Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	helicase activity	MCM8 MOV10L1 WRN DDX53 DDX43 DDX4 DDX3X	3.62e-06	158	81	7	GO:0004386
GeneOntologyMolecularFunction	mismatch repair complex binding	MCM8 WRN PCNA	1.04e-05	11	81	3	GO:0032404
GeneOntologyMolecularFunction	RNA helicase activity	MOV10L1 DDX53 DDX43 DDX4 DDX3X	1.62e-05	78	81	5	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	MOV10L1 DDX53 DDX43 DDX4 DDX3X	1.84e-05	80	81	5	GO:0008186
GeneOntologyMolecularFunction	ATP hydrolysis activity	MCM8 MOV10L1 WRN ABCC9 DDX53 DDX43 DYNC1H1 DDX4 DDX3X	7.36e-05	441	81	9	GO:0016887
GeneOntologyMolecularFunction	beta-adrenergic receptor kinase activity	GRK2 GRK3	9.70e-05	4	81	2	GO:0047696
GeneOntologyMolecularFunction	histone binding	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.01e-04	265	81	7	GO:0042393
GeneOntologyMolecularFunction	ATP-dependent activity	IPO8 MCM8 MOV10L1 WRN ABCC9 DDX53 DDX43 DYNC1H1 DDX4 DDX3X	1.85e-04	614	81	10	GO:0140657
GeneOntologyMolecularFunction	chromatin binding	SF3B1 MCM8 WRN TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 PCNA	1.90e-04	739	81	11	GO:0003682
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	RNASE11 MCM8 MOV10L1 WRN DDX53 DDX43 DDX4 DDX3X PCNA METTL14	2.75e-04	645	81	10	GO:0140640
GeneOntologyMolecularFunction	G protein-coupled receptor kinase activity	GRK2 GRK3	3.37e-04	7	81	2	GO:0004703
GeneOntologyMolecularFunction	MutLalpha complex binding	WRN PCNA	3.37e-04	7	81	2	GO:0032405
GeneOntologyMolecularFunction	mRNA binding	TDRD7 SF3B1 KHDRBS3 KHDRBS2 RBM42 DDX53 DDX43 DDX4 DDX3X METTL14	4.89e-04	694	81	10	GO:0003729
GeneOntologyMolecularFunction	catalytic activity, acting on RNA	RNASE11 MOV10L1 DDX53 DDX43 DDX4 DDX3X METTL14	1.52e-03	417	81	7	GO:0140098
GeneOntologyMolecularFunction	DNA helicase activity	MCM8 WRN DDX3X	2.05e-03	62	81	3	GO:0003678
GeneOntologyBiologicalProcess	gonadal mesoderm development	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	3.29e-16	9	79	7	GO:0007506
GeneOntologyBiologicalProcess	nucleosome assembly	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	4.34e-07	122	79	7	GO:0006334
GeneOntologyBiologicalProcess	male gamete generation	TDRD7 ADGB MCM8 MOV10L1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 DDX4 DDX3X METTL14	1.05e-06	762	79	14	GO:0048232
GeneOntologyBiologicalProcess	nucleosome organization	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.21e-06	142	79	7	GO:0034728
GeneOntologyBiologicalProcess	multicellular organismal reproductive process	TDRD7 ADGB GRK2 MCM8 KALRN MOV10L1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 DDX4 DDX3X PCNA METTL14	2.16e-06	1194	79	17	GO:0048609
GeneOntologyBiologicalProcess	mesoderm development	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	2.37e-06	157	79	7	GO:0007498
GeneOntologyBiologicalProcess	spermatogenesis	TDRD7 ADGB MOV10L1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 DDX4 DDX3X METTL14	4.63e-06	744	79	13	GO:0007283
GeneOntologyBiologicalProcess	gonad development	GRK2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.60e-05	292	79	8	GO:0008406
GeneOntologyBiologicalProcess	development of primary sexual characteristics	GRK2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.81e-05	297	79	8	GO:0045137
GeneOntologyBiologicalProcess	gamete generation	TDRD7 ADGB MCM8 MOV10L1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 DDX4 DDX3X METTL14	1.93e-05	982	79	14	GO:0007276
GeneOntologyBiologicalProcess	protein-DNA complex assembly	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	4.75e-05	249	79	7	GO:0065004
GeneOntologyBiologicalProcess	sex differentiation	GRK2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	6.04e-05	352	79	8	GO:0007548
GeneOntologyBiologicalProcess	piRNA processing	TDRD7 MOV10L1 DDX4	7.90e-05	22	79	3	GO:0034587
GeneOntologyBiologicalProcess	reproductive structure development	GRK2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.09e-04	383	79	8	GO:0048608
GeneOntologyBiologicalProcess	reproductive system development	GRK2 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.19e-04	388	79	8	GO:0061458
GeneOntologyBiologicalProcess	sexual reproduction	TDRD7 ADGB MCM8 MOV10L1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 SERPINA10 TSPY8 TSPY1 DDX4 DDX3X METTL14	1.19e-04	1312	79	15	GO:0019953
