Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN2A SCN5A SCN7A	8.11e-05	26	65	3	GO:0005248
GeneOntologyMolecularFunction	transmembrane transporter binding	AKAP6 KCNB1 SCN5A SCN7A PKP2	2.43e-04	172	65	5	GO:0044325
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	AKAP6 MYH7B SCN2A SCN5A SCN7A PKP2	5.22e-07	93	66	6	GO:0086003
GeneOntologyBiologicalProcess	actin-mediated cell contraction	AKAP6 MYH7B SCN2A SCN5A SCN7A PKP2	3.25e-06	127	66	6	GO:0070252
GeneOntologyBiologicalProcess	actin filament-based movement	AKAP6 MYH7B SCN2A SCN5A SCN7A PKP2	9.50e-06	153	66	6	GO:0030048
GeneOntologyBiologicalProcess	regulation of cardiac muscle cell contraction	AKAP6 MYH7B SCN5A PKP2	1.07e-05	43	66	4	GO:0086004
GeneOntologyBiologicalProcess	cardiac muscle contraction	AKAP6 MYH7B SCN2A SCN5A SCN7A PKP2	1.57e-05	167	66	6	GO:0060048
GeneOntologyBiologicalProcess	regulation of actin filament-based movement	AKAP6 MYH7B SCN5A PKP2	2.49e-05	53	66	4	GO:1903115
GeneOntologyBiologicalProcess	action potential	AKAP6 KCNB1 SCN2A SCN5A SCN7A PKP2	4.44e-05	201	66	6	GO:0001508
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	SCN2A SCN5A SCN7A PKP2	4.64e-05	62	66	4	GO:0086002
GeneOntologyBiologicalProcess	striated muscle contraction	AKAP6 MYH7B SCN2A SCN5A SCN7A PKP2	6.79e-05	217	66	6	GO:0006941
GeneOntologyBiologicalProcess	cardiac muscle tissue development	AKAP6 ERBB4 BMPR2 UBE4B SCN5A PKP2 FGFR1	8.25e-05	327	66	7	GO:0048738
GeneOntologyBiologicalProcess	positive regulation of organ growth	AKAP6 ERBB4 SASH3 FGFR1	8.82e-05	73	66	4	GO:0046622
GeneOntologyBiologicalProcess	protein retention in Golgi apparatus	VPS13C VPS13A	1.00e-04	5	66	2	GO:0045053
GeneOntologyBiologicalProcess	maintenance of protein location in cell	SP100 VPS13C VPS13A PKP2	1.03e-04	76	66	4	GO:0032507
GeneOntologyBiologicalProcess	chromosome segregation	HAUS8 SYCP2 CEP85 STAG1 CDC16 TEX15 SPAG5 KNL1	1.15e-04	465	66	8	GO:0007059
GeneOntologyBiologicalProcess	striated muscle tissue development	AKAP6 ERBB4 BMPR2 UBE4B SCN5A PKP2 FGFR1	1.24e-04	349	66	7	GO:0014706
GeneOntologyBiologicalProcess	mitotic cell cycle phase	SYCP2 NFE2L1	1.50e-04	6	66	2	GO:0098763
GeneOntologyBiologicalProcess	cell cycle process	HAUS8 TAOK3 SYCP2 CEP85 STAG1 NFE2L1 CDC16 PDE4DIP FGFR1 TAF2 TEX15 BIRC6 SPAG5 KNL1	1.54e-04	1441	66	14	GO:0022402
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	SCN2A SCN5A SCN7A PKP2	1.74e-04	87	66	4	GO:0086001
GeneOntologyBiologicalProcess	protein targeting	AKAP6 PIKFYVE KCNB1 VPS13C VPS13A SRP54 HUWE1	1.86e-04	373	66	7	GO:0006605
GeneOntologyBiologicalProcess	regulation of cardiac muscle contraction	AKAP6 MYH7B SCN5A PKP2	1.90e-04	89	66	4	GO:0055117
GeneOntologyBiologicalProcess	blood circulation	AKAP6 DOCK5 BMPR2 MYH7B SCN2A SCN5A SCN7A PKP2 BCR	2.11e-04	648	66	9	GO:0008015
GeneOntologyBiologicalProcess	nuclear division	SYCP2 CEP85 STAG1 NFE2L1 CDC16 TEX15 SPAG5 KNL1	2.22e-04	512	66	8	GO:0000280
GeneOntologyBiologicalProcess	muscle contraction	AKAP6 DOCK5 MYH7B SCN2A SCN5A SCN7A PKP2	2.85e-04	400	66	7	GO:0006936
GeneOntologyBiologicalProcess	heart contraction	AKAP6 MYH7B SCN2A SCN5A SCN7A PKP2	3.80e-04	298	66	6	GO:0060047
GeneOntologyBiologicalProcess	regulation of striated muscle contraction	AKAP6 MYH7B SCN5A PKP2	4.43e-04	111	66	4	GO:0006942
GeneOntologyBiologicalProcess	maintenance of protein location	SP100 VPS13C VPS13A PKP2	4.58e-04	112	66	4	GO:0045185
GeneOntologyBiologicalProcess	organelle fission	SYCP2 CEP85 STAG1 NFE2L1 CDC16 TEX15 SPAG5 KNL1	4.60e-04	571	66	8	GO:0048285
GeneOntologyBiologicalProcess	heart process	AKAP6 MYH7B SCN2A SCN5A SCN7A PKP2	4.60e-04	309	66	6	GO:0003015
GeneOntologyBiologicalProcess	regulation of muscle contraction	AKAP6 DOCK5 MYH7B SCN5A PKP2	4.72e-04	202	66	5	GO:0006937
GeneOntologyBiologicalProcess	mitotic nuclear division	CEP85 STAG1 NFE2L1 CDC16 SPAG5 KNL1	5.18e-04	316	66	6	GO:0140014
GeneOntologyBiologicalProcess	circulatory system process	AKAP6 DOCK5 BMPR2 MYH7B SCN2A SCN5A SCN7A PKP2 BCR	5.20e-04	733	66	9	GO:0003013
GeneOntologyBiologicalProcess	regulation of blood circulation	AKAP6 DOCK5 BMPR2 MYH7B SCN5A PKP2	6.10e-04	326	66	6	GO:1903522
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN2A SCN5A SCN7A	1.98e-05	17	66	3	GO:0001518
GeneOntologyCellularComponent	intercalated disc	AKAP6 SCN2A SCN5A PKP2	6.34e-05	68	66	4	GO:0014704
GeneOntologyCellularComponent	sodium channel complex	SCN2A SCN5A SCN7A	1.04e-04	29	66	3	GO:0034706
GeneOntologyCellularComponent	cell-cell contact zone	AKAP6 SCN2A SCN5A PKP2	2.23e-04	94	66	4	GO:0044291
GeneOntologyCellularComponent	sarcolemma	AKAP6 KCNB1 SCN2A SCN5A DTNBP1	3.36e-04	190	66	5	GO:0042383
GeneOntologyCellularComponent	caveola	AKAP6 ERBB4 BMPR2 SCN5A	4.21e-04	111	66	4	GO:0005901
GeneOntologyCellularComponent	spindle pole	HAUS8 CEP85 STAG1 BIRC6 SPAG5	4.75e-04	205	66	5	GO:0000922
GeneOntologyCellularComponent	cation channel complex	AKAP6 KCNB1 SCN2A SCN5A SCN7A	8.80e-04	235	66	5	GO:0034703
GeneOntologyCellularComponent	membrane raft	AKAP6 PIKFYVE ERBB4 BMPR2 SCN5A TLR6	9.80e-04	362	66	6	GO:0045121
GeneOntologyCellularComponent	membrane microdomain	AKAP6 PIKFYVE ERBB4 BMPR2 SCN5A TLR6	1.01e-03	364	66	6	GO:0098857
