Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainN-CoR_GPS2_interact

NCOR1 NCOR2

7.95e-0521672IPR031557
DomainGPS2_interact

NCOR1 NCOR2

7.95e-0521672PF15784
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA6B PLXNA3 CRYBG2 ADGRB2 NDUFA1 MBD6 MAST2 ZZEF1 POM121C AHDC1 SYNE4 MST1R PRR12 NCOR1 NCOR2 LMAN2L TRIM28 XXYLT1 TNKS1BP1 LTK MMP17 TRAPPC9 AHNAK2

7.58e-0911051732335748872
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

DDX17 CENPC DSP MBNL1 NOL6 U2AF2 POGZ SREK1 MCCC1 RFX5 PPP1R10 NCOR1 NCOR2 MED19 TRIM28 CSNK2B HSD17B10 ATP5F1B SON

3.29e-079541731936373674
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

CAD DDX17 MBOAT7 DSP PATZ1 PUM2 U2AF2 SREK1 CHN2 POM121C NCOR2 ZNF668 ESYT2 MGMT TRIM28

1.12e-066551731535819319
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CNTN4 GRIPAP1 ARHGAP39 POM121C PRX LRIG2 PRR12 AHRR POM121 DSTYK ZNF518B GRIN3A TRAPPC9

1.28e-064931731315368895
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FAM120B CAD DDX17 DSP RBM42 U2AF2 POGZ SREK1 ARHGAP39 DBT USP9Y AHDC1 ZCCHC4 PPP1R10 TRIM28 TNKS1BP1 TNXB UNC13A SON

2.13e-0610821731938697112
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

CAD DDX17 MBOAT7 SCAF8 MBNL1 NOL6 PUM2 U2AF2 SREK1 MCCC1 DBT ABHD14B NCOR1 ESYT2 MED19 TRIM28 CSNK2B HSD17B10 FH ATP5F1B SON

2.77e-0613181732130463901
Pubmed

The DNA sequence and biological annotation of human chromosome 1.

NPL CRYBG2 DDX59 TMEM69 ADGRB2 RIIAD1 POGZ TMEM222 MAST2 RFX5 ITPKB GARIN4 SMPDL3B HMCN1 MTF1 CYB561D1 SCNN1D USH2A

4.34e-0610311731816710414
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

DDX17 DSP PATZ1 RBM42 U2AF2 POGZ MCCC1 POM121C RFX5 THAP1 AHDC1 PRR12 PPP1R10 NCOR1 NCOR2 ZNF668 ESYT2 TRIM28 ATP5F1B SON

7.61e-0612941732030804502
Pubmed

BioID-based proteomic analysis of the Bid interactome identifies novel proteins involved in cell-cycle-dependent apoptotic priming.

DSP MCCC1 FH SON AHNAK2

8.17e-0655173533067418
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

CAD DDX17 DSP NOL6 RBM42 U2AF2 SREK1 ZCCHC4 ZNF668 TRIM28 HSD17B10 TRAPPC9 ATP5F1B SON

8.38e-066781731430209976
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

CAD DDX17 COL13A1 DSP U2AF2 MCCC1 ZZEF1 POM121C LGALS3 CORO1A TRIM28 HSD17B10 FH ATP5F1B AHNAK2

1.37e-058071731530575818
Pubmed

Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells.

DDX17 NCOR1 NCOR2

1.41e-0510173312738788
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FNDC3B FAM120B CAD DDX17 ILK COMT CENPC MBOAT7 DSP NOL6 U2AF2 POGZ MCCC1 ABHD14B NCOR2 TRIM28 CSNK2B ATP5F1B SON AHNAK2

1.45e-0513531732029467282
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

FNDC3B CAD MBOAT7 SCAF8 NOL6 RBM42 PUM2 SREK1 ARHGAP39 AHDC1 LGALS3 PRR12 PPP1R10 ESYT2 MED19 LMAN2L SLC25A40 CXXC4 HSD17B10 ATP5F1B SON

1.90e-0514971732131527615
Pubmed

Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival.

HPSE LGALS3

2.46e-052173221153652
Pubmed

CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas.

NCOR1 NCOR2

2.46e-052173227733359
Pubmed

Corepressors (NCoR and SMRT) as well as coactivators are recruited to positively regulated 1α,25-dihydroxyvitamin D3-responsive genes.

NCOR1 NCOR2

2.46e-052173222944139
Pubmed

KAP1 Regulates Regulatory T Cell Function and Proliferation in Both Foxp3-Dependent and -Independent Manners.

TRIM28 FOXP3

2.46e-052173229669285
Pubmed

Aberrant corepressor interactions implicated in PML-RAR(alpha) and PLZF-RAR(alpha) leukemogenesis reflect an altered recruitment and release of specific NCoR and SMRT splice variants.

NCOR1 NCOR2

2.46e-052173221131350
Pubmed

Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways.

NCOR1 NCOR2

2.46e-052173219299558
Pubmed

Unique forms of human and mouse nuclear receptor corepressor SMRT.

NCOR1 NCOR2

2.46e-052173210077563
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

2.46e-052173234910522
Pubmed

RNF112-mediated FOXM1 ubiquitination suppresses the proliferation and invasion of gastric cancer.

FOXM1 RNF112

2.46e-052173237288663
Pubmed

Nuclear Receptor Corepressors NCOR1 and SMRT Regulate Metabolism via Intestinal Regulation of Carbohydrate Transport.

NCOR1 NCOR2

2.46e-052173239106294
Pubmed

Evolution of NCoR-1 and NCoR-2 corepressor alternative mRNA splicing in placental mammals.

NCOR1 NCOR2

2.46e-052173231208445
Pubmed

NCoR/SMRT co-repressors cooperate with c-MYC to create an epigenetic barrier to somatic cell reprogramming.

NCOR1 NCOR2

2.46e-052173229531310
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

2.46e-052173211687802
Pubmed

Mammalian hemicentin 1 is assembled into tracks in the extracellular matrix of multiple tissues.

HMCN2 HMCN1

2.46e-052173232035013
Pubmed

A timer for analyzing temporally dynamic changes in transcription during differentiation in vivo.

NR4A3 FOXP3

2.46e-052173229941474
Pubmed

The C-terminal domain of PLD2 participates in degradation of protein kinase CKII β subunit in human colorectal carcinoma cells.

