Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphoric diester hydrolase activity

PLCE1 NAPEPLD

8.22e-049792GO:0008081
GeneOntologyMolecularFunctionphospholipase activity

PLCE1 NAPEPLD

1.13e-0311492GO:0004620
GeneOntologyMolecularFunctionlipase activity

PLCE1 NAPEPLD

1.65e-0313892GO:0016298
MousePhenodelayed eyelid opening

FOXP2 PLAG1

1.13e-043372MP:0001290
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

SS18L1 BCL7A

1.80e-044272M48237
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

SS18L1 BCL7A

9.23e-049572M48268
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_PIWI_INTERACTING_RNAS_PIRNAS

SS18L1 BCL7A

9.62e-049772M48262
PathwayREACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT

SS18L1 BCL7A

1.91e-0313772M48232
PathwayREACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS

SS18L1 BCL7A

2.05e-0314272M48257
Pubmed

An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.

SS18L1 BCL7A

2.41e-05299219279220
Pubmed

Interaction network of human early embryonic transcription factors.

FOXP2 SS18L1 BCL7A

8.18e-053519338297188
Pubmed

The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

SS18L1 BCL7A

9.43e-05579221555454
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TAF9 FOXP2 SS18L1 BCL7A

1.17e-0411169431753913
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

FOXP2 SS18L1

1.23e-04659226655900
InteractionFEV interactions

TAF9 FOXP2 SS18L1 BCL7A

1.21e-0620394int:FEV
InteractionEGR2 interactions

FOXP2 SS18L1 BCL7A

4.86e-0517193int:EGR2
InteractionBICRAL interactions

SS18L1 BCL7A

1.59e-044392int:BICRAL
InteractionHNF4A interactions

TAF9 SS18L1 BCL7A

1.99e-0427593int:HNF4A
InteractionSP7 interactions

TAF9 SS18L1 BCL7A

2.67e-0430493int:SP7
InteractionBICRA interactions

SS18L1 BCL7A

3.86e-046792int:BICRA
InteractionSMARCA2 interactions

TAF9 SS18L1 BCL7A

3.90e-0434693int:SMARCA2
InteractionSS18 interactions

SS18L1 BCL7A

6.65e-048892int:SS18
InteractionBCL7B interactions

SS18L1 BCL7A

7.75e-049592int:BCL7B
InteractionDPF3 interactions

SS18L1 BCL7A

7.75e-049592int:DPF3
InteractionDPF1 interactions

SS18L1 BCL7A

7.75e-049592int:DPF1
InteractionSS18L1 interactions

SS18L1 BCL7A

8.24e-049892int:SS18L1
InteractionSMARCD3 interactions

SS18L1 BCL7A

9.81e-0410792int:SMARCD3
InteractionTAF9B interactions

TAF9 SS18L1

1.00e-0310892int:TAF9B
InteractionDSG4 interactions

FOXP2 FBXL4

1.04e-0311092int:DSG4
InteractionTBR1 interactions

FOXP2 BCL7A

1.09e-0311392int:TBR1
InteractionBRD3 interactions

TAF9 SS18L1 BCL7A

1.10e-0349493int:BRD3
InteractionBCL7C interactions

SS18L1 BCL7A

1.13e-0311592int:BCL7C
InteractionTBXT interactions

SS18L1 BCL7A

1.15e-0311692int:TBXT
InteractionNSD3 interactions

SS18L1 BCL7A

1.17e-0311792int:NSD3
InteractionBRD9 interactions

SS18L1 BCL7A

1.17e-0311792int:BRD9
InteractionVSIG8 interactions

FOXP2 FBXL4

1.21e-0311992int:VSIG8
InteractionETS1 interactions

SS18L1 BCL7A

1.25e-0312192int:ETS1
InteractionBCL7A interactions

SS18L1 BCL7A

1.29e-0312392int:BCL7A
InteractionPAX7 interactions

SS18L1 BCL7A

1.31e-0312492int:PAX7
InteractionPKP3 interactions

FOXP2 FBXL4

1.58e-0313692int:PKP3
InteractionLRRC15 interactions

FOXP2 FBXL4

1.60e-0313792int:LRRC15
InteractionPHF10 interactions

SS18L1 BCL7A

1.65e-0313992int:PHF10
InteractionARID2 interactions

SS18L1 BCL7A

1.99e-0315392int:ARID2
InteractionSELENBP1 interactions

FOXP2 FBXL4

1.99e-0315392int:SELENBP1
InteractionSOX5 interactions

FOXP2 BCL7A

2.23e-0316292int:SOX5
InteractionARID1B interactions

SS18L1 BCL7A

2.65e-0317792int:ARID1B
InteractionDUSP14 interactions

FOXP2 FBXL4

2.77e-0318192int:DUSP14
InteractionSMARCD2 interactions

SS18L1 BCL7A

2.83e-0318392int:SMARCD2
InteractionMYOD1 interactions

SS18L1 BCL7A

3.17e-0319492int:MYOD1
CoexpressionHEVNER_VENTRICULAR_ZONE_AND_UP_NEURON_FATE_COMMITTED_CELLS

SS18L1 BCL7A

1.10e-051592MM410
ToppCellnormal_Pleural_Fluid-B_lymphocytes-Plasma_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

FBXL4 PLCE1

3.03e-04132924e37400ae7375e6986f060234c373194603346f8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

3.51e-04142926469cf82552b39f63e20b841c9eed50de6f58d54
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

3.97e-041519216fc903fc71e25717b9908416f0bcd29c0a65a61
ToppCell3'_v3-bone_marrow-Lymphocytic_B-Pre-B|bone_marrow / Manually curated celltypes from each tissue

