Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

5.78e-0651683GO:0030156
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

TBX15 ALX3 ZNF536 CUX2 ZNF672 HIVEP2 CIART CALCOCO1 GATA3 ZNF619 KDM6B BATF2 ZNF692 CREBBP TLX2 SP8 NFATC1 TET1 PITX3 MITF DMRTC2 SIX5 TBXT DLX2 ELK1 MESP2 ARID3C TET3 MNT

1.23e-05145916829GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

TBX15 ZNF536 CUX2 HIVEP2 CIART CALCOCO1 GATA3 KDM6B BATF2 ZNF692 TLX2 SP8 NFATC1 TET1 PITX3 MITF DMRTC2 SIX5 TBXT DLX2 ELK1 MESP2 ARID3C TET3 MNT

4.43e-05124416825GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

TBX15 ZNF536 CUX2 HIVEP2 CIART CALCOCO1 GATA3 KDM6B BATF2 ZNF692 TLX2 SP8 NFATC1 TET1 PITX3 MITF DMRTC2 SIX5 TBXT DLX2 ELK1 MESP2 ARID3C TET3 MNT

6.27e-05127116825GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

TBX15 ALX3 ZNF536 CUX2 ZNF672 HIVEP2 GATA3 ADNP2 ZNF619 BATF2 ZNF692 ETV3L TLX2 SP8 KMT2D NFATC1 PITX3 MITF DMRTC2 SIX5 TBXT DLX2 ELK1 MESP2 ARID3C MNT

1.30e-04141216826GO:0000981
GeneOntologyMolecularFunction5-methylcytosine dioxygenase activity

TET1 TET3

2.10e-0431682GO:0070579
GeneOntologyMolecularFunctiontranscription coactivator activity

CALCOCO1 DAXX KMT2E CREBBP ZXDA KMT2C KMT2D ELK1 RERE MRTFA

2.54e-0430316810GO:0003713
GeneOntologyBiologicalProcessneuron projection development

CACNA1F ISLR2 FAT4 CUX2 NYAP2 ILK PSD MAPT GATA3 TRIOBP LAMA5 CREBBP TLX2 TAOK2 PARP6 ARHGEF40 TET1 IGSF9 ACP4 LGR6 RERE STRC PALLD MYO16 INPP5J MAPK8IP2 MRTFA STRCP1

1.52e-06128516728GO:0031175
GeneOntologyBiologicalProcessneuron development

CACNA1F ISLR2 FAT4 CUX2 NYAP2 ILK PSD MAPT GATA3 TRIOBP LAMA5 CREBBP TLX2 TAOK2 PARP6 ARHGEF40 RP1L1 TET1 PITX3 IGSF9 ACP4 LGR6 RERE STRC PALLD MYO16 INPP5J MAPK8IP2 MRTFA STRCP1

2.11e-06146316730GO:0048666
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

CACNA1F ISLR2 CUX2 ILK MAPT GATA3 TRIOBP LAMA5 TLX2 TAOK2 PARP6 ARHGEF40 TET1 IGSF9 LGR6 RERE STRC PALLD MAPK8IP2 STRCP1

2.87e-0674816720GO:0048667
GeneOntologyBiologicalProcessneuron projection morphogenesis

CACNA1F ISLR2 CUX2 NYAP2 ILK MAPT GATA3 LAMA5 TLX2 TAOK2 PARP6 ARHGEF40 TET1 IGSF9 LGR6 RERE PALLD MYO16 MAPK8IP2

2.81e-0580216719GO:0048812
GeneOntologyBiologicalProcessdendrite morphogenesis

CACNA1F CUX2 ILK TLX2 TAOK2 PARP6 TET1 RERE MAPK8IP2

3.50e-051981679GO:0048813
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

CACNA1F ISLR2 CUX2 NYAP2 ILK MAPT GATA3 LAMA5 TLX2 TAOK2 PARP6 ARHGEF40 TET1 IGSF9 LGR6 RERE PALLD MYO16 MAPK8IP2

3.74e-0581916719GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

CACNA1F ISLR2 CUX2 NYAP2 ILK MAPT GATA3 LAMA5 TLX2 TAOK2 PARP6 ARHGEF40 TET1 IGSF9 LGR6 RERE PALLD MYO16 MAPK8IP2

4.19e-0582616719GO:0048858
GeneOntologyBiologicalProcessdendrite development

CACNA1F CUX2 ILK CREBBP TLX2 TAOK2 PARP6 TET1 IGSF9 RERE MAPK8IP2

9.35e-0533516711GO:0016358
GeneOntologyBiologicalProcesscell morphogenesis

CACNA1F ISLR2 CUX2 NYAP2 ILK MAPT GATA3 TRIOBP LAMA5 TLX2 TAOK2 PARP6 ARHGEF40 TET1 FGD1 IGSF9 LGR6 RERE STRC PALLD MYO16 MAPK8IP2 STRCP1

9.79e-05119416723GO:0000902
GeneOntologyCellularComponentchromatin

TBX15 ALX3 CUX2 ICE2 CALCOCO1 GATA3 ADNP2 DAXX KMT2E BATF2 CREBBP WDR43 TLX2 SP8 PIAS3 NFATC1 TET1 PITX3 MITF DDX23 DMRTC2 SIX5 TBXT DLX2 ELK1 MESP2 MNT

4.61e-05148016727GO:0000785
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B DYNC1H1

6.93e-05281674GO:0002177
GeneOntologyCellularComponentMLL3/4 complex

KDM6B KMT2C KMT2D

1.04e-04121673GO:0044666
MousePhenoabnormal basement membrane morphology

FRAS1 ILK CRIM1 LAMA5 NID1

2.31e-05401215MP:0004272
MousePhenoabnormal neuropore morphology

LAMA5 CREBBP SP8 TET1 TBXT RERE

5.33e-05771216MP:0012542
MousePhenoabnormal head morphology

TBX15 ALX3 FRAS1 GATA3 LAMA5 BTAF1 FBXL19 LGR5 ITGB4 CREBBP SP8 KMT2D PRSS47P TET1 MITF OS9 TBXT DLX2 ACP4 LGR6 RERE WDFY3 MNT

7.97e-05112012123MP:0000432
MousePhenoabnormal facial morphology

TBX15 ALX3 FRAS1 GATA3 LAMA5 LGR5 ITGB4 CREBBP SP8 KMT2D PRSS47P TET1 MITF OS9 DLX2 ACP4 LGR6 RERE WDFY3 MNT

1.00e-0491012120MP:0003743
MousePhenoabnormal ureteric bud morphology

FAT4 FRAS1 ILK GATA3 LAMA5

1.31e-04571215MP:0006032
MousePhenobleb

FRAS1 CRIM1 TBXT

1.70e-04131213MP:0008854
MousePhenoabnormal viscerocranium morphology

TBX15 FRAS1 GATA3 LAMA5 CREBBP SP8 KMT2D PRSS47P TET1 MITF OS9 DLX2 ACP4 LGR6 MNT

1.83e-0459312115MP:0005274
MousePhenoabnormal jaw morphology

TBX15 FRAS1 GATA3 LAMA5 CREBBP SP8 KMT2D PRSS47P MITF OS9 DLX2 ACP4 LGR6 MNT

1.95e-0453012114MP:0000454
MousePhenoabnormal head development

ALX3 GATA3 BTAF1 FBXL19 SP8

1.95e-04621215MP:0012176
MousePhenoabnormal embryonic tissue morphology

TBX15 ALX3 FAT4 CUX2 ILK CRIM1 GATA3 LAMA5 FHOD3 DAXX FBXL19 CREBBP SNX13 TLX2 SP8 NFATC1 ADAMTS9 TET1 TBXT MESP2 RERE PALLD

2.10e-04111612122MP:0002085
MousePhenoabnormal mouth morphology

FRAS1 GATA3 LAMA5 LGR5 ITGB4 CREBBP SP8 PRSS47P MITF OS9 DLX2 ACP4 LGR6 RERE WDFY3 MNT

2.12e-0467012116MP:0000452
MousePhenodelayed head development

BTAF1 FBXL19

2.22e-0431212MP:0012177
MousePhenoabnormal craniofacial morphology

TBX15 ALX3 FRAS1 KIF6 CRIM1 GATA3 LAMA5 FBXL19 LGR5 ITGB4 CREBBP SP8 KMT2D PRSS47P TET1 MITF FGD1 OS9 TBXT DLX2 ACP4 LGR6 RERE WDFY3 MNT

