Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

HTR2B RGS22 PKD1L2

3.07e-0443613GO:0001965
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM1 GRM4

3.26e-049612GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM1 GRM4

3.26e-049612GO:0001640
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1E

3.26e-049612GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1E

3.26e-049612GO:0099626
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A CACNA1E PKD2L1 PKD1L2

6.53e-04129614GO:0005262
GeneOntologyMolecularFunctionSNARE binding

CACNA1A NBAS MYO5A SNAP91

7.95e-04136614GO:0000149
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1E

8.16e-0414612GO:0008331
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1E PKD2L1 PKD1L2

1.17e-03151614GO:0015085
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNHD1 DNAH11

1.36e-0318612GO:0008569
GeneOntologyBiologicalProcessresponse to pain

CACNA1A CACNA1E RELN EDNRB

1.46e-0551604GO:0048265
GeneOntologyBiologicalProcesslocomotory behavior

CACNA1A CACNA1E RELN DSCAM MYO5A GRM1 ANKFN1

1.80e-05284607GO:0007626
GeneOntologyBiologicalProcessmulticellular organismal response to stress

CACNA1A CACNA1E RELN ANKFN1 EDNRB

3.28e-05126605GO:0033555
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

CACNA1A RELN MYO5A GRM1 GRM4

4.10e-05132605GO:0035249
GeneOntologyBiologicalProcessbehavior

CACNA1A CACNA1E RELN HTR2B DSCAM MYO5A GRM1 GRM4 ANKFN1 EDNRB DNAH11

4.52e-058916011GO:0007610
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1A CACNA1E HTR2B MYO5A PKD2L1 PKD1L2 EDNRB

1.38e-04392607GO:0070588
GeneOntologyBiologicalProcessregulation of synaptic transmission, glutamatergic

