAM7A CHRNA7	6.33e-06	2	88	2	33902624
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF17 FAM187B ZNF776 KMT2B ZNF587 ZNF816 ZNF470 ZNF224 ZNF225 ZNF417 ZNF415 KLC3	2.97e-06	1192	88	12	chr19q13
Cytoband	19q13.43	ZNF776 ZNF587 ZNF470 ZNF417	2.48e-05	87	88	4	19q13.43
Cytoband	2p21	LRPPRC CRIM1 PLEKHH2	2.26e-04	61	88	3	2p21
Cytoband	7q36.1	KMT2C XRCC2 SSPOP	4.00e-04	74	88	3	7q36.1
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF10 ZNF717 ZNF17 ZNF776 ZNF26 ZNF334 KLF5 ZNF587 ZNF451 ZNF735 ZNF286B ZNF816 ZNF343 ZFHX2 MECOM ZNF479 ZNF624 ZNF470 ZNF224 ZNF225 ZBTB11 ZNF417 ZNF415	1.98e-16	718	65	23	28
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2C KMT2B MECOM	2.45e-04	34	65	3	487
Coexpression	NABA_ECM_GLYCOPROTEINS	VTN FBN1 CRIM1 SLIT1 LAMA1 KCP SSPOP	3.23e-06	191	86	7	MM17059
Coexpression	NABA_ECM_GLYCOPROTEINS	VTN FBN1 CRIM1 SLIT1 LAMA1 KCP SSPOP	3.83e-06	196	86	7	M3008
Coexpression	NABA_MATRISOME	PCSK5 VTN FBN1 SCUBE2 CRIM1 P3H2 SLIT1 LAMA1 KCP ADAM29 CLEC3B SSPOP ADAM28	2.40e-05	1008	86	13	MM17056
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HOPC	ERBB3 SCUBE2 KCND2 BUB1B PLEKHH2 CHN1 SSPOP OPHN1	2.75e-05	366	86	8	M39052
Coexpression	NABA_MATRISOME	PCSK5 VTN FBN1 SCUBE2 CRIM1 P3H2 SLIT1 LAMA1 KCP ADAM29 CLEC3B SSPOP ADAM28	2.89e-05	1026	86	13	M5889
Coexpression	NABA_CORE_MATRISOME	VTN FBN1 CRIM1 SLIT1 LAMA1 KCP SSPOP	3.06e-05	270	86	7	MM17057
Coexpression	NABA_CORE_MATRISOME	VTN FBN1 CRIM1 SLIT1 LAMA1 KCP SSPOP	3.44e-05	275	86	7	M5884
Coexpression	DESCARTES_ORGANOGENESIS_NEURAL_TUBE	SCUBE2 CHRFAM7A CHRNA7	3.73e-05	20	86	3	MM3659
Coexpression	BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	TPK1 PCSK5 VTN PPP6C KCND2 ZDHHC6 TNFRSF8 MKRN1 ENC1 ECI1 DNAJC7	5.20e-05	786	86	11	M2388
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRR16 FBN1 PRICKLE2 RIPOR3 PLEKHH2 ADAM28	1.08e-06	169	88	6	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VTN CRIM1 CHN1 DNAJC6 SSPOP NOTCH3	1.32e-06	175	88	6	2a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VTN CRIM1 CHN1 DNAJC6 SSPOP NOTCH3	1.32e-06	175	88	6	fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB3 CRIM1 MECOM ADAM29 CD46 CHN1	1.37e-06	176	88	6	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PRR16 CRIM1 KCP ZNF479 CHN1 NOTCH3	2.00e-06	188	88	6	ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	SCUBE2 ENC1 SLC39A6 MECOM ADAM28 NOTCH3	2.13e-06	190	88	6	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	PRR16 FBN1 MECOM RIPOR3 ADCY1 OPHN1	2.13e-06	190	88	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN FBN1 KCP CLEC3B CHN1 NOTCH3	2.20e-06	191	88	6	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 PRR16 FBN1 MECOM CLEC3B CHN1	2.20e-06	191	88	6	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 KCP CHN1 LEPR NOTCH3	2.26e-06	192	88	6	158cc5736f154da1cb3186ffbf186eae10483e48
