Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9C SELP LGALS9B LGALS9

1.85e-0620914GO:0070492
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B LGALS9

3.16e-067913GO:0048030
GeneOntologyMolecularFunctiongalactoside binding

LGALS9C LGALS9B LGALS9

7.54e-069913GO:0016936
GeneOntologyMolecularFunctionmolybdenum ion binding

XDH MOCOS

3.04e-046912GO:0030151
GeneOntologyMolecularFunctionfatty acid elongase activity

ELOVL5 ELOVL2

4.25e-047912GO:0009922
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

NDST1 ACER1 HDAC5 SIRT5

5.14e-0481914GO:0016811
GeneOntologyMolecularFunctiondeacetylase activity

NDST1 HDAC5 SIRT5

8.01e-0440913GO:0019213
GeneOntologyMolecularFunctionMHC protein complex binding

LILRA2 HLA-DRB4 HLA-DRB5

8.61e-0441913GO:0023023
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

3.31e-074913GO:0043322
GeneOntologyBiologicalProcessregulation of oxidoreductase activity

LGALS9C FGF23 SPHK2 LGALS9B SIRT5 LGALS9

1.92e-0684916GO:0051341
GeneOntologyBiologicalProcessregulation of natural killer cell degranulation

LGALS9C LGALS9B LGALS9

4.58e-068913GO:0043321
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

LGALS9C SELP LGALS9B CRB1 LGALS9

8.59e-0663915GO:0007157
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

3.64e-0515913GO:2000562
GeneOntologyBiologicalProcessnegative regulation of natural killer cell activation

LGALS9C LGALS9B LGALS9

3.64e-0515913GO:0032815
GeneOntologyBiologicalProcessnegative regulation of secretion by cell

LGALS9C FGF23 LGALS9B PTGER3 GABBR1 LGALS9 CRY1

4.54e-05214917GO:1903531
GeneOntologyBiologicalProcesspositive regulation of oxidoreductase activity

LGALS9C FGF23 LGALS9B LGALS9

5.02e-0546914GO:0051353
GeneOntologyBiologicalProcessnegative regulation of leukocyte degranulation

LGALS9C LGALS9B LGALS9

5.40e-0517913GO:0043301
GeneOntologyBiologicalProcessnatural killer cell degranulation

LGALS9C LGALS9B LGALS9

6.46e-0518913GO:0043320
GeneOntologyBiologicalProcessnegative regulation of alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

7.65e-0519913GO:0046642
GeneOntologyBiologicalProcesspositive regulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

7.65e-0519913GO:1900426
GeneOntologyBiologicalProcessregulation of T cell chemotaxis

LGALS9C LGALS9B LGALS9

8.97e-0520913GO:0010819
GeneOntologyBiologicalProcessnegative regulation of secretion

LGALS9C FGF23 LGALS9B PTGER3 GABBR1 LGALS9 CRY1

9.10e-05239917GO:0051048
GeneOntologyBiologicalProcessregulation of natural killer cell differentiation

LGALS9C LGALS9B LGALS9

1.04e-0421913GO:0032823
GeneOntologyBiologicalProcessregulation of leukocyte degranulation

LGALS9C SPHK2 LGALS9B LGALS9

1.73e-0463914GO:0043300
GeneOntologyBiologicalProcessregulation of defense response to bacterium

LGALS9C LGALS9B LGALS9

2.01e-0426913GO:1900424
GeneOntologyBiologicalProcesspositive regulation of interleukin-6 production

LGALS9C SPHK2 LILRA2 LGALS9B LGALS9

2.07e-04122915GO:0032755
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

2.51e-0428913GO:2000561
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor production

LGALS9C SPHK2 LILRA2 LGALS9B LGALS9

3.08e-04133915GO:0032760
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell proliferation

LGALS9C LGALS9B LGALS9

3.09e-0430913GO:0035739
GeneOntologyBiologicalProcessregulation of lymphocyte chemotaxis

LGALS9C LGALS9B LGALS9

3.41e-0431913GO:1901623
GeneOntologyBiologicalProcesspositive regulation of regulatory T cell differentiation

LGALS9C LGALS9B LGALS9

3.41e-0431913GO:0045591
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor superfamily cytokine production

LGALS9C SPHK2 LILRA2 LGALS9B LGALS9

3.54e-04137915GO:1903557
GeneOntologyBiologicalProcessregulation of lymphocyte migration

LGALS9C WASL LGALS9B LGALS9

3.75e-0477914GO:2000401
GeneOntologyBiologicalProcessnegative regulation of regulated secretory pathway

LGALS9C LGALS9B LGALS9

3.76e-0432913GO:1903306
GeneOntologyBiologicalProcessfatty acid elongation, polyunsaturated fatty acid

ELOVL5 ELOVL2

3.99e-047912GO:0034626
GeneOntologyBiologicalProcessfatty acid elongation, monounsaturated fatty acid

ELOVL5 ELOVL2

3.99e-047912GO:0034625
GeneOntologyBiologicalProcessfatty acid elongation, unsaturated fatty acid

ELOVL5 ELOVL2

3.99e-047912GO:0019368
GeneOntologyBiologicalProcessregulation of secretion by cell

LGALS9C FGF23 KDM5B SPHK2 LGALS9B GRIN2B CADPS2 PTGER3 GABBR1 LGALS9 CRY1

4.09e-047409111GO:1903530
GeneOntologyBiologicalProcessT cell chemotaxis

LGALS9C LGALS9B LGALS9

4.12e-0433913GO:0010818
GeneOntologyBiologicalProcessregulation of macrophage activation

LGALS9C LGALS9B LRFN5 LGALS9

4.55e-0481914GO:0043030
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

LGALS9C SELP FAT2 LGALS9B LRFN5 CRB1 LGALS9

4.72e-04313917GO:0098742
GeneOntologyBiologicalProcessreceptor clustering

LGALS9C LGALS9B GRIN2B LGALS9

4.99e-0483914GO:0043113
GeneOntologyBiologicalProcessfatty acid elongation, saturated fatty acid

ELOVL5 ELOVL2

5.30e-048912GO:0019367
GeneOntologyBiologicalProcessnegative regulation of response to biotic stimulus

