Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopolyphosphatase activity

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

3.41e-1151635GO:0000298
GeneOntologyMolecularFunctionbis(5'-adenosyl)-hexaphosphatase activity

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

3.41e-1151635GO:0034431
GeneOntologyMolecularFunctiondiphosphoinositol-polyphosphate diphosphatase activity

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

3.41e-1151635GO:0008486
GeneOntologyMolecularFunctionbis(5'-adenosyl)-pentaphosphatase activity

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.03e-1061635GO:0034432
GeneOntologyMolecularFunctionpyrophosphatase activity

TDRD9 KIF26A COQ8B RNF213 MCM6 ATP10B NUDT4B MFN1 GTPBP2 NUDT11 NUDT4 NUDT3 RECQL5 NUDT10 NAV3 GNB4 ATP11A DNAH6 RHOT1 DNAH11

1.73e-0583916320GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

TDRD9 KIF26A COQ8B RNF213 MCM6 ATP10B NUDT4B MFN1 GTPBP2 NUDT11 NUDT4 NUDT3 RECQL5 NUDT10 NAV3 GNB4 ATP11A DNAH6 RHOT1 DNAH11

1.76e-0584016320GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

TDRD9 KIF26A COQ8B RNF213 MCM6 ATP10B NUDT4B MFN1 GTPBP2 NUDT11 NUDT4 NUDT3 RECQL5 NUDT10 NAV3 GNB4 ATP11A DNAH6 RHOT1 DNAH11

1.76e-0584016320GO:0016818
GeneOntologyMolecularFunctioninositol bisdiphosphate tetrakisphosphate diphosphatase activity

NUDT4 NUDT3

6.62e-0521632GO:0052841
GeneOntologyMolecularFunctioninositol diphosphate pentakisphosphate diphosphatase activity

NUDT4 NUDT3

6.62e-0521632GO:0052842
GeneOntologyMolecularFunctioninositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity

NUDT4 NUDT3

6.62e-0521632GO:0052848
GeneOntologyMolecularFunctioninositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity

NUDT4 NUDT3

6.62e-0521632GO:0052845
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRAF3IP2 RNF213 ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 UBR5 TRIM56 MGRN1

2.49e-0437216311GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

TRAF3IP2 ATG16L1 RNF213 ZSWIM2 MIB2 BIRC7 FBXL21P RNF157 TRIM33 RNF5 UBR5 TRIM56 MGRN1

3.04e-0451216313GO:0019787
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR3

3.93e-0441632GO:0005219
GeneOntologyMolecularFunctionaminoacyltransferase activity

TRAF3IP2 ATG16L1 RNF213 ZSWIM2 MIB2 BIRC7 FBXL21P RNF157 TRIM33 RNF5 UBR5 TRIM56 MGRN1

4.37e-0453216313GO:0016755
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRAF3IP2 RNF213 ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 UBR5 TRIM56 MGRN1

4.40e-0439816311GO:0061659
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

TRAF3IP2 RNF213 ZSWIM2 MIB2 BIRC7 FBXL21P RNF157 TRIM33 RNF5 UBR5 TRIM56 MGRN1

5.23e-0447316312GO:0004842
GeneOntologyMolecularFunctionATP-dependent activity

EP400 TDRD9 KIF26A TMEM94 COQ8B RNF213 MCM6 ATP10B MSH6 RECQL5 NAV3 ATP11A DNAH6 DNAH11

5.25e-0461416314GO:0140657
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR3

9.72e-0461632GO:0048763
GeneOntologyMolecularFunctionATP hydrolysis activity

TDRD9 KIF26A COQ8B RNF213 MCM6 ATP10B RECQL5 NAV3 ATP11A DNAH6 DNAH11

1.02e-0344116311GO:0016887
GeneOntologyMolecularFunctiondeubiquitinase activator activity

WDR20 DMWD

1.35e-0371632GO:0035800
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

TDRD9 KIF26A COQ8B RNF213 MCM6 ATP10B MFN1 GTPBP2 RECQL5 NAV3 GNB4 ATP11A DNAH6 RHOT1 DNAH11

1.74e-0377516315GO:0017111
GeneOntologyBiologicalProcessadenosine 5'-(hexahydrogen pentaphosphate) metabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.90e-1151635GO:1901910
GeneOntologyBiologicalProcessadenosine 5'-(hexahydrogen pentaphosphate) catabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.90e-1151635GO:1901911
GeneOntologyBiologicalProcessdiadenosine pentaphosphate catabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.90e-1151635GO:1901907
GeneOntologyBiologicalProcessdiadenosine pentaphosphate metabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.90e-1151635GO:1901906
GeneOntologyBiologicalProcessdiadenosine hexaphosphate catabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.90e-1151635GO:1901909
GeneOntologyBiologicalProcessdiadenosine hexaphosphate metabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.90e-1151635GO:1901908
GeneOntologyBiologicalProcessdiphosphoinositol polyphosphate metabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

2.90e-1151635GO:0071543
GeneOntologyBiologicalProcessdiadenosine polyphosphate catabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

1.73e-1061635GO:0015961
GeneOntologyBiologicalProcessdiadenosine polyphosphate metabolic process

NUDT4B NUDT11 NUDT4 NUDT3 NUDT10

3.56e-0991635GO:0015959
GeneOntologyBiologicalProcessinositol phosphate metabolic process

NUDT4B NUDT11 NUDT4 NUDT3 SYNJ2 NUDT10

3.35e-06521636GO:0043647
GeneOntologyBiologicalProcesspolyol metabolic process

ISYNA1 NUDT4B NUDT11 GK2 NUDT4 NUDT3 SYNJ2 NUDT10

6.11e-061231638GO:0019751
GeneOntologyBiologicalProcessautophagosome organization

ATG16L1 ATG2B RNF5 IFT88 PIK3C2B PIK3C3 ELAPOR1 BECN1

8.68e-061291638GO:1905037
GeneOntologyBiologicalProcesspost-translational protein modification

TRAF3IP2 USP34 ATG16L1 SLF1 RNF213 ZSWIM2 MIB2 BIRC7 KBTBD2 FBXL21P RNF157 CCNF FEM1B TRIM33 RNF5 UBR5 TRIM56 N4BP1 KLHL12 FBXL2 USP3 KLHL18 MGRN1

1.29e-05107416323GO:0043687
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

TRAF3IP2 USP34 SLF1 RNF213 ZSWIM2 MIB2 BIRC7 KBTBD2 FBXL21P RNF157 CCNF FEM1B TRIM33 RNF5 UBR5 TRIM56 N4BP1 KLHL12 FBXL2 USP3 KLHL18 MGRN1

1.54e-05100916322GO:0070647
GeneOntologyBiologicalProcessprotein ubiquitination

TRAF3IP2 RNF213 ZSWIM2 MIB2 BIRC7 KBTBD2 FBXL21P RNF157 CCNF FEM1B TRIM33 RNF5 UBR5 TRIM56 N4BP1 KLHL12 FBXL2 KLHL18 MGRN1

2.33e-0581116319GO:0016567
GeneOntologyBiologicalProcessphosphatidylinositol-3-phosphate biosynthetic process

PIK3C2B SYNJ2 PIK3C3 BECN1

2.46e-05221634GO:0036092
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

TRAF3IP2 SLF1 RNF213 ZSWIM2 MIB2 BIRC7 KBTBD2 FBXL21P RNF157 CCNF FEM1B TRIM33 RNF5 UBR5 TRIM56 N4BP1 KLHL12 FBXL2 KLHL18 MGRN1

2.66e-0589316320GO:0032446
GeneOntologyBiologicalProcessvacuole organization

ATG16L1 ATG2B ATP10B ARSB RNF5 IFT88 PIK3C2B PIK3C3 ELAPOR1 BECN1

3.01e-0524916310GO:0007033
GeneOntologyBiologicalProcessautophagosome assembly

ATG16L1 ATG2B RNF5 IFT88 PIK3C3 ELAPOR1 BECN1

5.02e-051211637GO:0000045
GeneOntologyBiologicalProcesspolyol catabolic process

GK2 NUDT3 SYNJ2

1.01e-04121633GO:0046174
GeneOntologyBiologicalProcessprotein targeting to lysosome

SNX16 PIK3C3 BECN1 VPS53

1.29e-04331634GO:0006622
GeneOntologyBiologicalProcessorganelle assembly

TEKT3 ATG16L1 ATG2B RNF213 FASTKD2 MEF2A MEF2C DNALI1 DNAJB13 GK2 RNF5 KASH5 NDC80 IFT88 PIK3C3 DNAAF10 SYNE2 SEC23IP ELAPOR1 AP1S2 BECN1

2.57e-04113816321GO:0070925
GeneOntologyBiologicalProcesscellular response to metal ion

CPNE8 XRCC4 MEF2A MEF2C RYR1 RYR3 KCNJ1 BECN1

3.61e-042191638GO:0071248
GeneOntologyBiologicalProcessinositol phosphate catabolic process

NUDT3 SYNJ2

3.69e-0441632GO:0071545
GeneOntologyCellularComponentaxoneme

TEKT3 ATG16L1 DNALI1 DNAJB13 KIFAP3 IFT88 PIK3C3 DNAH6 DNAH11

3.69e-052071639GO:0005930
GeneOntologyCellularComponentciliary plasm

TEKT3 ATG16L1 DNALI1 DNAJB13 KIFAP3 IFT88 PIK3C3 DNAH6 DNAH11

3.84e-052081639GO:0097014
GeneOntologyCellularComponentphagophore assembly site

ATG16L1 ATG2B PIK3C3 BECN1

2.37e-04391634GO:0000407
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type II

