Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentspectrin-associated cytoskeleton

ANK3 SPTB SPTBN1

3.11e-069713GO:0014731
GeneOntologyCellularComponentcell cortex

ZHX3 FRY CDC42SE1 SPTB SPTBN1 MYO1F PKD2 FRYL ACTN3

4.48e-06371719GO:0005938
GeneOntologyCellularComponentautolysosome membrane

HLA-DRB1 HLA-DRB3

6.79e-054712GO:0120281
GeneOntologyCellularComponentlumenal side of endoplasmic reticulum membrane

HLA-DRB1 HLA-DRB3 PKD2

2.27e-0435713GO:0098553
GeneOntologyCellularComponentcortical actin cytoskeleton

SPTB SPTBN1 MYO1F ACTN3

2.84e-0493714GO:0030864
GeneOntologyCellularComponentspectrin

SPTB SPTBN1

4.03e-049712GO:0008091
GeneOntologyCellularComponentlumenal side of membrane

HLA-DRB1 HLA-DRB3 PKD2

5.82e-0448713GO:0098576
GeneOntologyCellularComponentCOPI vesicle coat

COPA SCYL1

8.66e-0413712GO:0030126
GeneOntologyCellularComponentcortical cytoskeleton

SPTB SPTBN1 MYO1F ACTN3

9.77e-04129714GO:0030863
GeneOntologyCellularComponentspindle

FRY CEP250 PKD2 IRAG2 DIDO1 ESPL1 DSN1

1.08e-03471717GO:0005819
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ABCA3 MALRD1 COPA SLC17A9 INPP4A HLA-DRB1 HLA-DRB3 PKD2 IRAG2 SCYL1 RND2 NOS3

1.40e-0313077112GO:0030659
GeneOntologyCellularComponentMHC class II protein complex

HLA-DRB1 HLA-DRB3

1.50e-0317712GO:0042613
GeneOntologyCellularComponentvesicle membrane

ABCA3 MALRD1 COPA SLC17A9 INPP4A HLA-DRB1 HLA-DRB3 PKD2 IRAG2 SCYL1 RND2 NOS3

1.57e-0313257112GO:0012506
GeneOntologyCellularComponentautolysosome

HLA-DRB1 HLA-DRB3

1.68e-0318712GO:0044754
GeneOntologyCellularComponentCOPI-coated vesicle membrane

COPA SCYL1

1.87e-0319712GO:0030663
GeneOntologyCellularComponentcostamere

ANK3 SVIL

2.51e-0322712GO:0043034
DomainCell_morpho_N

FRY FRYL

1.47e-052722IPR025614
DomainMOR2-PAG1_mid

FRY FRYL

1.47e-052722IPR029473
DomainMOR2-PAG1_mid

FRY FRYL

1.47e-052722PF14228
DomainMOR2-PAG1_C

FRY FRYL

1.47e-052722PF14225
DomainMOR2-PAG1_N

FRY FRYL

1.47e-052722PF14222
DomainCell_Morphogen_C

FRY FRYL

1.47e-052722IPR025481
DomainDUF3498

DAB2IP RASAL2

4.39e-053722IPR021887
DomainDUF3498

DAB2IP RASAL2

4.39e-053722PF12004
DomainSpectrin_bsu

SPTB SPTBN1

8.75e-054722IPR016343
DomainActinin_actin-bd_CS

SPTB SPTBN1 ACTN3

9.20e-0523723IPR001589
DomainSpectrin

SPTB SPTBN1 ACTN3

9.20e-0523723PF00435
DomainACTININ_2

SPTB SPTBN1 ACTN3

9.20e-0523723PS00020
DomainACTININ_1

SPTB SPTBN1 ACTN3

9.20e-0523723PS00019
DomainSpectrin_repeat

SPTB SPTBN1 ACTN3

1.87e-0429723IPR002017
DomainSpectrin/alpha-actinin

SPTB SPTBN1 ACTN3

2.51e-0432723IPR018159
DomainSPEC

SPTB SPTBN1 ACTN3

2.51e-0432723SM00150
DomainMHC_II_b_N

HLA-DRB1 HLA-DRB3

4.04e-048722PD000328
DomainMHC_II_beta

HLA-DRB1 HLA-DRB3

5.18e-049722PF00969
DomainMHC_II_b_N

HLA-DRB1 HLA-DRB3

5.18e-049722IPR000353
DomainMHC_II_beta

HLA-DRB1 HLA-DRB3

5.18e-049722SM00921
DomainRasGAP

DAB2IP RASAL2

1.29e-0314722SM00323
DomainMHC_II_a/b_N

HLA-DRB1 HLA-DRB3

1.29e-0314722IPR014745
Domain-

HLA-DRB1 HLA-DRB3

1.29e-03147223.10.320.10
DomainRasGAP_CS

DAB2IP RASAL2

1.29e-0314722IPR023152
DomainRasGAP

DAB2IP RASAL2

1.49e-0315722PF00616
DomainRAS_GTPASE_ACTIV_1

DAB2IP RASAL2

1.49e-0315722PS00509
DomainRAS_GTPASE_ACTIV_2

DAB2IP RASAL2

1.49e-0315722PS50018
Domain-

DAB2IP RASAL2

1.70e-03167221.10.506.10
DomainC2

DAB2IP PIK3C2B INPP4A RASAL2

1.94e-03137724SM00239
DomainCH

SPTB SPTBN1 ACTN3

2.02e-0365723SM00033
DomainRasGAP_dom

DAB2IP RASAL2

2.15e-0318722IPR001936
DomainC2

DAB2IP PIK3C2B INPP4A RASAL2

2.21e-03142724PS50004
DomainCH

SPTB SPTBN1 ACTN3

2.50e-0370723PF00307
Domain-

DAB2IP PIK3C2B INPP4A RASAL2

2.57e-031487242.60.40.150
Domain-

SPTB SPTBN1 ACTN3

2.60e-03717231.10.418.10
DomainTPR-contain_dom

TRANK1 SMG7 TONSL EMC2

2.69e-03150724IPR013026
DomainCH

SPTB SPTBN1 ACTN3

2.82e-0373723PS50021
DomainCH-domain

SPTB SPTBN1 ACTN3

3.04e-0375723IPR001715
DomainC2_dom

DAB2IP PIK3C2B INPP4A RASAL2

3.71e-03164724IPR000008
DomainTPR_REGION

TRANK1 SMG7 TONSL EMC2

3.79e-03165724PS50293
DomainTPR

TRANK1 SMG7 TONSL EMC2

3.79e-03165724PS50005
DomainRho_GTPase_activation_prot

DAB2IP STARD8 RASAL2

4.77e-0388723IPR008936
Pubmed

Cell organization, growth, and neural and cardiac development require αII-spectrin.

ANK3 SPTB SPTBN1

1.10e-061074322159418
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

DAB2IP STARD8 ANK3 BRAF SLC17A9 SPTBN1 PEG3 OGDHL DIDO1 FRYL GCNT2 ESPL1

2.93e-061084741211544199
Pubmed

Paediatric celiac patients carrying the HLA-DR7-DQ2 and HLA-DR3-DQ2 haplotypes display small clinical differences.

HLA-DRB1 HLA-DRB3

4.47e-06274224628273
Pubmed

Mutations and selection in the generation of class II histocompatibility antigen polymorphism.

HLA-DRB1 HLA-DRB3

4.47e-0627426589154
Pubmed

Cyst formation in kidney via B-Raf signaling in the PKD2 transgenic mice.

BRAF PKD2

4.47e-06274219098310
Pubmed

Clinical variability and probable founder effect in oculocutaneous albinism type 7.

MALRD1 IRAG2

4.47e-06274231694064
Pubmed

DRB1*03 diversity and DRB3 associations in five major population groups in the United States.