LGALS9C LILRA2 LGALS9B TRIM38 LGALS9

5.52e-04151915GO:0002832
GeneOntologyBiologicalProcessregulation of T cell differentiation in thymus

LGALS9C LGALS9B LGALS9

5.79e-0437913GO:0033081
GeneOntologyBiologicalProcesspositive regulation of interleukin-1 production

LGALS9C LILRA2 LGALS9B LGALS9

6.23e-0488914GO:0032732
GeneOntologyBiologicalProcessnatural killer cell differentiation

LGALS9C LGALS9B LGALS9

6.27e-0438913GO:0001779
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated cytotoxicity

LGALS9C LGALS9B LGALS9

7.29e-0440913GO:0045953
GeneOntologyBiologicalProcessnegative regulation of CD4-positive, alpha-beta T cell activation

LGALS9C LGALS9B LGALS9

7.29e-0440913GO:2000515
GeneOntologyBiologicalProcessnegative regulation of natural killer cell mediated immunity

LGALS9C LGALS9B LGALS9

7.84e-0441913GO:0002716
GeneOntologyBiologicalProcesspositive regulation of T cell migration

LGALS9C LGALS9B LGALS9

7.84e-0441913GO:2000406
GeneOntologyBiologicalProcessregulation of secretion

LGALS9C FGF23 KDM5B SPHK2 LGALS9B GRIN2B CADPS2 PTGER3 GABBR1 LGALS9 CRY1

7.90e-048019111GO:0051046
GeneOntologyBiologicalProcesspositive regulation of cell activation

LGALS9C SELP SPHK2 LILRA2 LGALS9B HLA-DRB4 HLA-DRB5 LGALS9

8.31e-04449918GO:0050867
GeneOntologyBiologicalProcessnatural killer cell activation involved in immune response

LGALS9C LGALS9B LGALS9

8.42e-0442913GO:0002323
GeneOntologyBiologicalProcesspositive regulation of macrophage activation

LGALS9C LGALS9B LGALS9

8.42e-0442913GO:0043032
GeneOntologyBiologicalProcessalpha-linolenic acid metabolic process

ELOVL5 ELOVL2

8.47e-0410912GO:0036109
GeneOntologyBiologicalProcesspositive regulation of SMAD protein signal transduction

LGALS9C LGALS9B LGALS9

9.02e-0443913GO:0060391
GeneOntologyBiologicalProcessnegative regulation of exocytosis

LGALS9C LGALS9B LGALS9

1.03e-0345913GO:0045920
MousePhenoincreased circulating xanthine level

XDH MOCOS

2.92e-052762MP:0031490
MousePhenoabnormal circulating xanthine level

XDH MOCOS

2.92e-052762MP:0031488
MousePhenoincreased susceptibility to induced arthritis

LGALS9C SELP LGALS9B LGALS9

4.16e-0536764MP:0003724
MousePhenoincreased circulating hypoxanthine level

XDH MOCOS

8.72e-053762MP:0031487
MousePhenoabnormal circulating hypoxanthine level

XDH MOCOS

8.72e-053762MP:0031485
MousePhenoincreased urine hypoxanthine level

XDH MOCOS

8.72e-053762MP:0031484
MousePhenoabnormal urine hypoxanthine level

XDH MOCOS

8.72e-053762MP:0031482
MousePhenoenhanced humoral immune response

LGALS9C LGALS9B LGALS9

9.94e-0517763MP:0020155
MousePhenoincreased T-helper 1 cell number

LGALS9C LGALS9B LGALS9

1.41e-0419763MP:0008086
MousePhenoabnormal urine xanthine level

XDH MOCOS

1.74e-044762MP:0031480
MousePhenoincreased urine xanthine level

XDH MOCOS

1.74e-044762MP:0031479
MousePhenoincreased spleen germinal center size

LGALS9C LGALS9B LGALS9

2.53e-0423763MP:0008483
MousePhenoabnormal lymph node germinal center morphology

LGALS9C LGALS9B LGALS9

2.53e-0423763MP:0008522
MousePhenoabnormal T-helper 1 cell number

LGALS9C LGALS9B LGALS9

2.88e-0424763MP:0008085
MousePhenoabnormal lymph node secondary follicle morphology