PIK3C3 BECN1

3.59e-0441632GO:0034272
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III, type I

PIK3C3 BECN1

3.59e-0441632GO:0034271
GeneOntologyCellularComponentextrinsic component of membrane

TRAF3IP2 TRIO RYR1 JAK1 PIK3C2B PIK3C3 GNB4 BECN1

4.58e-042301638GO:0019898
GeneOntologyCellularComponent9+2 motile cilium

TEKT3 ATG16L1 DNALI1 DNAJB13 GK2 IFT88 DNAH6 DNAH11

5.74e-042381638GO:0097729
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

TEKT3 ATG16L1 DNALI1 DNAJB13 KIFAP3 IFT88 PIK3C3 DNAH6 DNAH11

8.81e-043171639GO:0032838
GeneOntologyCellularComponentsupramolecular fiber

TEKT3 KIF26A MEF2C RYR1 RYR3 KIFAP3 FBN1 EML5 SYNJ2 SYNE2 PAK1 NAV3 JAKMIP1 MYO18B FERMT2 DNAH6 UPP2 KRT38 KRT37 DNAH11

8.83e-04117916320GO:0099512
GeneOntologyCellularComponentextrinsic component of cytoplasmic side of plasma membrane

TRAF3IP2 RYR1 JAK1 GNB4

9.55e-04561634GO:0031234
GeneOntologyCellularComponentsupramolecular polymer

TEKT3 KIF26A MEF2C RYR1 RYR3 KIFAP3 FBN1 EML5 SYNJ2 SYNE2 PAK1 NAV3 JAKMIP1 MYO18B FERMT2 DNAH6 UPP2 KRT38 KRT37 DNAH11

9.59e-04118716320GO:0099081
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class III

PIK3C3 BECN1

1.24e-0371632GO:0035032
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex

PIK3C2B PIK3C3 BECN1

1.47e-03291633GO:0005942
GeneOntologyCellularComponentouter acrosomal membrane

TEKT3 IFT88

1.64e-0381632GO:0002081
GeneOntologyCellularComponentI band

RYR1 RYR3 SYNE2 PAK1 MYO18B FERMT2

1.95e-031661636GO:0031674
GeneOntologyCellularComponentjunctional membrane complex

RYR1 RYR3

2.10e-0391632GO:0030314
GeneOntologyCellularComponentcytoplasmic region

TEKT3 ATG16L1 DNALI1 DNAJB13 KIFAP3 IFT88 PIK3C3 DNAH6 DNAH11

2.12e-033601639GO:0099568
GeneOntologyCellularComponentSCF ubiquitin ligase complex

FBXL21P CCNF FBXL20 FBXL2

2.19e-03701634GO:0019005
GeneOntologyCellularComponentcytoplasmic side of membrane

TRAF3IP2 RYR1 RYR3 JAK1 GNB4 FERMT2 BECN1

2.23e-032301637GO:0098562
MousePhenoabnormal heart atrium morphology

ATG16L1 TMEM94 MEF2C RBM20 RYR1 FBN1 IFT88 ATP11A MYO18B DNAH11 MGRN1

9.19e-0623212811MP:0003105
DomainARM-type_fold

USP34 NOC2L CIP2A TTI2 ARFGEF1 RYR3 ARFGEF3 KIFAP3 PIK3C2B PIK3C3 IFRD2 HEATR5B TNPO3 XPOT

1.47e-0633916114IPR016024
DomainNUDIX_hydrolase_CS

NUDT11 NUDT4 NUDT3 NUDT10

2.50e-06121614IPR020084
DomainMADS_MEF2-like

MEF2B MEF2A MEF2C

2.50e-0641613IPR033896
DomainMADS_BOX_1

MEF2B MEF2A MEF2C

1.23e-0561613PS00350
DomainMADS

MEF2B MEF2A MEF2C

1.23e-0561613SM00432
DomainSRF-TF

MEF2B MEF2A MEF2C

1.23e-0561613PF00319
DomainMADS_BOX_2

MEF2B MEF2A MEF2C

1.23e-0561613PS50066
DomainP-loop_NTPase

EP400 TDRD9 KIF26A RNF213 MCM6 LRRK1 NLRP2 NLRC4 MFN1 ORC5 MSH6 NLRP9 GTPBP2 SAMD9L MYO15B RECQL5 NAV3 MYO18B DNAH6 RHOT1 DNAH11

1.32e-0584816121IPR027417
DomainTF_MADSbox

MEF2B MEF2A MEF2C

2.15e-0571613IPR002100
DomainNUDIX_BOX

NUDT11 NUDT4 NUDT3 NUDT10

4.94e-05241614PS00893
DomainNUDIX

NUDT11 NUDT4 NUDT3 NUDT10

4.94e-05241614PF00293
DomainWD40_repeat_dom

ATG16L1 LRRK1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

5.51e-0529716111IPR017986
DomainNUDIX

NUDT11 NUDT4 NUDT3 NUDT10

6.86e-05261614PS51462
Domain-

EP400 TDRD9 RNF213 MCM6 LRRK1 NLRP2 NLRC4 MFN1 ORC5 MSH6 NLRP9 GTPBP2 SAMD9L RECQL5 NAV3 DNAH6 RHOT1 DNAH11

7.97e-05746161183.40.50.300
DomainWD40

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

8.57e-0525916110PF00400
Domain-

NUDT11 NUDT4 NUDT3 NUDT10

9.27e-052816143.90.79.10
DomainNUDIX_hydrolase_dom-like

NUDT11 NUDT4 NUDT3 NUDT10

9.27e-05281614IPR015797
DomainNUDIX_hydrolase_dom

NUDT11 NUDT4 NUDT3 NUDT10

1.07e-04291614IPR000086
DomainLRR_6

NLRP2 NLRP9 PHLPP1 FBXL20 FBXL2

1.10e-04551615PF13516
DomainWD40

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

1.14e-0426816110SM00320
DomainWD40_repeat

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

1.28e-0427216110IPR001680
Domain-

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 NUP133 GNB4 ELP2 DMWD

1.52e-04333161112.130.10.10
DomainWD_REPEATS_1

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

1.53e-0427816110PS00678
DomainWD_REPEATS_2

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

1.58e-0427916110PS50082
DomainWD_REPEATS_REGION

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

1.58e-0427916110PS50294
DomainWD40/YVTN_repeat-like_dom

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 NUP133 GNB4 ELP2 DMWD

1.60e-0433516111IPR015943
DomainRyanodine_rcpt

RYR1 RYR3

2.20e-0431612IPR003032
DomainRyanrecept_TM4-6

RYR1 RYR3

2.20e-0431612IPR009460
DomainRyR

RYR1 RYR3

2.20e-0431612PF02026
DomainRR_TM4-6

RYR1 RYR3

2.20e-0431612PF06459
DomainRyan_recept

RYR1 RYR3

2.20e-0431612IPR013333
DomainSEC7

IQSEC3 ARFGEF1 ARFGEF3

3.24e-04161613PS50190
DomainSec7

IQSEC3 ARFGEF1 ARFGEF3

3.24e-04161613SM00222
DomainSec7_dom

IQSEC3 ARFGEF1 ARFGEF3

3.24e-04161613IPR000904
DomainHJURP_C

MEF2A MEF2C

4.38e-0441612IPR022102
DomainDCB_dom

ARFGEF1 ARFGEF3

4.38e-0441612IPR032629
DomainDUF4195

ZNF280A ZNF280D

4.38e-0441612IPR025243
DomainSec7_C

ARFGEF1 ARFGEF3

4.38e-0441612IPR015403
DomainDUF1981

ARFGEF1 ARFGEF3

4.38e-0441612PF09324
DomainHJURP_C

MEF2A MEF2C

4.38e-0441612PF12347
DomainDUF4195

ZNF280A ZNF280D

4.38e-0441612PF13836
DomainDCB

ARFGEF1 ARFGEF3

4.38e-0441612PF16213
DomainBTB

KLHL6 KCTD19 RCBTB2 KBTBD2 ZBTB42 KLHL12 KLHL18

4.81e-041601617PS50097
DomainBTB-kelch_protein

KLHL6 KBTBD2 KLHL12 KLHL18

5.05e-04431614IPR017096
DomainBTB

KLHL6 RCBTB2 KBTBD2 ZBTB42 KLHL12 KLHL18

9.63e-041311616PF00651
DomainNACHT

NLRP2 NLRC4 NLRP9

9.81e-04231613PS50837
DomainNACHT_NTPase

NLRP2 NLRC4 NLRP9

9.81e-04231613IPR007111
DomainFBOX

FBXL21P CCNF FBXL20 FBXL2

1.04e-03521614SM00256
DomainRIH_assoc-dom

RYR1 RYR3

1.08e-0361612IPR013662
DomainXpo1

TNPO3 XPOT

1.08e-0361612PF08389
DomainIns145_P3_rec

RYR1 RYR3

1.08e-0361612PF08709
DomainRIH_assoc

RYR1 RYR3

1.08e-0361612PF08454
DomainRIH_dom

RYR1 RYR3

1.08e-0361612IPR000699
DomainIns145_P3_rcpt

RYR1 RYR3

1.08e-0361612IPR014821
DomainRyanodine_recept-rel

RYR1 RYR3

1.08e-0361612IPR015925
Domain-

RYR1 RYR3

1.08e-03616121.25.10.30
DomainRYDR_ITPR

RYR1 RYR3

1.08e-0361612PF01365
DomainExportin-1/Importin-b-like

TNPO3 XPOT

1.08e-0361612IPR013598
DomainZF_RING_2

RNF213 ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 TRIM56 MGRN1

1.14e-032981619PS50089
DomainSKP1/BTB/POZ

KLHL6 KCTD19 RCBTB2 KBTBD2 ZBTB42 KLHL12 KLHL18

1.28e-031891617IPR011333
DomainRING

RNF213 ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 TRIM56 MGRN1

1.34e-033051619SM00184
DomainSWIM

ZSWIM3 ZSWIM2

1.51e-0371612PF04434
DomainKelch

KLHL6 KBTBD2 KLHL12 KLHL18

1.57e-03581614SM00612
DomainGal_Oxase/kelch_b-propeller

KLHL6 KBTBD2 KLHL12 KLHL18

1.67e-03591614IPR011043
DomainBACK

KLHL6 KBTBD2 KLHL12 KLHL18

1.78e-03601614SM00875
Domain-

ZFYVE27 RNF213 ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 TRIM56 USP3 MGRN1

