Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphorbol ester receptor activity

UNC13B UNC13C

6.79e-0521652GO:0001565
GeneOntologyMolecularFunctionnon-kinase phorbol ester receptor activity

UNC13B UNC13C

6.79e-0521652GO:0001566
GeneOntologyCellularComponentNoRC complex

SMARCA5 BAZ2A

6.04e-0521632GO:0090536
GeneOntologyCellularComponenteukaryotic translation initiation factor 4F complex

EIF4B EIF4G1 EIF4G3

1.26e-04131633GO:0016281
GeneOntologyCellularComponentRNA cap binding complex

EIF4B EIF4G1 EIF4G3

2.92e-04171633GO:0034518
DomainMA3

CWC22 EIF4G1 EIF4G3

1.35e-0561663SM00544
DomainMA3

CWC22 EIF4G1 EIF4G3

1.35e-0561663PF02847
DomainInitiation_fac_eIF4g_MI

CWC22 EIF4G1 EIF4G3

1.35e-0561663IPR003891
DomainMI

CWC22 EIF4G1 EIF4G3

1.35e-0561663PS51366
DomainChromo_domain

CBX6 CHD5 CHD6 CBX8

5.57e-05241664IPR023780
DomainChromo

CBX6 CHD5 CHD6 CBX8

7.72e-05261664PF00385
DomainGCM

GCM2 GCM1

7.85e-0521662PS50807
DomainGCM

GCM2 GCM1

7.85e-0521662PF03615
DomainTscrpt_reg_GCM

GCM2 GCM1

7.85e-0521662IPR003902
DomainGCM_motif

GCM2 GCM1

7.85e-0521662PD014393
DomainMIF4G

CWC22 EIF4G1 EIF4G3

7.90e-05101663SM00543
DomainMIF4G

CWC22 EIF4G1 EIF4G3

7.90e-05101663PF02854
DomainMIF4G-like_typ-3

CWC22 EIF4G1 EIF4G3

7.90e-05101663IPR003890
DomainCHROMO_1

CBX6 CHD5 CHD6 CBX8

1.04e-04281664PS00598
DomainCHROMO_2

CBX6 CHD5 CHD6 CBX8

1.04e-04281664PS50013
DomainChromodomain-like

CBX6 CHD5 CHD6 CBX8

1.78e-04321664IPR016197
DomainChromo/shadow_dom

CBX6 CHD5 CHD6 CBX8

2.01e-04331664IPR000953
DomainCHROMO

CBX6 CHD5 CHD6 CBX8

2.01e-04331664SM00298
DomainHRDC

EXOSC10 BLM

2.34e-0431662SM00341
DomainHRDC

EXOSC10 BLM

2.34e-0431662PS50967
DomainHRDC

EXOSC10 BLM

2.34e-0431662PF00570
DomainUnc-13

UNC13B UNC13C

2.34e-0431662IPR027080
DomainFN3

MYOM1 KIAA0319L OBSL1 FNDC1 PTPRF PTPRO IL23R EPHB1

2.54e-041851668SM00060
DomainDNA/RNA_helicase_DEAH_CS

SMARCA5 BLM CHD5 CHD6

2.54e-04351664IPR002464
Domain-

CWC22 EIF4G1 EIF4G3

2.90e-041516631.25.40.180
DomainMIF4-like

CWC22 EIF4G1 EIF4G3

2.90e-04151663IPR016021
DomainDEAH_ATP_HELICASE

SMARCA5 BLM CHD5 CHD6

3.51e-04381664PS00690
DomainHRDC_dom

EXOSC10 BLM

4.66e-0441662IPR002121
Domain-

PCSK5 ALLC F5 NRP2 EPHB1

4.82e-047316652.60.120.260
DomainFN3_dom

MYOM1 KIAA0319L OBSL1 FNDC1 PTPRF PTPRO IL23R EPHB1

5.73e-042091668IPR003961
Domainfn3

MYOM1 OBSL1 FNDC1 PTPRF PTPRO IL23R EPHB1

6.21e-041621667PF00041
DomainFerI

MYOF OTOF

7.72e-0451662SM01202
DomainFerB

MYOF OTOF

7.72e-0451662SM01201
DomainMunc13_dom-2

UNC13B UNC13C

7.72e-0451662IPR014772
DomainFerlin_B-domain

MYOF OTOF

7.72e-0451662IPR012561
DomainFerlin_C

MYOF OTOF

7.72e-0451662PF16165
DomainFerlin_C

MYOF OTOF

7.72e-0451662IPR032362
DomainFerIin_dom

MYOF OTOF

7.72e-0451662IPR012968
DomainMHD2

UNC13B UNC13C

7.72e-0451662PS51259
DomainFerI

MYOF OTOF

7.72e-0451662PF08151
DomainFerB

MYOF OTOF

7.72e-0451662PF08150
DomainMunc13_subgr_dom-2

UNC13B UNC13C

7.72e-0451662IPR019558
DomainHRDC-like

EXOSC10 BLM

7.72e-0451662IPR010997
DomainCBX7_C

CBX6 CBX8

7.72e-0451662PF17218
DomainMembr_traf_MHD

UNC13B UNC13C

7.72e-0451662PF10540
DomainCBX7_C

CBX6 CBX8

7.72e-0451662IPR033773
DomainDUF1041

UNC13B UNC13C

7.72e-0451662SM01145
DomainC2

UNC13B PCLO RAB11FIP2 MYOF OTOF UNC13C

1.13e-031311666PF00168
DomainC2

UNC13B PCLO RAB11FIP2 MYOF OTOF UNC13C

1.42e-031371666SM00239
DomainGalactose-bd-like

PCSK5 ALLC F5 NRP2 EPHB1

1.52e-03941665IPR008979
Domain-

OCRL SYNJ1 EEPD1

1.54e-032616633.60.10.10
DomainExo_endo_phos

OCRL SYNJ1 EEPD1

1.54e-03261663PF03372
DomainMunc13_1

UNC13B UNC13C

1.60e-0371662IPR014770
DomaineIF5C

EIF4G1 EIF4G3

1.60e-0371662SM00515
DomainMHD1

UNC13B UNC13C

1.60e-0371662PS51258
DomainDUF1041

UNC13B UNC13C

1.60e-0371662PF06292
DomainCAPS_dom

UNC13B UNC13C

1.60e-0371662IPR010439
DomainW2

EIF4G1 EIF4G3

1.60e-0371662PF02020
DomainW2

EIF4G1 EIF4G3

1.60e-0371662PS51363
DomainW2_domain

EIF4G1 EIF4G3

1.60e-0371662IPR003307
DomainC2

UNC13B PCLO RAB11FIP2 MYOF OTOF UNC13C

1.70e-031421666PS50004
Domain-

KLHL28 KLHL36 KLHL18

1.72e-032716632.130.10.80
DomainEndo/exonuclease/phosphatase

OCRL SYNJ1 EEPD1

1.72e-03271663IPR005135
DomainFN3

MYOM1 OBSL1 FNDC1 PTPRF PTPRO IL23R EPHB1

2.05e-031991667PS50853
Domain-

UNC13B PCLO RAB11FIP2 MYOF OTOF UNC13C

2.10e-0314816662.60.40.150
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

AKAP6 CYLD PRUNE2 CASP8AP2 DNAJC16 SYNE1 KIAA0232 OBSL1 MYOF ALMS1 SYNJ1 CHD5 CHD6 STK38L

5.38e-122251671412168954
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CYLD ARHGAP32 DPYSL3 RAP1GAP HIVEP1 KIAA0232 RAB11FIP2 TRIP12 LYST DENND2B STK4 VPS13D KCNQ5 ALMS1 BAIAP2L1 SYNJ1 STARD9 EIF4B EIF4G1 EIF4G3 DCLK1

1.22e-098611672136931259
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CYLD EPS8 ARHGAP32 DPYSL3 KIAA0232 KIAA0319L CASP9 OCRL PPP2R3A GANAB ALMS1 BAIAP2L1 SYNJ1 EIF4B TBC1D23 MGA CBX8

8.60e-078531671728718761
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PRUNE2 ARHGAP32 RNF169 RAP1GAP MYSM1 MYOF VPS13D ALMS1 EEPD1 EIF5B MGA KLHL18 TMEM63A

8.60e-074931671315368895
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

HNRNPDL EXOSC10 RNF169 SMARCA5 HIVEP1 DLGAP5 CWC22 TRIP12 PRPF40A BLM TARDBP BAZ2A EIF4B EIF4G1 EIF5B MGA CBX8

3.86e-069541671736373674
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

UNC13B CYLD UBR2 DNAJC16 SYNE1 KIAA0232 OBSL1 GANAB BAZ2A STARD9 CHD6

4.86e-064071671112693553
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

HNRNPDL CYLD EXOSC10 IQGAP2 DNAJC16 KIAA0319L OCRL TRIP12 BLM TARDBP FAT1 PPP2R3A BAIAP2L1 EIF4G3 MGA

5.73e-067771671535844135
Pubmed

Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.

UNC13B OTOF UNC13C

5.98e-068167325609709
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

HNRNPDL EXOSC10 SMARCA5 SYNE1 ARPC1A OBSL1 TRIP12 F5 PRPF40A BLMH TARDBP GANAB PTPRF EIF4G1 EIF5B NUP188 MGA

9.74e-0610241671724711643
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

UNC13B HIVEP1 MYOM1 TRIP12 F5 FAT1 OTOF EIF4B EIF4G1 SERPING1

1.07e-053611671026167880
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

RNF169 REPS1 MAMLD1 TACC2 PRPF40A BLM BLMH TARDBP EIF4B EIF4G1 MGA

1.10e-054441671134795231
Pubmed

Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.

