Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionzinc ion binding

ZSWIM8 KMT2B RNF31 PRICKLE1 TRIM75 KDM5C NSD1 CBLC ZC3HC1 GATA5 ADAMTS8 USP44 PHF2 ZCCHC4 TRIM33 PRICKLE3 SMPDL3A TRIM17 ARIH2 NFX1 TRIM60

2.90e-0889111421GO:0008270
GeneOntologyMolecularFunctionhistone modifying activity

KMT2B ATR KDM5C NSD1 KDM3B EZH1 JMJD1C NSD3 PHF2 KMT2C KDM4B

8.11e-0822911411GO:0140993
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5C KDM3B JMJD1C PHF2 KDM4B

4.91e-07281145GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5C KDM3B JMJD1C PHF2 KDM4B

8.38e-07311145GO:0032452
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

KDM3B JMJD1C PHF2 KDM4B

9.65e-07141144GO:0032454
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5C KDM3B JMJD1C PHF2 KDM4B

9.89e-07321145GO:0140457
GeneOntologyMolecularFunctiontransition metal ion binding

ZSWIM8 KMT2B RNF31 PRICKLE1 TRIM75 KDM5C NSD1 CBLC ZC3HC1 GATA5 ADAMTS8 USP44 PHF2 ZCCHC4 TRIM33 PRICKLE3 SMPDL3A TRIM17 ARIH2 NFX1 TRIM60

3.32e-06118911421GO:0046914
GeneOntologyMolecularFunctiondemethylase activity

KDM5C KDM3B JMJD1C PHF2 KDM4B

5.05e-06441145GO:0032451
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

KMT2B NSD1 EZH1 NSD3 KMT2C

5.05e-06441145GO:0140938
GeneOntologyMolecularFunctioncalcium ion binding

SPOCK1 CBLC TTYH3 LRP1B JAG2 NELL1 THBS1 NOTCH2NLB MEGF8 PLA2G2D UMODL1 SPOCK3 UMOD NOTCH2 NOTCH4 CRB2

5.48e-0674911416GO:0005509
GeneOntologyMolecularFunctionubiquitin protein ligase activity

RNF31 TRIM75 CBLC TRIM33 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

9.38e-0637211411GO:0061630
GeneOntologyMolecularFunctionpeptidase inhibitor activity

CRIM1 SPOCK1 SSPOP THBS1 UMODL1 SPOCK3 SERPINC1 CRB2

1.20e-051871148GO:0030414
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RNF31 TRIM75 CBLC TRIM33 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

1.76e-0539811411GO:0061659
GeneOntologyMolecularFunctionprotein methyltransferase activity

KMT2B NSD1 EZH1 LCMT2 NSD3 KMT2C

2.76e-051031146GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

KMT2B NSD1 EZH1 NSD3 ZCCHC4 KMT2C

3.08e-051051146GO:0008170
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

KMT2B NSD1 EZH1 NSD3 KMT2C

4.35e-05681145GO:0016279
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

KMT2B NSD1 EZH1 NSD3 KMT2C

4.66e-05691145GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

KMT2B NSD1 EZH1 NSD3 KMT2C

5.35e-05711145GO:0042054
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

RNF31 TRIM75 CBLC TRIM33 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

8.42e-0547311411GO:0004842
GeneOntologyMolecularFunctionhistone H3K27 trimethyltransferase activity

EZH1 NSD3

9.66e-0531142GO:0140951
GeneOntologyMolecularFunctionpeptidase regulator activity

CRIM1 SPOCK1 SSPOP THBS1 UMODL1 SPOCK3 SERPINC1 CRB2

1.15e-042571148GO:0061134
GeneOntologyMolecularFunctionacyltransferase activity

RNF31 TRIM75 CBLC ZDHHC1 TRIM33 KMT2C ZDHHC23 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

1.34e-0477511414GO:0016746
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RNF31 TRIM75 CBLC TRIM33 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

