Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	Roundabout binding	LGR4 TGFB1I1 SLIT3	6.64e-05	12	137	3	GO:0048495
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase activity	DDR1 EPHA6 PDGFRB NTRK1 FGFR4	8.39e-05	65	137	5	GO:0004714
GeneOntologyMolecularFunction	D3 vitamins binding	CYP2R1 VDR	1.40e-04	3	137	2	GO:1902271
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	DDR1 EPHA6 PDGFRB NTRK1 FGFR4	2.98e-04	85	137	5	GO:0019199
Domain	Pkinase_Tyr	DDR1 EPHA6 PDGFRB NTRK1 TNNI3K GUCY2D TNK2 FGFR4	4.19e-06	129	134	8	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	DDR1 EPHA6 PDGFRB NTRK1 TNNI3K GUCY2D TNK2 FGFR4	6.91e-06	138	134	8	IPR001245
Domain	EGF	ATRN FRAS1 LAMA5 VWCE NRXN3 FCGBP MEGF6 VCAN SLIT3 PLAT	7.67e-06	235	134	10	SM00181
Domain	EGF-like_dom	ATRN FRAS1 LAMA5 VWCE NRXN3 FCGBP MEGF6 VCAN SLIT3 PLAT	1.27e-05	249	134	10	IPR000742
Domain	Tyr_kinase_cat_dom	DDR1 EPHA6 PDGFRB NTRK1 TNK2 FGFR4	4.08e-05	88	134	6	IPR020635
Domain	TyrKc	DDR1 EPHA6 PDGFRB NTRK1 TNK2 FGFR4	4.08e-05	88	134	6	SM00219
Domain	PROTEIN_KINASE_TYR	DDR1 EPHA6 PDGFRB NTRK1 TNK2 FGFR4	7.06e-05	97	134	6	PS00109
Domain	Tyr_kinase_AS	DDR1 EPHA6 PDGFRB NTRK1 TNK2 FGFR4	7.06e-05	97	134	6	IPR008266
Domain	Growth_fac_rcpt_	ATRN FRAS1 EPHA6 LAMA5 VWCE MEGF6 SLIT3	1.34e-04	156	134	7	IPR009030
Domain	EGF	ATRN NRXN3 MEGF6 VCAN SLIT3 PLAT	2.97e-04	126	134	6	PF00008
Domain	VWC_out	FRAS1 VWCE FCGBP	3.22e-04	19	134	3	SM00215
Domain	EGF_1	ATRN LAMA5 VWCE NRXN3 MEGF6 VCAN SLIT3 PLAT	5.13e-04	255	134	8	PS00022
Domain	EGF-like_CS	ATRN LAMA5 VWCE NRXN3 MEGF6 VCAN SLIT3 PLAT	5.98e-04	261	134	8	IPR013032
Domain	EGF_2	ATRN LAMA5 VWCE NRXN3 MEGF6 VCAN SLIT3 PLAT	6.61e-04	265	134	8	PS01186
Domain	-	TMPRSS5 SSC5D CD5L	7.40e-04	25	134	3	3.10.250.10
Domain	SRCR-like_dom	TMPRSS5 SSC5D CD5L	8.32e-04	26	134	3	IPR017448
Domain	SRCR_1	TMPRSS5 SSC5D CD5L	8.32e-04	26	134	3	PS00420
Domain	SRCR_2	TMPRSS5 SSC5D CD5L	8.32e-04	26	134	3	PS50287
Domain	IG_LIKE	CRLF1 PDGFRB NTRK1 LAIR1 SIGLEC14 SEMA3G TMEM25 ICAM5 VCAN KIR2DL5A FGFR4	8.33e-04	491	134	11	PS50835
Domain	IG	PDGFRB NTRK1 LAIR1 SIGLEC14 SEMA3G MPIG6B ICAM5 VCAN KIR2DL5A FGFR4	9.27e-04	421	134	10	SM00409
Domain	Ig_sub	PDGFRB NTRK1 LAIR1 SIGLEC14 SEMA3G MPIG6B ICAM5 VCAN KIR2DL5A FGFR4	9.27e-04	421	134	10	IPR003599
Domain	SRCR	TMPRSS5 SSC5D CD5L	9.31e-04	27	134	3	IPR001190
Domain	-	CRLF1 EPHA6 PDGFRB NTRK1 LAIR1 SIGLEC14 SEMA3G TMEM25 ICAM5 VCAN KIR2DL5A FGFR4 IL3RA	9.75e-04	663	134	13	2.60.40.10
Domain	EGF-type_Asp/Asn_hydroxyl_site	VWCE NRXN3 MEGF6 VCAN SLIT3	1.00e-03	106	134	5	IPR000152
Domain	Ig-like_dom	CRLF1 PDGFRB NTRK1 LAIR1 SIGLEC14 SEMA3G TMEM25 ICAM5 VCAN KIR2DL5A FGFR4	1.01e-03	503	134	11	IPR007110
Domain	Calx_beta	FRAS1 FREM3	1.39e-03	8	134	2	SM00237
Domain	LIM	CRIP2 MICALL1 TGFB1I1 WTIP	1.53e-03	69	134	4	PF00412
Domain	Plexin_repeat	ATRN SEMA3G SEMA5B	1.54e-03	32	134	3	IPR002165
Domain	PSI	ATRN SEMA3G SEMA5B	1.54e-03	32	134	3	PF01437
Domain	EGF_3	ATRN VWCE NRXN3 MEGF6 VCAN SLIT3 PLAT	1.55e-03	235	134	7	PS50026
Domain	-	CRIP2 MICALL1 TGFB1I1 WTIP	1.61e-03	70	134	4	2.10.110.10
Domain	LIM	CRIP2 MICALL1 TGFB1I1 WTIP	1.70e-03	71	134	4	SM00132
Domain	Znf_LIM	CRIP2 MICALL1 TGFB1I1 WTIP	1.70e-03	71	134	4	IPR001781
Domain	LIM_DOMAIN_1	CRIP2 MICALL1 TGFB1I1 WTIP	1.70e-03	71	134	4	PS00478
Domain	LIM_DOMAIN_2	CRIP2 MICALL1 TGFB1I1 WTIP	1.70e-03	71	134	4	PS50023
Domain	Ig-like_fold	CRLF1 EPHA6 PDGFRB NTRK1 LAIR1 SIGLEC14 SEMA3G TMEM25 ICAM5 VCAN KIR2DL5A FGFR4 IL3RA	1.71e-03	706	134	13	IPR013783
Domain	Calx_beta	FRAS1 FREM3	1.78e-03	9	134	2	IPR003644
Domain	Calx-beta	FRAS1 FREM3	1.78e-03	9	134	2	PF03160
Domain	EGF_Lam	ATRN LAMA5 MEGF6	2.00e-03	35	134	3	SM00180
Domain	Laminin_EGF	ATRN LAMA5 MEGF6	2.00e-03	35	134	3	PF00053
Domain	PTPc	PTPN3 PTPN6 PTPRR	2.17e-03	36	134	3	SM00194
Domain	ig	PDGFRB SIGLEC14 SEMA3G ICAM5 KIR2DL5A FGFR4	2.51e-03	190	134	6	PF00047
Domain	Immunoglobulin	PDGFRB SIGLEC14 SEMA3G ICAM5 KIR2DL5A FGFR4	2.51e-03	190	134	6	IPR013151
Domain	VWC	FRAS1 VWCE FCGBP	2.54e-03	38	134	3	SM00214
Domain	LAM_G_DOMAIN	LAMA5 NRXN3 SLIT3	2.54e-03	38	134	3	PS50025
Domain	Laminin_EGF	ATRN LAMA5 MEGF6	2.54e-03	38	134	3	IPR002049
Domain	Tyr_kinase_rcpt_2_CS	DDR1 NTRK1	2.69e-03	11	134	2	IPR002011
Domain	TYR_PHOSPHATASE_PTP	PTPN3 PTPN6 PTPRR	2.73e-03	39	134	3	PS50055
Domain	Laminin_G_2	LAMA5 NRXN3 SLIT3	2.94e-03	40	134	3	PF02210
Domain	PTPase_domain	PTPN3 PTPN6 PTPRR	3.15e-03	41	134	3	IPR000242
Domain	Y_phosphatase	PTPN3 PTPN6 PTPRR	3.15e-03	41	134	3	PF00102
Domain	RECEPTOR_TYR_KIN_II	DDR1 NTRK1	3.22e-03	12	134	2	PS00239
Domain	VWF_dom	FRAS1 VWCE FCGBP	3.38e-03	42	134	3	IPR001007
Domain	PSI	ATRN SEMA3G SEMA5B	3.86e-03	44	134	3	IPR016201
Domain	LamG	LAMA5 NRXN3 SLIT3	3.86e-03	44	134	3	SM00282
Domain	PSI	ATRN SEMA3G SEMA5B	4.38e-03	46	134	3	SM00423
Domain	-	CLSTN3 LAMA5 NRXN3 SLIT3	4.87e-03	95	134	4	2.60.120.200
Domain	EGF_Ca-bd_CS	VWCE MEGF6 VCAN SLIT3	5.25e-03	97	134	4	IPR018097
Domain	EGF_CA	VWCE MEGF6 VCAN SLIT3	5.64e-03	99	134	4	PS01187
Domain	ASX_HYDROXYL	VWCE NRXN3 MEGF6 VCAN	5.84e-03	100	134	4	PS00010
Domain	Cyt_P450_CS	CYP27C1 CYP51A1 CYP2R1	6.51e-03	53	134	3	IPR017972
Pubmed	Large-scale structural analysis of the classical human protein tyrosine phosphatome.	PDGFRB NTRK1 PTPN3 PTPN6 PTPRR TNK2	3.74e-08	47	141	6	19167335