2.49e-04137212125MP:0000428
MousePhenocraniofacial phenotype

TBX15 ALX3 FRAS1 KIF6 CRIM1 GATA3 LAMA5 FBXL19 LGR5 ITGB4 CREBBP SP8 KMT2D PRSS47P TET1 MITF FGD1 OS9 TBXT DLX2 ACP4 LGR6 RERE WDFY3 MNT

2.49e-04137212125MP:0005382
MousePhenoperinatal lethality

TBX15 ALX3 ISLR2 FAT4 ILK CRIM1 GATA3 KDM6B KMT2E LGR5 ITGB4 CREBBP PARP6 SP8 KMT2C TBXT DLX2 MESP2 RERE WDFY3 MNT DYNC1H1

2.51e-04113012122MP:0002081
DomainZnF_C2HC

FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

3.92e-07551587SM00343
DomainZnf_CCHC

FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

3.92e-07551587IPR001878
DomainZnf_FYVE_PHD

PHRF1 FBXL19 KMT2E ZFYVE28 KMT2C KMT2D FGD1 WDFY3

3.62e-051471588IPR011011
DomainSH3_9

RIMBP3 MAP3K9 RIMBP3C RIMBP3B MAP3K21 MAPK8IP2

5.18e-05781586PF14604
DomainGrowth_fac_rcpt_

FAT4 FRAS1 CRIM1 LAMA5 FBXL19 SVEP1 ELAPOR1 NID1

5.53e-051561588IPR009030
DomainTBD

TBKBP1 AZI2

2.12e-0431582PF12845
DomainTBD

TBKBP1 AZI2

2.12e-0431582IPR024581
DomainMLK1/MLK2/MLK4

MAP3K9 MAP3K21

4.22e-0441582IPR016231
DomainMAP3K10

MAP3K9 MAP3K21

4.22e-0441582IPR015785
DomainVWC_out

FRAS1 CRIM1 KCP

5.21e-04191583SM00215
DomainZnf_PHD-finger

PHRF1 FBXL19 KMT2E KMT2C KMT2D

5.54e-04791585IPR019787
DomainFYrich_C

KMT2C KMT2D

6.99e-0451582IPR003889
DomainFYrich_N

KMT2C KMT2D

6.99e-0451582IPR003888
DomainFYRC

KMT2C KMT2D

6.99e-0451582SM00542
DomainFYRN

KMT2C KMT2D

6.99e-0451582SM00541
DomainFYRN

KMT2C KMT2D

6.99e-0451582PF05964
DomainFYRC

KMT2C KMT2D

6.99e-0451582PF05965
DomainFYRC

KMT2C KMT2D

6.99e-0451582PS51543
DomainFYRN

KMT2C KMT2D

6.99e-0451582PS51542
DomainSH3_2

RUSC2 RIMBP3 MAP3K9 RIMBP3C RIMBP3B

8.16e-04861585PF07653
DomainSH3_2

RUSC2 RIMBP3 MAP3K9 RIMBP3C RIMBP3B

8.16e-04861585IPR011511
DomainPHD

PHRF1 FBXL19 KMT2E KMT2C KMT2D

9.53e-04891585SM00249
DomainGphrmn_rcpt_fam

LGR5 LGR6

1.04e-0361582IPR002131
Domainp53-like_TF_DNA-bd

TBX15 MYRFL NFATC1 TBXT

1.05e-03531584IPR008967
DomainZnf_PHD

PHRF1 FBXL19 KMT2E KMT2C KMT2D

1.05e-03911585IPR001965
Domain-

FAT4 LAMA5 SVEP1 LMAN1L WDFY3

1.28e-039515852.60.120.200
DomainZF_PHD_2

PHRF1 FBXL19 KMT2E KMT2C KMT2D

1.28e-03951585PS50016
DomainZF_PHD_1

PHRF1 FBXL19 KMT2E KMT2C KMT2D

1.34e-03961585PS01359
Pubmed

Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.

FAM90A14 FAM90A1 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

8.22e-22251741217684299
Pubmed

Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.

FAM90A14 FAM90A17 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10

8.18e-18231741018602769
Pubmed

Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.

FAM90A14 FAM90A1 FAM90A17 FAM90A19 MITF FAM90A22 FAM90A26 FAM90A23 FAM90A7 FAM90A9 FAM90A8 FAM90A10

4.54e-111641741222967998
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FAM193B FRAS1 HIVEP2 TBKBP1 ANKRD37 AKNA LAMA5 BTAF1 ATG2A FBXL19 KDM6B STK11IP ITGB4 BAHD1 TAOK2 PPP1R26 KMT2C ARHGEF40 KMT2D NFATC1 RIPOR1 DLX2 WDFY3 MAPKBP1 DYNC1H1

3.26e-1011051742535748872
Pubmed

A census of human transcription factors: function, expression and evolution.

TBX15 ALX3 CUX2 HIVEP2 GATA3 ADNP2 AKNA BATF2 TLX2 KMT2D NFATC1 PITX3 MITF DMRTC2 SIX5 TBXT DLX2 ELK1 MESP2 RERE MNT

6.54e-099081742119274049
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ISLR2 NYAP2 PHRF1 AKNA TRIOBP LAMA5 ATG2A KDM6B BAHD1 WDR43 TAOK2 ZFYVE28 KMT2C ST6GAL2 TET1 IGSF9

1.20e-085291741614621295
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

TBX15 ALX3 HIVEP2 CALCOCO1 GATA3 DAXX FBXL19 CREBBP TLX2 SP8 PIAS3 PITX3 MITF DMRTC2 DLX2 ELK1 RERE MRTFA

4.84e-078771741820211142
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

CREBBP KMT2C KMT2D

4.91e-074174328398509
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

4.91e-074174319091768
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FKBP15 ZNF536 FRAS1 SNX13 RUSC2 RIPOR1 RERE MAPKBP1 KIF17 TET3 DYNC1H1 PDZD2

1.12e-064071741212693553
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

1.22e-065174317855024
Pubmed

alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development.

LAMA5 ITGB4 NID1

2.43e-066174310934043
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM6B KMT2E KMT2C KMT2D

3.39e-0621174427626377
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

TBX15 ALX3 CUX2 GATA3 TLX2 SP8 NFATC1 PITX3 DMRTC2 TBXT DLX2 ELK1 MESP2

4.01e-065441741328473536
Pubmed

alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.

LAMA5 ITGB4 NID1

4.24e-06717439151677
Pubmed

Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.

FRAS1 LAMA5 NID1

6.77e-068174312766770
Pubmed

Dynamic expression of Runx1 in skin affects hair structure.

GATA3 ITGB4 MITF

6.77e-068174317011173
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

KMT2E KMT2C KMT2D

6.77e-068174323130995
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM6B KMT2E CREBBP KMT2C KMT2D

1.00e-0557174518022353
Pubmed

Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation.

LAMA5 NID1 TBXT

1.01e-059174315102706
Pubmed

Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response.

DAXX CREBBP ELK1

1.01e-059174323395904
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ISLR2 FRAS1 NYAP2 CALCOCO1 PHRF1 KMT2C

1.38e-05103174610819331
Pubmed

Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome.

FRAS1 LAMA5 NID1

1.44e-0510174315623520
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

FBXL19 TET1 TET3

1.44e-0510174329276034
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZNF536 KDM6B N4BP3 RUSC2 DYNC1H1 PDZD2

1.45e-0510417469205841
Pubmed

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.

GATA3 LAMA5 ITGB4 NID1

1.71e-0531174422274697
Pubmed

MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner.

KMT2C KMT2D TBXT

1.97e-0511174337012455
Pubmed

Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor.

PIAS3 NFATC1 MITF

1.97e-0511174317442941
Pubmed

Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer.

LGR5 LGR6

2.49e-052174222002312
Pubmed

Identification, expression analysis, genomic organization and cellular location of a novel protein with a RhoGEF domain.

MAPT ARHGEF40

2.49e-052174216143467
Pubmed

Tet3-Mediated DNA Demethylation Contributes to the Direct Conversion of Fibroblast to Functional Neuron.

MAPT TET3

2.49e-052174227880907
Pubmed

The junctional epithelium originates from the odontogenic epithelium of an erupted tooth.

LAMA5 ITGB4

2.49e-052174224785116
Pubmed

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

KMT2C KMT2D

2.49e-052174231924266
Pubmed

TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment.

KDM6B TET3

2.49e-052174232405722
Pubmed

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability.

KMT2C KMT2D

2.49e-052174228967912
Pubmed

CBP/p300 as a co-factor for the Microphthalmia transcription factor.

