Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein kinase activity

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN PEAK3 BRAF PDIK1L GUCY2D ALPK3 PRKDC PINK1

1.89e-0460013313GO:0004672
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR2 ITPR3

2.19e-04181333GO:0015278
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2

2.62e-0441332GO:0005219
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN PEAK3 BRAF PIK3CD PDIK1L GUCY2D ALPK3 PRKDC PINK1

2.76e-0470913314GO:0016773
GeneOntologyMolecularFunctionactin binding

XIRP1 MYO5A LRRK2 SLC4A1 SPTBN4 WASH3P CORO2B MAP1S XIRP2 SYNE2 GMFB

3.68e-0447913311GO:0003779
GeneOntologyMolecularFunctionankyrin binding

OBSCN SLC4A1 SPTBN4

4.64e-04231333GO:0030506
GeneOntologyMolecularFunctionkinase activity

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN PEAK3 BRAF PIK3CD PDIK1L GUCY2D ALPK3 PRKDC PINK1

5.82e-0476413314GO:0016301
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2

6.49e-0461332GO:0048763
GeneOntologyMolecularFunctionprotein serine kinase activity

CDK20 CDKL2 LRRK2 OBSCN BRAF PDIK1L ALPK3 PRKDC PINK1

7.40e-043631339GO:0106310
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX17 DNAH10 KIF1A TOR2A PSMC2 KIF7 NLRP10 SMARCA4 DDX53 ATP2B3

7.51e-0444113310GO:0016887
GeneOntologyMolecularFunctioncytoskeletal protein binding

XIRP1 KIF1A MYO5A LRRK2 OBSCN SLC4A1 KIF7 SPTBN4 PROM1 WASH3P CORO2B DLC1 MAP1S XIRP2 SYNE2 GMFB HOOK2

1.02e-03109913317GO:0008092
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR2 ITPR3

1.13e-03311333GO:0099604
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

RYR1 RYR2 ITPR3

1.36e-03331333GO:0005217
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN REV3L PEAK3 BRAF PIK3CD PDIK1L GUCY2D ALPK3 PRKDC PINK1

1.47e-0393813315GO:0016772
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor binding

APOB WASH3P AP2M1

1.49e-03341333GO:0050750
GeneOntologyBiologicalProcessheart morphogenesis

XIRP1 PCDHA10 PPP1R13L RYR1 RYR2 DLC1 XIRP2 DCHS1 SMARCA4 ROBO2 SMARCD3 ASB2

9.99e-0732113112GO:0003007
GeneOntologyBiologicalProcessactin filament-based process

ADCY10 XIRP1 MYO5A CARMIL3 SH3KBP1 OBSCN PEAK3 RYR2 EHD2 SPTBN4 CFLAR WASH3P CORO2B DLC1 BRAF XIRP2 SYNE2 GMFB FGD5 ASB2

1.25e-0691213120GO:0030029
GeneOntologyBiologicalProcessanimal organ morphogenesis

XIRP1 MYO5A ROR2 LRRK2 PCDHA10 PPP1R13L TYMP ITGB4 RYR1 RYR2 RING1 GREB1L CFLAR PROM1 DLC1 BRAF XIRP2 DCHS1 SMARCA4 ROBO2 SMARCD3 PAX2 PAX5 ASB2

1.34e-06126913124GO:0009887
GeneOntologyBiologicalProcessheart development

ERBB2 XIRP1 PCDHA10 PPP1R13L RYR1 RYR2 KIF7 GREB1L FREM2 DLC1 XIRP2 ALPK3 DCHS1 SMARCA4 ROBO2 SMARCD3 PRKDC ASB2

1.45e-0675713118GO:0007507
GeneOntologyBiologicalProcesscell junction organization

ERBB2 LRFN1 KIF1A MYO5A DSG1 CARMIL3 ROR2 LRRK2 ITGB4 STAU1 SPTBN4 CORO2B DLC1 PTPRD XIRP2 LRFN5 ROBO2 PATJ CDH6 MPP7

3.41e-0697413120GO:0034330
GeneOntologyBiologicalProcesscardiac chamber development

PCDHA10 PPP1R13L RYR2 KIF7 GREB1L XIRP2 SMARCA4 ROBO2 SMARCD3

8.65e-062121319GO:0003205
GeneOntologyBiologicalProcesscardiac ventricle development

PCDHA10 PPP1R13L RYR2 GREB1L XIRP2 SMARCA4 ROBO2 SMARCD3

8.88e-061611318GO:0003231
GeneOntologyBiologicalProcessnucleosome disassembly

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.04e-05221314GO:0006337
GeneOntologyBiologicalProcessregulation of organelle organization

ADCY10 LRFN1 MYO5A CARMIL3 LRRK2 RMI2 PEAK3 SPTBN4 WASH3P VPS13D CORO2B DLC1 PTPRD MAP1S BRAF XIRP2 SYNE2 SMARCA4 SMARCD1 SMARCD2 GMFB SMARCD3 PINK1

1.17e-05134213123GO:0033043
GeneOntologyBiologicalProcessactin cytoskeleton organization

XIRP1 MYO5A CARMIL3 SH3KBP1 OBSCN PEAK3 EHD2 SPTBN4 CFLAR WASH3P CORO2B DLC1 BRAF XIRP2 GMFB FGD5 ASB2

1.34e-0580313117GO:0030036
GeneOntologyBiologicalProcessprotein-DNA complex disassembly

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.50e-05241314GO:0032986
GeneOntologyBiologicalProcessregulation of nucleotide-excision repair

SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.26e-05291314GO:2000819
GeneOntologyBiologicalProcessregulation of double-strand break repair

RMI2 SMARCA4 SMARCD1 SMARCD2 SMARCD3 PRKDC TP53BP1

4.14e-051461317GO:2000779
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

ERBB2 RC3H1 BRAF SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC

5.18e-052661319GO:0045619
GeneOntologyBiologicalProcesscell morphogenesis

ADCY10 ERBB2 KIF1A SH3KBP1 LRRK2 SPART PEAK3 SPTBN4 DLC1 PTPRD MAP1S BRAF SMARCA4 ROBO2 MAEL FGD5 PAX2 PRKDC DNMBP CDH6

6.45e-05119413120GO:0000902
GeneOntologyBiologicalProcessregulation of T cell differentiation

ERBB2 RC3H1 BRAF SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10

1.00e-042261318GO:0045580
GeneOntologyBiologicalProcesscirculatory system development

ERBB2 XIRP1 PCDHA10 APOB PPP1R13L TYMP RYR1 RYR2 KIF7 GREB1L CFLAR FREM2 DLC1 XIRP2 PIK3CD ALPK3 DCHS1 SMARCA4 ROBO2 SMARCD3 PRKDC ASB2

1.06e-04144213122GO:0072359
GeneOntologyBiologicalProcessmuscle structure development

XIRP1 DDX17 AVPR1A OBSCN RYR1 RYR2 EHD2 CFLAR XIRP2 ALPK3 SMARCA4 SMARCD1 SMARCD2 SMARCD3 PAX5 ASB2

1.10e-0485813116GO:0061061
GeneOntologyBiologicalProcessregulation of actin filament-based process

ADCY10 CARMIL3 PEAK3 RYR2 SPTBN4 WASH3P CORO2B DLC1 BRAF XIRP2 GMFB

1.13e-0443813111GO:0032970
GeneOntologyBiologicalProcessregulation of cellular response to stress

LRRK2 RMI2 CORO2B BRAF SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC TP53BP1 PINK1 NPAS2

1.14e-0459813113GO:0080135
GeneOntologyBiologicalProcessregulation of DNA repair

RMI2 SMARCA4 SMARCD1 SMARCD2 SMARCD3 PRKDC TP53BP1 NPAS2

1.27e-042341318GO:0006282
GeneOntologyBiologicalProcessregulation of leukocyte activation

ERBB2 RC3H1 SH3KBP1 LRRK2 SLC4A1 BRAF LRFN5 SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC TP53BP1

1.36e-0469413114GO:0002694
GeneOntologyBiologicalProcessregulation of G0 to G1 transition

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.44e-04421314GO:0070316
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

CDK20 ERBB2 XIRP1 RC3H1 ROR2 OBSCN PCDHA10 TYMP ITGB4 PRX EHD2 CFLAR PROM1 DLC1 PIK3CD DCHS1 SMARCA4 ROBO2 SMARCD3 PAX2 PRKDC CDC73

1.59e-04148313122GO:0048646
GeneOntologyBiologicalProcessT cell differentiation

ERBB2 RC3H1 BRAF PIK3CD SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC

1.67e-0438213110GO:0030217
GeneOntologyBiologicalProcessregulation of hemopoiesis

ERBB2 RC3H1 ROR2 BRAF SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC CDC73 CNOT4

1.73e-0454013112GO:1903706
GeneOntologyBiologicalProcessG0 to G1 transition

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.73e-04441314GO:0045023
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

ADCY10 ERBB2 KIF1A RC3H1 SH3KBP1 LRRK2 SPART PEAK3 DLC1 PTPRD BRAF PIK3CD ROBO2 FGD5 PAX2 PRKDC DNMBP PINK1

1.85e-04109013118GO:0022603
GeneOntologyBiologicalProcessregulation of cell development

ADCY10 ERBB2 RC3H1 ROR2 LRRK2 SPART TRIM11 PTPRD BRAF SMARCA4 SMARCD1 SMARCD2 ROBO2 SMARCD3 DUSP10 PRKDC CDC73 CNOT4

1.96e-04109513118GO:0060284
GeneOntologyBiologicalProcessmyoblast differentiation

XIRP1 DDX17 SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.34e-041361316GO:0045445
GeneOntologyBiologicalProcessperipheral nervous system myelin formation

ITGB4 PRX

2.38e-0441312GO:0032290
GeneOntologyBiologicalProcesscell junction assembly

LRFN1 DSG1 CARMIL3 ITGB4 CORO2B DLC1 PTPRD LRFN5 ROBO2 PATJ CDH6 MPP7

2.79e-0456913112GO:0034329
GeneOntologyBiologicalProcesspositive regulation of DNA repair

SMARCA4 SMARCD1 SMARCD2 SMARCD3 PRKDC NPAS2

3.07e-041431316GO:0045739
GeneOntologyBiologicalProcessregulation of cell activation

ERBB2 RC3H1 SH3KBP1 LRRK2 SLC4A1 BRAF LRFN5 SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC TP53BP1

3.26e-0475613114GO:0050865
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair

SMARCA4 SMARCD1 SMARCD2 SMARCD3 PRKDC

3.51e-04951315GO:2000781
GeneOntologyBiologicalProcesspositive regulation of leukocyte activation

SH3KBP1 LRRK2 SLC4A1 SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC TP53BP1

3.76e-0442313110GO:0002696
GeneOntologyBiologicalProcesssupramolecular fiber organization