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 KCP CHN1 LEPR NOTCH3	2.26e-06	192	88	6	f4ff62ac9c53eafbe917706de9af8b2d4bded4d4
ToppCell	LA\|World / Chamber and Cluster_Paper	PCSK5 NWD2 FBN1 KCND2 PRICKLE2 PLEKHH2	2.33e-06	193	88	6	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	PCSK5 FBN1 KCND2 PRICKLE2 PLEKHH2 OPHN1	2.48e-06	195	88	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FBN1 ENC1 PLEKHH2 CHN1 LEPR	2.63e-06	197	88	6	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PRR16 FBN1 P3H2 PLEKHH2 LEPR NOTCH3	2.78e-06	199	88	6	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PRR16 FBN1 P3H2 PLEKHH2 LEPR NOTCH3	2.78e-06	199	88	6	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PRR16 FBN1 P3H2 PLEKHH2 LEPR NOTCH3	2.78e-06	199	88	6	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	PND01-03-samps-Mesenchymal-Pericyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	VTN CRIM1 CHN1 LEPR NOTCH3	1.29e-05	152	88	5	fc9472bc19f997103da535b035105f01429cb08e
ToppCell	Club_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ERBB3 FBN1 SCUBE2 ZNF415 NOTCH3	1.60e-05	159	88	5	a7bcff268b1962a561fd2848e01ae16565bce895
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERBB3 KLF5 PRICKLE2 MECOM MAP3K13	1.97e-05	166	88	5	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 FBN1 BUB1B XRCC2 NOTCH3	2.27e-05	171	88	5	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF343 LEPR NOTCH3 OPHN1 TRIM7	2.27e-05	171	88	5	6a2f88c2a62cb2f69797804e24eb1137a3e148de
ToppCell	356C-Endothelial_cells-Endothelial-B_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	ZNF343 LEPR NOTCH3 OPHN1 TRIM7	2.27e-05	171	88	5	9be3554626408bb897d1f1c43b3ab4a92651f2e2
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VTN LAMA1 RIPOR3 CLEC3B LEPR	2.27e-05	171	88	5	2e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 FBN1 BUB1B XRCC2 NOTCH3	2.27e-05	171	88	5	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	frontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VTN LAMA1 RIPOR3 CLEC3B LEPR	2.27e-05	171	88	5	e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRR16 SCUBE2 KCND2 TNFRSF8 ADCY1	2.40e-05	173	88	5	ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCND2 CLEC3B CD46 CHN1 NOTCH3	2.54e-05	175	88	5	59249c9e83952d7277010e7be3c779e26399eb5d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCND2 CLEC3B CD46 CHN1 NOTCH3	2.54e-05	175	88	5	b35cc1357495f2a03a6500f807c6e6f8c877734d
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VTN CRIM1 CHN1 SSPOP NOTCH3	2.61e-05	176	88	5	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VTN CRIM1 CHN1 SSPOP NOTCH3	2.61e-05	176	88	5	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	droplet-Lung-nan-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN KCP CHN1 SSPOP NOTCH3	2.68e-05	177	88	5	65709bd546cb1ec6aa2ddd8b2adb46e174eb9a9a