1.69e-0451211411GO:0019787
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

KMT2B NSD3 KMT2C

1.92e-04201143GO:0042800
GeneOntologyMolecularFunctionmethyltransferase activity

KMT2B NSD1 EZH1 LCMT2 NSD3 ZCCHC4 KMT2C

2.23e-042131147GO:0008168
GeneOntologyMolecularFunctionaminoacyltransferase activity

RNF31 TRIM75 CBLC TRIM33 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

2.35e-0453211411GO:0016755
GeneOntologyMolecularFunctiondioxygenase activity

KDM5C KDM3B JMJD1C PHF2 KDM4B

2.47e-04981145GO:0051213
GeneOntologyMolecularFunctiontransferase activity, transferring one-carbon groups

KMT2B NSD1 EZH1 LCMT2 NSD3 ZCCHC4 KMT2C

3.03e-042241147GO:0016741
GeneOntologyMolecularFunctionS-adenosylmethionine-dependent methyltransferase activity

KMT2B NSD1 EZH1 NSD3 ZCCHC4 KMT2C

4.63e-041721146GO:0008757
GeneOntologyMolecularFunctionhistone H3K27 methyltransferase activity

EZH1 NSD3

4.77e-0461142GO:0046976
GeneOntologyMolecularFunctionNotch binding

JAG2 NOTCH2NLB NOTCH4

4.80e-04271143GO:0005112
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5C KDM3B PHF2 KDM4B

5.22e-04651144GO:0016706
GeneOntologyMolecularFunctionendopeptidase inhibitor activity

CRIM1 SPOCK1 THBS1 SPOCK3 SERPINC1 CRB2

5.89e-041801146GO:0004866
GeneOntologyMolecularFunctionextracellular matrix structural constituent

VWF LAMA3 SSPOP THBS1 TINAG MEGF9

7.39e-041881146GO:0005201
GeneOntologyMolecularFunctionsignaling receptor regulator activity

IL37 WNT1 WNT9A WNT9B TG JAG2 RETN RETNLB LY6H SLURP2 DKK3

8.01e-0461611411GO:0030545
GeneOntologyMolecularFunctionhistone H3K4 monomethyltransferase activity

KMT2B KMT2C

8.85e-0481142GO:0140945
GeneOntologyMolecularFunctionendopeptidase regulator activity

CRIM1 SPOCK1 THBS1 SPOCK3 SERPINC1 CRB2

1.05e-032011146GO:0061135
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

KMT2B KMT2C

1.41e-03101142GO:0140999
GeneOntologyMolecularFunctionfrizzled binding

WNT1 WNT9A WNT9B

1.77e-03421143GO:0005109
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXND1 PLXNB3

2.05e-03121142GO:0017154
GeneOntologyMolecularFunctionmolecular function inhibitor activity

CRIM1 SPOCK1 SSPOP THBS1 UMODL1 SPOCK3 SERPINC1 LY6H DKK3 CRB2

2.20e-0359611410GO:0140678
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

NSD1 NSD3

2.42e-03131142GO:0046975
GeneOntologyMolecularFunctionco-receptor binding

WNT9B DKK3

2.42e-03131142GO:0039706
GeneOntologyMolecularFunctionmuscle alpha-actinin binding

PDLIM5 LDB3

3.23e-03151142GO:0051371
GeneOntologyMolecularFunctionenzyme inhibitor activity

CRIM1 SPOCK1 SSPOP THBS1 UMODL1 SPOCK3 SERPINC1 CRB2

3.51e-034351148GO:0004857
GeneOntologyMolecularFunctionacetylcholine receptor binding

LY6H SLURP2

3.68e-03161142GO:0033130
GeneOntologyMolecularFunctionmetalloendopeptidase inhibitor activity

SPOCK1 SPOCK3

3.68e-03161142GO:0008191
GeneOntologyMolecularFunctionglycosaminoglycan binding

ADAMTS8 NELL1 THBS1 PLA2G2D SPOCK3 SERPINC1

4.41e-032681146GO:0005539
GeneOntologyMolecularFunctionheparin binding

ADAMTS8 NELL1 THBS1 PLA2G2D SERPINC1

4.92e-031921145GO:0008201
GeneOntologyMolecularFunctiontranscription coregulator activity

