| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | histone H3K4 monomethyltransferase activity | 4.91e-05 | 8 | 27 | 2 | GO:0140945 | |
| GeneOntologyMolecularFunction | histone H3K4 trimethyltransferase activity | 7.87e-05 | 10 | 27 | 2 | GO:0140999 | |
| GeneOntologyMolecularFunction | unmethylated CpG binding | 7.87e-05 | 10 | 27 | 2 | GO:0045322 | |
| GeneOntologyMolecularFunction | histone H3K4 methyltransferase activity | 3.30e-04 | 20 | 27 | 2 | GO:0042800 | |
| GeneOntologyMolecularFunction | histone H3 methyltransferase activity | 1.61e-03 | 44 | 27 | 2 | GO:0140938 | |
| GeneOntologyMolecularFunction | histone modifying activity | 3.55e-03 | 229 | 27 | 3 | GO:0140993 | |
| GeneOntologyMolecularFunction | protein-lysine N-methyltransferase activity | 3.80e-03 | 68 | 27 | 2 | GO:0016279 | |
| GeneOntologyMolecularFunction | lysine N-methyltransferase activity | 3.91e-03 | 69 | 27 | 2 | GO:0016278 | |
| GeneOntologyMolecularFunction | histone methyltransferase activity | 4.13e-03 | 71 | 27 | 2 | GO:0042054 | |
| GeneOntologyCellularComponent | histone methyltransferase complex | 9.64e-05 | 75 | 25 | 3 | GO:0035097 | |
| GeneOntologyCellularComponent | methyltransferase complex | 2.84e-04 | 108 | 25 | 3 | GO:0034708 | |
| GeneOntologyCellularComponent | MLL1/2 complex | 7.09e-04 | 33 | 25 | 2 | GO:0044665 | |
| Domain | MeTrfase_trithorax | 1.86e-06 | 2 | 26 | 2 | IPR016569 | |
| Domain | FYrich_C | 1.86e-05 | 5 | 26 | 2 | IPR003889 | |
| Domain | FYrich_N | 1.86e-05 | 5 | 26 | 2 | IPR003888 | |
| Domain | FYRC | 1.86e-05 | 5 | 26 | 2 | SM00542 | |
| Domain | FYRN | 1.86e-05 | 5 | 26 | 2 | SM00541 | |
| Domain | FYRN | 1.86e-05 | 5 | 26 | 2 | PF05964 | |
| Domain | FYRC | 1.86e-05 | 5 | 26 | 2 | PF05965 | |
| Domain | FYRC | 1.86e-05 | 5 | 26 | 2 | PS51543 | |
| Domain | FYRN | 1.86e-05 | 5 | 26 | 2 | PS51542 | |
| Domain | zf-CXXC | 1.02e-04 | 11 | 26 | 2 | PF02008 | |
| Domain | Znf_CXXC | 1.02e-04 | 11 | 26 | 2 | IPR002857 | |
| Domain | ZF_CXXC | 1.02e-04 | 11 | 26 | 2 | PS51058 | |
| Domain | Post-SET_dom | 2.21e-04 | 16 | 26 | 2 | IPR003616 | |
| Domain | PostSET | 2.21e-04 | 16 | 26 | 2 | SM00508 | |
| Domain | POST_SET | 2.21e-04 | 16 | 26 | 2 | PS50868 | |
| Domain | EPHD | 4.23e-04 | 22 | 26 | 2 | PS51805 | |
| Domain | AT_hook | 6.40e-04 | 27 | 26 | 2 | SM00384 | |
| Domain | AT_hook_DNA-bd_motif | 6.40e-04 | 27 | 26 | 2 | IPR017956 | |
| Domain | SET | 1.48e-03 | 41 | 26 | 2 | PF00856 | |
| Domain | SET | 1.86e-03 | 46 | 26 | 2 | SM00317 | |
| Domain | SET_dom | 2.19e-03 | 50 | 26 | 2 | IPR001214 | |
| Domain | SET | 2.19e-03 | 50 | 26 | 2 | PS50280 | |
| Domain | - | 3.24e-03 | 449 | 26 | 4 | 3.30.40.10 | |
| Domain | TSP_1 | 3.45e-03 | 63 | 26 | 2 | PF00090 | |
| Domain | Znf_RING/FYVE/PHD | 3.50e-03 | 459 | 26 | 4 | IPR013083 | |
| Domain | TSP1 | 3.67e-03 | 65 | 26 | 2 | SM00209 | |
| Domain | TSP1_rpt | 3.67e-03 | 65 | 26 | 2 | IPR000884 | |
| Domain | TSP1 | 3.67e-03 | 65 | 26 | 2 | PS50092 | |
| Domain | PHD | 4.86e-03 | 75 | 26 | 2 | PF00628 | |
| Domain | Znf_PHD-finger | 5.38e-03 | 79 | 26 | 2 | IPR019787 | |
| Domain | PHD | 6.77e-03 | 89 | 26 | 2 | SM00249 | |
| Domain | Znf_PHD | 7.07e-03 | 91 | 26 | 2 | IPR001965 | |