XIRP1 MYO5A CARMIL3 SH3KBP1 OBSCN CCDC57 SPTBN4 CFLAR WASH3P CORO2B DLC1 MAP1S BRAF XIRP2 GMFB HOOK2

3.78e-0495713116GO:0097435
GeneOntologyBiologicalProcesspositive regulation of myoblast differentiation

SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.84e-04541314GO:0045663
GeneOntologyBiologicalProcessparamesonephric duct development

GREB1L PAX2

3.95e-0451312GO:0061205
GeneOntologyBiologicalProcessactin filament organization

XIRP1 MYO5A CARMIL3 SH3KBP1 SPTBN4 WASH3P CORO2B DLC1 BRAF XIRP2 GMFB

4.10e-0450913111GO:0007015
GeneOntologyBiologicalProcessregulation of leukocyte differentiation

ERBB2 RC3H1 ROR2 BRAF SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC

4.20e-0442913110GO:1902105
GeneOntologyBiologicalProcesssynapse organization

ERBB2 LRFN1 KIF1A MYO5A CARMIL3 ROR2 LRRK2 STAU1 SPTBN4 PTPRD LRFN5 ROBO2 CDH6

4.26e-0468513113GO:0050808
GeneOntologyBiologicalProcessregulation of lymphocyte activation

ERBB2 RC3H1 SH3KBP1 SLC4A1 BRAF SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC TP53BP1

5.51e-0461413112GO:0051249
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

PCDHA10 PPP1R13L RYR2 SMARCA4 ROBO2 SMARCD3

5.77e-041611316GO:0003206
GeneOntologyBiologicalProcessregulation of kidney size

LRRK2 PAX2

5.91e-0461312GO:0035564
GeneOntologyBiologicalProcessskeletal muscle atrophy

CFLAR ASB2

5.91e-0461312GO:0014732
GeneOntologyBiologicalProcesspositive regulation of lymphocyte differentiation

SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC

5.96e-041621316GO:0045621
GeneOntologyBiologicalProcesspositive regulation of cell activation

SH3KBP1 LRRK2 SLC4A1 SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC TP53BP1

5.98e-0444913110GO:0050867
GeneOntologyBiologicalProcesslymphocyte differentiation

ERBB2 RC3H1 BRAF PIK3CD SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC PAX5

6.40e-0453713111GO:0030098
GeneOntologyBiologicalProcessregulation of actin filament organization

CARMIL3 SPTBN4 WASH3P CORO2B DLC1 BRAF XIRP2 GMFB

6.73e-043001318GO:0110053
GeneOntologyBiologicalProcessregulation of sister chromatid segregation

RMI2 SMARCA4 SMARCD1 SMARCD2 SMARCD3

7.16e-041111315GO:0033045
GeneOntologyBiologicalProcesshemopoiesis

ERBB2 RC3H1 ROR2 ADAR SLC4A1 CFLAR BRAF PIK3CD SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC PAX5 CDC73 CNOT4 PINK1

7.32e-04122313118GO:0030097
GeneOntologyBiologicalProcessnegative regulation of reactive oxygen species metabolic process

ADCY10 CFLAR PAX2 PINK1

7.35e-04641314GO:2000378
GeneOntologyBiologicalProcesstransmission of nerve impulse

OTOA AVPR1A TYMP PRX SPTBN4

7.46e-041121315GO:0019226
GeneOntologyBiologicalProcessregulation of actin cytoskeleton organization

CARMIL3 PEAK3 SPTBN4 WASH3P CORO2B DLC1 BRAF XIRP2 GMFB

7.87e-043841319GO:0032956
GeneOntologyBiologicalProcessmononuclear cell differentiation

ERBB2 RC3H1 ROR2 BRAF PIK3CD SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC PAX5

7.92e-0464013112GO:1903131
GeneOntologyBiologicalProcesspositive regulation of lymphocyte activation

SH3KBP1 SLC4A1 SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC TP53BP1

8.01e-043851319GO:0051251
GeneOntologyBiologicalProcessprotein processing involved in protein targeting to mitochondrion

PMPCB LRRK2

8.23e-0471312GO:0006627
GeneOntologyBiologicalProcesspositive regulation of epithelial cell differentiation involved in kidney development

PROM1 PAX2

8.23e-0471312GO:2000698
GeneOntologyBiologicalProcessregulation of synaptic vesicle transport

LRRK2 PINK1

8.23e-0471312GO:1902803
GeneOntologyBiologicalProcesspositive regulation of immune system process

RC3H1 ROR2 SH3KBP1 LRRK2 SLC4A1 TRIM11 NLRP10 BRAF PIK3CD LRCH4 SMARCA4 SMARCD1 SMARCD2 SMARCD3 LRRC14 DUSP10 PRKDC TP53BP1

8.74e-04124213118GO:0002684
GeneOntologyBiologicalProcessorganelle assembly

XIRP1 LRFN1 CFAP73 RC3H1 LRRK2 OBSCN CCDC57 HPS3 EHD2 CFLAR WASH3P PTPRD SYNE2 PRKDC ASB2 DNMBP PINK1

8.81e-04113813117GO:0070925
GeneOntologyBiologicalProcesspositive regulation of hemopoiesis

ROR2 SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC

9.13e-042421317GO:1903708
GeneOntologyBiologicalProcesspositive regulation of leukocyte differentiation

ROR2 SMARCA4 SMARCD1 SMARCD2 SMARCD3 DUSP10 PRKDC

9.13e-042421317GO:1902107
GeneOntologyBiologicalProcessregulation of Arp2/3 complex-mediated actin nucleation

CARMIL3 WASH3P GMFB

9.88e-04311313GO:0034315
GeneOntologyCellularComponentcytoplasmic side of membrane

DSG1 LRRK2 RYR1 RYR2 SLC4A1 ITPR3 ESYT3 AP2M1 NLRP10

2.27e-052301389GO:0098562
GeneOntologyCellularComponentanchoring junction

XIRP1 DSG1 SH3KBP1 OBSCN PCDHA10 PEAK3 PLEKHG5 ITGB4 PRX SLC4A1 SPTBN4 CORO2B DLC1 XIRP2 SYNE2 PATJ DNMBP CDH6 MPP7

2.31e-0597613819GO:0070161
GeneOntologyCellularComponentSWI/SNF complex

SMARCA4 SMARCD1 SMARCD2 SMARCD3

4.36e-05301384GO:0016514
GeneOntologyCellularComponentZ disc

OBSCN RYR1 RYR2 SLC4A1 XIRP2 SYNE2 ASB2

6.56e-051511387GO:0030018
GeneOntologyCellularComponentnpBAF complex

SMARCA4 SMARCD1 SMARCD3

9.72e-05141383GO:0071564
GeneOntologyCellularComponentbrahma complex

SMARCD1 SMARCD2 SMARCD3

9.72e-05141383GO:0035060
GeneOntologyCellularComponentI band

OBSCN RYR1 RYR2 SLC4A1 XIRP2 SYNE2 ASB2

1.19e-041661387GO:0031674
GeneOntologyCellularComponentRSC-type complex

SMARCA4 SMARCD1 SMARCD2

1.21e-04151383GO:0016586
GeneOntologyCellularComponentactomyosin

XIRP1 MYO5A CORO2B DLC1 XIRP2 ASB2

1.27e-041171386GO:0042641
GeneOntologyCellularComponentnBAF complex

SMARCA4 SMARCD1 SMARCD3

1.48e-04161383GO:0071565
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

DSG1 RYR1 RYR2 SLC4A1 ESYT3 AP2M1 NLRP10

2.32e-041851387GO:0009898
GeneOntologyCellularComponentsmooth endoplasmic reticulum

MYO5A APOB RYR1 RYR2

2.39e-04461384GO:0005790
GeneOntologyCellularComponentcell-cell contact zone

XIRP1 OBSCN PCDHA10 SLC4A1 SPTBN4

4.00e-04941385GO:0044291
GeneOntologyCellularComponentcell-cell junction

XIRP1 DSG1 SH3KBP1 OBSCN PCDHA10 PLEKHG5 SLC4A1 SPTBN4 PATJ DNMBP CDH6 MPP7

5.59e-0459113812GO:0005911
GeneOntologyCellularComponentcontractile actin filament bundle

XIRP1 CORO2B DLC1 XIRP2 ASB2

7.23e-041071385GO:0097517
GeneOntologyCellularComponentstress fiber

XIRP1 CORO2B DLC1 XIRP2 ASB2

7.23e-041071385GO:0001725
GeneOntologyCellularComponentpresynapse

ERBB2 LRFN1 SYN3 KIF1A MYO5A LRRK2 PLEKHG5 ITPR3 AP2M1 PTPRD KCNA6 BRAF DNMBP ATP2B3 SLC30A10

7.71e-0488613815GO:0098793
GeneOntologyCellularComponentextrinsic component of membrane

SYN3 RYR1 RYR2 AP2M1 PIK3CD DCHS1 CDH6

8.53e-042301387GO:0019898
GeneOntologyCellularComponentglutamatergic synapse

SYN3 MYO5A CARMIL3 ROR2 LRRK2 ITGB4 STAU1 AP2M1 PTPRD BRAF LRFN5 ROBO2 ATP2B3 CDH6

1.03e-0381713814GO:0098978
GeneOntologyCellularComponentintercalated disc

XIRP1 OBSCN SLC4A1 SPTBN4

1.07e-03681384GO:0014704
GeneOntologyCellularComponentactin filament bundle

XIRP1 CORO2B DLC1 XIRP2 ASB2

1.12e-031181385GO:0032432
GeneOntologyCellularComponentsarcomere

OBSCN RYR1 RYR2 SLC4A1 XIRP2 SYNE2 ASB2

1.35e-032491387GO:0030017
GeneOntologyCellularComponentcell leading edge

ERBB2 MYO5A CARMIL3 PLEKHG5 ITGB4 WASH3P DLC1 SYNE2 ROBO2 FGD5

1.81e-0350013810GO:0031252
GeneOntologyCellularComponentbBAF complex

SMARCA4 SMARCD2

1.88e-03101382GO:0140092
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

RYR1 RYR2

1.88e-03101382GO:0014701
GeneOntologyCellularComponentsupramolecular fiber

DNAH10 KIF1A MYO5A ROR2 OBSCN CCDC57 RYR1 RYR2 SLC4A1 KIF7 SPTBN4 DLC1 MAP1S XIRP2 SYNE2 HOOK2 ASB2

1.99e-03117913817GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

DNAH10 KIF1A MYO5A ROR2 OBSCN CCDC57 RYR1 RYR2 SLC4A1 KIF7 SPTBN4 DLC1 MAP1S XIRP2 SYNE2 HOOK2 ASB2

2.14e-03118713817GO:0099081
GeneOntologyCellularComponentextrinsic component of plasma membrane

RYR1 RYR2 AP2M1 DCHS1 CDH6

2.17e-031371385GO:0019897
GeneOntologyCellularComponentmyofibril

OBSCN RYR1 RYR2 SLC4A1 XIRP2 SYNE2 ASB2

2.28e-032731387GO:0030016
GeneOntologyCellularComponentnuclear outer membrane

ITPR3 GUCY2D SYNE2

2.33e-03401383GO:0005640
GeneOntologyCellularComponentactin-based cell projection