NSD1 KDM3B EZH1 JMJD1C PHF2 KMT2C TLE1 FHL2 FHL5

4.93e-035621149GO:0003712
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

4.98e-031201144GO:0004222
GeneOntologyMolecularFunctionprotein kinase C binding

PDLIM5 NELL1 LDB3

6.39e-03661143GO:0005080
GeneOntologyBiologicalProcessresponse to BMP

CRIM1 WNT1 KCP GATA5 ADAMTS12 TRIM33 MEGF8 ADAMTS7 VWC2L NOTCH2 CRB2

2.80e-0821511311GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

CRIM1 WNT1 KCP GATA5 ADAMTS12 TRIM33 MEGF8 ADAMTS7 VWC2L NOTCH2 CRB2

2.80e-0821511311GO:0071773
GeneOntologyBiologicalProcesscornea development in camera-type eye

PRICKLE1 WNT9A WNT9B LIMK2

1.48e-06161134GO:0061303
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

CRIM1 WNT1 KCP TRIM33 VWC2L NOTCH2 CRB2

7.84e-061311137GO:0030510
GeneOntologyBiologicalProcessprotein ubiquitination

ZSWIM8 RNF31 PRICKLE1 TRIM75 CBLC ZC3HC1 USP44 TRIM33 MEGF8 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

8.84e-0681111316GO:0016567
GeneOntologyBiologicalProcessBMP signaling pathway

CRIM1 WNT1 KCP TRIM33 MEGF8 VWC2L NOTCH2 CRB2

1.31e-051971138GO:0030509
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

ZSWIM8 RNF31 PRICKLE1 TRIM75 CBLC ZC3HC1 USP44 TRIM33 MEGF8 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

2.88e-0589311316GO:0032446
GeneOntologyBiologicalProcessgastrulation with mouth forming second

PRICKLE1 NSD1 MEGF8 CRB2

3.92e-05351134GO:0001702
GeneOntologyBiologicalProcesschromatin remodeling

KMT2B ATR KDM5C NSD1 KDM3B EZH1 JMJD1C NSD3 PHF1 PHF2 KMT2C SHPRH CENPV KDM4B

5.40e-0574111314GO:0006338
GeneOntologyBiologicalProcesspost-translational protein modification

ZSWIM8 RNF31 PRICKLE1 TRIM75 CBLC ZC3HC1 LCMT2 USP44 TRIM33 MEGF8 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

7.50e-05107411317GO:0043687
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

CRIM1 WNT1 KCP ADAMTS12 TRIM33 THBS1 VWC2L DKK3 NOTCH2 CRB2

9.03e-0541211310GO:0090287
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

ZSWIM8 RNF31 PRICKLE1 TRIM75 CBLC ZC3HC1 USP44 TRIM33 MEGF8 TRIM17 ARIH2 NFX1 SHPRH HERC3 RFPL2 TRIM60

1.22e-04100911316GO:0070647
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

CRIM1 WNT1 KCP TRIM33 THBS1 VWC2L DKK3 NOTCH2 CRB2

1.25e-043471139GO:0090092
GeneOntologyBiologicalProcesscell fate determination

WNT1 JAG2 NOTCH2 NOTCH4

1.62e-04501134GO:0001709
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

CRIM1 WNT1 KCP TRIM33 THBS1 MEGF8 VWC2L DKK3 NOTCH2 CRB2

1.69e-0444511310GO:0141091
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

CRIM1 WNT1 ADAMTS12 TRIM33 THBS1 VWC2L

1.78e-041501136GO:0090288
GeneOntologyBiologicalProcessanimal organ morphogenesis

PRICKLE1 WNT1 WNT9A WNT9B LAMA3 GATA5 PLXND1 LIMS2 JAG2 THBS1 MEGF8 TENM3 MEGF9 TLE1 LY6H FHL2 NOTCH2 CRB2

1.81e-04126911318GO:0009887
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