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	LRRC8E ZXDC CRYBG2 FRAS1 ITPRIPL2 MTHFD1L KMT5C PIEZO1 KHNYN LAMA5 MUS81 ABCA7 AHDC1 PLEKHH3 DHX30 MICALL1 MEGF6 ARVCF TNK2	1.21e-07	1105	141	19	35748872
Pubmed	The protein tyrosine kinase family of the human genome.	DDR1 EPHA6 PDGFRB NTRK1 TNK2 FGFR4	1.17e-06	83	141	6	11114734
Pubmed	Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.	GALNT10 LGR4 PARP10 TNNI3K WDR6 SLIT3 VDR	2.69e-06	149	141	7	25231870
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	ATRN EPHA6 NTRK1 TMPRSS5 SEMA3G SEMA5B	8.62e-06	117	141	6	17145500
Pubmed	Signal peptide prediction based on analysis of experimentally verified cleavage sites.	CRLF1 CD177 PDGFRB INSL4 TMEM25 CD5L FGFR4 FGF19	1.31e-05	264	141	8	15340161
Pubmed	FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4.	FGFR4 FGF19	1.63e-05	2	141	2	10525310
Pubmed	Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.	KIR2DL5B KIR2DL5A	1.63e-05	2	141	2	12185535
Pubmed	Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.	KIR2DL5B KIR2DL5A	1.63e-05	2	141	2	11086080
Pubmed	Association of CYP2R1 and VDR Polymorphisms with Metabolic Syndrome Components in Non-Diabetic Brazilian Adolescents.	CYP2R1 VDR	1.63e-05	2	141	2	36364874
Pubmed	Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis.	FGFR4 FGF19	1.63e-05	2	141	2	16213224
Pubmed	Potential emerging roles of the novel adipokines adipolin/CTRP12 and meteorin-like/METRNL in obesity-osteoarthritis interplay.	METRNL C1QTNF12	1.63e-05	2	141	2	33248913
Pubmed	Selected vitamin D metabolic gene variants and risk for autism spectrum disorder in the CHARGE Study.	CYP2R1 VDR	1.63e-05	2	141	2	26073892
Pubmed	PTPH1 cooperates with vitamin D receptor to stimulate breast cancer growth through their mutual stabilization.	PTPN3 VDR	1.63e-05	2	141	2	21119599
Pubmed	Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.	KIR2DL5B KIR2DL5A	1.63e-05	2	141	2	17215859
Pubmed	Identification and characterization of leukocyte-associated Ig-like receptor-1 as a major anchor protein of tyrosine phosphatase SHP-1 in hematopoietic cells.	LAIR1 PTPN6	1.63e-05	2	141	2	10764762
Pubmed	Genetic variants of VDR and CYP2R1 affect BMI independently of serum vitamin D concentrations.	CYP2R1 VDR	1.63e-05	2	141	2	32534577
Pubmed	Vitamin D3-VDR-PTPN6 axis mediated autophagy contributes to the inhibition of macrophage foam cell formation.	PTPN6 VDR	1.63e-05	2	141	2	32917126
Pubmed	Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.	FGFR4 FGF19	1.63e-05	2	141	2	17599042
Pubmed	Up-regulation of fibroblast growth factor 19 and its receptor associates with progression from fatty liver to hepatocellular carcinoma.	FGFR4 FGF19	1.63e-05	2	141	2	27447573
Pubmed	FGFR4 provides the conduit to facilitate FGF19 signaling in breast cancer progression.	FGFR4 FGF19	1.63e-05	2	141	2	30074276
Pubmed	Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1.	DDR1 TNK2	1.63e-05	2	141	2	25427824
Pubmed	Expression of CYP2R1 and VDR in human brain pericytes: the neurovascular vitamin D autocrine/paracrine model.	CYP2R1 VDR	1.63e-05	2	141	2	25730676
Pubmed	FGF19 sustains the high proliferative ability of keratinocytes in psoriasis through the regulation of Wnt/GSK-3β/β-catenin signalling via FGFR4.	FGFR4 FGF19	1.63e-05	2	141	2	31074061
Pubmed	SNP rs12794714 of CYP2R1 is associated with serum vitamin D levels and recurrent spontaneous abortion (RSA): a case-control study.	CYP2R1 VDR	1.63e-05	2	141	2	33625596
Pubmed	FGF19 promotes epithelial-mesenchymal transition in hepatocellular carcinoma cells by modulating the GSK3β/β- catenin signaling cascade via FGFR4 activation.	FGFR4 FGF19	1.63e-05	2	141	2	26498355
Pubmed	Tripeptidyl peptidase II regulates sperm function by modulating intracellular Ca(2+) stores via the ryanodine receptor.	TPP2 RYR3	1.63e-05	2	141	2	23818952
Pubmed	Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis.	FGFR4 FGF19	1.63e-05	2	141	2	20691689
Pubmed	Fibroblast growth factor 19 is correlated with an unfavorable prognosis and promotes progression by activating fibroblast growth factor receptor 4 in advanced-stage serous ovarian cancer.	FGFR4 FGF19	1.63e-05	2	141	2	26323668
Pubmed	Association of VDR and CYP2R1 Polymorphisms with Mite-Sensitized Persistent Allergic Rhinitis in a Chinese Population.	CYP2R1 VDR	1.63e-05	2	141	2	26177022
Pubmed	FGF19 amplification reveals an oncogenic dependency upon autocrine FGF19/FGFR4 signaling in head and neck squamous cell carcinoma.	FGFR4 FGF19	1.63e-05	2	141	2	30518874
Pubmed	The ileal FGF15/19 to hepatic FGFR4 axis regulates liver regeneration after partial hepatectomy in mice.	FGFR4 FGF19	1.63e-05	2	141	2	29468415
Pubmed	FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib.	FGFR4 FGF19	1.63e-05	2	141	2	28069043
Pubmed	Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival.	FGFR4 FGF19	1.63e-05	2	141	2	27192118
Pubmed	PTPN3 suppresses lung cancer cell invasiveness by counteracting Src-mediated DAAM1 activation and actin polymerization.	PTPN3 DAAM1	1.63e-05	2	141	2	31406243
Pubmed	Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.	DDR1 PDGFRB NTRK1 FGFR4	2.11e-05	40	141	4	30898150
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ATRN GALNT10 FRAS1 CLSTN3 B4GALNT1 EDC3 ITPRIPL2 CRLF1 PIEZO1 CYP51A1 LGR4 LAMA5 ABCA7 CRIP2 FGFR4 RFT1	3.12e-05	1201	141	16	35696571