GeneOntologyBiologicalProcess	RNA splicing	WBP11 SF3B1 KHDRBS3 KHDRBS2 RBM42 SF3A3 VIRMA RBM39 METTL14	1.27e-04	502	79	9	GO:0008380
GeneOntologyBiologicalProcess	regulatory ncRNA processing	TDRD7 MOV10L1 DDX4 DDX3X	1.87e-04	74	79	4	GO:0070918
GeneOntologyBiologicalProcess	developmental process involved in reproduction	TDRD7 ADGB GRK2 MOV10L1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 DDX4 DDX3X METTL14	2.26e-04	1235	79	14	GO:0003006
GeneOntologyBiologicalProcess	mRNA processing	WBP11 SF3B1 KHDRBS3 KHDRBS2 RBM42 SF3A3 VIRMA RBM39 METTL14	2.54e-04	551	79	9	GO:0006397
GeneOntologyBiologicalProcess	mRNA splicing, via spliceosome	SF3B1 KHDRBS3 KHDRBS2 RBM42 SF3A3 RBM39 METTL14	4.44e-04	358	79	7	GO:0000398
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	SF3B1 KHDRBS3 KHDRBS2 RBM42 SF3A3 RBM39 METTL14	4.44e-04	358	79	7	GO:0000377
GeneOntologyBiologicalProcess	RNA splicing, via transesterification reactions	SF3B1 KHDRBS3 KHDRBS2 RBM42 SF3A3 RBM39 METTL14	4.75e-04	362	79	7	GO:0000375
GeneOntologyBiologicalProcess	cellular response to nutrient levels	PHEX PIK3C2B TBC1D7 WRN VPS41 JMY	5.08e-04	262	79	6	GO:0031669
GeneOntologyBiologicalProcess	telomere maintenance via semi-conservative replication	WRN PCNA	5.12e-04	9	79	2	GO:0032201
GeneOntologyBiologicalProcess	chromatin remodeling	SF3B1 MOV10L1 TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1 DDX4	5.18e-04	741	79	10	GO:0006338
GeneOntologyBiologicalProcess	mesenchyme development	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	5.58e-04	372	79	7	GO:0060485
GeneOntologyBiologicalProcess	chromatin organization	SF3B1 MOV10L1 TSPY4 TSPY3 TSPY10 LAMC1 TSPY2 TSPY9 TSPY8 TSPY1 DDX4	5.93e-04	896	79	11	GO:0006325
GeneOntologyBiologicalProcess	regulation of mitotic spindle organization	CHMP4A DCTN1 DYNC1H1	6.40e-04	44	79	3	GO:0060236
GeneOntologyBiologicalProcess	cellular response to starvation	PIK3C2B TBC1D7 WRN VPS41 JMY	7.25e-04	185	79	5	GO:0009267
GeneOntologyBiologicalProcess	base-excision repair	WRN PCNA USP47	7.29e-04	46	79	3	GO:0006284
GeneOntologyBiologicalProcess	siRNA-mediated heterochromatin formation	MOV10L1 DDX4	7.79e-04	11	79	2	GO:0141194
GeneOntologyBiologicalProcess	transposable element silencing by siRNA-mediated heterochromatin formation	MOV10L1 DDX4	7.79e-04	11	79	2	GO:0141007
GeneOntologyBiologicalProcess	regulation of spindle organization	CHMP4A DCTN1 DYNC1H1	8.26e-04	48	79	3	GO:0090224
GeneOntologyCellularComponent	pole plasm	TDRD7 MOV10L1 DDX4 DDX3X	4.39e-06	29	80	4	GO:0045495
GeneOntologyCellularComponent	germ plasm	TDRD7 MOV10L1 DDX4 DDX3X	4.39e-06	29	80	4	GO:0060293
GeneOntologyCellularComponent	P granule	TDRD7 MOV10L1 DDX4 DDX3X	4.39e-06	29	80	4	GO:0043186
GeneOntologyCellularComponent	RNA N6-methyladenosine methyltransferase complex	VIRMA METTL14	5.12e-04	9	80	2	GO:0036396
GeneOntologyCellularComponent	pi-body	MOV10L1 DDX4	7.78e-04	11	80	2	GO:0071546
GeneOntologyCellularComponent	neuron to neuron synapse	GRK2 GRK3 MAP1B KALRN RNF19A DBNL DVL1 MAPK10	8.70e-04	523	80	8	GO:0098984
Domain	NAP	TSPY4 TSPY10 TSPY2 TSPY8	6.10e-07	17	77	4	PF00956
Domain	NAP_family	TSPY4 TSPY10 TSPY2 TSPY8	6.10e-07	17	77	4	IPR002164
Domain	DEAD_ATP_HELICASE	DDX53 DDX43 DDX4 DDX3X	7.72e-06	31	77	4	PS00039
Domain	RNA-helicase_DEAD-box_CS	DDX53 DDX43 DDX4 DDX3X	9.98e-06	33	77	4	IPR000629
Domain	DEAD/DEAH_box_helicase_dom	WRN DDX53 DDX43 DDX4 DDX3X	1.26e-05	73	77	5	IPR011545
Domain	DEAD	WRN DDX53 DDX43 DDX4 DDX3X	1.26e-05	73	77	5	PF00270
Domain	Q_MOTIF	DDX53 DDX43 DDX4 DDX3X	1.59e-05	37	77	4	PS51195
Domain	RNA_helicase_DEAD_Q_motif	DDX53 DDX43 DDX4 DDX3X	1.59e-05	37	77	4	IPR014014
Domain	DVL-1	DVL1P1 DVL1	1.68e-05	2	77	2	IPR008340
Domain	KH_1	KHDRBS3 KHDRBS2 DDX53 DDX43	1.77e-05	38	77	4	PF00013
Domain	-	KHDRBS3 KHDRBS2 DDX53 DDX43	1.97e-05	39	77	4	3.30.1370.10
Domain	KH	KHDRBS3 KHDRBS2 DDX53 DDX43	2.18e-05	40	77	4	SM00322
Domain	KH_dom	KHDRBS3 KHDRBS2 DDX53 DDX43	2.18e-05	40	77	4	IPR004087
Domain	KH_TYPE_1	KHDRBS3 KHDRBS2 DDX53 DDX43	2.65e-05	42	77	4	PS50084
Domain	KH_dom_type_1	KHDRBS3 KHDRBS2 DDX53 DDX43	3.20e-05	44	77	4	IPR004088
Domain	Qua1	KHDRBS3 KHDRBS2	5.02e-05	3	77	2	PF16274
Domain	Qua1_dom	KHDRBS3 KHDRBS2	5.02e-05	3	77	2	IPR032571
Domain	Sam68-YY	KHDRBS3 KHDRBS2	5.02e-05	3	77	2	IPR032335
Domain	Sam68-YY	KHDRBS3 KHDRBS2	5.02e-05	3	77	2	PF16568
Domain	Helicase_C	WRN DDX53 DDX43 DDX4 DDX3X	8.00e-05	107	77	5	PF00271