HLA-DRB1 HLA-DRB3

4.47e-06274211872240
Pubmed

A cellular and functional split in the DRw8 haplotype is due to a single amino acid replacement (DR beta ser 57- asp 57).

HLA-DRB1 HLA-DRB3

4.47e-0627422497068
Pubmed

Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers.

DAB2IP RASAL2

4.47e-06274227974415
Pubmed

The conundrum of HLA-DRB1*14:01/*14:54 and HLA-DRB3*02:01/*02:02 mismatches in unrelated hematopoietic SCT.

HLA-DRB1 HLA-DRB3

4.47e-06274220972469
Pubmed

Development of a new HLA-DRB real-time PCR typing method.

HLA-DRB1 HLA-DRB3

4.47e-06274215620466
Pubmed

Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles.

HLA-DRB1 HLA-DRB3

4.47e-06274216320316
Pubmed

Description of two new HLA-DRB alleles (DRB1*0310 and DRB3*01012) found in a Spanish infant.

HLA-DRB1 HLA-DRB3

4.47e-0627429234492
Pubmed

Tracking antigen-specific T-cells during clinical tolerance induction in humans.

HLA-DRB1 HLA-DRB3

4.47e-06274220543955
Pubmed

Association of HLA-DR3 with anti-cyclic citrullinated peptide antibody-negative rheumatoid arthritis.

HLA-DRB1 HLA-DRB3

4.47e-06274216200610
Pubmed

HLA-DRB1*15:01 and HLA-DRB3*02:02 in PLA2R-Related Membranous Nephropathy.

HLA-DRB1 HLA-DRB3

4.47e-06274228028136
Pubmed

HLA-DRB1 and -DRB3 allele frequencies and haplotypic associations in Koreans.

HLA-DRB1 HLA-DRB3

4.47e-06274215041167
Pubmed

The unusual DRB1*08:01 haplotype carrying DRB3*02:02 confirmed in a Dutch family.

HLA-DRB1 HLA-DRB3

4.47e-06274223742216
Pubmed

Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.

HLA-DRB1 HLA-DRB3

4.47e-06274230282837
Pubmed

Ankyrin-G and beta2-spectrin collaborate in biogenesis of lateral membrane of human bronchial epithelial cells.

ANK3 SPTBN1

4.47e-06274217074766
Pubmed

[An evaluation of HLA class 2 alleles and anti-islet antibodies as evidence for non-autoimmune diabetes in Wolfram syndrome].

HLA-DRB1 HLA-DRB3

4.47e-06274221447263
Pubmed

HLA-DRB1 reduces the risk of type 2 diabetes mellitus by increased insulin secretion.

HLA-DRB1 HLA-DRB3

4.47e-06274221484216
Pubmed

ERK5 is activated by oncogenic BRAF and promotes melanoma growth.

BRAF MAPK7

4.47e-06274229483645
Pubmed

The mouse zinc-fingers and homeoboxes (ZHX) family; ZHX2 forms a heterodimer with ZHX3.

ZHX3 ZHX2

4.47e-06274214659886
Pubmed

Sporadic inclusion body myositis: phenotypic variability and influence of HLA-DR3 in a cohort of 57 Australian cases.

HLA-DRB1 HLA-DRB3

4.47e-06274218258695
Pubmed

Molecular, serological and genetic studies on two new HLA-DRB1 alleles--HLA-DRB1*0704 and HLA-DRB1*1507.

HLA-DRB1 HLA-DRB3

4.47e-06274211144299
Pubmed

Two novel DRB alleles detected by PCR-SSO and confirmed by sequencing: DRB1*0317 and DRB3*0210.

HLA-DRB1 HLA-DRB3

4.47e-06274211169247
Pubmed

HLA-DRB1*03, DRB1*11 or DRB1*12 and their respective DRB3 specificities in clinical variants of sarcoidosis.

HLA-DRB1 HLA-DRB3

4.47e-06274211169267
Pubmed

DRB1*14 diversity and DRB3 associations in four major population groups in the United States.

HLA-DRB1 HLA-DRB3

4.47e-06274212144619
Pubmed

Three new DRB alleles routinely identified by sequence-based typing: DRB1*010103, DRB1*0326 and DRB3*0219.

HLA-DRB1 HLA-DRB3

4.47e-06274215496209
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ZHX3 CACTIN BRAF COPA KDM5C SPTBN1 SVIL DIDO1 ESPL1 STRIP1

5.59e-06774741015302935
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

DAB2IP SMG7 COPA PIK3C2B SLC7A6OS SSX2IP SCYL1 GRB10 MAPK7 ESPL1 SOX13

1.19e-051038741126673895
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTB SPTBN1

1.34e-05374211294830
Pubmed

A novel DRB3 allele (DRB3*0208), a new allelic variant of DRB1*1502 (DRB1*15023) and two new DQB1 (DQB1*03012 and DQB1*0614) alleles.

HLA-DRB1 HLA-DRB3

1.34e-0537429802612
Pubmed

Ankyrin-G is a molecular partner of E-cadherin in epithelial cells and early embryos.

ANK3 SPTBN1

1.34e-05374217620337
Pubmed

HLA-DR genotypes influence age at disease onset in children and juveniles with type 1 diabetes mellitus.

HLA-DRB1 HLA-DRB3

1.34e-05374220371654
Pubmed

Association of HLA-DR3 and HLA-DR4 with sinonasal polyposis in Mexican Mestizos.

HLA-DRB1 HLA-DRB3

1.34e-05374216815190
Pubmed

Influence of MHC class II genotype on outcome of infection with hepatitis C virus. The HENCORE group. Hepatitis C European Network for Cooperative Research.

HLA-DRB1 HLA-DRB3

1.34e-05374210609818
Pubmed

Impact of HLA class I high-resolution mismatches on chronic graft-versus-host disease and survival of patients given hematopoietic stem cell grafts from unrelated donors.

HLA-DRB1 HLA-DRB3

1.34e-05374215531903
Pubmed

Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma.

ZHX3 ZHX2

1.34e-05374228152006
Pubmed

HLA-DR beta-chain polymorphism. Second domain polymorphism reflects evolutionary relatedness of alleles and may explain public serologic epitopes.

HLA-DRB1 HLA-DRB3

1.34e-0537422471740
Pubmed

Molecular analysis of the HLA class II genes in two DRw6-related haplotypes, DRw13 DQw1 and DRw14 DQw3.

HLA-DRB1 HLA-DRB3

1.34e-0537422493052
Pubmed

Human leukocyte antigen class II associations with hepatitis C virus clearance and virus-specific CD4 T cell response among Caucasians and African Americans.

HLA-DRB1 HLA-DRB3

1.34e-05374218537178
Pubmed

Re-evaluation of DRB1*0702: evidence for only one allele, DRB1*0701, encoding the beta chain of the HLA-DR7 antigen.

HLA-DRB1 HLA-DRB3

1.34e-0537428016840
Pubmed

Binding domain regulation of MHC class II molecule assembly, trafficking, fate, and function.

HLA-DRB1 HLA-DRB3

1.34e-0537428775462
Pubmed

β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.

SPTB SPTBN1

1.34e-05374232425157
Pubmed

Frequency and impact of obstetric complications prior and subsequent to unexplained secondary recurrent miscarriage.

HLA-DRB1 HLA-DRB3

1.34e-05374220395221
Pubmed

Long-term follow-up of hepatitis C virus infection: HLA class II loci influences the natural history of the disease.

HLA-DRB1 HLA-DRB3

1.34e-05374212694584
Pubmed

Polymorphism in the regulatory region of HLA-DRB genes correlating with haplotype evolution.

HLA-DRB1 HLA-DRB3

1.34e-0537428462990
Pubmed

Polymorphism of HLA-DR beta chains in DR4, -7, and -9 haplotypes: implications for the mechanisms of allelic variation.