CSNK2B PLD2

2.46e-052173221944249
Pubmed

Regulation of corepressor alternative mRNA splicing by hormonal and metabolic signaling.

NCOR1 NCOR2

2.46e-052173226166430
Pubmed

Tight correlation between FoxM1 and FoxP3+ Tregs in gastric cancer and their clinical significance.

FOXM1 FOXP3

2.46e-052173229804142
Pubmed

TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.

DDX17 DSP MCCC1 DBT TRIM28 DSTYK SCNN1D QDPR ATP5F1B

3.25e-05317173930997501
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

SCAF8 MBNL1 MCCC1 POM121C PRR12 NCOR1 NCOR2

3.50e-05180173735198878
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FOXM1 DSP SCAF8 PUM2 POGZ ARHGAP39 FBXO38 NCOR1 NCOR2 ESYT2 MGMT TRIM28 TNKS1BP1 SON

3.60e-057741731415302935
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADGRB2 CUBN UNC5A HMCN1 ADAMTS17

3.74e-0575173520637190
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

DSP SCAF8 RFX5 PRR12 PPP1R10 NCOR1 NCOR2

4.02e-05184173732908313
Pubmed

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

GRIPAP1 PPP1R3F FOXP3

4.23e-0514173311138001
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ATP7B PATZ1 KIAA1549 U2AF2 POGZ SREK1 DBT MAST2 ZZEF1 POM121C NCOR2 ZNF469 HMCN2 TRIM28 CSNK2B LTK SON

4.56e-0511161731731753913
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

PLXNA3 CRYBG2 GGT1 PPP1R10 CORO1A

6.46e-0584173515203218
Pubmed

A novel nuclear receptor corepressor complex, N-CoR, contains components of the mammalian SWI/SNF complex and the corepressor KAP-1.

NCOR1 NCOR2 TRIM28

6.46e-0516173311013263
Pubmed

Interaction network of human early embryonic transcription factors.

SATB2 POGZ DBT MBD6 POM121C AHDC1 PRR12 NCOR1 NCOR2

7.12e-05351173938297188
Pubmed

Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.

HMCN2 HMCN1

7.36e-053173212388743
Pubmed

Functional interactions with Pit-1 reorganize co-repressor complexes in the living cell nucleus.

NCOR1 NCOR2

7.36e-053173216030140
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

7.36e-053173230801007
Pubmed

Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65.

MBNL1 U2AF2

7.36e-053173226218986
Pubmed

Involvement of SMRT corepressor in transcriptional repression by the vitamin D receptor.

NCOR1 NCOR2

7.36e-053173219098224
Pubmed

POM121 inhibits the macrophage inflammatory response by impacting NF-κB P65 nuclear accumulation.

POM121C POM121

7.36e-053173230802453
Pubmed

The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor.

NCOR1 NCOR2

7.36e-053173216373395
Pubmed

Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action.

NCOR1 NCOR2

7.36e-053173231404087
Pubmed

SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells.

FOXM1 SATB2

7.36e-053173233124191
Pubmed

Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine.

POM121C POM121

7.36e-053173235507432
Pubmed

Nuclear receptor co-repressors are required for the histone-deacetylase activity of HDAC3 in vivo.

NCOR1 NCOR2

7.36e-053173223292142
Pubmed

Deacetylase-independent function of HDAC3 in transcription and metabolism requires nuclear receptor corepressor.

NCOR1 NCOR2

7.36e-053173224268577
Pubmed

Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their downregulation in colorectal cancer.

COMT MGMT

7.36e-053173230379684
Pubmed

Oligomerization of ETO is obligatory for corepressor interaction.

NCOR1 NCOR2

7.36e-053173211113190
Pubmed

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis.

IL10RB FOXP3

7.36e-053173219783988
Pubmed

Cutting Edge: a novel, human-specific interacting protein couples FOXP3 to a chromatin-remodeling complex that contains KAP1/TRIM28.

TRIM28 FOXP3

7.36e-053173223543754
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

PRX AHNAK2

7.36e-053173221940993
Pubmed

EBV nuclear antigen EBNALP dismisses transcription repressors NCoR and RBPJ from enhancers and EBNA2 increases NCoR-deficient RBPJ DNA binding.

NCOR1 NCOR2

7.36e-053173221518914
Pubmed

Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT.

NCOR1 NCOR2

7.36e-053173215802375
Pubmed

SMRT and NCoR1 fine-tune inflammatory versus tolerogenic balance in dendritic cells by differentially regulating STAT3 signaling.

NCOR1 NCOR2

7.36e-053173236238311
Pubmed

A secreted protein promotes cleavage furrow maturation during cytokinesis.

HMCN2 HMCN1

7.36e-053173221215633
Pubmed

Structural basis for nuclear receptor corepressor recruitment by antagonist-liganded androgen receptor.

NCOR1 NCOR2

7.36e-053173218852122
Pubmed

Cubilin, a binding partner for galectin-3 in the murine utero-placental complex.

CUBN LGALS3

7.36e-053173211856751
Pubmed

The regulation of integrin-linked kinase in human platelets: evidence for involvement in the regulation of integrin alpha 2 beta 1.

ILK ITGA2

7.36e-053173215304053
Pubmed

Regulatory T cells suppress CD4+ effector T cell activation by controlling protein synthesis.

IL10RB FOXP3

7.36e-053173236598533
Pubmed

Regulated clearance of histone deacetylase 3 protects independent formation of nuclear receptor corepressor complexes.

NCOR1 NCOR2

7.36e-053173222337871
Pubmed

Equilibrium interactions of corepressors and coactivators with agonist and antagonist complexes of glucocorticoid receptors.

NCOR1 NCOR2

7.36e-053173215016838
Pubmed

Expression of FOXP3, CD14, and ARG1 in Neuroblastoma Tumor Tissue from High-Risk Patients Predicts Event-Free and Overall Survival.

CD14 FOXP3

7.36e-053173226161395
Pubmed

Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis.

NCOR1 NCOR2

7.36e-053173234390859
Pubmed

Disease-causing point-mutations in metal-binding domains of Wilson disease protein decrease stability and increase structural dynamics.

ATP7B MBD6

7.36e-053173227744583
Pubmed

Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.

CSNK2B FOXP3

7.36e-053173225599562
Pubmed

Hemicentins assemble on diverse epithelia in the mouse.

HMCN2 HMCN1

7.36e-053173217015624
Pubmed

RU486-induced glucocorticoid receptor agonism is controlled by the receptor N terminus and by corepressor binding.

