Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

GPBAR1 VIPR2 CYSLTR2 ADRA1B HTR1F KISS1R OR4K17 OR11H4 FFAR3 GPR42 OR6Q1 MRGPRE GPR85 MC1R OR4K5 CALCRL CRHR2 OR4L1 HRH3 OR11H6

7.55e-138846120GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPBAR1 VIPR2 CYSLTR2 ADRA1B HTR1F KISS1R EPHA6 OR4K17 OR11H4 FFAR3 GPR42 OR6Q1 MRGPRE GPR85 MC1R OR4K5 CALCRL SLC22A17 CRHR2 OR4L1 HRH3 OR11H6

2.76e-1113536122GO:0004888
GeneOntologyMolecularFunctiontransporter activity

SLC22A9 TRPC7 KCNU1 TRPM7 ATP13A1 ATP8A2 TRPC3 TRPC6 SLC22A10 SLC49A4 CYB561D1 KCNK5 SLC34A3 TMC5 SLC30A1 SLC23A2 ABCA9 SLC22A17 SLC16A10

4.70e-0912896119GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC22A9 TRPC7 KCNU1 TRPM7 ATP13A1 TRPC3 TRPC6 SLC22A10 SLC49A4 CYB561D1 KCNK5 SLC34A3 TMC5 SLC30A1 SLC23A2 ABCA9 SLC22A17 SLC16A10

7.86e-0911806118GO:0022857
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPC7 KCNU1 TRPM7 ATP13A1 TRPC3 TRPC6 KCNK5 SLC34A3 SLC30A1 SLC23A2

1.33e-064656110GO:0046873
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

VIPR2 CYSLTR2 KISS1R MC1R CALCRL CRHR2

3.21e-06133616GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

VIPR2 CYSLTR2 KISS1R MC1R CALCRL CRHR2

4.31e-06140616GO:0001653
GeneOntologyMolecularFunctionstore-operated calcium channel activity

TRPC7 TRPC3 TRPC6

5.85e-0612613GO:0015279
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

TRPC7 TRPC3 TRPC6

9.64e-0614613GO:0070679
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC22A9 ATP13A1 SLC22A10 CYB561D1 SLC34A3 SLC30A1 SLC23A2 ABCA9 SLC16A10

1.35e-05477619GO:0022804
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPC7 KCNU1 TRPM7 ATP13A1 TRPC3 TRPC6 KCNK5 SLC34A3 SLC30A1 SLC23A2

1.85e-056276110GO:0022890
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TRPC7 KCNU1 TRPM7 ATP13A1 TRPC3 TRPC6 KCNK5 SLC34A3 TMC5 SLC30A1 SLC23A2

2.46e-057936111GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPC7 KCNU1 TRPM7 ATP13A1 TRPC3 TRPC6 KCNK5 SLC34A3 SLC30A1 SLC23A2

3.01e-056646110GO:0008324
GeneOntologyMolecularFunctioncalcium/calmodulin-dependent protein kinase activity

CAMK2B CAMK2D CAMK2G

7.53e-0527613GO:0004683
GeneOntologyMolecularFunctionshort-chain fatty acid transmembrane transporter activity

SLC22A9 SLC22A10

9.13e-055612GO:0015636
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TRPC7 KCNU1 TRPM7 ATP13A1 TRPC3 TRPC6 KCNK5 SLC34A3 SLC30A1 SLC23A2

9.14e-057586110GO:0015318
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

ADRA1B HTR1F HRH3

2.66e-0441613GO:0008227
GeneOntologyMolecularFunctionhormone binding

VIPR2 MC1R CALCRL CRHR2

2.78e-04103614GO:0042562
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC22A9 SLC22A10 SLC34A3 SLC30A1 SLC23A2 SLC16A10

2.82e-04296616GO:0015291
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPC7 KCNU1 TRPM7 TRPC3 TRPC6 KCNK5 TMC5

4.84e-04459617GO:0005216
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

SLC22A9 SLC22A10

5.94e-0412612GO:0019534
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPC7 KCNU1 TRPM7 TRPC3 TRPC6 KCNK5

6.17e-04343616GO:0005261
GeneOntologyMolecularFunctionpeptide hormone binding

VIPR2 CALCRL CRHR2

6.36e-0455613GO:0017046
GeneOntologyMolecularFunctioncalcium channel activity

TRPC7 TRPM7 TRPC3 TRPC6

6.53e-04129614GO:0005262
GeneOntologyMolecularFunctionchannel activity

TRPC7 KCNU1 TRPM7 TRPC3 TRPC6 KCNK5 TMC5

1.07e-03525617GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPC7 KCNU1 TRPM7 TRPC3 TRPC6 KCNK5 TMC5

1.08e-03526617GO:0022803
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPC7 TRPM7 TRPC3 TRPC6

1.17e-03151614GO:0015085
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLC22A9 SLC22A10

1.36e-0318612GO:0015347
GeneOntologyMolecularFunctionamine binding

HTR1F HRH3

1.86e-0321612GO:0043176
GeneOntologyMolecularFunctionolfactory receptor activity

OR4K17 OR11H4 OR6Q1 OR4K5 OR4L1 OR11H6

1.99e-03431616GO:0004984
GeneOntologyMolecularFunctionG protein-coupled serotonin receptor activity

HTR1F HRH3

2.04e-0322612GO:0004993
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

SLC22A9 SLC22A10

2.23e-0323612GO:0015245
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC22A9 SLC22A10 SLC16A10

2.64e-0390613GO:0008028
GeneOntologyMolecularFunctionlipid transporter activity

SLC22A9 ATP8A2 SLC22A10 ABCA9

3.04e-03196614GO:0005319
GeneOntologyMolecularFunctioncalcium-activated cation channel activity

KCNU1 TRPC3

3.07e-0327612GO:0005227
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC22A9 SLC22A10 SLC23A2 SLC16A10

3.69e-03207614GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC22A9 SLC22A10 SLC23A2 SLC16A10

3.75e-03208614GO:0005342
GeneOntologyMolecularFunctionalcohol binding

TRPC7 TRPC3 TRPC6

3.76e-03102613GO:0043178
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

KCNU1 TRPC3

4.03e-0331612GO:0022839
GeneOntologyMolecularFunctionprotein serine kinase activity

HIPK3 TRPM7 CAMK2B CAMK2D CAMK2G

5.00e-03363615GO:0106310
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

ATP13A1 SLC30A1

8.00e-0344612GO:0046915
GeneOntologyMolecularFunctionion channel inhibitor activity

CAMK2D SLC30A1

9.46e-0348612GO:0008200
GeneOntologyMolecularFunctionprotein kinase activity

HIPK3 EPHA6 TRPM7 CAMK2B CAMK2D CAMK2G

9.84e-03600616GO:0004672
GeneOntologyMolecularFunctionABC-type transporter activity

ATP13A1 ABCA9

9.84e-0349612GO:0140359
GeneOntologyMolecularFunctionchannel inhibitor activity

CAMK2D SLC30A1

1.02e-0250612GO:0016248
GeneOntologyMolecularFunctiontransporter inhibitor activity

CAMK2D SLC30A1

1.06e-0251612GO:0141110
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

HIPK3 TRPM7 CAMK2B CAMK2D CAMK2G

1.16e-02446615GO:0004674
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC22A9 SLC22A10 SLC23A2 SLC16A10

1.23e-02293614GO:0008514
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP13A1 SLC34A3 SLC30A1 SLC23A2

1.35e-02301614GO:0022853
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

GPBAR1 VIPR2 CYSLTR2 ADRA1B HTR1F KISS1R OR4K17 OR11H4 CAMK2B FFAR3 GPR42 OR6Q1 MRGPRE GPR85 MC1R OR4K5 CALCRL CRHR2 OR4L1 HRH3 OR11H6

2.08e-1013956121GO:0007186
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC22A9 TRPC7 KCNU1 TRPM7 ATP13A1 CAMK2B CAMK2D CAMK2G TRPC3 TRPC6 SLC22A10 KCNK5 SLC34A3 CALCRL TMC5 SLC30A1 SLC23A2 SLC22A17 CRHR2 HRH3

1.15e-0913746120GO:0006811
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

GPBAR1 VIPR2 ADRA1B HTR1F FFAR3 GPR42 MC1R CALCRL CRHR2 HRH3

1.09e-082866110GO:0007188
GeneOntologyBiologicalProcessmetal ion transport

TRPC7 KCNU1 TRPM7 ATP13A1 CAMK2B CAMK2D CAMK2G TRPC3 TRPC6 KCNK5 SLC34A3 CALCRL SLC30A1 SLC23A2 SLC22A17 CRHR2

2.14e-0810006116GO:0030001
GeneOntologyBiologicalProcessmonoatomic cation transport

TRPC7 KCNU1 TRPM7 ATP13A1 CAMK2B CAMK2D CAMK2G TRPC3 TRPC6 KCNK5 SLC34A3 CALCRL SLC30A1 SLC23A2 SLC22A17 CRHR2

1.60e-0711576116GO:0006812
GeneOntologyBiologicalProcessregulation of norepinephrine secretion

FFAR3 GPR42 CRHR2 HRH3

9.86e-0726614GO:0014061
GeneOntologyBiologicalProcessnorepinephrine secretion

FFAR3 GPR42 CRHR2 HRH3

1.34e-0628614GO:0048243
GeneOntologyBiologicalProcesscalcium ion transport

TRPC7 TRPM7 CAMK2B CAMK2D CAMK2G TRPC3 TRPC6 CALCRL SLC30A1 CRHR2

2.24e-065096110GO:0006816
GeneOntologyBiologicalProcessnorepinephrine transport

FFAR3 GPR42 CRHR2 HRH3

4.74e-0638614GO:0015874
GeneOntologyBiologicalProcesspositive regulation of acute inflammatory response to non-antigenic stimulus

FFAR3 GPR42

2.58e-053612GO:0002879
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

HTR1F MC1R CALCRL HRH3

3.18e-0561614GO:0007187
GeneOntologyBiologicalProcesshormone transport

SLC22A9 KISS1R FFAR3 GPR42 CAMK2G VAMP7 CRHR2 SLC16A10

3.87e-05432618GO:0009914
GeneOntologyBiologicalProcessregulation of heart rate

ADRA1B FFAR3 CAMK2D GPR42 CRHR2

3.98e-05129615GO:0002027
GeneOntologyBiologicalProcessregulation of calcium ion transport