Domain	HELICc	WRN DDX53 DDX43 DDX4 DDX3X	8.00e-05	107	77	5	SM00490
Domain	Helicase_C	WRN DDX53 DDX43 DDX4 DDX3X	8.36e-05	108	77	5	IPR001650
Domain	HELICASE_CTER	WRN DDX53 DDX43 DDX4 DDX3X	8.73e-05	109	77	5	PS51194
Domain	HELICASE_ATP_BIND_1	WRN DDX53 DDX43 DDX4 DDX3X	8.73e-05	109	77	5	PS51192
Domain	DEXDc	WRN DDX53 DDX43 DDX4 DDX3X	8.73e-05	109	77	5	SM00487
Domain	Helicase_ATP-bd	WRN DDX53 DDX43 DDX4 DDX3X	9.12e-05	110	77	5	IPR014001
Domain	Dishevelled_fam	DVL1P1 DVL1	1.00e-04	4	77	2	IPR008339
Domain	Dishevelled	DVL1P1 DVL1	1.00e-04	4	77	2	PF02377
Domain	Dishevelled_protein_dom	DVL1P1 DVL1	1.00e-04	4	77	2	IPR003351
Domain	GPCR_kinase	GRK2 GRK3	3.48e-04	7	77	2	IPR000239
Domain	DIX	DVL1P1 DVL1	3.48e-04	7	77	2	PF00778
Domain	DIX	DVL1P1 DVL1	3.48e-04	7	77	2	IPR001158
Domain	DIX	DVL1P1 DVL1	3.48e-04	7	77	2	PS50841
Domain	DAX	DVL1P1 DVL1	3.48e-04	7	77	2	SM00021
Domain	EF-hand-dom_pair	TBC1D8 PPP2R3A STIM2 NUCB1 PLCL2 NUCB2	1.19e-03	287	77	6	IPR011992
Domain	ARM-type_fold	SF3B1 IPO8 PIK3C2B UBR4 XPO4 VIRMA	2.75e-03	339	77	6	IPR016024
Domain	-	MCM8 MOV10L1 WRN ABCC9 DDX53 DDX43 DYNC1H1 DDX4 DDX3X	3.51e-03	746	77	9	3.40.50.300
Domain	DEP	DVL1P1 DVL1	3.67e-03	22	77	2	PF00610
Domain	DEP	DVL1P1 DVL1	3.67e-03	22	77	2	PS50186
Domain	DEP	DVL1P1 DVL1	3.67e-03	22	77	2	SM00049
Domain	DEP_dom	DVL1P1 DVL1	4.01e-03	23	77	2	IPR000591
Domain	-	TBC1D8 PPP2R3A NUCB1 PLCL2 NUCB2	4.47e-03	261	77	5	1.10.238.10
Pathway	WP_MRNA_PROCESSING	TDRD7 SF3B1 RBM42 SF3A3 VIRMA RBM39 DDX4 CFB DDX3X	9.84e-05	451	59	9	MM15946
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	WBP11 SF3B1 RBM42 SF3A3 NUP160 RBM39 METTL14	1.49e-04	277	59	7	MM15414
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	WBP11 SF3B1 RBM42 SF3A3 NUP160 RBM39 METTL14	1.70e-04	283	59	7	M13087
Pathway	REACTOME_PTK6_REGULATES_PROTEINS_INVOLVED_IN_RNA_PROCESSING	KHDRBS3 KHDRBS2	1.71e-04	5	59	2	M27731
Pathway	REACTOME_PTK6_REGULATES_PROTEINS_INVOLVED_IN_RNA_PROCESSING	KHDRBS3 KHDRBS2	1.71e-04	5	59	2	MM15481
Pubmed	R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.	WBP11 SF3B1 MAP1B TBC1D7 UBR4 RBM42 SF3A3 RBM39	6.29e-07	300	83	8	28561026
Pubmed	Identification of phosphoproteins and their phosphorylation sites in the WEHI-231 B lymphoma cell line.	WBP11 SF3B1 GRK2 RBM39 DDX3X	1.34e-06	79	83	5	14729942
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	SF3B1 KHDRBS3 MAP1B ACBD5 DYNC1H1 DDX3X USP47	1.45e-06	232	83	7	25515538
Pubmed	The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.	GRK2 GRK3 KHDRBS3 KHDRBS2 DYNC1H1	2.05e-06	86	83	5	26885983
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	WBP11 SF3B1 IPO8 MAP1B UBR4 LPP SF3A3 LAMC1 COPS3 DCTN1 NUP160 RBM39 DDX3X PCNA	4.11e-06	1367	83	14	32687490
Pubmed	Cloning of GRK2 cDNA from S49 murine lymphoma cells.	GRK2 GRK3	5.63e-06	2	83	2	8638670
Pubmed	Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.	GRK2 GRK3	5.63e-06	2	83	2	33060647
Pubmed	G Protein binding sites on Calnuc (nucleobindin 1) and NUCB2 (nucleobindin 2) define a new class of G(alpha)i-regulatory motifs.	NUCB1 NUCB2	5.63e-06	2	83	2	21653697
Pubmed	G protein--coupled receptor kinases.	GRK2 GRK3	5.63e-06	2	83	2	8035170
Pubmed	Alternative splicing coupled nonsense-mediated decay generates neuronal cell type-specific expression of SLM proteins.	KHDRBS3 KHDRBS2	5.63e-06	2	83	2	25505328
Pubmed	An Exceptional Gene: Evolution of the TSPY Gene Family in Humans and Other Great Apes.	TSPY9 TSPY1	5.63e-06	2	83	2	24710137
Pubmed	Cancer-relevant splicing factor CAPERα engages the essential splicing factor SF3b155 in a specific ternary complex.	SF3B1 RBM39	5.63e-06	2	83	2	24795046
Pubmed	Structure and function of TSPY, the Y-chromosome gene coding for the "testis-specific protein".	TSPY9 TSPY1	5.63e-06	2	83	2	9678360
Pubmed	Battle of the sexes: contrasting roles of testis-specific protein Y-encoded (TSPY) and TSPX in human oncogenesis.	TSPY9 TSPY1	5.63e-06	2	83	2	29974883
Pubmed	Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.	GRK2 GRK3	5.63e-06	2	83	2	10198406
Pubmed	Characterisation of the interaction between WRN, the helicase/exonuclease defective in progeroid Werner's syndrome, and an essential replication factor, PCNA.	WRN PCNA	5.63e-06	2	83	2	12633936
Pubmed	PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration.	PPP2R3A LPP	5.63e-06	2	83	2	26945059