GeneOntologyCellularComponent	plasma membrane raft	AKAP6 ERBB4 BMPR2 SCN5A	1.21e-03	147	66	4	GO:0044853
GeneOntologyCellularComponent	T-tubule	AKAP6 SCN2A SCN5A	2.00e-03	79	66	3	GO:0030315
Domain	ARM-type_fold	DOCK5 STAG1 XPO5 UBR4 USP24 MROH5 PKP2 TAF2 UNC45A HUWE1 PPP4R4	2.24e-08	339	65	11	IPR016024
Domain	Na_channel_asu	SCN2A SCN5A SCN7A	4.74e-06	10	65	3	IPR001696
Domain	Na_trans_assoc	SCN2A SCN5A SCN7A	4.74e-06	10	65	3	IPR010526
Domain	Na_trans_assoc	SCN2A SCN5A SCN7A	4.74e-06	10	65	3	PF06512
Domain	VPS13	VPS13C VPS13A	3.57e-05	3	65	2	IPR026847
Domain	VPS13_mid_rpt	VPS13C VPS13A	3.57e-05	3	65	2	PF16910
Domain	VPS13	VPS13C VPS13A	3.57e-05	3	65	2	PF16908
Domain	VPS13_N2	VPS13C VPS13A	3.57e-05	3	65	2	IPR031646
Domain	VPS13_mid_rpt	VPS13C VPS13A	3.57e-05	3	65	2	IPR031642
Domain	ARM-like	STAG1 XPO5 MROH5 PKP2 UNC45A HUWE1 PPP4R4	4.16e-05	270	65	7	IPR011989
Domain	Channel_four-helix_dom	KCNB1 SCN2A SCN5A SCN7A	4.59e-05	57	65	4	IPR027359
Domain	-	KCNB1 SCN2A SCN5A SCN7A	4.59e-05	57	65	4	1.20.120.350
Domain	VPS13_C	VPS13C VPS13A	7.12e-05	4	65	2	PF16909
Domain	SHR-BD	VPS13C VPS13A	7.12e-05	4	65	2	IPR009543
Domain	VPS13_C	VPS13C VPS13A	7.12e-05	4	65	2	IPR031645
Domain	SHR-BD	VPS13C VPS13A	7.12e-05	4	65	2	PF06650
Domain	ATG_C	VPS13C VPS13A	1.18e-04	5	65	2	PF09333
Domain	Autophagy-rel_C	VPS13C VPS13A	1.18e-04	5	65	2	IPR015412
Domain	Na_trans_cytopl	SCN2A SCN5A	1.77e-04	6	65	2	PF11933
Domain	Na_trans_cytopl	SCN2A SCN5A	1.77e-04	6	65	2	IPR024583
Domain	IQ	MYH7B SCN2A SCN5A SCN7A	1.82e-04	81	65	4	SM00015
Domain	IQ_motif_EF-hand-BS	MYH7B SCN2A SCN5A SCN7A	2.73e-04	90	65	4	IPR000048
Domain	IQ	MYH7B SCN2A SCN5A MYH15	3.09e-04	93	65	4	PS50096
Domain	VPS13_N	VPS13C VPS13A	3.29e-04	8	65	2	IPR026854
Domain	Chorein_N	VPS13C VPS13A	3.29e-04	8	65	2	PF12624
Domain	Ion_trans_dom	KCNB1 SCN2A SCN5A SCN7A	6.69e-04	114	65	4	IPR005821
Domain	Ion_trans	KCNB1 SCN2A SCN5A SCN7A	6.69e-04	114	65	4	PF00520
Domain	-	XPO5 MROH5 PKP2 UNC45A PPP4R4	1.05e-03	222	65	5	1.25.10.10
Domain	Myosin_N	MYH7B MYH15	1.22e-03	15	65	2	PF02736
Domain	Myosin_N	MYH7B MYH15	1.22e-03	15	65	2	IPR004009
Domain	Myosin_tail_1	MYH7B MYH15	1.76e-03	18	65	2	PF01576
Domain	Myosin_tail	MYH7B MYH15	1.76e-03	18	65	2	IPR002928
Domain	Furin_repeat	FRAS1 ERBB4	1.76e-03	18	65	2	IPR006212
Domain	FU	FRAS1 ERBB4	1.76e-03	18	65	2	SM00261
Domain	Myosin-like_IQ_dom	MYH7B MYH15	1.96e-03	19	65	2	IPR027401
Domain	-	MYH7B MYH15	1.96e-03	19	65	2	4.10.270.10
Domain	Arm	PKP2 UNC45A	5.20e-03	31	65	2	PF00514
Pathway	REACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION	ZMYM2 FGFR1 BCR	1.98e-04	31	52	3	M661
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN2A SCN5A SCN7A	1.98e-04	31	52	3	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN2A SCN5A SCN7A	2.18e-04	32	52	3	M27455
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	UBR4 USP24 ZMYM2 UNC45A HUWE1 BCR BIRC6 SPAG5 KNL1	1.11e-07	418	67	9	34709266
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PIKFYVE STK10 SEPHS2 FRAS1 IMPDH1 UBE4B UBR4 SCN5A FGFR1 HUWE1 BCR BIRC6	1.19e-06	1105	67	12	35748872
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	XPO5 UBR4 USP24 ZMYM2 SRP54 TAF2 KNL1	1.23e-06	282	67	7	23667531
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	DOCK5 STAG1 XPO5 CDC16 USP24 SRP54 UNC45A HUWE1 KNL1	1.75e-06	582	67	9	20467437
Pubmed	Functional proteomics mapping of a human signaling pathway.	STAG1 XPO5 UBR4 PDE4DIP PKP2 ZMYM2 UNC45A HUWE1 KNL1	1.98e-06	591	67	9	15231748
Pubmed	B-lymphoblastic leukemia/lymphoma associated with t(8;13)(p11;q12)/ ZMYM2 (ZNF198)-FGFR1 : rare case and review of the literature.	ZMYM2 FGFR1	3.66e-06	2	67	2	23594707
Pubmed	Characterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocation.	ZMYM2 FGFR1	3.66e-06	2	67	2	10480903
Pubmed	Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome.	FGFR1 BCR	3.66e-06	2	67	2	31525277
Pubmed	Brain-specific transcript variants of 5' and 3' ends of mouse VPS13A and VPS13C.	VPS13C VPS13A	3.66e-06	2	67	2	17196930
Pubmed	The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors.	ZMYM2 FGFR1	3.66e-06	2	67	2	12594223
Pubmed	Functional characterization of two rare BCR-FGFR1+ leukemias.	FGFR1 BCR	3.66e-06	2	67	2	31980503
Pubmed	ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5.	ZMYM2 FGFR1	3.66e-06	2	67	2	10935490
Pubmed	Fusion of the BCR and the fibroblast growth factor receptor-1 (FGFR1) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: the first fusion gene involving BCR but not ABL.	FGFR1 BCR	3.66e-06	2	67	2	11746971
Pubmed	Development of ZMYM2-FGFR1 driven AML in human CD34+ cells in immunocompromised mice.	ZMYM2 FGFR1	3.66e-06	2	67	2	27005999
Pubmed	Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase.	ZMYM2 FGFR1	3.66e-06	2	67	2	19506298
Pubmed	A case of 8p11 myeloproliferative syndrome with BCR-FGFR1 gene fusion presenting with trilineage acute leukemia/lymphoma, successfully treated by cord blood transplantation.	FGFR1 BCR	3.66e-06	2	67	2	23171834
Pubmed	Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.	SCN2A SCN5A	3.66e-06	2	67	2	16847056
Pubmed	Direct amplification of a single dissected chromosomal segment by polymerase chain reaction: a human brain sodium channel gene is on chromosome 2q22-q23.	SCN2A SCN7A	3.66e-06	2	67	2	1846440