| Domain | ZF_PHD_2 | 7.68e-03 | 95 | 26 | 2 | PS50016 | |
| Domain | ZF_PHD_1 | 7.84e-03 | 96 | 26 | 2 | PS01359 | |
| Pubmed | KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions. | 5.80e-07 | 2 | 27 | 2 | 28723559 | |
| Pubmed | WDR5 interacts with mixed lineage leukemia (MLL) protein via the histone H3-binding pocket. | 3.48e-06 | 4 | 27 | 2 | 18840606 | |
| Pubmed | 3.48e-06 | 4 | 27 | 2 | 26267306 | ||
| Pubmed | MLL1 is required for PAX7 expression and satellite cell self-renewal in mice. | 3.48e-06 | 4 | 27 | 2 | 31534153 | |
| Pubmed | A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity. | 3.48e-06 | 4 | 27 | 2 | 23129768 | |
| Pubmed | 3.48e-06 | 4 | 27 | 2 | 17166833 | ||
| Pubmed | 3.48e-06 | 4 | 27 | 2 | 25834037 | ||
| Pubmed | Taspase1 orchestrates fetal liver hematopoietic stem cell and vertebrae fates by cleaving TFIIA. | 3.48e-06 | 4 | 27 | 2 | 34156981 | |
| Pubmed | 5.80e-06 | 5 | 27 | 2 | 26320581 | ||
| Pubmed | 5.80e-06 | 5 | 27 | 2 | 25561738 | ||
| Pubmed | MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia. | 5.80e-06 | 5 | 27 | 2 | 28609655 | |
| Pubmed | 7.51e-06 | 49 | 27 | 3 | 34368113 | ||
| Pubmed | 7.98e-06 | 50 | 27 | 3 | 37974198 | ||
| Pubmed | MLL associates specifically with a subset of transcriptionally active target genes. | 8.69e-06 | 6 | 27 | 2 | 16199523 | |
| Pubmed | Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian male germ cell programs. | 8.69e-06 | 6 | 27 | 2 | 24176642 | |
| Pubmed | Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases. | 1.62e-05 | 8 | 27 | 2 | 23130995 | |
| Pubmed | 1.62e-05 | 8 | 27 | 2 | 22266653 | ||
| Pubmed | 2.08e-05 | 9 | 27 | 2 | 22665483 | ||
| Pubmed | Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression. | 2.08e-05 | 9 | 27 | 2 | 16951254 | |
| Pubmed | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. | 2.60e-05 | 10 | 27 | 2 | 29276034 | |
| Pubmed | Members of RTP and REEP gene families influence functional bitter taste receptor expression. | 2.60e-05 | 10 | 27 | 2 | 16720576 | |
| Pubmed | 3.81e-05 | 12 | 27 | 2 | 27563068 | ||
| Pubmed | 4.50e-05 | 13 | 27 | 2 | 24619213 | ||
| Pubmed | 6.92e-05 | 16 | 27 | 2 | 23870121 | ||
| Pubmed | 1.09e-04 | 20 | 27 | 2 | 19047629 | ||
| Pubmed | Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition. | 1.21e-04 | 21 | 27 | 2 | 27626377 | |
| Pubmed | Structural basis for activity regulation of MLL family methyltransferases. | 1.33e-04 | 22 | 27 | 2 | 26886794 | |
| Pubmed | 1.72e-04 | 25 | 27 | 2 | 36343752 | ||
| Pubmed | 1.72e-04 | 25 | 27 | 2 | 25664857 | ||
| Pubmed | TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma. | 2.17e-04 | 28 | 27 | 2 | 29653964 | |
| Pubmed | Rebalancing gene haploinsufficiency in vivo by targeting chromatin. | 2.17e-04 | 28 | 27 | 2 | 27256596 | |
| Pubmed | 3.82e-04 | 183 | 27 | 3 | 36129980 | ||
| Pubmed | 4.45e-04 | 40 | 27 | 2 | 37516964 | ||
| Pubmed | 5.14e-04 | 43 | 27 | 2 | 33472061 | ||
| Pubmed | 5.38e-04 | 44 | 27 | 2 | 24183668 | ||
| GeneFamily | Zinc fingers CXXC-type | 8.42e-05 | 12 | 21 | 2 | 136 | |
| GeneFamily | Zinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family | 7.05e-04 | 34 | 21 | 2 | 487 | |