NCOR1 NCOR2

7.36e-053173212011091
Pubmed

Galectin-Binding O-Glycosylations as Regulators of Malignancy.

ST6GAL1 LGALS3

7.36e-053173226224120
Pubmed

miR-106b-5p induces immune imbalance of Treg/Th17 in immune thrombocytopenic purpura through NR4A3/Foxp3 pathway.

NR4A3 FOXP3

7.36e-053173232323598
Pubmed

The nuclear receptor corepressor N-CoR regulates differentiation: N-CoR directly interacts with MyoD.

NCOR1 NCOR2

7.36e-053173210406466
Pubmed

Nuclear corepressors NCOR1/NCOR2 regulate B cell development, maintain genomic integrity and prevent transformation.

NCOR1 NCOR2

7.36e-053173236316474
Pubmed

The functional relationship between co-repressor N-CoR and SMRT in mediating transcriptional repression by thyroid hormone receptor alpha.

NCOR1 NCOR2

7.36e-053173218052923
Pubmed

The transcription factor B-Myb is maintained in an inhibited state in target cells through its interaction with the nuclear corepressors N-CoR and SMRT.

NCOR1 NCOR2

7.36e-053173211997503
Pubmed

Proteome-wide Identification of HtrA2/Omi Substrates.

CAD TRIM28 HSD17B10

7.81e-0517173317266347
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

FOXM1 SATB2 MCCC1 AHDC1 PPP1R10 NCOR1 NCOR2 TRIM28 TNKS1BP1 AHNAK2

8.31e-054441731034795231
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

FNDC3B SCAF8 MBNL1 PUM2 POM121C AHDC1 PRR12 NCOR1 NCOR2 POM121

1.05e-044571731032344865
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ILK DSP PATZ1 MCCC1 MAST2 E2F8 ITPKB ESYT2 DSTYK TESK2 TNKS1BP1 CSPP1 TRAPPC9 AHNAK2

1.12e-048611731436931259
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

SEMA6B PLXNA3 CNTN4 UNC5A

1.33e-0452173426633812
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

AEN DDX17 CENPC DSP NOL6 U2AF2 SREK1 MCCC1 PPP1R10 NCOR2 TRIM28 CSNK2B HSD17B10 ATP5F1B SON

1.36e-049891731536424410
Pubmed

Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.

STRC STRCP1

1.47e-044173218849963
Pubmed

Silencing mediator for retinoid and thyroid hormone receptor and nuclear receptor corepressor attenuate transcriptional activation by the beta-catenin-TCF4 complex.

NCOR1 NCOR2

1.47e-044173218632669
Pubmed

A selective peroxisome proliferator-activated receptor-gamma modulator, telmisartan, binds to the receptor in a different fashion from thiazolidinediones.

NCOR1 NCOR2

1.47e-044173219147680
Pubmed

GARP: a key receptor controlling FOXP3 in human regulatory T cells.

LGALS3 FOXP3

1.47e-044173219453521
Pubmed

NCoR1 and SMRT play unique roles in thyroid hormone action in vivo.

NCOR1 NCOR2

1.47e-044173225421714
Pubmed

Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this interaction is modulated by MEK.

NCOR1 NCOR2

1.47e-044173215878880
Pubmed

FBI-1 functions as a novel AR co-repressor in prostate cancer cells.

NCOR1 NCOR2

1.47e-044173220812024
Pubmed

The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3.

NCOR1 NCOR2

1.47e-044173211509652
Pubmed

Two distinct human POM121 genes: requirement for the formation of nuclear pore complexes.

POM121C POM121

1.47e-044173217900573
Pubmed

[Decreased expression levels of LAG-3 and CD49b on CD14+ cells in peripheral blood of patients with recurrent spontaneous abortion].

ITGA2 CD14

1.47e-044173226927558
Pubmed

The retinoid X receptor binding to the thyroid hormone receptor: relationship with cofactor binding and transcriptional activity.

NCOR1 NCOR2

1.47e-044173219211732
Pubmed

CD49b defines functionally mature Treg cells that survey skin and vascular tissues.

ITGA2 FOXP3

1.47e-044173230355617
Pubmed

GART, SON, IFNAR, and CRF2-4 genes cluster on human chromosome 21 and mouse chromosome 16.

IL10RB SON

1.47e-04417328318737
InteractionBID interactions

DSP PLEKHA4 MCCC1 RBM48 CSNK2B HSD17B10 FH SON AHNAK2

4.97e-061491709int:BID
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CA9 PLXNA3 FAM120B ILK POM121C LMAN1L AHRR POM121 TNKS1BP1 AHNAK2

6.21e-091991731085bb28369e0568b7b3bda095722102fc793f60ef
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL|Int-URO / Disease, condition lineage and cell class

DDX59 UBASH3A ABHD14B LRIG2 ARL10 ZFYVE9 CARF CYB561D1

1.11e-061981738717735d755745439f97ba1b71785c73945dfa9c5
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

CRYBG2 UBASH3A ARL10 LMAN2L SCNN1D PPP1R3F IBA57-DT

4.15e-061671737c0c944eae0514dc8e00d0c2892a0792e157695ec
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B SATB2 CENPC MBOAT7 MBNL1 CORO1A FAM186A

4.85e-061711737dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FNDC3B SATB2 CENPC MBOAT7 MBNL1 CORO1A FAM186A

4.85e-0617117372b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

CRYBG2 ARL10 LMAN2L SCNN1D PPP1R3F PLD2 IBA57-DT

5.24e-06173173742c911ed16fabdabef063830e8407192d8bde950
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KATNB1 NACAD SLC39A13 ZNF668 HMCN1 C10orf105 TNXB

5.44e-0617417371d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TDRD9 MBOAT7 CHN2 CORO1A PTPRE CD14 CYB561D1

6.55e-06179173761dbfc1b9b0344c06a68142c181cd62993556a67
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 SATB2 KIAA1549 CUBN GGT1 UNC5CL PCK1

7.57e-0618317376878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellControl|World / Disease state, Lineage and Cell class

NPL SEMA6B FNDC3B NCOR2 PTPRE CD14 DGKI

9.34e-061891737fb8dddd3b901081c6bb9ed6f32dafc5cce5f30be
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRGPRF HMCN1 PLAGL1 MMP17 TNXB AHNAK2 ARMH4