CREBBP MITF

2.49e-05217429223672
Pubmed

Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.

STRC STRCP1

2.49e-052174234910522
Pubmed

SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx.

DAXX CREBBP

2.49e-052174216287980
Pubmed

Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation.

TET1 TET3

2.49e-052174226711116
Pubmed

Role played by microphthalmia transcription factor phosphorylation and its Zip domain in its transcriptional inhibition by PIAS3.

PIAS3 MITF

2.49e-052174214645519
Pubmed

The utility of synovial fluid levels of ADAMTS9 and ADAMTS4 in predicting treatment responses to intraarticular steroid injections in patients with knee osteoarthritis.

ADAMTS4 ADAMTS9

2.49e-052174232490633
Pubmed

A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.

CREBBP KMT2D

2.49e-052174227999180
Pubmed

Association of KMT2C/D loss-of-function variants with response to immune checkpoint blockades in colorectal cancer.

KMT2C KMT2D

2.49e-052174236601880
Pubmed

JMJD3 is Involved in Intracranial Aneurysm Development by Regulating DLX2 Expression through H3K27me3 Modification.

KDM6B DLX2

2.49e-052174237286519
Pubmed

Epigenetic regulation of intestinal stem cells by Tet1-mediated DNA hydroxymethylation.

LGR5 TET1

2.49e-052174227856615
Pubmed

Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation.

KMT2C KMT2D

2.49e-052174228483418
Pubmed

Cten signals through integrin-linked kinase (ILK) and may promote metastasis in colorectal cancer.

ILK TNS4

2.49e-052174221339732
Pubmed

[Expression and Significance of Leucine-rich Repeat-containing G-protein Coupled Receptor 5/6 in Wnt Pathway in Children with Acute Lymphoblastic Leukemia].

LGR5 LGR6

2.49e-052174234494532
Pubmed

The MLL3/4 H3K4 methyltransferase complex in establishing an active enhancer landscape.

KMT2C KMT2D

2.49e-052174234156443
Pubmed

Epigenetic regulation of osteoclast differentiation: possible involvement of Jmjd3 in the histone demethylation of Nfatc1.

KDM6B NFATC1

2.49e-052174221735477
Pubmed

Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.

STRC STRCP1

2.49e-052174211687802
Pubmed

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes.

TET1 TET3

2.49e-052174226703470
Pubmed

Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.

TET1 TET3

2.49e-052174226294212
Pubmed

Redox-Sensitive Regulation of Myocardin-Related Transcription Factor (MRTF-A) Phosphorylation via Palladin in Vascular Smooth Muscle Cell Differentiation Marker Gene Expression.

PALLD MRTFA

2.49e-052174227088725
Pubmed

A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor.

PIAS3 MITF

2.49e-052174211709556
Pubmed

Reduced Expression of Histone Methyltransferases KMT2C and KMT2D Correlates with Improved Outcome in Pancreatic Ductal Adenocarcinoma.

KMT2C KMT2D

2.49e-052174227280393
Pubmed

Intrinsic Tau Acetylation Is Coupled to Auto-Proteolytic Tau Fragmentation.

MAPT CREBBP

2.49e-052174227383765
Pubmed

Loss of MLL3/4 decouples enhancer H3K4 monomethylation, H3K27 acetylation, and gene activation during embryonic stem cell differentiation.

KMT2C KMT2D

2.49e-052174236869380
Pubmed

KDM6B cooperates with Tau and regulates synaptic plasticity and cognition via inducing VGLUT1/2.

MAPT KDM6B

2.49e-052174236028572
Pubmed

Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice.

KMT2C KMT2D

2.49e-052174225346535
Pubmed

Altered expression of MLL methyltransferase family genes in breast cancer.

KMT2E KMT2D

2.49e-052174223754336
Pubmed

Long-term expansion and differentiation of adult murine epidermal stem cells in 3D organoid cultures.

LGR5 LGR6

2.49e-052174231253707
Pubmed

Restraint of IFN-γ expression through a distal silencer CNS-28 for tissue homeostasis.

GATA3 KMT2D

2.49e-052174237040761
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

4.30e-0514174317662146
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

CREBBP KMT2C KMT2D

4.30e-0514174312482968
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

THSD7A BAHD1 TAOK2 PPP1R26 MYO16 PDZD2

5.14e-05130174612421765
Pubmed

Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling.

TET1 TBXT TET3

5.36e-0515174327930333
Pubmed

DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation.

GATA3 TET1 TET3

5.36e-0515174336630508
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

TBX15 ZNF536 CUX2 HIVEP2 GATA3 ZNF692 CREBBP KMT2C ST6GAL2 PIAS3 SIX5 TBXT MNT

6.37e-057091741322988430
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

ADAMTS4 LAMA5 ADAMTS9

6.57e-0516174330579834
Pubmed

Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.

TET1 TET3

7.44e-053174224194590
Pubmed

TET proteins in malignant hematopoiesis.

TET1 TET3

7.44e-053174219923888
Pubmed

Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation.

CREBBP KMT2D

7.44e-053174234463256
Pubmed

Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.

STRC STRCP1

7.44e-053174230801007
Pubmed

ADAMTS9 activation by interleukin 1 beta via NFATc1 in OUMS-27 chondrosarcoma cells and in human chondrocytes.

NFATC1 ADAMTS9

7.44e-053174219052845
Pubmed

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.

TET1 TET3

7.44e-053174221778364
Pubmed

Tet family proteins and 5-hydroxymethylcytosine in development and disease.

TET1 TET3

7.44e-053174222569552
Pubmed

TAO (thousand-and-one amino acid) protein kinases mediate signaling from carbachol to p38 mitogen-activated protein kinase and ternary complex factors.

TAOK2 ELK1

7.44e-053174212665513
Pubmed

The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells.

DAXX CREBBP

7.44e-053174211799127
Pubmed

Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.

KMT2C KMT2D

7.44e-053174223932714
Pubmed

Tacrolimus and cyclosporine A inhibit human osteoclast formation via targeting the calcineurin-dependent NFAT pathway and an activation pathway for c-Jun or MITF in rheumatoid arthritis.

NFATC1 MITF

7.44e-053174216586042
Pubmed

The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7.

LGR5 LGR6

7.44e-053174210935549
Pubmed

Inactivation of integrin-linked kinase induces aberrant tau phosphorylation via sustained activation of glycogen synthase kinase 3beta in N1E-115 neuroblastoma cells.

ILK MAPT

7.44e-053174212714590
Pubmed

Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.

TET1 TET3

7.44e-053174223548903
Pubmed

5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.

TET1 TET3

7.44e-053174234919053
Pubmed

Lgr6 marks nail stem cells and is required for digit tip regeneration.

LGR5 LGR6

7.44e-053174226460010
Pubmed

Reduced Expression of TET1, TET2, TET3 and TDG mRNAs Are Associated with Poor Prognosis of Patients with Early Breast Cancer.

TET1 TET3

7.44e-053174226207381
Pubmed

Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma.

KMT2C KMT2D

7.44e-053174222183980
Pubmed

Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.

TET1 TET3

7.44e-053174222445327
Pubmed

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.

TET1 TET3

7.44e-053174224735881
Pubmed

Inhibition of NF-kappaB acetylation and its transcriptional activity by Daxx.

DAXX CREBBP

7.44e-053174217362989
Pubmed

Runx3 is involved in hair shape determination.

ITGB4 MITF

7.44e-053174215937937
Pubmed

Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing.

LGR5 LGR6

7.44e-053174230332640
Pubmed

Integrin-linked kinase regulates the niche of quiescent epidermal stem cells.

ILK LGR5

7.44e-053174226349061
Pubmed

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.

TET1 TET3

7.44e-053174220639862
Pubmed

Ten-Eleven Translocation Genes are Downregulated in Endometriosis.

TET1 TET3

7.44e-053174226917261
Pubmed

HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

KMT2C KMT2D

7.44e-053174221683083
Pubmed

Alternation of ten-eleven translocation 1, 2, and 3 expression in eutopic endometrium of women with endometriosis-associated infertility.

TET1 TET3

7.44e-053174230130982
Pubmed

Regulation of DNA methylation signatures on NF-κB and STAT3 pathway genes and TET activity in cigarette smoke extract-challenged cells/COPD exacerbation model in vitro.

TET1 TET3

7.44e-053174232342329
Pubmed

PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit.