Pubmed	Cellular and circuit models of increased resting-state network gamma activity in schizophrenia.	ERBB4 DTNBP1	1.10e-05	3	67	2	26577758
Pubmed	VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites.	VPS13C VPS13A	1.10e-05	3	67	2	30093493
Pubmed	Critical role of STAT5 activation in transformation mediated by ZNF198-FGFR1.	ZMYM2 FGFR1	1.10e-05	3	67	2	14660670
Pubmed	Calmodulin mediates Ca2+ sensitivity of sodium channels.	SCN2A SCN5A	1.10e-05	3	67	2	15316014
Pubmed	Evolution of sarcomeric myosin heavy chain genes: evidence from fish.	MYH7B MYH15	1.10e-05	3	67	2	15014174
Pubmed	TBC1D1 interacting proteins, VPS13A and VPS13C, regulate GLUT4 homeostasis in C2C12 myotubes.	VPS13C VPS13A	1.10e-05	3	67	2	33087848
Pubmed	Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.	ZMYM2 FGFR1	1.10e-05	3	67	2	21527531
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	DOCK5 AMER1 PPFIBP1 VPS13C VPS13A PKP2 HUWE1 BIRC6 DMXL1	1.78e-05	777	67	9	35844135
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SP100 SEPHS2 AMER1 STAG1 MYH7B UBR4 VPS13A MYH15 PHF14 KRBA2 FGFR1 PPP4R4	1.79e-05	1442	67	12	35575683
Pubmed	Analysis of the human VPS13 gene family.	VPS13C VPS13A	2.19e-05	4	67	2	15498460
Pubmed	Evolutionary implications of three novel members of the human sarcomeric myosin heavy chain gene family.	MYH7B MYH15	2.19e-05	4	67	2	11919279
Pubmed	Two novel/ancient myosins in mammalian skeletal muscles: MYH14/7b and MYH15 are expressed in extraocular muscles and muscle spindles.	MYH7B MYH15	2.19e-05	4	67	2	19948655
Pubmed	TRIM26 promotes non-small cell lung cancer survival by inducing PBX1 degradation.	UBR4 HUWE1	2.19e-05	4	67	2	37324936
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DOCK5 STK10 BMPR2 AMER1 UBE4B VPS13C SRP54 PHF14 HUWE1 BCR PPP4R4 DNAH1	2.45e-05	1489	67	12	28611215
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	AKAP6 STAG1 HUWE1 DMXL1	3.09e-05	92	67	4	15840729
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN5A	3.64e-05	5	67	2	17724025
Pubmed	Structural analyses of Ca²⁺/CaM interaction with NaV channel C-termini reveal mechanisms of calcium-dependent regulation.	SCN2A SCN5A	3.64e-05	5	67	2	25232683
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	HAUS8 ERBB4 BMPR2 AMER1 PPFIBP1 PKP2 UNC45A BCR PPP4R4	3.96e-05	861	67	9	36931259
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	NWD2 XPO5 PPFIBP1 BIRC6	4.82e-05	103	67	4	10574462
Pubmed	Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.	ZMYM2 FGFR1	5.46e-05	6	67	2	19658100
Pubmed	14-3-3 Integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1-transformed hematopoietic cells.	ZMYM2 FGFR1	5.46e-05	6	67	2	17389761
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	STK10 TAOK3 PPFIBP1 CDC16 PDE4DIP MYH15 FGFR1 BCR KNL1	6.07e-05	910	67	9	36736316
Pubmed	Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development.	SPAG5 KNL1	1.02e-04	8	67	2	35905187
Pubmed	Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytes.	AKAP6 PDE4DIP	1.02e-04	8	67	2	17923693
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	PIKFYVE HAUS8 PPFIBP1 BCR BIRC6	1.26e-04	251	67	5	29778605
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN2A SCN5A	1.30e-04	9	67	2	16382098
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN2A SCN5A	1.30e-04	9	67	2	15746173
Pubmed	Mouse TEX15 is essential for DNA double-strand break repair and chromosomal synapsis during male meiosis.	SYCP2 TEX15	1.63e-04	10	67	2	18283110
Pubmed	A proteomic analysis of ataxia telangiectasia-mutated (ATM)/ATM-Rad3-related (ATR) substrates identifies the ubiquitin-proteasome system as a regulator for DNA damage checkpoints.	TAOK3 HUWE1	1.63e-04	10	67	2	17478428
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AKAP6 CFAP91 CEP85 STAG1 UBE4B PPFIBP1 UBR4 PDE4DIP ZMYM2 HUWE1	1.67e-04	1285	67	10	35914814
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK5 STK10 ERBB4 NFE2L1 UBR4 DTNBP1	1.82e-04	430	67	6	35044719
Pubmed	Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.	UBE4B UBR4 USP24	1.95e-04	58	67	3	31067491
Pubmed	Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo.	SRP54 TAF2	1.99e-04	11	67	2	14729963
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	DOCK5 HAUS8 CFAP91 AMER1 XPO5 PPFIBP1 CDC16 DTNBP1 BCR SPAG5	2.09e-04	1321	67	10	27173435
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	CDC16 UBR4 ZMYM2 HUWE1	2.22e-04	153	67	4	26365490
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	UBR4 USP24 VPS13A ZMYM2 TAF2 PPP4R4 KNL1	2.27e-04	638	67	7	31182584
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	AMER1 PPFIBP1 CDC16 UBR4 PKP2 FGFR1 HUWE1	2.29e-04	639	67	7	23443559
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	HAUS8 AMER1 PPFIBP1 VPS13C TAF2 UNC45A BCR SPAG5	2.30e-04	853	67	8	28718761
Pubmed	UBXD7 binds multiple ubiquitin ligases and implicates p97 in HIF1alpha turnover.	UBE4B UBR4 HUWE1	2.38e-04	62	67	3	18775313
Pubmed	p120cbl is a major substrate of tyrosine phosphorylation upon B cell antigen receptor stimulation and interacts in vivo with Fyn and Syk tyrosine kinases, Grb2 and Shc adaptors, and the p85 subunit of phosphatidylinositol 3-kinase.	SCN5A BCR	2.38e-04	12	67	2	8621719