SMARCA5 ARPC1A CWC22 TRIP12 PRPF40A GANAB CEP78 BAIAP2L1 CBX6 EIF5B MGA CBX8

1.14e-055331671230554943
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

AKAP6 PRUNE2 UBR2 ALMS1 BAZ2A DCLK1

1.15e-0510416769205841
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DPYSL3 EXOSC10 SMARCA5 REPS1 DLGAP5 TACC2 OCRL PRPF40A STK4 TARDBP ALMS1 SYNJ1 BAZ2A EIF4B EIF5B EIF4G3

1.23e-059341671633916271
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

HNRNPDL SYNE1 GATM TACC2 CWC22 MAD2L1BP CRY1 BLM BLMH STK4 TARDBP GANAB NDEL1 CEP78 EIF4B TUBGCP3 EIF4G1 NUP188

1.24e-0511551671820360068
Pubmed

The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation.

CYLD MAPK14 IL1R1

1.27e-0510167322000287
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

EXOSC10 SMARCA5 DNAJC16 SYNE1 NEB TRIP12 PRPF40A OTOF

1.88e-05234167836243803
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

EPS8 DPP6 ARHGAP32 DPYSL3 RAP1GAP IQGAP2 SYNE1 PCLO ARPC1A PRPF40A STK4 NDEL1 SYNJ1 NTM EIF4B EIF4G1 EIF4G3 DCLK1 CACNA2D3 DNAH11

1.92e-0514311672037142655
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

HNRNPDL EPS8 SMARCA5 HIP1 ARPC1A CWC22 TRIP12 F5 PRPF40A MYOF EIF4G1 EIF5B NUP188

2.00e-056601671332780723
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 HNRNPDL CYLD EXOSC10 TTLL3 IQGAP2 DLGAP5 TACC2 TRIP12 SBNO2 ADH5 TARDBP SYNJ1 EIF4B NUP188 MGA DCLK1

2.02e-0510841671711544199
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

ABCC3 EPS8 ARHGAP32 IQGAP2 DNAJC16 KIAA0319L MTMR10 BLMH FRMD4A FAT1 PTPRF BAIAP2L1

2.16e-055691671230639242
Pubmed

Identification and characterization of novel parathyroid-specific transcription factor Glial Cells Missing Homolog B (GCMB) mutations in eight families with autosomal recessive hypoparathyroidism.

GCM2 GCM1

2.29e-052167220190276
Pubmed

Ferlin Overview: From Membrane to Cancer Biology.

MYOF OTOF

2.29e-052167231443490
Pubmed

Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions.

EIF4G1 EIF4G3

2.29e-052167231999954
Pubmed

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation.

EIF4G1 EIF4G3

2.29e-052167210872469
Pubmed

The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription.

SMARCA5 BAZ2A

2.29e-052167212368916
Pubmed

Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.

UNC13B UNC13C

2.29e-052167222674279
Pubmed

Recognition of tandem PxxP motifs as a unique Src homology 3-binding mode triggers pathogen-driven actin assembly.

EPS8 BAIAP2L1

2.29e-052167221098279
Pubmed

Intergenic transcripts regulate the epigenetic state of rRNA genes.

SMARCA5 BAZ2A

2.29e-052167216678107
Pubmed

The gcm-motif: a novel DNA-binding motif conserved in Drosophila and mammals.

GCM2 GCM1

2.29e-05216728962155
Pubmed

The potential to induce glial differentiation is conserved between Drosophila and mammalian glial cells missing genes.

GCM2 GCM1

2.29e-052167214573516
Pubmed

The GCM domain is a Zn-coordinating DNA-binding domain.

GCM2 GCM1

2.29e-052167212297286
Pubmed

GSNOR negatively regulates the NLRP3 inflammasome via S-nitrosation of MAPK14.

ADH5 MAPK14

2.29e-052167238570588
Pubmed

Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism.

MAPK14 IL1R1

2.29e-052167229601781
Pubmed

Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis.

TARDBP NUP188

2.29e-052167231527135
Pubmed

A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.

DPYSL3 RNF169 DLGAP5 EIF4B EIF4G1 EIF4G3

2.37e-05118167630979931
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

HNRNPDL RNF169 SMARCA5 HIVEP1 DLGAP5 TRIP12 PRPF40A BLM MYOF BAZ2A EIF4B ASPH EIF4G1 EIF5B

2.44e-057741671415302935
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

UNC13B PCSK5 ABCC3 HIP1 REPS1 KIAA0319L LYST SBNO2 MYOF FAT1 PTPRF SYNJ1 KLHL36 CHD5 EIF4G1 ZNF398 NUP188

2.57e-0511051671735748872
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 EXOSC10 HIVEP1 REPS1 MYOM1 SYNE1 NEB ALMS1 EIF4B TUBGCP3 MGA

3.10e-054971671123414517
Pubmed

Functional proteomics mapping of a human signaling pathway.

HIVEP1 CYP11A1 BCAT1 TRIP12 DENND2B PRPF40A MTMR10 PTPRF EIF4G1 PEX19 CHD6 MGA

3.13e-055911671215231748
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

HNRNPDL EXOSC10 SMARCA5 SAMD9 ARPC1A CWC22 TRIP12 F5 TARDBP PTPN2 MYOF BAIAP2L1 CHD5 EIF4B ASPH EIF4G1 EIF5B CBX8

3.76e-0512571671836526897
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

RNF169 SMARCA5 HIVEP1 DLGAP5 TRIP12 MYSM1 BLM BAZ2A CHD5 CHD6 MGA CBX8

4.11e-056081671236089195
Pubmed

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.

PCLO CBX6 MGA CBX8

4.52e-0541167422325352
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

UBR2 ARHGAP32 DPYSL3 RNF169 MTMR10 ADH5 BLM BLMH TARDBP PTPN2 PPP2R3A MAPK14 GANAB PTPRF PEX19 CBX8

4.97e-0510491671627880917
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 UNC13B CYLD RAP1GAP REPS1 SYNE1 KIAA0319L OBSL1 GATM TRIP12 MTMR10 SYNJ1 OTOF EIF4G1 CHD6 TBC1D23 EIF4G3 DCLK1

4.99e-0512851671835914814
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

AKAP6 UNC13B CASP8AP2 HIP1 RAP1GAP TTLL3 NEB SBNO2 BLM FRMD4A FAT1 NDEL1 SYNJ1 PUS10 EIF4B TUBGCP3 ANKRD30A ZNF561

5.40e-0512931671815342556
Pubmed

Network organization of the human autophagy system.

IQGAP2 OBSL1 STK4 MAPK14 GANAB CEP78 BAIAP2L1 EIF4B ASPH EIF5B

5.42e-054371671020562859
Pubmed

Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.

PTPN2 PTPRF IL1R1

5.82e-051616738875997
Pubmed

Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E.

EIF4G1 EIF4G3

6.85e-053167220212144
Pubmed

Impaired binding of standard initiation factors eIF3b, eIF4G and eIF4B to domain V of the live-attenuated coxsackievirus B3 Sabin3-like IRES--alternatives for 5'UTR-related cardiovirulence mechanisms.

EIF4B EIF4G1

6.85e-053167224063684
Pubmed

The C2 domains of otoferlin, dysferlin, and myoferlin alter the packing of lipid bilayers.

MYOF OTOF

6.85e-053167223859474
Pubmed

Confirmation of three inflammatory bowel disease susceptibility loci in a Chinese cohort.

PTPN2 IL23R

6.85e-053167222426692
Pubmed

Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.

UNC13B UNC13C

6.85e-053167233105896
Pubmed

A newly identified N-terminal amino acid sequence of human eIF4G binds poly(A)-binding protein and functions in poly(A)-dependent translation.

EIF4G1 EIF4G3

6.85e-05316729857202
Pubmed

Duplex unwinding and ATPase activities of the DEAD-box helicase eIF4A are coupled by eIF4G and eIF4B.

EIF4B EIF4G1

6.85e-053167221840318
Pubmed

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.

MYOM1 OBSL1

6.85e-053167227989621
Pubmed

Single cell RNA analysis of the left-right organizer transcriptome reveals potential novel heterotaxy genes.

TTLL3 SYNE1

6.85e-053167237393374
Pubmed

FerA is a Membrane-Associating Four-Helix Bundle Domain in the Ferlin Family of Membrane-Fusion Proteins.

MYOF OTOF

6.85e-053167230026467
Pubmed

The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.

UNC13B UNC13C

6.85e-053167223658173
Pubmed

KAT5 silencing induces apoptosis of GBC-SD cells through p38MAPK-mediated upregulation of cleaved Casp9.

CASP9 MAPK14

6.85e-053167224427328
Pubmed

Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing.

GCM2 GCM1

6.85e-05316729770492
Pubmed

Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.

UNC13B UNC13C

6.85e-053167222966208
Pubmed

Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.

UNC13B UNC13C

6.85e-053167215988013
Pubmed

Murine Gcm1 gene is expressed in a subset of placental trophoblast cells.

GCM2 GCM1

6.85e-053167210213386
Pubmed

NoRC--a novel member of mammalian ISWI-containing chromatin remodeling machines.

SMARCA5 BAZ2A

6.85e-053167211532953
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

HNRNPDL SMARCA5 IQGAP2 SYNE1 PCLO FAM47B NEB TRIP12 LYST TARDBP STARD9 CHD5 EIF4B EIF4G1 ANKRD30A EIF5B CHD6 EIF4G3 IL1R1

6.90e-0514421671935575683
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

EXOSC10 SMARCA5 SYNE1 CWC22 TRIP12 ZC3H6 PRPF40A BLM TARDBP GANAB PTPRO TUBGCP3 EIF4G1 EIF5B CHD6 CBX8

7.14e-0510821671638697112
Pubmed

PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.