CREBBP PIAS3

7.44e-053174215140884
InteractionEGR2 interactions

ZNF536 HIVEP2 CREBBP KMT2C KMT2D NFATC1 TET1 MITF RERE

6.82e-061711549int:EGR2
Cytoband8p23.1

FAM90A14 FAM90A17 RP1L1 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

8.99e-13154174128p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

FAM90A14 FAM90A17 RP1L1 FAM90A19 FAM90A22 FAM90A23 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

1.22e-1023417412chr8p23
CytobandEnsembl 112 genes in cytogenetic band chr15q15

ANKRD63 BAHD1 STRC MAPKBP1 STRCP1

2.55e-041471745chr15q15
Cytoband9q32

FKBP15 AKNA SVEP1

7.68e-044717439q32
Cytoband15q15.1

ANKRD63 BAHD1 MAPKBP1

7.68e-0447174315q15.1
Cytoband16p11.2

TMEM219 FBXL19 ITGAM PRSS36 TAOK2

8.41e-04191174516p11.2
GeneFamilyZinc fingers CXXC-type

FBXL19 TET1 TET3

4.15e-05121063136
GeneFamilyPHD finger proteins

PHRF1 FBXL19 KMT2E KMT2C KMT2D

1.86e-0490106588
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

TAOK2 MAP3K9 MAP3K21

3.62e-04241063654
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PLEKHG2 ARHGEF40 ARHGEF33 FGD1

6.08e-04661064722
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

FKBP15 MAPT PHRF1 WDR81 PPP1R26 MYO16

6.91e-041811066694
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

ZFYVE28 FGD1 WDFY3

7.81e-0431106381
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2E KMT2C KMT2D

1.03e-03341063487
GeneFamilyWD repeat domain containing|BEACH domain containing

WDR81 WDFY3

1.19e-03910621230
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATA3 RERE

3.40e-0315106282
GeneFamilyT-boxes

TBX15 TBXT

4.90e-03181062766
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS4 ADAMTS9

5.46e-0319106250
GeneFamilyProteases, serine

PRSS36 PRSS47P TPSG1

6.03e-03631063738
CoexpressionGSE22886_IL2_VS_IL15_STIM_NKCELL_UP

ALX3 ZNF536 FRAS1 LAMA5 B3GNT3 ITGB4 TAOK2 MAP3K9 OS9

4.24e-061961649M4514
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

FAT4 FRAS1 CRIM1 GATA3 ADNP2 TRIOBP KDM6B CREBBP KMT2C CCNI PALLD MNT PDZD2

8.25e-0646716413M1347
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN

FAT4 FRAS1 CRIM1 GATA3 ADNP2 TRIOBP KDM6B CREBBP KMT2C CCNI PALLD MNT PDZD2

1.21e-0548416413MM999
CoexpressionSMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN

MAPT GATA3 ELAPOR1 GREB1 MAPKBP1 INPP5J

1.29e-05821646M244
CoexpressionBENPORATH_PRC2_TARGETS

ALX3 MAPT OTOP2 GATA3 LGR5 TLX2 RIMBP3 ZFYVE28 PITX3 ELAPOR1 DGKI RIMBP3C DLX2 RIMBP3B PDZD2

1.54e-0565016415M8448
CoexpressionGSE37532_WT_VS_PPARG_KO_LN_TREG_UP

FKBP15 CALCOCO1 TOM1 GATA3 KDM6B ST6GAL2 PIAS3 TET1

1.58e-051761648M8952
CoexpressionGSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_UP

CRIM1 AKNA DAXX PLEKHG2 KMT2E CREBBP FAM117A OS9

3.95e-052001648M7430
CoexpressionAtlasEctoderm Differentiated Cells_vs_Endoderm Differentiated Cells-Confounder_removed-fold2.0_adjp0.05

FAM193B PRR36 CIART CALCOCO1 LAMA5 LMNTD2 FHOD3 BTAF1 ADAM11 KDM6B SEC31B ZNF692 RUSC2 SP8 FAM117A ADAMTS9 NID1 IGSF9 RIPOR1 GREB1 PALLD MRTFA

1.30e-05107515622PCBC_ratio_ECTO_vs_DE_cfr-2X-p05
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_500_k-means-cluster#3

ZNF536 THSD7A FHOD3 ZFYVE28 KIAA1549L TET1 SLAIN1

2.69e-051181567Facebase_RNAseq_e8.5_Floor Plate_500_K3
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ISLR2 CUX2 NYAP2 MAPT GATA3 TLX2 DGKI MAPK8IP2

4.26e-071841648571136c832cb8c08457744152231537aa8e8abd7
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CUX2 NYAP2 MAPT GATA3 TLX2 DGKI DLX2 MAPK8IP2

4.62e-0718616482fdd0a80ad31cf017aafcf5dcf760ebd786b98c1
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ISLR2 CUX2 NYAP2 MAPT GATA3 TLX2 DLX2 MAPK8IP2

5.65e-0719116483a5081dc542ac6262acfe5f8084a86616fee8082
ToppCell11.5-Airway-Epithelial-Epithelial|Airway / Age, Tissue, Lineage and Cell class

CUX2 NYAP2 MAPT GATA3 FHOD3 TLX2 DLX2 MAPK8IP2

5.88e-071921648a77d3692ff02ef7e066a9bd9e22725055a25c4d4
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT4 ZNF536 KIF6 HTR4 SP8 DLX2 TPSG1

1.78e-0615516473b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell10x5'-blood-Lymphocytic_T_CD4-Trm_Th1/Th17|blood / Manually curated celltypes from each tissue

TBKBP1 CRIM1 ZNF619 SLAIN1 ELK1 TNS4 SAMD4A

1.94e-061571647c99cb26d831c25038f2aa1b1c0f7ba52facb2e7a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 NYAP2 THSD7A PTPN21 ST6GAL2 MYO16 PDZD2

4.61e-0617916474f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 LAMA5 KDM6B ITGB4 ADAMTS9 GREB1 PALLD

4.78e-061801647af2bafcd1b2082629de3ea336711add01565c4c4
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 HIVEP2 ADAMTS4 KDM6B SVEP1 ADAMTS9 GREB1

4.78e-06180164712537d8a569faa69f474284d2c201475722b8ca1
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 LAMA5 KDM6B ITGB4 ADAMTS9 GREB1 PALLD

4.78e-061801647f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NYAP2 HTR4 ANKRD63 ZFYVE28 KIAA1549L KIF17

5.15e-061821647d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR2 CUX2 PRR36 FHOD3 GRIK5 TLX2 MAPK8IP2

5.15e-061821647be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 NYAP2 HTR4 ANKRD63 ZFYVE28 KIAA1549L KIF17

5.15e-0618216476cde859edfe7607bd7ada89d20258413d06f4207
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

FRAS1 CUX2 FHOD3 ITGB4 ST6GAL2 ELAPOR1 TNS4

5.33e-06183164700a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 AKNA MYRFL ADAMTS9 MITF GREB1 INPP5J

5.33e-0618316475a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 HTR4 MYRFL MITF GREB1 MYO16 INPP5J

5.53e-0618416472ba98708dfd7f1b2a661578a334684094ff453ad
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR2 CUX2 MAPT FHOD3 TLX2 DGKI MAPK8IP2

5.53e-061841647abb61e744a9031e0c91eb560a8f486a0ca5a01cc
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

NYAP2 THSD7A LAMA5 PTPN21 MYO16 SAMD4A PDZD2

5.53e-061841647561592edc3083fad41b91811151b442207c65dd9
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FRAS1 FBXL19 LGR5 ZXDA KMT2D GREB1 MAP3K21

5.73e-061851647636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

NYAP2 THSD7A LAMA5 PTPN21 MYO16 SAMD4A PDZD2

6.15e-06187164777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 AKNA MYRFL MITF GREB1 MYO16 INPP5J

6.59e-06189164778cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 AKNA MYRFL ADAMTS9 MITF GREB1 INPP5J

6.82e-06190164726843ec1d19ac85a50990705353b802745d33e4d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 HTR4 MYRFL MITF GREB1 MYO16 INPP5J

6.82e-0619016473f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 HTR4 MYRFL MITF GREB1 MYO16 INPP5J

6.82e-06190164739ab890104b4264c68a968f920f4ccd84f0bc681
ToppCelldistal-1-Hematologic-CD4+_Memory/Effector_T|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ATG9B GATA3 FAM117A CD6 PIAS3 RUSC1-AS1 TRAF3IP3

7.30e-061921647e2611de161d629d901765ca0e4db75bb65096a25
ToppCellwk_08-11-Epithelial-PNS-KCNIP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CUX2 MAPT GATA3 TLX2 ST6GAL2 DGKI DLX2