Pubmed	Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα13 Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling.	DDR1 PARD3	4.88e-05	3	141	2	26589794
Pubmed	G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2.	MPIG6B PTPN6	4.88e-05	3	141	2	11544253
Pubmed	Clostridium perfringens alpha-toxin recognizes the GM1a-TrkA complex.	B4GALNT1 NTRK1	4.88e-05	3	141	2	22847002
Pubmed	SHP-1 associates with both platelet-derived growth factor receptor and the p85 subunit of phosphatidylinositol 3-kinase.	PDGFRB PTPN6	4.88e-05	3	141	2	9452499
Pubmed	Relationship between Vitamin D3 Deficiency, Metabolic Syndrome and VDR, GC, and CYP2R1 Gene Polymorphisms.	CYP2R1 VDR	4.88e-05	3	141	2	38732523
Pubmed	Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression.	FGFR4 FGF19	4.88e-05	3	141	2	19085950
Pubmed	Development of experimental autoimmune encephalomyelitis (EAE) in mice requires vitamin D and the vitamin D receptor.	CYP2R1 VDR	4.88e-05	3	141	2	22592802
Pubmed	Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice.	FGFR4 FGF19	4.88e-05	3	141	2	19706524
Pubmed	KIR2DL5 can inhibit human NK cell activation via recruitment of Src homology region 2-containing protein tyrosine phosphatase-2 (SHP-2).	PTPN6 KIR2DL5A	4.88e-05	3	141	2	15187115
Pubmed	Alteration in the serum concentrations of FGF19, FGFR4 and βKlotho in patients with thyroid cancer.	FGFR4 FGF19	4.88e-05	3	141	2	29438906
Pubmed	FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action.	FGFR4 FGF19	4.88e-05	3	141	2	19237543
Pubmed	Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice.	PDGFRB PTPN6	4.88e-05	3	141	2	8245788
Pubmed	Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.	DDR1 PARD3	4.88e-05	3	141	2	21170030
Pubmed	25-Hydroxyvitamin D Serum Levels Linked to Single Nucleotide Polymorphisms (SNPs) (rs2228570, rs2282679, rs10741657) in Skeletal Muscle Aging in Institutionalized Elderly Men Not Supplemented with Vitamin D.	CYP2R1 VDR	4.88e-05	3	141	2	36233147
Pubmed	Liver-specific activities of FGF19 require Klotho beta.	FGFR4 FGF19	4.88e-05	3	141	2	17627937
Pubmed	Phosphorylation of NTRK1 at Y674/Y675 induced by TP53-dependent repression of PTPN6 expression: a potential novel prognostic marker for breast cancer.	NTRK1 PTPN6	4.88e-05	3	141	2	23948750
Pubmed	Sulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlotho.	FGFR4 FGF19	4.88e-05	3	141	2	21653700
Pubmed	Association of Single Nucleotide Polymorphism in VDR, GC Globulin and CYP2R1 with the Risk of Esophageal Cancer.	CYP2R1 VDR	4.88e-05	3	141	2	37898838
Pubmed	Gene expression profiling of vitamin D metabolism enzymes in leukemia and lymphoma patients: molecular aspect interplay of VDR, CYP2R1, and CYP24A1.	CYP2R1 VDR	4.88e-05	3	141	2	38632160
Pubmed	A rare haplotype of the vitamin D receptor gene is protective against diabetic nephropathy.	CYP2R1 VDR	4.88e-05	3	141	2	19783860
Pubmed	Vitamin D deficiency associates with susceptibility to tuberculosis in Pakistan, but polymorphisms in VDR, DBP and CYP2R1 do not.	CYP2R1 VDR	4.88e-05	3	141	2	27160686
Pubmed	Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.	SIRT5 MLYCD	4.88e-05	3	141	2	30726738
Pubmed	Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity.	FGFR4 FGF19	4.88e-05	3	141	2	25056539
Pubmed	Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function.	MPIG6B PTPN6	4.88e-05	3	141	2	23509158
Pubmed	FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways.	FGFR4 FGF19	4.88e-05	3	141	2	21437243
Pubmed	FGF19-induced hepatocyte proliferation is mediated through FGFR4 activation.	FGFR4 FGF19	4.88e-05	3	141	2	20018895
Pubmed	Integrative role of vitamin D related and Interleukin-28B genes polymorphism in predicting treatment outcomes of Chronic Hepatitis C.	CYP2R1 VDR	4.88e-05	3	141	2	26911666
Pubmed	Expression profile of receptor-type protein tyrosine kinase genes in the human thyroid.	DDR1 PDGFRB	4.88e-05	3	141	2	9492013
Pubmed	Enhanced autocrine FGF19/FGFR4 signaling drives the progression of lung squamous cell carcinoma, which responds to mTOR inhibitor AZD2104.	FGFR4 FGF19	4.88e-05	3	141	2	32111983
Pubmed	Fibroblast Growth Factor 19-Mediated Up-regulation of SYR-Related High-Mobility Group Box 18 Promotes Hepatocellular Carcinoma Metastasis by Transactivating Fibroblast Growth Factor Receptor 4 and Fms-Related Tyrosine Kinase 4.	FGFR4 FGF19	4.88e-05	3	141	2	31529503
Pubmed	Promoter variants of KIR2DL5 add to diversity and may impact gene expression.	KIR2DL5B KIR2DL5A	4.88e-05	3	141	2	18461314
Pubmed	Frequent methylation of the KLOTHO gene and overexpression of the FGFR4 receptor in invasive ductal carcinoma of the breast.	FGFR4 FGF19	4.88e-05	3	141	2	26152288
Pubmed	Repression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferation.	NTRK1 PTPN6	4.88e-05	3	141	2	19749791
Pubmed	Genetic variants in CYP2R1, CYP24A1, and VDR modify the efficacy of vitamin D3 supplementation for increasing serum 25-hydroxyvitamin D levels in a randomized controlled trial.	CYP2R1 VDR	4.88e-05	3	141	2	25070320
Pubmed	The functional polymorphisms of VDR, GC and CYP2R1 are involved in the pathogenesis of autoimmune thyroid diseases.	CYP2R1 VDR	4.88e-05	3	141	2	25046415
Pubmed	Expression of Fraser syndrome genes in normal and polycystic murine kidneys.	FRAS1 FREM3	4.88e-05	3	141	2	21993971