1.81e-03449161113.30.40.10
DomainBACK

KLHL6 KBTBD2 KLHL12 KLHL18

1.89e-03611614IPR011705
DomainBACK

KLHL6 KBTBD2 KLHL12 KLHL18

1.89e-03611614PF07707
DomainZnf_U1

ZNF407 RBM20 ZFHX2

1.95e-03291613IPR003604
DomainZnF_U1

ZNF407 RBM20 ZFHX2

1.95e-03291613SM00451
DomainPI3K_C2

PIK3C2B PIK3C3

2.00e-0381612SM00142
DomainPI3K_C2_dom

PIK3C2B PIK3C3

2.00e-0381612IPR002420
DomainPI3K_C2

PIK3C2B PIK3C3

2.00e-0381612PF00792
DomainPI3K_C2

PIK3C2B PIK3C3

2.00e-0381612PS51547
DomainZnf_RING

RNF213 ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 TRIM56 MGRN1

2.12e-033261619IPR001841
DomainZnf_RING/FYVE/PHD

ZFYVE27 RNF213 ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 TRIM56 USP3 MGRN1

2.15e-0345916111IPR013083
DomainARM-like

CIP2A TTI2 ARFGEF1 KIFAP3 IFRD2 HEATR5B TNPO3 XPOT

2.41e-032701618IPR011989
DomainPI3Ka

PIK3C2B PIK3C3

2.55e-0391612PF00613
DomainPI3Ka

PIK3C2B PIK3C3

2.55e-0391612SM00145
DomainZF_SWIM

ZSWIM3 ZSWIM2

2.55e-0391612PS50966
DomainZnf_SWIM

ZSWIM3 ZSWIM2

2.55e-0391612IPR007527
Domain-

PIK3C2B PIK3C3

2.55e-03916121.25.40.70
DomainF-box

FBXL21P CCNF FBXL20 FBXL2

2.67e-03671614PF00646
DomainKelch_1

KLHL6 KBTBD2 KLHL12 KLHL18

3.14e-03701614PF01344
DomainKelch_1

KLHL6 KBTBD2 KLHL12 KLHL18

3.14e-03701614IPR006652
Domain-

CIP2A ARFGEF1 KIFAP3 IFRD2 HEATR5B TNPO3 XPOT

3.18e-0322216171.25.10.10
DomainMIR

RYR1 RYR3

3.18e-03101612PF02815
DomainMIR_motif

RYR1 RYR3

3.18e-03101612IPR016093
DomainPI_Kinase

PIK3C2B PIK3C3

3.18e-03101612IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3C2B PIK3C3

3.18e-03101612IPR001263
DomainMIR

RYR1 RYR3

3.18e-03101612PS50919
DomainMIR

RYR1 RYR3

3.18e-03101612SM00472
DomainPIK_HELICAL

PIK3C2B PIK3C3

3.18e-03101612PS51545
Domainzf-C3HC4

RNF213 ZSWIM2 BIRC7 RNF157 RNF5 TRIM56 MGRN1

3.25e-032231617PF00097
DomainFBOX

FBXL21P CCNF FBXL20 FBXL2

3.47e-03721614PS50181
DomainZF_RING_1

ZSWIM2 MIB2 BIRC7 RNF157 TRIM33 RNF5 TRIM56 MGRN1

3.80e-032911618PS00518
DomainATPase_P-typ_transduc_dom_A

TMEM94 ATP10B ATP11A

3.94e-03371613IPR008250
DomainE1-E2_ATPase

TMEM94 ATP10B ATP11A

3.94e-03371613PF00122
DomainF-box_dom

FBXL21P CCNF FBXL20 FBXL2

4.02e-03751614IPR001810
DomainQuinoprot_gluc/sorb_DH

EML5 TRIM56

4.61e-03121612IPR011041
PathwayREACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL

NUDT11 NUDT4 NUDT3 NUDT10

9.42e-07101184MM14709
PathwayREACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL

NUDT11 NUDT4 NUDT3 NUDT10

9.42e-07101184M27051
PathwayREACTOME_INOSITOL_PHOSPHATE_METABOLISM

ISYNA1 NUDT11 NUDT4 NUDT3 NUDT10 MTMR9

2.79e-06481186M26964
PathwayREACTOME_INOSITOL_PHOSPHATE_METABOLISM

ISYNA1 NUDT11 NUDT4 NUDT3 NUDT10

4.85e-05481185MM14589
Pubmed

Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.

NUDT11 NUDT4 NUDT3 NUDT10

4.88e-104165412370170
Pubmed

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.

NUDT11 NUDT4 NUDT10

1.05e-073165312121577
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NOC2L CIP2A TTI2 ARFGEF1 LMBR1 MCM6 SAMHD1 ARFGEF3 SCAP NDC1 RNF5 UBR5 SEC23IP NUP133 TVP23C HEATR5B VPS53 TNPO3 XPOT

1.29e-079421651931073040
Pubmed

Neurotoxin-induced selective ubiquitination and regulation of MEF2A isoform in neuronal stress response.

MEF2B MEF2A MEF2C

4.18e-074165322764880
Pubmed

Regional chromosomal assignments for four members of the MADS domain transcription enhancer factor 2 (MEF2) gene family to human chromosomes 15q26, 19p12, 5q14, and 1q12-q23.

MEF2B MEF2A MEF2C

4.18e-07416538575763
Pubmed

Transcriptional activity of MEF2 during mouse embryogenesis monitored with a MEF2-dependent transgene.

MEF2B MEF2A MEF2C

4.18e-074165310207130
Pubmed

Spine growth in the anterior cingulate cortex is necessary for the consolidation of contextual fear memory.

MEF2B MEF2A MEF2C

4.18e-074165321531906
Pubmed

Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation.

MEF2B MEF2A MEF2C

4.18e-07416537643214
Pubmed

MEF2 transcription factors regulate distinct gene programs in mammalian skeletal muscle differentiation.

MEF2B MEF2A MEF2C

4.18e-074165325416778
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

ATG16L1 NOC2L CIP2A AAK1 SNX16 MEF2A TRIM33 UBR5 PIK3C2B DNAAF10 WDR20 SEC23IP AP1S2 GNB4 HEATR5B DMWD FERMT2 BECN1 MTMR9

5.60e-0710381651926673895
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TRIO CIP2A RNF213 RBM20 MSH6 NDC1 SSU72 DNAAF10 WDR20 SYNE2 PLCL2 NUP133 PHLPP1 GNB4 ELP2 DMWD MTMR9 XPOT FTSJ3

6.56e-0710491651927880917
Pubmed

Membrane hyperpolarization triggers myogenin and myocyte enhancer factor-2 expression during human myoblast differentiation.

MEF2B MEF2A MEF2C

1.04e-065165315084602
Pubmed

The MEF2B homologue differentially expressed in mouse embryonal carcinoma cells.

MEF2B MEF2A MEF2C

1.04e-06516537646512
Pubmed

Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle.

MEF2B MEF2A MEF2C

1.04e-06516538993831
Pubmed

Galpha13 regulates MEF2-dependent gene transcription in endothelial cells: role in angiogenesis.

MEF2B MEF2A MEF2C

1.04e-065165319093215
Pubmed

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

MEF2B MEF2A MEF2C

1.04e-065165312694204
Pubmed

Expression of MEF2 genes during human cardiac development.

MEF2B MEF2A MEF2C

1.04e-065165310458488
Pubmed

Regulatory role of MEF2D in serum induction of the c-jun promoter.

MEF2B MEF2A MEF2C

1.04e-06516537760790
Pubmed

Cooperation between MEF2 and PPARgamma in human intestinal beta,beta-carotene 15,15'-monooxygenase gene expression.

MEF2B MEF2A MEF2C

1.04e-065165316504037
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TRAF3IP2 ATG16L1 CIP2A ATG2B AAK1 MCM6 XRCC4 DNALI1 KIFAP3 CYFIP1 EML5 IFT88 DNAAF10 TRIM56 WDR20 SEC23IP PLCL2 NUP133 FERMT2 VPS53 TNPO3

1.33e-0613211652127173435
Pubmed

The expression of MEF2 genes is implicated in CNS neuronal differentiation.

MEF2B MEF2A MEF2C

2.08e-06616539013788
Pubmed

Transcription enhancer factor 1 binds multiple muscle MEF2 and A/T-rich elements during fast-to-slow skeletal muscle fiber type transitions.