| GeneFamily | PHD finger proteins | 4.84e-03 | 90 | 21 | 2 | 88 | |
| GeneFamily | ADAM metallopeptidase domain containing|CD molecules | 1.02e-02 | 394 | 21 | 3 | 471 | |
| ToppCell | Hippocampus|World / BrainAtlas - Mouse McCarroll V32 | 3.70e-06 | 176 | 27 | 4 | f120a703f6d2f2d5f55eae1aea2e6382a485828f | |
| ToppCell | Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 5.55e-06 | 195 | 27 | 4 | 19853c654ac64b3ae3bc99841c6cb29c8aaba85c | |
| ToppCell | Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type | 5.55e-06 | 195 | 27 | 4 | d3755929ebbbf5e3afde44281e9056ddb614a291 | |
| ToppCell | COVID-19_Moderate-multiplets|COVID-19_Moderate / disease group, cell group and cell class | 9.44e-05 | 147 | 27 | 3 | baf15c773d7751bc6f64d4974a22738626f2b3ff | |
| ToppCell | COVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type | 9.63e-05 | 148 | 27 | 3 | d6ac5972267254651dfbe16bb4e9a62228093cc7 | |
| ToppCell | COVID-19_Moderate-multiplets|World / disease group, cell group and cell class | 1.13e-04 | 156 | 27 | 3 | afdc025fa75e7926b1cc182c4a33654a2186abb1 | |
| ToppCell | COVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type | 1.19e-04 | 159 | 27 | 3 | 5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d | |
| ToppCell | PND14-Immune-Immune_Myeloid-DC-cDC1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif | 1.30e-04 | 164 | 27 | 3 | 90404b3b6b6a9b88a75cba09baa94c718e577c44 | |
| ToppCell | droplet-Liver-Npc-18m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.40e-04 | 168 | 27 | 3 | 22c89d4eb44573f6301069ec7ca7cbd0dd958403 | |
| ToppCell | droplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.40e-04 | 168 | 27 | 3 | ce5e92a1df3acfa5cd8d5a134e4af231dc592a13 | |
| ToppCell | Severe-CD4+_T_activated|Severe / Disease group and Cell class | 1.63e-04 | 177 | 27 | 3 | a08f170f1143fcdd7d0842a54d9b807a4548f8b7 | |
| ToppCell | Severe-CD4+_T_activated|World / Disease group and Cell class | 1.66e-04 | 178 | 27 | 3 | ef6111238703579a34bd6948bd9d4ca6b7e16063 | |
| ToppCell | 3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.83e-04 | 184 | 27 | 3 | ed7a8e79e5723a5f5a03f542203d9e50bdef5f50 | |
| ToppCell | droplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 1.83e-04 | 184 | 27 | 3 | 1154a5ad7b8512272b7476f949ddac350910bfb7 | |
| ToppCell | 3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.89e-04 | 186 | 27 | 3 | bdd9d3a432aab46e733469b362f0064d35c1ac49 | |
| ToppCell | 3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 1.92e-04 | 187 | 27 | 3 | 9042bd0f57213a51503d9df2e4dce3209b7772d3 | |
| ToppCell | droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.11e-04 | 193 | 27 | 3 | dc92680b4bb9fc26430c92e03adb839c8c3b3b98 | |
| ToppCell | droplet-Pancreas-Endocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.11e-04 | 193 | 27 | 3 | 03678162648bd5b1d65a5450b60c8863edbf95c7 | |
| ToppCell | droplet-Pancreas-Endocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation | 2.11e-04 | 193 | 27 | 3 | 59b8186d0221fba06a16157e9d148399ed801f38 | |
| ToppCell | 5'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.27e-04 | 198 | 27 | 3 | 8d629492d2199de8e036c19e9dacceb9c9e721a0 | |