CAMK2B CAMK2D CAMK2G TRPC3 TRPC6 SLC30A1 CRHR2

4.57e-05323617GO:0051924
GeneOntologyBiologicalProcessregulation of catecholamine secretion

FFAR3 GPR42 CRHR2 HRH3

4.62e-0567614GO:0050433
GeneOntologyBiologicalProcessregulation of acute inflammatory response to non-antigenic stimulus

FFAR3 GPR42

5.14e-054612GO:0002877
GeneOntologyBiologicalProcesschemical homeostasis

ADRA1B TRPC7 TRPM7 ATP13A1 FFAR3 CAMK2D GPR42 TRPC3 TRPC6 SLC34A3 SLC30A1 SLC22A17 CRHR2

5.94e-0512496113GO:0048878
GeneOntologyBiologicalProcessorganic cation transport

FFAR3 GPR42 CRHR2 HRH3 SLC16A10

6.94e-05145615GO:0015695
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

TRPC7 KCNU1 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 KCNK5 SLC34A3 SLC30A1 SLC23A2

7.22e-059226111GO:0098662
GeneOntologyBiologicalProcessinorganic ion homeostasis

TRPC7 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC34A3 SLC30A1 SLC22A17

8.33e-05622619GO:0098771
GeneOntologyBiologicalProcessacute inflammatory response to non-antigenic stimulus

FFAR3 GPR42

8.55e-055612GO:0002525
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

TRPC7 KCNU1 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 KCNK5 SLC34A3 TMC5 SLC30A1 SLC23A2

8.73e-0511156112GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

TRPC7 KCNU1 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 KCNK5 SLC34A3 SLC30A1 SLC23A2

8.74e-059426111GO:0098655
GeneOntologyBiologicalProcesscatecholamine secretion

FFAR3 GPR42 CRHR2 HRH3

8.81e-0579614GO:0050432
GeneOntologyBiologicalProcesssignal release

KISS1R FFAR3 GPR42 CAMK2G VAMP7 SLC30A1 CRHR2 HRH3 SLC16A10

1.20e-04653619GO:0023061
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

HTR1F FFAR3 GPR42 HRH3

1.23e-0486614GO:0007193
GeneOntologyBiologicalProcesspositive regulation of neuronal action potential

FFAR3 GPR42

1.28e-046612GO:1904457
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

TRPC7 KCNU1 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 KCNK5 SLC34A3 SLC30A1 SLC23A2

1.72e-0410176111GO:0098660
GeneOntologyBiologicalProcesscatecholamine transport

FFAR3 GPR42 CRHR2 HRH3

1.88e-0496614GO:0051937
GeneOntologyBiologicalProcessintracellular chemical homeostasis

TRPC7 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC34A3 SLC30A1 SLC22A17 CRHR2

2.08e-048666110GO:0055082
GeneOntologyBiologicalProcesshormone secretion

KISS1R FFAR3 GPR42 CAMK2G VAMP7 CRHR2 SLC16A10

2.34e-04420617GO:0046879
GeneOntologyBiologicalProcessregulation of dendrite morphogenesis

CAMK2B TRPC6 VAMP7 SLC30A1

2.46e-04103614GO:0048814
GeneOntologyBiologicalProcessregulation of monoatomic ion transport

CAMK2B CAMK2D CAMK2G TRPC3 TRPC6 SLC30A1 CRHR2 HRH3

2.85e-04577618GO:0043269
GeneOntologyBiologicalProcessregulation of system process

ADRA1B CAMK2B FFAR3 CAMK2D GPR42 CAMK2G TRPC3 CALCRL CRHR2

2.88e-04734619GO:0044057
GeneOntologyBiologicalProcessregulation of relaxation of cardiac muscle

CAMK2D CAMK2G

3.06e-049612GO:1901897
GeneOntologyBiologicalProcessregulation of heart rate by chemical signal

FFAR3 GPR42

3.06e-049612GO:0003062
GeneOntologyBiologicalProcessregulation of muscle system process

ADRA1B CAMK2B CAMK2D CAMK2G TRPC3 CALCRL

3.43e-04317616GO:0090257
GeneOntologyBiologicalProcesssingle fertilization

TRPC7 CAMK2B TRPC3 TRPC6 LHFPL2

3.82e-04209615GO:0007338
GeneOntologyBiologicalProcessmonoamine transport

FFAR3 GPR42 CRHR2 HRH3

3.87e-04116614GO:0015844
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

TRPC7 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC30A1 SLC22A17

4.18e-04611618GO:0030003
GeneOntologyBiologicalProcessnegative regulation of secretion by cell

FFAR3 GPR42 SLC30A1 CRHR2 HRH3

4.26e-04214615GO:1903531
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

TRPC7 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC30A1 SLC22A17

4.71e-04622618GO:0006873
GeneOntologyBiologicalProcessregulation of amine transport

FFAR3 GPR42 CRHR2 HRH3

5.14e-04125614GO:0051952
GeneOntologyBiologicalProcessregulation of serotonin secretion

CRHR2 HRH3

5.57e-0412612GO:0014062
GeneOntologyBiologicalProcesscellular homeostasis

TRPC7 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC34A3 SLC30A1 SLC22A17 CRHR2

5.60e-049816110GO:0019725
GeneOntologyBiologicalProcessregulation of metal ion transport

CAMK2B CAMK2D CAMK2G TRPC3 TRPC6 SLC30A1 CRHR2

6.11e-04493617GO:0010959
GeneOntologyBiologicalProcessregulation of muscle adaptation

CAMK2B CAMK2D CAMK2G TRPC3

6.49e-04133614GO:0043502
GeneOntologyBiologicalProcesspositive regulation of transmission of nerve impulse

FFAR3 GPR42

6.57e-0413612GO:0051971
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

TRPC7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC30A1

6.61e-04359616GO:0006874
GeneOntologyBiologicalProcessregulation of blood pressure

ADRA1B FFAR3 GPR42 CRHR2 HRH3

6.77e-04237615GO:0008217
GeneOntologyBiologicalProcessregulation of protein localization to membrane

CAMK2B CAMK2D CAMK2G VAMP7 SLC30A1

6.77e-04237615GO:1905475
GeneOntologyBiologicalProcessnegative regulation of secretion

FFAR3 GPR42 SLC30A1 CRHR2 HRH3

7.03e-04239615GO:0051048
GeneOntologyBiologicalProcessamine transport

FFAR3 GPR42 CRHR2 HRH3

7.25e-04137614GO:0015837
GeneOntologyBiologicalProcessnegative regulation of insulin secretion

FFAR3 GPR42 CRHR2

8.22e-0462613GO:0046676
GeneOntologyBiologicalProcessregulation of heart contraction

ADRA1B FFAR3 CAMK2D GPR42 CRHR2

8.45e-04249615GO:0008016
GeneOntologyBiologicalProcessregulation of hormone levels

SLC22A9 KISS1R FFAR3 GPR42 CAMK2G VAMP7 CRHR2 SLC16A10

8.76e-04684618GO:0010817
GeneOntologyBiologicalProcessregulation of neuronal action potential

FFAR3 GPR42

8.81e-0415612GO:0098908
GeneOntologyBiologicalProcesscalcium ion homeostasis

TRPC7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC30A1

1.00e-03389616GO:0055074
GeneOntologyBiologicalProcessregulation of dendrite development

CAMK2B TRPC6 VAMP7 SLC30A1

1.02e-03150614GO:0050773
GeneOntologyBiologicalProcesspositive regulation of dendrite morphogenesis

CAMK2B VAMP7 SLC30A1

1.03e-0367613GO:0050775
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

TRPC7 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC30A1 SLC22A17

1.06e-03705618GO:0055080
GeneOntologyBiologicalProcessfertilization

TRPC7 CAMK2B TRPC3 TRPC6 LHFPL2

1.08e-03263615GO:0009566
GeneOntologyBiologicalProcessmuscle system process

ADRA1B CAMK2B ATP8A2 CAMK2D CAMK2G TRPC3 CALCRL

1.12e-03547617GO:0003012
GeneOntologyBiologicalProcesspositive regulation of cell morphogenesis

CAMK2B VAMP7 SLC30A1

1.12e-0369613GO:0010770
GeneOntologyBiologicalProcessnegative regulation of blood pressure

FFAR3 GPR42 HRH3

1.17e-0370613GO:0045776
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

TRPC7 TRPM7 ATP13A1 CAMK2D TRPC3 TRPC6 SLC30A1 SLC22A17

1.19e-03717618GO:0050801
GeneOntologyBiologicalProcessdetection of stimulus

OR4K17 OR11H4 ATP8A2 OR6Q1 TRPC3 OR4K5 OR4L1 OR11H6

1.24e-03722618GO:0051606
GeneOntologyBiologicalProcesspositive regulation of action potential

FFAR3 GPR42

1.28e-0318612GO:0045760
GeneOntologyBiologicalProcessstriated muscle adaptation

CAMK2B CAMK2G TRPC3

1.32e-0373613GO:0014888
GeneOntologyBiologicalProcessnegative regulation of peptide hormone secretion

FFAR3 GPR42 CRHR2

1.32e-0373613GO:0090278
GeneOntologyBiologicalProcessfeeding behavior

ATP8A2 MC1R CRHR2 HRH3

1.35e-03162614GO:0007631
GeneOntologyBiologicalProcessmuscle adaptation

CAMK2B CAMK2D CAMK2G TRPC3

1.41e-03164614GO:0043500
GeneOntologyBiologicalProcessregulation of relaxation of muscle

CAMK2D CAMK2G

1.42e-0319612GO:1901077
GeneOntologyBiologicalProcessserotonin secretion

CRHR2 HRH3

1.42e-0319612GO:0001820
GeneOntologyBiologicalProcessnegative regulation of peptide secretion

FFAR3 GPR42 CRHR2

1.43e-0375613GO:0002792
GeneOntologyBiologicalProcessregulation of skeletal muscle adaptation