9.67e-061901737947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MRGPRF HMCN1 PLAGL1 MMP17 TNXB AHNAK2 ARMH4

1.00e-051911737db4943dd19207663fb9e27f8940fa4b06a933625
ToppCellMonocytes-Phagocytic_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

NPL FNDC3B COMT HPSE LGALS3 GLMP CD14

1.11e-05194173740dbfdf1d7e6b73d120d8f802f08e573fe9a739e
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_2|E18.5-samps / Age Group, Lineage, Cell class and subclass

CNTN4 ADGRB2 CHN2 SYNE4 LTK ARMH4

1.24e-051311736f2eee150f5cff852e8f52f09b35e26f17d80833b
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CAD PLEKHA4 ETV4 SEC31B NCOR2 TNXB SLC26A6

1.35e-05200173724e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCellfacs-Lung-Endomucin-24m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA9 HPSE LGALS3 CORO1A CD14 SLC26A6

3.00e-0515317369c3220604b7fa4d91577b6c46960960f49644ca1
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA9 HPSE LGALS3 CORO1A CD14 SLC26A6

3.00e-051531736ba624782693b0daa642e50881dbf5f0663fea82d
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PKD1L2 HPSE LGALS3 CORO1A AHRR CD14

3.59e-051581736b35bab2b93d0af821bfae18a358eb7dddaf3860f
ToppCellfacs-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PKD1L2 HPSE LGALS3 CORO1A AHRR CD14

3.59e-0515817367bd4a64a610eb1cbcd3d07ea5258a55107cf6c00
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

CNTN4 SATB2 PLEKHA4 NR4A3 EGR4 LTK

3.72e-05159173618e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellBronchial_Biopsy-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

SLC16A13 ITPKB WDR93 FBXO38 ZNF469 MMP17

4.13e-051621736985adca17b0c99563feef7910f3da5df31e636b6
ToppCellfacs-Heart-LV-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPL PTCRA LGALS3 CORO1A SMPDL3B CD14

4.13e-0516217365dfdb4e227e5d7d72dbe8fe032791fddb0be064d
ToppCellfacs-Heart-LV-24m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPL PTCRA LGALS3 CORO1A SMPDL3B CD14

4.13e-0516217367f26135b884144473bbccaf3881c8cf2ba4fa05a
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7B KIAA1549 CUBN E2F8 PTPRE ARMH4

4.42e-0516417360853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MRGPRF GARIN4 ZNF469 TRIM28 STRC ARMH4

4.73e-051661736dc443a3327dc8f9a0d808c3c6e06b0834d45f5c2
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

SEMA6B ENOX1 MRGPRF ZNF469 SLC16A2 FOXP3

5.05e-051681736aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM120B CAD CENPC ARHGAP39 ZCCHC4 TRAPPC9

5.05e-051681736b9db0b1e4fe54a1fe79530d15d206155a1bfac39
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_F|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CAD KATNB1 ACOX2 MGMT STOML1 MMP17

5.40e-05170173671718dcebd48105994c313bb55babc70301170a0
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R3G CHN2 CORO1A AHRR PTPRE C10orf105

5.58e-0517117361018d7bd378ce20bee56a77d5851b3538c55098c
ToppCelldroplet-Heart-4Chambers-21m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT7 HPSE PPP1R10 POM121 SMPDL3B HMCN1

5.58e-051711736e852d0e8589eecf4a2e5fea039b52a67c5d58dbd
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R3G CHN2 CORO1A AHRR PTPRE C10orf105

5.58e-051711736173bb5318fdbaef6e695b6f9e3e0ff4a5432a1a4
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PPP1R3G CHN2 CORO1A AHRR PTPRE C10orf105

5.58e-0517117366bda333bb751d7835a04f21ac959eea79f2516aa
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ENOX1 ST6GAL1 PRR12 LMAN2L SLC26A6 FOXP3

6.75e-05177173636b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA9 RIIAD1 WDR93 MST1R LRRC46 C10orf105

6.75e-051771736e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CNTN4 FNDC3B MRGPRF PLEKHA4 NR4A3 GGT1

6.96e-051781736cb9a446c145b1435cfe12a1d4568aed0924a6a20
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CA9 RNF112 MRGPRF NR4A3 PLAGL1 AHNAK2

6.96e-051781736a107dd98a07086ed0429116095ecda60c9dbef1e
ToppCell3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIIAD1 ACOX2 ARL10 EGR4 QDPR USH2A

7.18e-051791736878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 KIAA1549 CUBN SLCO1A2 PCK1 SLC26A6

7.18e-051791736d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7B KIAA1549 E2F8 PTPRE ADAMTS17 ARMH4

7.64e-051811736ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7B KIAA1549 E2F8 PTPRE ADAMTS17 ARMH4

7.64e-0518117364e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP7B KIAA1549 E2F8 PTPRE ADAMTS17 ARMH4

7.64e-0518117363a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellT_cells-Resident_memory_CD8+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CRYBG2 ITGA2 UBASH3A CHN2 NACAD LGALS3

7.87e-051821736111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF112 FMNL3 UNC5A PTPRE MMP17 TNXB

7.87e-05182173641b070085edba7a58b81c20aa4942d06f745acf8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF112 FMNL3 UNC5A PTPRE MMP17 TNXB

7.87e-0518217365e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF112 FMNL3 UNC5A PTPRE MMP17 TNXB

7.87e-051821736b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCellfacs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DSP CUBN DBT THAP1 SMPDL3B ARMH4

8.11e-0518317366e5b39c0170d62eb7fdd411dcfff51ed176573d0
ToppCellT_cells-Resident_memory_CD8+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CRYBG2 ITGA2 UBASH3A CHN2 LGALS3 ADAMTS17

8.36e-051841736e04cabff33a8e36967622ec3e5b37b89afa7e148
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

CNTN4 SATB2 KIAA1549 CUBN GGT1 UNC5CL

8.36e-05184173651ed1ebfdef45149541917c66cbacad87072e51f
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SATB2 RNF112 CHN2 GARIN4 PLAGL1 TRPM1

8.36e-051841736e123ad8ee46a032825a0bd4b3586ddcb3eda03d4
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SATB2 ADGRB2 NR4A3 UNC5A EGR4 LTK

8.36e-05184173625ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLEKHA4 KIAA1549 ST6GAL1 ARHGAP39 PRX ARMH4