Pubmed	Characterization of the human and mouse WRN 3'-->5' exonuclease.	WRN PCNA	5.63e-06	2	83	2	10871373
Pubmed	TSPY, the candidate gonadoblastoma gene on the human Y chromosome, has a widely expressed homologue on the X - implications for Y chromosome evolution.	TSPY9 TSPY1	5.63e-06	2	83	2	15241014
Pubmed	G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.	GRK2 GRK3	5.63e-06	2	83	2	11762794
Pubmed	TSPY-related sequences represent a microheterogeneous gene family organized as constitutive elements in DYZ5 tandem repeat units on the human Y chromosome.	TSPY9 TSPY1	5.63e-06	2	83	2	8244388
Pubmed	Dynactin functions as both a dynamic tether and brake during dynein-driven motility.	DCTN1 DYNC1H1	5.63e-06	2	83	2	25185702
Pubmed	Dynein drives nuclear rotation during forward progression of motile fibroblasts.	DCTN1 DYNC1H1	5.63e-06	2	83	2	18782860
Pubmed	Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.	DVL1P1 DVL1	5.63e-06	2	83	2	8644734
Pubmed	Calnuc binds to Alzheimer's beta-amyloid precursor protein and affects its biogenesis.	NUCB1 NUCB2	5.63e-06	2	83	2	17348862
Pubmed	Modulation of nucleobindin-1 and nucleobindin-2 by caspases.	NUCB1 NUCB2	5.63e-06	2	83	2	18154733
Pubmed	Low dietary protein content alleviates motor symptoms in mice with mutant dynactin/dynein-mediated neurodegeneration.	DCTN1 DYNC1H1	5.63e-06	2	83	2	25552654
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDR2 STIM2 MAP1B PIK3C2B CEP89 LPP DBNL MAP3K20 LAMC1 VIRMA DDX3X	6.40e-06	861	83	11	36931259
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	SF3B1 IPO8 KHDRBS3 MAP1B UBR4 SF3A3 RBM39 DDX3X PCNA	6.84e-06	551	83	9	34728620
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PHEX WBP11 STIM2 SF3B1 KHDRBS3 MAP1B UBR4 NUCB1 DBNL KHDRBS2 NUCB2 RBM42 DCTN1 KIAA2012	7.56e-06	1442	83	14	35575683
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	TDRD7 CDR2 KHDRBS3 CEP89 NUCB1 DBNL LAMC1 MAPK10 DCTN1	7.79e-06	560	83	9	21653829
Pubmed	Dynamic protein-protein interaction wiring of the human spliceosome.	WBP11 SF3B1 KHDRBS3 RBM42 SF3A3 RBM39	8.04e-06	197	83	6	22365833
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	UBR4 RBM42 SF3A3 RBM39 DYNC1H1 DDX3X	1.04e-05	206	83	6	22174317
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TBC1D8 WBP11 C5orf34 STIM2 PLOD3 SF3B1 IPO8 CEP89 UBR4 NUCB1 ACBD5 NUCB2 LAMC1 DCTN1	1.07e-05	1487	83	14	33957083
Pubmed	Functional proteomics mapping of a human signaling pathway.	STIM2 SF3B1 UBR4 PLCL2 VPS41 LAMC1 DCTN1 DYNC1H1 DDX3X	1.20e-05	591	83	9	15231748
Pubmed	Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.	GRK2 GRK3	1.69e-05	3	83	2	10754297
Pubmed	Disruption of the dynein-dynactin complex unveils motor-specific functions in osteoclast formation and bone resorption.	DCTN1 DYNC1H1	1.69e-05	3	83	2	22887640
Pubmed	Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.	GRK2 GRK3	1.69e-05	3	83	2	10085131
Pubmed	Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.	GRK2 GRK3	1.69e-05	3	83	2	7761854
Pubmed	The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.	GRK2 GRK3	1.69e-05	3	83	2	31604529
Pubmed	Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.	GRK2 GRK3	1.69e-05	3	83	2	12130708
Pubmed	Identification of a small molecule splicing inhibitor targeting UHM domains.	SF3B1 RBM39	1.69e-05	3	83	2	34520118
Pubmed	Preferentially localized dynein and perinuclear dynactin associate with nuclear pore complex proteins to mediate genomic union during mammalian fertilization.	DCTN1 DYNC1H1	1.69e-05	3	83	2	14600259
Pubmed	Deep sequencing identifies genetic heterogeneity and recurrent convergent evolution in chronic lymphocytic leukemia.	SF3B1 DDX3X	1.69e-05	3	83	2	25377784
Pubmed	SAM68-Specific Splicing Is Required for Proper Selection of Alternative 3' UTR Isoforms in the Nervous System.	KHDRBS3 KHDRBS2	1.69e-05	3	83	2	31805436
Pubmed	[Functional Hypermethylation of ALDH1L1, PLCL2, and PPP2R3A in Colon Cancer].	PPP2R3A PLCL2	1.69e-05	3	83	2	32392189
Pubmed	U2AF65 assemblies drive sequence-specific splice site recognition.	SF3B1 RBM39	1.69e-05	3	83	2	31271494
Pubmed	Inhibition of HIV-1 gene expression by Sam68 Delta C: multiple targets but a common mechanism?	KHDRBS3 KHDRBS2	1.69e-05	3	83	2	19254361
Pubmed	A DEAD-family protein gene, Ddx4, encoding a murine homolog of Drosophila vasa maps to the distal end of mouse chromosome 13.	MAP1B DDX4	1.69e-05	3	83	2	9250878