Pubmed	Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.	MPIG6B PTPN6	4.88e-05	3	141	2	29891536
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FRAS1 LAMA5 FREM3	5.09e-05	18	141	3	14730302
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	FRAS1 PDGFRB LAMA5 MMP21 SLIT3	5.64e-05	100	141	5	25807483
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	FRAS1 ZSWIM5 KANK2 SEMA5B POLR3E	6.49e-05	103	141	5	10819331
Pubmed	FGF19 Protects Hepatocellular Carcinoma Cells against Endoplasmic Reticulum Stress via Activation of FGFR4-GSK3β-Nrf2 Signaling.	FGFR4 FGF19	9.74e-05	4	141	2	28951455
Pubmed	The ITIM-containing receptor LAIR1 is essential for acute myeloid leukaemia development.	LAIR1 PTPN6	9.74e-05	4	141	2	25915125
Pubmed	Vitamin D pathway gene polymorphisms, vitamin D level, and cytokines in children with type 1 diabetes.	CYP2R1 VDR	9.74e-05	4	141	2	33961971
Pubmed	Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.	KIR2DL5B KIR2DL5A	9.74e-05	4	141	2	22652695
Pubmed	FGF19 and FGFR4 promotes the progression of gallbladder carcinoma in an autocrine pathway dependent on GPBAR1-cAMP-EGR1 axis.	FGFR4 FGF19	9.74e-05	4	141	2	34163030
Pubmed	Selection of High-Quality Spermatozoa May Be Promoted by Activated Vitamin D in the Woman.	CYP2R1 VDR	9.74e-05	4	141	2	27977320
Pubmed	Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.	FRAS1 FREM3	9.74e-05	4	141	2	18563433
Pubmed	FGF19-mediated ELF4 overexpression promotes colorectal cancer metastasis through transactivating FGFR4 and SRC.	FGFR4 FGF19	9.74e-05	4	141	2	36923538
Pubmed	Genetic Variation in CYP2R1 and GC Genes Associated With Vitamin D Deficiency Status.	CYP2R1 VDR	9.74e-05	4	141	2	26038244
Pubmed	PDGFR-β-activated ACK1-AKT signaling promotes glioma tumorigenesis.	PDGFRB TNK2	9.74e-05	4	141	2	25257795
Pubmed	LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes.	LAIR1 PTPN6	9.74e-05	4	141	2	9285412
Pubmed	FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway.	FGFR4 FGF19	9.74e-05	4	141	2	21641554
Pubmed	KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.	KIR2DL5B KIR2DL5A	9.74e-05	4	141	2	10820258
Pubmed	Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.	FRAS1 FREM3	9.74e-05	4	141	2	24101214
Pubmed	DNA hypermethylation of tumor suppressor genes TWIST1, GATA4, MUS81 and NTRK1 in endometrial hyperplasia.	NTRK1 MUS81	9.74e-05	4	141	2	39242200
Pubmed	PTPH1 is a predominant protein-tyrosine phosphatase capable of interacting with and dephosphorylating the T cell receptor zeta subunit.	PTPN3 PTPN6	9.74e-05	4	141	2	14672952
Pubmed	Characterization of multiple sclerosis traits: nuclear receptors (NR) impaired apoptosis pathway and the role of 1-α 25-dihydroxyvitamin D3.	NR4A1 VDR	9.74e-05	4	141	2	21752397
Pubmed	Ancestry-Adjusted Vitamin D Metabolite Concentrations in Association With Cytochrome P450 3A Polymorphisms.	CYP2R1 VDR	9.74e-05	4	141	2	28673024
Pubmed	A role for the tyrosine kinase ACK1 in neurotrophin signaling and neuronal extension and branching.	NTRK1 TNK2	9.74e-05	4	141	2	23598414
Pubmed	Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.	KIR2DL5B KIR2DL5A	9.74e-05	4	141	2	18498296
Pubmed	Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.	RASGRP4 PDGFRB LAMA5 NR4A1 PTPRR FGFR4 DAAM1 PARD3	1.44e-04	371	141	8	25241761
Pubmed	TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis.	NTRK1 PTPN6	1.62e-04	5	141	2	29715200
Pubmed	Polymorphisms in vitamin D metabolism related genes and risk of multiple sclerosis.	CYP2R1 VDR	1.62e-04	5	141	2	20007432
Interaction	SLURP1 interactions	ATRN CRLF1 DSC2 METRNL LAMA5 ICAM5 VCAN PLAT	6.43e-06	144	137	8	int:SLURP1
Interaction	LY86 interactions	ATRN CLSTN3 CRLF1 LONP2 METRNL LAMA5 ICAM5 VCAN FGFR4	1.79e-05	217	137	9	int:LY86
Interaction	NCR3 interactions	ATRN GALNT10 FRAS1 METRNL LAMA5 VCAN FGFR4	1.81e-05	120	137	7	int:NCR3
Interaction	IL5RA interactions	FRAS1 B4GALNT1 DSC2 METRNL LAMA5 ICAM5 FGFR4	2.23e-05	124	137	7	int:IL5RA
Interaction	EPHA7 interactions	ATRN CRLF1 DSC2 METRNL LAMA5 SEPTIN6 CYFIP2 WDR6 FGFR4 PARD3	2.36e-05	282	137	10	int:EPHA7
Interaction	PRG2 interactions	FRAS1 CLSTN3 B4GALNT1 CRLF1 DSC2 METRNL LAMA5 ICAM5 VCAN FGFR4	2.58e-05	285	137	10	int:PRG2
Interaction	CBLN4 interactions	FRAS1 CLSTN3 CRLF1 METRNL LAMA5 NRXN3 FGFR4	2.61e-05	127	137	7	int:CBLN4
Interaction	GGH interactions	ATRN FRAS1 CRLF1 METRNL NTRK1 LAMA5 ICAM5 VCAN FGFR4	4.36e-05	243	137	9	int:GGH
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	DDR1 PDGFRB NTRK1 FGFR4	2.88e-05	40	80	4	321
GeneFamily	LIM domain containing	CRIP2 MICALL1 TGFB1I1 WTIP	1.34e-04	59	80	4	1218
GeneFamily	Immunoglobulin like domain containing	PDGFRB NTRK1 LAIR1 SEMA3G ICAM5	1.66e-03	193	80	5	594
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	DDR1 CD177 PDGFRB LAIR1 KIR2DL5A FGFR4 IL3RA	1.79e-03	394	80	7	471
GeneFamily	Protein tyrosine phosphatases, non-receptor type	PTPN3 PTPN6	2.83e-03	18	80	2	812
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL5B KIR2DL5A	2.83e-03	18	80	2	620
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA3G SEMA5B	3.49e-03	20	80	2	736
Coexpression	PEREZ_TP53_TARGETS	LRRC8E ZXDC ABHD15 GALNT10 CRYBG2 ITPRIPL2 LONP2 METRNL CYP27C1 GPR143 TYSND1 VWCE ABCA7 AHDC1 CRIP2 CYFIP2 BICDL1 MEGF6 VCAN HAGH C1QTNF12 WIPI2 VDR	8.78e-08	1201	139	23	M4391