CYLD ALMS1 EIF4B EIF4G1

9.18e-0549167431762063
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

SYNE1 NEB BLM NUP188 ZNF287 DNAH11

9.74e-05152167634299191
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CASP8AP2 FRMD4A STARD9 CHD5 ZNF398 CHD6

1.01e-04153167610718198
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

HNRNPDL USE1 SYNE1 NADK2 PCLO OBSL1 TACC2 OCRL ATL1 BLM PTPN2 VPS13D GANAB ALMS1 BAZ2A PEX19 ACSF3 NUP188 HCCS

1.11e-0414961671932877691
Pubmed

A human MAP kinase interactome.

CASP8AP2 ARHGAP32 HIVEP1 SYNE1 KIAA0232 NEB MAPK14 NDEL1 CHD6 MGA

1.30e-044861671020936779
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ARHGAP32 SYNE1 EIF5B KLHL18 TMEM63A

1.31e-0410116759872452
Pubmed

Molecular genetics of successful smoking cessation: convergent genome-wide association study results.

DPP6 TACC2 PTPN2 UNC13C CACNA2D3

1.31e-04101167518519826
Pubmed

NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis.

STK4 STK38L

1.37e-044167219062280
Pubmed

Gene Polymorphisms of NOD2, IL23R, PTPN2 and ATG16L1 in Patients with Crohn's Disease: On the Way to Personalized Medicine?

PTPN2 IL23R

1.37e-044167234198814
Pubmed

The NoRC complex mediates the heterochromatin formation and stability of silent rRNA genes and centromeric repeats.

SMARCA5 BAZ2A

1.37e-044167220168299
Pubmed

BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase.

SMARCA5 BAZ2A

1.37e-044167226100909
Pubmed

The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription.

SMARCA5 BAZ2A

1.37e-044167212198165
Pubmed

Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2.

UBR2 MAPK14

1.37e-044167223568773
Pubmed

Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F.

EIF4G1 EIF4G3

1.37e-044167221191102
Pubmed

Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2.

EIF4B EIF4G1

1.37e-044167216281055
Pubmed

Exip, a splicing variant of p38alpha, participates in interleukin-1 receptor proximal complex and downregulates NF-kappaB pathway.

MAPK14 IL1R1

1.37e-044167215388348
Pubmed

Enterohaemorrhagic Escherichia coli exploits a tryptophan switch to hijack host f-actin assembly.

EPS8 BAIAP2L1

1.37e-044167222921828
Pubmed

Hematopoietic stem cell quiescence and function are controlled by the CYLD-TRAF2-p38MAPK pathway.

CYLD MAPK14

1.37e-044167225824820
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DNAJC16 RAB11FIP2 SBNO2 TLL2 STK38L

1.38e-04102167510231032
Pubmed

An investigation into the human serum "interactome".

KIAA0232 OBSL1 APOC3 CFB JARID2 SERPING1

1.38e-04162167615174051
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

HNRNPDL DPYSL3 EXOSC10 IQGAP2 PRPF40A ADH5 BLMH TARDBP GANAB EIF4B EIF4G1 PEX19 EIF5B EIF4G3 STK38L TALDO1

1.42e-0411491671635446349
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

SMARCA5 CWC22 TRIP12 BAZ2A CHD5

1.44e-04103167532744500
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

HNRNPDL UBR2 EXOSC10 SMARCA5 BLM GANAB ALMS1 EIF4G1 EIF5B TALDO1

1.48e-044941671026831064
Pubmed

Telencephalic embryonic subtractive sequences: a unique collection of neurodevelopmental genes.

DPYSL3 SMARCA5 CWC22 ATL1 ZNF561 DCLK1

1.53e-04165167616107646
Pubmed

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

RAP1GAP VPS13D CHD5 TMEM63A

1.55e-045616749455484
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

SMARCA5 IQGAP2 PCLO GATM TRIP12 ATL1 TARDBP EIF4B EIF5B EIF4G3

1.58e-044981671036634849
Pubmed

Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.

SMARCA5 CBX6 MGA CBX8

1.66e-0457167417296600
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

OBSL1 TRIP12 FRMD4A CHD6 MGA

1.88e-04109167533554859
Pubmed

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth.

NDEL1 KCNQ5

2.27e-045167212506198
Pubmed

Deubiquitinase OTUD6B Isoforms Are Important Regulators of Growth and Proliferation.

EIF4B EIF4G1

2.27e-045167227864334
Pubmed

Capturing genes encoding membrane and secreted proteins important for mouse development.

FAT1 PTPRF

2.27e-04516727604039
Pubmed

AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation.

CRY1 EIF4G1

2.27e-045167224423872
Pubmed

Regulation of translation initiation in eukaryotes: mechanisms and biological targets.

EIF4G1 EIF4G3

2.27e-045167219239892
InteractionYWHAH interactions

CYLD ARHGAP32 DPYSL3 RAP1GAP HIVEP1 KIAA0232 RAB11FIP2 CWC22 TRIP12 LYST DENND2B MTMR10 CRY1 STK4 FRMD4A VPS13D KCNQ5 ALMS1 BAIAP2L1 SYNJ1 STARD9 EIF4B EIF4G1 EIF4G3 DCLK1

3.95e-06110216625int:YWHAH
InteractionYWHAG interactions

CYLD ARHGAP32 DPYSL3 RAP1GAP HIVEP1 KIAA0232 RAB11FIP2 CWC22 TRIP12 LYST DENND2B PRPF40A STK4 FRMD4A VPS13D NDEL1 KCNQ5 ALMS1 CEP78 BAIAP2L1 SYNJ1 STARD9 EIF4B EIF4G1 EIF4G3 DCLK1

1.13e-05124816626int:YWHAG
GeneFamilyUNC13 homologs

UNC13B UNC13C

1.88e-0441022836
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

MYOM1 OBSL1 ADAMTSL3 PTPRF NTM IL1R1

3.02e-041611026593
GeneFamilyFerlin family

MYOF OTOF

4.66e-0461022828
GeneFamilyChromobox family

CBX6 CBX8

8.63e-0481022976
GeneFamilyKelch like|BTB domain containing

KLHL28 KLHL36 KLHL18

1.71e-03421023617
GeneFamilyFibronectin type III domain containing

MYOM1 FNDC1 PTPRF PTPRO EPHB1

2.13e-031601025555
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

SMARCA5 MYSM1 CHD6

3.33e-03531023532
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

HNRNPDL UBR2 EPS8 SMARCA5 HIVEP1 DLGAP5 MAMLD1 TRIP12 DENND2B AZIN1 CRY1 BLM JARID2 PTPN2 MYOF FAT1 PPP2R3A MAPK14 TUBGCP3 EIF4G3 IL1R1

1.36e-0785616721M4500
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

HNRNPDL UBR2 EPS8 HIVEP1 MAMLD1 TRIP12 CRY1 BLM JARID2 PTPN2 FAT1 PPP2R3A TUBGCP3 EIF4G3

1.88e-0646616714M13522
CoexpressionIGARASHI_ATF4_TARGETS_DN

RAP1GAP KIAA0232 ARPC1A BCAT1 TRIP12 ASPH PEX19

3.19e-06981677M4779
CoexpressionGSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP

ARHGAP32 HIVEP1 BCAT1 PIWIL4 TACC2 NEB FRMD4A EIF5B HCCS

5.57e-061991679M7852
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

PRUNE2 DPP6 TACC2 TRIP12 DENND2B KCNQ5 PDILT ZNF420 OSBP2

5.80e-062001679M9186
CoexpressionGSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN

SYNE1 IFI44 ZBP1 MYOF PTPRO EEPD1 ASPH TALDO1

1.88e-051771678M7632
CoexpressionBENPORATH_NANOG_TARGETS

CYLD DPYSL3 NAALAD2 DNAJC16 DLGAP5 OBSL1 CASP9 BCAT1 JARID2 PTPN2 FAT1 PPP2R3A MAPK14 ALG9 EIF4B ZNF398 TALDO1 KLHL18 TMEM63A

1.88e-0598816719M6616
CoexpressionGSE42724_NAIVE_BCELL_VS_PLASMABLAST_UP

RTP1 SAMD9 IFI44 MAD2L1BP CFB ZBP1 OTOF SERPING1

4.03e-051971678M9797
CoexpressionGSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP

BCAT1 HPSE GASK1B NRP2 MYOF ASPH STK38L TALDO1

4.03e-051971678M8672
CoexpressionGSE2585_THYMIC_MACROPHAGE_VS_MTEC_DN

AKAP6 KLHL28 CASP9 APOC3 NEB PEX19 CACNA2D3 TDRD12

4.18e-051981678M6280
CoexpressionGSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN

SYNE1 CASP9 BCAT1 CHRNA2 PPP2R3A TUBGCP3 IL1R1 TMEM63A

4.33e-051991678M8415
CoexpressionGSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_UP

HNRNPDL MAMLD1 NDEL1 NUP188 EIF4G3 IL1R1 MGA HCCS

4.49e-052001678M8305
CoexpressionGSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN

CASP8AP2 EPS8 SMARCA5 IQGAP2 GATM AZIN1 PTPN2 NUP188

4.49e-052001678M8854
CoexpressionGSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP

SMARCA5 CYP11A1 ARPC1A HPSE STARD9 PUS10 PEX19 HCCS

4.49e-052001678M6542
CoexpressionTENEDINI_MEGAKARYOCYTE_MARKERS

CASP9 JARID2 MAPK14 IL1R1 RASGRP2

4.77e-05621675M6752
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

DPP6 IQGAP2 NADK2 OBSL1 GATM F5 DENND2B GASK1B FAT1 IQCA1 EEPD1 DCLK1 TMEM63A

8.43e-0557416713M39056
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA

DPP6 DPYSL3 THSD7B NEB LYST PPP2R3A SYNJ1 PTPRO NTM EEPD1 CHD5 DCLK1

1.03e-0450616712M39067
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ACTC_POS_SMC_CELL