LGALS9C LGALS9B LGALS9

3.26e-0425763MP:0002346
Domain-

LGALS9C FAT2 LGALS9B PAPPA USH2A CRB1 LGALS9

4.34e-07959272.60.120.200
DomainConA-like_dom

LGALS9C FAT2 LGALS9B PAPPA USH2A TRIM38 CRB1 LGALS9

1.26e-05219928IPR013320
DomainGalectin_CRD

LGALS9C LGALS9B LGALS9

5.04e-0515923IPR001079
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

5.04e-0515923PF00337
DomainGal-bind_lectin

LGALS9C LGALS9B LGALS9

5.04e-0515923SM00908
DomainGALECTIN

LGALS9C LGALS9B LGALS9

5.04e-0515923PS51304
DomainGLECT

LGALS9C LGALS9B LGALS9

5.04e-0515923SM00276
DomainSushi

SELP PAPPA CSMD3 GABBR1

1.25e-0452924PF00084
DomainLamGL

PAPPA USH2A

1.43e-044922SM00560
DomainLamG-like

PAPPA USH2A

1.43e-044922IPR006558
DomainCCP

SELP PAPPA CSMD3 GABBR1

1.44e-0454924SM00032
DomainSUSHI

SELP PAPPA CSMD3 GABBR1

1.66e-0456924PS50923
DomainSushi_SCR_CCP_dom

SELP PAPPA CSMD3 GABBR1

1.78e-0457924IPR000436
DomainELO

ELOVL5 ELOVL2

4.96e-047922PS01188
DomainELO

ELOVL5 ELOVL2

4.96e-047922PF01151
DomainELO_fam

ELOVL5 ELOVL2

4.96e-047922IPR002076
DomainMHC_II_b_N

HLA-DRB4 HLA-DRB5

6.59e-048922PD000328
DomainMHC_II_b_N

HLA-DRB4 HLA-DRB5

8.45e-049922IPR000353
DomainMHC_II_beta

HLA-DRB4 HLA-DRB5

8.45e-049922SM00921
DomainMHC_II_beta

HLA-DRB4 HLA-DRB5

8.45e-049922PF00969
DomainLAM_G_DOMAIN

FAT2 USH2A CRB1

8.61e-0438923PS50025
DomainLaminin_G_2

FAT2 USH2A CRB1

1.00e-0340923PF02210
DomainTPR_7

TTC28 TONSL

1.05e-0310922PF13176
DomainLamG

FAT2 USH2A CRB1

1.32e-0344923SM00282
Domain-

KLHL7 KLHDC3 LCMT2

1.70e-03489232.120.10.80
DomainKelch_2

KLHDC3 LCMT2

1.81e-0313922IPR011498
DomainKelch_2

KLHDC3 LCMT2

1.81e-0313922PF07646
DomainMHC_II_a/b_N

HLA-DRB4 HLA-DRB5

2.10e-0314922IPR014745
Domain-

HLA-DRB4 HLA-DRB5

2.10e-03149223.10.320.10
DomainKelch-typ_b-propeller

KLHL7 KLHDC3 LCMT2

2.52e-0355923IPR015915
DomainLaminin_N

LAMB3 USH2A

2.75e-0316922IPR008211
DomainLamNT

LAMB3 USH2A

2.75e-0316922SM00136
DomainLAMININ_NTER

LAMB3 USH2A

2.75e-0316922PS51117
DomainLaminin_N

LAMB3 USH2A

2.75e-0316922PF00055
DomainLaminin_G

FAT2 USH2A CRB1

2.93e-0358923IPR001791
Domain-

DENND5B LIPC

4.74e-03219222.60.60.20
DomainPLAT

DENND5B LIPC

4.74e-0321922PF01477
DomainPLAT/LH2_dom

DENND5B LIPC

4.74e-0321922IPR001024
DomainPLAT

DENND5B LIPC

4.74e-0321922PS50095
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9C LGALS9B LGALS9

1.79e-08392329458010
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9C LGALS9B LGALS9

1.79e-08392319776007
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9C LGALS9B LGALS9

1.79e-08392326582205
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9C LGALS9B LGALS9

1.79e-0839239153289
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B LGALS9

1.79e-08392333316546
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9C LGALS9B LGALS9

1.79e-08392318974023
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9C LGALS9B LGALS9

1.79e-0839239038233
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9C LGALS9B LGALS9

1.79e-08392323144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9C LGALS9B LGALS9

1.79e-08392329651447
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B LGALS9

1.79e-08392328704475
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9C LGALS9B LGALS9

1.79e-08392321146220
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B LGALS9

1.79e-08392323836896
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B LGALS9

1.79e-0839237890611
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9C LGALS9B LGALS9

1.79e-08392322341088
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9C LGALS9B LGALS9

1.79e-08392328990062
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B LGALS9

1.79e-08392332380082
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B LGALS9

1.79e-08392323667648
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9C LGALS9B LGALS9

1.79e-08392318579572
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B LGALS9

1.79e-08392328877989
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B LGALS9

1.79e-08392319800850
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9C LGALS9B LGALS9

1.79e-08392338987795
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9C LGALS9B LGALS9

1.79e-08392316990264
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9C LGALS9B LGALS9

1.79e-08392318005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9C LGALS9B LGALS9

1.79e-08392323585851
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9C LGALS9B LGALS9

1.79e-08392324477688
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9C LGALS9B LGALS9

1.79e-08392329433546
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B LGALS9

1.79e-08392337105392
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B LGALS9

1.79e-08392336479526
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B LGALS9

1.79e-08392323242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B LGALS9

1.79e-08392319851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B LGALS9

1.79e-08392333923930
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9C LGALS9B LGALS9

1.79e-08392325898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9C LGALS9B LGALS9

1.79e-08392331937306
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9C LGALS9B LGALS9

1.79e-08392321426359
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B LGALS9

1.79e-08392331969388
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9C LGALS9B LGALS9

1.79e-08392318282810
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9C LGALS9B LGALS9

1.79e-08392335241678
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9C LGALS9B LGALS9

1.79e-08392324083426
Pubmed

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9C LGALS9B LGALS9

1.79e-08392337279535
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9C LGALS9B LGALS9

1.79e-08392325931247
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9C LGALS9B LGALS9

1.79e-08392322627368
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9C LGALS9B LGALS9

1.79e-08392333153471
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9C LGALS9B LGALS9

1.79e-08392322052881
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9C LGALS9B LGALS9

1.79e-08392317560833
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9C LGALS9B LGALS9

1.79e-08392335643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9C LGALS9B LGALS9

1.79e-08392323408620
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9C LGALS9B LGALS9

7.15e-08492338686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9C LGALS9B LGALS9

7.15e-08492322677125
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9C LGALS9B LGALS9

7.15e-08492319234217
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9C LGALS9B LGALS9

7.15e-08492335715604
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9C LGALS9B LGALS9

7.15e-08492319017954
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9C LGALS9B LGALS9

7.15e-08492333963043
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9C LGALS9B LGALS9

7.15e-08492336459823
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9C LGALS9B LGALS9

7.15e-08492333107565
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9C LGALS9B LGALS9

7.15e-08492329611821
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9C LGALS9B LGALS9

7.15e-08492330763585
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9C LGALS9B LGALS9

7.15e-08492333727589
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9C LGALS9B LGALS9

7.15e-08492319362679
Pubmed

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.

LGALS9C LGALS9B LGALS9

7.15e-08492325578313
Pubmed

Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.

LGALS9C LGALS9B LGALS9

7.15e-08492329844236
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9C LGALS9B LGALS9

7.15e-08492320463811
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9C LGALS9B LGALS9

7.15e-08492332855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9C LGALS9B LGALS9

7.15e-08492323657851
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9C LGALS9B LGALS9

7.15e-08492318826117
Pubmed

The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.

LGALS9C LGALS9B LGALS9

7.15e-08492324333756
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9C LGALS9B LGALS9

7.15e-08492338853593
Pubmed

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

LGALS9C LGALS9B LGALS9

7.15e-08492324958847
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS9C LGALS9B LGALS9

7.15e-08492330120235
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9C LGALS9B LGALS9

7.15e-08492321575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9C LGALS9B LGALS9

7.15e-08492318346632
Pubmed

Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.