HLA-DRB1 HLA-DRB3

1.34e-0537423466180
Pubmed

Crystallographic structure of the human leukocyte antigen DRA, DRB3*0101: models of a directional alloimmune response and autoimmunity.

HLA-DRB1 HLA-DRB3

1.34e-05374217583734
Pubmed

HLA class II influences humoral autoimmunity in patients with type 2 autoimmune hepatitis.

HLA-DRB1 HLA-DRB3

1.34e-05374217050030
Pubmed

Influence of nitric oxide synthase gene polymorphisms on the risk of cardiovascular events in rheumatoid arthritis.

HLA-DRB1 NOS3

1.34e-05374219327239
Pubmed

Masking of a cathepsin G cleavage site in vivo contributes to the proteolytic resistance of major histocompatibility complex class II molecules.

HLA-DRB1 HLA-DRB3

1.34e-05374220331476
Pubmed

Tumor cells with KRAS or BRAF mutations or ERK5/MAPK7 amplification are not addicted to ERK5 activity for cell proliferation.

BRAF MAPK7

1.34e-05374226959608
Pubmed

The complete amino acid sequence for brain beta spectrin (beta fodrin): relationship to globin sequences.

SPTB SPTBN1

1.34e-0537428479293
Pubmed

The association of HLA-DQB1, -DQA1 and -DPB1 alleles with anti- glomerular basement membrane (GBM) disease in Chinese patients.

HLA-DRB1 HLA-DRB3

1.34e-05374221569485
Pubmed

A male-specific increase in the HLA-DRB4 (DR53) frequency in high-risk and relapsed childhood ALL.

HLA-DRB1 HLA-DRB3

1.34e-05374212008082
Pubmed

Developmental expression of brain beta-spectrin isoform messenger RNAs.

SPTB SPTBN1

1.34e-0537421467942
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

DAB2IP ANK3 SPTBN1 NLGN2 RASAL2 CNTN1

1.64e-0525174627507650
Pubmed

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.

TMEM132D SVIL CCDC85A CNTN1

1.74e-057274433726789
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

BRAF CEP250 SPTBN1 SVIL FRYL RASAL2

1.79e-0525574615324660
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DAB2IP RSBN1 ZHX3 PEG3 GRB10 ZHX2 STRIP1

2.62e-0540774712693553
Pubmed

Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study.

HLA-DRB1 HLA-DRB3

2.67e-05474216879749
Pubmed

Allelic variation in the DR subregion of the human major histocompatibility complex.

HLA-DRB1 HLA-DRB3

2.67e-0547423476943
Pubmed

PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5.

MAPK7 NOS3

2.67e-05474220538799
Pubmed

Genetic susceptibility to breast cancer: HLA DQB*03032 and HLA DRB1*11 may represent protective alleles.

HLA-DRB1 HLA-DRB3

2.67e-05474211027344
Pubmed

HLA class II alleles in systemic sclerosis patients with anti-RNA polymerase I/III antibody: associations with subunit reactivities.

HLA-DRB1 HLA-DRB3

2.67e-05474214677183
Pubmed

Human leukocyte antigen association in idiopathic thrombotic thrombocytopenic purpura: evidence for an immunogenetic link.

HLA-DRB1 HLA-DRB3

2.67e-05474219922436
Pubmed

Additional sequence analysis outside exon 2 clarifies DRB1*12 and DRB1*14 allelic frequencies in Koreans.

HLA-DRB1 HLA-DRB3

2.67e-05474219286445
Pubmed

Analyzing the Mycobacterium tuberculosis immune response by T-cell receptor clustering with GLIPH2 and genome-wide antigen screening.

HLA-DRB1 HLA-DRB3

2.67e-05474232341563
Pubmed

Next-Generation Sequencing Reveals That HLA-DRB3, -DRB4, and -DRB5 May Be Associated With Islet Autoantibodies and Risk for Childhood Type 1 Diabetes.

HLA-DRB1 HLA-DRB3

2.67e-05474226740600
Pubmed

Association of HLA-DR and -DQ genes with narcolepsy in Koreans: comparison with two control groups, randomly selected subjects and DRB1*1501-DQB1*0602--positive subjects.

HLA-DRB1 HLA-DRB3

2.67e-05474217002906
Pubmed

The spectrin-based membrane skeleton stabilizes mouse megakaryocyte membrane systems and is essential for proplatelet and platelet formation.

SPTB SPTBN1

2.67e-05474221566095
Pubmed

Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin.

SPTB SPTBN1

2.67e-0547423862089
Pubmed

Apparent structural differences at the tetramerization region of erythroid and nonerythroid beta spectrin as discriminated by phage displayed scFvs.

SPTB SPTBN1

2.67e-05474221412925
Pubmed

HLA-DRB alleles and systemic lupus erythematosus in Jamaicans.

HLA-DRB1 HLA-DRB3

2.67e-05474212144077
Pubmed

Associations of human leukocyte antigen DRB with resistance or susceptibility to HIV-1 infection in the Pumwani Sex Worker Cohort.

HLA-DRB1 HLA-DRB3

2.67e-05474218520346
Pubmed

Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin.

ANK3 CNTN1

2.67e-05474214761957
Pubmed

HLA DR B1*04, *07-restricted epitopes on Keratin 17 for autoreactive T cells in psoriasis.

HLA-DRB1 HLA-DRB3

2.67e-05474215795121
Pubmed

Analysis of HLA haplotypes in autoimmune hepatitis type 1: identifying the major susceptibility locus.

HLA-DRB1 HLA-DRB3

2.67e-05474211182227
Pubmed

HLA molecules and nasal carriage of Staphylococcus aureus isolated from dialysis and kidney transplant patients at a hospital in Southern Brazil.

HLA-DRB1 HLA-DRB3

2.67e-05474222321387
Pubmed

Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site.

SPTB SPTBN1

2.67e-05474212820899
Pubmed

Molecular analysis of human class II transplantation antigens and their genes.

HLA-DRB1 HLA-DRB3

2.67e-0547426415003
Pubmed

Two major histocompatibility complex haplotypes influence susceptibility to sporadic inclusion body myositis: critical evaluation of an association with HLA-DR3.

HLA-DRB1 HLA-DRB3

2.67e-05474215496200
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DAB2IP FRY ANK3 SPTBN1 SVIL DIDO1 NLGN2 RASAL2 CNTN1 STRIP1

3.65e-05963741028671696
Pubmed

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.

HLA-DRB1 HLA-DRB3

4.45e-0557427477400
Pubmed

HLA class II amino acid epitopes as susceptibility markers of sarcoidosis.

HLA-DRB1 HLA-DRB3

4.45e-05574217559577
Pubmed

Antinuclear antibodies and HLA class II alleles in Jamaican patients with systemic lupus erythematosus.

HLA-DRB1 HLA-DRB3

4.45e-05574217910142
Pubmed

Major histocompatibility complex class II molecules promote human immunodeficiency virus type 1 assembly and budding to late endosomal/multivesicular body compartments.

HLA-DRB1 HLA-DRB3

4.45e-05574216973583
Pubmed

ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome.

ZHX3 ZHX2

4.45e-05574217056598
Pubmed

Genetic variability in HIV-1 gp120 affects interactions with HLA molecules and T cell receptor.

HLA-DRB1 HLA-DRB3

4.45e-0557421970352
Pubmed

Cross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1.

HLA-DRB1 HLA-DRB3

4.45e-0557427645219
Pubmed

A comparison of HLA-DR and -DQ allele and haplotype frequencies in Trinidadian populations of African, South Asian, and mixed ancestry.

HLA-DRB1 HLA-DRB3

4.45e-05574212392858
Pubmed

Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis.

HLA-DRB1 HLA-DRB3

4.45e-05574215908298
Pubmed

HLA-DQ8 and the HLA-DQ8-DR4 haplotype are positively associated with the hevein-specific IgE immune response in health care workers with latex allergy.