CAMK2B CAMK2G

1.58e-0320612GO:0014733
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR4K17 OR11H4 ATP8A2 OR6Q1 OR4K5 OR4L1 OR11H6

1.60e-03582617GO:0050906
GeneOntologyBiologicalProcessnegative regulation of monoatomic ion transport

CAMK2D SLC30A1 CRHR2 HRH3

1.65e-03171614GO:0043271
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR4K17 OR11H4 OR6Q1 OR4K5 OR4L1 OR11H6

1.71e-03432616GO:0050911
GeneOntologyBiologicalProcessrelaxation of cardiac muscle

CAMK2D CAMK2G

1.74e-0321612GO:0055119
GeneOntologyBiologicalProcessnegative regulation of calcium ion import

SLC30A1 CRHR2

1.74e-0321612GO:0090281
GeneOntologyBiologicalProcessregulation of action potential

FFAR3 CAMK2D GPR42

1.78e-0381613GO:0098900
GeneOntologyBiologicalProcessheart contraction

ADRA1B FFAR3 CAMK2D GPR42 CRHR2

1.87e-03298615GO:0060047
GeneOntologyBiologicalProcessexport from cell

KISS1R FFAR3 GPR42 CAMK2G VAMP7 KCNK5 SLC30A1 CRHR2 HRH3 SLC16A10

1.91e-0311536110GO:0140352
GeneOntologyBiologicalProcessregulation of cytosolic calcium ion concentration

TRPC7 TRPC3 TRPC6

1.98e-0384613GO:0051480
GeneOntologyBiologicalProcessG protein-coupled serotonin receptor signaling pathway

HTR1F HRH3

2.09e-0323612GO:0098664
GeneOntologyBiologicalProcessregulation of neuron projection development

CAMK2B ATP8A2 CAMK2G TRPC6 VAMP7 SPART SLC30A1

2.13e-03612617GO:0010975
GeneOntologyBiologicalProcessheart process

ADRA1B FFAR3 CAMK2D GPR42 CRHR2

2.19e-03309615GO:0003015
GeneOntologyBiologicalProcessneuron projection morphogenesis

EPHA6 CAMK2B ATP8A2 TRPC6 VAMP7 SPART SLC30A1 SLC23A2

2.40e-03802618GO:0048812
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

GPBAR1 ADRA1B MC1R CALCRL

2.46e-03191614GO:0007189
GeneOntologyBiologicalProcesssensory perception of smell

OR4K17 OR11H4 OR6Q1 OR4K5 OR4L1 OR11H6

2.48e-03465616GO:0007608
GeneOntologyBiologicalProcessregulation of MAPK cascade

HIPK3 TBC1D10C GPBAR1 CYSLTR2 ADRA1B KISS1R CAMK2D CRHR2

2.65e-03815618GO:0043408
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

EPHA6 CAMK2B ATP8A2 TRPC6 VAMP7 SPART SLC30A1 SLC23A2

2.73e-03819618GO:0120039
GeneOntologyBiologicalProcessregulation of blood circulation

ADRA1B FFAR3 CAMK2D GPR42 CRHR2

2.76e-03326615GO:1903522
GeneOntologyBiologicalProcessdendrite morphogenesis

CAMK2B TRPC6 VAMP7 SLC30A1

2.81e-03198614GO:0048813
GeneOntologyBiologicalProcesscell projection morphogenesis

EPHA6 CAMK2B ATP8A2 TRPC6 VAMP7 SPART SLC30A1 SLC23A2

2.88e-03826618GO:0048858
GeneOntologyBiologicalProcessblood circulation

ADRA1B FFAR3 CAMK2D GPR42 SLC23A2 CRHR2 HRH3

2.93e-03648617GO:0008015
GeneOntologyCellularComponentcalcium- and calmodulin-dependent protein kinase complex

CAMK2B CAMK2D CAMK2G

2.35e-075613GO:0005954
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

CAMK2B CAMK2D CAMK2G

3.07e-0445613GO:0033017
GeneOntologyCellularComponentvaricosity

TRPM7 CRHR2

8.58e-0415612GO:0043196
MousePhenoabnormal sympathetic neuron innervation pattern