Coexpression	GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP	DDR1 CRYBG2 PDGFRB MTHFD1L CYP51A1 HMBS SEPTIN6 TNK2 C1QTNF12	1.28e-06	200	139	9	M5680
Coexpression	DESCARTES_FETAL_THYMUS_THYMIC_EPITHELIAL_CELLS	FRAS1 EPHA6 DSC2 PITRM1 PLEKHH3 PTPN3 NRXN3 SLIT3 SEZ6L	6.49e-06	244	139	9	M40312
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 B4GALNT1 METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	6.28e-08	168	140	8	c0aef5947b1d7e2c81a7481c509feda1687fcd7f
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 B4GALNT1 METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2	7.62e-07	160	140	7	bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	8.99e-07	164	140	7	15d52666e5150e7c34b1f641a937fb2d5e8aaf8a
ToppCell	facs-Lung-EPCAM-24m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	8.99e-07	164	140	7	d622f0d8d8bad48dfdf160ec63c545df192637a9
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.06e-06	168	140	7	c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK3 LAIR1 SEMA3G CYFIP2 PTPN6 SLIT3 WIPI2	1.10e-06	169	140	7	15a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLSTN3 CRLF1 KRT84 SSC5D TMEM179 FGFR4 TRMT61A	2.16e-06	187	140	7	69b47f00598d647e2a99427ebddf42c339428e47
ToppCell	RA\|World / Chamber and Cluster_Paper	FRAS1 MTHFD1L LGR4 NR4A1 VCAN SLIT3 DAAM1	2.75e-06	194	140	7	08f0afbb68a63150fbe107a5337299081c3f69e4
ToppCell	facs-Skin-Telogen-3m-Epithelial-outer_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 LDLRAD3 ARVCF SLIT3 PLAT C1QTNF12 VDR	2.95e-06	196	140	7	c936014125b2ed5f796221b74acb77b8f8359875
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	B4GALNT1 CRLF1 PDGFRB NR4A1 KANK2 TGFB1I1 SLIT3	2.95e-06	196	140	7	ac4c8571bd792538f8df7b9bdd90ef58405fd3b1
ToppCell	Kidney-Mesangial\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	PDGFRB KANK2 CRIP2 PLEKHH3 TGFB1I1 WTIP SLIT3	2.95e-06	196	140	7	2b2cbe7f96213b7ff50442593f31820d17a2ae94
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	B4GALNT1 CRLF1 PDGFRB NR4A1 KANK2 TGFB1I1 SLIT3	2.95e-06	196	140	7	70b2e0b4ff4f1bc03fb72ace07a8a44f4b415922
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	DDR1 FRAS1 DSC2 CD177 LGR4 LAMA5 CRIP2	3.05e-06	197	140	7	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	(4)_Endothelial_cells-(41)_EC-arteriolar\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	DDAH2 SLCO3A1 SEMA3G CRIP2 TGFB1I1 PTPRR PLAT	3.05e-06	197	140	7	482e3f8926880afed88ed37553ed2b5ed58b8c99
ToppCell	droplet-Lung-nan-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	9.04e-06	153	140	6	6dcab3d50ab50051955204dc4e4a64c1ca855bcd
ToppCell	droplet-Lung-nan-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	9.04e-06	153	140	6	f6ef14d949107c08cb3690e26ec91e194cb43518
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B4GALNT1 METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2	1.09e-05	158	140	6	121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3G VWCE NRXN3 MEGF6 GUCY2D UFSP1	1.09e-05	158	140	6	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA3G VWCE NRXN3 MEGF6 GUCY2D UFSP1	1.09e-05	158	140	6	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	343B-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	LRRC8E WDR7 SIGLEC14 NR4A1 WTIP VCAN	1.09e-05	158	140	6	de65af8d3b8514b17978155f31975e2347b75251
ToppCell	facs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 B4GALNT1 METRNL LAIR1 NR4A1 CYFIP2	1.25e-05	162	140	6	484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 B4GALNT1 METRNL LAIR1 NR4A1 CYFIP2	1.25e-05	162	140	6	bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.30e-05	163	140	6	bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACAT2 KHNYN RYR3 DHX30 FAN1 KLHL42	1.30e-05	163	140	6	d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell	facs-Marrow-T-cells-24m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF1 KRT84 HMBS ISG20 CRIP2 HAGH	1.30e-05	163	140	6	c1e9c3b05d407b4dff1cd53de688b43b61128ad0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB SLCO3A1 LDLRAD3 SEMA5B PTPRR SLIT3	1.34e-05	164	140	6	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.34e-05	164	140	6	11dfd84f5fb90de330858e1e852848832734e004
ToppCell	droplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.44e-05	166	140	6	1a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA6 NTRK1 RYR3 ITPKA TNNI3K ICAM5	1.49e-05	167	140	6	3dfec2fcc36caa6e394efae5e540a6fa28759977
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA6 NTRK1 RYR3 ITPKA TNNI3K ICAM5	1.49e-05	167	140	6	95b3b5ba3414729f0460a26a0deca48de0cbe33e
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA6 NTRK1 RYR3 ITPKA TNNI3K ICAM5	1.49e-05	167	140	6	9480739587d51e67a281778b9bddd7b5ffc3ad92
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.54e-05	168	140	6	4b5be7c6662eceddf90a65015f12908278d1664e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.54e-05	168	140	6	689c41f6e9f65381570991cc311cba49a57ec955