HLA-DRB1 HLA-DRB3

4.45e-05574212209103
Pubmed

The role of HLA molecules in susceptibility to chronic rheumatic heart disease.

HLA-DRB1 HLA-DRB3

4.45e-05574216426242
Pubmed

HLA-DQA is associated with abdominal aortic aneurysms in the Belgian population.

HLA-DRB1 HLA-DRB3

4.45e-05574217182961
Pubmed

HLA-DRB4 as a genetic risk factor for Churg-Strauss syndrome.

HLA-DRB1 HLA-DRB3

4.45e-05574217763415
Pubmed

NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells.

HLA-DRB1 HLA-DRB3

4.45e-05574211782380
GeneFamilyEF-hand domain containing|Spectrins

SPTB SPTBN1

1.82e-0475421113
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

DAB2IP RASAL2

3.88e-0410542830
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZHX3 ZHX2

8.97e-0415542529
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTB SPTBN1 GRB10 RASAL2

3.32e-03206544682
CoexpressionKOYAMA_SEMA3B_TARGETS_DN

RSBN1 BRAF CDC42SE1 SVIL PEG3 DNAJC21 RASAL2 ATL1

8.69e-06364748M2029
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 SPTBN1 ZNF521 GRB10 NOS3 RASAL2

3.66e-08198737fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 CCDC85A RASAL2

4.98e-071797368f9e538c822940785130297712b75131812a4603
ToppCellfacs-Heart-RV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP FRY PIK3C2B NOS3 CCDC85A RASAL2

7.27e-0719173684ebb9f8e975acc88aa600c08a8aa791256948a6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 NOS3 RASAL2

7.96e-07194736f76808666fb875fc787751cbfd924d9be20a8192
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 ZNF521 NOS3 CCDC85A RASAL2

7.96e-07194736b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 NOS3 RASAL2

7.96e-07194736f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 NOS3 RASAL2

7.96e-07194736a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 SPTBN1 ZNF521 NOS3 CCDC85A

8.45e-071967368ad8efb631164b46f0c082572270188e5ead20bf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 CCDC85A RASAL2

8.45e-0719673622767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 SPTBN1 ZNF521 NOS3 CCDC85A

8.45e-071967369606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 CCDC85A RASAL2

8.45e-07196736adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 ZNF521 GRB10 NOS3 CCDC85A RASAL2

8.71e-071977360f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 NOS3 RASAL2

8.97e-0719873607701c73137947ed4a27e225975329235bbb8734
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DRB1 SPTBN1 ZNF521 GRB10 NOS3 RASAL2

8.97e-0719873631ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PIK3C2B SPTBN1 ZNF521 GRB10 NOS3 CCDC85A

8.97e-071987368689090bce9ab6e8f122426a404037e572c6713b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DRB1 SPTBN1 ZNF521 GRB10 NOS3 RASAL2

8.97e-071987360a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIK3C2B SPTB ZNF521 NOS3 CCDC85A

4.82e-061507354f31867cb85253ff6d22f3b02ef972a42cb41123
ToppCell10x5'-Liver-Lymphocytic_T_CD4-Tfh|Liver / Manually curated celltypes from each tissue

ABCA3 ANK3 GRB10 ANKRD18A ATL1

5.84e-0615673585bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

STARD8 PIK3C2B SPTBN1 GRB10 CCDC85A

8.61e-06169735987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PIK3C2B FRYL SOX13 NOS3 CCDC85A

1.14e-051797352a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACTIN TONSL GCNT2 DNAH8 SOX13

1.20e-05181735709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACTIN WDR87 HLA-DRB1 GCNT2 DNAH8

1.33e-051857353563dd39ec58d3273f95f5bb36b9ccdc0aafb63a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 ZNF521 GRB10 NOS3 RASAL2

1.40e-0518773535c382c0aabd46906113e5db30ea24bb8e658899
ToppCellCOVID-19-Heart-EC_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SPTBN1 GRB10 NOS3 CCDC85A RASAL2

1.48e-05189735fe49852ba15f948b384d6b4c258927c70b741357
ToppCelldroplet-Limb_Muscle-nan-3m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5C CEP250 NLRC5 RND2 GCNT2

1.48e-0518973516a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCellfacs-Heart-RV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP FRY PIK3C2B NOS3 CCDC85A

1.52e-0519073589d1d686cc683206534e2157554d7d0df5d53497
ToppCellfacs-Heart-RV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP FRY PIK3C2B NOS3 CCDC85A

1.52e-0519073565ba6c4f4a2905c0bf4ff99518ae49e3dfd5e640
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3C2B SPTBN1 ZNF521 CCDC85A RASAL2

1.52e-05190735474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 CCDC85A RASAL2

1.56e-05191735f663131a4810584c5854bd64ee7991a237b7707f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 ZNF521 NOS3 RASAL2

1.59e-051927351ee4783051ec94ea94600f040edcb385fc4289f1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 ZNF521 NOS3 CCDC85A

1.59e-0519273528eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP STARD8 PIK3C2B SPTBN1 RASAL2

1.63e-05193735826b8dd801298b3e0cd76232feae5a14026b8806
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP STARD8 PIK3C2B SPTBN1 RASAL2

1.63e-0519373587d3a577d37fb0cb4b6313c596310de452bc3872
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP STARD8 PIK3C2B SPTBN1 RASAL2

1.63e-05193735d485634c564b268e344b6a2863c26f6adaec9e38
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZHX3 TRANK1 ANK3 PEG3 ACTN3

1.63e-051937351aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 GRB10 RASAL2

1.68e-0519473574a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PIK3C2B ZNF521 GRB10 CCDC85A RASAL2

1.68e-051947350b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 ZNF521 CCDC85A RASAL2

1.68e-05194735fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 PEG3 GRB10 ACTN3 ZHX2

1.76e-051967353dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B ZNF521 GRB10 NOS3 RASAL2

1.76e-05196735ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DRB1 SPTBN1 ZNF521 NOS3 RASAL2

1.76e-051967358f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DRB1 SPTBN1 ZNF521 NOS3 RASAL2

1.76e-0519673548b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 NOS3 CCDC85A

1.76e-05196735b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DRB1 SPTBN1 ZNF521 NOS3 RASAL2

1.76e-05196735473980c827443464d08a0be28c53e3536369b12a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 NOS3 CCDC85A

1.76e-05196735145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD8 HLA-DRB1 ZNF521 GRB10 NOS3

1.76e-05196735e224338490691d92c1f70b57112fabdcc92b06a9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B SPTBN1 ZNF521 NOS3 CCDC85A

1.76e-05196735d0ff1082898d2db47c88d2678466514e9e9193d3
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD8 HLA-DRB1 ZNF521 GRB10 NOS3

1.80e-05197735c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 ZNF521 GRB10 NOS3 RASAL2

1.80e-05197735cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ABCA3 ANK3 IRAG2 OGDHL GCNT2

1.80e-051977353d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

HLA-DRB1 GRB10 NOS3 CCDC85A RASAL2

1.80e-05197735ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STARD8 HLA-DRB1 ZNF521 GRB10 NOS3

1.80e-051977352844dbcd0a673ed81c99920aa45858651a00736d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 ZNF521 GRB10 NOS3 RASAL2

1.80e-05197735412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 GRB10 NOS3 CCDC85A RASAL2

1.85e-05198735451003a21162eeae90739fdb502bb50b362d80c8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 ZNF521 NOS3 CCDC85A

1.85e-05198735953630dbe3154b1b102b87de0feca2cbf124eabe
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SPTBN1 GRB10 NOS3 CCDC85A RASAL2

1.85e-05198735440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2B HLA-DRB1 ZNF521 NOS3 CCDC85A