LGALS9C LGALS9B LGALS9

7.15e-08492311839756
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9C LGALS9B LGALS9

7.15e-08492319670381
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9C LGALS9B LGALS9

7.15e-08492325450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9C LGALS9B LGALS9

7.15e-08492316286920
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9C LGALS9B LGALS9

7.15e-08492334369876
Pubmed

Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.

LGALS9C LGALS9B LGALS9

7.15e-08492333203936
Pubmed

Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.

LGALS9C LGALS9B LGALS9

7.15e-08492322021615
Pubmed

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.

LGALS9C LGALS9B LGALS9

1.78e-07592329242193
Pubmed

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.

LGALS9C LGALS9B LGALS9

1.78e-07592328951537
Pubmed

Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner.

LGALS9C LGALS9B LGALS9

1.78e-07592334847625
Pubmed

Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice.

LGALS9C LGALS9B LGALS9

1.78e-07592322469568
Pubmed

Astrocyte galectin-9 potentiates microglial TNF secretion.

LGALS9C LGALS9B LGALS9

1.78e-07592325158758
Pubmed

C/EBPzeta (CHOP/Gadd153) is a negative regulator of LPS-induced IL-6 expression in B cells.

LGALS9C LGALS9B LGALS9

1.78e-07592319782405
Pubmed

Embryonic implantation in galectin 1/galectin 3 double mutant mice.

LGALS9C LGALS9B LGALS9

1.78e-0759239566950
Pubmed

Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy.

LGALS9C LGALS9B LGALS9

1.78e-07592326278059
Pubmed

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

LGALS9C LGALS9B LGALS9

1.78e-07592337352334
Pubmed

Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model.

LGALS9C LGALS9B LGALS9

1.78e-07592333664349
Pubmed

The glucose transporter 2 regulates CD8+ T cell function via environment sensing.

LGALS9C LGALS9B LGALS9

1.78e-07592337884694
Pubmed

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.

LGALS9C LGALS9B LGALS9

1.78e-07592321385853
Pubmed

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.

LGALS9C LGALS9B LGALS9

3.56e-07692328394331
Pubmed

Tim3 binding to galectin-9 stimulates antimicrobial immunity.

LGALS9C LGALS9B LGALS9

3.56e-07692320937702
Pubmed

Galectins in mouse embryogenesis.

LGALS9C LGALS9B LGALS9

3.56e-0769238674632
Pubmed

Tim-3/galectin-9 regulate the homeostasis of hepatic NKT cells in a murine model of nonalcoholic fatty liver disease.

LGALS9C LGALS9B LGALS9

3.56e-07692323296703
Pubmed

Role of galectin-1 in the developing mouse olfactory system.

LGALS9C LGALS9B LGALS9

6.22e-0779238873770
Pubmed

Mammalian galectins bind galactoseβ1-4fucose disaccharide, a unique structural component of protostomial N-type glycoproteins.

LGALS9C LGALS9B LGALS9

9.94e-07892323751344
Pubmed

Crosstalk between histone modification and DNA methylation orchestrates the epigenetic regulation of the costimulatory factors, Tim‑3 and galectin‑9, in cervical cancer.

LGALS9C LGALS9B LGALS9

9.94e-07892331661141
Pubmed

Mesenchymal stem cells protect against sepsis-associated acute kidney injury by inducing Gal-9/Tim-3 to remodel immune homeostasis.

LGALS9C LGALS9B LGALS9

9.94e-07892336883358
Pubmed

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry.

LGALS9C LGALS9B LGALS9

1.49e-06992321670307
Pubmed

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells.

LGALS9C LGALS9B LGALS9

1.49e-06992325065622
Pubmed

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.

LGALS9C LGALS9B LGALS9

3.87e-061292323817958
GeneFamilyGalectins

LGALS9C LGALS9B LGALS9

2.34e-0515693629
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SELP PAPPA CSMD3 GABBR1

6.59e-05576941179
CoexpressionMIKKELSEN_MCV6_LCP_WITH_H3K4ME3

LGALS9C LGALS9B XDH NYAP1 ARAP1 CRB1 LGALS9

2.74e-06174927MM836
CoexpressionMIKKELSEN_MEF_LCP_WITH_H3K4ME3

LGALS9C LGALS9B XDH NYAP1 ARAP1 LGALS9

1.11e-05142926MM840
CoexpressionNABA_MATRISOME

LGALS9C FGF23 MFAP4 IGFBP6 LGALS9B ZPLD1 ANGPTL4 MUC19 LAMB3 PAPPA USH2A CTSO VWA5B1 LGALS9

1.33e-0510269214M5889
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B PAPPA GRIN2B CADPS2 NYAP1 MOCOS

5.82e-07147916b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNG1 LRFN5 FSTL4 GRIN2B NYAP1 GABBR1

1.84e-06179916a3922476f33d2e4137a12dbda21a1703dff79684
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R3A LGR4 PAPPA SIM1 PTGER3 GLIS1

2.37e-06187916d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 PAPPA SIM1 CADPS2 PTGER3 VWA5B1

2.59e-06190916b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

PPP2R3A FSTL4 SIM1 CADPS2 PTGER3 MOCOS

2.75e-06192916d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MFAP4 TTC28 TSHZ2 HECTD2 LRFN5 CSMD3

2.92e-06194916011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MFAP4 TSHZ2 HECTD2 LRFN5 CADPS2 CSMD3

3.19e-061979160034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NDST1 PPP2R3A TSHZ2 LGR4 XDH PTGER3

3.48e-062009167c2d499af60654b7b28f172ac2c914ad49fb74b4
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SELP MFAP4 PAPPA EFCC1 PTGER3 GLIS1

3.48e-0620091616a3685c41194a0a4a772e4eee372160263480e0
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2B SIM1 CSMD3 USH2A CRB1

1.21e-0514591596712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 GRIN2B USH2A DNAH9 CRB1

1.94e-05160915c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 GRIN2B USH2A DNAH9 CRB1

1.94e-0516091525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GRIN2B SIM1 CSMD3 USH2A DNAH9

2.06e-05162915bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 SIM1 CADPS2 PTGER3 VWA5B1