ERBB2 MYO5A LRRK2 PROM1 WASH3P SYNE2 SYTL1

2.52e-032781387GO:0098858
GeneOntologyCellularComponentorganelle outer membrane

LRRK2 AGPAT4 SPART ITPR3 GUCY2D SYNE2 PINK1

2.57e-032791387GO:0031968
GeneOntologyCellularComponentouter membrane

LRRK2 AGPAT4 SPART ITPR3 GUCY2D SYNE2 PINK1

2.67e-032811387GO:0019867
GeneOntologyCellularComponentsarcoplasmic reticulum

RYR1 RYR2 ITPR3 SYNE2

2.76e-03881384GO:0016529
GeneOntologyCellularComponentcontractile muscle fiber

OBSCN RYR1 RYR2 SLC4A1 XIRP2 SYNE2 ASB2

3.18e-032901387GO:0043292
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 RYR2 SYNE2

3.26e-03451383GO:0033017
GeneOntologyCellularComponentcell cortex

ITGB4 RYR1 SLC4A1 SPTBN4 WASH3P DLC1 GMFB MPP7

3.28e-033711388GO:0005938
GeneOntologyCellularComponentGBAF complex

SMARCA4 SMARCD1

3.74e-03141382GO:0140288
GeneOntologyCellularComponentSWI/SNF superfamily-type complex

SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.78e-03961384GO:0070603
GeneOntologyCellularComponentendocytic vesicle

AVPR1A ROR2 SH3KBP1 APOB ECPAS PLEKHG5 EHD2 AP2M1

4.04e-033841388GO:0030139
GeneOntologyCellularComponentmicrotubule associated complex

DNAH10 KIF1A KIF7 STAU1 MAP1S

4.34e-031611385GO:0005875
MousePhenoabnormal intercalated disk morphology

XIRP1 PPP1R13L XIRP2 ALPK3

1.22e-05181154MP:0006267
MousePhenopigmentation phenotype

CDK20 MYO5A LRRK2 BMS1 OAT ECPAS GTF2IRD1 HPS3 PROM1 FREM2 CORO2B FBXO10 BRAF RBM6 PAX2 PRKDC ATP2B3

1.31e-0562411517MP:0001186
MousePhenoabnormal muscle contractility

BIRC8 XIRP1 AVPR1A OBSCN PPP1R13L RYR1 RYR2 SLC4A1 SPTBN4 FBXO10 BRAF ALPK3 SMARCD3

3.89e-0541811513MP:0005620
MousePhenoabnormal myocardial fiber currents

XIRP1 RYR2 XIRP2

4.39e-0591153MP:0020345
DomainSWIB_domain

SMARCD1 SMARCD2 SMARCD3

3.69e-0731353IPR019835
DomainSWIB

SMARCD1 SMARCD2 SMARCD3

3.69e-0731353SM00151
DomainSWIB

SMARCD1 SMARCD2 SMARCD3

3.65e-0651353PF02201
DomainRIH_assoc-dom

RYR1 RYR2 ITPR3

7.27e-0661353IPR013662
DomainIns145_P3_rec

RYR1 RYR2 ITPR3

7.27e-0661353PF08709
Domain-

SMARCD1 SMARCD2 SMARCD3

7.27e-06613531.10.245.10
DomainRIH_assoc

RYR1 RYR2 ITPR3

7.27e-0661353PF08454
DomainRIH_dom

RYR1 RYR2 ITPR3

7.27e-0661353IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2 ITPR3

7.27e-0661353IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2 ITPR3

7.27e-0661353IPR015925
Domain-

RYR1 RYR2 ITPR3

7.27e-06613531.25.10.30
DomainRYDR_ITPR

RYR1 RYR2 ITPR3

7.27e-0661353PF01365
DomainSWIB_MDM2_domain

SMARCD1 SMARCD2 SMARCD3

7.27e-0661353IPR003121
DomainKinase-like_dom

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN PEAK3 BRAF PIK3CD PDIK1L GUCY2D ALPK3 PRKDC PINK1

3.88e-0554213514IPR011009
DomainMIR

RYR1 RYR2 ITPR3

4.27e-05101353PF02815
DomainMIR_motif

RYR1 RYR2 ITPR3

4.27e-05101353IPR016093
DomainMIR

RYR1 RYR2 ITPR3

4.27e-05101353PS50919
DomainMIR

RYR1 RYR2 ITPR3

4.27e-05101353SM00472
DomainActin-binding_Xin_repeat

XIRP1 XIRP2

5.19e-0521352IPR012510
DomainXIRP1/XIRP2

XIRP1 XIRP2

5.19e-0521352IPR030072
DomainXIN

XIRP1 XIRP2

5.19e-0521352PS51389
DomainXin

XIRP1 XIRP2

5.19e-0521352PF08043
DomainDUF1220

NBPF15 NBPF9 NBPF14

5.84e-05111353PF06758
DomainNBPF_dom

NBPF15 NBPF9 NBPF14

5.84e-05111353IPR010630
DomainNBPF

NBPF15 NBPF9 NBPF14

5.84e-05111353PS51316
DomainPax2_C

PAX2 PAX5

1.55e-0431352IPR022130
DomainPax2_C

PAX2 PAX5

1.55e-0431352PF12403
DomainRyanodine_rcpt

RYR1 RYR2

1.55e-0431352IPR003032
DomainRyanrecept_TM4-6

RYR1 RYR2

1.55e-0431352IPR009460
DomainRyR

RYR1 RYR2

1.55e-0431352PF02026
DomainRR_TM4-6

RYR1 RYR2

1.55e-0431352PF06459
DomainRyan_recept

RYR1 RYR2

1.55e-0431352IPR013333
DomainP-loop_NTPase

ADCY10 DDX17 DNAH10 KIF1A MYO5A TOR2A LRRK2 BMS1 PSMC2 KIF7 EHD2 NLRP10 SMARCA4 DDX53 MPP7 NLRP8

4.17e-0484813516IPR027417
DomainIg_I-set

LRFN1 ROR2 OBSCN PTPRD LRFN5 ALPK3 ROBO2

4.67e-041901357IPR013098
DomainI-set

LRFN1 ROR2 OBSCN PTPRD LRFN5 ALPK3 ROBO2

4.67e-041901357PF07679
DomainFN3

LRFN1 COL20A1 OBSCN ITGB4 PTPRD LRFN5 ROBO2

6.15e-041991357PS50853
DomainARM-type_fold

CAND2 LRRK2 USP24 APOB ECPAS TRIP12 NOP9 PIK3CD PRKDC

8.11e-043391359IPR016024
DomainFN3_dom

LRFN1 COL20A1 OBSCN ITGB4 PTPRD LRFN5 ROBO2

8.22e-042091357IPR003961
Domainfn3

LRFN1 COL20A1 OBSCN ITGB4 PTPRD ROBO2

1.16e-031621356PF00041
DomainCalx_beta

ITGB4 FREM2

1.41e-0381352SM00237
DomainRhoGEF

OBSCN PLEKHG5 FGD5 DNMBP

1.49e-03681354SM00325
DomainCA

DSG1 PCDHA10 FREM2 DCHS1 CDH6

1.49e-031151355SM00112
DomainIGc2

LRFN1 ROR2 OBSCN PTPRD LRFN5 ALPK3 ROBO2

1.62e-032351357SM00408
DomainIg_sub2

LRFN1 ROR2 OBSCN PTPRD LRFN5 ALPK3 ROBO2

1.62e-032351357IPR003598
DomainRhoGEF

OBSCN PLEKHG5 FGD5 DNMBP

1.66e-03701354PF00621
DomainDH_2

OBSCN PLEKHG5 FGD5 DNMBP

1.66e-03701354PS50010
DomainCadherin

DSG1 PCDHA10 FREM2 DCHS1 CDH6

1.67e-031181355IPR002126
Domain-

OBSCN PLEKHG5 FGD5 DNMBP

1.74e-037113541.20.900.10
DomainDH-domain

OBSCN PLEKHG5 FGD5 DNMBP

1.74e-03711354IPR000219
DomainCalx_beta

ITGB4 FREM2

1.81e-0391352IPR003644
DomainPAX

PAX2 PAX5

1.81e-0391352SM00351
DomainPAIRED_2

PAX2 PAX5

1.81e-0391352PS51057
DomainPAIRED_1

PAX2 PAX5

1.81e-0391352PS00034
DomainPaired_dom

PAX2 PAX5

1.81e-0391352IPR001523
DomainPAX

PAX2 PAX5

1.81e-0391352PF00292
DomainCalx-beta

ITGB4 FREM2

1.81e-0391352PF03160
DomainDUF1220

NBPF15 NBPF9

1.81e-0391352SM01148
DomainFN3

LRFN1 COL20A1 OBSCN ITGB4 PTPRD ROBO2

2.28e-031851356SM00060
DomainL_dom-like

ERBB2 LRFN1 CARMIL3 LRRK2 LRFN5 LRCH4 LRRC14 NLRP8

2.68e-033281358IPR032675
DomainProt_kinase_dom

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN BRAF PDIK1L GUCY2D PINK1

2.95e-0348913510IPR000719
Domain-

ADCY10 DDX17 DNAH10 TOR2A LRRK2 BMS1 PSMC2 EHD2 NLRP10 SMARCA4 DDX53 MPP7 NLRP8

2.95e-03746135133.40.50.300
DomainPROTEIN_KINASE_DOM

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN BRAF PDIK1L GUCY2D PINK1

3.12e-0349313510PS50011
DomainLeu-rich_rpt

LRFN1 CARMIL3 LRRK2 LRFN5 LRCH4 LRRC14 NLRP8

3.59e-032711357IPR001611
DomainL27

PATJ MPP7

3.84e-03131352SM00569
DomainL27

PATJ MPP7

3.84e-03131352PS51022
DomainL27_dom

PATJ MPP7

3.84e-03131352IPR004172
DomainHEAT

CAND2 ECPAS PRKDC

5.04e-03481353PF02985
DomainPI3/4_kinase_CS

PIK3CD PRKDC

5.12e-03151352IPR018936
Domain-

CAND2 LRRK2 ECPAS TRIP12 NOP9 PRKDC

5.56e-0322213561.25.10.10
Domain-

PIK3CD PRKDC

5.82e-031613521.10.1070.11
DomainPI3Kc

PIK3CD PRKDC

5.82e-03161352SM00146
DomainPROTEIN_KINASE_ATP

CDK20 ERBB2 CDKL2 ROR2 LRRK2 OBSCN BRAF PDIK1L PINK1

6.19e-034591359PS00107
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

RING1 SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.84e-06341005MM15531
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

RING1 SMARCA4 SMARCD1 SMARCD2 SMARCD3

5.91e-06371005M27797
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

MYO5A SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.12e-05421005M48237
PathwayWP_KLEEFSTRA_SYNDROME

SMARCA4 SMARCD1 SMARCD2 SMARCD3

4.94e-05291004M48076
PathwayWP_TUMOR_SUPPRESSOR_ACTIVITY_OF_SMARCB1

SMARCA4 SMARCD1 SMARCD2 SMARCD3

6.47e-05311004M39522
PathwayKEGG_MEDICUS_REFERENCE_ADRB3_UCP1_SIGNALING_PATHWAY

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.05e-04351004M47969
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX1

PSMC2 RING1 SMARCA4 SMARCD1 SMARCD2 SMARCD3 PAX5

1.06e-041531007MM15522
PathwayREACTOME_RMTS_METHYLATE_HISTONE_ARGININES

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.79e-04401004MM14936
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR1 RYR2 ITPR3

3.09e-04191003M47760
Pubmed

A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.