8.61e-05185173611c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

CNTN4 PATZ1 RFX5 PRX AHRR

9.01e-051161735f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MRGPRF ADGRB2 ETV4 NACAD SLC16A2 TNXB

9.68e-051891736473b01c9162b12b90a617c600238436177a0d18d
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A3 PPP1R3G CHN2 CORO1A PTPRE C10orf105

1.03e-041911736f814dc20034bafa1c0e8dfe98e58370cf3f73bee
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A3 PPP1R3G CHN2 CORO1A PTPRE C10orf105

1.03e-0419117361155c28407ff97d950d70d53256a9fb6307a2bac
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6B RASIP1 HMCN1 SLC16A2 NYNRIN C10orf105

1.03e-0419117369fc674a58f20b47255e4457d5195c8cff17b0414
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA6B RASIP1 HMCN1 SLC16A2 NYNRIN C10orf105

1.03e-041911736c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCellControl-Myeloid-MoAM3,_VCAN|Control / Condition, Lineage and Cell class

HPSE ACOX2 LGALS3 GLMP CORO1A CD14

1.03e-04191173676c2fbc62855a65600cd6b8dd1e2d2c3d7415921
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-conventional_dendritic_cell-DC1_(conventional_dendritic_cell)-DC1_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A3 PPP1R3G CHN2 CORO1A PTPRE C10orf105

1.03e-0419117368947010e47218095c5032f24c41e245e7977a33d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RB FMNL3 RASIP1 ESYT2 HMCN1 SLC16A2

1.06e-0419217369ae05db5bfb8b9d3935c0328e6f2d489d2b1ebfd
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RB FMNL3 RASIP1 ESYT2 HMCN1 SLC16A2

1.06e-041921736a116db7dec495e5a0ba9c7537057cd1e567d7885
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL10RB FMNL3 RASIP1 ESYT2 HMCN1 SLC16A2

1.06e-04192173666defad13bd8e79319741e43ddb056841710b1d7
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FNDC3B MBNL1 ARL10 DGKI TRAPPC9 ARMH4

1.09e-041931736779276e775cb2492e8dd36436295a536084a6415
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SATB2 DSP ST6GAL1 CUBN LGALS3 PCK1

1.09e-04193173632eb026d4317c1499d51294d396dfd5f293f9deb
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SATB2 DSP ST6GAL1 CUBN LGALS3 PCK1

1.09e-041931736930df79b0600f43617052313294be33bcf5631f0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL13A1 ST6GAL1 FMNL3 RASIP1 PTPRE TNXB

1.12e-041941736b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCell(0)_NK_cells-(0)_NK_CD160pos|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

DDX17 MBNL1 CHN2 SMPDL3B ADAMTS17 SON

1.15e-0419517366cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCellMesenchymal_cells-Fibro/Chondro_p.|Mesenchymal_cells / Lineage and Cell class

CA9 KIAA1549 LGALS3 PTPRE CD14 C10orf105

1.15e-041951736b95a631d54c6cf85e48e1e638703206aaaebc073
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTCRA NR4A3 FMNL3 CORO1A ZNF469 PTPRE

1.18e-041961736787088ce800d7148bad7265a971797da597b029a
ToppCelldistal-2-Hematologic-EREG+_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA6B MBOAT7 NR4A3 HPSE CORO1A PTPRE

1.22e-0419717366fcca7c071e35786b715adeb18be317d34315d7e
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ATP7B ARHGAP39 SMPDL3B UMODL1 PPP1R3F PCK1

1.22e-041971736fd76cc5e12c7e7943a48f739e4f0626ff7211f51
ToppCell(2)_Fibroblasts-(23)_Fibro-4|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MBNL1 KIAA1549 LGALS3 C10orf105 TNXB AHNAK2

1.22e-041971736a183919023a4aca90a06be0e5e89c817b38c5574
ToppCellBAL-Mild-Myeloid-MoAM|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NPL HPSE LGALS3 GLMP PTPRE CD14

1.22e-0419717360f40dd3530eb8d02e79b32f942efe3b65b8f6ee6
ToppCellBAL-Mild-Myeloid-MoAM|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

NPL HPSE LGALS3 GLMP PTPRE CD14

1.22e-041971736a6aa5991d566c28440f7e24a30933e69669064f2
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NPL IL10RB SEMA6B LGALS3 GLMP CD14

1.25e-041981736641e7be258303bb9782d19fcf8693f317581d3b8
ToppCellNS-critical-LOC-Myeloid|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NPL FNDC3B MBOAT7 HPSE PTPRE CD14

1.25e-04198173658f2bc88d92550fb0b7c2e46c63c49ec6777001c
ToppCellLPS_IL1RA_TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Platelets|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NPL ILK PTCRA ITGA2 HPSE LMAN1L

1.28e-041991736b68648b4559e452656dc9e6a0974233e842f5e0d
ToppCellLung_Parenchyma-Control-Myeloid-MoAM-MoAM-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA6B NR4A3 HPSE CORO1A PTPRE CD14

1.32e-042001736390f9429feae991b8524e2815d8fcd4914c74459
ToppCellLung_Parenchyma-Control-Myeloid-MoAM-MoAM|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEMA6B NR4A3 HPSE CORO1A PTPRE CD14

1.32e-042001736f7e9b4a8ededb116774528b38ea3381b6f05915c
ToppCellLung_Parenchyma-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SEMA6B NR4A3 HPSE CORO1A PTPRE CD14

1.32e-042001736d98c523ac0e4767aaeef50cae142513d115212ab
ToppCellParenchyma_Control_(B.)-Immune-TX-MoAM-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

SEMA6B NR4A3 HPSE CORO1A PTPRE CD14

1.32e-04200173659b2ebb69699c9bebf8c2697eb678fdccd0a998c
ToppCelldistal-Hematologic-EREG+_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA6B NR4A3 PPP1R3G ZZEF1 ZNF469 SCNN1D

1.32e-0420017367809c74a2e52768854b66a135522138281bc4449
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHA4 ETV4 SEC31B NCOR2 TNXB SLC26A6

1.32e-042001736f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Htra1_(Htra1)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACOX2 WDR93 C10orf105 FOXP3

1.34e-04671734e6d051404f095ab9ca95fa6e5ecf0905573a5a63
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Htra1_(Htra1)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACOX2 WDR93 C10orf105 FOXP3