2.25e-051659159bd332e5ede759a00a47728ea5558c215efdd77a
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL18 TBC1D30 TSHZ2 HECTD2 EFCC1

2.52e-0516991587116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

LIPC TTC28 TSHZ2 KIF26B LRFN5

2.75e-0517291536a96714a0eb6ac438648135336c9791881ddadb
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 GRIN2B CSMD3 USH2A DNAH9

2.98e-05175915887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNG1 FSTL4 GRIN2B NYAP1 GABBR1

3.24e-05178915a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNG1 FSTL4 GRIN2B NYAP1 GABBR1

3.24e-051789151bddbc083c36657bd6910f7466126ab325e88176
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R3A LIPC TSHZ2 KIF26B LRFN5

3.24e-05178915544379f5a6145429762258d426b876bb36c112f5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZPLD1 MUC19 PAPPA CADPS2 PTGER3

3.32e-05179915d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellAT1-AT2_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ZPLD1 ANGPTL4 LAMB3 PAPPA NYAP1

3.41e-051809153c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 PAPPA GRIN2B CADPS2 MOCOS

3.41e-05180915023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

LGR4 SIM1 CSMD3 PTGER3 VWA5B1

3.60e-05182915ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R3A LGR4 SIM1 PTGER3 GLIS1

3.60e-051829159d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 LGR4 SIM1 CADPS2 PTGER3

3.69e-051839152e831a4d99c6f983793df71c0994124c943c6da9
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26B GRIN2B CSMD3 USH2A DNAH9

3.79e-051849152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellwk_08-11-Hematologic-Myeloid-Non-cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LILRA2 HK3 ADGRE3 HLA-DRB5 LGALS9

3.79e-05184915324f91b70913bda3509e234aaf23b46fad91e076
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26B GRIN2B CSMD3 USH2A DNAH9

3.79e-05184915ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26B GRIN2B CSMD3 USH2A DNAH9

3.79e-051849152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLIPR1 TSHZ2 FSTL4 LAMB3 CADPS2

3.89e-05185915a1b2525da018abe458908cab7268bd403ee98d92
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A FSTL4 SIM1 CADPS2 MOCOS

3.99e-0518691508632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-lo_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GLIPR1 HK3 ADGRE3 HLA-DRB5 LGALS9

3.99e-05186915be50f5c7f32b3126442ebff1e7d38aa78b6e4e71
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PPP2R3A TTC28 KIF26B PAPPA GLIS1

3.99e-05186915b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA GRIN2B CADPS2 VWA5B1 MOCOS

4.09e-051879152d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 PAPPA GRIN2B CADPS2 MOCOS

4.09e-05187915e3095455d2f255854f339f6b05fa87852af0700f
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 LILRA2 HK3 HLA-DRB5 LGALS9

4.20e-05188915085b61dfad373e5c39f2496539fbfed1b588115a
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PPP2R3A ZPLD1 PAPPA SIM1 PTGER3

4.20e-051889158f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 PAPPA GRIN2B CADPS2 MOCOS

4.31e-051899153a295c215b5c18e7c673f92b7af5be523421682c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B FSTL4 SIM1 CADPS2 MOCOS

4.31e-051899158ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell368C-Myeloid-Macrophage|368C / Donor, Lineage, Cell class and subclass (all cells)

DNASE2B HK3 HLA-DRB5 ZDHHC19 LGALS9

4.31e-05189915e62355be0d136e2b7c739848022292e9c6af7392
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 SIM1 CADPS2 PTGER3 VWA5B1

4.31e-05189915a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B PAPPA GRIN2B CADPS2 MOCOS

4.31e-05189915c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IGFBP6 ANGPTL4 PAPPA PTGER3 ELOVL2

4.41e-05190915f39ce1678fc375eb2a3af781ddb772b0f12c5744
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF26B FSTL4 SIM1 CADPS2 MOCOS

4.41e-051909154836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MFAP4 HDAC5 TTC28 PTGER3 GLIS1

4.41e-05190915591310e615700321a010a4b90405cbbbbdb3aade
ToppCell390C-Myeloid-Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

DNASE2B HK3 HLA-DRB5 ZDHHC19 LGALS9

4.41e-05190915f933d971f092c4e56e9f670a9205b688c8b1ca28
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFAP4 IGFBP6 LRFN5 ANGPTL4 PAPPA

4.53e-05191915f5ce33af56178333730be308253943c54a0724cf
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 PAPPA SIM1 CADPS2 MOCOS

4.53e-0519191596b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFAP4 IGFBP6 LRFN5 ANGPTL4 PAPPA

4.64e-05192915a8b7c539dc3037071bf068f372e4215563e11de4
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFAP4 IGFBP6 LRFN5 ANGPTL4 PAPPA

4.64e-051929152143e1fad2e88b90d668e12af37b2092d379090f
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MFAP4 IGFBP6 LRFN5 ANGPTL4 PAPPA

4.64e-05192915904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 LILRA2 HK3 ADGRE3 HLA-DRB5

4.76e-05193915c0509798ce06da0ec725c0c7b5cc195455f2c29f
ToppCellPND01|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MFAP4 IGFBP6 ANGPTL4 XDH PAPPA

4.76e-05193915c291345c11cfcbceacbdc001a5851f67478a2779
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

MFAP4 IGFBP6 TSHZ2 LGR4 PAPPA

4.87e-05194915d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

IGFBP6 TTC28 TSHZ2 ANGPTL4 CRY1

4.99e-05195915ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 MFAP4 TSHZ2 KIF26B PTGER3

5.12e-05196915fd0a2b863dedaf08d18e7f67da18ac7e853991e4
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HK3 ADGRE3 HLA-DRB5 PTGER3 LGALS9

5.12e-051969152793ad692d49b3ee78a5cd2d8e0220bf5188a686
ToppCellRA-02._Fibroblast_II|World / Chamber and Cluster_Paper

IGFBP6 TSHZ2 LRFN5 LGR4 PAPPA

5.12e-05196915e8cbda03837f1f26470a9d93aa7fdaa04e08e38a
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 MFAP4 TSHZ2 KIF26B PTGER3

5.24e-05197915c7b33d64e5cba3a8fc6f2d6aa85ebc83893195de
ToppCelldistal-mesenchymal-Adventitial_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MFAP4 IGFBP6 TSHZ2 LRFN5 PAPPA