Pubmed	Mapping of determinants involved in the stimulation of HIV-1 expression by Sam68.	KHDRBS3 KHDRBS2	1.69e-05	3	83	2	19091369
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SF3B1 MAP1B UBR4 DBNL MAP3K20 SF3A3 COPS3 DDX43 DCTN1 NUP160 RBM39 DYNC1H1 PCNA	1.85e-05	1353	83	13	29467282
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	SF3B1 GRK2 MAP1B UBR4 NUCB1 DYNC1H1 PCNA	1.90e-05	344	83	7	30333137
Pubmed	Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy.	GRK2 DYNC1H1 USP47	1.95e-05	22	83	3	17893145
Pubmed	A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.	TDRD7 SF3B1 KHDRBS3 TRNAU1AP KHDRBS2 SF3A3 RBM39	2.01e-05	347	83	7	16033648
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	PLOD3 MAP1B NUCB1 DBNL DCTN1 NUP160 RBM39 DYNC1H1 DDX3X PCNA	2.17e-05	803	83	10	36517590
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	WBP11 SF3B1 KHDRBS3 TRNAU1AP MAP3K20 SF3A3 VIRMA RBM39 DYNC1H1 DDX3X	2.26e-05	807	83	10	22681889
Pubmed	cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.	DVL1P1 DVL1	3.37e-05	4	83	2	8817329
Pubmed	Multiple modes of cytoplasmic dynein regulation.	DCTN1 DYNC1H1	3.37e-05	4	83	2	22373868
Pubmed	Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis.	ZSCAN5DP ZSCAN5C	3.37e-05	4	83	2	31155506
Pubmed	Human dishevelled genes constitute a DHR-containing multigene family.	DVL1P1 DVL1	3.37e-05	4	83	2	9192851
Pubmed	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites.	VIRMA METTL14	3.37e-05	4	83	2	24981863
Pubmed	Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.	GRK2 GRK3	3.37e-05	4	83	2	21784156
Pubmed	Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4.	DVL1P1 DVL1	3.37e-05	4	83	2	20639201
Pubmed	The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.	KHDRBS3 KHDRBS2	3.37e-05	4	83	2	15471878
Pubmed	WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork.	WRN PCNA	3.37e-05	4	83	2	14657243
Pubmed	Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.	GRK2 GRK3	3.37e-05	4	83	2	8917529
Pubmed	ZSCAN5B and primate-specific paralogs bind RNA polymerase III genes and extra-TFIIIC (ETC) sites to modulate mitotic progression.	ZSCAN5DP ZSCAN5C	3.37e-05	4	83	2	27732952
Pubmed	Phosphorylation of the type 1A angiotensin II receptor by G protein-coupled receptor kinases and protein kinase C.	GRK2 GRK3	3.37e-05	4	83	2	8662816
Pubmed	SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.	KHDRBS3 KHDRBS2	3.37e-05	4	83	2	22196734
Pubmed	Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels.	STIM2 KCNA2	3.37e-05	4	83	2	32186932
Pubmed	Binding of microtubule-associated protein 1B to LIS1 affects the interaction between dynein and LIS1.	MAP1B DYNC1H1	3.37e-05	4	83	2	15762842
Pubmed	Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.	GRK2 GRK3	3.37e-05	4	83	2	23734232
Pubmed	A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein.	DCTN1 DYNC1H1	3.37e-05	4	83	2	10189366
Pubmed	WRN participates in translesion synthesis pathway through interaction with NBS1.	WRN PCNA	3.37e-05	4	83	2	20600238
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	WBP11 SF3B1 SF3A3 VIRMA DDX3X	3.51e-05	154	83	5	16055720
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	PLOD3 SF3B1 IPO8 MAP1B UBR4 SF3A3 XPO4 LAMC1 COPS3 RBM39 JMY DYNC1H1 PCNA	3.54e-05	1440	83	13	30833792
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PPP2R3A GRK2 IPO8 DBNL DCTN1 RBM39 DYNC1H1 DDX3X PCNA USP47	3.61e-05	853	83	10	28718761
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	CHMP4A UBR4 LPP NUCB1 DBNL NUCB2 SF3A3 COPS3 NUP160 DYNC1H1 DDX3X PCNA USP47	3.94e-05	1455	83	13	22863883
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	HSD17B7 MAP1B UBR4 DCTN1 VIRMA NUP160 DYNC1H1 DDX3X PCNA	4.69e-05	704	83	9	29955894
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	WBP11 SF3B1 KHDRBS3 MAP1B KALRN KHDRBS2 RBM42 SF3A3 RBM39 DYNC1H1 DDX3X	5.24e-05	1082	83	11	38697112
Pubmed	Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine.	GRK2 GRK3	5.60e-05	5	83	2	10338466
Pubmed	WRN interacts physically and functionally with the recombination mediator protein RAD52.	WRN PCNA	5.60e-05	5	83	2	12750383
Pubmed	Role of dynein, dynactin, and CLIP-170 interactions in LIS1 kinetochore function.	DCTN1 DYNC1H1	5.60e-05	5	83	2	11889140
Pubmed	Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration.	MAP1B MAPK10	5.60e-05	5	83	2	20534829