1.85e-051987358e45551224fbb30c0658ad47dd98335ecf165437
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRY ANK3 PEG3 RASAL2 CNTN1

1.85e-051987350ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellCOVID-19_Mild-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

KLHL11 ANK3 PIK3C2B DNAJC30

8.27e-05140734b1429028c52f84127b894b93b55961badcd5246f
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132D KIAA2012 CNTN1 STRIP1

8.98e-051437344a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMEM132D KIAA2012 CNTN1 STRIP1

8.98e-0514373465328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC1|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WDR87 HLA-DRB1 MYO1F IRAG2

1.08e-041507343dc23a37dbeb7f9df93683702a7838f7cc3ec9cc
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MALRD1 TTLL11 SVIL KIAA2012

1.20e-041547346c1e7682c43c40b58b371c58deb10b839700ebcc
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANK3 WDR87 ALDH7A1 CNTN1

1.29e-041577346ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA3 MALRD1 ANK3 TMEM132D

1.35e-04159734e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA3 ANK3 SLC17A9 GCNT2

1.45e-041627348e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA3 ANK3 SLC17A9 GCNT2

1.45e-04162734e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRANK1 IRAG2 ESPL1 KIAA2012

1.60e-041667340a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_MEMP|bone_marrow / Manually curated celltypes from each tissue

ZNF521 GRB10 OGDHL CNTN1

1.60e-041667349788486582cc2c5f28b9ea015e235732f9fefb1e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANK3 BRAF KDM5C SPTBN1

1.63e-04167734ced6ed9b412739c6ced622523347c10295edbf53
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PIGL GRB10 MAPK7 ATL1

1.67e-0416873453a982869dbf14f6a948589be9f2f3df3b9a7e97
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

ABCA3 SPTB EMC2 ZHX2

1.67e-04168734c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTB IRAG2 OGDHL CNTN1

1.75e-0417073417bd7fd25a2657cb536ad47e294332920f759e95
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

ANK3 SPTBN1 CCDC85A RASAL2

1.75e-04170734e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

DAB2IP FRY PIK3C2B NOS3

1.87e-04173734ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL11 PIK3C2B SCYL1 DNAH8

1.87e-041737348bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL11 PIK3C2B SCYL1 DNAH8

1.87e-041737343e3c61468e703330788a10d850ef41a85680f86d
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

DAB2IP FRY PIK3C2B NOS3

1.87e-0417373422200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DRB1 IRAG2 NLRC5 ZHX2

1.87e-0417373467c342295b8a06ce38e081ba74478c568917a396
ToppCell368C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SPTB ZNF521 KIAA2012 SOX13

1.87e-041737348cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell368C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SPTB ZNF521 KIAA2012 SOX13

1.87e-04173734fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DAB2IP FRY SPTB GRB10

1.91e-04174734015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

TMEM132D SPTBN1 GCNT2 CCDC85A

1.91e-04174734548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellfacs-Heart-RV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP SPTBN1 NOS3 CCDC85A

2.00e-04176734fb3d03f64592e1df1d9785d9f2e70938d7ff9ce8
ToppCellfacs-Heart-RV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP SPTBN1 NOS3 CCDC85A

2.00e-041767343270a36fc91a5583646ffeb70bfcbc5af7292aac
ToppCellfacs-Heart-RV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP SPTBN1 NOS3 CCDC85A

2.00e-0417673499410c121f55adbc7fcc013c8fa8905a45dba76b
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP SPTBN1 NOS3 CCDC85A

2.04e-04177734ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP SPTBN1 NOS3 CCDC85A

2.04e-04177734f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP SPTBN1 NOS3 CCDC85A

2.04e-04177734cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK3 SVIL PEG3 CNTN1

2.04e-041777347af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DRB1 MYO1F IRAG2 NLRC5

2.04e-04177734ecd26d086c1aff3be442fcb055611a563ca034ef
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZHX3 DNAH8 RASAL2 ATL1

2.13e-04179734025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP PIK3C2B SPTBN1 RASAL2

2.17e-04180734dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DAB2IP PIK3C2B SPTBN1 RASAL2

2.17e-04180734423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL11 SPTB PEG3 CCDC85A

2.17e-0418073479c5725f02e038d0187f4a1e1591f2492538aa57
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3C2B DIDO1 FRYL NOS3

2.22e-041817344ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

ABCA3 ANK3 SPTBN1 CCDC85A

2.32e-04183734dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 GRB10 NOS3 RASAL2

2.32e-04183734dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 GRB10 NOS3 RASAL2

2.32e-041837344759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CACTIN SLC17A9 DSN1 ALDH7A1

2.32e-04183734dd15e1463a0d57d14800de0df0645c81c56926ae
DrugTerazosin hydrochloride [63590-64-7]; Up 200; 9.4uM; MCF7; HT_HG-U133A

PIGL COPA INPP4A KDM5C SSX2IP MAPK7 RASAL2

2.61e-061937277187_UP
DrugSB 202190; Down 200; 1uM; PC3; HT_HG-U133A

SMG7 ANK3 COPA INPP4A SPTB SPTBN1 MAPK7

2.79e-061957277058_DN
DrugNaltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; PC3; HT_HG-U133A

ZHX3 SMG7 INPP4A SPTBN1 MYO1F MAPK7 ALDH7A1

2.89e-061967275765_DN
DrugNU1025; Up 200; 100uM; MCF7; HG-U133A

ALLC STARD8 INPP4A SPTB SPTBN1 MYO1F RND2

2.99e-06197727313_UP
DrugSulfameter [651-06-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A

ZHX3 COPA SPTBN1 MYO1F GRB10 GCNT2 MAPK7

3.19e-061997276212_UP
DrugPindolol [13523-86-9]; Down 200; 16.2uM; PC3; HT_HG-U133A

CACTIN COPA INPP4A MYO1F GCNT2 SOX13

3.27e-051927264496_DN
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

ZHX3 PIGL INPP4A SSX2IP GRB10 SOX13

3.37e-051937261667_DN
DrugCarbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A

ZHX3 CACTIN PIGL INPP4A SPTBN1 GRB10

3.47e-051947265342_UP
DrugPropofol [2078-54-8]; Down 200; 22.4uM; HL60; HT_HG-U133A

SMG7 COPA CEP250 SPTBN1 GCNT2 RASAL2

3.57e-051957263048_DN
DrugCyclopenthiazide [742-20-1]; Up 200; 10.6uM; MCF7; HT_HG-U133A

CACTIN ABCA3 SPTBN1 OGDHL MAPK7 SOX13

3.57e-051957264813_UP
DrugMethoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; PC3; HT_HG-U133A

CACTIN TRANK1 SPTBN1 MYO1F MAPK7 ALDH7A1

3.57e-051957266661_DN
Drug2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A

ZHX3 INPP4A SPTBN1 MAPK7 ZHX2 ALDH7A1

3.67e-051967266934_UP
DrugTolfenamic acid [13710-19-5]; Down 200; 15.2uM; PC3; HT_HG-U133A

PIGL COPA INPP4A CEP250 SPTBN1 SSX2IP

3.67e-051967266354_DN
DrugClozapine [5786-21-0]; Down 200; 12.2uM; HL60; HT_HG-U133A

CACTIN PIGL FRY COPA INPP4A SVIL

3.67e-051967261289_DN
DrugGe 3

TMEM132D SPTBN1 ALDH7A1

3.87e-0521723CID000444690
DrugL(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A

ZHX3 PIGL SMG7 SPTBN1 SSX2IP RND2

3.89e-051987266497_DN
DrugBezafibrate [41859-67-0]; Up 200; 11uM; MCF7; HT_HG-U133A

CACTIN MYO1F IRAG2 RND2 GCNT2 ALDH7A1

3.89e-051987264999_UP
DrugRibostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; MCF7; HT_HG-U133A