7.30e-06192164753642c88891f4e4e14b1740c5ced759b7d8b3572
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FHOD3 LGR5 AOC3 GREB1 LGR6 PALLD SAMD4A

7.30e-0619216472cc712186e37fb21a964c032765c36a8b4a852cf
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

THSD7A CRIM1 ADAMTS4 B3GNT3 ITGB4 ADAMTS9 KIF17

7.81e-0619416472e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

THSD7A CRIM1 ADAMTS4 B3GNT3 ITGB4 ADAMTS9 KIF17

7.81e-061941647b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCellBronchus_Control_(B.)-Epithelial-TX-AT2-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FRAS1 ATG2A N4BP3 ZXDA DLX2 TNS4 PDZD2

7.81e-0619416475bfc26668fa8f109f2ebc0d5fd98ab5bd219e62c
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 CUX2 FHOD3 ITGB4 ST6GAL2 ELAPOR1 TNS4

8.08e-0619516476c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCellfacs-Skin-nan-18m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 LGR5 SVEP1 ARHGEF40 NFATC1 MITF PALLD

8.08e-061951647ba7cb80deb872c9184769f0dd57855c3c6a432bf
ToppCellwk_08-11-Epithelial-PNS-TM4SF4+_PENK+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ISLR2 NYAP2 MAPT GATA3 TLX2 DLX2 MAPK8IP2

8.35e-061961647afa3a2f5f3a51d1830c6f95f97a4b3e13ed42512
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CRIM1 ADAMTS4 LAMA5 MYRFL ADAMTS9 AOC3 LGR6

8.35e-0619616471d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell5'-Adult-Appendix|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 KDM6B SVEP1 WDR43 NFATC1 ADAMTS9 NID1

8.35e-061961647a579211ef14f348d0c5a290553150222dfbf1515
ToppCell367C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CRIM1 ADAMTS4 LAMA5 MYRFL ADAMTS9 AOC3 LGR6

8.35e-061961647aacec48285bcb7ccf1b538187071885e3602cc49
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR2 THSD7A MAPT FHOD3 TLX2 DLX2 MAPK8IP2

8.63e-061971647fd43fc1cbf0c17b370397d73dddc572565a759c7
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_3|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

ZNF536 MAPT SP8 SLAIN1 DLX2 RERE CCNI

8.63e-061971647d77bc37a77546a1f0a508486a38a45e571e4645b
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF536 ILK FHOD3 GREB1 LGR6 PALLD SAMD4A

8.92e-06198164763f7d25201613bd3404c28fb936954190bca91d3
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF536 ILK FHOD3 GREB1 LGR6 PALLD SAMD4A

8.92e-061981647a73534b6ca202c277a70a52281d5b97a3e6cb8ef
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 LAMA5 FHOD3 ITGB4 ST6GAL2 TNS4 LGR6

9.22e-06199164794a7867e800df352731796de8c24cba133c29622
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FKBP15 MAPT PLEKHG2 BATF2 PRSS36 SIX5

1.09e-0513516467e3c840b40c41715ff7120a88b8b3f223df4f25a
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-Smooth_Muscle-like_MyoFibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

PSD FHOD3 ST6GAL2 LGR6 TPSG1 SAMD4A

1.34e-0514016465623a0a68403fc00166b7d13d13e184a718d9bdd
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NYAP2 STK11IP ITGB4 KRBA1 TNS4 TPSG1

2.22e-05153164692a5307b8e4dcf9ee42134b4c0645f9d488df61a
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 LAMA5 FHOD3 ITGB4 ELAPOR1 TNS4

2.57e-0515716466ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 LAMA5 FHOD3 ITGB4 ELAPOR1 TNS4

2.66e-051581646d78e7e52657dc094430291fec07e9c298be9e584
ToppCellBasal_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 NYAP2 TBKBP1 ST6GAL2 FGD1 NID1

2.66e-051581646dd069a822e9698e6dddc155d9a5b52383f7879d5
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KIF6 CRIM1 MAPT ITGB4 AOC3 IBA57-DT

2.85e-0516016460293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

KIF6 CRIM1 MAPT ITGB4 AOC3 IBA57-DT

2.85e-0516016463eaae86fa08f7651021316f8e5811bf48055591e
ToppCelldroplet-Liver-Hepatocytes-21m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 LMNTD2 CD6 SLAIN1 TRAF3IP3 MUTYH

3.06e-051621646eb2900a250fb3e08e479c727c7d3200cbcf37fbc
ToppCelldroplet-Liver-Hepatocytes-21m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GATA3 LMNTD2 CD6 SLAIN1 TRAF3IP3 MUTYH

3.06e-0516216461ef3084b5766641ec07c6f488c1756239cf3fd61
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 ST6GAL2 AOC3 NID1 LGR6 STRC

3.17e-05163164651dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCelldroplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBX15 ALX3 FAT4 SVEP1 ARHGEF40 KIF17

4.01e-05170164610e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Chat_Htr1f|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT4 ZNF536 HTR4 LAMA5 SP8 DLX2

4.14e-051711646f9ae7964a3740f559431125c17c660549798cccc
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF536 GATA3 SP8 CD6 SLAIN1 MAPK8IP2

4.28e-051721646f45489e80c59b824846ffda675de0d118a8b850c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATG9B ZNF672 ADAMTS4 ZXDA PPP1R26 MAP3K21

4.42e-05173164623e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCellmetastatic_Brain-Endothelial_cells-Stalk-like_ECs|Endothelial_cells / Location, Cell class and cell subclass

KIF6 LMNTD2 PPP1R26 KRBA1 MAP3K9 PALLD

4.71e-051751646f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 MYRFL MITF DLX2 MYO16 INPP5J

4.86e-051761646682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PHRF1 KCP PLEKHG2 RUSC2 KMT2C PIAS3

5.02e-051771646eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRAS1 LAMA5 FHOD3 ITGB4 ELAPOR1 TNS4

5.18e-051781646fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 MYRFL MITF GREB1 MYO16 INPP5J

5.34e-051791646d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 SVEP1 LMAN1L SP8 NID1 MYO16

5.34e-0517916460b6731d9554f8bed1899c165a50e6b329ea19a6d
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

FRAS1 LAMA5 FHOD3 ITGB4 ELAPOR1 TNS4

5.34e-051791646d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 FRAS1 KIF6 MAPT DLX2 KIF17

5.68e-0518116463aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 FRAS1 KIF6 MAPT DLX2 KIF17

5.68e-051811646997ba1be2824b00d684f2163d0114656ed11fa53
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 FRAS1 SVEP1 SP8 DLX2 CCNI

5.68e-0518116466c55985e464cb0f5fb3362e9fd90351b671950f7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 THSD7A GATA3 FHOD3 MAP3K21 INPP5J

5.68e-051811646aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF536 FRAS1 KIF6 MAPT DLX2 KIF17

5.68e-051811646e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCell10x5'v1-week_17-19-Lymphocytic_T-T_NK-CD8_T_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FRAS1 HIVEP2 SEC31B ZFYVE28 CD6 TRAF3IP3

5.86e-05182164698c26ad34e01c4b8997d26d5d28a9935491295fa
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZNF536 CUX2 NYAP2 TLX2 DLX2 MAPK8IP2

6.04e-0518316469dfb398b9995d562864fe688861a831ada0814cd
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRIM1 ADAMTS4 MAPT KCP NID1 PDZD2

6.22e-051841646327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

NYAP2 LAMA5 PTPN21 MYO16 SAMD4A PDZD2

6.41e-0518516461c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 ZNF536 THSD7A SVEP1 SP8 DLX2

6.41e-051851646cefd81adb480c027545a5c78dcd05669783717f4
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZNF536 CUX2 NYAP2 TLX2 DLX2 MAPK8IP2

6.41e-051851646512f489daeb3b72d4578dc6f4d0ebb5f38d5bbab
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 CUX2 HTR4 AKNA MITF MYO16

6.41e-051851646e87e6e097dc29ece8aea671935bde281b99b93ea
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 MYRFL MITF GREB1 MYO16 INPP5J

6.61e-051861646948815663c212c4311329d503b5991cbbbff9808
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR2 MAPT FHOD3 TLX2 DLX2 MAPK8IP2

6.80e-051871646a748b3a59e398e0da019db3f16d38adb1960c29f
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 MAPT KCP AOC3 DGKI NID1

6.80e-051871646fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 SVEP1 SP8 NID1 PALLD MYO16