5.37e-05198915bfd720e2dae3b6b3dc2bf8b2096c554fd456e756
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LGALS9C EGR2 HLA-DRB5 TRIM38 LGALS9

5.37e-05198915cc808d872d2404a79ec119bb0be62688a30c93a7
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

KDM5B MFAP4 TSHZ2 KIF26B LRFN5

5.50e-051999155b9d355795dd03a22f0961dfd143425c367a4654
ToppCellmLN-Dendritic_cell-cDC2|mLN / Region, Cell class and subclass

PPP2R3A IGFBP6 ADGRE3 LAMB3 LGALS9

5.50e-05199915cb17bccb47d04f7793709f9a4376fcc8ce95430c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 MFAP4 TSHZ2 KIF26B PTGER3

5.50e-05199915bb201deb281619113edcd1de2af2d3eb21b967b8
ToppCellmLN-(5)_Dendritic_cell-(50)_cDC2|mLN / shred on region, Cell_type, and subtype

PPP2R3A IGFBP6 ADGRE3 LAMB3 LGALS9

5.50e-051999158d1b18596a0965427abefe0be744c74e4c11d5d3
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 LILRA2 HK3 ADGRE3 LGALS9

5.50e-051999150a9783808528bc4c6d797d849a9177330c8fb867
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGEF40 LIPC KIF26B PAPPA CRB1

5.63e-05200915858421b91f5207b7934b5c219752cb9322a3da31
ToppCell390C-Fibroblasts-Fibroblast-H-|390C / Donor, Lineage, Cell class and subclass (all cells)

MFAP4 IGFBP6 TSHZ2 ANGPTL4 PAPPA

5.63e-05200915ec7d6a08e34bcad5b3bbff56ebef96ae17e4cefd
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-4|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MFAP4 IGFBP6 TSHZ2 ANGPTL4 PAPPA

5.63e-052009157642a14855589b0b3f68dbdc9e4d3fc7291854f7
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MFAP4 PAPPA EFCC1 PTGER3 GLIS1

5.63e-052009158ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellmild-Non-classical_Monocyte|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LILRA2 HK3 IGFBP6 HLA-DRB5 ARAP1

5.63e-05200915692b48da9fd56bafcb3c8b33b0fe369160881c45
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

FAT2 IGFBP6 FSTL4 LAMB3 FAF1

5.63e-052009155cea84581201cee7ba8141b96e65864f4fd67113
ToppCellmild-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LILRA2 HK3 HLA-DRB5 ARAP1 LGALS9

5.63e-05200915334bab6bf93d455f3526e817ea5785d8b6ee531c
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGEF40 LIPC KIF26B PAPPA CRB1

5.63e-05200915a7022762c1d8aedb7b3e9605873b1e68b9907b35
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MFAP4 IGFBP6 TSHZ2 ANGPTL4 PAPPA

5.63e-05200915444c72334df421375ae6fc69b0adfd4950d49a43
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-4|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MFAP4 IGFBP6 TSHZ2 ANGPTL4 PAPPA

5.63e-052009155826c17da67bdaba3a828792279004218d8260c8
ToppCellBiopsy_Other_PF-Epithelial-Basal|Biopsy_Other_PF / Sample group, Lineage and Cell type

FAT2 IGFBP6 FSTL4 LGR4 LAMB3

5.63e-052009157098ae4b0ea8ba607519eaed8577c577530fc2a1
ToppCell390C-Fibroblasts-Fibroblast-H|390C / Donor, Lineage, Cell class and subclass (all cells)

MFAP4 IGFBP6 TSHZ2 ANGPTL4 PAPPA

5.63e-05200915671e731977c58a0c44c36b56422085d93d999aad
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MFAP4 LRFN5 PAPPA PTGER3 GLIS1

5.63e-05200915fb53be20392a8309a7393774c774a1b1aec6e676
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-B3GAT2--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

ARHGEF40 LIPC KIF26B PAPPA CRB1

5.63e-052009152131c8e7fa054b79906eaf60536da892438b09cd
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Pvalb_(Layer_5a)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DNASE2B ADGRE3 LAMB3

1.55e-045191328d6b12c44ad308560931d275e0dd0243a555bf3
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CACNG1 FAT2 LRFN5 LGR4

1.74e-0413691427a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNG1 FAT2 LRFN5 LGR4

1.74e-0413691488b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIPC ANGPTL4 LGR4 ELOVL2

1.89e-0413991482bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIPC ANGPTL4 LGR4 ELOVL2

1.89e-04139914fc9ac09c2106e88104a52575832d71d17765eec8
ToppCellfacs-Liver-Hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIPC ANGPTL4 LGR4 ELOVL2

1.89e-04139914fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIPC ANGPTL4 LGR4 ELOVL2

1.89e-041399144ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

DNASE2B PPP2R3A DNAH9 CRY1

2.00e-04141914399380de5ea09e22fd128e3e55fffeffc4874c15
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Slc17a8|Hippocampus / BrainAtlas - Mouse McCarroll V32

FGF23 CACNG1 PAPPA

2.52e-046091340f29dfdbb17d39d8e6bb69dc5066fca3cd03308
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Slc17a8-Inhibitory_Neuron.Gad1Gad2Slc17a8_Sst.Ncam2_(Interneuron,__GABA/Glutamate_co-releasing?)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

FGF23 CACNG1 PAPPA

2.52e-04609133a58f7a8e3d8a544286b7a3fe62efac8a0a0bb11
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Slc17a8-Inhibitory_Neuron.Gad1Gad2Slc17a8_Sst.Ncam2_(Interneuron,__GABA/Glutamate_co-releasing?)|Hippocampus / BrainAtlas - Mouse McCarroll V32

FGF23 CACNG1 PAPPA

2.52e-0460913ce13bbda7d105e1cb421790fb50d3b55ba2ed09a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SIM1 CADPS2 PTGER3 VWA5B1

2.53e-0415091487968ce885a4959616f0321f58517fe8029ba1b1
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDST1 IGFBP6 HECTD2 CADPS2

2.66e-0415291482a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 LGR4 SIM1 PTGER3

2.94e-041569144d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBXL18 EGR2 TSHZ2 LCMT2