ToppCell	primary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VTN LAMA1 RIPOR3 CLEC3B LEPR	2.68e-05	177	88	5	599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCell	droplet-Lung-nan-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VTN KCP CHN1 SSPOP NOTCH3	2.68e-05	177	88	5	8684d47a547e2a06496f15e8da0200ecddc431e0
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 CHN1 LEPR NOTCH3	2.83e-05	179	88	5	56db12467b445f2b8ef92af50779eeab10413eb2
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF717 NBAS ZNF17 ZNF816 ADAM28	2.90e-05	180	88	5	9f4bbaf6435c23e3e552ae22be8ea7884314192d
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF717 NBAS ZNF17 ZNF816 ADAM28	2.90e-05	180	88	5	b465f2f8b0e9a2034a4f1272bb00c77439164dbf
ToppCell	BAL-Severe-Lymphocyte-B-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF717 NBAS ZNF17 ZNF816 ADAM28	2.90e-05	180	88	5	c3c72531af5b9f7a7416727fe609dab5180e03b6
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB3 VTN KLF5 ENC1 MECOM	2.98e-05	181	88	5	c1203787cc3f968147fabdd3c646a04be96f6552
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NWD2 KCND2 ENC1 PLEKHA2 CHN1	2.98e-05	181	88	5	57994ff4ecffb15653aee00644d9f887f5e3461d
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB3 VTN KLF5 ENC1 MECOM	2.98e-05	181	88	5	f7258af89f4cc89446ff6754bdaa769320af95d6
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRR16 FBN1 SCUBE2 PRICKLE2 PLEKHH2	3.06e-05	182	88	5	3dfa9187e9d2bab1d199079d29209c4648220ada
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	PRR16 CRIM1 KCP CHN1 NOTCH3	3.14e-05	183	88	5	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	E12.5-Epithelial-airway_epithelial_cell-club_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAM187B KLF5 MECOM ADAM28 KLC3	3.22e-05	184	88	5	a69c3c57cd939b2888f548a0fbca3392ad310445
ToppCell	E12.5-Epithelial-airway_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FAM187B KLF5 MECOM ADAM28 KLC3	3.22e-05	184	88	5	3df78b17098b50e1a7f2c8791bf2d0806328330a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	CRIM1 KLF5 PRICKLE2 MECOM MAP3K13	3.31e-05	185	88	5	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PMS1 NWD2 GJD2 CLEC3B ADCY1	3.31e-05	185	88	5	cdd75abdaa1ecedfd2e636203b83a6ac1782f0c3
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Mega-Mast\|bone_marrow / Manually curated celltypes from each tissue	ZNF334 PRICKLE2 RIPOR3 XRCC2 DNAJC6	3.31e-05	185	88	5	a62ebaff92f2ed27b27b32c27c89cfbe2cb35116
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	FBN1 KCP ZNF624 ZNF470 ANKRD16	3.40e-05	186	88	5	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	FBN1 KCP ZNF624 ZNF470 ANKRD16	3.40e-05	186	88	5	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	PRR16 CRIM1 KCP CHN1 NOTCH3	3.48e-05	187	88	5	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	PRR16 FBN1 PLEKHH2 CHN1 LEPR	3.48e-05	187	88	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ERBB3 P3H2 KLF5 MECOM MAP3K13	3.57e-05	188	88	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 PRR16 FBN1 MECOM CLEC3B	3.66e-05	189	88	5	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 CHN1 LEPR NOTCH3	3.66e-05	189	88	5	ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 CHN1 LEPR NOTCH3	3.76e-05	190	88	5	7e4d80a3a7f83b6a50f1d0fe82fb6c242c39d5b0