MEF2B MEF2A MEF2C

3.62e-067165312861002
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

USP34 ZFYVE27 EP400 ARFGEF1 RNF213 KBTBD2 ARFGEF3 WDR3 TRIM33 GTPBP2 NDC1 UBR5 WDR20 SEC23IP FERMT2

4.94e-067771651535844135
Pubmed

MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis.

MEF2B MEF2A MEF2C

5.77e-068165330205047
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

ISYNA1 CIP2A ATG2B COQ8B MCM6 FASTKD2 ORC5 MSH6 SEC23IP NUP133 VPS53 XPOT MGRN1

7.13e-066061651336538041
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

NOC2L WDR3 MSH6 NDC1 NDC80 UBR5 NUP133 FTSJ3

7.88e-06210165816565220
Pubmed

The Wnt Signaling Antagonist Dapper1 Accelerates Dishevelled2 Degradation via Promoting Its Ubiquitination and Aggregate-induced Autophagy.

ATG16L1 PIK3C3 BECN1

8.63e-069165325825496
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

ARFGEF1 RNF213 SAMHD1 ARFGEF3 UBR5 XPOT

1.08e-05104165631240132
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

IQSEC3 AAK1 TRIM33 PLCL2 ZFHX2 ATP11A

1.08e-05104165610470851
Pubmed

Myocyte Enhancer Factor 2c Regulates Dendritic Complexity and Connectivity of Cerebellar Purkinje Cells.

MEF2B MEF2A MEF2C

1.23e-0510165330276662
Pubmed

Connexins modulate autophagosome biogenesis.

ATG16L1 PIK3C3 BECN1

1.23e-0510165324705551
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

MCM6 WDR3 TRIM33 ORC5 MSH6 CYFIP1 NDC1 SEC23IP NUP133 ELP2 TNPO3 XPOT

1.64e-055601651235241646
Pubmed

Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C.

MEF2B MEF2A MEF2C

1.68e-051116539162005
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

USP34 EP400 TRIO KIF26A TMEM94 MIB2 LRRK1 ZBTB42 ELAC2 RYR1 SCAP SLC45A3 PIK3C2B SSU72 IFRD2 DMWD TNPO3

2.20e-0511051651735748872
Pubmed

A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.

ZSWIM2 MIB2 RNF157 RNF5 TRIM56 MGRN1

2.21e-05118165619690564
Pubmed

Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice.

MEF2A MEF2C

2.24e-052165216469744
Pubmed

Restoration of impaired endothelial myocyte enhancer factor 2 function rescues pulmonary arterial hypertension.

MEF2A MEF2C

2.24e-052165225336633
Pubmed

MEF2B is a component of a smooth muscle-specific complex that binds an A/T-rich element important for smooth muscle myosin heavy chain gene expression.

MEF2B MEF2A

2.24e-05216529430690
Pubmed

GA binding protein augments autophagy via transcriptional activation of BECN1-PIK3C3 complex genes.

PIK3C3 BECN1

2.24e-052165225046113
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

2.24e-05216529489997
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

2.24e-052165212640042
Pubmed

Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.

NUDT11 NUDT10

2.24e-052165212689335
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

2.24e-052165214592949
Pubmed

Regulation of myocyte enhancer factor-2 transcription factors by neurotoxins.

MEF2A MEF2C

2.24e-052165221741404
Pubmed

The evolutionarily conserved domain of Beclin 1 is required for Vps34 binding, autophagy and tumor suppressor function.

PIK3C3 BECN1

2.24e-052165216874027
Pubmed

Identification of a candidate therapeutic autophagy-inducing peptide.

PIK3C3 BECN1

2.24e-052165223364696
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

2.24e-05216529799464
Pubmed

Overexpression of myocyte enhancer factor 2 and histone hyperacetylation in hepatocellular carcinoma.

MEF2A MEF2C

2.24e-052165217611778
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

2.24e-052165217118445
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

2.24e-052165211500519
Pubmed

An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.

NUDT11 NUDT10

2.24e-052165212105228
Pubmed

Novel inducers of BECN1-independent autophagy: cis-unsaturated fatty acids.

PIK3C3 BECN1

2.24e-052165225714112
Pubmed

Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes.

ATG16L1 BECN1

2.24e-052165223658055
Pubmed

Miro1 functions as an inhibitory regulator of MFN at elevated mitochondrial Ca2+ levels.

MFN1 RHOT1

2.24e-052165234431132
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

2.24e-052165212565913
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

2.24e-05216529192302
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

2.24e-05216527556644
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

2.24e-052165215894801
Pubmed

Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking.

PIK3C3 BECN1

2.24e-052165216390869
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

2.24e-05216529817784
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 EP400 COQ8B RNF213 JAK1 TRIM33 MSH6 GTPBP2 ARSB EML5 UBR5 TRIM56 WDR20 ELF3 VPS53 RHOT1 FTSJ3

2.49e-0511161651731753913
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ARFGEF3 NDC80 PIK3C3 TRIM56 SYNE2 NUP133 N4BP1 VPS53

2.85e-05251165829778605
Pubmed

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.

CIP2A TTI2 ARFGEF1 RNF213 ARFGEF3 TNPO3 XPOT

2.87e-05183165723956138
Pubmed

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.

MEF2B MEF2A MEF2C

3.67e-0514165312130539
Pubmed

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock.

ATG16L1 JAK1 BECN1

3.67e-0514165331346084
Pubmed

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.

ATG16L1 PIK3C3 BECN1

4.58e-0515165330245008
Pubmed

Hem-1 complexes are essential for Rac activation, actin polymerization, and myosin regulation during neutrophil chemotaxis.

ARFGEF1 PIK3C3 BECN1

4.58e-0515165316417406
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

USP34 EP400 KIF26A AAK1 FASTKD2 LRRK1 KBTBD2 SLC7A6 TRIM33 SYNJ2 MGRN1

4.88e-055291651114621295
Pubmed

Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.

KLHL6 TRAF3IP2 BIRC7 ZBTB42 KLHL18 MGRN1

5.33e-05138165628786561
Pubmed

Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.

RNF213 MIB2 FBXL21P CCNF FBXL20

5.46e-0585165519028597
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CPNE8 TRIO MAP4K3 NOC2L CIP2A AAK1 KBTBD2 WDR3 NDC80 UBR5 SYNJ2 FERMT2 MTMR9 FTSJ3

6.08e-058531651428718761
Pubmed

A ubiquitin-based effector-to-inhibitor switch coordinates early brain, craniofacial, and skin development.

RCBTB2 KBTBD2 PAK1 KLHL12 KLHL18

6.11e-0587165537495603
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

SAMHD1 MIB2 JAK1 GTPBP2 IFRD2 N4BP1 RHOT1 FTSJ3

6.63e-05283165821903422
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR3

6.69e-053165218403125
Pubmed

Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.

RYR1 RYR3

6.69e-053165211171121
Pubmed

GADD45A inhibits autophagy by regulating the interaction between BECN1 and PIK3C3.

PIK3C3 BECN1

6.69e-053165226636486
Pubmed

Ring finger protein 5 activates sterol regulatory element-binding protein 2 (SREBP2) to promote cholesterol biosynthesis via inducing polyubiquitination of SREBP chaperone SCAP.

SCAP RNF5

6.69e-053165232054686
Pubmed

VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy.

PIK3C3 BECN1

6.69e-053165223315026
Pubmed

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy.

PIK3C3 BECN1

6.69e-053165216179260
Pubmed

The nuclear localization domain of the MEF2 family of transcription factors shows member-specific features and mediates the nuclear import of histone deacetylase 4.

MEF2A MEF2C

6.69e-053165211792813
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR3

6.69e-05316527876312
Pubmed

An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133.

MEF2A MEF2C

6.69e-053165218093911
Pubmed

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis.

ATG16L1 BECN1

6.69e-053165222258505
Pubmed

In vivo analysis of MEF2 transcription factors in synapse regulation and neuronal survival.

MEF2A MEF2C

6.69e-053165222496871
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR3

6.69e-053165222948152
Pubmed

Myocyte enhancer factor-2 and serum response factor binding elements regulate fast Myosin heavy chain transcription in vivo.

MEF2B MEF2A

6.69e-053165215728583
Pubmed

Human gastric cancer progression and stabilization of ATG2B through RNF5 binding facilitated by autophagy-associated CircDHX8.

ATG2B RNF5

6.69e-053165238866787
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR3

6.69e-053165210788707
Pubmed

Protein phosphorylation and expression profiling by Yin-yang multidimensional liquid chromatography (Yin-yang MDLC) mass spectrometry.

USP34 GVINP1

6.69e-053165217203969
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR3

6.69e-05316527621815
Pubmed

The genomic and clinical landscape of fetal akinesia.

IQSEC3 RYR3

6.69e-053165231680123
Pubmed

Identification of inactivating mutations in the JAK1, SYNJ2, and CLPTM1 genes in prostate cancer cells using inhibition of nonsense-mediated decay and microarray analysis.

JAK1 SYNJ2

6.69e-053165216102578
Pubmed

Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c.

MEF2A MEF2C

6.69e-053165227989458
Pubmed

Phosphorylation-dependent regulation of stability and transforming potential of ETS transcriptional factor ESE-1 by p21-activated kinase 1.

PAK1 ELF3

6.69e-053165217491012
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR3

6.69e-053165210473538
Pubmed

Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.

RYR1 RYR3

6.69e-053165218313230
Pubmed

Human myocyte-specific enhancer factor 2 comprises a group of tissue-restricted MADS box transcription factors.