6.80e-051871646d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Reln_(Cajal-Retzius)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CACNA1F IGSF9 MESP2 GREB1 STRC

7.01e-0511616451bfd3b0ec4cb5a04c6dfe7861a544eb277e473a3
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Reln_(Cajal-Retzius)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CACNA1F IGSF9 MESP2 GREB1 STRC

7.01e-051161645a3dcd18807d14e207438f321be62797384fd3907
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CACNA1F IGSF9 MESP2 GREB1 STRC

7.01e-051161645685484ea4cbefb5aff5f0cd999fdfadc5a5676e1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 ZNF536 THSD7A SVEP1 SP8 DLX2

7.01e-0518816466ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 HTR4 FHOD3 NID1 LGR6 PALLD

7.01e-0518816463177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 ZNF536 THSD7A SVEP1 SP8 DLX2

7.01e-051881646c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 MAPT KCP AOC3 NID1 PDZD2

7.01e-051881646ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NYAP2 B3GNT3 NFATC1 MITF DGKI PALLD

7.01e-051881646762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 MYRFL MITF GREB1 MYO16 INPP5J

7.01e-0518816468de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Ung))|Striatum / BrainAtlas - Mouse McCarroll V32

LMNTD2 ACP4 GREB1 ARID3C

7.08e-05601644eb1095bce18184254db2691f31e5d3f40da279a1
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

THSD7A CRIM1 ITGB4 KIAA1549L ADAMTS9 DGKI

7.22e-0518916467346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CUX2 NYAP2 GATA3 TLX2 DGKI DLX2

7.22e-051891646de06ef69f3f97b3f21dc269eb6965da9b2f6e3f8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF536 HTR4 CRIM1 NID1 LGR6 PALLD

7.22e-0518916467ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ISLR2 CUX2 MAPT FHOD3 TLX2 MAPK8IP2

7.22e-051891646cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

THSD7A LAMA5 PTPN21 PALLD SAMD4A PDZD2

7.22e-0518916465a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA5 PTPN21 PALLD MYO16 SAMD4A PDZD2

7.43e-05190164630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellhuman_hepatoblastoma-Endothelial_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

THSD7A N4BP3 NFATC1 ADAMTS9 DGKI PDZD2

7.43e-0519016468d6ef93d69e96cd6921816d152bea3b0710cf147
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRIM1 MAPT PLEKHG2 AOC3 NID1 PDZD2

7.43e-051901646951e067d14412db67dc3babcdf61e41717d7b429
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF536 HTR4 MYRFL MITF MYO16 INPP5J

7.43e-0519016460acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT4 ZNF536 THSD7A SVEP1 SP8 DLX2

7.65e-051911646764c3a8829ae1253a0790744138266e81fc075ec
ToppCellwk_08-11-Epithelial-PNS-SST+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ISLR2 NYAP2 MAPT GATA3 TLX2 MAPK8IP2

7.65e-051911646df2bef74a54f4c23c99bd3b93225fd36bcd90723
ComputationalNeighborhood of FDXR

FKBP15 HTR4 CALCOCO1 GRIK5 BAHD1 CD6 ELK1 RERE MUTYH

8.46e-05226879MORF_FDXR
Diseasecup-to-disc ratio measurement

FAT4 FRAS1 KIF6 TRIOBP FHOD3 KIAA1549L CROCC2 TET1 RERE MYO16 PDZD2

1.11e-0543014711EFO_0006939
Diseasecortical thickness

ZNF536 KIF6 NYAP2 CRIM1 MAPT SEM1 TRIOBP ETV3L LMAN1L SP8 ARHGEF40 ADAMTS9 MITF DGKI IGSF9 RERE MYO16 PDZD2

1.15e-05111314718EFO_0004840
DiseaseKleefstra syndrome 2 (implicated_via_orthology)

KMT2C KMT2D

2.47e-0521472DOID:0080598 (implicated_via_orthology)
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

2.47e-0521472DOID:0110471 (implicated_via_orthology)
Diseaseoral microbiome measurement

FRAS1 GRIK5 KMT2C PDZD2

5.71e-05421474EFO_0801229
Diseaseprostate cancer (is_marker_for)

ILK DAXX KMT2E KMT2C KMT2D FGD1

1.36e-041561476DOID:10283 (is_marker_for)
DiseaseSezary Syndrome

CREBBP KMT2C KMT2D

3.25e-04271473C0036920
Diseasecortical surface area measurement

ALX3 ZNF536 KIF6 NYAP2 MAPT SEM1 TRIOBP SVEP1 SNX13 SP8 ADAMTS9 RP1L1 DGKI IGSF9 RERE MYO16 PDZD2

3.99e-04134514717EFO_0010736
Diseaseage at diagnosis, osteoarthritis

MAPT RP1L1

5.09e-0471472EFO_0004918, MONDO_0005178
DiseaseNephronophthisis, familial juvenile

ADAMTS9 MAPKBP1

5.09e-0471472C1855681
Diseaseblood pressure, chronic obstructive pulmonary disease

TMEM219 HTR4 RERE

5.40e-04321473EFO_0000341, EFO_0004325
Diseaselobe attachment

TBX15 FAT4 KIF6 HIVEP2 SEM1 TOM1

6.17e-042071476EFO_0007667
Diseasetestosterone measurement

ZNF536 CUX2 NYAP2 MAPT ICE2 WDR81 AKNA PTPN21 KDM6B ARHGEF40 NFATC1 FGD1 DGKI GREB1 ARID3C MYO16

6.43e-04127514716EFO_0004908
Diseasebipolar disorder

HIVEP2 THSD7A TMEM219 GRIK5 PRSS36 SVEP1 TAOK2 SP8 KMT2D SERGEF

6.57e-0457714710MONDO_0004985
DiseaseAutistic behavior

CUX2 TET3

6.77e-0481472C0856975
DiseaseQRS duration

FAT4 NYAP2 CRIM1 FHOD3 SP8 MITF PALLD

7.63e-042981477EFO_0005055
Diseaseinterventricular septum thickness

MAPT MITF

1.08e-03101472EFO_0009287
DiseaseCongenital small ears

FRAS1 KMT2D SIX5

1.12e-03411473C0152423
Diseasehypertrophic cardiomyopathy

KCP FHOD3 KMT2C MITF

1.18e-03921474EFO_0000538
DiseaseMicrophthalmos

KMT2D PITX3

1.32e-03111472C0026010
DiseaseSquamous cell carcinoma of esophagus

FAT4 CREBBP KMT2C KMT2D

1.32e-03951474C0279626
Diseasevital capacity

TBX15 NYAP2 HIVEP2 HTR4 CRIM1 MAPT KMT2E SVEP1 SNX13 CROCC2 RIPOR1 MAPKBP1 MYO16 SAMD4A PDZD2

1.33e-03123614715EFO_0004312
Diseaseneutrophil count

TBX15 CUX2 HIVEP2 HTR4 MAPT PLEKHG2 KDM6B KMT2E CREBBP SNX13 RP1L1 SERGEF MITF ELAPOR1 TRAF3IP3 RERE

1.49e-03138214716EFO_0004833
DiseaseAdenoid Cystic Carcinoma

KDM6B ITGB4 CREBBP KMT2C

1.60e-031001474C0010606
Diseaseblood phosphate measurement

CUX2 TBKBP1 GATA3 OS9 KIF17

1.83e-031741475EFO_0010972
Diseasehematologic cancer (implicated_via_orthology)

CUX2 PIAS3

1.85e-03131472DOID:2531 (implicated_via_orthology)
DiseaseQRS amplitude, QRS complex

CRIM1 MAPT MITF

2.00e-03501473EFO_0005054, EFO_0007742
Diseaseinflammatory biomarker measurement, YKL40 measurement

ZFYVE28 ST6GAL2 MYO16

2.12e-03511473EFO_0004869, EFO_0004872
Diseasefacial morphology measurement

TBX15 FAT4 KIF6 SEM1 NID1 PALLD MYO16 MRTFA

2.41e-034661478EFO_0007841
DiseaseLymphoma, Follicular, Grade 2

CREBBP KMT2D

2.48e-03151472C1956132
DiseaseLymphoma, Follicular, Grade 3

CREBBP KMT2D

2.48e-03151472C1956131
DiseaseLymphoma, Follicular, Grade 1

CREBBP KMT2D

2.48e-03151472C1956130
DiseaseLymphoma, Large-Cell, Follicular

CREBBP KMT2D

2.48e-03151472C0079745
DiseaseLymphoma, Small Cleaved-Cell, Follicular

CREBBP KMT2D

2.48e-03151472C0079765
DiseaseLymphoma, Mixed-Cell, Follicular

CREBBP KMT2D

2.48e-03151472C0079758
Diseaseopen-angle glaucoma

THSD7A MAPT TRIOBP SVEP1 RERE

2.74e-031911475EFO_0004190
Diseaseneuroblastoma

CRIM1 LAMA5 ARHGEF40 GREB1

2.75e-031161474EFO_0000621
Diseasecentral nervous system disease (implicated_via_orthology)