NBPF20 NBPF19 NBPF15 NBPF9 NBPF10 NBPF14

2.15e-1021142616079250
Pubmed

Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm.

SMARCA4 SMARCD1 SMARCD2 SMARCD3 PAX2

8.18e-1012142533723076
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

DDX17 DNAH10 AVPR1A BMS1 EFCAB2 PSMC2 HPS3 VPS13D SYNE2 SYTL1 PATJ GOLGA3

1.78e-092771421230745168
Pubmed

Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

9.23e-097142428369036
Pubmed

Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

5.49e-0810142434716243
Pubmed

Expression analysis of Baf60c during heart regeneration in axolotls and neonatal mice.

SMARCD1 SMARCD2 SMARCD3

6.66e-083142327125315
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

KIF1A MYO5A BMS1 USP24 PSMC2 OAT ECPAS TRIP12 STAU1 ITPR3 SYNE2 RBM6 SMARCA4 PRKDC TP53BP1

8.24e-086531421522586326
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

SH3KBP1 AGPAT4 PCDHA10 GTF2IRD1 PRX RYR1 PIK3CD GUCY2D SMARCD1 SMARCD2 SMARCD3

1.22e-073291421117474147
Pubmed

Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.85e-0713142411726552
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

DDX17 CAND2 PMPCB PSMC2 ADAR TRIP12 STAU1 NOP9 AP2M1 MAP1S SMARCA4 SMARCD2 PRKDC CDC73 TP53BP1

2.16e-077041421529955894
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

TRIP12 NBPF20 PRX NBPF19 TNRC18 MAP1S XIRP2 NBPF9 CCDC87 PATJ NBPF14 SAP130

2.24e-074301421235044719
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

MYO5A DSG1 SH3KBP1 ECPAS PPP1R13L DUS3L ADAR PLEKHG5 ZNF24 AP2M1 DLC1 LRCH4 RBM6 SMARCA4 FGD5 PATJ DNMBP

2.26e-079161421732203420
Pubmed

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.58e-071414248895581
Pubmed

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.51e-0715142411175787
Pubmed

Regulation of dendritic development by neuron-specific chromatin remodeling complexes.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.51e-0715142417920018
Pubmed

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.51e-0715142411263494
Pubmed

Human transcription factor protein interaction networks.

DNAH10 MYO5A RC3H1 SH3KBP1 BMS1 PSMC2 UBN2 KIF7 STAU1 RING1 ZNF24 AP2M1 SYNE2 RBM6 SMARCA4 SMARCD1 SMARCD2 SMARCD3 PAX2 SAP130 TP53BP1

3.78e-0714291422135140242
Pubmed

Targeting USP9X-AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

4.67e-0716142435390516
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

CAND2 KIF1A PMPCB GPX8 BMS1 PSMC2 OAT ECPAS KIF7 ITPR3 AP2M1 PTPRD DUSP10 PRKDC HOOK2 CDC73 MPP7

5.30e-079741421728675297
Pubmed

Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome.

SMARCD1 SMARCD2 SMARCD3

6.62e-07514239693044
Pubmed

BAF complexes facilitate decatenation of DNA by topoisomerase IIα.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

7.80e-0718142423698369
Pubmed

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

9.84e-0719142412110891
Pubmed

Mammalian SWI/SNF complexes facilitate DNA double-strand break repair by promoting gamma-H2AX induction.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

9.84e-0719142416932743
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR2 ITPR3

1.32e-066142325966694
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR2 ITPR3

1.32e-066142320519450
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR2 ITPR3

1.32e-066142323463619
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR2 ITPR3

1.32e-066142316844763
Pubmed

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.

SMARCA4 SMARCD1 SMARCD2 SMARCD3 TP53BP1

1.74e-0649142527352031
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DDX17 MYO5A BMS1 ECPAS TRIP12 ITGB4 ITPR3 PRKDC

1.94e-06202142833005030
Pubmed

A protein interaction landscape of breast cancer.

ERBB2 MYO5A USP28 ECPAS STAU1 ITPR3 AP2M1 LRCH4 SMARCA4 SMARCD1 SMARCD2 SMARCD3 CDC73

2.21e-066341421334591612
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.22e-0623142430962207
Pubmed

Genomic variants in an inbred mouse model predict mania-like behaviors.

OBSCN HPS3 SMARCA4 NPAS2

2.22e-0623142429768498
Pubmed

Diversity and specialization of mammalian SWI/SNF complexes.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.22e-062314248804307
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR2 ITPR3

2.30e-067142311860456
Pubmed

SWI/SNF chromatin remodeling and cancer.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.66e-0624142411790558
Pubmed

The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.66e-0624142412215535
Pubmed

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.66e-0624142410078207
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR2 ITPR3

3.68e-068142319033399
Pubmed

Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

3.71e-0626142410778858
Pubmed

Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

4.35e-0627142429374058
Pubmed

REST repression of neuronal genes requires components of the hSWI.SNF complex.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

5.05e-0628142412192000
Pubmed

A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.

SMARCA4 SMARCD1 SMARCD2 SMARCD3 CDC73

5.23e-0661142520305087
Pubmed

Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

5.84e-0629142415525990
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DDX17 DNAH10 KIF1A DSG1 PMPCB BMS1 OAT APOB ECPAS ADAR STAU1 NOP9 AP2M1 SMARCA4 FGD5 PRKDC CDC73 ATP2B3 NPAS2

5.85e-0614251421930948266
Pubmed

Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

6.72e-0630142431043422
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

USP28 TRIP12 ITGB4 ITPR3 PTPRD SYNE2 SMARCD1 GMFB PRKDC

7.60e-06322142926514267
Pubmed

Evolutionary history and genome organization of DUF1220 protein domains.

NBPF15 NBPF9 NBPF14

7.83e-0610142322973535
Pubmed

Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1.

DDX17 RING1 ZNF24 SMARCA4 SMARCD2 PRKDC

8.55e-06116142621549307
Pubmed

Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells.

PMPCB ZNF24 SMARCA4 SMARCD1 SMARCD2 PRKDC TP53BP1

9.09e-06178142727637333
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ERBB2 KIF1A MYO5A ROR2 OBSCN ECPAS GTF2IRD1 UBN2 CCDC57 HPS3 SPTBN4 EXD3 TNRC18 RBM6 HOOK2 SYTL1 PATJ SAP130 NPAS2

1.09e-0514891421928611215
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

DDX17 RMI2 ECPAS UBN2 ADAR STAU1 ZNF24 TNRC18 AP2M1 SMARCA4 SMARCD1 SMARCD2 PRKDC CDC73 SAP130 TP53BP1

1.21e-0511031421634189442
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERBB2 LRFN1 OBSCN REV3L GTF2IRD1 PLEKHG5 ITGB4 RYR1 ITPR3 TNRC18 MAP1S PIK3CD PAX2 LRRC14 PRKDC DNMBP

1.24e-0511051421635748872
Pubmed

The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.26e-0535142432504627
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

USP24 REV3L RYR1 RYR2 KIF7 ITPR3 NBPF15 EXD3 SYNE2 SMARCD1 FGD5 ATP2B3

1.31e-056381421231182584
Pubmed

Role of Wnt5a-Ror2 signaling in morphogenesis of the metanephric mesenchyme during ureteric budding.

ROR2 ROBO2 PAX2

1.43e-0512142324891614
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

DDX17 MYO5A BMS1 ADAR TRIP12 STAU1 NOP9 AP2M1 RBM6 SMARCA4 PRKDC CDC73 SAP130

1.52e-057591421335915203
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

USP28 UBN2 TNRC18 SMARCA4 SMARCD1 SMARCD2 CDC73 SAP130

1.54e-05268142833640491
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

DDX17 MYO5A DSG1 PMPCB BMS1 OAT PPP1R13L ADAR TRIP12 ITGB4 STAU1 ITPR3 AP2M1 SMARCA4 SMARCD2 PRKDC PATJ

1.57e-0512571421736526897
Pubmed

Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.

SMARCA4 SMARCD1 SMARCD2 SMARCD3

1.58e-0537142424335282
Pubmed

A knock-in mouse model of N-terminal R420W mutation of cardiac ryanodine receptor exhibits arrhythmogenesis with abnormal calcium dynamics in cardiomyocytes.

RC3H1 RYR2

1.66e-052142225193700
Pubmed

Emergence of Xin demarcates a key innovation in heart evolution.

XIRP1 XIRP2

1.66e-052142218682726
Pubmed

Kinase signaling dysfunction in Parkinson's disease: a reverse genetic approach in Drosophila.

LRRK2 PINK1

1.66e-052142222486164
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

1.66e-052142214722100
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

1.66e-052142226009179
Pubmed

Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells.

RYR2 ITPR3

1.66e-052142218586264
Pubmed

Uncoupling Exercise Bioenergetics From Systemic Metabolic Homeostasis by Conditional Inactivation of Baf60 in Skeletal Muscle.

SMARCD1 SMARCD3

1.66e-052142229092888
Pubmed

CDKL2 Is Associated with HER2 Status and Overall Survival in Gastric Cancer: Comparative Analysis of CDKL2 Protein Expression and Gene Copy Number.

ERBB2 CDKL2

1.66e-052142233178818
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

1.66e-052142215033925
Pubmed

Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.

USP28 BRAF

1.66e-052142229880484
Pubmed

Prevalence and Clinicopathological Characteristics of HER2 and BRAF Mutation in Chinese Patients with Lung Adenocarcinoma.

ERBB2 BRAF

1.66e-052142226102513
Pubmed

Identification of two promoters for human D-amino acid oxidase gene: implication for the differential promoter regulation mediated by PAX5/PAX2.

PAX2 PAX5

1.66e-052142225500505
Pubmed

Regulatory mechanisms and pathophysiological significance of IP3 receptors and ryanodine receptors in drug dependence.

RYR2 ITPR3

1.66e-052142224285081
Pubmed

Structural basis of SALM5-induced PTPδ dimerization for synaptic differentiation.

PTPRD LRFN5

1.66e-052142229348579
Pubmed

Structural basis of trans-synaptic interactions between PTPδ and SALMs for inducing synapse formation.