PRUNE2 IQGAP2 CASP9 TACC2 ATL1 MAPK14 PTPRF CBX6 KLHL36 NTM EEPD1 STK38L DCLK1

1.09e-0458916713M45662
CoexpressionWANG_SMARCE1_TARGETS_UP

CYLD DPYSL3 KLHL28 IQGAP2 BCAT1 DENND2B FNDC1 TLL2 IL1R1

1.19e-042941679M1804
CoexpressionTOMLINS_PROSTATE_CANCER_DN

CYLD GATM DENND2B MYOF

1.21e-04401674M11504
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2B

DPP6 IQGAP2 NADK2 IFI44 OBSL1 GATM DENND2B FAT1 IQCA1 EEPD1 CHD5

1.25e-0443916711M39054
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

AKAP6 DPP6 IQGAP2 NADK2 OBSL1 GATM DENND2B GASK1B FAT1 IQCA1 EEPD1 DCLK1 EPHB1

1.31e-0460016713M39055
CoexpressionBENPORATH_NOS_TARGETS

DPYSL3 NAALAD2 OBSL1 JARID2 PTPN2 PPP2R3A TALDO1

1.56e-041791677M14573
CoexpressionIKEDA_MIR133_TARGETS_UP

CYLD PTPRO ASPH EIF4G3

1.77e-04441674M2377
CoexpressionFRANCO_BLOOD_SANOFI_PASTEUR_SA_INACTIVATED_INFLUENZA_VACCINE_CORRELATED_WITH_ANTIBODY_RESPONSE_AGE_18_40YO_1DY_POSITIVE

IFI44 SBNO2 ZBP1 MYOF OTOF PTPRO

1.82e-041291676M41110
CoexpressionIKEDA_MIR133_TARGETS_UP

CYLD PTPRO ASPH EIF4G3

1.93e-04451674MM929
CoexpressionQUEREC_PBMC_YF_17D_VACCINE_AGE_18_45YO_7DY_UP

SAMD9 IFI44 MYOF SERPING1

2.11e-04461674M41048
CoexpressionQUEREC_PBMC_YF_17D_VACCINE_AGE_18_45YO_3DY_UP

SAMD9 IFI44 MYOF SERPING1

2.11e-04461674M41047
CoexpressionLASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN

ARHGAP32 EXOSC10 RNF169 NAALAD2 DNAJC16 RAB11FIP2 KIAA0319L CASP9 MYSM1 TARDBP VPS13D PTPRF ALG9 CHD5 EIF4G3

2.14e-0480716715M14594
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

AKAP6 CYLD DPP6 DPYSL3 DNAJC16 PCLO OCRL NEB LYST ATL1 NRP2 PPP2R3A SYNJ1 PTPRO NTM CHD5 DCLK1 EPHB1

2.57e-04110616718M39071
CoexpressionGSE1112_OT1_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN

REPS1 GCM2 MAMLD1 FAM47B TRIP12 MGA DCLK1

2.63e-041951677M6142
CoexpressionGSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN

SAMD9 IFI44 GCM1 PIWIL4 CFB ZBP1 SERPING1

2.71e-041961677M4267
CoexpressionGSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN

SLC17A3 BCAT1 CWC22 CRY1 ASPH ZNF420 TDRD12

2.89e-041981677M5084
CoexpressionGSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_DN

ALLC CEL GCM1 ZBP1 NTM NUP188 DCLK1

2.89e-041981677M7620
CoexpressionGSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP

KIAA0232 OBSL1 ZBP1 CBX6 KLHL36 TALDO1 ZNF287

2.89e-041981677M5790
CoexpressionGSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN

CYLD ARHGAP32 DNAJC16 LYST PTPN2 BAZ2A KLHL18

2.98e-041991677M9418
CoexpressionGSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN

BCAT1 TRIP12 LYST NDEL1 PTPRF EIF4G3 MGA

2.98e-041991677M4567
CoexpressionGSE29949_MICROGLIA_BRAIN_VS_CD8_POS_DC_SPLEEN_UP

HIVEP1 GATM VPS13D PTPRO TLL2 EIF4G3 STK38L

2.98e-041991677M8396
CoexpressionGSE29949_MICROGLIA_VS_DC_BRAIN_DN

NAALAD2 ARPC1A MAMLD1 OCRL NEB PTPN2 SERPING1

2.98e-041991677M8405
CoexpressionGSE17721_CTRL_VS_CPG_24H_BMDC_DN

SLC17A3 ZBP1 PTPN2 PPP2R3A TLL2 PEX19 NUP188

2.98e-041991677M3772
CoexpressionGSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_DN

EPS8 IQGAP2 NRP2 CD84 ASPH GRHL3 DISP1

2.98e-041991677M8736
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN

ARHGAP32 PIWIL4 LYST CRY1 JARID2 EIF4G3 DISP1

2.98e-041991677M9236
CoexpressionGSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN

TTLL3 RAB11FIP2 HPSE MYSM1 SBNO2 CHD6 RASGRP2

3.07e-042001677M9459
CoexpressionGSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_DN

SMARCA5 HIP1 ZBP1 JARID2 PTPN2 MRNIP TBC1D23

3.07e-042001677M5808
CoexpressionGSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN

CYLD ALLC IFI44 CFB SBNO2 MYOF SERPING1

3.07e-042001677M3405
CoexpressionGSE1432_1H_VS_24H_IFNG_MICROGLIA_DN

CYLD UBR2 IFI44 CFB MYOF TUBGCP3 SERPING1

3.07e-042001677M3414
CoexpressionGSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP

TTLL3 TRIP12 PRPF40A BLMH TARDBP SYNJ1 ALG9

3.07e-042001677M9889
CoexpressionGSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN

CYLD ABCC3 RAP1GAP TAPT1 MYOF CBX6 TBC1D23

3.07e-042001677M7230
CoexpressionGSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN

BCAT1 HPSE GASK1B NRP2 MYOF ASPH TALDO1

3.07e-042001677M8682
CoexpressionGSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_DN

ABCC3 GATM CHRNA2 MAD2L1BP BLMH FRMD4A RWDD4

3.07e-042001677M6457
CoexpressionGSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN

IFI44 PIWIL4 HPSE ZBP1 OTOF SERPING1 KLHL18

3.07e-042001677M5139
CoexpressionGSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN

IFI44 BCAT1 SBNO2 STK4 MYOF SERPING1 TALDO1

3.07e-042001677M5228
CoexpressionGSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_DN

RTP1 HIP1 USE1 SYNE1 ZC3H6 CD84

3.18e-041431676M2956
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

UNC13B PRUNE2 PCSK5 HIP1 ZC3H6 FRMD4A BAZ2A EIF5B CHD6 TMEM63A

3.60e-0441716710M39224
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_500

SMARCA5 KLHL28 MYOM1 BCAT1 THSD7B ZC3H6 PRPF40A NRP2 KCNQ5 ADAMTS15 ZNF420 GRHL3 RWDD4 EPHB1

5.73e-0642216514DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_500
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_500

CYLD EPS8 NAALAD2 MYOM1 SYNE1 CYP20A1 LYST CFB NRP2 FAT1 SERPING1 IL1R1 RASGRP2 TMEM63A

6.90e-0642916514gudmap_kidney_adult_Mesangium_Meis_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_1000

EPS8 SMARCA5 KLHL28 MYOM1 NADK2 BCAT1 THSD7B TRIP12 ZC3H6 PRPF40A NRP2 FRMD4A KCNQ5 ASPH ADAMTS15 ZNF420 GRHL3 RWDD4 EPHB1

2.39e-0582616519DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

HIVEP1 KLHL28 RAB11FIP2 OBSL1 GATM CPA2 THSD7B DENND2B GASK1B CRY1 PTPN2 MYOF PTPRF EEPD1 SERPING1 IL1R1 DCLK1 CBX8

4.00e-0578316518gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

EPS8 DPYSL3 NAALAD2 ADAMTSL3 DENND2B GASK1B CFB NRP2 MYOF FAT1 SERPING1 IL1R1 DCLK1

4.69e-0544516513GSM777043_500
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_1000

DPYSL3 NAALAD2 SMARCA5 GATM PIWIL4 CPA2 NEB MYSM1 ATL1 NDEL1 SYNJ1 IQCA1 EIF4G1 MRNIP UNC13C MGA DISP1

1.08e-0477016517gudmap_developingGonad_P2_ovary_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

EPS8 IQGAP2 CYP11A1 OBSL1 GATM DENND2B GASK1B CRY1 MYOF FAT1 EEPD1

1.35e-0436416511gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500

UNC13B EPS8 IQGAP2 CYP11A1 MAMLD1 OBSL1 GATM DENND2B GASK1B FAT1 PTPRF STARD9

1.51e-0443316512gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_500
CoexpressionAtlaskidney_adult_Mesangium_Meis_top-relative-expression-ranked_1000

CYLD EPS8 NAALAD2 HIP1 MYOM1 SYNE1 CYP20A1 IFI44 LYST CFB NRP2 ZBP1 FAT1 KCNQ5 SERPING1 IL1R1 RASGRP2 TMEM63A

1.56e-0487216518gudmap_kidney_adult_Mesangium_Meis_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

PCSK5 DPYSL3 NAALAD2 MYOM1 RAB11FIP2 OBSL1 OCRL MYSM1 CFB FNDC1 NDEL1 STARD9 EIF4G1 SERPING1 UNC13C MGA DCLK1

1.63e-0479716517gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#2_top-relative-expression-ranked_200

KLHL28 ZC3H6 NRP2 KCNQ5 EPHB1

1.75e-04671655DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k2_200
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