ZHX3 COPA INPP4A SPTBN1 MYO1F RND2

4.00e-051997263444_UP
DrugAdamantamine fumarate [80789-67-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A

BRAF INPP4A CEP250 OGDHL SOX13 DSN1

4.00e-051997263280_UP
DrugAztreonam [78110-38-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A

CACTIN SMG7 BRAF SCMH1 KDM5C GRB10

4.00e-051997265535_DN
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A

ZHX3 INPP4A SVIL MYO1F GRB10 RND2

4.00e-051997266006_DN
DrugPentylenetetrazole [54-95-5]; Up 200; 29uM; PC3; HT_HG-U133A

ABCA3 INPP4A KDM5C SPTB MAPK7 SOX13

4.00e-051997262092_UP
DrugProcaine hydrochloride [51-05-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A

COPA KDM5C MYO1F GCNT2 MAPK7 RASAL2

4.11e-052007261674_UP
DrugDehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; HL60; HT_HG-U133A

SLC17A9 INPP4A CEP250 SPTBN1 MAPK7 ZHX2

4.11e-052007263097_DN
DrugEU m

ESPL1 ALDH7A1

9.80e-055722CID000205309
DrugAC1L1KMJ

ANK3 SPTB SPTBN1 PEG3 SSX2IP PKD2 MAPK7 CNTN1

1.28e-04476728CID000030956
Drug2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester

DAB2IP STARD8 ANK3 PEG3 SSX2IP FRYL ZHX2 NOS3 CCDC85A RASAL2

2.17e-048077210ctd:C548651
DrugLY 294002; Down 200; 10uM; HL60; HT_HG-U133A

ZHX3 FRY SPTBN1 GRB10 ZHX2

2.87e-041837252696_DN
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

ZHX3 CACTIN FRY SPTB OGDHL

3.02e-041857255935_UP
Drug0175029-0000 [211245-78-2]; Down 200; 1uM; PC3; HT_HG-U133A

CACTIN SSX2IP MAPK7 ESPL1 DSN1

3.33e-041897257392_DN
DrugMeclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A

ZHX3 PIGL INPP4A GRB10 RND2

3.50e-041917253605_DN
DrugRimexolone [49697-38-3]; Up 200; 10.8uM; HL60; HT_HG-U133A

ABCA3 SMG7 INPP4A SPTB SOX13

3.50e-041917252955_UP
DrugMoxalactam disodium salt [64953-12-4]; Down 200; 7uM; HL60; HT_HG-U133A

CACTIN BRAF INPP4A SPTBN1 GRB10

3.67e-041937253028_DN
DrugEthoxyquin [91-53-2]; Down 200; 18.4uM; PC3; HT_HG-U133A

SMG7 ANK3 COPA MAPK7 ALDH7A1

3.67e-041937254321_DN
DrugMethazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A

ZHX3 SPTBN1 DIDO1 SOX13 RASAL2

3.67e-041937253474_UP
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A

CACTIN CEP250 MYO1F PKD2 RND2

3.67e-041937255430_DN
DrugGlycocholic acid [475-31-0]; Down 200; 8.6uM; MCF7; HT_HG-U133A

PIGL SMG7 ANK3 SCMH1 SVIL

3.76e-041947255316_DN
Drugsemustine; Down 200; 100uM; PC3; HT_HG-U133A

INPP4A SPTB SVIL ESPL1 ALDH7A1

3.76e-041947257492_DN
DrugNS-398; Up 200; 10uM; MCF7; HT_HG-U133A

ANK3 COPA INPP4A MYO1F ALDH7A1

3.76e-041947256897_UP
DrugTolfenamic acid [13710-19-5]; Down 200; 15.2uM; MCF7; HT_HG-U133A

CACTIN CEP250 MYO1F GRB10 RND2

3.76e-041947255454_DN
DrugVerteporfin [129497-78-5]; Up 200; 2.8uM; MCF7; HT_HG-U133A

CACTIN INPP4A SPTBN1 MYO1F NOS3

3.76e-041947253556_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 1uM; PC3; HT_HG-U133A

ZHX3 INPP4A SPTB SVIL SOX13

3.76e-041947254291_DN
DrugAndrosterone [53-41-8]; Down 200; 13.8uM; HL60; HT_HG-U133A

ZHX3 CACTIN SMG7 INPP4A SVIL

3.85e-041957251296_DN
DrugHydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; MCF7; HT_HG-U133A

INPP4A GCNT2 SOX13 ALDH7A1 RASAL2

3.85e-041957252283_DN
Drugaspirin, USP; Down 200; 100uM; PC3; HT_HG-U133A

COPA INPP4A SPTB SPTBN1 PEG3

3.85e-041957254428_DN
DrugDiphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; PC3; HT_HG-U133A

ZHX3 ABCA3 PEG3 MYO1F DIDO1

3.85e-041957257318_UP
DrugBenperidol [2062-84-2]; Down 200; 10.4uM; HL60; HT_HG-U133A

CACTIN PIGL TRANK1 SVIL MAPK7

3.85e-041957252475_DN
Drug(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A

ZHX3 SMG7 INPP4A OGDHL MAPK7

3.85e-041957253806_DN
DrugClindamycin hydrochloride [21462-39-5]; Down 200; 8.6uM; MCF7; HT_HG-U133A

ZHX3 CACTIN INPP4A SSX2IP RND2

3.85e-041957257172_DN
DrugMolindone hydrochloride [15622-65-8]; Down 200; 12.8uM; MCF7; HT_HG-U133A

CACTIN PIK3C2B SCMH1 SPTBN1 SVIL

3.85e-041957254784_DN
DrugSB 202190; Up 200; 1uM; MCF7; HT_HG-U133A

STARD8 COPA SPTBN1 SSX2IP MAPK7

3.94e-041967256887_UP
DrugNiflumic acid [4394-00-7]; Down 200; 14.2uM; PC3; HT_HG-U133A

CACTIN ABCA3 INPP4A CEP250 PEG3

3.94e-041967255071_DN
DrugSuxibuzone [27470-51-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A

CACTIN CEP250 GCNT2 MAPK7 CNTN1

3.94e-041967256065_DN
Drugrapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

ZHX3 CACTIN SMG7 BRAF COPA

3.94e-04196725921_DN
DrugIsopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A

ZHX3 SMG7 CEP250 SPTBN1 MAPK7

3.94e-041967253461_UP
DrugHecogenin [467-55-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A

ZHX3 PIGL SMG7 SPTBN1 SSX2IP

3.94e-041967257175_DN
Drugwortmannin from Penicillium funiculosum; Down 200; 0.01uM; PC3; HT_HG-U133A

COPA CEP250 SPTB MAPK7 CNTN1

3.94e-041967254467_DN
DrugDiphenhydramine hydrochloride [147-24-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

PIGL MYO1F MAPK7 ALDH7A1 RASAL2

3.94e-041967251708_UP
DrugHomatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; MCF7; HT_HG-U133A

CACTIN ANK3 KDM5C MAPK7 SOX13

3.94e-041967251684_DN
DrugPhenformin hydrochloride [834-28-6]; Down 200; 16.6uM; MCF7; HT_HG-U133A

ZHX3 COPA CEP250 GRB10 RND2

3.94e-041967254747_DN
DrugMebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Up 200; 4.8uM; HL60; HT_HG-U133A

SMG7 ANK3 PIK3C2B ZHX2 SOX13

3.94e-041967251333_UP
DrugS(+)-Terguride [37686-84-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

CACTIN INPP4A GCNT2 SOX13 RASAL2

4.03e-041977255400_DN
DrugMemantine Hydrochloride [41100-52-1]; Down 200; 18.6uM; MCF7; HT_HG-U133A

ZHX3 CACTIN CEP250 MAPK7 RASAL2

4.03e-041977254135_DN
DrugChenodiol [474-25-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A