FFAR3 GPR42

3.46e-053482MP:0009284
MousePhenoabnormal sympathetic neuron physiology

FFAR3 GPR42

6.90e-054482MP:0009253
Domain7tm_1

GPBAR1 CYSLTR2 ADRA1B HTR1F KISS1R OR4K17 OR11H4 FFAR3 GPR42 OR6Q1 MRGPRE GPR85 MC1R OR4K5 OR4L1 HRH3 OR11H6

3.19e-116776117PF00001
DomainG_PROTEIN_RECEP_F1_1

GPBAR1 CYSLTR2 ADRA1B HTR1F KISS1R OR4K17 OR11H4 FFAR3 GPR42 OR6Q1 MRGPRE GPR85 MC1R OR4K5 OR4L1 HRH3 OR11H6

3.84e-116856117PS00237
DomainG_PROTEIN_RECEP_F1_2

GPBAR1 CYSLTR2 ADRA1B HTR1F KISS1R OR4K17 OR11H4 FFAR3 GPR42 OR6Q1 MRGPRE GPR85 MC1R OR4K5 OR4L1 HRH3 OR11H6

4.40e-116916117PS50262
DomainGPCR_Rhodpsn

GPBAR1 CYSLTR2 ADRA1B HTR1F KISS1R OR4K17 OR11H4 FFAR3 GPR42 OR6Q1 MRGPRE GPR85 MC1R OR4K5 OR4L1 HRH3 OR11H6

4.50e-116926117IPR000276
DomainGPCR_Rhodpsn_7TM

GPBAR1 CYSLTR2 ADRA1B HTR1F KISS1R OR4K17 OR11H4 FFAR3 OR6Q1 MRGPRE GPR85 MC1R OR4K5 OR4L1 HRH3 OR11H6

2.84e-106706116IPR017452
DomainCaMKII_AD

CAMK2B CAMK2D CAMK2G

1.32e-074613PF08332
DomainCa/CaM-dep_prot_kinase-assoc

CAMK2B CAMK2D CAMK2G

1.32e-074613IPR013543
DomainTRP_dom

TRPC7 TRPC3 TRPC6

6.58e-076613IPR013555
DomainTRP_2

TRPC7 TRPC3 TRPC6

6.58e-076613PF08344
DomainTRPC_channel

TRPC7 TRPC3 TRPC6

1.15e-067613IPR002153
DomainTRP_channel

TRPC7 TRPC3 TRPC6

5.37e-0611613IPR004729
Domain-

CAMK2B CAMK2D CAMK2G

9.26e-06136133.10.450.50
DomainNTF2-like_dom

CAMK2B CAMK2D CAMK2G

1.47e-0515613IPR032710
DomainMFS

SLC22A9 SLC22A10 SLC49A4 SLC22A17 SLC16A10

2.71e-05108615PS50850
DomainIon_trans_dom

TRPC7 KCNU1 TRPM7 TRPC3 TRPC6

3.51e-05114615IPR005821
DomainIon_trans

TRPC7 KCNU1 TRPM7 TRPC3 TRPC6

3.51e-05114615PF00520
DomainGPR40-rel_orph

FFAR3 GPR42

6.27e-054612IPR013312
DomainHormR

VIPR2 CALCRL CRHR2

7.24e-0525613SM00008
DomainMFS_dom

SLC22A9 SLC22A10 SLC49A4 SLC22A17 SLC16A10

7.60e-05134615IPR020846
DomainHRM

VIPR2 CALCRL CRHR2

1.02e-0428613PF02793
DomainMFS

SLC22A9 SLC22A10 SLC22A17 SLC16A10

1.17e-0477614IPR011701
DomainMFS_1

SLC22A9 SLC22A10 SLC22A17 SLC16A10

1.17e-0477614PF07690
DomainGPCR_2_secretin-like_CS

VIPR2 CALCRL CRHR2

1.85e-0434613IPR017983
DomainG_PROTEIN_RECEP_F2_1

VIPR2 CALCRL CRHR2

3.00e-0440613PS00649
DomainG_PROTEIN_RECEP_F2_3

VIPR2 CALCRL CRHR2

3.00e-0440613PS50227
DomainGPCR_2_extracellular_dom

VIPR2 CALCRL CRHR2

3.00e-0440613IPR001879
DomainG_PROTEIN_RECEP_F2_2

VIPR2 CALCRL CRHR2

5.82e-0450613PS00650
Domain7tm_2

VIPR2 CALCRL CRHR2

5.82e-0450613PF00002
DomainGPCR_2-like

VIPR2 CALCRL CRHR2

9.94e-0460613IPR017981
DomainGPCR_2_secretin-like

VIPR2 CALCRL CRHR2

9.94e-0460613IPR000832
DomainG_PROTEIN_RECEP_F2_4

VIPR2 CALCRL CRHR2

1.04e-0361613PS50261
DomainCa/CaM-dep_Ca-dep_prot_Kinase

CAMK2B CAMK2D CAMK2G

1.49e-0369613IPR020636
DomainOlfact_rcpt

OR4K17 OR11H4 OR6Q1 OR4K5 OR4L1 OR11H6

1.75e-03393616IPR000725
Domain-

ATP13A1 ATP8A2

4.89e-03326122.70.150.10
Domain-

ATP13A1 ATP8A2

4.89e-03326123.40.1110.10
DomainATPase_P-typ_cyto_domN

ATP13A1 ATP8A2

5.83e-0335612IPR023299
Domain7TM_GPCR_Srsx

ADRA1B HTR1F MC1R

5.87e-03112613SM01381
DomainSugar_tr

SLC22A10 SLC22A17

6.15e-0336612PF00083
DomainMFS_sugar_transport-like

SLC22A10 SLC22A17

6.15e-0336612IPR005828
DomainATPase_P-typ_P_site

ATP13A1 ATP8A2

6.15e-0336612IPR018303
DomainP_typ_ATPase

ATP13A1 ATP8A2

6.15e-0336612IPR001757
DomainATPASE_E1_E2

ATP13A1 ATP8A2

6.15e-0336612PS00154
DomainATPase_P-typ_transduc_dom_A

ATP13A1 ATP8A2

6.49e-0337612IPR008250
DomainE1-E2_ATPase

ATP13A1 ATP8A2

6.49e-0337612PF00122
DomainProtein_kinase_ATP_BS

HIPK3 EPHA6 CAMK2B CAMK2D CAMK2G

7.87e-03379615IPR017441
DomainKinase-like_dom

HIPK3 EPHA6 TRPM7 CAMK2B CAMK2D CAMK2G

8.36e-03542616IPR011009
PathwayWP_GPCRS_NONODORANT

GPBAR1 VIPR2 CYSLTR2 ADRA1B HTR1F KISS1R FFAR3 GPR42 MC1R CALCRL CRHR2 HRH3

7.89e-112664912MM15843
PathwayREACTOME_SIGNALING_BY_GPCR

GPBAR1 VIPR2 CYSLTR2 ADRA1B TRPC7 HTR1F KISS1R CAMK2B FFAR3 CAMK2D CAMK2G TRPC3 TRPC6 MC1R CALCRL CRHR2 HRH3

8.55e-117024917M746
PathwayREACTOME_SIGNALING_BY_GPCR

GPBAR1 VIPR2 CYSLTR2 ADRA1B TRPC7 HTR1F KISS1R FFAR3 GPR42 TRPC3 TRPC6 MC1R CALCRL CRHR2 HRH3

2.59e-096464915MM14962
PathwayREACTOME_ION_CHANNEL_TRANSPORT

TRPC7 TRPM7 ATP13A1 CAMK2B ATP8A2 CAMK2D CAMK2G TRPC3 TRPC6

8.03e-09176499MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

TRPC7 TRPM7 ATP13A1 CAMK2B ATP8A2 CAMK2D CAMK2G TRPC3 TRPC6

1.13e-08183499M997
PathwayREACTOME_GPCR_LIGAND_BINDING

GPBAR1 VIPR2 CYSLTR2 ADRA1B HTR1F KISS1R FFAR3 GPR42 MC1R CALCRL CRHR2 HRH3

1.85e-084304912MM15160
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPC7 TRPM7 ATP13A1 CAMK2B ATP8A2 CAMK2D CAMK2G TRPC3 TRPC6 SLC34A3 SLC30A1 ABCA9 SLC22A17 SLC16A10

4.62e-086814914MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPC7 TRPM7 ATP13A1 CAMK2B ATP8A2 CAMK2D CAMK2G TRPC3 TRPC6 SLC34A3 SLC30A1 ABCA9 SLC22A17 SLC16A10

1.21e-077364914M27287
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

VIPR2 CYSLTR2 ADRA1B HTR1F KISS1R MC1R CALCRL CRHR2 HRH3

3.40e-07272499M13380
PathwayREACTOME_GPCR_LIGAND_BINDING

GPBAR1 VIPR2 CYSLTR2 ADRA1B HTR1F KISS1R FFAR3 MC1R CALCRL CRHR2 HRH3

4.02e-074634911M507
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

CYSLTR2 ADRA1B TRPC7 KISS1R FFAR3 GPR42 TRPC3 TRPC6

5.67e-07210498MM15043
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP13A1 CAMK2B ATP8A2 CAMK2D CAMK2G

1.26e-0655495M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP13A1 CAMK2B ATP8A2 CAMK2D CAMK2G

1.50e-0657495MM15643
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

GPBAR1 CYSLTR2 ADRA1B HTR1F KISS1R FFAR3 GPR42 MC1R HRH3

1.84e-06333499MM14963
PathwayREACTOME_TRP_CHANNELS

TRPC7 TRPM7 TRPC3 TRPC6

2.48e-0628494MM14943
PathwayREACTOME_TRP_CHANNELS

TRPC7 TRPM7 TRPC3 TRPC6

2.48e-0628494M27241
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

CYSLTR2 ADRA1B HTR1F FFAR3 GPR42 GPR85 MC1R HRH3

2.82e-06260498M39397
PathwayREACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN_1_SIGNALING

TRPC7 TRPC3 TRPC6

4.66e-0610493M27330
PathwayREACTOME_CAMK_IV_MEDIATED_PHOSPHORYLATION_OF_CREB

CAMK2B CAMK2D CAMK2G

4.66e-0610493M26910
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR4K17 OR11H4 CAMK2B CAMK2D CAMK2G OR6Q1 OR4K5 OR4L1 OR11H6

6.54e-06389499M14091
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

CYSLTR2 ADRA1B TRPC7 KISS1R FFAR3 TRPC3 TRPC6

9.22e-06217497M18437
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC7 TRPC3 TRPC6

1.10e-0513493MM14553
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

1.40e-0514493M47386
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

1.40e-0514493M47388
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

GPBAR1 CYSLTR2 ADRA1B HTR1F KISS1R FFAR3 MC1R HRH3

1.62e-05330498M18334
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

GPBAR1 VIPR2 CYSLTR2 MC1R CALCRL CRHR2

1.63e-05157496M4904
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

1.74e-0515493M47385
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

TRPC7 TRPC3 TRPC6

2.14e-0516493M26945
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PLCG_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

2.59e-0517493M47387
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_CAMK_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

3.68e-0519493M47957
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

CAMK2B CAMK2D CAMK2G

3.68e-0519493MM15473
PathwayREACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR

CAMK2B CAMK2D CAMK2G

4.32e-0520493M17670
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2B CAMK2D CAMK2G

5.02e-0521493M838
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

CAMK2B CAMK2D CAMK2G

5.02e-0521493M27944
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

CAMK2B CAMK2D CAMK2G

5.80e-0522493MM15104
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_MECP2

CAMK2B CAMK2D CAMK2G TRPC3

6.60e-0563494M27862
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP2B3_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

6.66e-0523493M47512
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CAMK2B CAMK2D CAMK2G

6.66e-0523493MM14953
PathwayREACTOME_LONG_TERM_POTENTIATION

CAMK2B CAMK2D CAMK2G

6.66e-0523493M27949
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

VIPR2 CALCRL CRHR2

7.59e-0524493MM15992
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_CACNA1D_H_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

7.59e-0524493M47509
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

VIPR2 CALCRL CRHR2

7.59e-0524493M39643
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KCNJ5_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

8.60e-0525493M47510
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_ATP1A1_TO_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

8.60e-0525493M47511
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

TRPC7 TRPC3 TRPC6

8.60e-0525493MM14511
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

TRPC7 TRPC3 TRPC6

1.09e-0427493M12123
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

TRPC7 TRPC3 TRPC6

1.09e-0427493MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

TRPC7 TRPC3 TRPC6

1.22e-0428493M924
PathwayKEGG_MEDICUS_REFERENCE_ANGIOTENSIN_ALDOSTERONE_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

1.22e-0428493M47508
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

CAMK2B CAMK2D CAMK2G

1.22e-0428493M837
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

GPBAR1 VIPR2 MC1R CALCRL CRHR2

1.33e-04143495MM15055
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

CAMK2B CAMK2D CAMK2G

1.35e-0429493MM15028
PathwayREACTOME_TRAFFICKING_OF_AMPA_RECEPTORS

CAMK2B CAMK2D CAMK2G

1.66e-0431493M7223
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

CAMK2B CAMK2D CAMK2G

1.82e-0432493M27455
PathwayREACTOME_REGULATION_OF_MECP2_EXPRESSION_AND_ACTIVITY

CAMK2B CAMK2D CAMK2G

1.82e-0432493M27900
PathwayWP_DISRUPTION_OF_POSTSYNAPTIC_SIGNALING_BY_CNV

CAMK2B CAMK2D CAMK2G

2.00e-0433493M39875
PathwayREACTOME_RAF_ACTIVATION

CAMK2B CAMK2D CAMK2G

2.19e-0434493M27556
PathwayREACTOME_ACTIVATION_OF_NMDA_RECEPTORS_AND_POSTSYNAPTIC_EVENTS

CAMK2B CAMK2D CAMK2G

2.39e-0435493MM15109
PathwayREACTOME_RAF_ACTIVATION

CAMK2B CAMK2D CAMK2G

2.39e-0435493MM15271
PathwayREACTOME_CA_DEPENDENT_EVENTS

CAMK2B CAMK2D CAMK2G

2.82e-0437493M749
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CAMK2B CAMK2D CAMK2G

3.06e-0438493M27255
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_CAMKII_CAMKK_CAMKIV_CASCASDE

CAMK2B CAMK2G

3.27e-048492M10546
PathwayPID_IFNG_PATHWAY

CAMK2B CAMK2D CAMK2G

3.56e-0440493M161
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CYSLTR2 ADRA1B CAMK2B CAMK2D CAMK2G

3.69e-04178495M2890
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TRPC7 TRPM7 TRPC3 TRPC6

3.81e-0499494MM14910
PathwayREACTOME_DAG_AND_IP3_SIGNALING

CAMK2B CAMK2D CAMK2G

3.83e-0441493M512
PathwayKEGG_MELANOGENESIS

CAMK2B CAMK2D CAMK2G MC1R

4.11e-04101494M7761
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

ADRA1B HTR1F HRH3

4.12e-0442493M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

ADRA1B HTR1F HRH3

4.12e-0442493MM14971
PathwayREACTOME_CARDIAC_CONDUCTION

CAMK2B CAMK2D CAMK2G KCNK5

4.42e-04103494MM15196
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

CAMK2B CAMK2D CAMK2G

4.73e-0444493M27934
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

CAMK2B CAMK2D CAMK2G

4.73e-0444493M39845
PathwayREACTOME_NETRIN_1_SIGNALING

TRPC7 TRPC3 TRPC6

4.73e-0444493M875
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TRPC7 TRPM7 TRPC3 TRPC6

4.93e-04106494M27200
PathwayREACTOME_SIGNALING_BY_MODERATE_KINASE_ACTIVITY_BRAF_MUTANTS

CAMK2B CAMK2D CAMK2G

5.05e-0445493M27623
PathwayWP_NOCGMPPKG_MEDIATED_NEUROPROTECTION

CAMK2B CAMK2D CAMK2G

5.75e-0447493M39531
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2B CAMK2D CAMK2G