MEF2B MEF2A

6.69e-05316521516833
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR3

6.69e-053165218434746
Pubmed

HLA-C expression in extravillous trophoblasts is determined by an ELF3-NLRP2/NLRP7 regulatory axis.

NLRP2 ELF3

6.69e-053165239052836
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR3

6.69e-05316529204703
InteractionGPR17 interactions

ZFYVE27 CIP2A TTI2 COQ8B ARFGEF1 LMBR1 RNF213 MFN1 ARFGEF3 TVP23C HEATR5B VPS53 TNPO3 XPOT

6.71e-0828316114int:GPR17
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2B MEF2A MEF2C

1.16e-0641213649
GeneFamilyMyocyte enhancer factor 2 proteins|MADS box family

MEF2B MEF2A MEF2C

2.90e-06512131086
GeneFamilyWD repeat domain containing

ATG16L1 WDR76 WDR3 SCAP EML5 DNAAF10 WDR20 GNB4 ELP2 DMWD

1.06e-0526212110362
GeneFamilyNudix hydrolase family

NUDT11 NUDT4 NUDT3 NUDT10

1.83e-05241214667
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR3

1.33e-0431212287
GeneFamilyDyneins, axonemal

DNALI1 DNAH6 DNAH11

1.86e-04171213536
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL6 RCBTB2 KBTBD2 ZBTB42 KLHL12 KLHL18

2.84e-041341216861
GeneFamilyF-box and leucine rich repeat proteins

FBXL21P FBXL20 FBXL2

3.56e-04211213558
GeneFamilyNLR family

NLRP2 NLRC4 NLRP9

6.04e-04251213666
GeneFamilyPhosphatidylinositol 3-kinase subunits

PIK3C2B PIK3C3

1.21e-0381212831
GeneFamilyAutophagy related

ATG16L1 ATG2B BECN1

1.38e-033312131022
GeneFamilyZinc fingers SWIM-type|Mitogen-activated protein kinase kinase kinases

ZSWIM3 ZSWIM2

1.55e-039121290
GeneFamilyRing finger proteins

RNF213 BIRC7 RNF157 TRIM33 RNF5 TRIM56 MGRN1

2.53e-03275121758
GeneFamilyKelch like|BTB domain containing

KLHL6 KLHL12 KLHL18

2.78e-03421213617
GeneFamilyATPase phospholipid transporting

ATP10B ATP11A

4.41e-031512121210
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK1 MYO15B FERMT2

4.56e-035012131293
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

ZSWIM2 MIB2

6.34e-0318121291
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

USP34 TRIO ARFGEF1 XRCC4 MEF2A KIFAP3 TRIM33 ORC5 MSH6 NDC80 UBR5 SYNJ2 PIK3C3 SYNE2 NUP133 NAV3 PHLPP1 N4BP1 FERMT2 ZNF292

4.45e-0785616420M4500
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP

CPNE8 SLF1 NOC2L CIP2A MCM6 SAMHD1 WDR76 MEF2C CCNF JAK1 MSH6 NDC1 NDC80 IFRD2 NUP133

3.82e-0657816415M2368
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP

CPNE8 SLF1 NOC2L CIP2A MCM6 SAMHD1 WDR76 MEF2C CCNF JAK1 MSH6 NDC1 NDC80 IFRD2 NUP133

5.63e-0659716415MM1309
CoexpressionNAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_UP

KLHL6 USP34 CPNE8 TRIO AAK1 SAMHD1 MEF2C SAMD9L CYFIP1 RNF5 PIK3C3 SEC23IP AP1S2 ALDH1A1

1.29e-0556216414M41008
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 MEF2B MEF2C GUCA2B PIK3C2B RECQL5 CCR7 JAKMIP1

3.45e-071791648de3245e1ee269e422de0308d0dd3623e4e9eb182
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 MEF2B MEF2C GUCA2B PIK3C2B RECQL5 CCR7 JAKMIP1

3.45e-071791648c41c11171dfb40e5ddea6bf97d9373eb03a2321b
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

TRIO RNF213 SAMHD1 SAMD9L TRIM56 SYNE2 N4BP1 ZNF292

4.08e-0718316488f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellCalu_3-infected-SARSCoV2|infected / Cell line, Condition and Strain

RNF213 SAMHD1 GTPBP2 SAMD9L TRIM56 SYNE2 GNB4 N4BP1

5.65e-0719116482da876d26f37a00dbdf1ee79d724306e8b20f304
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-3|TCGA-Skin / Sample_Type by Project: Shred V9

RCBTB2 RBM20 FEM1B NUDT3 IFT88 PHLPP1 ALDH1A1

2.11e-061591647fb222c42f66901852b01cec073ec0732245ee973
ToppCellfacs-Lung-Endomucin-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 MEF2B GUCA2B PIK3C2B RECQL5 CCR7 JAKMIP1

4.13e-0617616479b58734017ceabe81f490dd0b9f3192bc903d455
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

USP34 ZSWIM3 S1PR5 SAMD9L SYNE2 SEC23IP PHLPP1

4.78e-061801647974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

USP34 ZSWIM3 S1PR5 SAMD9L SYNE2 SEC23IP PHLPP1

4.78e-061801647703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF26A LMBR1 ZNF407 SNX16 ELAC2 WDR20 DMWD

5.73e-06185164760206c7322b4ddb2010040aac70561df842c9843
ToppCellCOVID-19-Heart-CM_4|Heart / Disease (COVID-19 only), tissue and cell type

TDRD9 NUDT4 PLCL2 AP1S2 ELF3 ATP11A MYO18B

6.82e-0619016473729648a17093b438398b82e32bbccc3af7b8c5d
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLF1 CIP2A WDR76 RNF157 CCNF NDC80 JAKMIP1

7.06e-061911647bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LMBR1 ZNF302 IFT88 PIK3C3 IFRD2 PAK1 XPOT

7.06e-06191164739ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCellfacs-Brain_Myeloid-Hippocampus|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2A MEF2C JAK1 CYFIP1 ARSB NAV3 MYO18B

8.08e-061951647a1478021a3ed0e779716393124ca2a7770c433b7
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

TRAF3IP2 TDRD9 PRSS36 SYNE2 ELF3 DNAH6 MGRN1

8.63e-0619716476b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

RNF213 S1PR5 NUDT11 SAMD9L SYNE2 ELAPOR1 N4BP1

8.92e-06198164776d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCellCV|World / Virus stimulation, Condition and Cluster

RNF213 SAMHD1 JAK1 S1PR5 SAMD9L SSU72 SYNE2

8.92e-0619816476a28193af35abec5c029129930c2ca6febaafde2
ToppCellCD8+_Memory_T_cell-CV|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

RNF213 SAMHD1 JAK1 S1PR5 SAMD9L SSU72 SYNE2

8.92e-0619816473d1749f5106f0912f4a74615863853949f52c73d
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 AAK1 ARFGEF1 RNF213 ZNF407 SYNE2 ZNF292

9.22e-061991647f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

USP34 SLF1 TRIO RNF213 MEF2C UBR5 SYNE2

9.53e-062001647dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

SLF1 RNF213 SAMHD1 SAMD9L PIK3C2B SYNE2 FERMT2

9.53e-062001647edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

AAK1 RNF213 JAK1 S1PR5 SAMD9L SYNE2 JAKMIP1

9.53e-062001647109f673a4967ffa52270a0b4f818b3461288db44
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RNF213 SAMHD1 MEF2C JAK1 SAMD9L PIK3C2B SYNE2

9.53e-0620016473585484c7e24e941708bee471ca607d8ccee74e6
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

AAK1 LMBR1 SAMHD1 VWDE GVINP1 SYNE2

1.98e-051501646c922dbb4c9c12ccf08bd5f6168b20606c605d052
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC3 RYR1 S1PR5 SAMD9L N4BP1 MYO18B

2.14e-05152164682a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCellPND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RFX7 WDR76 RYR1 RNF157 ARSB PAK1

2.48e-051561646af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

USP34 REP15 ZFYVE27 AAK1 SYNE2 FBXL20

3.06e-051621646b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TEKT3 ZNF302 RBM20 S1PR5 SYNE2 JAKMIP1

3.28e-051641646c4ad98106e8663caf7c1c15d30ec633d8bd8cf57
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TEKT3 ZNF302 RBM20 S1PR5 SYNE2 JAKMIP1

3.28e-051641646ed7277f8980f96f5b3e4eed025d46d0942e123d7
ToppCellCOVID-CD8-exh_CD4|COVID / Condition, Cell_class and T cell subcluster

CIP2A WDR76 NLRP2 SYNJ2 TVP23C FBXL20

3.51e-0516616464ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B ZSWIM2 SAMHD1 RYR1 CCR7 JAKMIP1

3.63e-0516716463c4183a8225bae37b9f5341ebd1b95409ced2022
ToppCellfacs-Kidney-nan-24m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEF2B ZSWIM2 SAMHD1 RYR1 CCR7 JAKMIP1

3.63e-05167164628e9670586ff551b700c794313d27eedbfa1286b
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AAK1 SAMHD1 NLRC4 RYR1 S1PR5 JAKMIP1

4.01e-051701646059f7ae615342ea19f43b0a405cd7272251a78a9
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF26A RFX7 RNF157 ZFHX2 AP1S2 ALDH1A1