RELN MYO5A GRM1 GRM4

1.49e-0492604GO:0051966
MousePhenoimpaired balance

CACNA1A RELN DSCAM MYO5A AK9 GRM1

3.83e-06121496MP:0001525
MousePhenolethality at weaning

CACNA1A RELN MYO5A SNAP91 EDNRB

1.08e-0584495MP:0008569
MousePhenoabnormal melanocyte proliferation

GRM1 EDNRB

1.20e-052492MP:0010741
MousePhenoabsent distal visceral endoderm

BPTF INO80

1.20e-052492MP:0012161
MousePhenolethality at weaning, complete penetrance

CACNA1A RELN MYO5A EDNRB

1.95e-0546494MP:0011083
MousePhenomuscle spasm

CACNA1A RELN MYO5A GRM1

5.62e-0560494MP:0000743
MousePhenoabnormal righting response

CACNA1A RELN MYO5A GRM1 FAAH VEGFB

5.79e-05195496MP:0002862
MousePhenoabnormal distal visceral endoderm morphology

BPTF INO80

7.19e-054492MP:0010126
MousePhenoabnormal postural reflex

CACNA1A RELN MYO5A GRM1 FAAH VEGFB

7.24e-05203496MP:0002980
MousePhenomuscle twitch

CACNA1A RELN MYO5A GRM1

7.25e-0564494MP:0009046
MousePhenoabsent anterior visceral endoderm

BPTF INO80

2.50e-047492MP:0012159
DomainPKD_2

PKD2L1 PKD1L2

1.04e-045612IPR003915
DomainVDCC_a1su_IQ

CACNA1A CACNA1E

2.18e-047612IPR014873
DomainGPHH

CACNA1A CACNA1E

2.18e-047612PF16905
DomainGPHH_dom

CACNA1A CACNA1E

2.18e-047612IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1E

2.18e-047612SM01062
DomainCa_chan_IQ

CACNA1A CACNA1E

2.18e-047612PF08763
DomainGPCR_3_mtglu_rcpt

GRM1 GRM4

2.90e-048612IPR000162
DomainVDCCAlpha1

CACNA1A CACNA1E

4.64e-0410612IPR002077
DomainPKD_channel

PKD2L1 PKD1L2

5.66e-0411612PF08016
DomainPKD1_2_channel

PKD2L1 PKD1L2

5.66e-0411612IPR013122
DomainNCD3G

GRM1 GRM4

8.00e-0413612PF07562
DomainGPCR_3_9-Cys_dom

GRM1 GRM4

8.00e-0413612IPR011500
DomainDynein_HC_stalk

DNHD1 DNAH11

9.31e-0414612IPR024743
DomainDynein_heavy_dom-2

DNHD1 DNAH11

9.31e-0414612IPR013602
DomainDHC_N2

DNHD1 DNAH11

9.31e-0414612PF08393
DomainMT

DNHD1 DNAH11

9.31e-0414612PF12777
DomainATPase_dyneun-rel_AAA

VWA8 DNAH11

9.31e-0414612IPR011704
DomainGPCR_3_CS

GRM1 GRM4

9.31e-0414612IPR017979
DomainAAA_5

VWA8 DNAH11

9.31e-0414612PF07728
DomainDHC_fam

DNHD1 DNAH11

1.07e-0315612IPR026983
DomainDynein_heavy_dom

DNHD1 DNAH11

1.07e-0315612IPR004273
DomainDynein_heavy

DNHD1 DNAH11

1.07e-0315612PF03028
DomainGPCR_3

GRM1 GRM4

2.12e-0321612IPR000337
Domain7tm_3

GRM1 GRM4

2.32e-0322612PF00003
DomainG_PROTEIN_RECEP_F3_2

GRM1 GRM4

2.32e-0322612PS00980
DomainG_PROTEIN_RECEP_F3_3

GRM1 GRM4

2.32e-0322612PS00981
DomainG_PROTEIN_RECEP_F3_1

GRM1 GRM4

2.32e-0322612PS00979
DomainG_PROTEIN_RECEP_F3_4

GRM1 GRM4

2.32e-0322612PS50259
DomainGPCR_3_C

GRM1 GRM4

2.32e-0322612IPR017978
DomainIQ

XKR7 MYO5A ASPM

2.36e-0381613SM00015
DomainIQ_motif_EF-hand-BS

XKR7 MYO5A ASPM

3.18e-0390613IPR000048
DomainGPS

ADGRF3 PKD1L2

5.50e-0334612SM00303
DomainGPS

ADGRF3 PKD1L2

5.83e-0335612PF01825
DomainP-loop_NTPase

DNHD1 TRANK1 MYO5A VWA8 ASPM AK9 INO80 DNAH11

6.11e-03848618IPR027417
DomainGPS

ADGRF3 PKD1L2

6.15e-0336612PS50221
DomainGPS

ADGRF3 PKD1L2

6.49e-0337612IPR000203
DomainANF_lig-bd_rcpt

GRM1 GRM4

6.49e-0337612IPR001828
DomainANF_receptor

GRM1 GRM4

6.49e-0337612PF01094
DomainPeripla_BP_I

GRM1 GRM4

7.19e-0339612IPR028082
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1E HTR2B GRM1 EDNRB

1.77e-04178425M2890
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

HTR2B GRM1 EDNRB

4.37e-0450423M47951
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1E

4.69e-0411422M47958
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

4.69e-0411422MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1E

4.69e-0411422M26913
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A CACNA1E MIA3 DSCAM MYO5A SNAP91 WDR7 KDM5A GRM1 GRM4 ITIH4

1.15e-06963631128671696
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

CACNA1A RELN GRM1 GRM4

1.38e-064563425979088
Pubmed

Rolling Nagoya mouse strain (PROD-rol/rol) with classic piebald mutation.

CACNA1A EDNRB

3.23e-06263224758835
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

3.23e-06263216381801
Pubmed

Neutrophil-derived glutamate regulates vascular endothelial barrier function.

GRM1 GRM4

3.23e-06263211847215
Pubmed

BPTF promotes hepatocellular carcinoma growth by modulating hTERT signaling and cancer stem cell traits.

BPTF TERT

3.23e-06263230419422
Pubmed

Functional role of mGluR1 and mGluR4 in pilocarpine-induced temporal lobe epilepsy.

GRM1 GRM4

3.23e-06263217446080
Pubmed

Effects of thyrotropin releasing hormone on cerebellar mutant mice--a kinesiological comparison between rolling mouse Nagoya, weaver and reeler.

CACNA1A RELN

9.68e-0636326811784
Pubmed

Abnormal expression of tyrosine hydroxylase immunoreactivity in cerebellar cortex of ataxic mutant mice.

CACNA1A MYO5A

9.68e-06363210350535
Pubmed

Mouse telomerase reverse transcriptase (mTert) expression marks slowly cycling intestinal stem cells.

LGR5 TERT

9.68e-06363221173232
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1E

9.68e-06363238996073
Pubmed

Telomere dysfunction activates YAP1 to drive tissue inflammation.

LGR5 TERT

9.68e-06363232958778
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1E

9.68e-06363224523520
Pubmed

Direct recording and molecular identification of the calcium channel of primary cilia.

PKD2L1 PKD1L2

9.68e-06363224336289
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

RELN HTR2B SNAP91 ASTN2 GRM4 FAAH

1.76e-0530063619086053
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1E

1.93e-05463232616470
Pubmed

Central noradrenaline metabolism in cerebellar ataxic mice.

CACNA1A RELN

1.93e-0546326123371
Pubmed

Bleomycin, unlike other male-mouse mutagens, is most effective in spermatogonia, inducing primarily deletions.

MYO5A EDNRB

1.93e-05463210946246
Pubmed

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.

BPTF TERT

1.93e-05463222797724
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1E

1.93e-05463237141091
Pubmed

Interactions of Rabconnectin-3 with Cav2 calcium channels.

CACNA1A WDR7

1.93e-05463231253182
Pubmed

Chromatin remodeling: recruitment of histone demethylase RBP2 by Mad1 for transcriptional repression of a Myc target gene, telomerase reverse transcriptase.

KDM5A TERT

1.93e-05463219762557
Pubmed

Functional coupling between mGluR1 and Cav3.1 T-type calcium channels contributes to parallel fiber-induced fast calcium signaling within Purkinje cell dendritic spines.