PLCE1 BCL7A

4.56e-0416292e088e66aabc307dde5d2b9aa295c34ef68155b1a
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXP2 PLCE1

4.90e-0416892b1d6c35a5ae69c8638afd68c2be5bc9ce6fd2659
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXP2 PLCE1

4.90e-0416892e40a3f85be7e9bb23bfbc1f9cb5e5fc54bb43863
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

5.02e-04170925d5f208682be21ed58320f5fc083a7898f8712da
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLCE1 PLAG1

5.44e-041779244c38e572a9e9678c2dbb3e8b4748e7e28d404b7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 BCL7A

5.50e-0417892dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 BCL7A

5.56e-0417992d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 BCL7A

5.56e-04179922e49b215b71438400aebb483f2c2c08d5e956961
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

5.69e-04181929d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

5.75e-0418292eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLCE1 NAPEPLD

5.81e-04183929c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PLCE1 NAPEPLD

5.81e-04183923c516fe5083f02bad1f464ed284010b4131a833c
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP2 PLCE1

5.94e-04185923a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SS18L1 PLCE1

5.94e-0418592bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP2 PLCE1

5.94e-0418592224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCelldroplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP2 PLCE1

6.07e-04187929c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

6.07e-0418792c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLCE1 NAPEPLD

6.07e-04187926f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP2 PLCE1

6.07e-04187929e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXP2 PLCE1

6.13e-0418892dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLCE1 BCL7A

6.13e-0418892e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXP2 PLCE1

6.13e-04188922ef08313087e91985bcffc46c3798470cdeec49c
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXP2 PLCE1

6.13e-04188921f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL4 PLCE1

6.20e-04189924dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL4 PLCE1

6.20e-04189920d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

6.20e-0418992904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SS18L1 ODR4

6.26e-04190923f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

6.26e-04190921cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

6.26e-041909259bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXP2 PLCE1

6.26e-041909257c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXP2 PLCE1

6.26e-0419092f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCelldroplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXP2 PLCE1

6.26e-0419092a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXP2 PLCE1

6.33e-0419192b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SS18L1 ODR4

6.39e-0419292c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLCE1 BCL7A

6.53e-04194922b61023a602d336ed0de174e9141046173db34e6
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PLCE1 BCL7A

6.53e-0419492f2486b19ac52a48d19f80b38a5536bee3dad745b
ToppCellIPF-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

FOXP2 PLCE1

6.59e-0419592de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCellCOPD-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

FOXP2 PLCE1

6.59e-0419592e91ce548ae7224661ee5d2f2639794a5f69798ee
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FOXP2 NAPEPLD

6.66e-0419692c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellControl-Endothelial-Lymphatic|Endothelial / Disease state, Lineage and Cell class

FOXP2 PLCE1

6.66e-0419692e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCellSepsis-Bac-SEP-Lymphocyte-B-B_intermediate|Bac-SEP / Disease, condition lineage and cell class

PLCE1 BCL7A

6.66e-04196921611920211beb1a3691e3853e0314792a74279a0
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-20|World / Primary Cells by Cluster

PLCE1 NAPEPLD

6.80e-0419892bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate|COVID-19_Mild / Disease, condition lineage and cell class

PLCE1 BCL7A

6.87e-04199921c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

FOXP2 PLAG1

6.87e-0419992399e73d45638848e68edda120316ceff04d98680
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXP2 PLCE1

6.87e-04199924217b9e66c5374461e84bdb893ab650f148286c8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related|6m / Sample Type, Dataset, Time_group, and Cell type.

FOXP2 BCL7A

6.93e-0420092ea1e3eeddbc398ac97863120f7aa3f17569ca12a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-OPC_related-Oligodendrocyte/OPC|6m / Sample Type, Dataset, Time_group, and Cell type.

FOXP2 BCL7A

6.93e-04200924a57f2f2dc6e2402ac4772b5cd38e033a6f1adee
ToppCellmild-B_intermediate|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PLCE1 BCL7A

6.93e-04200928e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

FOXP2 PLAG1

6.93e-0420092c792d1dbbe27ebd60f4770834f30882c1a625be5
DiseaseRussell-Silver syndrome

FOXP2 PLAG1

3.72e-061092C0175693
Diseasefunctional brain measurement

FOXP2 PLCE1

2.71e-048292EFO_0007849
Diseasebody weight

FOXP2 PLAG1 BCL7A

5.39e-03126193EFO_0004338
Diseaselean body mass

PLCE1 PLAG1

5.58e-0337992EFO_0004995
Diseasebirth weight

PLCE1 PLAG1

6.17e-0339992EFO_0004344

Protein segments in the cluster

PeptideGeneStartEntry
EETNTACMSSSMNSQ

ODR4

391

Q5SWX8
ACMSSSMNSQASLDN

ODR4

396

Q5SWX8
ATETISNSSMNQNGM

FOXP2

6

O15409
SNSSMNQNGMSTLSS

FOXP2

11

O15409
MMNTHRAIESNSQTS

FBXL4

31

Q9UKA2
EQNSQSSMEHSMNSS

BCL7A

151

Q4VC05
ITTNMMSSQNTANES

TAF9

226

Q16594
NSSGNTMSASSMFNT

PLCE1

1991

Q9P212
VSMMQQQAATSHYSS

SS18L1

186

O75177
QSMQSSGSAHQMITT

PLAG1

296

Q6DJT9
MDENESNQSLMTSSQ

NAPEPLD

1

Q6IQ20