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 CHN1 LEPR NOTCH3	3.76e-05	190	88	5	1004e89d99c9d46c78b7d3532d8d4aadb81a96fd
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 PRR16 FBN1 MECOM CLEC3B	3.76e-05	190	88	5	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VTN CRIM1 CHN1 LEPR NOTCH3	3.76e-05	190	88	5	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 CHN1 LEPR NOTCH3	3.76e-05	190	88	5	7fec459cd2ad12c2923a03d098289337c0a4c1d3
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VTN CRIM1 CHN1 LEPR NOTCH3	3.76e-05	190	88	5	10b02c62e72bfea9767e3e751011436925da823e
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VTN CRIM1 CHN1 LEPR NOTCH3	3.85e-05	191	88	5	ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 VTN P3H2 CHN1 NOTCH3	3.85e-05	191	88	5	fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	P3H2 LAMA1 KCP MECOM PLEKHH2	3.85e-05	191	88	5	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	P3H2 LAMA1 KCP MECOM PLEKHH2	3.85e-05	191	88	5	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VTN CRIM1 CHN1 LEPR NOTCH3	3.85e-05	191	88	5	2ad717b59215ad8d933e9637d363b65d7298e5d4
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	VTN CRIM1 CHN1 LEPR NOTCH3	3.95e-05	192	88	5	063e119c4b58957643908f667e6cfd6f7517fd03
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	PRR16 FBN1 PRICKLE2 PLEKHH2 CHN1	4.05e-05	193	88	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	FBN1 PRICKLE2 MECOM PLEKHH2 OPHN1	4.05e-05	193	88	5	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB3 P3H2 KLF5 MECOM MAP3K13	4.05e-05	193	88	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	nucseq-Mesenchymal-Myocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PRR16 FBN1 KCND2 CHN1 NOTCH3	4.15e-05	194	88	5	2d66091097e106c7bee22e5281f50724700bdf8d
ToppCell	NS-moderate-d_16-33-Epithelial-Secretory\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ERBB3 KLF5 MECOM ADAM28 TRIM7	4.36e-05	196	88	5	70384c1da9baed843f414cfd1403ddd586a2db07
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRR16 FBN1 PRICKLE2 PLEKHH2 ADAM28	4.36e-05	196	88	5	2ab9735aa7a7e95dcf6b0bdf0427f7b57f6349ee