4.14e-051711646b51bbeacb172e8b5de519ada85543d7ae9914b3c
ToppCelldroplet-Fat-Mat-18m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 NDC80 GUCA2B KCNJ1 ELAPOR1 CCR7

4.28e-051721646226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCEA2 KIF26A XRCC4 MEF2C KIFAP3 VPS53

4.71e-05175164698dc3b6f69a29d587f503898f09912700950e3d9
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF1 S1PR5 SAMD9L PIK3C2B SYNE2 PHLPP1

4.71e-051751646cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDHR2 GTPBP2 SAMD9L NUDT4 ATP11A ALDH1A1

4.86e-0517616467622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCellT_cells-ISG-high_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

RNF213 ATP10B SAMD9L TRIM56 N4BP1 CCR7

5.34e-051791646af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCellCOVID-19_Convalescent-PLT_1|World / Disease Group and Platelet Clusters

MEF2C WDR3 GTPBP2 TVP23C AP1S2 CCR7

5.34e-051791646d0f2764c6fc5d61fd69e9231b3603a80ac373f65
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AAK1 RNF213 SAMHD1 JAK1 SYNE2 CCR7

5.68e-051811646a6c8b33a392de3df2f179317e329e45d3d8c6f52
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

USP34 AAK1 LMBR1 RNF213 UBR5 SYNE2

5.68e-051811646f2315414e714ac86211546a935660c4be6e85f1b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KCTD19 CIP2A WDR76 CCNF NDC80 ELAPOR1

6.41e-05185164630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEF2B ISYNA1 MEF2C DNAJB13 S1PR5 DNAH11

6.61e-0518616466568358812f0ca4e0161a1a1b29682fbced35c79
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CIP2A SAMHD1 WDR76 RYR1 CCNF NDC80

6.80e-05187164673931a5ea73799095daff100b5f18853c57c74dc
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 ARFGEF1 RNF213 ZNF407 SYNE2 KLHL18

7.01e-051881646ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

RNF213 SAMD9L TRIM56 SYNE2 N4BP1 CCR7

7.01e-0518816466f8946d4710f6e32c937213f99b790b098b8819c
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRK1 MEF2A MEF2C PAK1 AP1S2 CCR7

7.01e-0518816469fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF280D RCBTB2 MEF2A RNF157 MSH6 USP3

7.01e-05188164659b71462338a7efbacf46577cb07e9db3363afee
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

RYR3 NUDT11 FBN1 SLC45A3 NUDT10 ALDH1A1

7.22e-0518916462157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SAMHD1 MEF2C PRSS36 RYR1 NUDT4 ARSB

7.43e-0519016462d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CPNE8 KIF26A LRRK1 FBN1 PIK3C2B SYNJ2

7.43e-051901646aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B1|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

LMBR1 ZNF302 IFT88 PIK3C3 IFRD2 XPOT

7.43e-0519016462434b8ad2976eab7d9147012c28454ab29670709
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

KLHL6 TRIO LRRK1 MEF2A MEF2C CCR7

7.43e-0519016461e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZSWIM2 ATP10B ELF3 ALDH1A1 DNAH6 DNAH11

7.43e-0519016462fdc024d3d673a0134b74b4c5a63afe924995730
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TMEM94 MCM6 WDR3 DNAAF10 PAK1

7.60e-05118164508bdf7bc3c9dcbc0f690658fe14e6cc4b9581698
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TMEM94 MCM6 WDR3 DNAAF10 PAK1

7.60e-0511816453b077ad5c68c01b3fcc93f203cb130bb90705af9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AAK1 LMBR1 FASTKD2 RNF157 SYNE2 CCR7

7.65e-051911646696921a4f160b6b55698652488ed781e855e5e51
ToppCellChildren_(3_yrs)-Immune-monocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RCBTB2 SAMHD1 LRRK1 MEF2C PLCL2 PAK1

8.10e-05193164658e1930a1d80ad3729ab9604ac8ebf7308232a3d
ToppCellIIH-CD8|IIH / Condition, Cell_class and T cell subcluster

SLF1 RNF213 MIB2 S1PR5 SYNE2 JAKMIP1

8.10e-051931646343ac8c6dc6d7c7a944a14de65f1d4ea3dfafe86
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PCDHGA11 AAK1 RNF213 TRIM33 SYNE2 ZNF292

8.10e-0519316469337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellIIH-CD8-CD8_1|IIH / Condition, Cell_class and T cell subcluster

SLF1 RNF213 MIB2 S1PR5 SYNE2 JAKMIP1

8.10e-051931646c5a4926003906d6726155f19061b73fb45d9962c
ToppCellHSPCs-Ery_prog.|World / Lineage and Cell class

ISYNA1 NOC2L SLC45A3 IFRD2 GNB4 FTSJ3

8.10e-051931646484c2e0daedc6cb0d50d164add8c1658123a60f9
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

MAP4K3 RNF213 SAMHD1 MEF2A SAMD9L USP3

8.33e-051941646d1366b169d14011194e61d16b6b0953349febc78
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRRK1 MEF2A MEF2C PAK1 AP1S2 CCR7

8.57e-0519516467bb3bdfb8caaae357b1f7841d8d00936c4373dfe
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MEF2C GTPBP2 SAMD9L AP1S2 GNB4 ALDH1A1

8.57e-05195164619413dc6aa0010686cdfa0c750ef0a7a76caf308
ToppCellT/NK_cells-CD8+_Naive_T_cell|World / Lineage and Cell class

AAK1 RNF213 MIB2 JAK1 S1PR5 SYNE2

8.57e-05195164643f11068beea076e9caeb1572215c3f65c9308e1
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

SLF1 CIP2A WDR76 CCNF NDC80 JAKMIP1

8.57e-0519516467e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIP2A MCM6 WDR76 CCNF NUDT4 NDC80

8.57e-0519516467ae732f100e9a3c6062be5b877efa1ec9d5b3958
ToppCellPBMC-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

RNF213 SAMHD1 MEF2A MEF2C SAMD9L PAK1

8.57e-051951646674355ca00314bde90ef7f6ddb83afe2d5323130
ToppCellCOVID-19_Moderate-CD8+_T_activated|World / disease group, cell group and cell class

RNF213 S1PR5 SAMD9L SYNE2 N4BP1 JAKMIP1

8.57e-051951646070c5d3bdbd4ea54a579c01c37fb99bcf823982e
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRK1 MEF2A MEF2C PAK1 AP1S2 CCR7

8.57e-051951646d579150d176e6bd81004b5146de4901ca13a3c3e
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIP2A MCM6 WDR76 CCNF NUDT4 NDC80

8.57e-051951646043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 PCDHGA11 AAK1 RNF213 SYNE2 ZNF292

9.06e-05197164657ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

AAK1 RNF213 S1PR5 SYNE2 CCR7 JAKMIP1

9.06e-0519716462e9677b4b9a7c88db16416e5f114a2031ec3bc24
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

AAK1 RNF213 S1PR5 SYNE2 CCR7 JAKMIP1

9.06e-0519716464c9919914079e76b1d2220b249e0d0b0d9bf4bc0
ToppCellBronchial_Brush-Epithelial|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DNALI1 ARFGEF3 SYNE2 ELF3 ALDH1A1 DNAH11

9.06e-051971646272c7f4e582ef57564450540242b0db766b78328
ToppCellCOVID-19_Moderate-CD8+_T_activated|COVID-19_Moderate / disease group, cell group and cell class

RNF213 S1PR5 SAMD9L SYNE2 N4BP1 JAKMIP1

9.06e-0519716464711ecb157e907758a5021248ae8b043d17672c6
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIP2A RCBTB2 WDR76 CCNF NUDT4 NDC80

9.06e-0519716469b2c67de46bd59bf56c81a0d10b84cf4a041c120
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SAMHD1 MEF2A MEF2C CYFIP1 NUDT3 GNB4

9.06e-0519716469838dbd1623babf8de7e9126a28fe5d3666bce42
ToppCellCOVID-19_Severe-NK_activated|World / disease group, cell group and cell class

RNF213 JAK1 S1PR5 SAMD9L SYNE2 PLCL2

9.06e-051971646a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 JAK1 S1PR5 SAMD9L SYNE2 PLCL2

9.32e-0519816460e918e9db9b884f5328d438e90efe065e27266ee
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RNF213 JAK1 S1PR5 SAMD9L SYNE2 PLCL2

9.32e-051981646ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

RNF213 JAK1 S1PR5 SAMD9L SYNE2 PLCL2

9.32e-051981646fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RNF213 JAK1 S1PR5 SAMD9L SYNE2 PLCL2

9.32e-0519816461ef3a6bd681c223eed58300348adfef89df5563c
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF213 GTPBP2 SAMD9L AP1S2 GNB4 ALDH1A1

9.58e-051991646933201d32eda12a89660bdbae9114a95cc428a38
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK_activated|COVID-19_Severe / Disease group, lineage and cell class

RNF213 JAK1 S1PR5 SAMD9L SYNE2 PLCL2

9.58e-051991646edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCellVE-CD4-antiviral_CD4|VE / Condition, Cell_class and T cell subcluster

RNF213 SAMHD1 SAMD9L SYNE2 N4BP1 CCR7

9.58e-051991646056a0538ca5e825ae6195b4c76c208708a014533
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

USP34 TRIO MAP4K3 ZNF407 RFX7 UBR5

9.58e-05199164694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF213 MEF2A MEF2C RYR1 SAMD9L CYFIP1

9.58e-051991646e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF213 S1PR5 SAMD9L SYNE2 N4BP1 JAKMIP1