ZHX3 CACTIN INPP4A CEP250 ALDH7A1

4.03e-041977256012_DN
DrugCiprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HT_HG-U133A

SMG7 COPA CEP250 SPTBN1 MAPK7

4.03e-041977256700_DN
DrugMerbromin [129-16-8]; Down 200; 5uM; MCF7; HT_HG-U133A

CACTIN SMG7 KDM5C SSX2IP PKD2

4.03e-041977253439_DN
DrugIfenprodil tartrate [23210-58-4]; Down 200; 8.4uM; MCF7; HT_HG-U133A

CACTIN PIGL ANK3 SSX2IP SOX13

4.03e-041977255463_DN
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

KDM5C SPTBN1 MYO1F GCNT2 ALDH7A1

4.03e-041977253894_DN
DrugFlupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A

ZHX3 CACTIN SMG7 SPTBN1 SOX13

4.03e-041977252643_DN
DrugBucladesine sodium salt [16980-89-5]; Down 200; 7.8uM; PC3; HT_HG-U133A

CACTIN SMG7 BRAF CEP250 ZHX2

4.03e-041977255886_DN
DrugEvoxine [522-11-2]; Up 200; 11.6uM; HL60; HT_HG-U133A

ANK3 INPP4A CEP250 PEG3 MAPK7

4.03e-041977252186_UP
DrugLomefloxacin hydrochloride [98079-52-8]; Down 200; 10.4uM; PC3; HT_HG-U133A

ZHX3 SMG7 SVIL ALDH7A1 RASAL2

4.03e-041977253723_DN
DrugAntipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; MCF7; HT_HG-U133A

CACTIN SMG7 SCMH1 RND2 SOX13

4.03e-041977251497_DN
DrugNimodipine [66085-59-4]; Down 200; 9.6uM; PC3; HT_HG-U133A

CACTIN SMG7 KDM5C MAPK7 ALDH7A1

4.03e-041977256320_DN
DrugFosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A

ANK3 CEP250 SPTBN1 GRB10 CNTN1

4.03e-041977253336_DN
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A

ZHX3 KDM5C GRB10 RND2 RASAL2

4.03e-041977255576_DN
DrugSulfachloropyridazine [80-32-0]; Up 200; 14uM; MCF7; HT_HG-U133A

ALLC TRANK1 INPP4A CEP250 MAPK7

4.03e-041977256046_UP
DrugPridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; MCF7; HT_HG-U133A

SCMH1 INPP4A SPTBN1 GRB10 GCNT2

4.03e-041977253456_DN
DrugCloxacillin sodium salt [642-78-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A

CACTIN PIGL BRAF INPP4A MYO1F

4.03e-041977257483_DN
DrugPyridoxine hydrochloride [58-56-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A

PIGL ABCA3 PKD2 RND2 SOX13

4.03e-041977257171_DN
DrugAlfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A

CACTIN SPTB RND2 MAPK7 CNTN1

4.03e-041977255605_UP
DrugQuipazine dimaleate salt [4774-24-7]; Down 200; 9uM; MCF7; HT_HG-U133A

CACTIN INPP4A KDM5C MYO1F SOX13

4.03e-041977252782_DN
DrugDeferoxamine mesylate [138-14-7]; Down 200; 6uM; MCF7; HT_HG-U133A

CACTIN SMG7 SVIL SSX2IP GRB10

4.03e-041977253417_DN
DrugPicotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A

CACTIN BRAF DIDO1 FRYL MAPK7

4.03e-041977252070_DN
Drug2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A

CACTIN BRAF KDM5C PKD2 DIDO1

4.03e-041977256974_DN
DrugCarteolol hydrochloride [51781-21-6]; Up 200; 12.2uM; MCF7; HT_HG-U133A

INPP4A CEP250 MAPK7 SOX13 DSN1

4.13e-041987253276_UP
Drugnovobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A

ANK3 INPP4A SSX2IP GRB10 DSN1

4.13e-04198725437_UP
Drug5155877; Down 200; 10uM; PC3; HT_HG-U133A

PIGL SMG7 INPP4A CEP250 SOX13

4.13e-041987256544_DN
DrugParomomycin sulfate [1263-89-4]; Down 200; 5.6uM; MCF7; HT_HG-U133A

ZHX3 GRB10 GCNT2 MAPK7 CNTN1

4.13e-041987253356_DN
DrugNitrendipine [39562-70-4]; Down 200; 11uM; HL60; HT_HG-U133A

SLC17A9 PIK3C2B INPP4A SSX2IP MAPK7

4.13e-041987253087_DN
DrugCefuroxime sodium salt [56238-63-2]; Up 200; 9uM; HL60; HT_HG-U133A

TRANK1 ANK3 SPTBN1 GCNT2 CNTN1

4.13e-041987252526_UP
DrugSulfadimethoxine [122-11-2]; Down 200; 12.8uM; MCF7; HT_HG-U133A

SMG7 INPP4A MYO1F GRB10 SOX13

4.13e-041987253441_DN
DrugQuipazine dimaleate salt [4774-24-7]; Down 200; 9uM; MCF7; HT_HG-U133A

BRAF PIK3C2B SVIL GRB10 SOX13

4.13e-041987257240_DN
DrugPNU-0230031 [267429-39-0]; Down 200; 1uM; MCF7; HT_HG-U133A

KDM5C SPTB MYO1F ALDH7A1 RASAL2

4.13e-041987253632_DN
DrugDiazoxide [364-98-7]; Down 200; 17.4uM; MCF7; HT_HG-U133A

ZHX3 INPP4A KDM5C SVIL SOX13

4.13e-041987257168_DN
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A

ABCA3 INPP4A MAPK7 ALDH7A1 CNTN1

4.13e-041987253286_UP
DrugCinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

ZHX3 INPP4A KDM5C MAPK7 SOX13

4.13e-041987253175_DN
DrugPergolide mesylate [66104-23-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A

SMG7 SCMH1 INPP4A CEP250 SSX2IP

4.13e-041987257031_DN
DrugSulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A

COPA KDM5C DIDO1 MAPK7 RASAL2

4.13e-041987254979_DN
DrugConvolamine hydrochloride [500-56-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

ZHX3 CACTIN INPP4A SPTBN1 MYO1F

4.13e-041987255876_UP
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTB SPTBN1

3.41e-054712DOID:0050882 (implicated_via_orthology)
Diseasevulva cancer (is_implicated_in)

HLA-DRB1 NOS3

3.41e-054712DOID:1245 (is_implicated_in)
Diseaseextranodal nasal NK/T cell lymphoma

HLA-DRB1 HLA-DRB3

8.51e-056712MONDO_0019472
Diseaseretinopathy of prematurity (is_implicated_in)

HLA-DRB1 NOS3

1.19e-047712DOID:13025 (is_implicated_in)
Diseasehydroxy-leucine measurement

DAB2IP TTLL11 CNTN1

1.76e-0445713EFO_0005276
Diseaseresponse to vaccine

HLA-DRB1 HLA-DRB3 ZHX2 RASAL2

2.18e-04122714EFO_0004645
Diseaseaspirin-induced respiratory disease (is_implicated_in)