8.64e-0454493MM15202
PathwayREACTOME_ION_HOMEOSTASIS

CAMK2B CAMK2D CAMK2G

8.64e-0454493M27460
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

CAMK2B CAMK2D CAMK2G

8.64e-0454493M26911
PathwayREACTOME_CARDIAC_CONDUCTION

CAMK2B CAMK2D CAMK2G KCNK5

1.06e-03130494M27454
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

VIPR2 CALCRL CRHR2

1.18e-0360493MM14964
PathwayREACTOME_SIGNALING_BY_BRAF_AND_RAF1_FUSIONS

CAMK2B CAMK2D CAMK2G

1.48e-0365493M38994
PathwayKEGG_GLIOMA

CAMK2B CAMK2D CAMK2G

1.48e-0365493M1835
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

ADRA1B CAMK2B CAMK2D CAMK2G

1.67e-03147494MM15854
PathwayKEGG_LONG_TERM_POTENTIATION

CAMK2B CAMK2D CAMK2G

1.83e-0370493M3115
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR11H4 OR4L1 OR11H6

1.83e-0370493MM14984
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

ADRA1B CAMK2B CAMK2D CAMK2G

1.84e-03151494M39329
PathwayWP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY

CAMK2D TRPC3 TRPC6

2.15e-0374493M48080
PathwayWP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3

CAMK2B CAMK2D CAMK2G

2.24e-0375493M39568
PathwayREACTOME_PLATELET_HOMEOSTASIS

TRPC7 TRPC3 TRPC6

2.32e-0376493MM15051
PathwayREACTOME_MUSCLE_CONTRACTION

CAMK2B CAMK2D CAMK2G KCNK5

2.55e-03165494MM15026
PathwayREACTOME_ONCOGENIC_MAPK_SIGNALING

CAMK2B CAMK2D CAMK2G

2.88e-0382493M27626
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR4K17 OR11H4 OR6Q1 OR4K5 OR4L1 OR11H6

3.08e-03417496M4072
PathwayREACTOME_PLATELET_HOMEOSTASIS

TRPC7 TRPC3 TRPC6

3.30e-0386493M916
PathwayKEGG_ERBB_SIGNALING_PATHWAY

CAMK2B CAMK2D CAMK2G

3.41e-0387493M12467
PathwayREACTOME_OPIOID_SIGNALLING

CAMK2B CAMK2D CAMK2G

3.75e-0390493M6467
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADRA1B HTR1F OR11H4 MC1R

3.91e-03186494MM15994
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

CAMK2B CAMK2D CAMK2G

3.99e-0392493MM14951
PathwayWP_ERBB_SIGNALING

CAMK2B CAMK2D CAMK2G

3.99e-0392493M39715
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

VIPR2 CALCRL CRHR2

4.24e-0394493M797
Pubmed

The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons.

TRPC7 TRPM7 TRPC3 TRPC6

1.78e-091061427177420
Pubmed

Identification of novel human tumor cell-specific CaMK-II variants.

CAMK2B CAMK2D CAMK2G

5.13e-0936139060999
Pubmed

Cloning and quantitative determination of the human Ca2+/calmodulin-dependent protein kinase II (CaMK II) isoforms in human beta cells.

CAMK2B CAMK2D CAMK2G

5.13e-09361310819240
Pubmed

Calcium/calmodulin kinase II-dependent acetylcholine receptor cycling at the mammalian neuromuscular junction in vivo.

CAMK2B CAMK2D CAMK2G

5.13e-09361320844140
Pubmed

Major contribution of the 3/6/7 class of TRPC channels to myocardial ischemia/reperfusion and cellular hypoxia/reoxygenation injuries.

TRPC7 TRPC3 TRPC6

5.13e-09361328526717
Pubmed

Melanopsin Phototransduction Is Repurposed by ipRGC Subtypes to Shape the Function of Distinct Visual Circuits.

TRPC7 TRPC3 TRPC6

2.05e-08461330017393
Pubmed

Pulsatile atheroprone shear stress affects the expression of transient receptor potential channels in human endothelial cells.

TRPM7 TRPC3 TRPC6

2.05e-08461322566504
Pubmed

Cadmium activates CaMK-II and initiates CaMK-II-dependent apoptosis in mesangial cells.

CAMK2B CAMK2D CAMK2G

2.05e-08461317367784
Pubmed

Developmental expression of the CaM kinase II isoforms: ubiquitous gamma- and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system.

CAMK2B CAMK2D CAMK2G

2.05e-08461310381553
Pubmed

[Molecular mechanisms of the intracellular localizations of Ca2+/calmodulin-dependent protein kinase II isoforms, and their physiological functions].

CAMK2B CAMK2D CAMK2G

2.05e-08461311889801
Pubmed

Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein.

CAMK2B CAMK2D CAMK2G

5.12e-08561311013247
Pubmed

Transition from reversible to persistent binding of CaMKII to postsynaptic sites and NR2B.

CAMK2B CAMK2D CAMK2G

5.12e-08561316436603
Pubmed

Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure.

CAMK2B CAMK2D CAMK2G

5.12e-08561318218981
Pubmed

TRPC channels are necessary mediators of pathologic cardiac hypertrophy.

TRPC7 TRPC3 TRPC6

5.12e-08561320351294
Pubmed

Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.

CAMK2B CAMK2D CAMK2G

5.12e-08561321209221
Pubmed

Intrinsic phototransduction persists in melanopsin-expressing ganglion cells lacking diacylglycerol-sensitive TRPC subunits.

TRPC7 TRPC3 TRPC6

5.12e-08561321261756
Pubmed

Comparative analyses of the three-dimensional structures and enzymatic properties of alpha, beta, gamma and delta isoforms of Ca2+-calmodulin-dependent protein kinase II.

CAMK2B CAMK2D CAMK2G

5.12e-08561314722083
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPC7 TRPM7 TRPC3 TRPC6

8.86e-082461433884443
Pubmed

Multiple kinases regulate mafA expression in the pancreatic beta cell line MIN6.

CAMK2B CAMK2D CAMK2G

1.02e-07661318948074
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPC7 TRPM7 TRPC3 TRPC6

1.05e-072561416382100
Pubmed

An introduction to TRP channels.

TRPC7 TRPM7 TRPC3 TRPC6

1.46e-072761416460286
Pubmed

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

GPBAR1 VIPR2 MC1R CALCRL CRHR2

1.56e-077061512036966
Pubmed

MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC.

TRPC7 TRPC3 TRPC6

1.79e-07761315757897
Pubmed

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer.

TRPC7 TRPC3 TRPC6

1.79e-07761338835669
Pubmed

Rad and Rad-related GTPases interact with calmodulin and calmodulin-dependent protein kinase II.

CAMK2B CAMK2D CAMK2G

1.79e-0776139115241
Pubmed

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways.

TRPC7 TRPC3 TRPC6

1.79e-07761332350291
Pubmed

TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis.

TRPC7 TRPC3 TRPC6

1.79e-07761336592529
Pubmed

Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models.

TRPC7 TRPC3 TRPC6

1.79e-07761315336983
Pubmed

Subunit composition, molecular environment, and activation of native TRPC channels encoded by their interactomes.

TRPC7 TRPC3 TRPC6

1.79e-07761336257322
Pubmed

Ca(2+)/CaM-dependent kinases: from activation to function.

CAMK2B CAMK2D CAMK2G

2.86e-07861311264466
Pubmed

Subunit composition of mammalian transient receptor potential channels in living cells.

TRPC7 TRPC3 TRPC6

2.86e-07861312032305
Pubmed

Association of immunophilins with mammalian TRPC channels.

TRPC7 TRPC3 TRPC6

2.86e-07861315199065
Pubmed

Structure of the CaMKIIdelta/calmodulin complex reveals the molecular mechanism of CaMKII kinase activation.

CAMK2B CAMK2D CAMK2G

2.86e-07861320668654
Pubmed

Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.

TRPC7 TRPC3 TRPC6

2.86e-07861325471572
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPC7 TRPM7 TRPC3 TRPC6

3.37e-073361419834762
Pubmed

Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels.

TRPC7 TRPC3 TRPC6

4.28e-07961311290752
Pubmed

Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion.

TRPC7 TRPC3 TRPC6

4.28e-07961317480026
Pubmed

Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle.

CAMK2B CAMK2D CAMK2G

4.28e-07961312660151
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPC7 TRPM7 TRPC3 TRPC6

6.04e-073861430786075
Pubmed

CaMKII Signaling Stimulates Mef2c Activity In Vitro but Only Minimally Affects Murine Long Bone Development in vivo.

CAMK2B CAMK2D CAMK2G

6.11e-071061328361052
Pubmed

Heterogeneous distribution of TRPC proteins in the embryonic cortex.

TRPC7 TRPC3 TRPC6

6.11e-071061318989690
Pubmed

The presence and activation of two essential transcription factors (cAMP response element-binding protein and cAMP-dependent transcription factor ATF1) in the two-cell mouse embryo.

CAMK2B CAMK2D CAMK2G

6.11e-071061319776387
Pubmed

Dissociation of heterotrimeric g proteins in cells.

GPBAR1 VIPR2 ADRA1B HTR1F CRHR2 HRH3

7.50e-0717961618577758
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

TRPC7 TRPM7 TRPC3 TRPC6

1.10e-064461419322198
Pubmed

Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma.

CAMK2B CAMK2D CAMK2G

1.12e-06126138615909
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

CAMK2B CAMK2D CAMK2G

1.12e-061261312815021
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

CAMK2B CAMK2D CAMK2G

1.12e-06126138665664
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

VIPR2 ADRA1B HTR1F CALCRL CRHR2 HRH3

1.43e-0620061618240029
Pubmed

Melanopsin signalling in mammalian iris and retina.

TRPC7 TRPC3 TRPC6

1.45e-061361322051675
Pubmed

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

CAMK2B CAMK2D CAMK2G

1.84e-061461310373510
Pubmed

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

CAMK2B CAMK2D CAMK2G

2.30e-061561314622581
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

CAMK2B CAMK2D CAMK2G

2.30e-06156139481670
Pubmed

Tissue distribution, ontogeny, and hormonal regulation of xenobiotic transporters in mouse kidneys.

SLC22A9 SLC22A10 SLC34A3

2.83e-061661319679677
Pubmed

Roles of GPR41 and GPR43 in leptin secretory responses of murine adipocytes to short chain fatty acids.