1.34e-046717348502da9042f40e0a44354776bb507e18ef0cda43
ToppCellEntopeduncular-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Htra1_(Htra1)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACOX2 WDR93 C10orf105 FOXP3

1.34e-046717343a3a3e76f67c1d33bd7b1d0d94c522ad1e1192f8
DrugAzacyclonol [115-46-8]; Up 200; 15uM; HL60; HG-U133A

SEMA6B CRYBG2 COMT PTCRA ADGRB2 CHN2 PRX MST1R PLD2 TRAPPC9 FOXP3

3.02e-07198170112020_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Up 200; 12.2uM; HL60; HT_HG-U133A

PTCRA DBT MAST2 ZZEF1 ZCCHC4 DSTYK SLCO1A2 DGKI PLAGL1 PLD2

1.99e-06193170103015_UP
DrugCimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HG-U133A

CRYBG2 PATZ1 ST6GAL1 ZZEF1 CHN2 PRX NCOR2 MTF1 STOML1 PLD2

2.18e-06195170101884_UP
DrugClopamide [636-54-4]; Up 200; 11.6uM; HL60; HG-U133A

SEMA6B CRYBG2 COMT PATZ1 ADGRB2 ZZEF1 CHN2 MTF1 PLD2 TRAPPC9

2.62e-06199170101605_UP
DrugSuramin sodium salt; Down 200; 10uM; PC3; HT_HG-U133A

CRYBG2 ST6GAL1 RBM48 ZZEF1 NCOR1 NCOR2 NYNRIN TESK2 MMP17

1.59e-0519417097529_DN
DrugAmphotericin B [1397-89-3]; Down 200; 4.4uM; MCF7; HT_HG-U133A

PLXNA3 ATP7B FPGS KATNB1 POGZ MAST2 ZNF668 ZFYVE9 DSTYK

1.59e-0519417093303_DN
Drugbromate

CA9 RNF112 ITGA2 UBASH3A

1.63e-05211704CID000024445
DrugTroleandomycin [2751-09-9]; Down 200; 5uM; MCF7; HT_HG-U133A

ITGA2 DBT ITPKB ZNF668 ZFYVE9 SMPDL3B PTPRE CSPP1 SLC26A6

1.73e-0519617091465_DN
DrugLobeline alpha (-) hydrochoride [134-63-4]; Up 200; 10.6uM; HL60; HG-U133A

CRYBG2 COMT ADGRB2 ITGA2 CHN2 MTF1 EGR4 PLD2 TRAPPC9

1.73e-0519617091770_UP
DrugAltretamine [654-05-6]; Up 200; 19uM; HL60; HT_HG-U133A

ATP7B MBNL1 ST6GAL1 ZZEF1 ZNF668 ZFYVE9 STOML1 ZNF79 PLD2

1.80e-0519717093090_UP
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

3.30e-0521702DOID:0110471 (implicated_via_orthology)
DiseaseVesico-Ureteral Reflux

DSTYK TNXB

1.96e-0441702C0042580
Diseasecitrulline measurement

GLP2R HMCN2 PTPRE

1.99e-04201703EFO_0009777
Diseaseheel bone mineral density, urate measurement

CNTN4 ST6GAL1 CHN2 CXXC4 PLAGL1 SON

6.74e-041821706EFO_0004531, EFO_0009270
DiseaseDisorder of amino acid metabolism

DBT QDPR

9.03e-0481702cv:C0002514
DiseaseEhlers-Danlos syndrome (is_implicated_in)

SLC39A13 TNXB

1.16e-0391702DOID:13359 (is_implicated_in)
DiseaseMalignant neoplasm of liver

ATP7B CHN2 NCOR1 SPATA21 ADAMTS17

1.42e-031421705C0345904
DiseaseLiver neoplasms

ATP7B CHN2 NCOR1 SPATA21 ADAMTS17

1.42e-031421705C0023903
Diseasegamma-glutamylleucine measurement

MBNL1 GGT1

2.47e-03131702EFO_0021140
DiseaseConnective Tissue Diseases

SLC39A13 ZNF469

2.47e-03131702C0009782
Diseasehepatocellular carcinoma (implicated_via_orthology)

FOXM1 CAD ATP7B

2.85e-03491703DOID:684 (implicated_via_orthology)
Diseasebiliary atresia (is_marker_for)

GGT1 CD14

2.87e-03141702DOID:13608 (is_marker_for)
Diseaseautism spectrum disorder (is_implicated_in)

COMT MBD6

3.76e-03161702DOID:0060041 (is_implicated_in)
DiseaseCondition, Preneoplastic

FOXM1 CHN2 MGMT ATP5F1B

3.82e-031101704C0282313
DiseasePrecancerous Conditions

FOXM1 CHN2 MGMT ATP5F1B

3.82e-031101704C0032927
DiseaseMalignant neoplasm of breast

FOXM1 FNDC3B DDX59 ATP7B COMT TP53I3 ETV4 CUBN HPSE NCOR1 ZNF668 SPATA21 PLD2 FOXP3

3.84e-03107417014C0006142
Diseaseesophageal carcinoma, gastric carcinoma

MAST2 TRPM1

4.24e-03171702EFO_0000178, EFO_0002916
Diseaseprogression free survival, ovarian carcinoma

FMNL3 ARMH4

4.75e-03181702EFO_0001075, EFO_0004920
DiseaseDisorder of organic acid metabolism