WNT1 GATA5 JAG2 NOTCH2NLB

2.03e-04531134GO:0045747
GeneOntologyBiologicalProcessmethylation

KMT2B NSD1 EZH1 LCMT2 NSD3 ZCCHC4 KMT2C

3.08e-042341137GO:0032259
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

CRIM1 WNT1 KCP TRIM33 THBS1 MEGF8 VWC2L DKK3 NOTCH2 CRB2

3.21e-0448211310GO:0007178
GeneOntologyBiologicalProcessresponse to growth factor

CRIM1 WNT1 KCP CBLC GATA5 ADAMTS12 TRIM33 THBS1 MEGF8 ADAMTS7 VWC2L DKK3 NOTCH2 CRB2

3.35e-0488311314GO:0070848
GeneOntologyBiologicalProcesschromatin organization

KMT2B ATR KDM5C NSD1 KDM3B EZH1 JMJD1C NSD3 PHF1 PHF2 KMT2C SHPRH CENPV KDM4B

3.88e-0489611314GO:0006325
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

WNT1 GATA5 JAG2 NOTCH2NLB NOTCH4

4.12e-041141135GO:0008593
GeneOntologyBiologicalProcessnegative regulation of chondrocyte differentiation

WNT9A ADAMTS12 ADAMTS7

4.25e-04271133GO:0032331
GeneOntologyBiologicalProcessrenal tubule development

PRICKLE1 WNT1 WNT9B UMOD NOTCH2

4.47e-041161135GO:0061326
GeneOntologyBiologicalProcessembryonic brain development

PRICKLE1 WNT1 MEGF8

5.27e-04291133GO:1990403
GeneOntologyBiologicalProcesscell fate commitment

WNT1 WNT9A WNT9B ISL2 GATA5 JAG2 NOTCH2 NOTCH4

5.51e-043381138GO:0045165
GeneOntologyBiologicalProcesscamera-type eye development

PRICKLE1 WNT9A WNT9B KMT2C LIMK2 PYGO2 TENM3 NOTCH2 CRB2

5.65e-044261139GO:0043010
GeneOntologyCellularComponenthistone methyltransferase complex

KMT2B NSD1 EZH1 PHF1 KMT2C

5.39e-05751135GO:0035097
GeneOntologyCellularComponentextracellular matrix

VWF LAMA3 ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 TINAG MEGF9 ADAMTS7 SPOCK3 SERPINC1

2.27e-0465611312GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

VWF LAMA3 ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 TINAG MEGF9 ADAMTS7 SPOCK3 SERPINC1

2.33e-0465811312GO:0030312
GeneOntologyCellularComponentmethyltransferase complex