CACNA1E GRM1

1.93e-05463219657020
Pubmed

Inheritance in the House Mouse, the Linkage Relations of Short-Ear, Hairless, and Naked.

MYO5A EDNRB

1.93e-05463217246610
Pubmed

5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.

HTR2B MYO5A

3.22e-0556329165122
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1E

3.22e-0556328825650
Pubmed

Candidate genes required for embryonic development: a comparative analysis of distal mouse chromosome 14 and human chromosome 13q22.

LMO7 EDNRB

3.22e-05563211829485
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1E

3.22e-05563215451373
Pubmed

Slate--a new coat color mutant in the mouse.

MYO5A EDNRB

3.22e-05563213943454
Pubmed

Mechanisms of mutation induction in germ cells of the mouse as assessed by the specific locus test.

MYO5A EDNRB

3.22e-05563210517996
Pubmed

Umami taste in mice uses multiple receptors and transduction pathways.

GRM1 GRM4

3.22e-05563222183726
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1E

3.22e-05563211296258
Pubmed

Requirement for early-generated neurons recognized by monoclonal antibody lot1 in the formation of lateral olfactory tract.

RELN GRM1

3.22e-0556329742149
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1E

4.82e-05663235324301
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

CACNA1A CACNA1E

4.82e-05663212827191
Pubmed

Melphalan, a second chemical for which specific-locus mutation induction in the mouse is maximum in early spermatids.

MYO5A EDNRB

4.82e-0566321378547
Pubmed

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

CACNA1A CACNA1E

4.82e-0566329238069
Pubmed

LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.

BPTF LGR5

4.82e-05663230224759
Pubmed

Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.

GRM1 GRM4

4.82e-0566328824806
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

BPTF RELN MIA3 LMO7 MMRN2 ACAP2

4.88e-0536063633111431
Pubmed

Transcriptional profiling of Wnt4 mutant mouse kidneys identifies genes expressed during nephron formation.

HNF1B MAPK12 SNAP91

4.94e-053963318346943
Pubmed

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

RELN HTR2B GRM1 GRM4

6.43e-0511863419156168
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A CACNA1E

6.74e-05763235176221
Pubmed

Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.

GRM1 GRM4

6.74e-0576329920659
Pubmed

A chemically-induced variegated-type position effect in the mouse.

MYO5A EDNRB

6.74e-05763213877379
Pubmed

Genetic correction of PSA values using sequence variants associated with PSA levels.

HNF1B TERT

6.74e-05763221160077
Pubmed

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

BPTF TERT

8.98e-05863223143601
Pubmed

Behavioral effects of neonatal lesions on the cerebellar system.

CACNA1A MYO5A

8.98e-05863225907855
Pubmed

Biochemical and recessive visible specific locus responses of C3H/HeH to fractionated, acute radiation.

MYO5A EDNRB

8.98e-05863212644183
Pubmed

The Effects of Genotype and Cell Environment on Melanoblast Differentiation in the House Mouse.

MYO5A EDNRB

1.15e-04963217247639
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1E

1.15e-04963216382099
Pubmed

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

GRM1 GRM4

1.44e-04106329069281
Pubmed

The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.

GRM1 GRM4

1.44e-041063217156446
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

PKD2L1 PKD1L2

1.44e-041063216805797
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

BPTF KDM5A SMARCD3 INO80

1.93e-0415763430186101
Pubmed

Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch.

LGR5 TERT

2.11e-041263225480918
Pubmed

Identification of epilepsy genes in human and mouse.

CACNA1A MYO5A

2.11e-041263211700294
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRM1 GRM4

2.49e-041363220859245
Pubmed

Pigmentation-related genes and their implication in malignant melanoma susceptibility.

MYO5A EDNRB

2.90e-041463219320733
Pubmed

Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function.

HNF1B LGR5

2.90e-041463219833888
Pubmed

Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma.

RGS22 TERT

2.90e-041463224403052
Pubmed

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses.

GRM1 GRM4

2.90e-041463221795692
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1A CACNA1E

3.34e-041563220188150
Pubmed

Interaction of the murine dilute suppressor gene (dsu) with fourteen coat color mutations.

MYO5A EDNRB

3.34e-04156322379821
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1A CACNA1E

3.34e-041563224453333
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A CACNA1E MYO5A SNAP91 WDR7

4.20e-0434763517114649
Pubmed

Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly.

RELN ASPM

4.85e-041863228272472
Pubmed

Genome-wide association of mood-incongruent psychotic bipolar disorder.

TRANK1 SNAP91

4.85e-041863223092984
Pubmed

Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche.

LGR5 TERT

4.85e-041863226015543
Pubmed

Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.

BPTF MAPK12 GRM4

5.03e-048563325131634
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SNAP91 XPO6 PHLPP1

5.39e-048763312465718
Pubmed

Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.

PGAM2 EDNRB

5.41e-041963231847788
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

RELN GRM1

6.01e-042063229961574
Pubmed

Neurog1 and Neurog2 control two waves of neuronal differentiation in the piriform cortex.

RELN GRM1

6.01e-042063224403153
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

HNF1B DNAH11

6.01e-042063217251353
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

MAPK12 VWA8 LMO7 PHLPP1 ACAP2

6.19e-0437863534315543
Pubmed

Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.