MCCC1 DBT

4.75e-03181702cv:C1263739
Diseaseadverse effect, response to xenobiotic stimulus

COL13A1 CENPC FMNL3

4.82e-03591703EFO_0009658, GO_0009410

Protein segments in the cluster

PeptideGeneStartEntry
FPMGISTLAPILQPL

UMODL1

476

Q5DID0
PGGGLIIIDSMPDIR

UNC13A

481

Q9UPW8
LAMPLPLGPATQVPA

LINC00311

21

Q8N616
MPPGDLCGPTLLLDV

AHRR

521

A9YTQ3
NILVPMAASPGLGEP

ADGRB2

1301

O60241
LLQEQGLLSMPPEPG

AEN

46

Q8WTP8
PLIGDMPLVGALSIF

ESYT2

306

A0FGR8
TPLPGIIIGDIGPKM

ACOX2

231

Q99424
MQPLEVGLVPAPAGE

CYB561D1

1

Q8N8Q1
IPIAAGVFMPIGIVL

ATP7B

1336

P35670
IMVGEPSISPALPAL

ARMH4

566

Q86TY3
PAGLEPVVVGMLILA

AQP10

186

Q96PS8
LGPPTPLILRNDGVM

CNTN4

206

Q8IWV2
IPDGGLMLPLREPVV

CORO1A

111

P31146
DAGPEGRLLPLPMPT

AHDC1

406

Q5TGY3
GRLLPLPMPTGLVAA

AHDC1

411

Q5TGY3
LPMPTGLVAALAEPP

AHDC1

416

Q5TGY3
MPPGAAAIAVLPVTL

QDPR

171

P09417
MCDGALLPPLVLPVL

ADAMTS17

1

Q8TE56
PIKIPVGPETLGRIM

ATP5F1B

131

P06576
SVQLTLPPGLEMALG

CA9

201

Q16790
LGKLMDPGSLPPLDS

ETV4

36

P43268
ALPMIAGPPIAGLLR

SLC16A2

456

P36021
ELGAMPPGLRPTLGV

RASIP1

736

Q5U651
GPAVIGPSLPLALAM

RBM42

276

Q9BTD8
NPTGNEIMIGPLLPD

RBM48

301

Q5RL73
MGPLGSPLSKIGIEL

PCK1

146

P35558
VPEGLLMPIPEGLTL

TP53I3

101

Q53FA7
INMILPTVPALPGPG

RFX5

381

P48382
LPLPMPGPVVRAFSE

ARHGAP39

591

Q9C0H5
GLGAPVRLMAPTPVL

PUM2

456

Q8TB72
RSLMPQPLGDGITIP

KIAA1549

286

Q9HCM3
ELGPPVVISPSLSGM

ABHD14B

101

Q96IU4
MAPRPLGPLVLALGG

ARL10

1

Q8N8L6
PVIMPPEVAIGALGS

DBT

411

P11182
AKAPVGPVTMGLPLP

NCOR2

1141

Q9Y618
LVPEGPLPGHLVDMS

PCDHB13

726

Q9Y5F0
GMLGALPLPLSLGQP

MBD6

536

Q96DN6
VGGTPFPSLAPPIML

PTCRA

21

Q6ISU1
MEPLCPLLLVGFSLP

PTPRE

1

P23469
LVMVAPSGARLGPLP

FOXP3

76

Q9BZS1
MGIARTSPILPLPDV

GARIN4

71

Q8IYT1
SPLTLLCEAMGIPPP

HMCN2

2376

Q8NDA2
MPAVSGPGPLFCLLL

LMAN1L

1

Q9HAT1
ASGTTPVPQLPLLLM

SMPDL3B

431

Q92485
VPAPAAVLGGPEPLM

MGMT

46

P16455
PLPGGVVPRMLITIL

LGALS3

121

P17931
PLITDMLAAPPSVGV

KATNB1

591

Q9BVA0
GMLEEPLLGPLQPLS

CARF

186

Q8N187
MKTVLLVGGLPLPPQ

DDX59

301

Q5T1V6
CLAGLLGPMHPVDIP

IBA57-DT

56

B1ANH7
PPGPLVLMVAVVATS

LTK

421

P29376
VLNSLLPMELGPTPE

LTK

786

P29376
ILPSGDLLIPVGVMQ

PLXNA3

686

P51805
ALGEMVSPRIAPLPP

CSPP1

521

Q1MSJ5
GLLSQPGPSSLMPVL

NOL6

1036

Q9H6R4
GTLQPPMVLLDFPPL

COG8

421

Q96MW5
KGPTLGLLPDVPSLM

MBOAT7

136

Q96N66
EMTAPLPPLSGLALF

LMAN2L

301

Q9H0V9
PTLTDLPLLPGVPMA

LRRC46

231

Q96FV0
NLMSGILGLAPFPGP

EGR4

206

Q05215
MGPERTGAAPLPLLL

ITGA2

1

P17301
GDPLKRPLLGIVQPM

DSTYK

891

Q6XUX3
LAPIGIRVMTIAPGL

HSD17B10

186

Q99714
LMEKPLRPGSSLGLP

HPSE

511

Q9Y251
LGKLPGGLPAMLATP

PKD1L2

1051

Q7Z442
LSGPSPMIEIRNPLG

HMCN1

251

Q96RW7
VMAIEAGLGDLPLLP

GRIN3A

151

Q8TCU5
TTLLGLIPAPSMVPA

POM121C

636

A8CG34
LPVLPGVDRLPMVAG

PATZ1

226

Q9HBE1
LLPLVMLVISPIPGA

PRSS36

6

Q5K4E3
LLGLIPAPSMVPATD

POM121

661

Q96HA1
LVGVNVPEIPCIPML

FBXO38

196

Q6PIJ6
NLGIVFGPTLMRPPE

CHN2

426

P52757
MPEAPPLLLAAVLLG

COMT

1

P21964
DEMPAPLTIAGPVLL

CUBN

3001

O60494
TMPPLPLEATGLALS

CD14

131

P08571
GLLPGVHELPMGIPA

GLP2R

16

O95838
TAPSLIQPLGMVPLI

E2F8

486

A0AVK6
MVNLGIPLGDPLQPT

CENPC

811

Q03188
PPGMPDLVVEQASGI

DGKI

866

O75912
LILPENEPGSSIMPG

FH

356

P07954
IPLELPPLLNGEVAM

FNDC3B

11

Q53EP0
LARVGPAELSEGMPP

FMNL3

486

Q8IVF7
VDMLVPSVGLIIPPP

DSP

501

P15924
GAMARTELLVPLPGP

CRYBG2

136

Q8N1P7
GMKVALEGLRPTIPP

ILK

401

Q13418
PALGGISLPPGVIVM

CXXC4

71

Q9H2H0