PTPRD LRFN5

1.66e-052142229348429
Pubmed

The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.

PIK3CD PRKDC

1.66e-052142219596993
Pubmed

Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.

RYR1 RYR2

1.66e-052142225370123
Pubmed

Structure, Expression, and Function of a Novel Intercalated Disc Protein, Xin.

XIRP1 XIRP2

1.66e-052142216708114
Pubmed

Distribution of PINK1 and LRRK2 in rat and mouse brain.

LRRK2 PINK1

1.66e-052142216771836
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

1.66e-052142217259277
Pubmed

DNA damage response in CD133 + stem/progenitor cells from umbilical cord blood: low level of endogenous foci and high recruitment of 53BP1.

PROM1 TP53BP1

1.66e-052142223206244
Pubmed

Beta 4 integrin amplifies ErbB2 signaling to promote mammary tumorigenesis.

ERBB2 ITGB4

1.66e-052142216901783
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

1.66e-052142232899693
Pubmed

LRRK2 Expression Is Deregulated in Fibroblasts and Neurons from Parkinson Patients with Mutations in PINK1.

LRRK2 PINK1

1.66e-052142227975167
Pubmed

Diagnostic utility of PAX2 and PAX5 in distinguishing non-small cell lung cancer from small cell lung cancer.

PAX2 PAX5

1.66e-052142226823795
Pubmed

Control of cell proliferation by memories of mitosis.

USP28 TP53BP1

1.66e-052142238547292
Pubmed

ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay.

ADAR STAU1

1.66e-052142228436945
Pubmed

Function of erbB receptors and DNA-PKcs on phosphorylation of cytoplasmic and nuclear Akt at S473 induced by erbB1 ligand and ionizing radiation.

ERBB2 PRKDC

1.66e-052142221723633
Pubmed

Genetic Heterogeneity of HER2 Amplification and Telomere Shortening in Papillary Thyroid Carcinoma.

ERBB2 BRAF

1.66e-052142227775641
Pubmed

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.

RYR1 RYR2

1.66e-052142230542613
Pubmed

Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.

PAX2 PAX5

1.66e-052142210662641
Pubmed

Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.

RYR1 RYR2

1.66e-052142215280431
Pubmed

Expression of the ryanodine receptor isoforms in immune cells.

RYR1 RYR2

1.66e-052142211673493
Pubmed

B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.

RYR1 RYR2

1.66e-052142211673462
Pubmed

Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease.

LRRK2 PINK1

1.66e-052142222764206
Pubmed

Common allosteric mechanisms between ryanodine and inositol-1,4,5-trisphosphate receptors.

RYR1 ITPR3

1.66e-052142221150295
Pubmed

The Xin repeat-containing protein, mXinβ, initiates the maturation of the intercalated discs during postnatal heart development.

XIRP1 XIRP2

1.66e-052142223261932
Pubmed

Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.

RYR1 RYR2

1.66e-052142218618700
Pubmed

Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.

DDX17 DSG1 PMPCB SPART ADAR STAU1 SMARCD3 PRKDC CDC73

1.72e-05357142937059091
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

RYR1 RYR2 ITPR3 ATP2B3

1.76e-0538142430786075
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

GPX8 USP28 RMI2 PPP1R13L GTF2IRD1 SMARCD1 SMARCD2 SMARCD3 SAP130 TP53BP1

1.83e-054531421029656893
InteractionERG interactions

MYO5A ADAR TRIP12 RING1 PTPRD SMARCA4 SMARCD1 SMARCD2 SMARCD3 PRKDC

3.45e-0622313910int:ERG
InteractionPSMD14 interactions

DDX17 DNAH10 AVPR1A BMS1 EFCAB2 PSMC2 APOB ECPAS HPS3 VPS13D SYNE2 SYTL1 PATJ GOLGA3 TP53BP1

3.73e-0652713915int:PSMD14
InteractionSLX4 interactions

DDX17 DSG1 PMPCB SPART REV3L UBN2 ADAR STAU1 AP2M1 RBM6 SMARCA4 SMARCD3 PRKDC CDC73 TP53BP1

9.95e-0657213915int:SLX4
InteractionOPALIN interactions

ERBB2 CAND2 AGPAT4 ECPAS PTPRD PRKDC ATP2B3 RUSF1 MPP7

1.50e-052091399int:OPALIN
InteractionETS1 interactions

UBN2 SPTBN4 SMARCA4 SMARCD1 SMARCD2 SMARCD3 PAX5

2.09e-051211397int:ETS1
InteractionMDC1 interactions

USP28 SH3KBP1 ADAR TRIP12 STAU1 BRAF SMARCA4 SMARCD1 SMARCD2 SMARCD3 PRKDC TP53BP1

3.07e-0541413912int:MDC1
GeneFamilyNeuroblastoma breakpoint family

NBPF20 NBPF19 NBPF15 NBPF9 NBPF10 NBPF14

1.68e-0923956662
GeneFamilyFibronectin type III domain containing

LRFN1 COL20A1 OBSCN ITGB4 PTPRD LRFN5 ROBO2

2.14e-05160957555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

LRFN1 ROR2 OBSCN PTPRD LRFN5 ALPK3 ROBO2

2.23e-05161957593
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

8.17e-053952287
GeneFamilyPaired boxes

PAX2 PAX5

9.60e-049952675
GeneFamilyParkinson disease associated genes

LRRK2 PINK1

3.12e-0316952672
GeneFamilyWiskott-Aldrich Syndrome protein family

WASH3P WASH2P

3.12e-031695214
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 DLC1 PTPRD PATJ MPP7

1.19e-081921429fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA DNAH10 OBSCN APOB RYR2 FREM2 PTPRD XIRP2

1.41e-0718414282cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA DNAH10 OBSCN APOB RYR2 FREM2 PTPRD XIRP2

1.41e-071841428ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOA DNAH10 OBSCN APOB RYR2 FREM2 PTPRD XIRP2

1.41e-0718414282b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

CAND2 ROR2 AGPAT4 PLEKHG5 ITGB4 EHD2 PIK3CD SMARCD3

2.20e-0719514285562665dd3beb70e2358aa32611a337bef5731c1
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A AVPR1A CFAP73 APOBEC4 RYR1 SPTBN4 ATP2B3

1.71e-061781427a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A AVPR1A CFAP73 APOBEC4 RYR1 SPTBN4 ATP2B3

1.71e-0617814271bddbc083c36657bd6910f7466126ab325e88176
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LRRK2 AGPAT4 PPP1R13L PRX TNRC18 SMARCD3 PRKDC

2.21e-061851427daea170d827226dda6750bf1838ffd82f070c4d4
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 DLC1 MPP7

2.55e-061891427dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

XIRP1 OBSCN GTF2IRD1 RYR2 XIRP2 ALPK3 HOOK2

2.55e-0618914270a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 ESYT3 FREM2 DLC1 PTPRD PATJ MPP7

2.73e-06191142734cc997e4e5c727495f321e6807a84aa124da486
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDKL2 LRRK2 FREM2 DLC1 PTPRD PATJ MPP7

2.73e-061911427a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LRRK2 ITPR3 ESYT3 FREM2 DLC1 PATJ MPP7

2.73e-061911427ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RYR2 FREM2 NLRP10 XIRP2 ALPK3 ASB2

2.82e-061921427f6a4e348406a852ace9fb21db8fbdff539217645
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

CDKL2 LRRK2 ITPR3 FREM2 DLC1 PATJ MPP7

2.82e-06192142758c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RYR2 FREM2 NLRP10 XIRP2 ALPK3 ASB2

2.82e-0619214271a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

OBSCN RYR2 GREB1L XIRP2 ALPK3 PATJ NPAS2

2.92e-061931427dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A CDKL2 LRRK2 ITPR3 PROM1 SYNE2 PATJ

3.02e-061941427e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

OBSCN GTF2IRD1 RYR2 GREB1L XIRP2 ALPK3 PATJ

3.13e-06195142775fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A RYR2 LRFN5 FAM124A MAEL ASB2 CDH6

3.24e-0619614279830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

DENND2A ROR2 RYR2 DLC1 PTPRD LRFN5 ROBO2

3.58e-0619914275b9d355795dd03a22f0961dfd143425c367a4654
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C-8|TCGA-Thymus / Sample_Type by Project: Shred V9

CARMIL3 APOBEC4 FGD5 PAX2 DUSP10 PAX5

1.06e-05155142600eef9f93a753a1fe1ab5fd8dae026e7be556cde
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ERBB2 GPX8 OAT ITGB4 EHD2 NPAS2

1.72e-051691426aec97583b23112060437b619cb429dc32f29285f
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

XIRP1 OBSCN RYR2 GREB1L XIRP2 ASB2

1.78e-0517014263f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DENND2A DUS3L RYR1 EXD3 FAM124A HOOK2

1.90e-05172142680b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

USP24 JCHAIN SMARCD1 MAEL LRRC14 PAX5

2.24e-05177142695760841b3f085d38c4926b258a33563d93a2016
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PROM1 LRFN5 SYNE2 PAX2 PATJ CDH6

2.31e-051781426544379f5a6145429762258d426b876bb36c112f5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A CFAP73 APOBEC4 RYR1 LRFN5 ATP2B3

2.38e-051791426a3922476f33d2e4137a12dbda21a1703dff79684
ToppCellControl-Epithelial_cells-AT2|Control / group, cell type (main and fine annotations)

CDKL2 LRRK2 FREM2 DLC1 PTPRD MPP7

2.46e-051801426198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDKL2 LRRK2 GTF2IRD1 PROM1 PAX2 PATJ

2.54e-0518114269d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

XIRP1 OBSCN RYR2 GREB1L XIRP2 ALPK3

2.54e-051811426719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellRV|World / Chamber and Cluster_Paper

OBSCN EFCAB2 CFLAR XIRP2 HOOK2 PATJ

2.54e-051811426bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CDKL2 LRRK2 GTF2IRD1 PROM1 PAX2 PATJ

2.62e-051821426eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A ROR2 REV3L RYR2 ROBO2 NPAS2

2.62e-051821426ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

PROM1 PTPRD SYNE2 PAX2 PATJ CDH6

2.70e-0518314266878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CDKL2 LRRK2 FREM2 DLC1 PATJ MPP7

2.70e-0518314266847c1252d6bb105524f812658112517fd351eab
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

XIRP1 OBSCN RYR2 GREB1L XIRP2 HOOK2

2.78e-051841426ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

OBSCN RYR2 GREB1L XIRP2 ALPK3 ASB2

2.78e-051841426e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

XIRP1 OBSCN RYR2 GREB1L XIRP2 ALPK3

2.87e-051851426549eeb521c3985bff396ea0f202db21822efa51f
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

OBSCN RYR2 GREB1L XIRP2 HOOK2 PATJ

2.87e-0518514266baccb26f999145e51b91d94315bf8d4655bef31
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 GREB1L PROM1 FREM2 PAX2 CDH6