SEC31B TAOK2

2.83e-03161472DOID:331 (implicated_via_orthology)
Diseasesystemic lupus erythematosus, COVID-19

MAPT KCP ITGAM

3.06e-03581473MONDO_0007915, MONDO_0100096
DiseaseMAJOR AFFECTIVE DISORDER 2

CUX2 TOM1

3.19e-03171472C1839839
Diseasecreatine kinase measurement

SNX13 MRTFA SAMD4A

3.21e-03591473EFO_0004534
DiseaseTourette syndrome, schizophrenia

ZNF536 RERE

3.58e-03181472EFO_0004895, MONDO_0005090
Diseaseoptic disc size measurement

ALX3 KIF6 TRIOBP RERE PDZD2

3.71e-032051475EFO_0004832
Diseasehair colour measurement

FRAS1 CUX2 NYAP2 TOM1 ATG2A SNX13 KMT2D NFATC1 MITF

3.80e-036151479EFO_0007822
Diseasebrain connectivity measurement

TBX15 KIF6 MAPT SEM1 TRIOBP RERE MYO16

4.02e-034001477EFO_0005210
Diseasemaximal midexpiratory flow rate

MYO16 SAMD4A

4.42e-03201472EFO_0004313
DiseaseLymphoma, Follicular

CREBBP KMT2D

4.42e-03201472C0024301
Diseaseobesity (implicated_via_orthology)

FAT4 ADAMTS4 MAPT ADAMTS9 AOC3

4.54e-032151475DOID:9970 (implicated_via_orthology)
Diseasehearing loss

KLHDC7B TRIOBP ITGAM

4.60e-03671473EFO_0004238
DiseaseSchizophrenia

CACNA1F PSD HTR4 ADNP2 GRIK5 PTPN21 ITGAM TET1 PITX3 KIF17 MYO16

4.81e-0388314711C0036341
Diseasealkaline phosphatase measurement

CUX2 MAPT SEM1 WDR81 KCP GRIK5 SNX13 NFATC1 RP1L1 PITX3 MITF KIF17

4.95e-03101514712EFO_0004533

Protein segments in the cluster

PeptideGeneStartEntry
PPLLPNGKALCHTTS

AZI2

286

Q9H6S1
PQCTPALNLTPSHPH

nan

126

P0DMU3
PCPSPLVTPTHALAP

C16orf86

251

Q6ZW13
QAPGPALTPSLLPTH

ELK1

346

P19419
SSPGPRPAPSHCSLA

ARHGEF40

996

Q8TER5
LQGSPGPCLASLHLP

ALX3

121

O95076
SGLPAHACAQLSPSP

ARID3C

271

A6NKF2
APAPPQSGSCDHPLL

FAM117A

246

Q9C073
ACPTPNPLSRHSPAP

FAT4

4691

Q6V0I7
GKDCSIHNPLPTSPP

ADAM11

706

O75078
HPLQPLPKSATSPAG

ARHGEF33

671

A8MVX0
QEGHASPCPPLQPVS

CCNI

361

Q14094
SQLPCPPVTQSPLHP

CREBBP

841

Q92793
PGGSTPDCPSLHPQQ

CUX2

1351

O14529
APPDSISLHQPCNPP

DMRTC1;

141

Q5HYR2
ISLHQPCNPPAPAGD

DMRTC1;