3.01e-04157914beab0ac47202266b04543c02cfcdda012375e879
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GLIPR1 LILRA2 ARHGEF40 KIF26B

3.31e-041619143a5f2877e3b29463a3a6da05009b0ab8747b4c47
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FSTL4 PAPPA CADPS2 MOCOS

3.39e-04162914285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L5_RORB_SNHG7|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LGALS9B TSHZ2 FSTL4 CADPS2

3.39e-04162914daacccf8b1374680803f49135673a00e09691cde
ToppCelldroplet-Lung-nan-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND5B LIPC LAMB3 SHQ1

3.47e-041639145efecdd8a069a822bc9d35b407092925a865e629
DiseaseHereditary xanthinuria

XDH MOCOS

8.59e-062872cv:C5779508
DiseaseAutistic Disorder

KDM5B EGR2 XDH GRIN2B CADPS2 CSMD3 GABBR1

1.25e-05261877C0004352
Diseaserenal cell carcinoma

SLC6A18 FAF1 CRY1

2.62e-0442873EFO_0000681
Diseaseblood nickel measurement

SELP FAT2 TSHZ2 USH2A

4.46e-04120874EFO_0007583
Diseaseurate measurement, bone density

GLIPR1 TTC28 TSHZ2 ADGRE3 SIM1 CADPS2 USH2A DNAH9

4.89e-04619878EFO_0003923, EFO_0004531
Diseasecholesteryl ester 24:5 measurement

IGFBP6 ELOVL2

5.56e-0412872EFO_0021448
Diseasetriglycerides in LDL measurement

SPHK2 LIPC ANGPTL4

6.13e-0456873EFO_0022320
Diseasethalamus volume change measurement

KIF26B LRFN5

7.64e-0414872EFO_0021496
Diseasetriglycerides in medium LDL measurement

SPHK2 LIPC ANGPTL4

8.26e-0462873EFO_0022322
DiseaseAllergic Reaction

SELP HLA-DRB4 HLA-DRB5

8.65e-0463873C1527304
Diseasepancreas fat measurement

GSX1 FAF1

8.80e-0415872EFO_0600049
DiseaseHypersensitivity

SELP HLA-DRB4 HLA-DRB5

9.06e-0464873C0020517
Diseasebody mass index, type 2 diabetes mellitus

FAF1 ARAP1

1.00e-0316872EFO_0004340, MONDO_0005148
Diseaseautism spectrum disorder (implicated_via_orthology)

NDST1 KDM5B CADPS2 MOCOS

1.08e-03152874DOID:0060041 (implicated_via_orthology)
Diseasemetabolite measurement, diet measurement

GSX1 LIPC GABBR1

1.22e-0371873EFO_0004725, EFO_0008111
Diseasetestosterone measurement

ARHGEF40 TTC28 EGR2 TSHZ2 LAMB3 XDH CSMD3 USH2A TRIM38 FAF1 ARAP1

1.30e-0312758711EFO_0004908
Diseasepentachlorophenol measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022071
Diseaseparathion measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022070
Diseasepotassium chromate measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022072
Diseasemercuric chloride measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022068
Diseaseheptachlor epoxide measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022067
Diseasemethoxychlor measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022069
Disease4,6-dinitro-o-cresol measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022053
Disease2,4,5-trichlorophenol measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022052
Diseaseazinphos methyl measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022055
Diseasealdrin measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022054
Diseasedicofol measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022060
Diseasedisulfoton measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022062
Diseasedieldrin measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022061
Diseaseendrin measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022064
Diseaseendosulfan measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022063
Diseaseheptachlor measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022066
Diseaseethion measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022065
Diseasechlorpyrifos measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022057
Diseasecadmium chloride measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022056
Diseasediazinon measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022059
Diseasedibutyl phthalate measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0022058
Diseaseenvironmental exposure measurement

SELP TSHZ2 USH2A

1.33e-0373873EFO_0008360
DiseaseRetinitis pigmentosa

KLHL7 USH2A CRB1

1.38e-0374873cv:C0035334
DiseaseDDT metabolite measurement

SELP TSHZ2 USH2A

1.38e-0374873EFO_0007886
Diseaseaspartate aminotransferase measurement

CACNG1 LIPC TTC28 ZPLD1 FSTL4 MUC19 XDH GABBR1 MOCOS

1.39e-03904879EFO_0004736
Diseaselevel of Sphingomyelin (d38:2) in blood serum

LIPC ANGPTL4

1.42e-0319872OBA_2045179
Diseasediacylglycerol 38:5 measurement

LIPC ELOVL2

1.42e-0319872EFO_0020067
Diseasealpha-tocopherol measurement

MRPL46 USH2A

1.58e-0320872EFO_0007898
Diseaseadvanced glycosylation end product-specific receptor ligand measurement

HLA-DRB5 TRIM38

1.74e-0321872EFO_0010762
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

TSHZ2 KIF26B CSMD3

2.27e-0388873EFO_0803332
DiseaseSjogren's syndrome (is_marker_for)

SELP MUC19

2.27e-0324872DOID:12894 (is_marker_for)
Diseaseretinitis pigmentosa (implicated_via_orthology)

USH2A CRB1

2.88e-0327872DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GYDTPLHFACKFGNA