Pubmed	Syndactyly in a novel Fras1(rdf) mutant results from interruption of signals for interdigital apoptosis.	FRAS1 BMPR2	2.38e-04	12	67	2	26813283
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN2A SCN5A	2.38e-04	12	67	2	30175250
Pubmed	EB1-binding-myomegalin protein complex promotes centrosomal microtubules functions.	PDE4DIP BIRC6 SPAG5	2.50e-04	63	67	3	29162697
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DOCK5 FRAS1 TAOK3 CEP85 PPFIBP1 BCR SPAG5	2.54e-04	650	67	7	38777146
Pubmed	Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project.	MYH7B MYH15	2.81e-04	13	67	2	22443383
Pubmed	Transcription factor ETV1 is essential for rapid conduction in the heart.	ERBB4 SCN5A	2.81e-04	13	67	2	27775552
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN2A SCN5A	2.81e-04	13	67	2	15123669
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	STK10 SP100 CEP85 STAG1 SPAG5 KNL1	3.00e-04	472	67	6	38943005
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ERBB4 KCNB1 CDC16 UBR4 PDE4DIP USP24 HUWE1 BCR BIRC6	3.26e-04	1139	67	9	36417873
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	UBR4 HUWE1	3.28e-04	14	67	2	27626314
Pubmed	Characterization of vertebrate cohesin complexes and their regulation in prophase.	STAG1 CDC16	3.28e-04	14	67	2	11076961
Pubmed	Confirmation of quantitative trait loci for alcohol preference in mice.	SCN2A SCN7A	3.78e-04	15	67	2	9726281
Pubmed	USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia.	IMPDH1 XPO5 USP24	3.86e-04	73	67	3	30224337
Pubmed	Jun and JunD-dependent functions in cell proliferation and stress response.	ERBB4 NFE2L1	4.88e-04	17	67	2	20300111
Pubmed	Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.	CDC16 UBR4	4.88e-04	17	67	2	29033132
Pubmed	Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads.	STAG1 CDC16	4.88e-04	17	67	2	21043528
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	STAG1 UBE4B UBR4 ZMYM2 UNC45A	5.17e-04	341	67	5	32971831
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	PIKFYVE HAUS8 VPS13C HUWE1 BCR BIRC6 KNL1	5.22e-04	733	67	7	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DOCK5 VPS13C UBR4 VPS13A PHF14 HUWE1 BIRC6	5.34e-04	736	67	7	29676528
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	TAOK3 UBR4 USP24 HUWE1 BIRC6	5.37e-04	344	67	5	30333137
Pubmed	Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.	KCNB1 SCN2A	5.48e-04	18	67	2	37321992
Pubmed	Autoregulation of the 26S proteasome by in situ ubiquitination.	UBR4 HUWE1	6.12e-04	19	67	2	24743594
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NWD2 UBR4 HUWE1	6.45e-04	87	67	3	12465718
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	CEP85 CDC16 USP24 TAF2 UNC45A HUWE1	6.65e-04	549	67	6	38280479
Pubmed	STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis.	SYCP2 STAG1	6.79e-04	20	67	2	24797475
Pubmed	Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.	UBE4B VPS13C VPS13A UNC45A	7.22e-04	209	67	4	26389662
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	PPFIBP1 SRP54 BCR SPAG5	7.22e-04	209	67	4	36779422
Pubmed	Specification of SUMO1- and SUMO2-interacting motifs.	SP100 ZMYM2	8.24e-04	22	67	2	16524884
Pubmed	Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.	USP24 HUWE1	8.24e-04	22	67	2	37225996
Pubmed	Gene-environment interaction impacts on heart development and embryo survival.	SCN5A FGFR1	8.24e-04	22	67	2	30787001
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	PIKFYVE CEP85 ZMYM2 HUWE1 BCR KNL1	9.49e-04	588	67	6	38580884
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	AKAP6 XPO5 PPFIBP1 BIRC6	9.50e-04	225	67	4	12168954
Pubmed	Brugada Syndrome	SCN5A PKP2	9.82e-04	24	67	2	20301690
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ERBB4 FGFR1 BCR	9.95e-04	101	67	3	23382219
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	HUWE1 PPP4R4 KNL1	9.95e-04	101	67	3	10997877
Pubmed	Proximity interactions among centrosome components identify regulators of centriole duplication.	HAUS8 CEP85 SPAG5	9.95e-04	101	67	3	24613305
Pubmed	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PIKFYVE VPS13A MYH15	1.02e-03	102	67	3	10231032
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	AMER1 NFE2L1 HUWE1 KNL1	1.06e-03	232	67	4	25515538
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	ERBB4 FGFR1	1.07e-03	25	67	2	15254900
Pubmed	A chemical tool for blue light-inducible proximity photo-crosslinking in live cells.	CEP85 USP24	1.07e-03	25	67	2	35211260
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	HAUS8 AMER1 VPS13A UNC45A HUWE1 BCR	1.11e-03	606	67	6	36538041
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	AKAP6 TAOK3 AMER1 NFE2L1 SRP54 ACCSL HUWE1 SPAG5	1.11e-03	1084	67	8	11544199
Interaction	DUSP16 interactions	HAUS8 ERBB4 AMER1 CEP85 UBE4B VPS13C SPAG5 KNL1	1.17e-06	237	67	8	int:DUSP16
Interaction	CALM1 interactions	AKAP6 KCNB1 STAG1 VPS13C SCN2A UBR4 PDE4DIP SCN5A VPS13A HUWE1 DMXL1	6.30e-06	626	67	11	int:CALM1
Interaction	PHF21A interactions	UBR4 USP24 ZMYM2 HUWE1 BCR BIRC6 SPAG5 KNL1	1.77e-05	343	67	8	int:PHF21A
Interaction	RCOR1 interactions	SP100 UBR4 USP24 ZMYM2 UNC45A HUWE1 BCR BIRC6 KNL1	3.60e-05	494	67	9	int:RCOR1
Interaction	AKAP1 interactions	CFAP91 VPS13C CDC16 UBR4 VPS13A PKP2 UNC45A HUWE1 BIRC6	4.14e-05	503	67	9	int:AKAP1