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FBN1 ZNF225 PLEKHH2 CHN1 NOTCH3	4.36e-05	196	88	5	614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PCSK5 FBN1 MECOM CLEC3B LEPR	4.46e-05	197	88	5	ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 FBN1 PLEKHH2 LEPR NOTCH3	4.46e-05	197	88	5	5afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 FBN1 PLEKHH2 LEPR NOTCH3	4.46e-05	197	88	5	1baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCell	10x3'2.3-week_17-19-Mesenchymal_adipo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 FBN1 PLEKHH2 LEPR NOTCH3	4.46e-05	197	88	5	b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ERBB3 P3H2 KLF5 MECOM CD46	4.57e-05	198	88	5	1eb49b853a9e144e840c660060473fc7873f6478
ToppCell	distal-Endothelial-Artery-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCSK5 TNFRSF8 MECOM CLEC3B LEPR	4.57e-05	198	88	5	f284f59f4ebe55ee132eddfaa2f5d9ecb059654f
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ERBB3 SCUBE2 SLC39A6 MECOM CHN1	4.57e-05	198	88	5	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 FBN1 PLEKHH2 LEPR NOTCH3	4.57e-05	198	88	5	a8c21f4db6730d0aa05b61fbe72bf9f7571a9015
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 FBN1 PLEKHH2 LEPR NOTCH3	4.57e-05	198	88	5	8b68fc887e5ad0a59ea4d93dfd1edda67030f142
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	PCSK5 PRR16 FBN1 RIPOR3 PLEKHH2	4.57e-05	198	88	5	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	10x3'2.3-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PCSK5 FBN1 PLEKHH2 LEPR NOTCH3	4.57e-05	198	88	5	4739b2e4ab141c66772e61686b45614a1839483e
ToppCell	distal-Endothelial-Artery\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PCSK5 TNFRSF8 MECOM CLEC3B LEPR	4.68e-05	199	88	5	b6e9aaac047d4b64b9d97f5e174e89a424d8b36d
ToppCell	10x5'v1-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FBN1 P3H2 PLEKHH2 LEPR NOTCH3	4.68e-05	199	88	5	6200618e029063486719479c41eaf31798bd13cf
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 CRIM1 KCP CHN1 NOTCH3	4.68e-05	199	88	5	929f809579368201331d9099d8904b6e3c41797b
ToppCell	Bronchial-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 CRIM1 KCP CHN1 NOTCH3	4.68e-05	199	88	5	854628ce91068093c14bd4d45ba38c41469f3549
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CRIM1 KCP PLEKHH2 CHN1 NOTCH3	4.79e-05	200	88	5	cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRR16 FBN1 PLEKHH2 CHN1 LEPR	4.79e-05	200	88	5	fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FAM187B LAMA1 RIPOR3 CLEC3B	7.22e-05	112	88	4	153614f307525af56501ac8f9c357c5f7de7882c
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Inmt_(Inmt)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FAM187B LAMA1 RIPOR3 CLEC3B	7.22e-05	112	88	4	ba0bd3a77c4865a71fb92d195cd7459c562b63db
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	FAM187B LAMA1 RIPOR3 CLEC3B	7.22e-05	112	88	4	f9a796b4b5e227096ab360ca9ec08b1c564ac1eb