DSCAM VWA8

6.63e-042163224057671
Pubmed

Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

RELN DSCAM

7.29e-042263222726835
Pubmed

Circular RNA profile in liver tissue of EpCAM knockout mice.

HNF1B LGR5

7.29e-042263231524221
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

CACNA1A CACNA1E HSPA12B DNAH11

8.58e-0423363437704626
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRM1 GRM4

8.69e-042463235746896
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 MYO5A ASPM TERT

8.72e-0423463436243803
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

BPTF VWA8 KDM5A ASPM SMARCD3 INO80 RALGAPA2 ITIH4

8.89e-04111663831753913
Pubmed

A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

RPUSD4 ARMCX5 TERT

9.31e-0410563323284306
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

VWA8 WDR7 PHLPP1

9.31e-041056339628581
Pubmed

Impact of single nucleotide polymorphisms and of clinical risk factors on new‐onset diabetes mellitus in HIV‐infected individuals.

HNF1B LGR5

9.43e-042563220879858
Pubmed

Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.

HNF1B LGR5

1.02e-032663228193997
Pubmed

Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells.

RELN GRM1

1.18e-032863227178193
Pubmed

The DNA sequence of human chromosome 7.

RELN RHBDD2 SMARCD3 TYW1 DNAH11

1.23e-0344163512853948
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

RELN ASPM

1.36e-033063219054571
Pubmed

Repurposing of the multiciliation gene regulatory network in fate specification of Cajal-Retzius neurons.

RELN GRM1

1.36e-033063237321213
Pubmed

Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models.

GCNT3 MYO5A

1.45e-033163230642949
Pubmed

Corticothalamic Projection Neuron Development beyond Subtype Specification: Fog2 and Intersectional Controls Regulate Intraclass Neuronal Diversity.

CACNA1E SMARCD3

1.45e-033163227321927
Pubmed

The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord.

PKD2L1 PKD1L2

1.45e-033163226839365
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

PKD2L1 PKD1L2

1.64e-033363219834762
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

CACNA1E MYO5A WDR7 GRM1

1.71e-0328163428706196
Pubmed

Genetical genomic determinants of alcohol consumption in rats and humans.

HTR2B GRM1 FAAH

1.72e-0313063319874574
Pubmed

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

HNF1B LGR5

1.75e-033463220581827
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM1 GRM4

1.76e-048462281
CoexpressionMORI_PLASMA_CELL_UP

NBAS CD28 SGPP2 PGAM2

8.21e-0654624MM597
CoexpressionMORI_PLASMA_CELL_UP

NBAS CD28 SGPP2 PGAM2

8.21e-0654624M1487
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CACNA1A CACNA1E HNF1B RELN MIA3 DSCAM MYO5A SNAP91 ANO5 GRM1 GRM4 LGR5

9.21e-0611066212M39071
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TRANK1 RGS22 ANO5 PKD1L2 GRM1 DNAH11

7.78e-091846372cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TRANK1 RGS22 ANO5 PKD1L2 GRM1 DNAH11

7.78e-09184637ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN TRANK1 RGS22 ANO5 PKD1L2 GRM1 DNAH11

7.78e-091846372b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A RELN SNAP91 ASTN2 GRM4 DNAH11

2.65e-071876361b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A RELN XKR7 DSCAM GRM1

2.03e-06146635c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN HTR2B MMRN2 HSPA12B EDNRB

2.32e-0615063596b160f163030fbf48aedc37d6ae224e11492c52
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A HNF1B PHLPP1 PGAM2 FAAH

3.59e-06164635d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RELN HTR2B MMRN2 LGR5

6.45e-061856353a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCelldroplet-Bladder-nan-24m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RELN HTR2B MMRN2 PIWIL2

6.45e-0618563590caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RELN HTR2B MMRN2 LGR5

6.45e-06185635224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1A SNAP91 SGPP2 PKD2L1 PGAM2

6.62e-06186635c7983281a290201567b398e9ea6baddb96c692bb
ToppCelldroplet-Lung-21m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HTR2B LMO7 FAM110A HSPA12B EDNRB

7.92e-061936353a5ad8ffad441e30a6e1bd017da7720ad57f6c57
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN LMO7 MMRN2 HSPA12B EDNRB

8.54e-06196635b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN LMO7 MMRN2 HSPA12B EDNRB

8.54e-06196635ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN LMO7 MMRN2 HSPA12B EDNRB

8.54e-06196635039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HNF1B GCNT3 LMO7 SGPP2 ASTN2

8.75e-061976357e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Calb1-Excitatory_Neuron.Sc17a7.Calb1-Lpl-Cadm2_(Layer_2/3,_Cadm2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AK9 PKD1L2 FCRL6

4.33e-0548633bbfc33299ea8e6895dd4d21a7dd38bec33563127
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A XKR7 DSCAM GRM1

4.51e-05139634a1945b07f177cde40e7eea03a19236ce76165857
ToppCellPBMC-Mild-cDC_7|Mild / Compartment, Disease Groups and Clusters