ANKLE2

411

Q86XL3
GACFLRHGDQFSLYA

ARHGEF40

1156

Q8TER5
FGTCSHSNLNGQYFR

ANGPTL4

351

Q9BY76
GFNITYNTFGHNECP

CSMD3

821

Q7Z407
RCYFPSFLGGNRSQF

ACER1

106

Q8TDN7
SSRNYFGAQPHYRLC

CEP57

271

Q86XR8
CQSGFAYHLFPRSRL

DHX30

786

Q7L2E3
TFRQFHARLCGYFGT

EFCC1

141

Q9HA90
GEKNCSYFRHFNPGE

CACNG1

76

Q06432
YPGFFPSQCQRDLHG

EGR2

226

P11161
FGHPYRGASQFLASA

IRX6

6

P78412
SPSHGGQYRCYSAHN

LILRA2

286

Q8N149
STFALSFGGNPLHCN

LRFN5

231

Q96NI6
GFDALSNGAHFICNY

GLIPR1

161

P48060
HNLLVCSVNGFYPGS

HLA-DRB5

141

Q30154
VPCGHSYFGATLNSF

ELOVL5

161

Q9NYP7
GYHIGRNQFPFVCQA

GABBR1

651

Q9UBS5
HFNPRFEDGGYVVCN

LGALS9C

61

Q6DKI2
PCATSNYTGFANKHG

KIF26B

251

Q2KJY2
HFNPRFEDGGYVVCN

LGALS9B

61

Q3B8N2
HFNPRFEDGGYVVCN

LGALS9

61

O00182
GNSHRFSFCQYPFVI

HECTD2

361

Q5U5R9
CNNHAPLFNRSSYDG

FAT2

451

Q9NYQ8
TFDGVKYNFPGNCHF

MUC19

826

Q7Z5P9
GYGGDAPFCTRLNHS

PTGER3

6

P43115
THGGNYRCFGSFRAL

KIR3DL3

286

Q8N743
FGSQYCHAPLGRQHS

GSX1

86

Q9H4S2
RAHIPNFTFNLGYSG

NDST1

346

P52848
NGGSFQPGCHFLELY

LIPC

246

P11150
SYNNIRDLPSFNGCH

LGR4

351

Q9BXB1
AGCFPLFHRGEYSAS

LGR4

676

Q9BXB1
HLFCYPAQSNFSGVR

MOCOS

196

Q96EN8
ALFGGSQPQSCRYFN

KLHL7

296

Q8IXQ5
TFPRAYHSGFNQGFN

KDM5B

581

Q9UGL1
GPGNDTCGFHSFFNT

PAPPA

616

Q13219
LQLGFSFSFPCHQTG

HK3

161

P52790
LCGHYNNDGNAPSFG

PPP2R3A

161

Q06190
LPYRGSNSIAHFFCE

OR2D2

166

Q9H210
PILNGGAAFHCARTY

PATZ1

531

Q9HBE1
RPDGNCFYRAFGFSH

OTUB1

86

Q96FW1
NRSPHQAFRSGGFIC

DNASE2B

326

Q8WZ79
CGQSFFGPTLNSFIH

ELOVL2

166

Q9NXB9
NIFGSHYFDPENCRF

FGF23

101

Q9GZV9
HLGGYFFIQCRQDSP

FSTL4

651

Q6MZW2
FQQFFHCYCPVGFGR

CRY1

406

Q16526
NPRHYGQSGFFASLC

DNAJC6

416

O75061
GSGSSPAACRFAHYF

DENND5B

11

Q6ZUT9
ENQISHFRYCFPFGR

CADPS2

756

Q86UW7
HNLLVCSVNGFYPGS

HLA-DRB4

141

P13762
EARVNCSHPFGAFRY

SELP

456

P16109
RHHPGTFGFNTTCYF

SELP

656

P16109
RFGPFHSNNEIYCNR

KLHDC3

201

Q9BQ90
GFTGLTYANPQGCHR

LAMB3

416

Q13751
GFQSLDCGSSFYHPT

KRTAP15-1

111

Q3LI76
QSPNLYCHFANGIGE

DNAH9

2751

Q9NYC9
FSSRYGDCHPVFFIG

FAF1

341

Q9UNN5
SLHRYDNGNFFPGSG

HDAC5

891

Q9UQL6
PQGYQGSFHSIQSCF

GLIS1

511

Q8NBF1
CHCPFDNLSRTFYGG

CRB1

421

P82279
GAQTLYVPNCDHRGF

IGFBP6

181

P24592
TFPACHRNGDFTGGY

NYAP1

711

Q6ZVC0
NCTRFHPNSNYVATG

TAF5

631

Q15542
KDHYFGFDPQTGRCQ

USH2A

986

O75445
RFIGNGYCKFPSSTH

USH2A

1521

O75445
GNAPCGHYTFKFPQA

MRPL46

206

Q9H2W6
YNGNTGCHIFTFPKA

TRIM38

426

O00635
NFFRYHGLSSLCNLG

TMEM205

156

Q6UW68
PFYFSFSRCTLSGGH

FBXL18

316

Q96ME1
SCHFANLNGFYLGGS

MFAP4

211

P55083
PGSQHDASCAYRQFS

SIM1

426

P81133
ALNPQCHYGFGNLRS

SHQ1

141

Q6PI26
GHIAFASYNSPRNDC

SLC6A18

271

Q96N87
CVPGYRLHSGNEQFS

ADGRE3

96

Q9BY15
PFKAQNGLCHYFSGS

CTSO

196

P43234
SGGFHDRYFILNSSC

ARAP1

1296

Q96P48
FNGYNCDANLHSRFP

ZPLD1

21

Q8TCW7
YSCSAVPHQGRGFSQ

MIOS

746

Q9NXC5
SHFSLGCPQLGYAAA

SPHK2

591

Q9NRA0
PQHTYFINCGDSRGL

PPM1A

136

P35813
ACGFGPSFFLSHQTA

TONSL

1166

Q96HA7
YNAGNICNHFFTRGF

UAP1L1

326

Q3KQV9
NSGNPFHYFSYGVAC

XDH

1146

P47989
PGAINSCRSEYHAAF

TBC1D30

611

Q9Y2I9
KGCFSYQNSPGSHLS

TSHZ2

61

Q9NRE2
VHRGGYNGFNQCLPA

ZNF43

126

P17038
AFFYHSNCKEPGIAG

THYN1

111

Q9P016
GNFHCSRGEYVQAAP

TTC28

601

Q96AY4
CGKAFYSPSSFQRHE

ZNF491

276

Q8N8L2
RHLQGYNPFDQGCAS

ZDHHC19

231

Q8WVZ1
NSPRGYFHTFAGDTC

WASL

101

O00401
GNCFSFGTYFNPHTV

LCMT2

661

O60294
ATNRFRFHFQGPCGT

SIRT5

281

Q9NXA8
HAFSTRCYSFGIGPN

VWA5B1

481

Q5TIE3
RHNYRTCFPQYLNGG

TTLL13

351

A6NNM8
GGNFCRSCPSKLHNY

GRIN2B

1211

Q13224