KMT2B NSD1 EZH1 PHF1 KMT2C

3.02e-041081135GO:0034708
MousePhenorenal glomerulus cyst

CRIM1 WNT9B PLXND1 UMOD

8.46e-0621894MP:0011682
DomainEGF_1

ADAM20 LAMA3 SSPOP LRP1B JAG2 NELL1 THBS1 MEGF8 TENM3 MEGF9 UMODL1 CNTNAP4 UMOD NOTCH2 NOTCH4 CRB2 PEAR1

1.45e-1325511017PS00022
DomainPHD

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 SHPRH KDM4B

1.53e-138911012SM00249
DomainZnf_PHD

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 SHPRH KDM4B

2.02e-139111012IPR001965
DomainEGF_2

ADAM20 LAMA3 SSPOP LRP1B JAG2 NELL1 THBS1 MEGF8 TENM3 MEGF9 UMODL1 CNTNAP4 UMOD NOTCH2 NOTCH4 CRB2 PEAR1

2.72e-1326511017PS01186
DomainZF_PHD_2

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 SHPRH KDM4B

3.43e-139511012PS50016
DomainZF_PHD_1

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 SHPRH KDM4B

3.90e-139611012PS01359
DomainPHD

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 KDM4B

6.34e-137511011PF00628
DomainZnf_PHD-finger

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 NFX1

1.15e-127911011IPR019787
DomainEGF-like_dom

ADAM20 LAMA3 LRP1B JAG2 NELL1 THBS1 MEGF8 TENM3 MEGF9 UMODL1 CNTNAP4 UMOD NOTCH2 NOTCH4 CRB2 PEAR1

1.41e-1224911016IPR000742
DomainEGF-like_CS

ADAM20 LAMA3 LRP1B JAG2 NELL1 THBS1 MEGF8 TENM3 MEGF9 UMODL1 CNTNAP4 UMOD NOTCH2 NOTCH4 CRB2 PEAR1

2.89e-1226111016IPR013032
DomainZinc_finger_PHD-type_CS

TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 PYGO2 NFX1 SHPRH

4.52e-126511010IPR019786
DomainEGF

LAMA3 LRP1B JAG2 NELL1 THBS1 MEGF8 TENM3 MEGF9 UMODL1 CNTNAP4 UMOD NOTCH2 NOTCH4 CRB2 PEAR1

8.17e-1223511015SM00181
DomainEGF_3

ADAM20 SSPOP LRP1B JAG2 NELL1 THBS1 MEGF8 TENM3 UMODL1 CNTNAP4 UMOD NOTCH2 NOTCH4 CRB2 PEAR1

8.17e-1223511015PS50026
DomainVWFC_1

VWF CRIM1 KCP SSPOP JAG2 NELL1 THBS1 VWC2L

2.95e-11361108PS01208
DomainVWFC_2

VWF CRIM1 KCP SSPOP JAG2 NELL1 THBS1 VWC2L

4.72e-11381108PS50184
DomainVWC

VWF CRIM1 KCP SSPOP JAG2 NELL1 THBS1 VWC2L

4.72e-11381108SM00214
DomainZnf_FYVE_PHD

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 SHPRH KDM4B

6.52e-1114711012IPR011011
DomainVWF_dom

VWF CRIM1 KCP SSPOP JAG2 NELL1 THBS1 VWC2L

1.12e-10421108IPR001007
Domain-

KMT2B TCF19 KDM5C NSD1 CBLC NSD3 USP44 PHF1 PHF2 TRIM33 KMT2C PYGO2 TRIM17 ARIH2 SHPRH RFPL2 KDM4B TRIM60

1.34e-10449110183.30.40.10
DomainZnf_RING/FYVE/PHD

KMT2B TCF19 KDM5C NSD1 CBLC NSD3 USP44 PHF1 PHF2 TRIM33 KMT2C PYGO2 TRIM17 ARIH2 SHPRH RFPL2 KDM4B TRIM60

1.91e-1045911018IPR013083
DomainLIM

PRICKLE1 ISL2 PDLIM5 LIMS2 LIMK2 LDB3 PRICKLE3 FHL2 FHL5

2.58e-10691109PF00412
Domain-

PRICKLE1 ISL2 PDLIM5 LIMS2 LIMK2 LDB3 PRICKLE3 FHL2 FHL5

2.95e-107011092.10.110.10
DomainLIM

PRICKLE1 ISL2 PDLIM5 LIMS2 LIMK2 LDB3 PRICKLE3 FHL2 FHL5

3.36e-10711109SM00132
DomainZnf_LIM

PRICKLE1 ISL2 PDLIM5 LIMS2 LIMK2 LDB3 PRICKLE3 FHL2 FHL5

3.36e-10711109IPR001781
DomainLIM_DOMAIN_1

PRICKLE1 ISL2 PDLIM5 LIMS2 LIMK2 LDB3 PRICKLE3 FHL2 FHL5

3.36e-10711109PS00478
DomainLIM_DOMAIN_2

PRICKLE1 ISL2 PDLIM5 LIMS2 LIMK2 LDB3 PRICKLE3 FHL2 FHL5

3.36e-10711109PS50023
DomainVWC_out

VWF CRIM1 KCP SSPOP JAG2 NELL1

9.27e-10191106SM00215
DomainEGF_CA

LRP1B JAG2 NELL1 THBS1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4

1.93e-09861109PF07645
DomainEGF_CA

LRP1B JAG2 NELL1 THBS1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4 CRB2