Interaction	FES interactions	ERBB4 PDE4DIP FGFR1 BCR	5.05e-05	61	67	4	int:FES
Interaction	TOP3B interactions	PIKFYVE STK10 SEPHS2 FRAS1 IMPDH1 UBE4B XPO5 UBR4 SCN5A PKP2 FGFR1 UNC45A HUWE1 BCR BIRC6	7.63e-05	1470	67	15	int:TOP3B
Interaction	ITGB2 interactions	TAOK3 UBR4 USP24 HUWE1 BIRC6	7.79e-05	132	67	5	int:ITGB2
Interaction	PTPRM interactions	PPFIBP1 UNC45A HUWE1 DTNBP1	9.68e-05	72	67	4	int:PTPRM
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN2A SCN5A	1.88e-04	9	42	2	1203
GeneFamily	Myosin heavy chains	MYH7B MYH15	5.43e-04	15	42	2	1098
Coexpression	GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP	BMPR2 CEP85 CDC16 ZMYM2 UNC45A BCR	1.04e-05	200	65	6	M5617
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	PIKFYVE STK10 SP100 TAOK3 STAG1 CDC16 USP24 VPS13A ZMYM2 PHF14	4.61e-05	856	65	10	M4500
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	BMPR2 UBE4B VPS13C USP24 BIRC6	8.55e-05	180	65	5	M8239
Coexpression	FAN_EMBRYONIC_CTX_IN_3_INTERNEURON	ERBB4 PDE4DIP	9.03e-05	6	65	2	M39029
Coexpression	GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN	STAG1 UBE4B VPS13C TAF2 SPAG5	9.98e-05	186	65	5	M8175
Coexpression	GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	HAUS8 STAG1 UBE4B ZMYM2 BCR	1.22e-04	194	65	5	M7467
Coexpression	GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN	PIKFYVE STK10 SP100 TAOK3 DMXL1	1.31e-04	197	65	5	M3255
Coexpression	GSE3982_EOSINOPHIL_VS_BASOPHIL_DN	PIKFYVE SYCP2 UBE4B SRP54 UNC45A	1.37e-04	199	65	5	M5414
Coexpression	GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN	DOCK5 SEPHS2 SCN2A SRP54 UNC45A	1.40e-04	200	65	5	M7993
Coexpression	GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_DN	DOCK5 SEPHS2 XPO5 SASH3 PKP2	1.40e-04	200	65	5	M4057
Coexpression	GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP	UBR4 USP24 VPS13A SRP54 TAF2	1.40e-04	200	65	5	M9889
Coexpression	GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP	MYH7B PHF14 PPP1R17 SPAG5 KNL1	1.40e-04	200	65	5	M6057
Coexpression	GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_UP	UNC45A ACCSL C8A BCR SPAG5	1.40e-04	200	65	5	M5627
Coexpression	GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP	PPP1R17 C8A DTNBP1 BCR PPP4R4	1.40e-04	200	65	5	M6996
Coexpression	FEKIR_HEPARG_SPHERE_VS_HEPARG_DN	FMO3 KCNB1 PDE4DIP	1.56e-04	42	65	3	M48359
Coexpression	ZENG_GU_ICB_CONTROL_METAGENE_3_PRECICTIVE_ICB_RESPONSE	VPS13C VPS13A HUWE1 BIRC6 SPAG5	1.80e-04	211	65	5	MM17081
Coexpression	DESCARTES_ORGANOGENESIS_SENSORY_NEURONS	PDE4DIP SCN5A SCN7A PPP1R17	2.00e-04	116	65	4	MM3649
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000	PIKFYVE VPS13A TEX15 HUWE1 FBXO47 DMXL1	2.11e-05	187	64	6	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k3_1000
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PPFIBP1 PDE4DIP SCN5A PKP2	1.51e-08	190	67	7	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	AKAP6 FRAS1 ERBB4 MYH7B PDE4DIP SCN5A PKP2	1.74e-08	194	67	7	c3535f7cc0076653c72db582047cff053c322397
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PPFIBP1 SCN5A PKP2	3.85e-07	187	67	6	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PPFIBP1 PDE4DIP PKP2	4.09e-07	189	67	6	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PPFIBP1 PDE4DIP PKP2	4.22e-07	190	67	6	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PDE4DIP SCN5A PKP2	4.35e-07	191	67	6	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 ERBB4 MYH7B PDE4DIP SCN5A PKP2	4.92e-07	195	67	6	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 ERBB4 MYH7B PDE4DIP SCN5A PKP2	4.92e-07	195	67	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 MYH7B PDE4DIP SCN5A PKP2	5.80e-06	170	67	5	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 BMPR2 STAG1 VPS13C SRP54	6.87e-06	176	67	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SP100 BMPR2 STAG1 VPS13C SRP54	7.25e-06	178	67	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ERBB4 SCN2A SCN7A USP24	7.45e-06	179	67	5	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 MYH7B PDE4DIP SCN5A PKP2	7.87e-06	181	67	5	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SYCP2 SCN2A MYH15 DNAH1	8.52e-06	184	67	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SYCP2 SCN2A MYH15 DNAH1	8.52e-06	184	67	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SYCP2 SCN2A MYH15 DNAH1	8.52e-06	184	67	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 MYH7B PDE4DIP SCN5A PKP2	8.75e-06	185	67	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	AKAP6 MYH7B PPFIBP1 PDE4DIP PKP2	8.75e-06	185	67	5	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 MYH7B SCN5A PKP2 FRMPD3	9.45e-06	188	67	5	4db566f3f708e66730aa9e16f4d73d91dc534177
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 MYH7B SCN5A PKP2 FRMPD3	9.45e-06	188	67	5	6704b92991ad8c0a910e9f36cd33d00bd26dcb8f