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LAMA1 BUB1B RIPOR3 CLEC3B	1.14e-04	126	88	4	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LAMA1 BUB1B RIPOR3 CLEC3B	1.14e-04	126	88	4	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LAMA1 BUB1B RIPOR3 CLEC3B	1.14e-04	126	88	4	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LAMA1 BUB1B RIPOR3 CLEC3B	1.14e-04	126	88	4	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	LAMA1 BUB1B RIPOR3 CLEC3B	1.14e-04	126	88	4	2de551d7a8765afec1da8852727c79fec90f45f8
ToppCell	Tracheal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF343 ZNF470 CHN1	1.17e-04	48	88	3	0b71435d798c6b25089a16b25d1d535f3c780d30
Disease	Congenital exomphalos	PCSK5 CHRNA7	6.55e-06	2	76	2	C1306503
Disease	Congenital omphalocele	PCSK5 CHRNA7	6.55e-06	2	76	2	C0795690
Disease	cognitive disorder (implicated_via_orthology)	CHRFAM7A CHRNA7	9.75e-05	6	76	2	DOID:1561 (implicated_via_orthology)
Disease	rheumatoid arthritis (biomarker_via_orthology)	CHRFAM7A CHRNA7	9.75e-05	6	76	2	DOID:7148 (biomarker_via_orthology)
Disease	Squamous cell carcinoma of esophagus	KMT2C BUB1B SLC39A6 NOTCH3	1.08e-04	95	76	4	C0279626
Disease	Stage IV Skin Melanoma	ADAM29 ADAM28	1.36e-04	7	76	2	C1321872
Disease	lung adenocarcinoma (is_implicated_in)	KMT2C ERBB3 ADAM28	2.78e-04	49	76	3	DOID:3910 (is_implicated_in)
Disease	Atypical Hemolytic Uremic Syndrome	VTN CD46	2.91e-04	10	76	2	C2931788
Disease	nicotine dependence (implicated_via_orthology)	CHRFAM7A CHRNA7	4.25e-04	12	76	2	DOID:0050742 (implicated_via_orthology)
Disease	lung non-small cell carcinoma (is_implicated_in)	KMT2C ERBB3 ADAM28 CHRNA7	4.65e-04	139	76	4	DOID:3908 (is_implicated_in)
Disease	Breast Carcinoma	ERBB3 SLC39A6 MECOM MAP3K13 XRCC2 LEPR NOTCH3	4.76e-04	538	76	7	C0678222
Disease	Myopia	GJD2 P3H2	6.73e-04	15	76	2	C0027092
Disease	Leukemia, Myelocytic, Acute	KMT2C MECOM XRCC2 MLLT10	1.05e-03	173	76	4	C0023467
Disease	Immunologic Deficiency Syndromes	NBAS LEPR	1.60e-03	23	76	2	C0021051
Disease	stomach carcinoma (is_marker_for)	KMT2C ERBB3	1.74e-03	24	76	2	DOID:5517 (is_marker_for)
Disease	Endogenous Hyperinsulinism	FBN1 LEPR	2.04e-03	26	76	2	C1257963
Disease	Exogenous Hyperinsulinism	FBN1 LEPR	2.04e-03	26	76	2	C1257964
Disease	Compensatory Hyperinsulinemia	FBN1 LEPR	2.04e-03	26	76	2	C1257965
Disease	indole-3-propionate measurement	NBAS SLIT1	2.20e-03	27	76	2	EFO_0010501
Disease	Colorectal Carcinoma	KMT2C KLF5 LAMA1 BUB1B ZNF624 ADAM29 CD46	2.21e-03	702	76	7	C0009402
Disease	Mammary Carcinoma, Human	ERBB3 SLC39A6 MECOM XRCC2 LEPR NOTCH3	2.35e-03	525	76	6	C4704874
Disease	Mammary Neoplasms, Human	ERBB3 SLC39A6 MECOM XRCC2 LEPR NOTCH3	2.35e-03	525	76	6	C1257931
Disease	Hyperinsulinism	FBN1 LEPR	2.37e-03	28	76	2	C0020459
Disease	Mammary Neoplasms	ERBB3 SLC39A6 MECOM XRCC2 LEPR NOTCH3	2.40e-03	527	76	6	C1458155

Protein segments in the cluster

Peptide	Gene	Start	Entry
LGNEDYCIKREYLIC	BUB1B	761	O60566
VEDGIPCKERGYCYE	ADAM29	481	Q9UKF5
YKYPDVQNECRPCHE	ERBB3	601	P21860
LKRCQYEPDYRDNCG	ANKRD16	191	Q6P6B7
PGLYECNRYPCIKEV	GJD2	226	Q9UKL4
LGSCIEKARPYYEAR	SH3BP5L	106	Q7L8J4