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRB KANK2 VCAN SLIT3 FGFR4 FGF19	1.64e-05	170	140	6	b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.70e-05	171	140	6	00739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCell	droplet-Lung-nan-21m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.76e-05	172	140	6	51bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCell	AT1-AT2_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CRYBG2 LAMA5 KANK2 CRIP2 PLEKHH3 PTPRR	1.76e-05	172	140	6	0be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCell	droplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.76e-05	172	140	6	5f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCell	droplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.76e-05	172	140	6	be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCell	ASK440-Epithelial-Transformed_epithelium\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	PDGFRB BRME1 KLHL35 MPIG6B TMEM25 SLIT3	1.76e-05	172	140	6	df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCell	droplet-Lung-LUNG-1m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.94e-05	175	140	6	c8cfe0ac0c1ac447c626a623cc49692a0b177a1c
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	METRNL LAIR1 NR4A1 LDLRAD3 CYFIP2 PTPN6	1.94e-05	175	140	6	61fbd8f685d3daad46449e4c0386a38886496566
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CRLF1 EPHA6 FREM3 CRIP2 ITPKA SLIT3	2.00e-05	176	140	6	212e643c50c68462d4b016428ab30eeb7868ef40
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CRLF1 CRIP2 ITPKA SEMA5B ICAM5 SLIT3	2.00e-05	176	140	6	c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN RASGRP4 AMPD3 HK3 CD177 MOCOS	2.07e-05	177	140	6	065bebd22031f143e90a407f952b444a3f8818c7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CRLF1 EPHA6 CRIP2 ITPKA SEMA5B SLIT3	2.07e-05	177	140	6	8b003ed7887479c3a010ef37dd981b748256bda7
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	B4GALNT1 PDGFRB NR4A1 KANK2 PLEKHH3 TGFB1I1	2.07e-05	177	140	6	452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell	facs-Marrow-Granulocytes-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRN RASGRP4 AMPD3 HK3 CD177 MOCOS	2.07e-05	177	140	6	eb304f20aab075bd17aa3aef819386c0e1a235bd
ToppCell	ASK440-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	PDGFRB BRME1 KLHL35 MPIG6B TMEM25 SLIT3	2.13e-05	178	140	6	86f1741636ed3e85bb4a65f84949b718fc38c290
ToppCell	AT1_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	CRYBG2 LAMA5 KANK2 ABCA7 CRIP2 WTIP	2.27e-05	180	140	6	ff4728782c3ec814ba071cc22b7894abdd9da837
ToppCell	HSPCs-Erythroblasts\|HSPCs / Lineage and Cell class	AMPD3 HMBS ISG20 CRIP2 HAGH C1QTNF12	2.34e-05	181	140	6	4ded490f190af7ace343acdf317edc7373484d08
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT10 CYP27C1 LGR4 SLCO3A1 PTPN3 VDR	2.34e-05	181	140	6	22363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCell	10x5'v1-week_12-13-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GALNT10 AMPD3 CRYBG2 HK3 CD177 ABCA7	2.42e-05	182	140	6	52eac2f892ea7f26731e0b21c578fd2665a1657a
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response-SM_activated_stress_response_L.2.3.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	B4GALNT1 PDGFRB NR4A1 KANK2 TGFB1I1 SLIT3	2.42e-05	182	140	6	97bb07478f56a937b490fba121ee603db64134a1
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-SM_activated_stress_response\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	B4GALNT1 PDGFRB NR4A1 KANK2 TGFB1I1 SLIT3	2.42e-05	182	140	6	1c1a687f728341c209b048b6715bcddd0ac20069
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 SLCO3A1 NRXN3 VCAN SLIT3 PARD3	2.49e-05	183	140	6	07ca2786e62eca9feecf5e54a11864a960f7641a
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CRLF1 EPHA6 FREM3 ITPKA SEMA5B SLIT3	2.57e-05	184	140	6	34e316ad8e7b8667cd8ad61397281802a252744f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB SLCO3A1 LDLRAD3 KANK2 NRXN3 SLIT3	2.65e-05	185	140	6	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD15 B4GALNT1 LAIR1 LDLRAD3 SEPTIN6 SCART1	2.65e-05	185	140	6	7d6954bb04368ec62b284ba6c3021a15fbdfdee6
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB SLCO3A1 LDLRAD3 KANK2 NRXN3 SLIT3	2.65e-05	185	140	6	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-bladder_mesenchymal_cell_(Scara5+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 AMPD3 METRNL NTRK1 NR4A1 SLIT3	2.81e-05	187	140	6	7beba2a5d5978f2ae7d8bde10815705cf2572211
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PDGFRB CRIP2 PLEKHH3 MEGF6 SEMA5B SLIT3	2.81e-05	187	140	6	1aebf6fab40b96f2f5feb77a302bb805838fccf3
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT10 AMPD3 SEMA5B TMEM179 VCAN SEZ6L	2.90e-05	188	140	6	7471c194276161422326647f09022e94f3d1640c
ToppCell	droplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH2 LAMA5 SEMA3G CRIP2 PTPRR PLAT	2.90e-05	188	140	6	405efea75233ecf70f7d19b630230798d817b7f2
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT10 AMPD3 SEMA5B TMEM179 VCAN SEZ6L	2.90e-05	188	140	6	053c251d3ddbeb866f34565aefca4535517b4387
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 LDLRAD3 NRXN3 VCAN SLIT3 SEZ6L	2.90e-05	188	140	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	facs-Heart-RA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSC2 CD177 NR4A1 RYR3 ITPKA TNNI3K	2.99e-05	189	140	6	e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 EPHA6 LGR4 PTPN3 BICDL1 FCGBP	3.08e-05	190	140	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CRLF1 PDGFRB KANK2 TGFB1I1 SEMA5B SLIT3	3.08e-05	190	140	6	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT10 AMPD3 SEMA5B TMEM179 VCAN SEZ6L	3.17e-05	191	140	6	ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT10 AMPD3 SEMA5B TMEM179 VCAN SEZ6L	3.17e-05	191	140	6	478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDAH2 METRNL SLCO3A1 VCAN SLIT3 PLAT	3.26e-05	192	140	6	30cefa0990ba1f379f350bfbf994a78db145075e