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B SCN5A PKP2	9.70e-06	189	67	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ERBB4 SCN2A SCN7A USP24	9.70e-06	189	67	5	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ERBB4 SCN2A SCN7A USP24	9.70e-06	189	67	5	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PDE4DIP PKP2	1.02e-05	191	67	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PDE4DIP PKP2	1.05e-05	192	67	5	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 ERBB4 PDE4DIP SCN5A PKP2	1.07e-05	193	67	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 STAG1 VPS13C SCN7A SRP54	1.13e-05	195	67	5	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	LV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AKAP6 MYH7B PDE4DIP PKP2	4.43e-05	130	67	4	a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ERBB4 SCN2A SCN7A	5.43e-05	137	67	4	85b3a98039c1f68addad0334aa5b2584f6045aaa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ERBB4 SCN2A SCN7A	6.25e-05	142	67	4	5b6b0c611c83b23ef7289854a515b78f6cf84500
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-9\|TCGA-Liver / Sample_Type by Project: Shred V9	SEPHS2 NWD2 SPAG5 KNL1	7.33e-05	148	67	4	683b2b80ee389469d948aaf6a77632b24f56e989
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 SCN5A SCN7A PKP2	7.53e-05	149	67	4	98ae408d2d0347865875ff8bbd89d359decea526
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP2 TEX15 PPP1R17 ACCSL	7.73e-05	150	67	4	47ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ERBB4 SCN5A SCN7A FRMPD3	8.77e-05	155	67	4	105d59d8a1bb8cb37eef2c1767d737b2108ac7c5
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STK10 SASH3 VPS13C KNL1	9.22e-05	157	67	4	904cd98ae85ed6459e0663f077ac462842bf12df
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPFIBP1 SCN5A FRMPD3 BCR	1.12e-04	165	67	4	347b59aa625a8a960828b8620824d8ac48990e07
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPFIBP1 SCN5A FRMPD3 BCR	1.12e-04	165	67	4	507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCell	PND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPFIBP1 SCN5A FRMPD3 BCR	1.12e-04	165	67	4	39a25be081a5d59c7cf107a997d352793d5025fb
ToppCell	PND03-Endothelial-Endothelial_lymphatic\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPFIBP1 SCN5A FRMPD3 BCR	1.12e-04	165	67	4	1890f9c33b0c5b381d57f97042da2610a093a6de
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-2_VIP_RPL41P3\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SCN5A SCN7A FRMPD3	1.20e-04	168	67	4	0a7f81266576409560396356d16989e944865844
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SCN5A PKP2 C8A	1.22e-04	169	67	4	6a2ef66d7ff69a92e8c62759482e823a07352440
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 SCN5A NMRK1 PKP2	1.25e-04	170	67	4	14aa86a4f526ed6986afcb28c49225522055550c
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HAUS8 CIB3 SRP54 RAI2	1.34e-04	173	67	4	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HAUS8 AMER1 CEP85 SPAG5	1.34e-04	173	67	4	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HAUS8 AMER1 CEP85 SPAG5	1.34e-04	173	67	4	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP6 KCNB1 SCN5A KRBA2	1.40e-04	175	67	4	d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ERBB4 SCN2A SCN7A	1.40e-04	175	67	4	787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	AKAP6 KCNB1 SCN5A KRBA2	1.40e-04	175	67	4	454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ERBB4 SCN5A PKP2 PPP1R17	1.43e-04	176	67	4	05ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 PDE4DIP SCN5A PKP2	1.43e-04	176	67	4	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NWD2 PPFIBP1 SCN7A FGFR1	1.46e-04	177	67	4	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP91 SASH3 SCN7A DNAH1	1.49e-04	178	67	4	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP91 SASH3 SCN7A DNAH1	1.49e-04	178	67	4	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SCN5A SCN7A PKP2	1.53e-04	179	67	4	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	LV\|World / Chamber and Cluster_Paper	AKAP6 MYH7B PPFIBP1 PKP2	1.56e-04	180	67	4	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	RV\|World / Chamber and Cluster_Paper	AKAP6 MYH7B PPFIBP1 PKP2	1.59e-04	181	67	4	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	lymphoid-NK_cell-TNFRSF18+IL7R+_NK_cell\|World / Lineage, cell class and subclass	IMPDH1 SCN2A FGFR1 FRMPD3	1.59e-04	181	67	4	0d096d7d557fd2e71b35e41816e11d7e83cd9210
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SCN2A SCN7A USP24	1.63e-04	182	67	4	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 ERBB4 SCN2A USP24	1.66e-04	183	67	4	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEPHS2 VPS13A SPAG5 KNL1	1.70e-04	184	67	4	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEPHS2 VPS13A SPAG5 KNL1	1.70e-04	184	67	4	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	SEPHS2 VPS13A SPAG5 KNL1	1.70e-04	184	67	4	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEPHS2 VPS13A SPAG5 KNL1	1.70e-04	184	67	4	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEPHS2 VPS13A SPAG5 KNL1	1.70e-04	184	67	4	d31d4116d1d196633784863781fa45673607a421
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	AKAP6 MYH7B PDE4DIP PKP2	1.70e-04	184	67	4	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	SEPHS2 VPS13A SPAG5 KNL1	1.70e-04	184	67	4	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	SEPHS2 VPS13A SPAG5 KNL1	1.70e-04	184	67	4	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 MYH7B SCN5A PKP2	1.70e-04	184	67	4	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SCN5A PKP2 FRMPD3	1.73e-04	185	67	4	027020754dbf71b0034791f9a34ae795e3b85f81