YGYCRRVDDTLIPCK	ADAM28	541	Q9UKQ2
DKVGYKVCPRCRYPV	CBLL2	86	Q8N7E2
SERFYECCKEPYPDV	CHRNA7	206	P36544
RRKAFCLEDPYLNGC	NWD2	771	Q9ULI1
CYLDSPDFRERLKCY	OPHN1	11	O60890
GEQPYRCKYCDRSFS	MECOM	936	Q03112
DRINRADYCPECYPD	TOR1AIP2	41	Q9H496
SCPVCYRNYREEDLI	KMT2C	1086	Q8NEZ4
PGNFRCRDEKCVYET	LRP10	401	Q7Z4F1
DDACYRETCPYIRDP	CD46	91	P15529
QLYCDRYLCDKVVPG	MCM5	246	P33992
GKECLLQCREGYYAD	PCSK5	1546	Q92824
GGRERTCNPVYEKYC	NOTCH3	1461	Q9UM47
PEIIGDCCYEEYKDR	KCND2	126	Q9NZV8
DCCYEEYKDRRRENA	KCND2	131	Q9NZV8
PRGKFTYDAVYCCNE	LEPR	401	P48357
TELLYKDGRYCQEPR	LRPPRC	561	P42704
YGKRGRYREAEPLCQ	KLC3	301	Q6P597
DYSLCPRCTQLYEKG	KMT2B	1321	Q9UMN6
ECRTLCEGPQRFEEY	P3H2	246	Q8IVL5
CYDLLECLPERGYGD	NBAS	1011	A2RRP1
SERFYECCKEPYPDV	CHRFAM7A	116	Q494W8
EFGKYAIYCQRCVER	PLEKHH2	1076	Q8IVE3
ADAYDPCLQCRPEQY	MAP3K13	726	O43283
KECREDYYPGRLRSQ	PRICKLE2	466	Q7Z3G6
CDYRILADNPRYCIG	ECI1	161	P42126
ENHCRRIKILGDCYY	ADCY1	341	Q08828
GSYECKCPVGYVLRE	FBN1	2226	P35555
CRPYCDVLIGETKIY	DNAJC6	251	O75061
CGEINCERYYVPEGE	CRIM1	371	Q9NZV1
RGLCLYYEDCIEKAV	DNAJC7	216	Q99615
YFGIQRCKTLDCYDP	ENC1	546	O14682
EPGECKRLGYRYIEE	FAM187B	156	Q17R55
TCEVENRPKYYGREF	CHN1	36	P15882
YYDGARERCILCPNG	SCUBE2	646	Q9NQ36
YECRPRKVISYLEGE	PMS1	866	P54277
KQLCPYAAVGECRYG	MKRN1	211	Q9UHC7
TICYFKCEQDREPLR	PLEKHA2	226	Q9HB19
DKEPFYLRCLAAVCG	SSPOP	776	A2VEC9
ICRPGCDYEGQLYEE	KCP	191	Q6ZWJ8
EKCDRCQLGYKDYPT	LAMA1	436	P25391
YCPDCDTRYNIKNRE	PRR16	216	Q569H4
ECPRDDACTRKSYVY	SLCO1B7	476	G3V0H7
EVYNEYVPRGCKNKC	SLC39A6	526	Q13433
DRYNKTCYICDEQGR	MLLT10	131	P55197
DPMLDERGYCCIYCR	TNMD	256	Q9H2S6
VRYKVIEDYSGACCP	ZDHHC6	316	Q9H6R6
EKFILRGYCPDCNQV	ZNF451	356	Q9Y4E5
EKPYLCNECGESFRI	ZNF624	581	Q9P2J8
YPKEEELYACQRGCR	TMEM59	61	Q9BXS4
EEKPYLCRECGQSFR	ZNF343	321	Q6P1L6
PYRCNICGKEFYEKA	ZBTB11	821	O95625
PFKLYCQDDGRAICV	TRIM7	136	Q9C029
EKPYACEECGQAFRR	ZNF735	266	P0CB33
ERPYECNECGRTYCR	ZNF334	541	Q9HCZ1
KPYECNQCGKTYRRL	ZNF334	626	Q9HCZ1
LAAQRTDCPYCDVKY	ZFHX2	2141	Q9C0A1
ELYEDYCIQCRLRDG	RIPOR3	141	Q96MK2
CKYLPENDLKRLCDY	PPP6C	16	O00743
DKRCRDQLPYICQFG	CLEC3B	186	P05452
RPYECKECGKSFRYR	ZNF587	406	Q96SQ5
RPYECKECGKSFRYR	ZNF417	406	Q8TAU3
CYLCKDYVLNDNPEG	USP49	76	Q70CQ1
RPTDCRKQCEPDYYL	TNFRSF8	61	P28908
GSGDCRKQCEPDYYL	TNFRSF8	236	P28908
RPYECIDCGKAFRQN	ZNF470	366	Q6ECI4
LCDVDIDYRPYLCKA	XRCC2	216	O43543
DNRVYTCKACYERGE	ZFYVE1	466	Q9HBF4
EKPYTCEECGQAFRR	ZNF479	266	Q96JC4
CEECGKRFIYRQDLY	ZNF225	346	Q9UK10
ERPYECNECGKTFRQ	ZNF717	616	Q9BY31
RVRPYECNECGKSYS	ZNF10	401	P21506
KSCIREKPYRYIECD	ZNF415	256	Q09FC8
EKPYECNECEKAYPR	ZNF26	451	P17031
GVRPYECNECDKAFI	ZNF286B	351	P0CG31
PYKCEDCGKGYNRRL	ZNF224	651	Q9NZL3
EVYRCACPSGYKGRD	SLIT1	946	O75093
RGQYCYELDEKAVRP	VTN	176	P04004
GRKPCEYQECRQKAY	ZNF861P	61	O60384
RPYECSECGKLFRYN	ZNF17	216	P17021
RPEVREYYATKGCEL	TPK1	76	Q9H3S4
PYKCEECDNVYIRRS	ZNF816	396	Q0VGE8
EKPYTCEECGQAFRR	ZNF722	266	A0A1W2PQL4
ERPYECKECRKSFRY	ZNF776	401	Q68DI1
DLEKRRIHYCDYPGC	KLF5	366	Q13887