9.85e-052001646d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

LRRK1 MEF2A MEF2C RYR1 CYFIP1 NAV3

9.85e-052001646a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RNF213 KBTBD2 MEF2C JAK1 SAMD9L PIK3C2B

9.85e-0520016462d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

LRRK1 MEF2A MEF2C RYR1 CYFIP1 NAV3

9.85e-052001646dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

LRRK1 MEF2A MEF2C RYR1 CYFIP1 NAV3

9.85e-0520016463bba5219453322198e8fdb0921d5f8c403598751
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 RNF213 SAMHD1 SAMD9L SYNE2 ZNF292

9.85e-05200164612f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellVE|World / Condition, Cell_class and T cell subcluster

RNF213 SAMHD1 JAK1 SAMD9L SYNE2 N4BP1

9.85e-0520016468ae7cb81de3ffac5acdf3466d4b516d80cac95d3
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

LRRK1 MEF2A MEF2C RYR1 CYFIP1 NAV3

9.85e-05200164621bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellCOVID_non-vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CIP2A MCM6 WDR76 CCNF MSH6 NDC80

9.85e-05200164604bf9e6a0fbd792b49eed63dabba5d6fafed8c07
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated|COVID-19_Severe / Disease, condition lineage and cell class

RNF213 JAK1 S1PR5 SAMD9L SYNE2 PLCL2

9.85e-0520016466a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCellBiopsy_IPF-Epithelial|Biopsy_IPF / Sample group, Lineage and Cell type

DNALI1 ARFGEF3 ELF3 ALDH1A1 DNAH6 DNAH11

9.85e-05200164676f1ac00b34d07057d8da03d276438b719b46b1d
Diseaseunipolar depression, bipolar disorder, mental or behavioural disorder

IFT88 ALDH1A1 MYO18B

3.09e-0661603EFO_0000677, EFO_0003761, MONDO_0004985
Diseaseintellectual disability (implicated_via_orthology)

ZNF280A MEF2B ZNF280D MEF2A MEF2C ELP2

3.42e-06751606DOID:1059 (implicated_via_orthology)
DiseaseSarcomatoid Renal Cell Carcinoma

POMC BIRC7 RYR1 SYNE2 PAK1 NAV3 ALDH1A1

6.59e-061281607C1266043
DiseaseChromophobe Renal Cell Carcinoma

POMC BIRC7 RYR1 SYNE2 PAK1 NAV3 ALDH1A1

6.59e-061281607C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

POMC BIRC7 RYR1 SYNE2 PAK1 NAV3 ALDH1A1

6.59e-061281607C1266044
DiseasePapillary Renal Cell Carcinoma

POMC BIRC7 RYR1 SYNE2 PAK1 NAV3 ALDH1A1

6.59e-061281607C1306837
DiseaseRenal Cell Carcinoma

POMC BIRC7 RYR1 SYNE2 PAK1 NAV3 ALDH1A1

6.59e-061281607C0007134
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

POMC BIRC7 RYR1 SYNE2 PAK1 NAV3 ALDH1A1

1.70e-051481607C0279702
Diseaseautism spectrum disorder (implicated_via_orthology)

ZNF280A MEF2B ZNF280D MEF2A MEF2C ELP2 JAKMIP1

2.02e-051521607DOID:0060041 (implicated_via_orthology)
Diseasechronic lymphocytic leukemia

ZNF280D RFX7 ORC5 ARSB SEC23IP PHLPP1

4.85e-051191606EFO_0000095
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR3

8.73e-0531602DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR3

8.73e-0531602DOID:8545 (implicated_via_orthology)
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

TRIO RFX7 ZNF292

1.01e-04171603DOID:0060307 (is_implicated_in)
DiseaseParoxysmal atrial fibrillation

USP34 RBM20 SYNE2 GNB4 MYO18B USP3

2.15e-041561606C0235480
Diseasefamilial atrial fibrillation

USP34 RBM20 SYNE2 GNB4 MYO18B USP3

2.15e-041561606C3468561
DiseasePersistent atrial fibrillation

USP34 RBM20 SYNE2 GNB4 MYO18B USP3

2.15e-041561606C2585653
DiseaseAtrial Fibrillation

USP34 RBM20 SYNE2 GNB4 MYO18B USP3

2.47e-041601606C0004238
Diseaseresponse to bevacizumab, Proteinuria

TRIO JAK1

2.89e-0451602EFO_0005943, HP_0000093
Diseaseobsolete_red blood cell distribution width

ZNF280D EP400 ZNF407 MCM6 SAMHD1 KBTBD2 PRSS36 CCNF OR2M4 TRIM33 CYFIP1 NUDT4 TRIM56 WDR20 SYNE2 PLCL2 ATP11A FBXL20

3.91e-04134716018EFO_0005192
DiseaseIntellectual Disability

IQSEC3 TRIO TMEM94 TTI2 MEF2C GTPBP2 ELP2 VPS53 ZNF292

7.81e-044471609C3714756
Diseasestachydrine measurement

ORC5 NUDT4

8.01e-0481602EFO_0021169
Diseaseatrial fibrillation

USP34 RBM20 NUDT3 SYNE2 GNB4 MYO18B USP3 ZNF292

9.86e-043711608EFO_0000275
DiseaseDystonia

SAMHD1 FASTKD2 GTPBP2 AP1S2

1.25e-03861604C0013421
Diseasesystemic lupus erythematosus (implicated_via_orthology)

TRAF3IP2 JAK1 BECN1

1.65e-03431603DOID:9074 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

TRIO MEF2C PAK1 ZNF292

1.67e-03931604C1535926
Diseasebiliary liver cirrhosis

PLCL2 FBXL20 TNPO3

1.76e-03441603EFO_0004267
Diseasepulse pressure measurement, social deprivation

FBN1 PLCL2

2.55e-03141602EFO_0005763, EFO_0009696
Diseaseinflammatory biomarker measurement, YKL40 measurement

MSH6 PHLPP1 USP3

2.69e-03511603EFO_0004869, EFO_0004872
Diseaseresponse to acetylsalicylate

SCAP KLHL18

3.34e-03161602GO_1903492
Diseaseprostate carcinoma

TRIO KCTD19 RNF213 RFX7 ZBTB42 NUDT11 PIK3C2B SYNE2 FERMT2 VPS53 MTMR9 DNAH11

3.50e-0389116012EFO_0001663
DiseaseSjogren's syndrome (implicated_via_orthology)

TRAF3IP2 CCR7

3.77e-03171602DOID:12894 (implicated_via_orthology)
Disease1-Methylhistidine measurement