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SCN7A PKP2 FRMPD3	1.73e-04	185	67	4	08fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCell	5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYCP2 SCN5A FGFR1 RAI2	1.77e-04	186	67	4	f07e0c0d9c80ac9d8d679950e7d0c812becb85a3
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	BMPR2 AMER1 STAG1 BIRC6	1.77e-04	186	67	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	facs-Heart-Unknown-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 MYH7B SCN5A FRMPD3	1.81e-04	187	67	4	0ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCell	lymphoid-NK_cell-TNFRSF18+IL7R+_NK_cell\|lymphoid / Lineage, cell class and subclass	IMPDH1 SCN2A FGFR1 FRMPD3	1.81e-04	187	67	4	99dfa50f6325b0d66d23ee8dcaa6437e7161628a
ToppCell	facs-Heart-Unknown\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 MYH7B SCN5A FRMPD3	1.81e-04	187	67	4	362e56426a568423a81e8a30e3ecf99b76135843
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SCN2A SCN7A USP24	1.81e-04	187	67	4	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	facs-Heart-Unknown-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 MYH7B SCN5A FRMPD3	1.81e-04	187	67	4	c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AKAP6 ERBB4 PDE4DIP SCN5A	1.84e-04	188	67	4	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	VPS13C USP24 HUWE1 BIRC6	1.84e-04	188	67	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	AKAP6 MYH7B PPFIBP1 PKP2	1.84e-04	188	67	4	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 ERBB4 SCN5A PKP2	1.88e-04	189	67	4	e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	SP100 BMPR2 PPFIBP1 BCR	1.88e-04	189	67	4	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SCN2A SCN7A USP24	1.88e-04	189	67	4	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	facs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 ERBB4 SCN5A PKP2	1.88e-04	189	67	4	b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIKFYVE USP24 DMXL1 KNL1	1.92e-04	190	67	4	ed100e271aac82806f59e0c613ccda63f59100c1
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	AKAP6 ERBB4 MYH7B PDE4DIP	1.92e-04	190	67	4	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	AKAP6 MYH7B SCN5A PKP2	1.92e-04	190	67	4	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	COVID-19-Heart-CM_4\|Heart / Disease (COVID-19 only), tissue and cell type	AKAP6 ERBB4 CEP85 PKP2	1.92e-04	190	67	4	3729648a17093b438398b82e32bbccc3af7b8c5d
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 PDE4DIP SCN7A SRP54	1.92e-04	190	67	4	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 SCN5A SCN7A PKP2	1.96e-04	191	67	4	764c3a8829ae1253a0790744138266e81fc075ec
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BMPR2 STAG1 VPS13C SCN7A	1.96e-04	191	67	4	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 FRAS1 PDE4DIP PKP2	2.00e-04	192	67	4	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP6 FRAS1 PDE4DIP PKP2	2.00e-04	192	67	4	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FRAS1 NWD2 PPP1R17 ACCSL	2.04e-04	193	67	4	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	SP100 BMPR2 PPFIBP1 BCR	2.04e-04	193	67	4	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	HAUS8 CEP85 SPAG5 KNL1	2.08e-04	194	67	4	f9070035553bc68106a9e0bdf4b507715a138aba
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	AKAP6 FRAS1 ERBB4 PDE4DIP	2.08e-04	194	67	4	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	Control-Myeloid-ncMonocyte\|Control / Disease state, Lineage and Cell class	DOCK5 STK10 PKP2 PPP1R17	2.12e-04	195	67	4	fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 VPS13C VPS13A HUWE1	2.12e-04	195	67	4	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNB1 VPS13C VPS13A HUWE1	2.12e-04	195	67	4	7796ea9247f4c63762f0de8490fed08b9717fa23
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN2A SCN5A SCN7A	1.33e-06	10	67	3	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN2A SCN5A SCN7A	1.33e-06	10	67	3	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN2A SCN5A SCN7A	2.43e-06	12	67	3	DOID:0060170 (implicated_via_orthology)
Disease	Myeloproliferative disease	ZMYM2 FGFR1 BCR	2.43e-06	12	67	3	C0027022
Disease	Parkinson's disease 23 (implicated_via_orthology)	VPS13C VPS13A	5.08e-06	2	67	2	DOID:0060896 (implicated_via_orthology)
Disease	choreaacanthocytosis (implicated_via_orthology)	VPS13C VPS13A	5.08e-06	2	67	2	DOID:0050766 (implicated_via_orthology)
Disease	Arrhythmogenic Right Ventricular Dysplasia	SCN5A PKP2	1.52e-05	3	67	2	C0349788
Disease	autosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)	VPS13C VPS13A	1.52e-05	3	67	2	DOID:0111611 (implicated_via_orthology)
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13A	1.52e-05	3	67	2	DOID:0111590 (implicated_via_orthology)
Disease	Paroxysmal atrial fibrillation	AKAP6 ERBB4 UBE4B SCN5A PKP2	2.87e-05	156	67	5	C0235480
Disease	familial atrial fibrillation	AKAP6 ERBB4 UBE4B SCN5A PKP2	2.87e-05	156	67	5	C3468561
Disease	Persistent atrial fibrillation	AKAP6 ERBB4 UBE4B SCN5A PKP2	2.87e-05	156	67	5	C2585653
Disease	Atrial Fibrillation	AKAP6 ERBB4 UBE4B SCN5A PKP2	3.24e-05	160	67	5	C0004238