CACNA1A XKR7 LMO7 FAAH

4.90e-0514263458f66f35646f281e64d634e6c26adbd1d4e6c830
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

MIA3 SGPP2 PIWIL2 RALGAPA2

5.18e-0514463408005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellmild_COVID-19_(asymptomatic)-Treg|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

CD28 SGPP2 ASPM ASTN2

5.32e-051456342d0903009e918500facfd017ff31f2cec1e76131
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2|TCGA-Pancreas / Sample_Type by Project: Shred V9

XKR7 DSCAM ADGRF3 GRM1

5.46e-05146634bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

XKR7 DSCAM ADGRF3 GRM1

5.46e-0514663472c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A RELN DSCAM GRM1

5.76e-05148634d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

LMO7 MMRN2 LGR5 EDNRB

7.24e-0515763484f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCell18-Airway-Epithelial-Bud_tip_progenitor|Airway / Age, Tissue, Lineage and Cell class

MYO5A ANO5 FCRL6 EDNRB

7.61e-05159634e715cadff8e7d5ebe4c2198dbdfd3ca41ecb8a6a
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A RELN DSCAM ANKFN1

7.61e-051596345335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCNT3 DSCAM LMO7 PGAM2

7.61e-0515963460b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN ANO5 GRM1 GRM4

7.98e-05161634bf70be1de418615b5442ec684552551edaf1f072
ToppCell5'-Adult-SmallIntestine-Epithelial-neuro-epithelial-EECs|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A DSCAM TERT PGAM2

8.18e-05162634478cf560ef33c5c324142c76417447d4a571a2c9
ToppCellIonocyte-iono-3|World / Class top

DNHD1 MYO5A ASTN2 VEGFB

8.98e-051666349c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A CACNA1E DSCAM ANKFN1

9.20e-051676343edb0570e583bb527165bcd8a4c25a042054043b
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1A CACNA1E TMPRSS11E PGAM2

9.20e-05167634c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPUSD4 MMRN2 PHLPP1 RALGAPA2

9.63e-05169634f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A FAM110A PGAM2 ANGPTL7

1.03e-0417263424ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A FAM110A PGAM2 ANGPTL7

1.03e-04172634db5a31cafce4346fe459d7f35210823fd7004439
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E LGR5 PGAM2 ANGPTL7

1.05e-041736344f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1E LGR5 PGAM2 ANGPTL7

1.05e-041736349bbea566964281f47bf75d665b7d69ba8326e207
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGPP2 PKD2L1 PGAM2 FAAH

1.08e-04174634cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A XKR7 GRM4 PGAM2

1.13e-04176634d54543510c804474c5c32e007cd699e75fc5aaba
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM MMRN2 HSPA12B TERT

1.13e-041766347292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSCAM MMRN2 HSPA12B TERT

1.13e-0417663488ca2f83d8301633232735f39b0683efe49d0b86
ToppCell3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN MAPK12 HSPA12B EDNRB

1.15e-04177634dfaed388926ce050730492a532824af68bf4feff
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR2B RALGAPA2 HSPA12B EDNRB

1.20e-041796349fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGS22 AK9 ANKFN1 DNAH11

1.20e-041796345e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKR7 CD28 FAM110A FAAH

1.20e-041796346f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

XKR7 DSCAM SNAP91 PGAM2

1.20e-04179634af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCellLV|World / Chamber and Cluster_Paper

VWA8 LMO7 SGPP2 ANO5

1.23e-041806345ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-4|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

IL17REL KDM5A GRM1 LGR5

1.23e-04180634886ebaf9cf8992e8dd13fca799a1d1a2a9ce73d8
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Tac1_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

XKR7 GCNT3 ANGPTL7

1.23e-0468633506a7727f281136f5f6e397af99c219854a01e26
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Tac1_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

XKR7 GCNT3 ANGPTL7

1.23e-0468633a5528ececdfa798ecc939482ee80a963dcc3c429
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Tac1_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

XKR7 GCNT3 ANGPTL7

1.23e-04686334a4bd488ab6dfae61e654e42bf374382bccb66cc
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNF1B RGS22 ANKFN1 DNAH11

1.25e-04181634e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNF1B RGS22 ANKFN1 DNAH11

1.25e-0418163411cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HNF1B RGS22 ANKFN1 DNAH11

1.25e-041816345ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR2B RALGAPA2 HSPA12B EDNRB

1.31e-041836342d0d3b486498a7903fa9a1f48b189291da49c430
ToppCellwk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CACNA1A XKR7 SGPP2 PGAM2

1.34e-041846349e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E NBAS CD28 FAAH

1.34e-0418463442cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN HTR2B MMRN2 EDNRB

1.36e-04185634dec60254204014083ff3b4aec0cc75410950a486
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1A HNF1B LGR5 FAAH

1.36e-04185634d42f6722a6771752cd744146a09e2ead9b7252bc
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1E DSCAM PGAM2 ITIH4

1.36e-04185634110d5f02759c8235b14aea524ea47199696094ea
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PHLPP1 RALGAPA2 LGR5 VEGFB

1.36e-04185634636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

CD28 SGPP2 RHBDD2 PHLPP1

1.36e-04185634e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN HTR2B MMRN2 ITIH4