2.96e-0518614265c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MYO5A ESYT3 FREM2 PATJ MPP7 NPAS2

3.05e-051871426db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CDKL2 LRRK2 ITPR3 FREM2 PATJ MPP7

3.05e-0518714265df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR2 RYR2 PROM1 FREM2 ROBO2 ASB2

3.14e-051881426293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

AVPR1A PROM1 ROBO2 FAM124A ASB2 CDH6

3.14e-0518814263004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPX8 EHD2 CORO2B DCHS1 FAM124A FGD5

3.23e-051891426ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

XIRP1 OBSCN GTF2IRD1 RYR2 XIRP2 ALPK3

3.33e-05190142693c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A ROR2 REV3L RYR2 PTPRD NPAS2

3.33e-05190142645df8fee00f8949937863159d7aa042e72748d9b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A CDKL2 LRRK2 PROM1 SYNE2 PAX2

3.43e-051911426d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A ROR2 REV3L RYR2 LRFN5 ROBO2

3.43e-05191142608720998aa55131d7377c4c67c4c935865bd7d79
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

CDKL2 LRRK2 ESYT3 FREM2 PATJ MPP7

3.43e-051911426276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 OBSCN RYR2 XIRP2 ALPK3 ASB2

3.43e-051911426c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 OBSCN RYR2 XIRP2 ALPK3 ASB2

3.43e-05191142697fb4232417a39801e87725755fd16a57c250209
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR2 RYR2 PROM1 ROBO2 ASB2 CDH6

3.43e-051911426b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 OBSCN RYR2 XIRP2 ALPK3 ASB2

3.43e-05191142664070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 OBSCN RYR2 XIRP2 ALPK3 ASB2

3.43e-051911426715f5b449b8e075959c05a5b38389df319663164
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A SYN3 ROR2 RYR2 LRFN5 ROBO2

3.43e-0519114266688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RYR2 NLRP10 XIRP2 ALPK3 ASB2

3.53e-0519214260bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RYR2 NLRP10 XIRP2 ALPK3 ASB2

3.53e-051921426d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellControl-Fibroblasts-Vascular_smooth_muscle|Control / group, cell type (main and fine annotations)

DENND2A SYN3 PRX RYR2 ROBO2 CDH6

3.64e-05193142660e44aac8be0430ad35e20eb98b1b700d76a0427
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DENND2A SYN3 ROR2 RYR2 DLC1 ROBO2

3.64e-051931426b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

CDKL2 LRRK2 ITPR3 FREM2 DLC1 MPP7

3.64e-051931426738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

DENND2A ROR2 RYR2 PTPRD LRFN5 ROBO2

3.64e-051931426acad568621ed677031797b8c2e34dafea798d681
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GTF2IRD1 PTPRD SYNE2 PATJ CDH6 NPAS2

3.74e-0519414267002937e8903e037332a215d00fbc7c7843b33f2
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LRRK2 FREM2 DLC1 PTPRD PATJ MPP7

3.74e-05194142697534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF1A COL20A1 ITPR3 CORO2B DLC1 CDH6

3.85e-0519514269fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 DLC1

3.96e-0519614267e5addaa844e66f8160e05858c341866a80aed23
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 OBSCN RYR2 XIRP2 SMARCD3 ASB2

3.96e-051961426a582130862bee76c0385156a333bfdfc75cf218b
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 OBSCN RYR2 XIRP2 SMARCD3 ASB2

3.96e-051961426fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CDK20 ROR2 RYR2 KIF7 PTPRD LRFN5

3.96e-051961426614a07334707eafe238d5cb7b080a3ca796a1920
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 GTF2IRD1 PROM1 FREM2 PAX2 PATJ

3.96e-0519614266ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

DENND2A ROR2 RYR2 DLC1 LRFN5 ROBO2

3.96e-051961426bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellIPF-Stromal-Pericyte|IPF / Disease state, Lineage and Cell class

DENND2A AVPR1A RYR2 EHD2 DLC1 CDH6

3.96e-0519614268b6ff47ce5291d223f5e639fc45cd9267f418256
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A SYN3 ROR2 RYR2 LRFN5 ROBO2

3.96e-0519614267d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOVID-19-Heart-Mito_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

XIRP1 OBSCN RYR2 XIRP2 ALPK3 PINK1

4.08e-05197142644e49943d62bfe622b40ad0460093d31540544df
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 DLC1

4.08e-051971426bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

DENND2A ROR2 RYR2 PTPRD LRFN5 ROBO2

4.19e-051981426df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND2A SYN3 ROR2 RYR2 LRFN5 ROBO2

4.19e-0519814268f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CDKL2 LRRK2 ESYT3 FREM2 DLC1 MPP7

4.31e-051991426725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Intermediate|GW10 / Sample Type, Dataset, Time_group, and Cell type.

DENND2A PRX XIRP2 MAEL SYTL1 NPAS2

4.31e-051991426cf592d93612023a13de21e0fb8c6b13714f9af71
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 DLC1

4.31e-0519914262dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

OBSCN CCDC57 RYR2 SPTBN4 PROM1 EXD3

4.43e-05200142661d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 MPP7

4.43e-0520014263c251ad03fbbdae91dfd9037880ba43adbb03807
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DENND2A OBSCN PCDHA10 RYR2 SYNE2 CDH6

4.43e-0520014260c648941447c738caf62f2d71e296d6cca492c8b
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-2|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 MPP7

4.43e-052001426c905451425d1c24773bb0ca69bcf0309b277d2f1
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A SYN3 ROR2 RYR2 LRFN5 ROBO2

4.43e-052001426e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DENND2A OBSCN PCDHA10 RYR2 SYNE2 CDH6

4.43e-052001426522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-2|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CDKL2 LRRK2 ITPR3 ESYT3 FREM2 MPP7

4.43e-05200142635c05cae30cd6b323d2662f1396ddeab08bc75fc
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DENND2A RYR2 PROM1 ROBO2 ASB2 CDH6

4.43e-05200142667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

ERBB2 USP28 USP24 ADAR SYNE2 NBPF10

4.43e-0520014262281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DENND2A OBSCN PCDHA10 RYR2 SYNE2 CDH6

4.43e-05200142694f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

OBSCN CCDC57 RYR2 SPTBN4 PROM1 EXD3

4.43e-0520014265c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A ROR2 RYR2 DLC1 LRFN5 ROBO2

4.43e-05200142658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ERBB2 XIRP1 USP24 EFCAB2 RYR1 FREM2

4.43e-052001426be1abe5bb1ce4e7dfec63af4ed0fc5b96bf77866
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)-|Thalamus / BrainAtlas - Mouse McCarroll V32

OTOA CFAP73 TYMP APOBEC4 CCDC180

4.50e-051221425aca079f2f033cc1ac13c4ee02d490b6a514cbd5c
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)--|Thalamus / BrainAtlas - Mouse McCarroll V32

OTOA CFAP73 TYMP APOBEC4 CCDC180

4.50e-051221425ac38130010f76648757eac700a8039f3960ddde3
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL|Thalamus / BrainAtlas - Mouse McCarroll V32

OTOA CFAP73 TYMP APOBEC4 CCDC180

4.50e-0512214257ab0b63244116e74c5783c3293cf08224d094d0a
ToppCellThalamus-Macroglia-CSF_related|Thalamus / BrainAtlas - Mouse McCarroll V32

OTOA CFAP73 TYMP APOBEC4 CCDC180

4.50e-051221425eb944243424460bf5c66aced3ed7b7a1b6486ac7
ToppCellThalamus-Macroglia-CSF_related-EPENDYMAL-Ependymal.Ccdc153_(Ccdc153)|Thalamus / BrainAtlas - Mouse McCarroll V32

OTOA CFAP73 TYMP APOBEC4 CCDC180

4.50e-0512214259b0d6b0a394560ff5aadcd3b21519c2393e6def8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRK2 PEAK3 GREB1L PROM1 CDH6

1.31e-041531425d6526d17826470534b766df144c74e73eb83fdad
Diseasealcohol use disorder (implicated_via_orthology)

ERBB2 DDX17 RYR1 RYR2 PIK3CD SMARCA4 SMARCD1 SMARCD2 SMARCD3

2.07e-071951299DOID:1574 (implicated_via_orthology)
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCD1 SMARCD2 SMARCD3

6.73e-0691293DOID:1925 (implicated_via_orthology)
Diseaseseropositivity measurement, Influenza A seropositivity

SPTBN4 TP53BP1

1.90e-0521292EFO_0007034, EFO_0007038
Diseasecancer (implicated_via_orthology)

DDX17 CAND2 PSMC2 TRIP12 RING1 BRAF PIK3CD SMARCA4

2.47e-052681298DOID:162 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

5.67e-0531292DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

5.67e-0531292DOID:8545 (implicated_via_orthology)
DiseaseAdenocarcinoma of large intestine

ERBB2 ROR2 DLC1 BRAF PRKDC

6.57e-05961295C1319315
DiseaseMalignant tumor of colon

ERBB2 SH3KBP1 TYMP PROM1 BRAF TP53BP1

7.34e-051591296C0007102
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

DNAH10 AGPAT4 APOB SYNE2 SMARCA4 TP53BP1

9.31e-051661296EFO_0004530, EFO_0004611
DiseaseAnhydrotic Ectodermal Dysplasias

BMS1 ITGB4

1.13e-0441292C1706004
Diseasecoronary artery disease, factor VII measurement

PMPCB AGPAT4 APOB MAP1S SMARCA4

1.31e-041111295EFO_0001645, EFO_0004619
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

DNAH10 APOB SYNE2 SMARCA4 TP53BP1

1.31e-041111295EFO_0004530, EFO_0008595
Diseasechronotype measurement

AVPR1A PSMC2 DUS3L ESYT3 EXD3 PTPRD CCDC87 DCHS1 RBM6 ROBO2 PAX5 PATJ NPAS2

1.35e-0488212913EFO_0008328
Diseaselipoprotein A measurement

PMPCB AGPAT4 APOB SMARCA4 FAM124A

1.36e-041121295EFO_0006925
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

AGPAT4 APOB SMARCA4 TP53BP1

1.50e-04611294EFO_0008317, EFO_0008596, EFO_0020946
Diseasevery low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

DNAH10 USP24 AGPAT4 APOB SYNE2 SMARCA4 TP53BP1

1.68e-042641297EFO_0008317, EFO_0020944
Diseasevon Willebrand factor measurement, coronary artery disease