CASP8AP2 DPYSL3 SMARCA5 PCLO MAMLD1 GATM NEB GASK1B STK4 ALMS1 STARD9 EIF5B SERPING1 CHD6 ZNF287

1.85e-0465416515Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 BCAT1 TACC2 MYOF PTPRF BAIAP2L1 ASPH DCLK1 CACNA2D3

3.70e-0818616794e94158db52df41d71e67b02b9895a358eebee0f
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

IQGAP2 GATM NEB GASK1B NRP2 FRMD4A SERPING1 DISP1 TDRD12

3.88e-08187167959e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 DPYSL3 SYNE1 F5 NRP2 FRMD4A MYOF FAT1 NTM

4.06e-081881679b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 DPYSL3 SYNE1 F5 NRP2 FRMD4A MYOF FAT1 NTM

4.06e-081881679874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 OCRL APOC3 F5 NTM ASPH SERPING1 DCLK1 CACNA2D3

5.09e-0819316796995ee29bf403a71247de92a37dfd851be5acf2e
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 DPYSL3 MYOM1 NRP2 FNDC1 KCNQ5 CHD5 CACNA2D3

5.81e-0819616799830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 MYOM1 SYNE1 NRP2 FNDC1 STARD9 CACNA2D3 DNAH11

6.34e-08198167922e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

UNC13B EPS8 ARHGAP32 RAP1GAP OBSL1 BCAT1 NRP2 FAT1 PTPRF

6.91e-082001679e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 IQGAP2 ADAMTSL3 HPSE CEP78 ANKRD30A UNC13C DNAH11

3.80e-07178167851d2188406f04329311b2efd1108fc36617a860e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 FRMD4A FAT1 NTM TLL2 IL1R1

4.31e-0718116785f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 FRMD4A FAT1 NTM TLL2 IL1R1

4.31e-071811678c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 FRMD4A FAT1 NTM TLL2

5.09e-07185167834fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 FRMD4A FAT1 NTM TLL2

5.09e-0718516788816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 OCRL APOC3 F5 ASPH SERPING1 DCLK1 CACNA2D3

7.01e-0719316787fcfb0f76789fa8d8caa18304cb43c8fd899a81b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DPP6 DPYSL3 SYNE1 F5 NRP2 FAT1 PTPRO NTM

7.29e-0719416781374600957c7d7f0b05fd2c1186f521b9096d4ef
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 MYOF FAT1 NTM IL1R1

7.88e-07196167834e79918a448f6c19b87e1b1ce13c012b24be1f8
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 MYOF FAT1 NTM IL1R1

7.88e-0719616788f82e01ca50aa4cd6149547505b4474a02fad618
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPP6 DPYSL3 SYNE1 F5 NRP2 FAT1 PTPRO NTM

7.88e-071961678545d2e4469924d333e3f655f559c899fa1260196
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 MYOM1 SYNE1 NRP2 STARD9 CACNA2D3 DNAH11

8.18e-071971678ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARHGAP32 SYNE1 PCLO FRMD4A KCNQ5 CHD5 DCLK1 CACNA2D3

8.50e-0719816788ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 SYNE1 MAMLD1 DENND2B MYOF NTM IL1R1 DCLK1

8.50e-071981678a860246bcea847249a78fd2e86ed8e04371060db
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PCSK5 DPYSL3 OBSL1 DENND2B FNDC1 SERPING1 IL1R1 DCLK1

8.50e-071981678e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AKAP6 PRUNE2 MYOM1 SYNE1 NRP2 STARD9 CACNA2D3 DNAH11

8.50e-071981678c12e7511628db819a52959bb68580e27c00c2e41
ToppCellCOPD-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

IQGAP2 MAMLD1 BCAT1 NRP2 CD84 JARID2 EEPD1 IL1R1

8.83e-0719916781cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PRUNE2 PCSK5 SYNE1 TACC2 MYOF FNDC1 FAT1 CBX6

9.17e-072001678c5e051f1aac8dda376c342a9932785a23450e073
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 PRUNE2 PCSK5 SYNE1 ADAMTSL3 MYOF FNDC1 FAT1

9.17e-072001678f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 PCSK5 RAP1GAP SYNE1 TACC2 MYOF FNDC1 FAT1

9.17e-072001678593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 FRMD4A FAT1 NTM

2.09e-061561677dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 FRMD4A FAT1 NTM

2.09e-061561677abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 HPSE CFB ZBP1 MYOF OTOF RASGRP2

2.48e-0616016771f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP8AP2 ARHGAP32 KIAA0319L ATL1 SBNO2 BLM BAIAP2L1

3.42e-06168167727cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 EPS8 GATM CFB NRP2 FRMD4A MYOF

4.65e-061761677450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 IQGAP2 ADAMTSL3 NRP2 CEP78 ANKRD30A UNC13C

4.65e-0617616776c7edf1cb38644500bce6c5a1dd90bbe17415cdb
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 GATM CASP9 BLM ITPKC PUS10 CHD5

4.83e-0617716771d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 MAMLD1 OCRL OTOF OSBP2 CBX8 DNAH11

4.83e-0617716771dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMARCA5 MAMLD1 OCRL OTOF OSBP2 CBX8 DNAH11

4.83e-061771677426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ABCC3 DPYSL3 SYNE1 NRP2 FRMD4A NTM IL1R1

5.20e-061791677e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 BCAT1 TACC2 MYOF PTPRF BAIAP2L1 CACNA2D3

5.20e-06179167704ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 IQGAP2 ADAMTSL3 HPSE ANKRD30A UNC13C DNAH11

5.39e-061801677cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 OCRL F5 ASPH SERPING1 DCLK1 CACNA2D3

5.39e-0618016778bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP6 OCRL F5 NTM SERPING1 DCLK1 CACNA2D3

5.39e-0618016770677bf4a5177d9cbc6716195bd966eeae8de2f31
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 RAP1GAP CYP11A1 DENND2B CFB FAT1 SERPING1

5.59e-06181167735eefd874a892eaf21f24fdce89e7ea3b8ee285f
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 CYP11A1 APOC3 PTPRF PTPRO EEPD1 KLHL18

5.59e-0618116777286700396676fdc41d9723979b8b408177aceb9
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 RAP1GAP CYP11A1 DENND2B CFB FAT1 SERPING1

5.59e-061811677e4c3e0eae9f21e78b5dd18cf017bd041ffc8c968
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

CASP8AP2 CRY1 ALG9 IL1R1 STK38L MGA TMEM63A

6.23e-061841677ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EPS8 ARHGAP32 ADAMTSL3 FRMD4A MYOF FAT1 STARD9

6.23e-061841677327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

AKAP6 IQGAP2 GATM BCAT1 NRP2 CD84 FRMD4A

6.45e-0618516778207f9eff113eed429e961748c6b17d672a13b33
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP6 ABCC3 ARHGAP32 MAMLD1 GASK1B NRP2 SERPING1

6.68e-061861677f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP6 ABCC3 ARHGAP32 MAMLD1 GASK1B NRP2 SERPING1

6.68e-0618616778694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

PRUNE2 PCSK5 ABCC3 EPS8 SLC17A3 FAT1 PPP2R3A

6.92e-061871677d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SLC17A2 ALLC IQGAP2 NADK2 KIAA0319L THSD7B LYST

6.92e-061871677f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

REPS1 MYOM1 SYNE1 MAMLD1 KCNQ5 STARD9 NTM

7.17e-06188167732f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRUNE2 PCSK5 SYNE1 ADAMTSL3 MYOF FNDC1 FAT1

7.42e-0618916777ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

AKAP6 PRUNE2 HIP1 MYOF KCNQ5 UNC13C STK38L

7.42e-0618916776b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

DPYSL3 SYNE1 TACC2 GASK1B MYOF FNDC1 PPP2R3A

7.68e-061901677ff774faf3f12759d11e50ed7d189288bb79e22e1
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DPYSL3 PTPN2 NTM ADAMTS15 NUP188 IL1R1 DCLK1

7.68e-0619016770fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 DPYSL3 PCLO BCAT1 NRP2 PTPRF CBX6

8.22e-061921677b016e229300c183e14c0e2bba494bf49c7899112
ToppCell368C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

PRUNE2 DPYSL3 PCLO BCAT1 NRP2 PTPRF CBX6

8.22e-061921677ac96831492c62ad9e1f7d0b764fbdf7d8a189ad9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MAMLD1 CRY1 MYOF EEPD1 IL1R1 DCLK1

8.22e-0619216778b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTSL3 HPSE GASK1B NRP2 MYOF FNDC1 NTM

8.22e-06192167720ede290e01ad574afd122d72b59dbc52c595fad
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF FNDC1 FAT1 PTPRF BAIAP2L1 SERPING1 DCLK1

8.22e-0619216770dc1f46e40346ed0b286e53b106a812441575100
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 ADAMTSL3 DENND2B BLM OTOF TLL2 UNC13C

8.50e-061931677c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYOM1 ADAMTSL3 HPSE GASK1B NRP2 FNDC1 NTM

8.50e-06193167796c85b250d04b5f400512097d925061c6dc2906b
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 ADAMTSL3 DENND2B BLM OTOF TLL2 CACNA2D3

8.50e-061931677658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DPYSL3 NAALAD2 ADAMTSL3 FNDC1 SERPING1 DCLK1

8.80e-061941677da926441053b499cb5107ccb116fb1b3844d82b7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 IQGAP2 RAB11FIP2 TACC2 LEMD1 PTPRF UNC13C

8.80e-06194167704bfc555743f7d8821439d05ae442d15e9886c59
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DPYSL3 NAALAD2 ADAMTSL3 FNDC1 SERPING1 DCLK1

8.80e-06194167754a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DPP6 DPYSL3 F5 NRP2 FAT1 PTPRO NTM