1.36e-0418563459acaf025353405948dc34ccccf37ec5c08ea903
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN HTR2B MMRN2 EDNRB

1.36e-04185634201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN HTR2B MMRN2 EDNRB

1.36e-04185634334f006c3ef33338ff8d649309d3f448733a3a99
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|356C / Donor, Lineage, Cell class and subclass (all cells)

MMRN2 RALGAPA2 HSPA12B EDNRB

1.39e-04186634f0b78c7ee20279970ea8961bf59acb5262f2dce5
ToppCelldroplet-Kidney-nan-3m-Endothelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B EDNRB

1.39e-04186634d72cdbb6d79ab33a5823c42e93c2ba566244f64c
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

RELN SNAP91 OVOS2 EDNRB

1.39e-041866346b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCell356C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|356C / Donor, Lineage, Cell class and subclass (all cells)

MMRN2 RALGAPA2 HSPA12B EDNRB

1.39e-041866342b3c814a7dee8286ea113c63dc3de5daf0257d37
ToppCellPCW_10-12-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1E XKR7 DSCAM PGAM2

1.42e-0418763498477ba04a42a8da80a72f41a182429f46283595
ToppCellEndothelial-A-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

MAPK12 MMRN2 OVOS2 HSPA12B

1.42e-04187634febe0b99a6a815ce687160a0e7af55228b1d5beb
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

SNAP91 VWA8 LMO7 ANO5

1.42e-0418763478cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A MMRN2 HSPA12B LGR5

1.42e-04187634e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HTR2B LMO7 HSPA12B EDNRB

1.45e-04188634db0652f000d459493321b53239326706eace598c
ToppCelldroplet-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B EDNRB

1.45e-04188634ca3be1942b179b512ab242acded31f1e3748c753
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1E RELN HSPA12B EDNRB

1.45e-04188634524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1E RELN HSPA12B EDNRB

1.45e-04188634d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

RELN MAPK12 MMRN2 EDNRB

1.48e-041896349a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCelldroplet-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR2B LMO7 HSPA12B EDNRB

1.48e-041896347b6cb745c0a637d6addc105a79059ed488fced39
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B EDNRB

1.48e-0418963488c0dda28f072368c0df30fc82ee3af9c7670f6c
ToppCelldroplet-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B EDNRB

1.48e-0418963491261fe86f0d54b9697f85bb4d3ebdc8975b1bfa
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A RELN MYO5A GRM1

1.48e-04189634f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

RGS22 AK9 ANKFN1 DNAH11

1.48e-041896343e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellfacs-GAT-Fat-24m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 MMRN2 HSPA12B EDNRB

1.51e-04190634da2fcd4a2cc6e45c8174109d892f1424e39919a1
ToppCellfacs-GAT-Fat-24m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 MMRN2 HSPA12B EDNRB

1.51e-041906343395b2ff6ffadf84cdb1b5a37a5b6be05b56c30f
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B LGR5

1.51e-04190634cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCellfacs-GAT-Fat-24m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 MMRN2 HSPA12B EDNRB

1.51e-04190634e584eaccbc22aa7f7a4340ed8a2a8b45ddca93f4
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PHLPP1 HSPA12B LGR5 EDNRB

1.51e-041906340a351609a72fd638c84b2435782e312ee6a33aac
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B LGR5

1.51e-041906345bf3d0beee69879c95265d07fba023626a7cc808
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR2B RALGAPA2 HSPA12B EDNRB

1.51e-041906346b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCelldroplet-Kidney-nan-3m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B EDNRB

1.54e-04191634dc58d45fafd224d2761aefbe0ce79f66b50c1c03
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 HSPA12B EDNRB DNAH11

1.54e-04191634df8cdbc26443e55a203cbafa21b0952a2a55b9bf
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 MMRN2 HSPA12B EDNRB

1.54e-04191634a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN HTR2B MMRN2 EDNRB

1.54e-0419163479b399496bd7322a1d53c43378f48695fd09a5d9
ToppCellfacs-Trachea-24m-Endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN HTR2B MMRN2 EDNRB

1.54e-041916349c6d5d045781c6506ae80e318427ef1e0d87f45c
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E RELN HTR2B MMRN2

1.54e-0419163448823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN HTR2B MMRN2 EDNRB

1.54e-041916341b1e943709d0c3283a980c7c965ef1f110506a29
ToppCellfacs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 MMRN2 HSPA12B EDNRB

1.54e-04191634827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCelldroplet-Kidney-KIDNEY-1m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK12 MMRN2 HSPA12B EDNRB

1.54e-04191634767269dbd799e08c4ebba13e8c968fb148acf182
DrugAC1L1KS5

CACNA1A CACNA1E HNF1B MAPK12 SNAP91 GRM1 GRM4 EDNRB

3.35e-06334628CID000005631
Drug2-aminoethoxydiphenylborane

CD28 GRM1

7.30e-062622ctd:C504876
DrugThioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A