FFAR3 GPR42

3.03e-06261220399779
Pubmed

Expression of the short chain fatty acid receptor GPR41/FFAR3 in autonomic and somatic sensory ganglia.

FFAR3 GPR42

3.03e-06261225637492
Pubmed

Transient receptor potential channels function as a coincidence signal detector mediating phosphatidylserine exposure.

TRPC3 TRPC6

3.03e-06261223800468
Pubmed

Sequence polymorphisms provide a common consensus sequence for GPR41 and GPR42.

FFAR3 GPR42

3.03e-06261219630535
Pubmed

Selective tracking of FFAR3-expressing neurons supports receptor coupling to N-type calcium channels in mouse sympathetic neurons.

FFAR3 GPR42

3.03e-06261230478340
Pubmed

TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes.

TRPC3 TRPC6

3.03e-06261228105583
Pubmed

3-(4-Hydroxy-3-methoxyphenyl) propionic acid contributes to improved hepatic lipid metabolism via GPR41.

FFAR3 GPR42

3.03e-06261238040866
Pubmed

The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis.

CAMK2B CAMK2G

3.03e-06261215294044
Pubmed

Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.

TRPC3 TRPC6

3.03e-0626129930701
Pubmed

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells.

TRPC3 TRPC6

3.03e-06261222724068
Pubmed

Genetic Inactivation of Free Fatty Acid Receptor 3 Impedes Behavioral Deficits and Pathological Hallmarks in the APPswe Alzheimer's Disease Mouse Model.

FFAR3 GPR42

3.03e-06261235408893
Pubmed

FFAR3 modulates insulin secretion and global gene expression in mouse islets.

FFAR3 GPR42

3.03e-06261226091414
Pubmed

A role for CaMKII in T cell memory.

CAMK2B CAMK2G

3.03e-06261210693762
Pubmed

Structural mechanism of human TRPC3 and TRPC6 channel regulation by their intracellular calcium-binding sites.

TRPC3 TRPC6

3.03e-06261235051376
Pubmed

GPR41 modulates insulin secretion and gene expression in pancreatic β-cells and modifies metabolic homeostasis in fed and fasting states.

FFAR3 GPR42

3.03e-06261227550964
Pubmed

[PI3K/Akt/Erk signaling pathway mediates neuroprotection of CaMKⅡγ and CaMKⅡδ against ischemic reperfusion injury in mice].

CAMK2D CAMK2G

3.03e-06261238597448
Pubmed

Male mice that lack the G-protein-coupled receptor GPR41 have low energy expenditure and increased body fat content.

FFAR3 GPR42

3.03e-06261223110765
Pubmed

Intestinal FFA3 mediates obesogenic effects in mice on a Western diet.

FFAR3 GPR42

3.03e-06261235858247
Pubmed

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation.

FFAR3 GPR42

3.03e-06261226522986
Pubmed

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms.

FFAR3 GPR42

3.03e-06261222506074
Pubmed

Free fatty acid receptor 3 differentially contributes to β-cell compensation under high-fat diet and streptozotocin stress.

FFAR3 GPR42

3.03e-06261232073900
Pubmed

CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation.

CAMK2D CAMK2G

3.03e-06261231619570
Pubmed

Diacylglycerol-containing oleic acid induces increases in [Ca(2+)](i) via TRPC3/6 channels in human T-cells.

TRPC3 TRPC6

3.03e-06261222306362
Pubmed

Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41.

FFAR3 GPR42

3.03e-06261214722361
Pubmed

[Regulation of cardiac hypertrophy by the formation of G protein-coupled receptor--TRPC channel protein complex].

TRPC3 TRPC6

3.03e-06261219749484
Pubmed

Microbial short chain fatty acid metabolites lower blood pressure via endothelial G protein-coupled receptor 41.

FFAR3 GPR42

3.03e-06261227664183
Pubmed

Ischemic Injury-Induced CaMKIIδ and CaMKIIγ Confer Neuroprotection Through the NF-κB Signaling Pathway.

CAMK2D CAMK2G

3.03e-06261229992531
Pubmed

Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy.

TRPC3 TRPC6

3.03e-06261224453217
Pubmed

CaMK-II oligomerization potential determined using CFP/YFP FRET.

CAMK2B CAMK2D

3.03e-06261216185778
Pubmed

Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein.

TRPC3 TRPC6

3.03e-0626129368034
Pubmed

Ca2+/calmodulin-dependent protein kinase II-γ (CaMKIIγ) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling.

CAMK2D CAMK2G

3.03e-06261226567004
Pubmed

The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41.

FFAR3 GPR42

3.03e-06261224748202
Pubmed

Modulation of Transient Receptor Potential Channels 3 and 6 Regulates Osteoclast Function with Impact on Trabecular Bone Loss.

TRPC3 TRPC6

3.03e-06261232140760
Pubmed

[Mechanism of cardiac hypertrophy via diacylglycerol-sensitive TRPC channels].

TRPC3 TRPC6

3.03e-06261220190513
Pubmed

Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance.

CAMK2D CAMK2G

3.03e-06261234303021
Pubmed

Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II.

TRPC7 TRPC6

3.03e-06261223529130
Pubmed

The Cognitive Improvement and Alleviation of Brain Hypermetabolism Caused by FFAR3 Ablation in Tg2576 Mice Is Persistent under Diet-Induced Obesity.

FFAR3 GPR42

3.03e-06261236362376
Pubmed

DHA induces Jurkat T-cell arrest in G2/M phase of cell cycle and modulates the plasma membrane expression of TRPC3/6 channels.

TRPC3 TRPC6

3.03e-06261233333171
Pubmed

Cardiac CaM Kinase II genes δ and γ contribute to adverse remodeling but redundantly inhibit calcineurin-induced myocardial hypertrophy.

CAMK2D CAMK2G

3.03e-06261225124496
Pubmed

Upregulation and Diverse Roles of TRPC3 and TRPC6 in Synaptic Reorganization of the Mossy Fiber Pathway in Temporal Lobe Epilepsy.

TRPC3 TRPC6

3.03e-06261225213992
Pubmed

Human GPR42 is a transcribed multisite variant that exhibits copy number polymorphism and is functional when heterologously expressed.

FFAR3 GPR42

3.03e-06261226260360
Pubmed

G protein coupled receptor 41 regulates fibroblast activation in pulmonary fibrosis via Gαi/o and downstream Smad2/3 and ERK1/2 phosphorylation.

FFAR3 GPR42

3.03e-06261237019194
Pubmed

Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension.

TRPC3 TRPC6

3.03e-06261227861908
Pubmed

A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia.

TRPC3 TRPC6

3.03e-06261235805125
Pubmed

N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity.

TRPC3 TRPC6

3.03e-06261212970363
Pubmed

Structure of the receptor-activated human TRPC6 and TRPC3 ion channels.

TRPC3 TRPC6

3.03e-06261229700422
Pubmed

CaM Kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury.

CAMK2D CAMK2G

3.03e-06261225193973
InteractionTRPC7 interactions

TRPC7 TRPC3 TRPC6

3.82e-076553int:TRPC7
InteractionCIBAR2 interactions

CAMK2B CAMK2D CAMK2G

6.68e-077553int:CIBAR2
InteractionCAMK2N1 interactions

CAMK2B CAMK2D CAMK2G

2.28e-0610553int:CAMK2N1
InteractionFAM163B interactions

CAMK2B CAMK2D CAMK2G

1.52e-0518553int:FAM163B
InteractionLTC4S interactions

FFAR3 GPR42 CAMK2G

2.12e-0520553int:LTC4S
InteractionITPR3 interactions

TRPC7 CAMK2B CAMK2D CAMK2G TRPC3 TRPC6

2.32e-05211556int:ITPR3
InteractionSERINC1 interactions

SLC22A9 VIPR2 FFAR3 GPR42

2.62e-0563554int:SERINC1
InteractionAGPAT5 interactions

GPBAR1 CAMK2B CAMK2D CAMK2G

4.45e-0572554int:AGPAT5
InteractionMAP10 interactions

CAMK2B CAMK2D CAMK2G

6.68e-0529553int:MAP10
InteractionPDE4A interactions

CAMK2B CAMK2D CAMK2G

7.41e-0530553int:PDE4A
InteractionTRPC3 interactions

TRPC7 TRPC3 TRPC6

9.90e-0533553int:TRPC3
InteractionTMEM60 interactions

GPR42 TMEM86B KCNK5 SLC23A2

1.16e-0492554int:TMEM60
InteractionCAMK2N2 interactions

CAMK2B CAMK2G

1.52e-047552int:CAMK2N2
InteractionDNAL4 interactions

CAMK2B CAMK2D CAMK2G

1.64e-0439553int:DNAL4
InteractionPLCB3 interactions

TRPM7 CAMK2B CAMK2G TRPC3

1.67e-04101554int:PLCB3
InteractionSLC41A1 interactions

FFAR3 GPR42 SLC23A2

1.77e-0440553int:SLC41A1
InteractionSHISA6 interactions

CAMK2B CAMK2D CAMK2G

2.20e-0443553int:SHISA6
InteractionSH2D1A interactions

CAMK2B CAMK2D CAMK2G

2.52e-0445553int:SH2D1A
Cytoband14q11.2

OR4K17 OR11H4 OR4K5 SLC22A17 OR4L1 OR11H6

1.55e-0718061614q11.2
CytobandEnsembl 112 genes in cytogenetic band chr14q11

OR4K17 OR11H4 OR4K5 SLC22A17 OR4L1 OR11H6

5.43e-06332616chr14q11
Cytoband19p13.11

MPV17L2 ATP13A1 NIBAN3

1.30e-047361319p13.11
Cytoband19q13.1

FFAR3 GPR42

2.46e-035561219q13.1
GeneFamilyTransient receptor potential cation channels

TRPC7 TRPM7 TRPC3 TRPC6

7.18e-0728464249
GeneFamilySolute carriers

SLC22A9 SLC22A10 SLC49A4 SLC34A3 SLC30A1 SLC23A2 SLC22A17 SLC16A10

6.10e-06395468752
GeneFamilyG protein-coupled receptors, Class A orphans

GPR42 MRGPRE GPR85

1.03e-0378463262
GeneFamilyOlfactory receptors, family 11

OR11H4 OR11H6

1.55e-0323462159
GeneFamilyOlfactory receptors, family 4

OR4K17 OR4K5 OR4L1

4.31e-03129463151
ToppCellfrontal_cortex|World / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADRA1B TRPC7 HTR1F TRPC3 HRH3