Pubmed	Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis.	KHDRBS3 KHDRBS2	5.60e-05	5	83	2	10077576
Pubmed	Tudor-related proteins TDRD1/MTR-1, TDRD6 and TDRD7/TRAP: domain composition, intracellular localization, and function in male germ cells in mice.	TDRD7 DDX4	5.60e-05	5	83	2	17141210
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	SF3B1 IPO8 MAP1B PIK3C2B DCTN1 DYNC1H1 DDX3X PCNA	5.74e-05	558	83	8	27591049
Pubmed	NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.	ZSCAN5DP ZSCAN5C DDX4	6.18e-05	32	83	3	38060382
Pubmed	Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.	MAP1B DCTN1 DYNC1H1	7.43e-05	34	83	3	25915474
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	ADGB SF3B1 IPO8 SF3A3 DCTN1 NUP160 DYNC1H1 DDX3X PCNA	7.93e-05	754	83	9	35906200
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	CDR2 CCDC174 LPP MAP3K20 DYNC1H1 DDX3X	8.17e-05	298	83	6	30737378
Pubmed	Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.	MAPK10 DYNC1H1	8.39e-05	6	83	2	19525941
Pubmed	Dynamic expression of the RNA-binding protein Sam68 during mouse pre-implantation development.	KHDRBS3 KHDRBS2	8.39e-05	6	83	2	18321792
Pubmed	beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein.	GRK2 GRK3	8.39e-05	6	83	2	9826657
Pubmed	A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons.	DCTN1 DYNC1H1	8.39e-05	6	83	2	15208636
Pubmed	Function of the cytoplasmic tail of human calcitonin receptor-like receptor in complex with receptor activity-modifying protein 2.	GRK2 GRK3	8.39e-05	6	83	2	20074556
Pubmed	Cortical dynein is critical for proper spindle positioning in human cells.	DCTN1 DYNC1H1	8.39e-05	6	83	2	23027904
Pubmed	Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal.	VIRMA METTL14	8.39e-05	6	83	2	29547716
Pubmed	Functional association of U2 snRNP with the ATP-independent spliceosomal complex E.	SF3B1 SF3A3	8.39e-05	6	83	2	10882114
Pubmed	Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions.	GRK2 GRK3	8.39e-05	6	83	2	36451830
Interaction	TSPY8 interactions	TSPY3 TSPY2 TSPY8	6.02e-08	3	80	3	int:TSPY8
Interaction	MCM4 interactions	SF3B1 MCM8 MAP1B DBNL SF3A3 DCTN1 VIRMA RBM39 PCNA METTL14	3.62e-07	306	80	10	int:MCM4
Interaction	WBP4 interactions	WBP11 SF3B1 RBM42 SF3A3 RBM39 DDX3X	4.73e-06	109	80	6	int:WBP4
Interaction	IMPDH2 interactions	MAP1B UBR4 LPP MAPK10 VIRMA RBM39 JMY DYNC1H1 DDX3X PCNA	6.23e-06	420	80	10	int:IMPDH2
Interaction	BICD2 interactions	PPP2R3A GRK2 DBNL VPS41 COPS3 DCTN1 VIRMA NUP160 DYNC1H1 DDX3X	7.05e-06	426	80	10	int:BICD2
Interaction	SF3A3 interactions	PLOD3 SF3B1 SF3A3 COPS3 DCTN1 VIRMA RBM39 USP47 METTL14	8.06e-06	340	80	9	int:SF3A3
Interaction	CCDC88C interactions	CEP89 DVL1 DCTN1 VIRMA DYNC1H1	9.21e-06	71	80	5	int:CCDC88C
Interaction	DDX5 interactions	WBP11 SF3B1 DBNL KHDRBS2 RBM42 SF3A3 MAPK10 VIRMA RBM39 DDX3X METTL14	1.46e-05	568	80	11	int:DDX5
Interaction	SHANK3 interactions	TDRD7 WBP11 KHDRBS3 MAP1B KALRN DBNL DVL1 DCTN1 VIRMA DYNC1H1	2.62e-05	496	80	10	int:SHANK3
Interaction	SRSF9 interactions	KHDRBS3 RBM42 SF3A3 RBM39 DYNC1H1 DDX3X METTL14	3.05e-05	224	80	7	int:SRSF9
Interaction	ATXN2 interactions	TDRD7 KHDRBS3 TRNAU1AP KHDRBS2 RBM42 VIRMA RBM39 DDX3X	3.33e-05	312	80	8	int:ATXN2
Interaction	EED interactions	WBP11 PLOD3 SF3B1 MAP1B UBR4 VPS41 SF3A3 XPO4 LAMC1 COPS3 DCTN1 VIRMA NUP160 RBM39 DYNC1H1 DDX3X PCNA	4.25e-05	1445	80	17	int:EED
Interaction	HOOK1 interactions	PPP2R3A TBC1D7 VPS41 DCTN1 VIRMA DYNC1H1 USP47	4.72e-05	240	80	7	int:HOOK1
Interaction	DDX43 interactions	KHDRBS2 DDX53 DDX43	6.54e-05	20	80	3	int:DDX43
Interaction	LSM4 interactions	WBP11 SF3B1 RBM42 SF3A3 RBM39 METTL14	7.63e-05	178	80	6	int:LSM4
Interaction	VARS1 interactions	MAP1B UBR4 COPS3 VIRMA RBM39 PCNA METTL14	7.82e-05	260	80	7	int:VARS1
Interaction	SNRNP200 interactions	SF3B1 MAP1B UBR4 RBM42 SF3A3 COPS3 VIRMA RBM39 METTL14	8.59e-05	460	80	9	int:SNRNP200
Interaction	FBXW11 interactions	SF3B1 KHDRBS3 MAP1B TBC1D7 KHDRBS2 ACBD5 DYNC1H1 DDX3X USP47	1.06e-04	473	80	9	int:FBXW11
Interaction	SNRPA interactions	SF3B1 KHDRBS3 MAP1B RBM42 SF3A3 VIRMA RBM39 DYNC1H1 DDX3X	1.22e-04	482	80	9	int:SNRPA
Interaction	SYNCRIP interactions	SF3B1 IPO8 KHDRBS3 KHDRBS2 RBM42 SF3A3 VIRMA RBM39 DYNC1H1 DDX3X METTL14	1.26e-04	721	80	11	int:SYNCRIP
Interaction	TRMT10A interactions	SF3B1 DCTN1 VIRMA	1.30e-04	25	80	3	int:TRMT10A