2.63e-0912211010SM00179
DomainEGF-like_Ca-bd_dom

LRP1B JAG2 NELL1 THBS1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4 CRB2

3.09e-0912411010IPR001881
DomainEGF_Ca-bd_CS

LRP1B JAG2 NELL1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4 CRB2

5.68e-09971109IPR018097
DomainEGF_CA

LRP1B JAG2 NELL1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4 CRB2

6.81e-09991109PS01187
DomainASX_HYDROXYL

LRP1B JAG2 NELL1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4 CRB2

7.45e-091001109PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1B JAG2 NELL1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4 CRB2

1.25e-081061109IPR000152
DomainGrowth_fac_rcpt_

CRIM1 LAMA3 LRP1B JAG2 NELL1 MEGF8 UMODL1 UMOD NOTCH2 NOTCH4

2.84e-0815611010IPR009030
DomainRING

RNF31 NSD1 CBLC NSD3 TRIM33 KMT2C TRIM17 ARIH2 NFX1 SHPRH RFPL2 TRIM60

2.45e-0730511012SM00184
DomainJmjC

KDM5C KDM3B JMJD1C PHF2 KDM4B

2.51e-07241105PF02373
DomainZnf_RING

RNF31 NSD1 CBLC NSD3 TRIM33 KMT2C TRIM17 ARIH2 NFX1 SHPRH RFPL2 TRIM60

4.98e-0732611012IPR001841
DomainVWC

VWF CRIM1 KCP NELL1 THBS1

5.70e-07281105PF00093
DomainJMJC

KDM5C KDM3B JMJD1C PHF2 KDM4B

1.15e-06321105PS51184
DomainJmjC_dom

KDM5C KDM3B JMJD1C PHF2 KDM4B

1.15e-06321105IPR003347
DomainJmjC

KDM5C KDM3B JMJD1C PHF2 KDM4B

1.35e-06331105SM00558
DomainTSP_1

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

1.88e-06631106PF00090
DomainPost-SET_dom

KMT2B NSD1 NSD3 KMT2C

1.96e-06161104IPR003616
DomainPostSET

KMT2B NSD1 NSD3 KMT2C

1.96e-06161104SM00508
DomainPOST_SET

KMT2B NSD1 NSD3 KMT2C

1.96e-06161104PS50868
DomainTSP1

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

2.27e-06651106SM00209
DomainTSP1_rpt

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

2.27e-06651106IPR000884
DomainTSP1

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

2.27e-06651106PS50092
DomainSET

KMT2B NSD1 EZH1 NSD3 KMT2C

4.09e-06411105PF00856
DomainConA-like_dom

LAMA3 NELL1 THBS1 TRIM17 CNTNAP4 ADGRD2 RFPL2 CRB2 TRIM60

5.92e-062191109IPR013320
DomainSET

KMT2B NSD1 EZH1 NSD3 KMT2C

7.31e-06461105SM00317
DomainEGF

LRP1B JAG2 CNTNAP4 UMOD NOTCH2 NOTCH4 CRB2

9.62e-061261107PF00008
DomainZF_RING_2

RNF31 CBLC TRIM33 KMT2C TRIM17 ARIH2 NFX1 SHPRH RFPL2 TRIM60

1.06e-0529811010PS50089
DomainPeptidase_M12B_ADAM-TS

ADAMTS8 ADAMTSL3 ADAMTS12 ADAMTS7

1.11e-05241104IPR013273
DomainSET_dom

KMT2B NSD1 EZH1 NSD3 KMT2C

1.11e-05501105IPR001214
DomainSET

KMT2B NSD1 EZH1 NSD3 KMT2C

1.11e-05501105PS50280
DomainDHHC

ZDHHC1 ZCCHC4 KMT2C ZDHHC23

1.31e-05251104PS50216
DomainZnf_DHHC_palmitoyltrfase

ZDHHC1 ZCCHC4 KMT2C ZDHHC23

1.31e-05251104IPR001594
DomainhEGF

JAG2 NOTCH2 NOTCH4 CRB2

2.09e-05281104PF12661
DomainLaminin_G

LAMA3 NELL1 THBS1 CNTNAP4 CRB2