| ToppCell | 5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.27e-04 | 198 | 27 | 3 | 6e6af8fad09f8e48b3f2ce463d5773b6a69864d1 | |
| ToppCell | 5'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.31e-04 | 199 | 27 | 3 | a5fffe381be1ba7d192b68d1d3937ce47663658e | |
| ToppCell | Transverse-(5)_Dendritic_cell-(51)_cDC1|Transverse / shred on region, Cell_type, and subtype | 2.31e-04 | 199 | 27 | 3 | 52dd1c4cd372f8ee515307a9200e357bb2145888 | |
| ToppCell | Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations | 2.31e-04 | 199 | 27 | 3 | fbec5c034576cb1adaf05f6f97cc5525d19e0c1b | |
| ToppCell | 5'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract | 2.31e-04 | 199 | 27 | 3 | 01c2721bc82cd672e9477029b4a7ecc77e2f1b00 | |
| ToppCell | Transverse-Dendritic_cell-cDC1|Transverse / Region, Cell class and subclass | 2.31e-04 | 199 | 27 | 3 | b68419939d206417158a703f60a374bf8ec5d5a1 | |
| ToppCell | (51)_cDC1|World / shred on Cell_type and subtype | 2.48e-04 | 204 | 27 | 3 | a8cf4180c406674b7541917d1fc6127686ba5f8a | |
| Disease | QRS-T angle | 9.78e-05 | 106 | 25 | 3 | EFO_0020097 | |
| Disease | kidney disease (implicated_via_orthology) | 5.54e-04 | 41 | 25 | 2 | DOID:557 (implicated_via_orthology) | |
| Disease | colitis (biomarker_via_orthology) | 5.81e-04 | 42 | 25 | 2 | DOID:0060180 (biomarker_via_orthology) | |
| Disease | human papilloma virus infection, oropharynx cancer | 9.25e-04 | 53 | 25 | 2 | EFO_0001668, EFO_1001931 | |
| Disease | congenital heart disease (implicated_via_orthology) | 1.56e-03 | 69 | 25 | 2 | DOID:1682 (implicated_via_orthology) | |
| Disease | behavioural disinhibition measurement | 1.84e-03 | 75 | 25 | 2 | EFO_0006946 | |
| Disease | chronic obstructive pulmonary disease | 2.51e-03 | 688 | 25 | 4 | EFO_0000341 | |
| Disease | obsolete_red blood cell distribution width | 4.87e-03 | 1347 | 25 | 5 | EFO_0005192 | |
| Disease | RS-warfarin measurement | 5.25e-03 | 128 | 25 | 2 | EFO_0803325 |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| VVCIWVQQNHPGWTV | 11 | Q9BPW4 | |
| VWTNDQVVHWVQSIG | 1031 | O75335 | |
| QSIWHTACAENWTTQ | 696 | P98073 | |
| VSTQNCWSEACSVHW | 1656 | Q8N6G6 | |
| QHVNHVWPQTSSSWI | 711 | P09848 | |
| EHHSTWAQAQRICTW | 841 | Q9UBG0 | |
| IGQNEWTHVNCAIWS | 1601 | Q9UMN6 | |
| WTHVNCAIWSAEVFE | 1606 | Q9UMN6 | |
| WIWTSKTLQSWQQVC | 521 | Q9ULW2 | |
| QVWQQTVDQRLSSWH | 636 | Q8IW35 | |
| NEWTHVNCALWSAEV | 1896 | Q03164 | |
| AQVALTCTQIWWTTE | 1716 | Q9NYC9 | |
| WRQDHVVDSWQSAVC | 171 | Q70HW3 | |
| SWASAQVQILCHTYW | 61 | Q96DX8 | |
| QVQILCHTYWEHWTS | 66 | Q96DX8 | |
| FNDVVWHVSWSITAN | 261 | P55735 | |
| TNIWTVINHFSVWLA | 86 | Q9NYV8 | |
| TVHWVQAVGWCNNIA | 1171 | O14607 | |
| HLLWVSSQQWVEAVV | 476 | Q7Z333 | |
| ATWCWCTDQVIVQRS | 291 | Q2M3M2 | |
| CLDQEVIISNWHWAT | 56 | P03915 | |
| VIISNWHWATTQTTQ | 61 | P03915 | |
| VTTVSHNWTVWNCTS | 161 | Q8N6D2 | |
| HNWTVWNCTSLLFQT | 166 | Q8N6D2 | |
| IVVSVCTATGAWNWL | 36 | Q8N9A8 | |
| TSHCTWVAAHWTTSQ | 91 | Q96NS8 | |
| CESIAWFVNWINETH | 651 | O15455 | |
| VWAVIISHQQCWAST | 386 | Q9C019 | |
| TCWTLSRYAHWVVSQ | 466 | Q92973 | |
| SWVVEHWSSCKINNE | 1061 | Q9C0I4 | |
| RWNVHCVTTQWFFDS | 256 | Q92547 | |
| STNSHVCLLWAWVHS | 246 | Q9BXU2 |