PMPCB AGPAT4 APOB MAP1S SMARCA4

1.74e-041181295EFO_0001645, EFO_0004629
DiseaseCetuximab response

ERBB2 BRAF

1.88e-0451292cv:CN077967
DiseaseHidrotic Ectodermal Dysplasia

BMS1 ITGB4

1.88e-0451292C0162361
DiseasePanitumumab response

ERBB2 BRAF

1.88e-0451292cv:CN077999
DiseaseLymphatic Metastasis

ERBB2 BRAF TP53BP1

1.97e-04261293C0024232
DiseaseCholangiocarcinoma

ERBB2 BRAF ROBO2

1.97e-04261293C0206698
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

USP24 APOB SMARCA4

1.97e-04261293OBA_2045191
DiseaseAutosomal Dominant Parkinsonism

LRRK2 SLC30A10 PINK1

2.47e-04281293C0752098
DiseaseAutosomal Dominant Juvenile Parkinson Disease

LRRK2 SLC30A10 PINK1

2.47e-04281293C0752097
DiseaseParkinsonism, Experimental

LRRK2 SLC30A10 PINK1

2.47e-04281293C0752101
DiseaseAutosomal Recessive Parkinsonism

LRRK2 SLC30A10 PINK1

2.47e-04281293C0752100
DiseaseFamilial Juvenile Parkinsonism

LRRK2 SLC30A10 PINK1

2.47e-04281293C0752104
DiseaseRamsay Hunt Paralysis Syndrome

LRRK2 SLC30A10 PINK1

2.47e-04281293C0242423
DiseasePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

LRRK2 SLC30A10 PINK1

2.47e-04281293C1868675
DiseaseSarcomatoid Renal Cell Carcinoma

ERBB2 LRRK2 RYR1 SPTBN4 SYNE2

2.54e-041281295C1266043
DiseaseChromophobe Renal Cell Carcinoma

ERBB2 LRRK2 RYR1 SPTBN4 SYNE2

2.54e-041281295C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

ERBB2 LRRK2 RYR1 SPTBN4 SYNE2

2.54e-041281295C1266044
DiseasePapillary Renal Cell Carcinoma

ERBB2 LRRK2 RYR1 SPTBN4 SYNE2

2.54e-041281295C1306837
DiseaseRenal Cell Carcinoma

ERBB2 LRRK2 RYR1 SPTBN4 SYNE2

2.54e-041281295C0007134
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

DNAH10 AGPAT4 APOB SYNE2 SMARCA4 TP53BP1

2.56e-042001296EFO_0004611, EFO_0020945
DiseaseColorectal Carcinoma

OBSCN APOB TYMP HPS3 PROM1 CORO2B DLC1 PTPRD BRAF DCHS1 NLRP8

2.68e-0470212911C0009402
DiseaseNeoplasm of uncertain or unknown behavior of ovary

ERBB2 BRAF SMARCA4

2.74e-04291293C0496920
DiseaseEctodermal Dysplasia

BMS1 ITGB4

2.81e-0461292C0013575
DiseaseAplasia Cutis Congenita

BMS1 ITGB4

2.81e-0461292C0282160
DiseaseOvarian Carcinoma

ERBB2 BRAF SMARCA4

3.04e-04301293C0029925
DiseaseParkinsonism, Juvenile

LRRK2 SLC30A10 PINK1

3.04e-04301293C0752105
DiseaseParkinsonian Disorders

LRRK2 SLC30A10 PINK1

3.04e-04301293C0242422
Diseaseovarian neoplasm

ERBB2 DLC1 BRAF SMARCA4 TP53BP1

3.14e-041341295C0919267
Diseasevital capacity

DENND2A CAND2 KIF1A PCDHA10 APOB TRIP12 RYR2 STAU1 PTPRD BRAF PDIK1L SMARCD2 PAX2 DUSP10 PATJ

3.38e-04123612915EFO_0004312
DiseaseMalignant neoplasm of ovary

ERBB2 DLC1 BRAF SMARCA4 TP53BP1

3.48e-041371295C1140680
Diseasepalmitoyl dihydrosphingomyelin (d18:0/16:0) measurement

SYNE2 SMARCA4

3.93e-0471292EFO_0800400
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

USP24 AGPAT4 APOB SYNE2 SMARCA4 TP53BP1

4.47e-042221296EFO_0008317, EFO_0020943
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

DNAH10 AGPAT4 APOB SYNE2 SMARCA4 TP53BP1

4.68e-042241296EFO_0004530, EFO_0008317
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

ERBB2 LRRK2 RYR1 SPTBN4 SYNE2

4.96e-041481295C0279702
Diseaseesterified cholesterol measurement, intermediate density lipoprotein measurement

APOB SMARCA4

5.22e-0481292EFO_0008589, EFO_0008595
DiseaseUnilateral agenesis of kidney

GREB1L FREM2

5.22e-0481292C0266294
Diseasehead and neck squamous cell carcinoma (is_marker_for)

ERBB2 CDC73

5.22e-0481292DOID:5520 (is_marker_for)
Diseasecommon bile duct neoplasm (is_marker_for)

APOB TYMP

5.22e-0481292DOID:4608 (is_marker_for)
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

AGPAT4 APOB SYNE2 SMARCA4 TP53BP1

5.27e-041501295EFO_0004611, EFO_0020947
DiseaseColonic Neoplasms

ERBB2 SH3KBP1 TYMP PROM1 TP53BP1

5.60e-041521295C0009375
Diseaseheart disease (implicated_via_orthology)

RYR2 PIK3CD CNOT4

6.16e-04381293DOID:114 (implicated_via_orthology)
DiseaseNon-Small Cell Lung Carcinoma

ERBB2 ITGB4 BRAF SMARCA4 TP53BP1

6.29e-041561295C0007131
DiseaseTendinopathy

SMARCD1 MPP7

6.69e-0491292EFO_1001434
DiseaseNeoplasm of uncertain or unknown behavior of breast

ERBB2 BRAF SMARCD1

7.71e-04411293C0496956
DiseaseBreast adenocarcinoma

ERBB2 BRAF SMARCD1

7.71e-04411293C0858252
DiseaseHead and Neck Carcinoma

ERBB2 CDC73

8.34e-04101292C3887461
DiseaseMalignant neoplasm of breast

ERBB2 XIRP1 OBSCN ADAR NOP9 PTPRD BRAF SYNE2 SMARCD1 FGD5 RUSF1 TP53BP1 NLRP8

8.74e-04107412913C0006142
Diseasetriglycerides in large LDL measurement

APOB SYNE2 TP53BP1

8.87e-04431293EFO_0022319
Diseasefree cholesterol to total lipids in very small VLDL percentage

APOB SMARCA4 TP53BP1

8.87e-04431293EFO_0022290
Diseasesaturated fatty acids measurement

APOB SMARCA4 TP53BP1

1.01e-03451293EFO_0022304
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

APOB SYNE2 SMARCA4 TP53BP1

1.10e-031031294EFO_0008595, EFO_0020944
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE2 HOOK2

1.22e-03121292DOID:11726 (implicated_via_orthology)
DiseaseHirschsprung's disease (implicated_via_orthology)

ERBB2 PINK1

1.22e-03121292DOID:10487 (implicated_via_orthology)
Diseasetriglycerides to total lipids in medium LDL percentage

APOB SMARCA4 TP53BP1

1.38e-03501293EFO_0022334
Diseaseputamen volume change measurement

TOR2A DCHS1

1.43e-03131292EFO_0021495
DiseaseCarcinogenesis

ERBB2 BRAF

1.43e-03131292C0596263
Diseasetriglycerides to total lipids in large LDL percentage

APOB SMARCA4 TP53BP1

1.46e-03511293EFO_0022331
Diseasephospholipids in very small VLDL measurement

APOB SMARCA4 TP53BP1

1.46e-03511293EFO_0022300
DiseasePR interval

USP28 OBSCN RYR2 FREM2 CORO2B DLC1 SYNE2 ALPK3

1.54e-034951298EFO_0004462
Diseasefactor VIII measurement, coronary artery disease

AGPAT4 APOB MAP1S SMARCA4

1.55e-031131294EFO_0001645, EFO_0004630
DiseaseNeoplasm of lung

ERBB2 BRAF

1.67e-03141292cv:C0024121
Diseasecerebellum cortex volume change measurement

SYN3 PTPRD

1.67e-03141292EFO_0021497
DiseaseLung cancer

ERBB2 BRAF

1.67e-03141292cv:C0242379
DiseaseLUNG CANCER

ERBB2 BRAF

1.67e-03141292211980
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

APOB SMARCA4

1.67e-03141292EFO_0004611, EFO_0008589
DiseaseMetastatic melanoma

GUCY2D ALPK3 PRKDC

1.72e-03541293C0278883
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

DNAH10 USP24 APOB SYNE2 SMARCA4 TP53BP1

1.81e-032911296EFO_0008317, EFO_0020946
Diseasetriglycerides in medium VLDL measurement

DNAH10 APOB TP53BP1

1.81e-03551293EFO_0022155
Diseaseleukemia

PPP1R13L CFLAR BRAF

1.81e-03551293C0023418
Diseasetriglycerides in large VLDL measurement

DNAH10 APOB TP53BP1

1.91e-03561293EFO_0022178
Diseasetriglycerides in LDL measurement

APOB SYNE2 TP53BP1

1.91e-03561293EFO_0022320
DiseaseGeneralized hypotonia

AP2M1 SMARCD1

1.92e-03151292C1858120
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

APOB SYNE2 SMARCA4 TP53BP1

2.00e-031211294EFO_0008595, EFO_0020943
DiseaseHypertrophic Cardiomyopathy

OBSCN RYR2 ALPK3

2.01e-03571293C0007194
Diseaseidiopathic scoliosis (implicated_via_orthology)

DNAH10 KIF7

2.19e-03161292DOID:0060250 (implicated_via_orthology)
Diseasephospholipids in small VLDL measurement

APOB SMARCA4 TP53BP1

2.33e-03601293EFO_0022146
Diseaseobsolete_red blood cell distribution width

SYN3 RC3H1 RMI2 APOB TYMP PLEKHG5 SLC4A1 ESYT3 SYNE2 RBM6 LRRC14 HOOK2 ATP2B3 SLC30A10

2.33e-03134712914EFO_0005192
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

APOB SYNE2 SMARCA4 TP53BP1

2.38e-031271294EFO_0008595, EFO_0020947
Diseasetriglycerides in small VLDL measurement