BPTF DSCAM KDM5A XPO6 ASPM ACAP2

1.19e-051876264989_DN
Drugnifedipine

CACNA1A CACNA1E MYO5A GRM1 GRM4 ITIH4 EDNRB VEGFB

1.63e-05415628CID000004485
DrugDCG-IV

CACNA1A CACNA1E GRM1 GRM4

3.56e-0568624CID000115114
DrugRS)-2-chloro-5-hydroxyphenylglycine

RELN GRM1 GRM4

3.74e-0524623CID003645780
DrugAC 110

CACNA1A CACNA1E

4.36e-054622CID000022860
DrugCbpg

GRM1 GRM4

4.36e-054622CID005311040
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1E

1.26e-053612DOID:0111181 (implicated_via_orthology)
Diseasenon-small cell lung carcinoma

BPTF DSCAM ADGRF3 TERT

1.80e-0575614EFO_0003060
Diseasemetabolite measurement

BPTF NBAS MAPK12 DSCAM TMPRSS11E PKD2L1 PKD1L2 FAAH

1.95e-05560618EFO_0004725
Diseaselymphopenia (implicated_via_orthology)

CD28 EDNRB

2.52e-054612DOID:614 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1E

2.52e-054612DOID:6364 (implicated_via_orthology)
Diseasemacula measurement

BPTF GCNT3 SNAP91 PKD2L1 INO80

4.55e-05189615EFO_0008375
DiseaseBipolar Disorder

CACNA1A RELN TRANK1 DSCAM ASTN2 GRM4 ITIH4

5.67e-05477617C0005586
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1E

8.77e-057612DOID:0050951 (implicated_via_orthology)
Diseaseinterleukin 1 receptor antagonist measurement

TRANK1 ASTN2 DNAH11

1.83e-0453613EFO_0004754
Diseasemeningitis

CACNA1E CD28

2.28e-0411612MONDO_0021108
DiseaseAL amyloidosis

SMARCD3 DNAH11

2.74e-0412612MONDO_0019438
Diseasepulmonary hypertension (is_marker_for)

CD28 TERT EDNRB

3.20e-0464613DOID:6432 (is_marker_for)
DiseaseHuntington Disease

RELN FAAH

5.60e-0417612C0020179
DiseaseUterine leiomyoma, estrogen-receptor positive breast cancer

ASTN2 TERT

6.30e-0418612EFO_1000649, HP_0000131
Diseaseresponse to supplemental oxygen

TMPRSS11E ASTN2

7.03e-0419612EFO_0009796
Diseasecoagulation factor measurement

ASPM FAM110A

7.80e-0420612EFO_0004634
Diseasesystemising measurement

NBAS DSCAM

8.61e-0421612EFO_0010221
Disease5alpha-androstan-3beta,17beta-diol disulfate measurement

TMPRSS11E FAM200A

9.46e-0422612EFO_0021115
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM1 GRM4

1.03e-0323612C0393672
DiseaseEpilepsy, Lateral Temporal

GRM1 GRM4

1.03e-0323612C0393682
DiseaseUncinate Epilepsy

GRM1 GRM4

1.03e-0323612C0014558
DiseaseEpilepsy, Temporal Lobe

GRM1 GRM4

1.03e-0323612C0014556
Diseasebrain volume measurement

CACNA1A RPUSD4 RELN MAPK12 ASTN2 DNAH11

1.42e-03595616EFO_0006930
Diseasemultiple myeloma

SMARCD3 ANO5 DNAH11

1.63e-03112613EFO_0001378
Diseaseamyotrophic lateral sclerosis (is_marker_for)

BPTF ITIH4

1.65e-0329612DOID:332 (is_marker_for)
DiseaseDrug habituation

DSCAM XPO6 FAAH

1.76e-03115613C0013170
DiseaseSubstance-Related Disorders

DSCAM XPO6 FAAH

1.76e-03115613C0236969
DiseaseDrug abuse

DSCAM XPO6 FAAH

1.76e-03115613C0013146
DiseaseDrug Use Disorders

DSCAM XPO6 FAAH

1.76e-03115613C0013222
DiseaseDrug Dependence

DSCAM XPO6 FAAH

1.76e-03115613C1510472
DiseaseSubstance Dependence

DSCAM XPO6 FAAH

1.76e-03115613C0038580
DiseaseSubstance Use Disorders

DSCAM XPO6 FAAH

1.76e-03115613C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

DSCAM XPO6 FAAH

1.76e-03115613C0029231
DiseasePrescription Drug Abuse

DSCAM XPO6 FAAH

1.76e-03115613C4316881
DiseaseSubstance abuse problem

DSCAM XPO6 FAAH

1.80e-03116613C0740858
DiseaseHirschsprung Disease

RELN EDNRB

1.88e-0331612C0019569
Diseasetemporal lobe epilepsy (biomarker_via_orthology)

CACNA1A GRM1

1.88e-0331612DOID:3328 (biomarker_via_orthology)
DiseaseUterine leiomyoma, breast carcinoma

ASTN2 TERT

2.00e-0332612EFO_0000305, HP_0000131
Diseaselower urinary tract symptom, benign prostatic hyperplasia