NQPMLPIGLSDIPGE

CSNK2B

116

P67870
GCLLVSALGMVPPPE

IL10RB

11

Q08334
PPVDGLSPLVLGIMA

GLMP

361

Q8WWB7
PAEILPTAPMLVTGN

MBNL1

146

Q9NR56
GIIFIGPPPSAIRDM

MCCC1

146

Q96RQ3
GPMVPSLLTGITLGP

MAST2

1556

Q6P0Q8
PDPLGLMDLSTTPLQ

FOXM1

651

Q08050
PMLEALEEGGPPLTL

FPGS

281

Q05932
MPTGFVAPILCVLLP

DDX17

1

Q92841
EIRTLALMGPPGLPG

COL13A1

456

Q5TAT6
PFAPGKPLEMGILSE

FAM186A

1771

A6NE01
PGGLAPTVLAPMPLA

GRIPAP1

176

Q4V328
EIIQPLLDMAAGIPP

SCAF8

126

Q9UPN6
LLDMAAGIPPPVVTP

SCAF8

131

Q9UPN6
PHLPRVMLPGVLAGV

SCNN1D

771

P51172
LMVGLSGVFPLLVIP

SLC39A13

76

Q96H72
GITPINPMIPGLGLV

ENOX1

86

Q8TC92
LPGLSVMGVCLLIPG

NDUFA1

6

O15239
PDLVRPLQMTIPGGT

FAM120B

661

Q96EK7
TLAYLVPGPPGSLMV

NYNRIN

106

Q9P2P1
SNFLPDLPGMIDLPG

MED19

106

A0JLT2
PLLDPPMKAVPTVAG

NR4A3

171

Q92570
TLVSGIPMGPPRLPL

NPL

271

Q9BXD5
ITIAMPPGAPDGVLP

USH2A

2426

O75445
PLAMGTVSLGQLPLP

PLAGL1

426

Q9UM63
SMPCPVLLGPALDLG

SPATA21

161

Q7Z572
MALSLPLGPRLGSEP

SYNE4

1

Q8N205
GLPPTLVMAVPATVI

SLC25A40

106

Q8TBP6
IPGLPALLSMLFAPV

TDRD9

1221

Q8NDG6
PGAPGPLVAATMLLL

MMP17

571

Q9ULZ9
GFLTIEQIAMLPPPA

MRGPRF

31

Q96AM1
METLPGLLQRPDPGA

RIIAD1

1

A6NNX1
GTRASMVLLPGPPLE

PLEKHA4

341

Q9H4M7
LPMPIPGELLTLIGA

SLC26A6

291

Q9BXS9
VEAGIPSGRMLEPLP

ITPKB

466

P27987
TEPLPAMVQTLPLGA

MTF1

526

Q14872
PLILTQNPAPGLGTM

POGZ

106

Q7Z3K3
GIIDLTNMPPTILVP

NCOR1

1651

O75376
VPALQPIMSPGLLSP

SATB2

286

Q9UPW6
TLAGLIPFVAPPLVM

TMEM69

101

Q5SWH9
IQPNPPSSGMLGIII

ST6GAL1

316

P15907
MEPIGARLSLEAPGP

PPP1R3G

1

B7ZBB8
IVRGMGETPILPLGI

SLCO1A2

166

P46721
APVMSLTPELQGILP

SEC31B

1021

Q9NQW1
IATLGEIPQPPLMGN

SREK1

41

Q8WXA9
PPGAMQELLGALEPL

PRR12

876

Q9ULL5
LTPGPFLLGMLSQLP

STRC

591

Q7RTU9
PGMRLPETQVLPGEI

AHNAK2

5311

Q8IVF2
PGTLAEATDPLPMLI

C10orf105

26

Q8TEF2
GGAGVPPEALLAPLM

SEMA6B

671

Q9H3T3
VPMGTPTPLEPLVAL

ZNF668

596

Q96K58
SLQPPELIGAMLEPT

XAGE2

16

Q96GT9
QMIESIGGLLGPPLS

SLC16A13

346

Q7RTY0
ELGLGPQPMAPRELP

RNF112

41

Q9ULX5
LMALAILSPCPPLVG

SLC52A1

356

Q9NWF4
IRTPQGPGMVLLLPF

STOML1

96

Q9UBI4
AGLRMPPLGISLPQV

PRX

1141

Q9BXM0
RPPPSGSQGLLEEML

TNKS1BP1

1446

Q9C0C2
MGPLSVVIVTAPLPP

TNXB

1551

P22105
PPPVSQVDAAIGLLM

THAP1

106

Q9NVV9
MLQDTGISLLIPPGA

UNC5CL

116

Q8IV45
LGRVMVELEALLPPP

PPP1R3F

131

Q6ZSY5
FMLVSLDEGPGPPIK

USP9Y

2206

O00507
PPGFPGLETMLPLLL

CAD

1701

P27708
PLALVEVGMTLPVPQ

nan

86

Q6Q795
GPPGVLLTRPVILAM

UNC5A

506

Q6ZN44
GEMGASPGLLIPEQP

ZNF469

1226

Q96JG9
NPGLKVIMGILLPPT

TRPM1

746

Q7Z4N2
MAEAEGSSLLLLPPP

TMEM222

1

Q9H0R3
DLGGPLPTDPMLGLA

TSPAN10

111

Q9H1Z9
IPATALLPTMTPDGL

U2AF2

116

P26368
AVAPVPALPGMVLIF

WDR93

526

Q6P2C0
IIMVTDPPFGGLVEP

ZCCHC4

271

Q9H5U6
GLLAAMLPPLKSGPT

ZZEF1

2091

O43149
LTPGPFLLGMLSQLP

STRCP1

591

A6NGW2
GTMEPIALPGGLTLP

TRAPPC9

516

Q96Q05
LVFDLDAPGPGTMPL

TESK2

426

Q96S53
IPPQPMEGLGFLDAL

PPP1R10

281

Q96QC0
LLPPLGSKEGMIPLE

PLD2

916

O14939
MLEEGVLPSPGPALP

ZNF79

1

Q15937
PNVLALIGIMLPPEG

MST1R

1141

Q04912
LIGIMLPPEGLPHVL

MST1R

1146

Q04912
QELPGLPAPSMGLEP

SON

451

P18583
LLGQPEATMVLELPG

SON

536

P18583
PVGSAMNLIPEDGLP

ZFYVE9

891

O95405
MNLIPEDGLPPILIS

ZFYVE9

896

O95405
GPETKPVLMALAEGP

TRIM28

571

Q13263
PPEGLPGFNSGVMLL

XXYLT1

281

Q8NBI6
SPSLLEPLLAMGFPV

UBASH3A

21

P57075
GMPLTVVAPAELVVP

ZNF518B

326

Q9C0D4
MPSAPLSGPVLALIL

GGT1

276

P19440
MAPAPLGVPEEQLLG

LRIG2

1

O94898
PSPMLLPEGLSSQAL

NACAD

91

O15069