DNAH10 APOB TP53BP1

2.44e-03611293EFO_0022145
Diseasefree cholesterol in very large VLDL measurement

DNAH10 APOB TP53BP1

2.44e-03611293EFO_0022274
DiseaseDisorder of eye

OAT KIF7 PROM1 FREM2 GUCY2D

2.45e-032121295C0015397
DiseaseBenign neoplasm of stomach

ERBB2 BRAF

2.47e-03171292C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB2 BRAF

2.47e-03171292C0496905
DiseaseCarcinoma in situ of stomach

ERBB2 BRAF

2.47e-03171292C0154060

Protein segments in the cluster

PeptideGeneStartEntry
IPAREIPDLLEKGER

ERBB2

926

P04626
LRVILEPLLVDKPFV

ESYT3

221

A0FGR9
RDERPLFPQILASIE

BRAF

701

P15056
ESLLNPELIRPFILE

CDK20

331

Q8IZL9
ENIPVVRRPDRKDLL

CDC73

81

Q6P1J9
AELEAVELPVPIRFL

SLC4A1

251

P02730
DPNRDVISPLLVAIR

ASB2

436

Q96Q27
DLRAPVVFVLVPLRD

APOBEC4

286

Q8WW27
PLLVPDNRRLFELEE

EHD2

261

Q9NZN4
EDDPLRRPITIALVE

FBXO10

711

Q9UK96
PQVIRKIRVEQFPDA

ALPK3

1476

Q96L96
ITEQELPERRKALRP

DNMBP

596

Q6XZF7
VPVGLLERLPQRINE

DUS3L

586

Q96G46
FPENRSPEEIREKIL

ADCY10

1021

Q96PN6
EDPAVDVIRKLLQLP

CCDC180

1251

Q9P1Z9
PPEARLRLIKVILDE

CCDC87

76

Q9NVE4
EDHVPPVLRLLEKRQ

CFAP73

26

A6NFT4
PAVIREPHERKILAL

BMS1

1196

Q14692
DVVPPNVRDLLDILR

CFLAR

31

O15519
RDFQPVREQIPEDKL

ATP2B3

556

Q16720
VLVLFVVQRLEPRFP

RC3H1

221

Q5TC82
KPLPSAEREQLRLEL

RC3H1

956

Q5TC82
TNVPIDIEEERPIRL

ITPR3

401

Q14573
RPLPDVVRQRIVELA

PAX5

31

Q02548
QVLESRLQRPLPEDL

LRCH4

546

O75427
PPNIDRRTVELRLAD

LRFN5

46

Q96NI6
VRVERRQELALEDPP

NPAS2

356

Q99743
FLQPDITERLPRDLR

OTOA

191

Q7RTW8
RRIPIPELEARIDAV

PMPCB

431

O75439
RPLDREVEPAFQLRI

DCHS1

1811

Q96JQ0
RPIPEDVLLRAFEVL

EFCAB2

226

Q5VUJ9
LLVLEPPRLQSLFEE

NOP9

336

Q86U38
LRFLREPVVTPQDLE

MAP1S

451

Q66K74
QEKIPELRRRGLPVA

MAEL

16

Q96JY0
ISLQEIPPERRRKLE

GUCY2D

1081

Q02846
VVRREINAILPTLEP

NLRP8

116

Q86W28
QAPVTEILRQPERLL

NLRP10

231

Q86W26
EILRQPERLLFILDG

NLRP10

236

Q86W26
ELQRKREYIEELEPP

HOOK2

556

Q96ED9
LLFVPPAIDRRVVEL

LRFN1

56

Q9P244
PITLRVNVRPVDDEV

FREM2

926

Q5SZK8
VQEEVRALRLCPLEP

CARMIL3

696

Q8ND23
RALRLCPLEPVQDEL

CARMIL3

701

Q8ND23
LDDRVVVALSRPVRP

DUSP10

6

Q9Y6W6
RGRPLDDIIDKLPEI

ECPAS

1191

Q5VYK3
FRVRDIGELVPLLPN

FAM124A

241

Q86V42
ESVPPDVRQLVRALL

PINK1

476

Q9BXM7
ALVELRPENLLLVAP

PEAK3

301

Q6ZS72
IVVPRVPLREDEPKD

FGD5

66

Q6ZNL6
IPVEDKRPEEIIQIL

MPP7

191

Q5T2T1
AEEAPVRVALRVRPL

KIF7

11

Q2M1P5
VPIEFPVIDRKRLLQ

LRRK2

1541

Q5S007
KDIILPFRVIPLVRE

AP2M1

281

Q96CW1
PLPLEKEEQVRLQAR

GOLGA3

141

Q08378
LVRLGPDQVPLREEF

GREB1L

461

Q9C091
LVDVRVPLFIRPEDD

ITGB4

941

P16144
LELRVRVLDINDNPP

DSG1

141

Q02413
RPLPDVVRQRIVELA

PAX2

31

Q02962
PVLVLRKLLDREENP

PCDHA10

191

Q9Y5I2
IVRERPAAIIKPLED

OBSCN

2821

Q5VST9
AGVRLPEIKEREPLE

CDKL2

236

Q92772
LKVEDIPLARITLPD

APOB

2696

P04114
LRRPVNVPLDIFLEE

KCNA6

106

P17658
LLENVPPRTENELLR

CORO2B

426

Q9UQ03
VIKLENRQEARPEPA

ADAR

416

P55265
QREISPEEPLRRLQE

BIRC8

171

Q96P09
PLLRELPLEEVLVVD

DENND2A

826

Q9ULE3
IVFLVRLLPETPREA

COL20A1

901

Q9P218
RLRQKVLREPLEPAA

CCDC57

676

Q2TAC2
VLREPLEPAALQREL

CCDC57

681

Q2TAC2
REAVLIDPVLETAPR

ETHE1

46

O95571
FEPQIRKILLDVRPD

DDX53

386

Q86TM3
NKLRRDIVPEALFLP

CDH6

686

P55285
PNEDIVERNIRIIVP

JCHAIN

51

P01591
EPQIRKIVDQIRPDR

DDX17

336

Q92841
LRPIKIEPEDLDIIQ

GTF2IRD1

491

Q9UHL9
PIEVIRPDIAALVRQ

GPX8

186

Q8TED1
APVLQRVDRLIEPLR

CAND2

1141

O75155
PELSPEEQRVLERKL

C7orf50

56

Q9BRJ6
DILEREIPLSQPFRL

DNAH10

3381

Q8IVF4
VLPPHLERIREKLAE

RYR1

861

P21817
QIVLPPHLERIREKL

RYR2

871

Q92736
ELEEVARVLAEIPRP

PPP1R13L

506

Q8WUF5
EIELVFRPHPLLVEK

RING1

261

Q06587
LLREKLETAQRPVPE

KIF1A

1396

Q12756
RLLVPDIQEIRVSPI

KIF1A

1561

Q12756
VLRIQPLRTPRDEAI

PTPRD

81

P23468
ELKDELPERQPRFIV

GMFB

56

P60983
PLPAELEELRNRVRA

RUSF1

396

Q96GQ5
KLREVVETPLLHPER

PSMC2

186

P35998
EPRLTIDEAPQERLR

SYTL1

136

Q8IYJ3
PIVQRPRILLVIDDA

SYN3

86

O14994
EALRVVKILQNLDPP

RBM6

711

P78332
PPLKVLAEQLRRDAE

RMI2

21

Q96E14
KILPQRIRELVPESQ

SMARCD1

131

Q96GM5
FRIAEQELKIPRLLE

SYNE2

246

Q8WXH0
ILLTKAEPEAIPERR

HPS3

446

Q969F9
PRLSRELLEVVEPEV

NBPF9

936

P0DPF3
PRLSRELLEVVEPEV

NBPF10

1011

Q6P3W6
PRLSRELLEVVEPEV

NBPF10

2231

Q6P3W6
PRLSRELLEVVEPEV

NBPF10

3451

Q6P3W6
PRLSRELLEVVEPEV

NBPF14

746

Q5TI25
PRLSRELLEVVEPEV

NBPF15

496

Q8N660
PRLSRELVEVVEPEV

NBPF19

496

A0A087WUL8
PRLSRELLEVVEPEV

NBPF19

1716

A0A087WUL8
PRLSRELLEVVEPEV

NBPF19

2936

A0A087WUL8
PRLSRELLEVVEPEV

NBPF20

396

P0DPF2
PRLSRELLEVVEPEV

NBPF20

1616

P0DPF2
PRLSRELLEVVEPEV

NBPF20

2836

P0DPF2
PRLSRELLEVVEPEV

NBPF20

4056

P0DPF2
PQDRPDAFELELRLV

PDIK1L

316

Q8N165
ILDRLRPNIIPVLDE

PROM1

241

O43490
LRPRSIEVENDFLPV

SH3KBP1

226

Q96B97
QKPRGLDPVEILQER

SMARCA4

356

P51532
KILPQRIRELVPESQ

SMARCD3

106

Q6STE5
LKNDAPVVQEPRRII

ROR2

96

Q01974
VIEVPAVPEEILKRL

DLC1

1371

Q96QB1
IIRFAPPLVIKEDEL

OAT

411

P04181
ADKVLPQRIRELVPE

SMARCD2

141

Q92925
ALVPREREPKLSILQ

C11orf40

6

Q8WZ69
LSQRLADPEVLKRPE

CNOT4

116

O95628
LRIPQERLQATEEPR

ZNF837

211

Q96EG3
DAVEIIRKVAVPPRL

XIRP2

3116

A4UGR9
ERLLDAVVPFLPLQR

TOR2A

251

Q5JU69
PRRPGEEAELLVKLD

TNRC18

2451

O15417
AERTRVIRPPLLVDK

PLEKHG5

621

O94827
VLRLARPERIDDPEL

SLC30A10

101

Q6XR72
LRERIQPEEKPVEVS

SPART

456

Q8N0X7
ILIIPTPDEEEKILR

ZNF24

11

P17028
RPPRETVRLELVLKD

UBN2

121

Q6ZU65
LRRVQDVKLQPPEVV

TRIM11

251

Q96F44
PLIQLVRRPVEVLQD

REV3L

2961

O60673
VRRPVEVLQDPTLRL

REV3L

2966

O60673
ALRILQNEPLPERLE

STAU1

156

O95793
PSLLIDLPVVAQRRE

PATJ

996

Q8NI35
AVPEVRLPEVQLLKV

PRX

511

Q9BXM0
AVPLIQPDLRREEAV

WASH2P

16

Q6VEQ5
LQSREEKQEPVVVRP

SAP130

86

Q9H0E3
AVPLIQPDLRREEAV

WASH3P

16

C4AMC7
DVQPFLPVLRLVARE

PIK3CD

91

O00329
QELKPERLQPRIDRL

SPTBN4

2181

Q9H254
VEDRLRAIVADPRVP

TEX13C

46

A0A0J9YWL9
EALEIPRPLRALDQT

ROBO2

1226

Q9HCK4
PLVRADDPLRLDQEL

TP53BP1

836

Q12888
PRLLDPSAEIIVLKE

USP28

1031

Q96RU2
PPRDVRNEELAKLEI

AVPR1A

41

P37288
LKPVELRELLNPVVE

PRKDC

2446

P78527
LIELVAERIKQDPIP

USP24

211

Q9UPU5
ADLYVRRIPLEDIPE

AGPAT4

251

Q9NRZ5
PVKIDPLALVQAIER

TRIP12

1286

Q14669
ELPRIICQVLRRPDV

XIRP1

826

Q702N8
LLPRAREQEELLAPA

TYMP

371

P19971
PRKTREPFILEENEI

VPS13D

1346

Q5THJ4
APIPVEVRVDLRVNR

LRRC14

161

Q15048
IIDEPIRPVNIPRKE

MYO5A

1456

Q9Y4I1
PEERLPAAVAVELRR

EXD3

326

Q8N9H8