8.80e-06194167743eb677a76634bb9a48a40e0d607c4936ae64bcc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DPYSL3 NAALAD2 ADAMTSL3 FNDC1 SERPING1 DCLK1

8.80e-061941677f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DPYSL3 ADAMTSL3 CFB FAT1 SERPING1 DCLK1

9.40e-0619616776bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DPYSL3 ADAMTSL3 CFB FAT1 SERPING1 DCLK1

9.40e-061961677c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOF FNDC1 FAT1 PTPRF ASPH SERPING1 DCLK1

9.40e-0619616772029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 SYNE1 MAMLD1 DENND2B MYOF NTM IL1R1

9.72e-06197167785a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 SYNE1 MAMLD1 DENND2B MYOF NTM IL1R1

9.72e-061971677e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

EPS8 SYNE1 MAMLD1 DENND2B MYOF NTM IL1R1

9.72e-0619716779b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP6 BCAT1 PIWIL4 TACC2 BAIAP2L1 CACNA2D3

9.74e-0613016766434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 PCLO FRMD4A KCNQ5 CHD5 DCLK1 CACNA2D3

1.00e-051981677c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 MYOF FAT1 NTM

1.04e-051991677b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellIPF-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

MAMLD1 BCAT1 GASK1B NRP2 CD84 JARID2 EEPD1

1.04e-0519916773c2b362d5e824e1a04830e70352f8818de984174
ToppCellCF-Myeloid-Monocyte_Macrophage|CF / Disease state, Lineage and Cell class

ABCC3 IQGAP2 BCAT1 GASK1B NRP2 CD84 MYOF

1.04e-051991677bf95eacb31a4a847350f9d6e95ca76c6b730c400
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DPYSL3 SYNE1 F5 NRP2 MYOF FAT1 NTM

1.04e-051991677c972d3036151403f26fa9d6271520639c281ab84
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE1 ADH5 MYOF NTM ADAMTS15 SERPING1 IL1R1

1.04e-051991677e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PCSK5 SYNE1 ADAMTSL3 ADH5 MYOF FNDC1 FAT1

1.04e-0519916776b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

AKAP6 MYOM1 SYNE1 TACC2 FRMD4A MYOF FAT1

1.07e-0520016779169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRUNE2 PCSK5 SYNE1 TACC2 MYOF FNDC1 FAT1

1.07e-05200167787827041663013f5e7273168dc8709d69840e7ce
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 PCSK5 SYNE1 TACC2 MYOF FNDC1 FAT1

1.07e-052001677c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PRUNE2 PCSK5 SYNE1 TACC2 MYOF FNDC1 FAT1

1.07e-0520016778988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRUNE2 PCSK5 SYNE1 ADAMTSL3 MYOF FNDC1 FAT1

1.07e-05200167767dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

AKAP6 MYOM1 SYNE1 ADAMTSL3 FRMD4A MYOF FAT1

1.07e-0520016778c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

PRUNE2 PCSK5 SYNE1 TACC2 ADH5 FNDC1 FAT1

1.07e-05200167702cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

AKAP6 PRUNE2 PCSK5 SYNE1 TACC2 FNDC1 FAT1

1.07e-052001677dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCellControl_saline-Endothelial-Endothelial-Vein|Control_saline / Treatment groups by lineage, cell group, cell type

DPYSL3 LYST NRP2 FRMD4A UNC13C IL1R1 DCLK1

1.07e-052001677e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

AKAP6 SYNE1 TACC2 ADAMTSL3 MYOF FNDC1 FAT1

1.07e-0520016778bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PCSK5 IFI44 THSD7B CHRNA2 NRP2 FAT1

2.37e-05152167688a810d41edb5a917c23cb5ba5a387227e1312cb
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NAALAD2 SYNE1 CD84 IQCA1 ZNF420 IL23R

2.55e-051541676e94cd11488003347120eacd3ced0a8923ed09ccc
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HIP1 MYOM1 NEB DENND2B NRP2 PTPRO

2.84e-051571676432b8719a8afd289cf48068e12c26a349d753fcc
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DPYSL3 FNDC1 FAT1 NTM GRHL3 DCLK1

2.94e-0515816763bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SYNE1 F5 FRMD4A NTM TLL2

2.94e-051581676e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 SYNE1 F5 FRMD4A NTM TLL2

2.94e-051581676d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D231|Adult / Lineage, Cell type, age group and donor

AKAP6 PRUNE2 MYOM1 THSD7B FNDC1 CHD5

3.16e-051601676d783d29150033e9181c0e30870070268fed3fd85
DrugNialamide [51-12-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A

CYLD PRUNE2 DNAJC16 SYNE1 NEB BAZ2A PTPRO NUP188 KLHL18 RASGRP2

1.95e-06196167104347_UP
DrugApigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A

HNRNPDL PTPN2 MYOF PPP2R3A ALMS1 NUP188 EIF4G3 IL1R1 CBX8

1.12e-0518916794401_DN
DrugDiethylstilbestrol [56-53-1]; Up 200; 15uM; MCF7; HT_HG-U133A

PRUNE2 ABCC3 GASK1B STK4 PTPN2 VPS13D PPP2R3A BAZ2A ASPH

1.33e-0519316793429_UP
DrugHydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A

CYLD KIAA0319L FRMD4A VPS13D MAPK14 OSBP2 NUP188 KLHL18 TMEM63A

1.38e-0519416793284_UP
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

PCLO CASP9 F5 CHRNA2 GASK1B SYNJ1 KLHL36 MRNIP RASGRP2

1.44e-0519516796183_UP
Drugcupric chloride

ALLC DPYSL3 CEL RAB11FIP2 GATM CASP9 MAD2L1BP CRY1 BLMH TARDBP PHKG1 MAPK14 IQCA1 PTPRO STK38L TALDO1

1.49e-0562316716ctd:C029892
DrugBergenin monohydrate [477-90-7]; Up 200; 11.6uM; HL60; HT_HG-U133A

AKAP6 DPYSL3 TAPT1 DNAJC16 CD84 MYOF MAPK14 PTPRF CBX8

1.50e-0519616792726_UP
DrugChlorhexidine [55-56-1]; Up 200; 8uM; MCF7; HT_HG-U133A

DPYSL3 HIP1 PCLO BCAT1 CD84 FRMD4A ASPH CBX8 RASGRP2

1.56e-0519716795403_UP
Drugnordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA

HIP1 SAMD9 KIAA0319L NEB LYST GASK1B SBNO2 VPS13D IL1R1

1.56e-0519716791003_UP
DrugAmikacin hydrate [37517-28-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A

SMARCA5 FRMD4A TARDBP MYOF FAT1 ASPH IL1R1 STK38L TMEM63A

1.56e-0519716795314_UP
Drug5707885; Down 200; 50uM; MCF7; HT_HG-U133A

ABCC3 CEL SYNE1 BCAT1 CPA2 NEB BAZ2A IL1R1 TMEM63A

1.56e-0519716796385_DN
DrugProcaine hydrochloride [51-05-8]; Up 200; 14.6uM; PC3; HT_HG-U133A

SLC17A2 ABCC3 IQGAP2 MYOF ITPKC MAPK14 OSBP2 CBX8 TMEM63A

1.76e-0520016796329_UP
DrugAC1L9IXX

EXOSC10 NTM EIF4G1 GRHL3 EIF4G3

1.93e-05451675CID000446000
DrugAC1O4QHJ

BCAT1 APOC3 CFB BLM BLMH

2.65e-05481675CID006398418
DiseaseColorectal Carcinoma

AKAP6 UNC13B ABCC3 TTLL3 SYNE1 ADAMTSL3 F5 FAT1 KCNQ5 PUS10 CHD5 PDILT CPO EIF4G1 ADAMTS15 DCLK1

2.46e-0670216616C0009402
DiseaseHerpes Zoster, response to tofacitinib

ZBP1 ACSF3 CACNA2D3

3.71e-05121663EFO_0006510, EFO_0600024
Disease4-guanidinobutanoate measurement

DNAJC16 CASP9

9.40e-0531662EFO_0800003
DiseaseTakayasu arteritis

PCSK5 HIVEP1 FRMD4A TLL2 OSBP2 CACNA2D3

1.97e-041481666EFO_1001857
Diseasekidney disease (biomarker_via_orthology)

ABCC3 GATM CASP9

2.16e-04211663DOID:557 (biomarker_via_orthology)
Diseasealcohol consumption measurement

AKAP6 DPP6 CYP11A1 PCLO ARPC1A CYP20A1 THSD7B ADH5 FRMD4A ALMS1 NTM EIF4G1 EIF5B ZNF420 MGA DCLK1 CBX8 CACNA2D3

2.33e-04124216618EFO_0007878
Diseaseinflammatory bowel disease

PCSK5 CEL F5 CFB SBNO2 STK4 PTPN2 PUS10 IL23R HSP90AA2P

2.43e-0444916610EFO_0003767
Diseaseankylosing spondylitis, psoriasis, ulcerative colitis, Crohn's disease, sclerosing cholangitis

CEL SBNO2 STK4 PTPN2 PUS10 GRHL3 IL1R1 IL23R

2.80e-042951668EFO_0000384, EFO_0000676, EFO_0000729, EFO_0003898, EFO_0004268
Diseasehippocampal atrophy

PRUNE2 F5 ZBP1 CHD6

2.82e-04561664EFO_0005039
Diseaseinterleukin-23 receptor measurement

STK4 IL23R

4.65e-0461662EFO_0801725
Diseaseurinary albumin to creatinine ratio

MYOM1 GATM THSD7B FAT1 UNC13C MGA

5.45e-041791666EFO_0007778
Diseasehereditary angioedema (is_implicated_in)

MYOF SERPING1

6.49e-0471662DOID:14735 (is_implicated_in)
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