HLA-DRB1 HLA-DRB3

3.10e-0411712DOID:0080822 (is_implicated_in)
DiseaseOligospermia

NOS3 PIWIL3

3.71e-0412712C0028960
Diseasetemporal arteritis

RSBN1 HLA-DRB1

3.71e-0412712EFO_1001209
Diseasemigraine disorder, type 2 diabetes mellitus

ZHX3 FRYL KIAA2012

4.14e-0460713MONDO_0005148, MONDO_0005277
Diseasebipolar disorder

TRANK1 ANK3 BRAF INPP4A ACTN3 RASAL2 CNTN1

4.75e-04577717MONDO_0004985
Diseaserheumatoid arthritis, COVID-19

RSBN1 HLA-DRB1 FRYL

5.01e-0464713EFO_0000685, MONDO_0100096
Diseasehearing loss

HLA-DRB1 SPTBN1 GRB10

5.73e-0467713EFO_0004238
Diseasecleft lip

FRY TMEM132D HLA-DRB3 SVIL CCDC85A

6.18e-04284715EFO_0003959
Diseasegout, hyperuricemia

MALRD1 PKD2

6.70e-0416712EFO_0004274, EFO_0009104
Diseasemean platelet volume

RSBN1 FRY TRANK1 STARD8 SPTBN1 SVIL FRYL ESPL1 NOS3

7.41e-041020719EFO_0004584
Diseasehepatocellular carcinoma (is_marker_for)

DAB2IP KDM5C NLRC5 DSN1 ALDH7A1

8.03e-04301715DOID:684 (is_marker_for)
DiseaseManic

TRANK1 ANK3 DNAH8

8.92e-0478713C0338831
Diseasehepatitis B virus infection

HLA-DRB1 HLA-DRB3

9.51e-0419712EFO_0004197
Diseaseleptin measurement

HLA-DRB1 SPTB DNAH8

9.96e-0481713EFO_0005000
Diseasediastolic blood pressure, systolic blood pressure

PIGL MALRD1 ANK3 SLC7A6OS SVIL SCYL1 GRB10

1.14e-03670717EFO_0006335, EFO_0006336
DiseaseImmunosuppressant use measurement

RSBN1 HLA-DRB1

1.16e-0321712EFO_0009934
DiseaseHenoch-Schoenlein purpura

MALRD1 HLA-DRB1

1.28e-0322712EFO_1000965
DiseaseLymphoma, Non-Hodgkin, Familial

BRAF HLA-DRB1

1.28e-0322712C4721532
DiseaseColorectal Carcinoma

ABCA3 STARD8 BRAF PEG3 DNAH8 RASAL2 CNTN1

1.49e-03702717C0009402
DiseaseCholangiocarcinoma

BRAF PEG3

1.79e-0326712C0206698

Protein segments in the cluster

PeptideGeneStartEntry
NRMKTLGRRDSSDDW

BRAF

436

P15056
DSQRNKERTRFTWMD

LINC00242

71

Q5T6M2
LWRADDVSRHEKMGS

ANKRD18A

446

Q8IVF6
EQMRSKGNRDRPWSN

CDC42SE1

61

Q9NRR8
RESGSDAWKQYMRRS

ALDH7A1

506

P49419
GAKSMADGWETARRL

ALLC

226

Q8N6M5
SWRTGKTEARNEDEM

SSX2IP

241

Q9Y2D8
DKWNSRSRFLSGGMR

ABCA3

656

Q99758
LRVLSSWREDSMDRK

CST9

71

Q5W186
DQDTLMARWTGRNSR

INPP4A

501

Q96PE3
SAAERDKWMENLRRA

DAB2IP

186

Q5VWQ8
LSDNDRSLLERWTRM

MAPK7

561

Q13164
GNLRAIKWSDMEDRH

GCNT2

321

Q8N0V5
LRGRADMTKNRTVDW

OGDHL

626

Q9ULD0
DGAAWDRRNGKLMES

DNAH8

4406

Q96JB1
ESMDNFNWGVRRRSL

FRYL

2441

O94915
NSASERDKWMENLRR

RASAL2

141

Q9UJF2
EKASWDRLRAERAEM

KIAA2012

981

Q0VF49
DRRREWAALGNMSKE

ACBD3

141

Q9H3P7
DTRQASNRWEKRAME

DNAJC21

171

Q5F1R6
DRSQRFPRMSDDNWK

PEG3

336

Q9GZU2
LRGDKTSRDMWATGS

NLRC5

1076

Q86WI3
WRRKRKESSNTDSAG

NOS3

626

P29474
AEMLRDATRGWKEGR

PIK3C2B

246

O00750
RGDKAHFRSTMWRES

MALRD1

1576

Q5VYJ5
EWRARSESAQSKMLS

HLA-DRB3

216

P79483
NWRKMSFEILRGSDG

ESPL1

1496

Q14674
SESRSGRVEMRKWSS

KLHL11

131

Q9NVR0
MAKNRRDRNSWGGFS

ATL1

1

Q8WXF7
WDMSKRTGVQTFRRD

COPA

276

P53621
KWRMNNGDVDLTSDR

CNTN1

76

Q12860
SRARDELMRKESQWQ

CEP250

146

Q9BV73
DRRQSWRRASMKETN

DSN1

91

Q9H410
KDSSRDWDRNRERSA

DIDO1

2141

Q9BTC0
EWRARSESAQSKMLS

HLA-DRB1

216

P01911
WMRFTEDRLDRGREK

ANK3

2556

Q12955
NSSNMEKGWGSRARR

CCDC85A

451

Q96PX6
GMENNDRFSRRSSSW

IRAG2

391

Q12912
LEEGHAWRKRSTRMN

GRB10

456

Q13322
RSDSEEERWQRSGMR

CACTIN

56

Q8WUQ7
RDKMRKWREENSRNS

EMC2

16

Q15006
MDNFNWGVRRRSLDS

FRY

2476

Q5TBA9
RSMKGLRWEDTRDTA

DNAJC30

196

Q96LL9
RRMVKANSQGDWSRE

PIWIL3

481

Q7Z3Z3
TDWADRDNGEMRRKT

NLGN2

436

Q8NFZ4
MFISGRRTADKWRAE

RSBN1

1

Q5VWQ0
SARIRWASDRKSAME

SVIL

2071

O95425
IMGRDWDDRSAGEKL

TMEM132D

151

Q14C87
DSSGRVVREKWSADM

SCYL1

191

Q96KG9
VWDSSERMKSREQGG

PIGL

21

Q9Y2B2
DNRDRRTADRWKTDK

SMG7

1036

Q92540
GDKAEWRTMRQTFRA

STRIP1

236

Q5VSL9
DEARRDMAGDTQWSR

SLC17A9

6

Q9BYT1
DLLRDAAERFKGWMS

STARD8

826

Q92502
VLKGSNERRDMESFW

SCMH1

551

Q96GD3
NERRDMESFWKLNRS

SCMH1

556

Q96GD3
RFDRKAAMRETWLSE

SPTBN1

426

Q01082
EAWTRGKEEMLSQRD

ACTN3

421

Q08043
EEERGSSRQRMWSKY

SLC7A6OS

276

Q96CW6
DKRRIELNMWDTSGS

RND2

51

P52198
AWTKRNDMRLDSEGI

TRIM77

361

I1YAP6
MRRGSSESELAARWE

TTLL11

91

Q8NHH1
SDWKERFLGRNSMEA

SOX13

121

Q9UN79
ASQMRESWRHKAGRR

ZSCAN5DP

31

P0CG00
RRKGSKWNRRNDMGE

TONSL

516

Q96HA7
RNKDGSQSGSRMEDW

ZNF521

226

Q96K83
RFDRKAAMRETWLSE

SPTB

426

P11277
WGTRLMEESSTNREK

PKD2

201

Q13563
WFSERRKLRDSMEQA

ZHX2

576

Q9Y6X8
DSRQLASGGWDKRVM

WDR38

116

Q5JTN6
ARNRRESTDLWLSAM

TRANK1

2276

O15050
RSETKMTRREIDSWF

ZHX3

646

Q9H4I2
MTRREIDSWFSERRK

ZHX3

651

Q9H4I2
LTDGANRSWLGRKMS

WDR87

861

Q6ZQQ6
ADAGSDSTKRSRWME

KDM5C

1106

P41229
LTSRKMDSRWGGRSE

MYO1F

321

O00160