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PDGFRB CRIP2 TGFB1I1 MEGF6 SEMA5B SLIT3	3.26e-05	192	140	6	a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	FRAS1 ZSWIM5 LGR4 NRXN3 DAAM1 PARD3	3.36e-05	193	140	6	503a979328c68b096680b71359a26f02fafdff35
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 LGR4 CYFIP2 PTPN3 BICDL1 PARD3	3.36e-05	193	140	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 LDLRAD3 CRIP2 RYR3 PLAT IL3RA	3.36e-05	193	140	6	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PDGFRB NTRK1 CYP27C1 SSC5D VCAN SLIT3	3.36e-05	193	140	6	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PDGFRB CRIP2 TGFB1I1 MEGF6 SEMA5B SLIT3	3.36e-05	193	140	6	ba6eb29478d16589172f48f9992e5116328c81d6
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF1 PDGFRB LAMA5 KANK2 TGFB1I1 WTIP	3.46e-05	194	140	6	bf34737ae2dc218f890fbb9201c308b324415749
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 LGR4 PTPN3 BICDL1 MCU PARD3	3.46e-05	194	140	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	15-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	CRIP2 TGFB1I1 MEGF6 SEMA5B SLIT3 PLAT	3.46e-05	194	140	6	5c1218d239c88082496924653ed2a092dc44a906
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.46e-05	194	140	6	5099e6ad7c19e5f8b73449d904aaefd97f1b1959
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.46e-05	194	140	6	71734ef7b34ab33b349595368176fa0e1175d4d0
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF1 PDGFRB LAMA5 KANK2 TGFB1I1 WTIP	3.46e-05	194	140	6	b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB LDLRAD3 KANK2 WTIP VCAN SLIT3	3.46e-05	194	140	6	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRLF1 PDGFRB LAMA5 KANK2 TGFB1I1 WTIP	3.46e-05	194	140	6	4ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 LGR4 CYFIP2 PTPN3 BICDL1 PARD3	3.56e-05	195	140	6	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 LDLRAD3 ARVCF SLIT3 PLAT C1QTNF12	3.66e-05	196	140	6	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PDGFRB CRIP2 TGFB1I1 MEGF6 SEMA5B SLIT3	3.66e-05	196	140	6	40cae477b3906623d1f2a4c630279e710499ce80
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-1\|TCGA-Stomach / Sample_Type by Project: Shred V9	BRME1 KLHL35 MEGF6 ICAM5 PNMA6A	3.73e-05	119	140	5	5d5fcddb5723e7a94bfcf56e165a980fa450b789
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PDGFRB CRIP2 TGFB1I1 SEMA5B WTIP SLIT3	3.76e-05	197	140	6	4d63a274828ebb951db78421c2823453d862cd49
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.76e-05	197	140	6	8b3bf5b45e49bf1c60e4d2703b470bb890385f67
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.76e-05	197	140	6	02e70768a917c5f097bc653e9e965a1000289d2e
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.76e-05	197	140	6	aafe279b14cdcb786bc45524bc3c26261128ee48
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.76e-05	197	140	6	fb14da600f563273059a4683a5079af81aca0886
ToppCell	Bronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PDGFRB MMP21 TGFB1I1 SEMA5B WTIP SLIT3	3.76e-05	197	140	6	d1cb30ec4f3024541e9876c70bf63fe4d5c55bf1
ToppCell	cellseq2-Immune-Immune_Myeloid-iMON-iMON\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RASGRP4 CPPED1 HK3 LAIR1 SIGLEC14 VCAN	3.87e-05	198	140	6	a6aa113f0af4d25c032f440c3134fe4d88ca5055
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.87e-05	198	140	6	77288df94286382170a266474ab85960519e8449
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB KANK2 CRIP2 TGFB1I1 WTIP SLIT3	3.87e-05	198	140	6	2ee195f20a4f91fa1dcad9eaf96d6086e3b0fb4a
ToppCell	cellseq2-Immune-Immune_Myeloid-iMON\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	RASGRP4 CPPED1 HK3 LAIR1 SIGLEC14 VCAN	3.87e-05	198	140	6	a0ceed8689d42be6b9cde89d6c182d10b3fb14fc
Drug	GW 4064	ABHD15 WDR7 PDGFRB ACAT2 VWCE MEGF6 SEMA5B PTPRR ICAM5 TMEM179 PLAT FGFR4 FGF19	2.77e-06	438	138	13	ctd:C412815
Disease	autism spectrum disorder (implicated_via_orthology)	PDGFRB KMT5C NRXN3 ARVCF MOCOS	5.80e-04	152	130	5	DOID:0060041 (implicated_via_orthology)
Disease	fear of medical pain measurement	WDR18 TNNI3K	8.47e-04	10	130	2	EFO_0008339
Disease	Posterior Choroidal Artery Infarction	PLAT VDR	1.03e-03	11	130	2	C0887799
Disease	Cerebral Infarction, Left Hemisphere	PLAT VDR	1.03e-03	11	130	2	C0751010
Disease	Anterior Choroidal Artery Infarction	PLAT VDR	1.03e-03	11	130	2	C0751012
Disease	Cerebral Infarction, Right Hemisphere	PLAT VDR	1.03e-03	11	130	2	C0751011
Disease	Subcortical Infarction	PLAT VDR	1.03e-03	11	130	2	C0751014
Disease	Cerebral Infarction	PLAT VDR	1.03e-03	11	130	2	C0007785
Disease	triacylglycerol 58:12 measurement	NRXN3 WTIP	1.24e-03	12	130	2	EFO_0010439
Disease	skin melanoma (is_implicated_in)	DDR1 VDR	1.69e-03	14	130	2	DOID:8923 (is_implicated_in)
Disease	response to lithium ion	NRXN3 MEGF6 SLIT3	1.95e-03	56	130	3	GO_0010226
Disease	pursuit maintenance gain measurement	ZXDC TMPRSS5 MLYCD EPG5	2.18e-03	123	130	4	EFO_0008433