1.94e-06152605f9c29d4568402ca07a717dbffb3ccc7f35c5fe56
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

VIPR2 EPHA6 CAMK2D TRPC3 CRHR2

3.75e-06174605ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 VIPR2 HTR1F TRPC3 SLC22A10

3.97e-06176605cd4b9211652596c42e7af318bcd464681daebb10
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 HTR1F CAMK2D SLC22A10 TM6SF1

4.43e-06180605b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 HTR1F CAMK2D SLC22A10 TM6SF1

4.43e-06180605f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1B KCNU1 TRPC3 TRPC6 CRHR2

4.93e-0618460555dde9c4eebac2a33788c1ff1d8fe312d150fad4
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1B KCNU1 TRPC3 TRPC6 CRHR2

4.93e-061846057128a2be291544d3df3ed6c80f21ddda8437dcba
ToppCelldroplet-Lung-30m-Mesenchymal-myofibroblast-pericyte_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1B KCNU1 TRPC3 TRPC6 CRHR2

4.93e-06184605d14238f7b0b55a4c8d7040bea854bd221a66ac30
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

CYSLTR2 FFAR3 GPR42 SLC49A4 PELI1

6.22e-061936053479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

CYSLTR2 FFAR3 GPR42 SLC49A4 PELI1

6.54e-06195605fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellT_cells-CCR7+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

SPART PELI1 SLC22A17 GSPT1 SLC16A10

7.22e-06199605467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNU1 KCNK5 TMC5 ABCA9

4.16e-051436044a0f26eef935fe68a1da5d319503059a8a8682dd
ToppCellLPS-antiTNF-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCNU1 KCNK5 TMC5 ABCA9

4.16e-0514360465328a0a2f3972fac596e07933e74b2ef7cceb84
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNU1 NIBAN3 CRHR2 HRH3

6.75e-0516260422f1abd20f43bc7e7fc46969da9962faf70ae5d2
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNU1 NIBAN3 CRHR2 HRH3

6.75e-05162604966df4558140c3d541999ab553f201ae76a1c401
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CYSLTR2 CAMK2B GPR85 CRHR2

7.25e-051656049795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

ASPHD1 NYNRIN LHFPL2 SLC16A10

7.77e-051686048ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_4|390C / Donor, Lineage, Cell class and subclass (all cells)

CYSLTR2 NYNRIN LHFPL2 SLC16A10

8.13e-05170604439167e44a1bd5ac8e1e457351dd202ec968db46
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYSLTR2 HTR1F TRPC6 ABCA9

8.32e-05171604a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-mature_NK_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D10C CYSLTR2 ATP8A2 TRPC6

8.32e-05171604d322cc042a6f4b4aa8ef80ae977edbce9e266d48
ToppCellImmune_cells-pro-B|World / Lineage and Cell class

TBC1D10C CAMK2B CAMK2D NIBAN3

8.90e-05174604e173adbf5789dfa20f3cbc668efde5f0992ac219
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 VIPR2 HTR1F SLC22A10

9.72e-051786045522b179c2e7dd707de01e2df10556349d0382a6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 VIPR2 HTR1F SLC22A10

9.72e-05178604731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_HNRNPA1P46|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 EPHA6 CAMK2D CRHR2

9.93e-05179604c815eb9f760fe4ca7a5e49beb224659f0b864f22
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIPR2 TRPC3 SLC22A17 SLC16A10

9.93e-05179604e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNU1 TRPC3 TRPC6 CRHR2

9.93e-05179604bfc226bcf0b93525992344f968268a261d86fcbf
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNU1 TRPC3 TRPC6 CRHR2

9.93e-0517960436ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 VIPR2 HTR1F SLC22A10

1.01e-041806042ae39e26a8e7d5d4d3e1e71609a8ec36fd9855aa
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC22A9 VIPR2 HTR1F SLC22A10

1.04e-041816046e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPBAR1 ASPHD1 CAMK2B GPR85

1.08e-04183604d26c7b79895de28961b8d68351f28d4bb531c75c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

HIPK3 HTR1F TM6SF1 ABCA9

1.10e-0418460467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CYSLTR2 LHFPL2 CALCRL TM6SF1

1.15e-0418660492092f11ecce22c14f244e42c499af0822977e6f
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYSLTR2 TRPC3 TRPC6 CRHR2

1.20e-04188604a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCellCOPD-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

CYSLTR2 FFAR3 GPR42 PELI1

1.25e-04190604aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ASPHD1 EPHA6 CAMK2B HRH3

1.25e-04190604416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellControl-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

VIPR2 SPART CALCRL NIBAN3

1.35e-041946045f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

CYSLTR2 KCNU1 SLC49A4 SLC16A10

1.35e-04194604800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellControl-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

FFAR3 GPR42 SLC49A4 PELI1

1.38e-04195604b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCellCaecum-T_cell-Tfh|T_cell / Region, Cell class and subclass

CAMK2D CALCRL ABCA9 SLC22A17

1.41e-04196604fe2ee5788028e6b671674f0cc50e2b6379f50976
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CYSLTR2 HTR1F TRPC3 ABCA9

1.41e-0419660412d9028f90c057c6e5cff00301793fa550e86c5a
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic-Mesothelia|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VIPR2 ADRA1B ASPHD1 SLC30A1

1.44e-0419760426888af95a7cc082a1f1218af35b1f07cb9436ed
ToppCellBronchial-10x5prime-Stromal-Mesofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

VIPR2 ADRA1B ASPHD1 SLC30A1

1.44e-04197604438de7f0d35d81d5f5e41dcef7b2c54b6da03df4
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HTR1F MPV17L2 TRPC3 TRPC6

1.46e-04198604882710bd6215e299257dd3df234292db9a2823ba
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CYSLTR2 PELI1 SLC30A1 SLC16A10

1.49e-04199604951c2ea5af4756832c2adcec3ee70a7e36331a4e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADRA1B TRPC7 CAMK2B ATP8A2

1.52e-042006042f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TBC1D10C ATP13A1 MC1R SLC16A10

1.52e-0420060488d713dfc792e7609bf7ecfb28f87cb748088570
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADRA1B TRPC7 CAMK2B ATP8A2

1.52e-04200604bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

EPHA6 GPR85 CYB561D1 SLC23A2

1.52e-04200604a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ADRA1B TRPC7 CAMK2B ATP8A2

1.52e-04200604dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

ASPHD1 CAMK2B ATP8A2 GPR85

1.52e-042006046f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Non-Seminoma-_Embryonal_Carcinoma,_Immature_Teratoma,_Yolk_Sac_Tumor|TCGA-Testes / Sample_Type by Project: Shred V9

VIPR2 OR4K5 CRHR2

1.60e-047860335e6b026a7fbef495d0fc620677d3f1495b743fc
DrugCalcium

GPBAR1 CYSLTR2 ADRA1B TRPC7 KISS1R TRPM7 CAMK2D TRPC3 TRPC6 SLC30A1 SLC23A2 HRH3

6.19e-094936112ctd:D002118
Drug2-aminoethyl diphenylborinate

TRPC7 KISS1R TRPM7 CAMK2B CAMK2D TRPC3 TRPC6

4.83e-08127617CID000001598
Drug1-oleoyl-2-acetylglycerol

TRPC7 TRPC3 TRPC6

8.14e-0615613ctd:C038237
DrugAstemizole [68844-77-9]; Down 200; 8.8uM; MCF7; HT_HG-U133A

CAMK2B CAMK2G TM6SF1 SLC23A2 SLC22A17 SLC16A10

1.18e-051906166807_DN
DrugGW 7845

CAMK2B CAMK2D CAMK2G

1.45e-0518613ctd:C401311
DrugAlthiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A

HIPK3 VIPR2 CAMK2G TMC5 SLC22A17 PIGO

1.50e-051986166089_DN
DrugBetahistine mesylate [54856-23-4]; Up 200; 17.2uM; PC3; HT_HG-U133A

HIPK3 CAMK2B NYNRIN GPR85 SPART PIGO

1.50e-051986166611_UP
DrugTroleandomycin [2751-09-9]; Up 200; 5uM; PC3; HT_HG-U133A

HIPK3 VIPR2 CYSLTR2 ATP8A2 CRHR2 GSPT1

1.54e-051996163985_UP
DrugA0666_sigma

ADRA1B CAMK2B CAMK2D CALCRL

1.54e-0556614CID000005680
DrugD-myo-inositol-1,4,5-triphosphate

VIPR2 ADRA1B TRPC7 CAMK2B FFAR3 CAMK2D TRPC3 TRPC6 HRH3

1.92e-05568619CID000000806
Drugadenosine 3',5'-cyclic phosphate

VIPR2 ADRA1B HTR1F CAMK2B ATP8A2 CAMK2D CAMK2G MC1R CALCRL CRHR2 HRH3

2.54e-059076111CID000000274
DrugSB204741

HTR1F CAMK2B CAMK2D

3.56e-0524613CID003277600
DrugHF-2035

CAMK2B CAMK2D CAMK2G

4.04e-0525613CID006439511
DrugSB 206553

HTR1F CAMK2B CAMK2D

4.55e-0526613CID000005163
Drugforskolin from Coleus forskohlii

VIPR2 ADRA1B HTR1F CAMK2B FFAR3 CAMK2D MC1R KCNK5 CALCRL CRHR2 HRH3

6.94e-0510136111CID000003413
DrugBEA 1654

ADRA1B HTR1F

7.02e-055612CID000125354
Drugcarbachol

VIPR2 ADRA1B TRPC7 TRPM7 CAMK2B CAMK2D TRPC3 TRPC6 HRH3

8.49e-05688619CID000002551
Drugcimetidine

SLC22A9 ATP8A2 CALCRL SLC23A2 HRH3

1.18e-04179615CID000002756
DrugK-II

TRPM7 CAMK2B CAMK2D CAMK2G

1.29e-0496614CID000129400
Drugborate

GPBAR1 TRPM7 TRPC3 TRPC6

1.40e-0498614CID000007628
Drugaminocyclohexanecarboxylic acid

CAMK2B CAMK2D

1.47e-047612CID000171560
DrugTAS-301

CAMK2B CAMK2D

1.47e-047612CID009885087
DrugAC1L1H4K

ADRA1B HTR1F HRH3

1.56e-0439613CID000003972
DrugCarbenoxolone disodium salt [7421-40-1]; Down 200; 6.6uM; MCF7; HT_HG-U133A