MYOF OTOF

6.49e-0471662DOID:11724 (implicated_via_orthology)
Diseasetype 1 diabetes mellitus (is_marker_for)

CEL CASP9 APOC3 CFB

7.38e-04721664DOID:9744 (is_marker_for)
Diseaseurate measurement, bone density

AKAP6 CASP8AP2 DPYSL3 SYNE1 CFB ATL1 FNDC1 NTM DCLK1 DNAH11 EPHB1

7.99e-0461916611EFO_0003923, EFO_0004531
Disease2-aminooctanoate measurement

SLC17A3 ALMS1

8.61e-0481662EFO_0800349
DiseaseCrohn's disease

SBNO2 STK4 PTPN2 PUS10 CHD5 CHD6 IL1R1 IL23R HSP90AA2P

9.22e-044411669EFO_0000384
Diseaseasparaginase-induced acute pancreatitis

CPA2 NEB

1.10e-0391662EFO_1001507
DiseaseN-acetylkynurenine (2) measurement

SLC17A3 ALMS1

1.10e-0391662EFO_0800083
DiseasePolycystic Kidney, Autosomal Dominant

GANAB ALG9

1.10e-0391662C0085413
DiseaseAlzheimer disease, language impairment

KIAA0232 CACNA2D3

1.10e-0391662EFO_0005425, MONDO_0004975
Diseasetype 1 diabetes mellitus (is_implicated_in)

CEL APOC3 CFB IL1R1

1.37e-03851664DOID:9744 (is_implicated_in)
Diseaseinsulin sensitivity measurement, response to polyunsaturated fatty acid supplementation

EPS8 PTPRO

1.67e-03111662EFO_0004471, EFO_0009131
Diseaseankylosing spondylitis

AKAP6 PCSK5 IL1R1 IL23R

1.77e-03911664EFO_0003898
Diseaseworry measurement

HIVEP1 PPP2R3A PTPRF NTM SERPING1

1.83e-031541665EFO_0009589
Diseasealkaline phosphatase measurement

RAP1GAP SAMD9 CEL CYP20A1 DENND2B SBNO2 AZIN1 ADH5 ZBP1 BAIAP2L1 SERPING1 UNC13C EIF4G3 STK38L

1.86e-03101516614EFO_0004533
Diseaseasthma exacerbation measurement

DPP6 NTM CPO IL1R1

1.91e-03931664EFO_0007614
Diseasemean reticulocyte volume

RAP1GAP SAMD9 IQGAP2 APOC3 NEB SBNO2 AZIN1 PTPN2 PTPRF ALG9 ACSF3 OSBP2

1.96e-0379916612EFO_0010701
Diseasesocial interaction measurement

DPP6 HIVEP1 THSD7B STK4

1.99e-03941664EFO_0009592
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 LEMD1

2.00e-03121662DOID:11726 (implicated_via_orthology)
Diseaseage at menarche

HIP1 THSD7B PRPF40A ALMS1 CBX6 PDILT EIF4G1 UNC13C OSBP2 EIF4G3

2.05e-0359416610EFO_0004703
DiseaseGastric Adenocarcinoma

MAPK14 DCLK1 EPHB1

2.09e-03451663C0278701
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

SYNE1 IFI44 CWC22 IL1R1

2.58e-031011664EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseasecholestasis (biomarker_via_orthology)

ABCC3 APOC3 ADH5

2.66e-03491663DOID:13580 (biomarker_via_orthology)
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

CFB SERPING1

2.74e-03141662DOID:898 (is_marker_for)
Diseasefacial width measurement

PCLO THSD7B ANKRD30A DISP1

2.97e-031051664EFO_0007855
Diseaseulcerative colitis

CEL CFB STK4 PTPN2 PUS10 IL1R1 IL23R

2.98e-033351667EFO_0000729
Diseaseamyotrophic lateral sclerosis, age at onset

PCSK5 PTPRF

3.15e-03151662EFO_0004847, MONDO_0004976
Diseaseinterleukin 18 receptor 1 measurement

IL1R1 IL23R

3.15e-03151662EFO_0008178
Diseasequinate measurement

CFB EEPD1

3.15e-03151662EFO_0021167
Diseaseglucose metabolism measurement, age-related hearing impairment

PCSK5 SAMD9 NTM

3.16e-03521663EFO_0005782, EFO_0009367
DiseaseInfluenza

SAMD9 IFI44 SERPING1

3.16e-03521663C0021400
Diseasehair morphology measurement

FRMD4A CPO CACNA2D3

3.51e-03541663EFO_0007821
Diseasephosphatidylcholine 38:6 measurement

ABCC3 CPO

3.58e-03161662EFO_0010388
Diseaseresponse to acetylsalicylate

KLHL18 EPHB1

3.58e-03161662GO_1903492
DiseasePontoneocerebellar hypoplasia

PCLO TBC1D23

3.58e-03161662cv:C1261175
Diseasefilaggrin gene expression measurement

FRMD4A NTM

3.58e-03161662EFO_0020899
Diseaselupus nephritis (is_marker_for)

APOC3 CFB

4.05e-03171662DOID:0080162 (is_marker_for)
Diseasefibrinogen measurement, factor VII measurement

ADH5 PPP2R3A IL1R1

4.30e-03581663EFO_0004619, EFO_0004623
Diseasecreatinine measurement, glomerular filtration rate

DNAJC16 CASP9 ALMS1 PDILT

4.37e-031171664EFO_0004518, EFO_0005208
Diseasemetabolite measurement

ABCC3 CCDC121 SLC17A3 DNAJC16 GATM CASP9 MYOF ALMS1 EPHB1

4.59e-035601669EFO_0004725
Diseasealcohol use disorder (implicated_via_orthology)