Disease	glaucoma (implicated_via_orthology)	NTRK1 LGR4	2.51e-03	17	130	2	DOID:1686 (implicated_via_orthology)
Disease	Disorder of eye	FRAS1 GPR143 VCAN GUCY2D CLRN1	2.53e-03	212	130	5	C0015397

Protein segments in the cluster

Peptide	Gene	Start	Entry
PRICGVCGDRATGFH	VDR	21	P11473
IDGCIGRRFFQSPAH	EPG5	1331	Q9HCE0
CLVGGYRVHGDAPLA	DPEP2NB	56	A0A0U1RQF7
FGHGVRSCIGRRIAE	CYP27C1	481	Q4G0S4
GALDRHFLLRGGGPV	ARVCF	161	O00192
CGFRLHGSGVPFEAV	CLSTN3	66	Q9BQT9
HPVTVARAQCGGGLL	VCAN	306	P13611
RRGFHHELVGFPGCV	B4GALNT1	416	Q00973
HTLGARLPGGVECRF	DDR1	291	Q08345
QPVRLCCGRAERGGH	FGFR4	51	P22455
GLRLVGEAFHCRLQG	C1QTNF12	146	Q5T7M4
PHRCLFSRGITALDG	APRG1	106	Q8IVJ8
PSGVRLVGGLHRCEG	CD5L	21	O43866
THCYDGLLRLRGGGI	CD177	156	Q8N6Q3
SGVHLDCGGLRLSRP	AHDC1	141	Q5TGY3
EPLSVGIHACRRGGV	SORD	156	Q00796
HIDARGEPGGILCFL	DHX30	661	Q7L2E3
LCRGHSAGRGDEPSI	BICDL1	546	Q6ZP65
GCGSPRIHFGGLIEE	MTHFD1L	301	Q6UB35
DCTHRVDPRIGGGGV	DSC2	676	Q02487
GRFRCLGSPQHLKGR	ABCA7	2001	Q8IZY2
SRHGGHCGFLRQEPL	ABHD15	386	Q6UXT9
AIDFCPGVIRRHHGG	CHRNE	206	Q04844
EQLFGLGLRPRGECH	TNK2	996	Q07912
RGLSTFLFRPHCGEA	AMPD3	576	Q01432
HGEGALRVLLRGFAP	C17orf113	536	A0A1B0GUU1
SRDAALFPGCERGLH	RBFA	21	Q8N0V3
PARLAHIAVGAFCLG	RFT1	496	Q96AA3
GLGPHRESGLARCSL	ISG20	16	Q96AZ6
EPVLVHCSAGIGRTG	PTPN3	836	P26045
RGGHVTLLCRSRLGF	KIR2DL5A	41	Q8N109
SGLVLHRLQCARGFG	NR4A1	466	P22736
HIVRFFGVCTEGRPL	NTRK1	571	P04629
AAVGSRPIHCGVRFG	KRT84	66	Q9NSB2
FPCASGIHCIIGRFR	LDLRAD3	76	Q86YD5
ALRQGHCLPRCGEGF	FRAS1	631	Q86XX4
TLGREFHRIALGGVC	LONP2	391	Q86WA8
AGCFPGLGVSRHRQQ	MCU	31	Q8NE86
RIGLHSGPCVAGVVG	GUCY2D	976	Q02846
GCGPHCRLRGEALVA	KMT5C	361	Q86Y97
HGALGSPLRLEGCVR	GALNT10	476	Q86SR1
ARRGLGPALLGVFCH	HAGH	21	Q16775
HRSEAACLAAGPGIR	ATRN	651	O75882
LGSHVTFVCRGPVGV	LAIR1	41	Q6GTX8
ELLGRLARGFGVDHG	MLYCD	86	O95822
RGGHVTLLCRSRLGF	KIR2DL5B	41	Q8NHK3
FSCRAELDLRPHGLG	ICAM5	196	Q9UMF0
IKLGFGRGRHLGCPR	MMP21	226	Q8N119
GPHGLSSCFLRIRAD	FGF19	51	O95750
LGQIVDRCRNGPGFH	FUBP3	141	Q96I24
AGCAGFRLPVLGVHL	RASGRP4	341	Q8TDF6
LHRSGQIERGCEGPS	NRXN3	1036	Q9Y4C0
HGIGPACDLRFRSIV	DDHD2	221	O94830
LGATVAGCFPLFHRG	LGR4	671	Q9BXB1
EHCARLGPGTRSGTR	MICALL1	216	Q8N3F8
SIGSLRFQVLGPCHR	MOCOS	796	Q96EN8
ACGLERIPHAVFSLG	LRRC8E	591	Q6NSJ5
TLLECGVRPGHGDFL	METRNL	256	Q641Q3
PLGEHAGRIYLCDIG	EDC3	466	Q96F86
PLTGACRGCLRHTTG	LAMA5	1986	O15230
GFSGCVKRLRLHGRP	LAMA5	3486	O15230
LFHPTGGTQGRRGCR	CYFIP2	566	Q96F07
AELRGCGPRFGKHLL	INSL4	26	Q14641
GGRVCERHPRFCSVL	HK3	426	P52790
GNQRISGVCIHPRFG	MMACHC	141	Q9Y4U1
PGHRLLLVGGCETAE	NBAS	246	A2RRP1
PGNLHGAFRGLRTDC	MCIDAS	316	D6RGH6
ALRGCVPAFHGVVER	ITPKA	226	P23677
RGPVVVHCSAGIGRT	PTPRR	581	Q15256
HELSRRAVCASIPGG	DAAM1	516	Q9Y4D1
HILVRGRSAAFGIPC	IL3RA	181	P26951
ADGGHRRALPGCTSL	BRME1	376	Q0VDD7
ARGCHSNGTFGRLPR	CARD6	806	Q9BX69
TCGTRPGLHRFAVLQ	FCGBP	1281	Q9Y6R7
QTCGTRPGLHRFAVL	FCGBP	2481	Q9Y6R7
AQTCGTRPGLHRFAV	FCGBP	3681	Q9Y6R7
EALVPFSLGRRHCLG	CYP2R1	436	Q6VVX0
CSSFRLRGLHGPATG	CPHXL2	376	A0A1W2PPK0
ELGRHGIRCNSVLPG	HSD17B8	186	Q92506
PRAFHALCLGSGGLR	GPR143	26	P51810
DGCLGIGRGSLRHSL	INTS14	116	Q96SY0
CGSRDRGVSGRPHLA	DMRTA1	6	Q5VZB9
VPFGAGRHRCIGENF	CYP51A1	446	Q16850
PHLASVGSLRVLGGC	CRYBG2	1201	Q8N1P7
AIGCQLGRDPHGLRV	CPPED1	266	Q9BRF8
LDTPGASCGIGRRHG	LYG1	31	Q8N1E2
LGHPTAGRGRSELCL	KANK2	236	Q63ZY3
EIALGGGGFCVHREP	KHNYN	311	O15037
LRCERCGKTLTPGGH	CRIP2	151	P52943
RAFLRHLEGGCSVPV	HMBS	251	P08397
EGLGRCSHALIRGVP	DDAH2	6	O95865
LCVLGAPRAGSGAHT	CRLF1	26	O75462
HSGVPAEVLCRGRDF	POLR3E	341	Q9NVU0
HPDSGEQTVRCRGRG	PDGFRB	426	P09619
GDCTILRGFGAHPAR	PARP10	766	Q53GL7
CFGRTRVVVPCGDGH	PARD3	6	Q8TEW0
AVRHVLALTGCGPGR	HGH1	41	Q9BTY7
DCGGGLRFIPRHTGL	EPHA6	381	Q9UF33
LRRHTLFHCVLGPGG	ITPRIPL2	446	Q3MIP1
CLPRDVRAGCRHSGG	MEGF6	1076	O75095
GGPVLSGVCRHLAAD	FAN1	936	Q9Y2M0
LRHGQLVVFGAPAGC	FREM3	476	P0C091
CKPRSVRRITGGGGH	SERGEF	46	Q9UGK8
PCGGAVHNATIGRVL	SEZ6L	451	Q9BYH1
CTFRPGGAVRGHLLG	PLEKHH3	341	Q7Z736
ARGHRPRLIGCGGIV	SLCO3A1	101	Q9UIG8
RPGDRVNLSCGGVSH	MPIG6B	26	O95866
GRQGLCVLRRLSGGH	PITRM1	6	Q5JRX3
QGRAFATVRLPFCGH	WIPI2	316	Q9Y4P8
TDLHCGFGGPLARVA	WDR18	176	Q9BV38
RLADGPHGCAGRLEV	SSC5D	21	A1L4H1
IHCVNIRPGDGLFRD	TEX45	271	Q8NA69
GEGCRTVPLAGHVGF	SEPTIN6	11	Q14141
RCSGEEFLGLGRVFH	PNMA6A	96	P0CW24
FHGEGVRQCGLGARP	CLRN1	66	P58418
LRQGTDRPLGGFHGC	SLIT3	1291	O75094
DRPLGGFHGCIHEVR	SLIT3	1296	O75094
HRIPSTICFGQGAAR	ZNF511	226	Q8NB15
GVGSSCLVLGARPHL	ZSWIM5	46	Q9P217
KHRRSPGERFLCGGI	PLAT	331	P00750
LLTHGGGQGRRPFKC	ZXDC	196	Q2QGD7
VPLSENGHDFRGRCL	TMEM179	26	Q6ZVK1
LGHPLGASGCRILVT	ACAT2	351	Q9BWD1
ESKRHGLPGVGLRTC	RYR3	1646	Q15413
QGRLCHVPRGVGLHG	UFSP1	31	Q6NVU6
GVLRHSVDLIGRPFG	TRMT61A	41	Q96FX7
PRGLREGLHYTEVCG	TPP2	601	P29144
GHFAAERRRLGPHVC	VWCE	31	Q96DN2
ERRRLGPHVCLSGFG	VWCE	36	Q96DN2
ALGFRHTCGGSVLAP	TMPRSS5	236	Q9H3S3
EARLVGGEHPCAGRL	SCART1	231	Q4G0T1
PRHGGRICVGKSREE	SEMA5B	696	Q9P283
LRVPGGRVQNIGHCF	WDR6	241	Q9NNW5
GGCTRPHVILREGLH	WDR6	686	Q9NNW5
AGPIIVHCSAGIGRT	PTPN6	446	P29350
LHLEPGSVESGRGRC	SEMA3G	156	Q9NS98
SGEEGRRCYPLAGHL	WTIP	391	A6NIX2
PVTGRCVSALGRRFH	TGFB1I1	411	O43294
GPTRCGLQGHTGRLL	PIEZO1	46	Q92508
RCEEAGCGGLLRPHV	SIRT5	206	Q9NXA8
SDCLVNRGGPGRSHV	TNNI3K	746	Q59H18
PAHGRLVCGREDGSI	WDR7	416	Q9Y4E6
AREGGEFTCRVQHPL	SIGLEC14	311	Q08ET2
ERHAFTCRVAGGPGT	TMEM25	46	Q86YD3
VLCHGGIFVPFLRAG	TYSND1	46	Q2T9J0
LGLVRCLRLGHRFGG	TSR3	81	Q9UJK0
CLRLGHRFGGLVLSP	TSR3	86	Q9UJK0
TDVVLRAGGRDFPCH	KLHL35	41	Q6PF15
VGGCLHELGPNRRSS	KLHL42	396	Q9P2K6
LCVDIGETRGGGHRP	MUS81	271	Q96NY9