HIPK3 VIPR2 HTR1F SLC22A17 GSPT1

1.68e-041936154173_DN
DrugTocopherol (R,S) [10191-41-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

CAMK2B SLC23A2 SLC22A17 CRHR2 HRH3

1.72e-041946154961_UP
DrugDienestrol [84-17-3]; Up 200; 15uM; MCF7; HT_HG-U133A

VIPR2 HTR1F ASPHD1 PELI1 SLC30A1

1.72e-041946156208_UP
DrugSuxibuzone [27470-51-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

VIPR2 HTR1F ATP8A2 SPART SLC23A2

1.77e-041956156065_UP
Drugmetoprolol

GPBAR1 ADRA1B HTR1F HRH3

1.82e-04105614CID000004171
Drugbeta- Belladonnine dichloroethylate [191355-47-2]; Up 200; 6uM; PC3; HT_HG-U133A

CAMK2B TM6SF1 CRHR2 HRH3 GSPT1

1.85e-041976156638_UP
DrugAlfadolone acetate [23930-37-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A

ASPHD1 CAMK2G TRPC3 GPR85 PIGO

1.85e-041976156506_UP
Drugbosentan

TRPC7 TRPM7 TRPC3 TRPC6

1.89e-04106614CID000104865
DrugAC1L9NAZ

VIPR2 TRPM7 MC1R CALCRL HRH3

1.90e-04198615CID000449606
DrugEthisterone [434-03-7]; Up 200; 12.8uM; MCF7; HT_HG-U133A

HTR1F CAMK2B NYNRIN KCNK5 SLC22A17

1.90e-041986153864_UP
DrugFlucytosine [2022-85-7]; Up 200; 31uM; MCF7; HT_HG-U133A

HTR1F CAMK2G TM6SF1 SLC23A2 SLC16A10

1.90e-041986155289_UP
DrugCefoperazone dihydrate; Up 200; 5.8uM; MCF7; HT_HG-U133A

HIPK3 KCNK5 TMC5 CRHR2 GSPT1

1.90e-041986155424_UP
DrugFuraltadone hydrochloride [3759-92-0]; Up 200; 11uM; HL60; HT_HG-U133A

HIPK3 SPART LHFPL2 CRHR2 GSPT1

1.90e-041986152554_UP
DrugDiethylstilbestrol [56-53-1]; Down 200; 15uM; MCF7; HT_HG-U133A

VIPR2 CAMK2B CAMK2G SLC22A17 PIGO

1.90e-041986153895_DN
DrugNapelline [5008-52-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

HTR1F CAMK2B ATP8A2 NYNRIN KCNK5

1.90e-041986154486_UP
DrugHomosalate [118-56-9]; Down 200; 15.2uM; MCF7; HT_HG-U133A

VIPR2 KCNK5 SLC23A2 SLC22A17 GSPT1

1.94e-041996153879_DN
Drugpranlukast

SLC22A9 CYSLTR2

1.96e-048612ctd:C047681
Drugcalcium peroxide

HIPK3 GPBAR1

1.96e-048612CID000014779
Drug1-oleoyl-2-acetoyl-sn-glycerol

TRPC3 TRPC6

1.96e-048612ctd:C520323
DrugDimebon

ADRA1B HRH3

1.96e-048612CID000197033
Drugflufenamic acid

TRPC7 KISS1R TRPC3 TRPC6

2.03e-04108614CID000003371
DrugSC-9

ADRA1B CAMK2B CAMK2D

2.09e-0443613CID000124172
DrugBAPTA

KISS1R TRPM7 CAMK2B CAMK2D TRPC3 TRPC6

2.28e-04324616CID000104751
Diseaseheart conduction disease (implicated_via_orthology)

KCNU1 CAMK2B CAMK2D CAMK2G KCNK5

4.35e-0932575DOID:10273 (implicated_via_orthology)
Diseasenicotine dependence (implicated_via_orthology)

TRPC7 TRPC3 TRPC6

1.49e-0612573DOID:0050742 (implicated_via_orthology)
Diseaseestrogen measurement

SLC22A9 SLC22A10

1.63e-0410572EFO_0011007
Diseaseperipheral neuropathy, response to docetaxel trihydrate

TRPC7 ATP8A2

6.14e-0419572EFO_0003100, GO_1902519
Diseasebowel opening frequency

FFAR3 GPR42

1.54e-0330572EFO_0600084
Diseaseeating disorder

ATP8A2 KCNK5

1.75e-0332572EFO_0005203
Diseaseright ventricular systolic volume measurement

CAMK2D SLC23A2

2.09e-0335572EFO_0021815
Diseaserhinitis (is_marker_for)

CYSLTR2 CRHR2

3.59e-0346572DOID:4483 (is_marker_for)
Diseasetryptophan measurement

TRPC3 SLC16A10

4.07e-0349572EFO_0008534
Diseasemean reticulocyte volume

HTR1F NYNRIN TRPC3 TMEM86B PIGO SLC16A10

4.34e-03799576EFO_0010701
DiseaseHypertensive disease

TRPC3 CRHR2 HRH3

5.96e-03190573C0020538

Protein segments in the cluster

PeptideGeneStartEntry
GAAWYLCLALPVYPA

CYB561D1

196

Q8N8Q1
GLILGAFVICWLPFF

HTR1F

296

P30939
FWGILGFPALYTRLP

ABCA9

341

Q8IUA7
TVLPFAGLLYPAWLG

ATP13A1

66

Q9HD20
CWLPFFIALPLGSLF

ADRA1B

306

P35368
APLCGFPWYLPVHFL

ERMP1

741

Q7Z2K6
WCIGLYNVIFTALPP

ATP8A2

911

Q9NTI2
FPFPLGWLGGYLAVL

SLC34A3

366

Q8N130
LLGIFFLCWGPFFLH

MC1R

246

Q01726
FIRGWGLCIFLPFVL

NIBAN3

526

Q86XR2
SFCWLIGFLGYPIPI

OR11H4

156

Q8NGC9
CWVGGFLCYPVPIVL

OR11H6

166

Q8NGC7
PLLGVWYFLGLGCLE

MPV17L2

111

Q567V2
LLFGLCWGPYVATLL

GPBAR1

231

Q8TDU6
WSPPLAPGCYQLLLY

ASPHD1

241

Q5U4P2
LLPFQLWCPRPFGTY

FBXO46

6

Q6PJ61
VFYGLFGVPLCLTWI

KCNK5

116

O95279
FGPCIFIYVWPFTIS

OR4K5

251

Q8NGD3
ILFFGPCIFIYIWPF

OR4K17

251

Q8NGC6
FGPCIFIYVWPFSSL

OR4L1

251

Q8NH43
LFLFIGWCIPFPIIV

CRHR2

226

Q13324
LLYPLPGWVLGDFMC

KISS1R

101

Q969F8
FLILGLILYPAGWGC

LHFPL2

146

Q6ZUX7
FLWNFPQIYILPGCA

KCNU1

766

A8MYU2
ACWLVGFLTPILPIY

OR6Q1

151

Q8NGQ2
FLFCGLPFGIYWLSR

MRGPRE

226

Q86SM8
WPLPFILCPLSGFIF

GPR42

81

O15529
GCVIAELFLGWPLYP

HIPK3

386

Q9H422
CPWYIGLPFIPYLDN

GSPT1

276

P15170
ALLVLWGPIGFLPCF

SLC49A4

91

Q96SL1
WPLPFILCPLSGFIF

FFAR3

81

O14843
FCIPLYVPYVLTGRW

HRH3

86

Q9Y5N1
TFLFLTLWGPYLVAC

GPR85

291

P60893
YFLGWGFPLIPACIH

CALCRL

256

Q16602
GVILYILLVGYPPFW

CAMK2G

201

Q13555
GVILYILLVGYPPFW

CAMK2D

201

Q13557
YRIWGFPTPEKLGCI

NYNRIN

1861

Q9P2P1
PYVPLWLGCEAGFYV

PELI1

341

Q96FA3
LQFGFFLPLLTAWPG

EPHA6

11

Q9UF33
ICWGLGIEYTFPPLY

MRPS15

181

P82914
GVILYILLVGYPPFW

CAMK2B

201

Q13554
TAPCILFLFYGWPGL

SLC22A17

221

Q8WUG5
PLPWIIYGVFPFISG

SLC22A9

496

Q8IVM8
LPWIIYGIFPIIGGL

SLC22A10

496

Q63ZE4
FPIVYLIIFFWGVLG

CYSLTR2

41

Q9NS75
PGFLQVCDWLYPLVP

SPART

266

Q8N0X7
VPPWYLCIFLGLQHY

SLC23A2

96

Q9UGH3
VGPLLYLPEWFLCLF

TBC1D10C

246

Q8IV04
YVWAFGFSPLQPGLL

TMEM86B

111

Q8N661
YQLGEFILLFNPWCP

TGM5

131

O43548
IYIIVSPLCGGFTWP

VAMP7

201

P51809
PPRRCFLAYLLIGWG

VIPR2

236

P41587
GFPFCPLLLTPVAWG

PIGO

476

Q8TEQ8
LVWIGIFFCPLLPFI

TMC5

786

Q6UXY8
GLPFLALIYWFAPCS

TRPC6

416

Q9Y210
YEAGPCWVLYLDPTL

SLC30A1

306

Q9Y6M5
CGPGTWLTPFLQAVY

TRPM7

1066

Q96QT4
LGLPFLAIGYWIAPC

TRPC3

346

Q13507
FFLSIPYTCLPVWAG

TM6SF1

171

Q9BZW5
GLPFLAIAYWIAPCS

TRPC7

361

Q9HCX4
WAVGIPLALFGYFVP

SLC16A10

296

Q8TF71