2.31e-05581105IPR001791
DomainResistin

RETN RETNLB

3.44e-0521102PF06954
DomainResistin

RETN RETNLB

3.44e-0521102IPR009714
DomainPlexin_repeat

PLXDC1 PLXND1 MEGF8 PLXNB3

3.61e-05321104IPR002165
DomainPSI

PLXDC1 PLXND1 MEGF8 PLXNB3

3.61e-05321104PF01437
DomainEGF_dom

NELL1 MEGF8 UMOD

4.21e-05121103IPR024731
DomainEGF_3

NELL1 MEGF8 UMOD

4.21e-05121103PF12947
DomainZnf_RING_CS

RNF31 CBLC TRIM33 TRIM17 ARIH2 SHPRH TRIM60

5.08e-051631107IPR017907
DomainEGF_Lam

LAMA3 MEGF8 MEGF9 PEAR1

5.18e-05351104SM00180
DomainLaminin_EGF

LAMA3 MEGF8 MEGF9 PEAR1

5.18e-05351104PF00053
DomainUnchr_dom_Cys-rich

VWF KCP SSPOP

5.45e-05131103IPR014853
DomainC8

VWF KCP SSPOP

5.45e-05131103SM00832
DomainZF_RING_1

RNF31 CBLC TRIM33 TRIM17 ARIH2 NFX1 SHPRH RFPL2 TRIM60

5.61e-052911109PS00518
DomainTIL_dom

VWF KCP SSPOP

6.90e-05141103IPR002919
DomainLaminin_EGF

LAMA3 MEGF8 MEGF9 PEAR1

7.21e-05381104IPR002049
DomainPep_M12B_propep

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

7.99e-05391104PF01562
DomainPeptidase_M12B_N

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

7.99e-05391104IPR002870
DomainLDLR_class-A_CS

SSPOP LRP1B LRP3 CORIN

8.84e-05401104IPR023415
DomainDISINTEGRIN_1

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

8.84e-05401104PS00427
DomainReprolysin

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

8.84e-05401104PF01421
DomainLaminin_G_2

LAMA3 NELL1 CNTNAP4 CRB2

8.84e-05401104PF02210
DomainADAM_MEPRO

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

8.84e-05401104PS50215
DomainDISINTEGRIN_2

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

8.84e-05401104PS50214
DomainPeptidase_M12B

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

8.84e-05401104IPR001590
DomainDisintegrin_dom

ADAM20 ADAMTS8 ADAMTS12 ADAMTS7

9.75e-05411104IPR001762
DomainLIM3_prickle

PRICKLE1 PRICKLE3

1.03e-0431102IPR033727
DomainLIM2_prickle

PRICKLE1 PRICKLE3

1.03e-0431102IPR033726
DomainPET_prickle

PRICKLE1 PRICKLE3

1.03e-0431102IPR033723
DomainVWF_type-D

VWF KCP SSPOP

1.05e-04161103IPR001846
DomainVWFD

VWF KCP SSPOP

1.05e-04161103PS51233
DomainVWD

VWF KCP SSPOP

1.05e-04161103SM00216
DomainVWD

VWF KCP SSPOP

1.05e-04161103PF00094
Domain-

SPOCK1 TG SPOCK3

1.27e-041711034.10.800.10
DomainEMI

SSPOP UMODL1 PEAR1

1.27e-04171103PS51041
DomainThyroglobulin_1

SPOCK1 TG SPOCK3

1.27e-04171103IPR000716
DomainTHYROGLOBULIN_1_1

SPOCK1 TG SPOCK3

1.27e-04171103PS00484
DomainTY

SPOCK1 TG SPOCK3

1.27e-04171103SM00211
DomainTHYROGLOBULIN_1_2

SPOCK1 TG SPOCK3

1.27e-04171103PS51162
DomainThyroglobulin_1

SPOCK1 TG SPOCK3

1.27e-04171103PF00086
DomainLamG

LAMA3 NELL1 CNTNAP4 CRB2

1.29e-04441104SM00282
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7 NOTCH2 NOTCH4