Interaction	CTNNBL1 interactions	WBP11 TRNAU1AP WRN SF3A3 RBM39 USP47	1.33e-04	197	80	6	int:CTNNBL1
Interaction	MCM6 interactions	SF3B1 MCM8 SF3A3 DCTN1 VIRMA RBM39 METTL14	1.44e-04	287	80	7	int:MCM6
Interaction	RBM7 interactions	SF3B1 KHDRBS3 SF3A3 RBM39 PCNA	1.46e-04	126	80	5	int:RBM7
Interaction	CYLD interactions	PLOD3 SF3B1 IPO8 MAP1B PIK3C2B UBR4 DVL1 DCTN1 VIRMA DYNC1H1 DDX3X PCNA	1.53e-04	868	80	12	int:CYLD
Interaction	SRSF2 interactions	SF3B1 SF3A3 COPS3 DCTN1 RBM39 DYNC1H1 METTL14	1.54e-04	290	80	7	int:SRSF2
Interaction	DHX15 interactions	SF3B1 SF3A3 LAMC1 DDX43 VIRMA RBM39 DYNC1H1 DDX3X PCNA	1.66e-04	502	80	9	int:DHX15
Interaction	POLB interactions	HSD17B7 WRN PCNA USP47	1.93e-04	72	80	4	int:POLB
Interaction	EML4 interactions	MAP1B COPS3 DCTN1 VIRMA USP47	2.16e-04	137	80	5	int:EML4
Interaction	COPA interactions	SF3B1 MAP1B DBNL ACBD5 NUCB2 SF3A3 VIRMA METTL14	2.29e-04	412	80	8	int:COPA
Interaction	DDX53 interactions	DDX53 DDX43	2.31e-04	6	80	2	int:DDX53
Interaction	TSPY3 interactions	TSPY3 TSPY8	2.31e-04	6	80	2	int:TSPY3
Interaction	MCM7 interactions	SF3B1 MCM8 MAP1B DBNL DCTN1 VIRMA RBM39 PCNA	2.36e-04	414	80	8	int:MCM7
Interaction	PRPF8 interactions	WBP11 SF3B1 MAP1B UBR4 RBM42 SF3A3 VIRMA RBM39 DYNC1H1 DDX3X METTL14	2.39e-04	776	80	11	int:PRPF8
Interaction	U2AF2 interactions	SF3B1 KHDRBS3 MAP1B SF3A3 VIRMA RBM39 DYNC1H1 DDX3X PCNA METTL14	2.48e-04	651	80	10	int:U2AF2
Interaction	RANGAP1 interactions	IPO8 UBR4 LPP DBNL XPO4 DCTN1 VIRMA	2.50e-04	314	80	7	int:RANGAP1
Interaction	CALR3 interactions	PLOD3 NUCB1 NUCB2 LAMC1 CYP2U1	2.55e-04	142	80	5	int:CALR3
Interaction	RPS2 interactions	SF3B1 MAP1B UBR4 RBM42 SF3A3 VIRMA RBM39 DDX3X USP47 METTL14	2.67e-04	657	80	10	int:RPS2
Interaction	RPS6KA5 interactions	MAP1B RNF19A MAP3K20 VIRMA DYNC1H1	2.72e-04	144	80	5	int:RPS6KA5
Interaction	PRMT1 interactions	SF3B1 IPO8 KHDRBS3 MAP1B UBR4 KHDRBS2 SF3A3 VIRMA RBM39 DDX3X PCNA METTL14	2.87e-04	929	80	12	int:PRMT1
Interaction	SEPTIN14 interactions	C22orf42 DCTN1 METTL14	3.02e-04	33	80	3	int:SEPTIN14
Interaction	SAR1A interactions	STIM2 ACBD5 DCTN1 VIRMA NUP160 RBM39 DDX3X	3.08e-04	325	80	7	int:SAR1A
Interaction	CD2BP2 interactions	WBP11 SF3B1 RBM42 SF3A3 VIRMA RBM39	3.22e-04	232	80	6	int:CD2BP2
Cytoband	Yp11.2	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	4.39e-10	94	83	7	Yp11.2
Cytoband	Ensembl 112 genes in cytogenetic band chrYp11	TSPY4 TSPY3 TSPY10 TSPY2 TSPY9 TSPY8 TSPY1	1.16e-08	150	83	7	chrYp11
GeneFamily	DEAD-box helicases	DDX53 DDX43 DDX4 DDX3X	8.46e-06	42	56	4	499
GeneFamily	Signal transduction and activation of RNA metabolism family	KHDRBS3 KHDRBS2	2.82e-05	3	56	2	1275
Coexpression	WANG_LMO4_TARGETS_DN	CDR2 CHMP4A KALRN TBC1D7 UBR4 CYP2U1 VIRMA DYNC1H1 USP47	1.42e-06	361	79	9	M12674
Coexpression	CONRAD_GERMLINE_STEM_CELL	TSPY2 TSPY1 DDX4	7.37e-06	13	79	3	M15040
Coexpression	GSE17721_LPS_VS_CPG_1H_BMDC_DN	TBC1D8 SF3B1 KALRN RNF19A MAPK10 USP47	3.20e-05	200	79	6	M3987
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN	CDR2 WBP11 SF3B1 GRK2 RNF19A VIRMA NUP160 RBM39 JMY METTL14	3.72e-05	680	79	10	M41089
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Poorly_Differentiated_or_Epithelioid_Leiomyosarcoma-7\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	TSPY4 TSPY10 TSPY2 TSPY9 TSPY8	1.18e-06	99	83	5	4f0346fe85ba006d1ab28a61624568522ffe5cb4
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MOV10L1 LPP KHDRBS2 MAP3K20 MAPK10	1.66e-05	170	83	5	da4fb1e186e9bec6bba0b25f2a0e68f9e11c6017
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MOV10L1 LPP KHDRBS2 MAP3K20 MAPK10	1.66e-05	170	83	5	cb1ed6bd409ee1cf11be0d5e7cdcffe2ab220d38
ToppCell	RA-07._Pericyte\|World / Chamber and Cluster_Paper	MAP1B KALRN LPP ABCC9 MAPK10	2.31e-05	182	83	5	2075efeae633550fb2eb026d0dfd741c8252482e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SF3B1 MAP1B LPP LAMC1 USP47	2.49e-05	185	83	5	eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B KALRN MAP3K20 LAMC1 ABCC9	2.83e-05	190	83	5	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B KALRN MAP3K20 LAMC1 ABCC9	2.83e-05	190	83	5	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNA2 MAP1B KALRN MAP3K20 ABCC9	3.05e-05	193	83	5	0266a4fdf436d83ec1d9392abba8c6ec5166970a
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1B KALRN CDCA7 CCDC174 WRN	3.13e-05	194	83	5	b111d10c99d7ff7eb261cd7786cd9d9a549049b1