146

Q5HYR2
IPSEQHPGASASPPC

DLX2

216

Q07687
LSQTPHSQPPRPGTC

DAXX

706

Q9UER7
TSQPCPPAATHSLGL

FAM90A10

266

A6NDY2
PGPPVPTHLELTCSD

ATG2A

686

Q2TAZ0
PLDCRGSPHQLPTPV

ATXN7L2

626

Q5T6C5
SAPSAPAQPPCFHLA

ADNP2

281

Q6IQ32
SQLPHCPSVSPSAQP

AOC3

36

Q16853
PPDPCKQSPVHLAAG

ANKRD37

26

Q7Z713
APPTLAQAPIGLSPH

ANKRD63

301

C9JTQ0
PSQAFSSCHPGLPPE

FBXL19

266

Q6PCT2
PALPCAPPSVHLSAE

ISLR2

226

Q6UXK2
APPSAKASPHNPGSC

RIMBP3B

1221

A6NNM3
APPSAKASPHNPGSC

RIMBP3C

1221

A6NJZ7
TSQPCPPAATHSLGL

FAM90A7

266

A6NKC0
SPPIACQSPAHRPGA

ZFYVE28

361

Q9HCC9
NPGHCITDPPSLGPQ

CD6

541

P30203
EQAGTPPCSVLLPPH

CACNA1F

1761

O60840
TPQPCPPAATHSLGL

FAM90A23

266

A8MXZ1
LPEGSAPKPSPLHCL

KRBA1

601

A5PL33
TPQPCPPLSCGHQEL

FRAS1

126

Q86XX4
ALPAAPPVANSSLPC

KMT2C

3556

Q8NEZ4
PNPFQLHPLPEGCCT

GREB1

76

Q4ZG55
DSKPHPSVQCSPTPG

LGR6

536

Q9HBX8
VHPKPNSAPVAGPCS

MYO16

1616

Q9Y6X6
TSQPCPPAATHSLGL

FAM90A1

266

Q86YD7
PLGRPSLCLPPTSHT

KRT37

61

O76014
LLLDPHSPETGCPPL

LMAN1L

16

Q9HAT1
PCLSLGAPSLLPHPS

MESP2

316

Q0VG99
AVPHTPGLCTSLPDP

ELAPOR1

71

Q6UXG2
PLTLALPPAPPSSCH

KDM6B

601

O15054
LPPAPPSSCHQNTSG

KDM6B

606

O15054
STFHSLSPPGCRPPQ

MAPK8IP2

11

Q13387
TPQPCPPAATHSLGL

FAM90A22

266

A8MWA6
QPSALESDCPGPSHP

IBA57-DT

41

B1ANH7
TSQPCPPAATHSLGL

FAM90A14

266

P0C7W9
LGPHVLCAPPSPTLE

LENG9

406

Q96B70
GCPNPPSSPAHLPTQ

PDZD2

1606

O15018
PSSPAHLPTQAAICP

PDZD2

1611

O15018
TPPCLSTVAPPIHQG

NID1

916

P14543
CIPSHRVLGPPTSIP

FKBP15

1031

Q5T1M5
VSAPPSSSCPPGLEH

NFATC1

826

O95644
PACPPATGRPQHLPS

NFATC1

866

O95644
PQQPLCHSPGASLPP

MYRFL

146

Q96LU7
APAQPSSIPPCALVS

PHRF1

1481

Q9P1Y6
ILPSPCPSPHSQKQS

KIF6

751

Q6ZMV9
NSIPTPTASGFCPHP

KMT2E

1801

Q8IZD2
SPAVQLAPATPPIGH

MNT

476

Q99583
NQPAHPLLLTSPGPT

KIAA1549L

541

Q6ZVL6
PHPAPVVCSADPQLA

LMNTD2

41

Q8IXW0
TSQPCPPAATHSLGL

FAM90A17

266

P0DV74
LPRPCPTEQLSPSHP

LAMA5

1071

O15230
PAPVHCSPNSDESPL

NYAP2

341

Q9P242
SPVSSCPPELANHPD

DDX23

786

Q9BUQ8
TSQPCPPAATHSLGL

FAM90A16

266

P0DV73
QVHPQSPLCPLPGSA

ITGB4

1621

P16144
TSQPCPPAATHSLGL

FAM90A19

266

P0DV76
DPQSPNPPLLVHCSA

PTPN21

1096

Q16825
TLSACPPNPGLVSPS

OTOP2

456

Q7RTS6
TPTLPAVPLPANACG

MRGPRG

131

Q86SM5
PPLPSPGQASHCSSP

PALLD

826

Q8WX93
SAHLPLPLSLPGCPA

ACP4

341

Q9BZG2
PSPSALPICLHPAGI

PRSS36

691

Q5K4E3
TSQPCPPAATHSLGL

FAM90A8

266

A6NJQ4
PPTHHGSQVCRPPLL

GATA3

76

P23771
LTFGPDSRHCPQLPP

ADAMTS4

451

O75173
TINCPGTQPPSVHPC

ADAMTS9

1656

Q9P2N4
THCGLPGVPSSLSVP

ICE2

891

Q659A1
LCPLKHPSHQPPAST

C5orf60

201

A6NFR6
PLPSLVVCPPTLTGH

BTAF1

1326

O14981
SCGPLLLSHPPEASP

DMRTC2

151

Q8IXT2
TSPHQGASPPHICSP

CROCC2

381

H7BZ55
GASPPHICSPATLDP

CROCC2

386

H7BZ55
PHTPGPCQSSHLPST

FAM193B

301

Q96PV7
APAHPLSLPVANGPA

DGKI

146

O75912
QPHDSPSLLQCPLPS

BATF2

141

Q8N1L9
SPAAPACLAPLSHSP

FHOD3

516

Q2V2M9
ACQSPPAPHPTLITH

ILK

256

Q13418
ITCPVPACGNPTIHP

CRIM1

641

Q9NZV1
QCHPPATSPLVAAQP

HTR4

371

Q13639
ATPCGPSVQPSHQPL

BAHD1

286

Q8TBE0
LPCLHQPTHLPAPSG

AKNA

681

Q7Z591
SCHSALPIPATPPTQ

ATG9B

86

Q674R7
TPPTRPAPAPCHANT

B3GNT3

51

Q9Y2A9
AHPGPSSPCAQQLPV

MAPKBP1

1361

O60336
PSLPPGSLQPLLSCS

FAM98C

191

Q17RN3
ACNPPTDPGRKPLSH

DYNC1H1

2711

Q14204
LPAPAPLHCTTLGNT

KLHDC7B

526

Q96G42
APPSPHLLLGAPALC

ETV3L

136

Q6ZN32
PSGARPAAPTPCTHV

GRIK5

916

Q16478
TSQPCPPAATHSLGL

FAM90A5P

266

A8MXJ8
ISQPAPISPHLSGPA

CALCOCO1

576

Q9P1Z2
AVHGPPPAANLSPCQ

PITX3

281

O75364
PVEAPPLSPCTHNPL

MAP3K9

866

P80192
TPQPCPPAATHSLGL

FAM90A24P

266

P0C7X0
LHSVQCSPSPGPFKP

LGR5

536

O75473
LCPQHVGLPPPARTS

PARP6

236

Q2NL67
PPGLSCPLSNNSAIP

KIF17

976

Q9P2E2
LQEPHSPALPSSPPC

RUSC2

1436

Q8N2Y8
LAPSPSASPVCHPPG

STK11IP

736

Q8N1F8
QCEHSFLPPTSPGVP

SNX13

61

Q9Y5W8
PPNSMPSSPHCLTGA

SERGEF

321

Q9UGK8
CLLHPSADGTPFPAP

TPSG1

306

Q9NRR2
AKLAPGREPPSPCHS

PSD

491

A5PKW4
GPIPNTTQLCHIPCP

THSD7A

496

Q9UPZ6
PVSSCTPQHIGPAIP

LINC00869

156

P0C866
GASALPLCPSPAPHS

MAP3K21

911

Q5TCX8
APPSAKASPHNPGSC

RIMBP3

1221

Q9UFD9
GAVLCPPAPCQHPTQ

KCP

461

Q6ZWJ8
TSLPCPPAATHSLGL

FAM90A12P

266

A8MX19
ASAPLTTPHLETPPC

PRR36

771

Q9H6K5
TSQPCPPAATHSLGL

FAM90A9

266

A6NNJ1
TSQPCPPAATHSLGL

FAM90A13P

266

P0C7W8
LSPSCSPPTFHLAPN

TBX15

366

Q96SF7
TSQPCPPAATHSLGL

FAM90A26

266

D6RGX4
PSHSLCPGPPALASV

FGD1

306

P98174
PLSDPALAPHTCSPP

PRSS47P

326

A8MTI9
LPSPAPSLLCSLAQP

SLAIN1

106

Q8ND83
PPAPCPASSSILVNG

SIX5

311

Q8N196
LPGFQAVHCPAPSPV

ST6GAL2

511

Q96JF0
PPTHLRPCPASQLPG

TAOK2

931

Q9UL54
HLSPPVPSLGCSSPP

SPATA31E1

526

Q6ZUB1
STAPLSPPPSLVHCE

SEM1

91

Q6ZVN7
PNTGQCHLCLPPSEP

MUTYH

331

Q9UIF7
PAHGSAPTALCPPKL

PPP1R26

176

Q5T8A7
PACSLPVASQPPQHL

RERE

151

Q9P2R6
APSPLGTAVCPFSPH

RUSC1-AS1

111

Q66K80
FGLPSTPAHLVPQPC

SEC31B

401

Q9NQW1
SSLPHGLPPCAPDLQ

SKIV2L

41

Q15477
TTSPPQLLACGPTVH

ITGAM

96

P11215
IPCPDENHTSPPGST

SVEP1

341

Q4LDE5
TSQPCPPAATHSLGL

FAM90A15P

266

P0C7V4
TNHIDPCAVAPGPPS

MRTFA

606

Q969V6
PPSAAPQAILCHPSL

OS9

236

Q13438
QGPTPDVTASPPCHI

STRC

506

Q7RTU9
SPEPSQPPCAVCIGH

TRIOBP

1006

Q9H2D6
PDHPSLPCQPVLSSG

SPATA1

271

Q5VX52
AAGSPPCHSPELLQP

SP8

466

Q8IXZ3
AHPLTQPSSPPNQCA

TET1

1296

Q8NFU7
IHTTPICNPPLSSPG

CIART

261

Q8N365
LPPPASIACRVHAGP

MRPL19

26

P49406
HCSATPAPPPGRVSS

PIAS3

581

Q9Y6X2
SPSHSPNRSPCVPPA

INPP5J

351

Q15735
AGSSHPACFRPPPLL

nan

111

P0C880
SEVFPAQHPPPSGIC

TRAF3IP3

121

Q9Y228
PHSLPPPLTLHCNIT

UBE2Q2

46

Q8WVN8
PAHLLPTSSLPICPG

PP632

56

Q6XCG6
GCLFLPSLAPHNAPT

WDFY3

1056

Q8IZQ1
PPPGLTISNSCPANL

MITF

271

O75030
PPSHLGPECQPFISS

SPATA31A1

471

Q5TZJ5
AGSRTCSPAPIPPHT

RP1L1

766

Q8IWN7
RTLHPAPSPSLPPQC

TNS4

26

Q8IZW8
SGQHAAPLPAPPILS

TOM1

191

O60784
PLGTTSDPAAPPHRC

ZNF672

151

Q499Z4
NRPCLSPKHPTPGSS

MAPT

406

P10636
TSTLCPPANPHPQFG

TBXT

251

O15178
PQPSHSTPQASCPLP

TET3

371

O43151
CVPSNGLLHPPSASA

IGSF9

301

Q9P2J2
PPPHAQQAPLAACTL

ZNF536

226

O15090
HCLSAVPTPAPISAP

ZXDA

141

P98168
AVPGILPSSQPPISC

TMEM219

146

Q86XT9
QGPTPDVTASPPCHI

STRCP1

506

A6NGW2
SSLGQCHLKEIPPPP

TEX33

61

O43247
PLPCHLPDLQIPGTS

PLEKHG2

1096

Q9H7P9
GPCPPLSSGPLHLAQ

HIVEP2

1141

P31629
SPPTPAPQHSDLCLA

RIPOR1

761

Q6ZS17
PLSQRHSPAPQCPSP

TBKBP1

336

A7MCY6
SPLPPQHTCSALAPP

ZNF619

486

Q8N2I2
QHTCSALAPPGPPLS

ZNF619

491

Q8N2I2
PQCLPSDHAPLSPQS

SAMD4A

281

Q9UPU9
VSQGLPPPCPSQLLS

WDR81

851

Q562E7
HPALLLAPQESPSGP

ZNF692

471

Q9BU19
PLPPDPLCLHNSSLF

TLX2

246

O43763
PLAPAGVPCAFSPHS

WDR43

11

Q15061
TSQPCPPAATHSLGL

FAM90A18

266

P0DV75
EPQLCPRSEGPHLSP

KMT2D

731

O14686
TLACHPPLSPGPRAS

N4BP3

151

O15049