HNF1B TERT

2.00e-0332612EFO_0000284, EFO_0008008

Protein segments in the cluster

PeptideGeneStartEntry
KVTKYWASLRNLVVS

CACNA1A

591

O00555
YNSRATAFIKITVVW

HTR2B

166

P41595
VYWLVWRVVVRNKIS

ADGRF3

791

Q8IZF5
RVDAWKLTTQYRRTV

ANO5

706

Q75V66
KITKYWASLRNLVVS

CACNA1E

581

Q15878
TVAFIIFWVRSKRSR

CD28

171

P10747
DIVRALKWNYVSTVA

GRM4

211

Q14833
DVIIYVRRSIDNWTK

DNAH11

1331

Q96DT5
SIDRYRAVASWSRIK

EDNRB

196

P24530
RATNSSWVVVFKALV

SNAP91

66

O60641
KNYVTLVSRLNVWQA

DNHD1

741

Q96M86
AWIKAVQTSIATAYR

ACAP2

351

Q15057
ITWRYRLQTVKSLAG

BPTF

1891

Q12830
VRWLSQGKVLSRVYE

FAM200A

301

Q8TCP9
EIRAARLIQTTWRKY

ASPM

1266

Q8IZT6
VNAALVIQKYWRRVL

ASPM

1316

Q8IZT6
SVLQSIIKIQRWYRA

ASPM

1846

Q8IZT6
VQNAVIKIQSSYRRW

ASPM

2311

Q8IZT6
TIKQKVIAWSRARYI

ARMCX5

216

Q6P1M9
LVFTVALYAQRRWQK

ASTN2

221

O75129
VVVTRNRRSSAYKWK

ITIH4

801

Q14624
YKRAQILVADTWSVL

C9orf64

206

Q5T6V5
KVIRRFWSQKTLYTQ

INO80

606

Q9ULG1
WTIIQRRKSGLVSFY

ANGPTL7

171

O43827
SYWVDRRRKAILVQV

IL17REL

116

Q6ZVW7
VYQVKQKVLTSLAWR

MMRN2

106

Q9H8L6
VIAAALLVYVRSWRK

FCRL6

321

Q6DN72
YGVSVVERNARVIKW

FAM110A

266

Q9BQ89
ETDRRVKNVLITLYW

LMO7

161

Q8WWI1
DYWIVVKRNSRKTVT

OVOS2

181

Q6IE36
VETALRRSSVNFVKW

HSPA12B

426

Q96MM6
AVTRKVVQVYRKWIL

RALGAPA2

421

Q2PPJ7
VYQRQWRKSAVNVAS

NBAS

556

A2RRP1
GVKVRAQSYDTWVSR

KDM5A

731

P29375
IYTSERFQNWKRITV

RELN

1716

P78509
VVYVLVVIWARRKDA

PKD1L2

1356

Q7Z442
VFIASKLVRVVYASW

GCNT3

186

O95395
KLVRVVYASWSRVQA

GCNT3

191

O95395
IEVYRKTVIAQWRAL

FAAH

451

O00519
LDIVKRYNWTYVSAV

GRM1

216

Q13255
LVSLRKQTYVWTRSK

LGR5

831

O75473
VTEVRVYNWFANRRK

HNF1B

291

P35680
LSRNRQYSVWVVAVT

DSCAM

1251

O60469
FRTRQVVKKYWAITV

RPUSD4

176

Q96CM3
LARYITQAWKCIRVE

AK9

46

Q5TCS8
FLWRTVLVVKDRVYQ

MIA3

1196

Q5JRA6
YRLAKLVSQVRWSKS

RGS22

141

Q8NE09
VASINLTLTKWYSRV

PIWIL2

761

Q8TC59
YTSVLKRAIRTLWAI

PGAM2

56

P15259
SAIVQALWQYVKTNR

SMARCD3

281

Q6STE5
SLQVLYSWFKVVTRN

SGPP2

346

Q8IWX5
SVNAAVVTRYKVEWS

ANKFN1

296

Q8N957
VYTRVTALRDWITSK

TMPRSS11E

406

Q9UL52
VSLAWTLASYQKVLR

XKR7

271

Q5GH72
KSEALRNWQVYRLVT

RHBDD2

51

Q6NTF9
IRTVKLIRYVSNWDF

PKD2L1

336

Q9P0L9
VTTWRTKYETDAIQR

MYH16

531

Q9H6N6
HQRKVVSWIDVYTRA

VEGFB

31

P49765
FTEYLRWLRQVSKVA

PHLPP1

621

O60346
KQQRTVYRLTLVKAW

TYW1

566

Q9NV66
WQRYLRQSLEVVAKV

XPO6

486

Q96QU8
KQLYTAITRARVNLW

TRANK1

1641

O15050
SWKIVRVSENFRVIA

VWA8

226

A3KMH1
TQRSLLVVCSKYWRV

WDR7

226

Q9Y4E6
YRKSVWSKLQSIGIR

TERT

576

O14746
DIRTQVSAIVQRKYW

TRIM16L

126

Q309B1
VTKTAWEVRAVYRDL

MAPK12

16

P53778
FLRRTKAATIIQKYW

MYO5A

811

Q9Y4I1