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KHDRBS3 MAP1B KALRN KHDRBS2 MAPK10	3.21e-05	195	83	5	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Control-Classical_Monocyte-cMono_2\|Classical_Monocyte / Disease condition and Cell class	SF3B1 GRK2 GRK3 RBM39 DDX3X	3.37e-05	197	83	5	eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	SF3B1 RNF19A RBM39 DYNC1H1 DDX3X	3.62e-05	200	83	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MAP1B LPP MAP3K20 LAMC1 ABCC9	3.62e-05	200	83	5	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
Disease	hypothyroidism (biomarker_via_orthology)	PLOD3 GRK3 MAP1B PCNA	4.48e-05	80	72	4	DOID:1459 (biomarker_via_orthology)
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	5.84e-05	5	72	2	DOID:11198 (is_implicated_in)
Disease	neurodegenerative disease (implicated_via_orthology)	DVL1P1 CEP89 DVL1 DYNC1H1	4.44e-04	145	72	4	DOID:1289 (implicated_via_orthology)
Disease	anti-Mullerian hormone measurement	MCM8 CDCA7	1.08e-03	20	72	2	EFO_0004769
Disease	seminoma (is_marker_for)	TSPY1 PCNA	1.31e-03	22	72	2	DOID:4440 (is_marker_for)
Disease	coronary artery disease	PPP2R3A GRK3 MAP1B TBC1D7 KHDRBS2 SF3A3 LAMC1 NUP160 CFB	2.43e-03	1194	72	9	EFO_0001645

Protein segments in the cluster

Peptide	Gene	Start	Entry
QVSMLAVDEMYDDLA	BEST2	316	Q8NFU1
MADLEAVLADVSYLM	GRK3	1	P35626
AYQDMDIDKVDELMT	CHMP4A	116	Q9BY43
AMERLKEQYAEMEKD	BLOC1S5	166	Q8TDH9
YLDVDMMDICKENGA	COPS3	161	Q9UNS2
KYLVLDEADRMLDMG	DDX4	441	Q9NQI0
ALEAKERYMEEMADT	DCTN1	286	Q14203
ERYMEEMADTADAIE	DCTN1	291	Q14203
DEVLDMYKEMQDSLD	ADGB	1596	Q8N7X0
LVKDMVEYKDRCMAD	AFM	66	P43652
GDMTKEEAMIAYVEE	ACBD5	106	Q5T8D3
MYSREAKAQMEDEDE	ABCC9	941	O60706
MDPLELDDYHEKMVA	C7orf31	291	Q8N865
EDLMTPEMAKERYED	C22orf42	211	Q6IC83
EAMDLREDKDFLEDM	CDR1	71	P51861
MADLEAVLADVSYLM	GRK2	1	P25098
MADDIDIEAMLEAPY	RBM39	1	Q14498
EERLKEMEAEMALFE	RBM42	31	Q9BTD8
KDMENLEDVFYQMID	CFB	456	P00751
EMEKYADREDMIIMF	PLOD3	96	O60568
CKYLVLDEADRMLDM	DDX3X	341	O00571
EEIRFYELGEEAMEM	KCNA2	111	P16389
EAMEMFREDEGYIKE	KCNA2	121	P16389
PEKMEAEDYVMAVVD	MAP1B	1036	P46821
EEIYAEMELKEYNMS	MOV10L1	541	Q9BXT6
YESMEAMLEKEEMAA	JMY	576	Q8N9B5
LEEFQDVYLVMELMD	MAPK10	136	P53779
DAEDIVEIMKYSMLG	MCM8	736	Q9UJA3
KMEEYKDELEMQQDE	METTL14	76	Q9HCE5
VSDYEMKLMDLDVEQ	PCNA	111	P12004
LDYLMNHDELMEEKV	KALRN	2766	O60229
KHLMEMAEEERLEYQ	KIAA2012	1116	Q0VF49
DELEHLTKKMLYDME	LPP	391	Q93052
KVYDPKNEEDDMVEM	NUCB2	276	P80303
VYDPKNEEDDMREME	NUCB1	276	Q02818
FMDIEEQKADIYEMG	PPP2R3A	736	Q06190
RKELAMAEALQMEYD	PIK3C2B	21	O00750
DFIDMYLLHMEEERK	CYP2U1	316	Q7Z449
MLAENLVEEFEMKED	CDR2	1	Q01850
LAYEDMMKEKDELNA	CEP89	371	Q96ST8
YIMTQKMDLDEDTAE	HSD17B7	296	P56937
MEMDGDEIAITYIKD	MAP3K20	461	Q9NYL2
MQMLEDEDDLAYAET	DYNC1H1	4346	Q14204
MEEEKYLPELMAEKD	KHDRBS2	1	Q5VWX1
MEEKYLPELMAEKDS	KHDRBS3	1	O75525
AIMDYNRDIEEIMKD	LAMC1	1571	P11047
TYLVIDEADKMLDME	DDX53	371	Q86TM3
MTKGDFIDEEVEDMY	CCDC174	96	Q6PII3
MAETKIIYHMDEEET	DVL1	1	O14640
MAETKIIYHMDEEET	DVL1P1	1	P54792
MAAELRMILYEDDSV	C5orf34	1	Q96MH7
IKEEFTDEEMQYDMA	RNASE11	26	Q8TAA1
TYLVLDEADKMLDMG	DDX43	391	Q9NXZ2
EEMVEELNSGKVMYA	DBNL	51	Q9UJU6
DEYEEVEDKTVMAMG	IPO8	596	O15397
EFMEQSEELYDALMD	TRNAU1AP	256	Q9NX07
EFLDTKDLMMFLEAE	PLCL2	356	Q9UPR0
YVIESDEDLEMEMLK	WRN	436	Q14191
DYSAAQELMEDEMKE	TDRD7	486	Q8NHU6
DEVFLAIAKAMEEMV	TBC1D7	131	Q9P0N9
IREMDYETEVEMEKG	NUP160	676	Q12769
MEEEEEEDKYMLVRK	CDCA7	196	Q9BWT1
DEDEDMLSYMVSLEV	TSPY9	181	A0A494C1R9
ALITDEDEDMLSYMV	TSPY10	171	P0CW01
EDEDMLSYMVSLEVE	TSPY10	176	P0CW01
ALITDEDEDMLSYMV	TSPY2	171	A6NKD2
EDEDMLSYMVSLEVE	TSPY2	176	A6NKD2
EMAEDIEDLDHYEMK	UBE2Q2	146	Q8WVN8
DEDEDMLSYMVSLEV	TSPY4	181	P0CV99
AALEEVLDKDDMVYM	XPO4	386	Q9C0E2
LGKEYLMQESDVEMA	ZSCAN5DP	131	P0CG00
ALITDEDEDMLSYMV	TSPY1	171	Q01534
ILSDDVLMEKYEEFM	RNF19A	191	Q9NV58
LERKMMDEINYAKEE	STIM2	286	Q9P246
DLKDEAEQYRKMVME	SF3B1	856	O75533
DLEELYDLFKREHMM	TBC1D8	816	O95759
EAVEMAYKMMDLEEV	USP47	636	Q96K76
YFQEDKKEMMEELVE	PHEX	426	P78562
IVLLMDFDSEKAVDM	VPS41	556	P49754
MAALMAQVEYGDLEK	PLEKHH1	1136	Q9ULM0
ALITDEDEDMLSYMV	TSPY3	171	P0CV98
EDEDMLSYMVSLEVE	TSPY3	176	P0CV98
ALITDEDEDMLSYMV	TSPY8	171	P0CW00
EDEDMLSYMVSLEVE	TSPY8	176	P0CW00
VLMEKMGDHLALEDY	SERPINA10	301	Q9UK55
YHEEKERLMDVMAKE	SF3A3	11	Q12874
KDDVYEAFMKEMEGL	WBP11	626	Q9Y2W2
EEDEEEVYKMAGVMA	UBR4	4466	Q5T4S7
YENEVEASMDMDLLE	VIRMA	601	Q69YN4
KEYLMQESDVEMAEA	ZSCAN5C	136	A6NGD5