OTOGL FBXL20

3.77e-03171602EFO_0021543
DiseaseMoyamoya Disease

RNF213 SAMHD1

3.77e-03171602C0026654

Protein segments in the cluster

PeptideGeneStartEntry
CKICELSFETDQVLL

ZNF280A

366

P59817
RGITLVCLNCDFLSD

ZNF280D

686

Q6N043
TLCRCGESLQDVIDR

EP400

1816

Q96L91
VLQIFCDTCEAVARL

AAK1

151

Q2M2I8
IAECLQTISDLETEC

ATG16L1

131

Q676U5
RCAIRIACIFSIQLE

ARFGEF1

981

Q9Y6D6
EQCLDVTCFSDVIRF

GVINP1

1646

Q7Z2Y8
TFIIDLCVCLFQRAR

GVINP1

2026

Q7Z2Y8
TDDGCFLELRVCSIQ

GTPBP2

446

Q9BX10
CKLEDFQEVSDLRCL

A4GNT

236

Q9UNA3
LVIFQVCLCQDEVTD

CCR7

16

P32248
LESIFVCSEDIRIQL

DNAH11

1546

Q96DT5
LQEERTCKVCLDRAV

BIRC7

246

Q96CA5
QCCIAASRIFVEESI

ALDH1A1

301

P00352
TLCNCALEELRLVFG

ELF3

101

P78545
LTVLLFLEDCIITAC

DMWD

606

Q09019
CCELDISIVDRLNSL

ATG2B

681

Q96BY7
QETCESILNCALEEL

ATP10B

946

O94823
ACLCFRSEREDEVLL

NUDT10

21

Q8NFP7
LCSEEELQLIRQACV

RCBTB2

36

O95199
CLCVTTTLDLDLAQD

RBM20

946

Q5T481
TAEELCIRAAQACRI

JAK1

56

P23458
IDREELCETVSSCFL

PCDHGA11

91

Q9Y5H2
ALLTELCQRVSFCTD

ISYNA1

431

Q9NPH2
VALIECECSEFRFIV

KCTD19

201

Q17RG1
FECEHLICQRDTILS

KASH5

296

Q8N6L0
EICRLSVLVDEFCSE

MFN1

416

Q8IWA4
FCCAIEDQDNELITL

AP1S2

66

P56377
FCLLIEQSLSLEEVC

CYFIP1

1006

Q7L576
REVSQVDTICECLLE

NUP133

691

Q8WUM0
LRIFSFLDIVTLCRC

FBXL2

21

Q9UKC9
FLCLDCQTVIRDVEQ

MCM6

156

Q14566
QLERDTILVCLDCCI

MAP4K3

781

Q8IVH8
FLEELCRILNCSETV

KCNK18

61

Q7Z418
LTDVILCVDIQEFSC

KLHL6

71

Q8WZ60
DLEEIQLVSCCLSAN

NLRC4

821

Q9NPP4
AACLCFRSEQEDEVL

NUDT4B

21

A0A024RBG1
ESLAEVVLQNCRCLD

ERVS71-1

496

P61550
ILTTACLAAQCIDRE

MTMR9

311

Q96QG7
EDCVLTAIERDFISC

LRRK1

1191

Q38SD2
CQSEILELRCTVNAL

KRT37

316

O76014
LVACNILCLLVDETA

LMBR1

311

Q8WVP7
NECVVCLSDLRDTLI

MGRN1

276

O60291
CQSEILELRCTVNAL

KRT38

316

O76015
RITFVFETLCSVNCE

ELAPOR1

496

Q6UXG2
LCEECTDTLLDQLDT

BECN1

136

Q14457
DIECVLRCSVLEIEQ

FEM1B

406

Q9UK73
LCVCSSFDQTVRVLI

DNAAF10

336

Q96MX6
FLTEAEIICDVVCLV

RHOT1

481

Q8IXI2
ETSAFERLLVICCVV

OR2M4

191

Q96R27
AACLCFRSESEEEVL

NUDT3

21

O95989
AACLCFRSEQEDEVL

NUDT4

21

Q9NZJ9
RSRICECTEAEAEII

NAV3

1786

Q8IVL0
DLTTESNLLECIRAC

POMC

36

P01189
ETACFLQVEDVLQRC

KBTBD2

106

Q8IY47
FRCSTFAELQERLEC

KIF26A

836

Q9ULI4
SVLCDCEIALIIFNS

MEF2C

36

Q06413
LSCCRFLDDSQIVTS

GNB4

146

Q9HAV0
FRVLELEVRDSICCK

JAKMIP1

596

Q96N16
VRILCEQIASDTCHL

NLRP2

716

Q9NX02
ACLCFRSEREDEVLL

NUDT11

21

Q96G61
SVLCDCEIALIIFNS

MEF2A

36

Q02078
VECIAVLDVLLCLAN

MSH6

1051

P52701
ITIAIEKEECRFCIS

FSHB

26

P01225
VCCSRLFEVTDVNKL

IQSEC3

871

Q9UPP2
ALVTFCIRDLIGCLQ

NOC2L

206

Q9Y3T9
RELVVNCCTEFIHLI

DR1

36

Q01658
SVLCDCEIALIIFNS

MEF2B

36

Q02080
SFEVCLCLLVAISTE

MAS1L

156

P35410
TVLCDRLQEALTFTC

PIK3C2B

381

O00750
LLCEQILRDTFSESC

MYO15B

1266

Q96JP2
AAAVSILTQRICDCL

PRSS36

726

Q5K4E3
IAAVCRECLQALEFL

PAK1

366

Q13153
SAIVCCIQIFSLDLV

FAM189B

191

P81408
ACDLVTLVVRACDLA

CDHR2

886

Q9BYE9
CCFDEFNRIDIEVLS

DNAH6

1521

Q9C0G6
ENVECLRFLVRLCTD

IFT88

686

Q13099
ATRVFAADCLCRIIN

HEATR5B

1246

Q9P2D3
FIRCSLQCRDLVDEA

KLHL12

241

Q53G59
FLSDRVQQDDLVRCC

KLHL18

236

O94889
ECIARTCEKLDELNI

GK2

66

Q14410
FTSLCLHLTVECVDR

CCNF

326

P41002
TGRICLDIRLETCFL

FBN1

946

P35555
SLCDDVVSVLTVLCE

ARFGEF3

201

Q5TH69
IICFLNLVIECDLET

CLLU1

26

Q5K131
TLRTIANDDCELCVN

GUCA2B

91

Q16661
ICFQLLTLCLRELFE

COQ8B

346

Q96D53
CFDELIREVTINCAE

DNALI1

131

O14645
DIQDLVSCLACLESV

IFRD2

261

Q12894
CTLIDALNVTRCALD

ARSB

181

P15848
ALTCCTVEVRTLDDR

DNAJB13

241

P59910
DLQTILCLACARDEL

EML5

196

Q05BV3
DLFLASCSQDCLIRI

ELP2

221

Q6IA86
EVRLSFICTEVDCKV

FERMT2

631

Q96AC1
LRVFRLEDSCCLFTL

SCAP

1101

Q12770
LRADAVVCLAVCAFI

S1PR5

36

Q9H228
VVCLAVCAFIVLENL

S1PR5

41

Q9H228
LAICCFVLEQSLSVR

RYR1

61

P21817
IILTAEELNCCRDAV

CPNE8

146

Q86YQ8
CSDERIDLELISFCI

KIFAP3

436

Q92845
VASLEACAVRLCELQ

LIPT2

116

A6NK58
DCSQCIDLLNRRIFI

OTOGL

1736

Q3ZCN5
ECLVCSELALLVLFS

MIB2

831

Q96AX9
EVSCSAFIRFVRLCE

FBXL21P

376

Q9UKT6
AAVVCVTLLDRLDCD

UPP2

271

O95045
QEQLKLFCETCDRLT

TRIM33

281

Q9UPN9
ECVVCLSDVRDTLIL

RNF157

276

Q96PX1
ECNICLETAREAVVS

RNF5

26

Q99942
ALVTECLEQCGRVLE

SYNE2

1521

Q8WXH0
CLDCLDRTNTVQSFI

SYNJ2

386

O15056
ISERDVLCVQIAGLC

SAMHD1

191

Q9Y3Z3
IDFCLTRTLVCDEDT

TDRD9

461

Q8NDG6
DVLTALEILCENECT

SAMD9L

651

Q8IVG5
VNCVECFTLRLLLEQ

ORC5

61

O43913
IFSFLDVVTLCRCAQ

FBXL20

36

Q96IG2
RINECDEICLSVLST

FASTKD2

261

Q9NYY8
RFQLCKELSELVSIC

PLCL2

611

Q9UPR0
LEQDLCTFLISRACK

PIK3C3

471

Q8NEB9
TTEDIRVCCQDIRVL

FTSJ3

286

Q8IY81
EAQLLTEVDTILCCQ

TEKT3

216

Q9BXF9
LTVLIFLEDCIVTAC

WDR20

536

Q8TBZ3
VCDLRFRSIIECVDD

SEC23IP

456

Q9Y6Y8
EECLFGLLTLIFLTC

SLC45A3

196

Q96JT2
LTSECLSCLVELLED

CIP2A

51

Q8TCG1
CLRTQVLEDSEDSFC

TRAF3IP2

91

O43734
RELFLEICRSCSAVL

ATP11A

781

P98196
CLESLSQCEADREAI

NLRP9

526

Q7RTR0
CRTREACEQLAIELS

RECQL5

266

O94762
DECSFVSLRDVERCV

RNF213

2631

Q63HN8
EVLVELIESRLFCRC

VWDE

196

Q8N2E2
LFFRVSAIIVCLLCE

TVP23C

41

Q96ET8
DDSLSLKVFRCLVCQ

ZFHX2

711

Q9C0A1
CLVCQAFSTDSLELL

ZFHX2

721

Q9C0A1
SSLLRTCDLEEFQTC

ELAC2

626

Q9BQ52
LNLCDASVTERLCRF

TMEM94

591

Q12767
QEATDCLILLDRCSQ

TTI2

456

Q6NXR4
AQRDTIEECLLAICN

RYR3

2461

Q15413
EVIRELICYCLDTIA

XRCC4

121

Q13426
CENVALVLERLALSC

ZNF292

96

O60281
NIDEEVISSACRLVC

RFX7

116

Q2KHR2
EDCVFIKELLRNCLS

REP15

206

Q6BDI9
LEELCLICNILSTAE

VPS53

546

Q5VIR6
VEVLIRSCLFNESFC

SLF1

506

Q9BQI6
LTCDLEDTCVLLENQ

MYO18B

1581

Q8IUG5
CRIFTELCETFLEKI

TNPO3

296

Q9Y5L0
IDSEDICSICQELLL

ZSWIM2

141

Q8NEG5
QQRELGFLCDCTVLV

ZBTB42

16

B2RXF5
TQQLCFCVLTELDVA

SLC7A6

491

Q92536
VCSLRDCLRSFTDLE

USP3

361

Q9Y6I4
SFLIQLEAFLSRLCC

ZFYVE27

151

Q5T4F4
VVTTCADCNLRIFDS

WDR76

511

Q9H967
IEVLREEACDCLFEV

XPOT

236

O43592
FREQQSLLDCILCFV

ZSWIM3

406

Q96MP5
VLHCERNQLVTLDIC

PHLPP1

856

O60346
ADCERLSAQIEECIF

TCEA2

161

Q15560
NIGLSFEECIERVCI

ZNF407

766

Q9C0G0
LLCRVAINCEKFTET

USP34

3151

Q70CQ2
ICCISEILDQAEFAD

TEX15

1986

Q9BXT5
EFIQLGSDVELICRC

WDR3

841

Q9UNX4
IANCLAVREFLCLDD

SNX16

201

P57768
CKDLFDLILTCEERV

SSU72

101

Q9NP77
SVEETCLNICRLDFS

TRIO

2996

O75962
SDFLACKICLEQLRA

TRIM56

16

Q9BRZ2
QDIFECRTCGLLESL

UBR5

1191

O95071
CSEVTEIFELSELCV

ZNF302

96

Q9NR11
FRCVTEQCATAIFLL

KCNJ1

146

P48048
SLIQDTCADLCILDI

N4BP1

101

O75113
SCVESLFLVRNFCIL

NDC1

216

Q9BTX1
FIQQCIRQLCEFLTE

NDC80

91

O14777