Disease	urate measurement, bone density	AKAP6 DOCK5 FRAS1 ERBB4 UBE4B PPFIBP1 DTNBP1 DNAH1	7.87e-05	619	67	8	EFO_0003923, EFO_0004531
Disease	cerebellar ataxia (implicated_via_orthology)	VPS13C VPS13A	1.41e-04	8	67	2	DOID:0050753 (implicated_via_orthology)
Disease	dilated cardiomyopathy 1S (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:0110454 (implicated_via_orthology)
Disease	autosomal dominant hyaline body myopathy (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:0111269 (implicated_via_orthology)
Disease	congenital myopathy 6 (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:0080719 (implicated_via_orthology)
Disease	distal arthrogryposis type 2B3 (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:0111602 (implicated_via_orthology)
Disease	inclusion body myositis (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:3429 (implicated_via_orthology)
Disease	distal arthrogryposis type 2A (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:0111605 (implicated_via_orthology)
Disease	familial hypertrophic cardiomyopathy (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:0080326 (implicated_via_orthology)
Disease	distal arthrogryposis type 1 (implicated_via_orthology)	MYH7B MYH15	2.26e-04	10	67	2	DOID:0111596 (implicated_via_orthology)
Disease	distal myopathy (implicated_via_orthology)	MYH7B MYH15	3.30e-04	12	67	2	DOID:11720 (implicated_via_orthology)
Disease	myotonia congenita (implicated_via_orthology)	MYH7B MYH15	3.30e-04	12	67	2	DOID:2106 (implicated_via_orthology)
Disease	Brugada Syndrome 1	SCN5A PKP2	3.90e-04	13	67	2	C4551804
Disease	restrictive cardiomyopathy (implicated_via_orthology)	MYH7B MYH15	3.90e-04	13	67	2	DOID:397 (implicated_via_orthology)
Disease	Left ventricular noncompaction	MYH7B PKP2	4.54e-04	14	67	2	C1960469
Disease	distal arthrogryposis (implicated_via_orthology)	MYH7B MYH15	5.23e-04	15	67	2	DOID:0050646 (implicated_via_orthology)
Disease	cardiomyopathy (implicated_via_orthology)	ERBB4 MYH7B MYH15	5.73e-04	71	67	3	DOID:0050700 (implicated_via_orthology)
Disease	obsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa	AKAP6 KCNB1 STAG1 FGFR1	1.12e-03	200	67	4	EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Disease	nucleus accumbens volume	SP100 BIRC6	1.14e-03	22	67	2	EFO_0006931
Disease	insular cortex volume measurement	VPS13C FBXO47	1.25e-03	23	67	2	EFO_0010309
Disease	cognitive function measurement, self reported educational attainment	AKAP6 ERBB4 MYH15 BIRC6 KNL1	1.29e-03	355	67	5	EFO_0004784, EFO_0008354
Disease	airway responsiveness measurement	USP24 MYH15	1.36e-03	24	67	2	EFO_0006897
Disease	Brugada Syndrome (disorder)	SCN5A PKP2	1.36e-03	24	67	2	C1142166
Disease	atrial fibrillation	AKAP6 ERBB4 UBE4B SCN5A PKP2	1.56e-03	371	67	5	EFO_0000275
Disease	bipolar disorder	AKAP6 KCNB1 NFE2L1 SCN2A FGFR1 HUWE1	1.98e-03	577	67	6	MONDO_0004985
Disease	Bilateral Wilms Tumor	AMER1 XPO5	1.98e-03	29	67	2	C2930471

Protein segments in the cluster

Peptide	Gene	Start	Entry
CMDLMTERLQESDMN	ACCSL	181	Q4AC99
ANVEFMDEALIMASM	ERBB4	761	Q15303
EQQAELMLKMMSTLE	BIRC6	2576	Q9NR09
DDIMLDEGMLQSLME	C8A	306	P07357
DVSVMMSEMDVNAIA	BCR	1111	P11274
IIAEQDMDSMTDSMA	AMER1	331	Q5JTC6
LSRMEQMSLMALADT	DMXL1	1501	Q9Y485
TLEMTSNEEEEMEMA	CFAP91	481	Q7Z4T9
TMAKMGLSEMELEDV	NWD2	666	Q9ULI1
MEMQAMEVNTSASEI	NFE2L1	321	Q14494
MDDLQSQNLSMDMTD	RAI2	1	Q9Y5P3
TCTLPSMEDMMNDIN	FMO3	396	P31513
FLMDPNTSDMSLAEM	FRAS1	3671	Q86XX4
MMSDASDMLAAALEQ	PPFIBP1	1	Q86W92
DLLEDMAMMTHLNEA	MYH7B	126	A7E2Y1
ELACMDTYEMEIMTL	OR4K1	186	Q8NGD4
DMLEQMDLMDISDQE	DTNBP1	236	Q96EV8
EKEMMLQNLMTTSED	KNL1	541	Q8NG31
MEAMENSMAQRSDLL	GDPD3	56	Q7L5L3
DLSEAMEMMESQTLL	HAUS8	141	Q9BT25
MEMMESQTLLLTLLS	HAUS8	146	Q9BT25
DLSMSEEDQMMRAIA	HUWE1	1366	Q7Z6Z7
SSDMEADMAMETLPD	PHF14	781	O94880
DTVTEADMAIAMALM	IMPDH1	71	P20839
MTQGDLVMSMDQLLT	PIKFYVE	786	Q9Y2I7
EAMTMMFEVQDLAVA	DNAH1	1981	Q9P2D7
LEETFEIEMNESDMM	CDC16	596	Q13042
MMEEMCALSFSQELD	KCNB1	106	Q14721
DTLDALFNIMMEMSD	DOCK5	671	Q9H7D0
TEKDLSDLISEMEMM	FGFR1	521	P11362
ETNSSELTDMSEMMS	FRMPD3	806	Q5JV73
IPSMESTLNQSAMME	CEP85	181	Q6P2H3
MNMMEAAASEPSLDL	BMPR2	186	Q13873
MEMLQSIMSGDRDED	FBXO47	406	Q5MNV8
MMVKALSEEMADTLE	SASH3	91	O75995
SNASEMEMEISNMRE	KRBA2	96	Q6ZNG9
RTMEALDFMLQSLIM	MROH5	561	Q6ZUA9
DVLEALNMEKMMSAI	NMRK1	56	Q9NWW6
MEESLAEMSIMTTEL	SPAG5	966	Q96R06
MTIMDSMNDQELDST	SRP54	376	P61011
TVLELDRMEMSMDAF	PPP4R4	671	Q6NUP7
LMNGEEVDMDLSAMD	TAF2	606	Q6P1X5
EFEMIEDMAMLTHLN	MYH15	101	Q9Y2K3
NMVTMMVETDDQSPE	SCN5A	1541	Q14524
SMQEVMDESSSELVM	TAOK3	366	Q9H2K8
MDESSSELVMMHDDE	TAOK3	371	Q9H2K8
TTAIELMDFMLSSMV	OR6J1	191	Q8NGC5
LVMDSHDLMMSEEQQ	AKAP6	981	Q13023
MTLDNFLDMFSVMSE	CIB3	86	Q96Q77
MMSTEQMQPLELSED	PPP1R17	1	O96001
DNMLMLLSVSQSMSE	SEPHS2	171	Q99611
FSIMELLESVDMMAQ	VPS13A	296	Q96RL7
LSNQEMLILMSSMGE	SYCP2	191	Q9BX26
LMEVLMMSTQTRDEN	UBE4B	206	O95155
MRDMLAQCESNMSEL	STK10	866	O94804
TESSQASDMMDTMDV	SP100	506	P23497
VTMMVETDDQSQEMT	SCN2A	1546	Q99250
EEMMATEVTPSAMAE	XPO5	996	Q9HAV4
VMMSSRSQLEDMNEE	STAG1	1201	Q8WVM7
ALNAELMETSMTDMS	VPS13C	3306	Q709C8
TVFSEMNIMMLTISD	TLR6	326	Q9Y2C9
LDTELLTMTDMMSED	ZMYM2	946	Q9UBW7
MESEEEQHMTTLLCM	USP24	1	Q9UPU5
IAMMIDTDVQSLQMS	SCN7A	1266	Q01118
AVDTLVELQMMMETI	TEX15	1686	Q9BXT5
ETQDMLLEMLEDMTT	UBR4	4286	Q5T4S7
NADMEMTLERAVSML	PKP2	346	Q99959
IASTLMESEMMEILS	UNC45A	896	Q9H3U1
ESQMELSALQSMMAV	PDE4DIP	771	Q5VU43