UNC13B EPS8 CHRNA2 ADH5 UNC13C

5.02e-031951665DOID:1574 (implicated_via_orthology)
Diseasemean platelet volume

ARHGAP32 IQGAP2 KIAA0232 DLGAP5 CWC22 DENND2B AZIN1 ADH5 STK4 BAZ2A ALG9 SERPING1 STK38L

5.21e-03102016613EFO_0004584
Diseasenon-lobar intracerebral hemorrhage

CYP20A1 FRMD4A PTPRF

5.42e-03631663EFO_0010178
Diseaseserum homoarginine measurement

RAP1GAP GATM

5.59e-03201662EFO_0005421

Protein segments in the cluster

PeptideGeneStartEntry
KLDQEWVPYSTSASL

BCAT1

146

P54687
AIKYSTWEPEENILD

CBX6

36

O95503
DPTVKFDKQPWYIDS

CHD5

681

Q8TDI0
ELKSDDWSYLVPMTE

ALLC

126

Q8N6M5
KYKEDEPLFTSSLWG

AZIN1

341

O14977
GWKSVESVPKLVSEY

ADH5

321

P11766
IMSWSPKEKTYETDL

BAZ2A

1501

Q9UIF9
PREPKYSSNKEEWIS

ALG9

546

Q9H6U8
EPESSLTEAYEKWRE

DPYSL3

111

Q14195
EWPDSYATEKALKVS

ALMS1

1016

Q8TCU4
LPSESKQKDYEENSW

ANKRD30A

671

Q9BXX3
PSESKQKDYEESSWD

ANKRD30A

791

Q9BXX3
ALSYDTVPDTWSKLA

DNAH11

4326

Q96DT5
RSEDADSSVKEDWKY

CHRNA2

481

Q15822
WTANKIVSDYGKDPS

CPA2

191

P48052
SVFREYWNKPEETKS

ACSF3

431

Q4G176
YWNKPEETKSAFTLD

ACSF3

436

Q4G176
WTPKETGYTELVKSL

ASPH

576

Q12797
AKSEYQWITSPSVKE

CEP78

316

Q5JTW2
ESSIPRADSEKKWVY

HCCS

106

P53701
KTTFDVYTESWAQDP

CEL

381

P19835
KDWLPVSEYSSETFS

DENND2B

751

P78524
SDYKGERINSSWEKE

CASP8AP2

311

Q9UKL3
KTEEYTEQPEKVWNS

CCDC121

46

Q6ZUS5
EIVDKSVSPWSLETY

CPO

31

Q8IVL8
WNYTKFDKPHAETSE

DISP1

581

Q96F81
EEESFKNWYAKTPLG

IQCA1

786

Q86XH1
AEFYTEKDWSKKDAP

EEPD1

536

Q7L9B9
KVSDKHPEYWDTAIL

ADAMTS15

301

Q8TE58
AYIKEVDEKPASTPW

ARPC1A

171

Q92747
DPTIQDSYWKELTLD

ERAS

71

Q7Z444
WTEPYTDGSQKKQDT

ITPKC

241

Q96DU7
VEKESVKCAQYWPTD

PTPN2

116

P17706
SWDTSKKDLTEYLSR

HNRNPDL

156

O14979
KEYSKTETEAPWVVE

ABCC3

1261

O15438
WPEASTTKRKAVDTY

LEMD1

91

Q68G75
QPSESRWLKYLEKDS

MRNIP

101

Q6NTE8
TYPKIWVKVSEADSS

CFB

316

P00751
PATWYKDGQKVEESE

OBSL1

746

O75147
SAFWSEAPYLKVDTI

EPHB1

126

P54762
DSIQKPSWDFDYDTK

FAT1

4321

Q14517
DDPVSYPWISTSEKE

SLC17A3

176

O00476
CYLDAKSEQWVKETP

KLHL36

316

Q8N4N3
SAAVPDLEWYEKSEE

MAD2L1BP

11

Q15013
SSLIDIDSVPTYKWK

RASGRP2

116

Q7LDG7
WKYPDISDSISTERI

MGA

551

Q8IWI9
SAVPSAEFQWYKDDK

NTM

246

Q9P121
DSQVPKYSAKWIDGS

EURL

136

Q9NYK6
PIDWSLKYKTPDFES

GATM

146

P50440
QKTPLFETYSDWDRE

MTMR10

216

Q9NXD2
YEISVDDGPWEKQKS

NADK2

291

Q4G0N4
YEWSLSPSSKGKVVE

KIAA0319L

536

Q8IZA0
KSSDDKGIVSYLWTR

KIAA0319L

716

Q8IZA0
EWKSLTYDEVISFVP

MAPK14

336

Q16539
YSDQVWSIDELPSKQ

KIAA1109

3066

Q2LD37
YAADEKSVSIATWKP

KCNQ5

381

Q9NR82
NWRDPITKYTSDKDV

CWC22

776

Q9HCG8
PYWDNVSDSAKELIT

DCLK1

611

O15075
LEWNGIPLTSKTYEE

PCLO

4556

Q9Y6V0
SSTAESGKKPWYLEE

PCSK5

336

Q92824
YTTPSKPWDVAQDKE

KIAA0232

911

Q92628
YEEITSPWIAGEKTL

KIAA1586

641

Q9HCI6
TEELTKPGKYHFWES

FAM47B

371

Q8NA70
STDKEKSWLYTLDPI

NRP2

851

O60462
YKTLEDPWIGSESDK

DNAJC16

461

Q9Y2G8
DPTVKTDRLWHDKYT

TUBGCP3

451

Q96CW5
YTSKWTVTFAADPED

TMEM63A

391

O94886
PAADVKHTYTSWDLE

ARHGAP32

1731

A7KAX9
ISEEDKRNPTSIEYW

PPP2R3A

966

Q06190
SSEEEKEADAYTPLW

OSBP2

866

Q969R2
PKKESTFEERSYWQS

HPSE

106

Q9Y251
YISPSGEWIEELTEK

PTPRO

421

Q16827
KEEEESQPAKKTYTW

PRPF40A

376

O75400
SLKEITEKYPEWLQS

PEX19

191

P40855
GEEEKTKTYSALIWT

PUS10

406

Q3MIT2
WSESSLDEPYEKVKK

FRMD4A

611

Q9P2Q2
RIYSESAPSWLSKDD

GASK1B

206

Q6UWH4
FDPSTKIYEISNRWK

EXOSC10

711

Q01780
NYSSEWELDPVKDVL

IFI44

391

Q8TCB0
TSEDEAWKTYLENPL

GRHL3

26

Q8TE85
SLSSVETYSPETDKW

KLHL18

396

O94889
NTVQKYDPISDTWLD

KLHL28

541

Q9NXS3
EKTYEWSSEEEEPVK

ATL1

16

Q8WXF7
VLQKYSEWTSPAEDS

BLM

1281

P54132
WFPSSYTKLLEENET

BAIAP2L1

391

Q9UHR4
SQKYSTWEPEENILD

CBX8

36

Q9HC52
KPNYSSVDLSEVEWE

CACNA2D3

551

Q8IZS8
PASDSWQKLEKSREY

CHD6

441

Q8TD26
QEKTLYSFSEWPKDR

CHD6

2081

Q8TD26
SWDALPETEGKVKEY

FNDC1

381

Q4ZHG4
DPKSGSWYVETLDDI

CASP9

356

P55211
WNITKLSIEYDSEPF

CRY1

91

Q16526
YSLPSKSSKWDFEEE

GCM1

401

Q9NP62
PKTIIYWDSQTTIEK

IL23R

236

Q5VWK5
YTWTPLKTEVDESQA

DLGAP5

341

Q15398
DPTRWLSKDKNITYF

CYP11A1

436

P05108
NPPETFTWEYRDKDK

BLMH

226

Q13867
NAIYLSAKWKTTFDP

SERPING1

291

P05155
KEDAFYSWESSKDPA

EIF4G1

1556

Q04637
YSWESSKDPAEQQGK

EIF4G1

1561

Q04637
EPASFSWTYEEIKEV

LYST

3061

Q99698
PSWMEEEDLSFLYKS

MAMLD1

36

Q13495
ITYDSTPEDVKTWLQ

EPS8

721

Q12929
SEELLDKWLSYPETQ

CYP20A1

146

Q6UW02
SKNTWYIDEVAEDPA

CYLD

371

Q9NQC7
PEAKWISDTEFIYRE

DPP6

146

P42658
ESWKPTDTEGKKQYD

EIF4G3

611

O43432
ISEDAFYKWESSKDP

EIF4G3

1541

O43432
TWYKDDSKTPVSTEQ

IL1R1

56

P14778
LDKIWYESLTDPSKL

HSP90AA2P

56

Q14568
KTSVQKSSYEPLWNE

OTOF

466

Q9HC10
KESMFSWDETEYKIP

OTOF

1811

Q9HC10
SWDETEYKIPARLTL

OTOF

1816

Q9HC10
DTTYDIKVRAWTSKG

PTPRF

981

P10586
TSVLLSWEVPDSYKS

PTPRF

1026

P10586
SWEVPDSYKSAVPFK

PTPRF

1031

P10586
STYVSKPVSWADETD

EIF4B

31

P23588
IQKKYDDSDGIPWSE

JARID2

11

Q92833
SPEWDDYSDTVKDLV

PHKG1

251

Q16816
ATKHQSSEEIPKYWD

PDILT

371

Q8N807
WKPSEKLLEEEATTY

RTP1

201

P59025
QSSSYDDPWKITDEQ

REPS1

271

Q96D71
TTEPDYKSKDWVFLN

STK38L

426

Q9Y2H1
SDVLVPWEDSFLSYK

PRUNE2

931

Q8WUY3
EDPDKWKDYTSRFSE

SYNE1

1121

Q8NF91
DDYDTSEKCRTPAWT

SYNJ1

791

O43426
LPWKTTEQDLKEYFS

TARDBP

111

Q13148
SEGKTYEDDSPEWFK

F5

1681

P12259
DSEKYKPFDPSSWQR

SAMD9

501

Q5K651
LKDTNKRVESSVYWP

TDRD12

316

Q587J7
DSKESSWVTPESCLY

IQGAP2

616

Q13576
WEETFKTHSDSKPYG

GANAB

226

Q14697
LYDWKKSPDSDVAAT

EIF5B

761

O60841
LYKDSTSIPNDTDWV

GCM2

291

O75603
ASPKEFYAKNSRWTE

HIP1

856

O00291
YSIDDIDWSVKPTHT

PIWIL4

311

Q7Z3Z4
PHKRDSFIYSTWLED

RAP1GAP

601

P47736
SVEKEEKNVTYNWSP

CD84

156

Q9UIB8
EAKEPWESGYALSLT

SBNO2

1121

Q9Y2G9
QTSYEASPRILKKWE

RNF169

421

Q8NCN4
ADEPVTSTWKELYAR

STARD9

4241

Q9P2P6
SWYQKLDTKDKPSVF

OCRL

131

Q01968
SQVKTKPFDSWSYSE

AKAP6

246

Q13023
TVKDKFSEFWDLDPE

APOC3

76

P02656
SKPASEVINEYSWKV

USE1

51

Q9NZ43
TPEEWALLDTTEKYL

ZNF561

51

Q8N587
YFTKDLWPEQDIKDS

ZNF431

111

Q8TF32
PSKEEDDTVNWYSSS

ZC3H6

691

P61129
RTWVKSQYPESSEEA

ZNF287

106

Q9HBT7
DEQSKAWTIYRPEDS

ZBP1

156

Q9H171
WYNLEKRTDKSAVSG

UNC13C

1326

Q8NB66
DPKAFLIEISWTETY

RWDD4

41

Q6NW29
DDVSIYFSTPEWEKL

ZNF398

146

Q8TD17
LDTKKITPDSYALNW

TBC1D23

186

Q9NUY8
EFDTKASVYQWSPET

SLC17A2

76

O00624
YEKPEDVKSSSNRLW

TLL2

541

Q9Y6L7
QFEELYKTEAPTWET

NUP188

176

Q5SRE5
AKGTYTFDIDKWDDP

TACC2

2331

O95359
WYNLEKRTDKSAVSG

UNC13B

706

O14795
KYSTSVAEKTLEPVW

RAB11FIP2

46

Q7L804
SEWKSYPIQAVEEEA

TTLL3

161

Q9Y4R7
LSPEKNTYETELSQW

ZNF420

56

Q8TAQ5
KIPQDGDYEFLKSWT

STK4

426

Q13043
DILDALYWTATEPKE

TAPT1

216

Q6NXT6
LDPWKAAYSSLDTSK

TEX33

26

O43247
WHVANTDKKSYEPLE

TALDO1

196

P37837
EEEYTFSLKVGPWSK

THSD7B

236

Q9C0I4
TRFEDSPSYVKWGKL

SMARCA5

166

O60264
TKTHTIWYKPVREDE

TRIP12

1391

Q14669
LKYVLISKPTEWSDE

UBR2

481

Q8IWV8
PQKDQKTSAYTDWTV

HIVEP1

1956

P15822
SEPVYAAFWLSKKEN

TRIM16L

311

Q309B1
TEVKPMTSLDYAWDE

VPS13D

3541

Q5THJ4
DLITPSEATYTWTKD

ADAMTSL3

1216

P82987
KSLYESWLEKDPSPE

NAALAD2

481

Q9Y3Q0
WKPAEDTYTDANGDK

MYOF

946

Q9NZM1
WSKDYVSTEDSPRLE

MYOM1

1171

P52179
PTKPASYSVKWTIEE

MYSM1

111

Q5VVJ2
IPDFSSLKEETAYWK

NDEL1

6

Q9GZM8
EAWDRVKATSYILPS

NEB

4706

P20929