6.26e-0968848M27303
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

1.04e-0739846M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

1.04e-0739846MM15165
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7 NOTCH2 NOTCH4

2.10e-06143848M27275
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5C KDM3B PHF2 KDM4B

2.49e-0529844MM14934
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

4.64e-05109846MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

5.14e-05111846M27416
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH2 NOTCH4

5.59e-0513843M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NFX1 NOTCH2 NOTCH4

5.59e-0513843M47534
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

WNT1 WNT9A WNT9B JAG2 NOTCH2 NOTCH4

7.23e-05118846M39852
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KMT2B KDM5C NSD1 KDM3B NSD3 PHF2 KDM4B

8.17e-05175847MM14941
PathwayREACTOME_DISEASES_OF_METABOLISM

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7 NOTCH2 NOTCH4

1.19e-04250848M27554
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_ACYLATION

WNT1 WNT9A WNT9B

1.85e-0419843M47836
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KMT2B KDM5C NSD1 KDM3B NSD3 PHF2 KMT2C KDM4B

2.13e-04272848M29619
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5C KDM3B PHF2 KDM4B

2.19e-0450844M27232
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH2 NOTCH4

3.47e-045842M27411
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

WNT1 WNT9A WNT9B JAG2 NOTCH2 NOTCH4

3.94e-04161846M39770
PathwayPID_NOTCH_PATHWAY

SSPOP JAG2 NOTCH2 NOTCH4

4.16e-0459844M17
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT1 WNT9A WNT9B

4.27e-0425843MM14940
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 TLE1 NOTCH2 NOTCH4

4.73e-0461844M39540
PathwayREACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING

WNT1 WNT9A WNT9B

4.81e-0426843M27239
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH2 NOTCH4

5.18e-046842M27068
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 NOTCH2 NOTCH4

5.38e-0427843M39545
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_WNT_INHIBITOR

WNT1 WNT9A WNT9B

6.00e-0428843M47835
PathwayWP_HISTONE_MODIFICATIONS

KMT2B NSD1 EZH1 KMT2C

6.02e-0465844M39374
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PTCH1_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT1 WNT9A WNT9B

6.67e-0429843M47372
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_SMO_TO_HEDGEHOG_SIGNALING_PATHWAY

WNT1 WNT9A WNT9B

6.67e-0429843M47377
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

KMT2B NSD1 NSD3 KMT2C

7.98e-0470844M27231
PathwayKEGG_MEDICUS_VARIANT_FZD7_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

WNT1 WNT9A WNT9B

1.37e-0337843M47411
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 TLE1 NOTCH2 NOTCH4

1.44e-0382844MM15922
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH2 NOTCH4

1.86e-0311842M47865
PathwayBIOCARTA_HES_PATHWAY

WNT1 NOTCH2

2.23e-0312842MM1562
PathwayBIOCARTA_HES_PATHWAY

WNT1 NOTCH2

2.23e-0312842M22042
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH2 NOTCH4

2.23e-0312842M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH2 NOTCH4

2.23e-0312842M47533
PathwayWP_BREAST_CANCER_PATHWAY

ATR WNT1 JAG2 NOTCH2 NOTCH4

2.25e-03154845M39739
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 NOTCH2 NOTCH4

2.42e-0345843M39571
PathwayKEGG_MEDICUS_VARIANT_LRP6_OVEREXPRESSION_TO_WNT_SIGNALING_PATHWAY

WNT1 WNT9A WNT9B

2.42e-0345843M47412
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_PATHWAY

WNT1 WNT9A WNT9B

2.58e-0346843M47409
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH2 NOTCH4

2.58e-0346843MM15971
PathwayREACTOME_PKMTS_METHYLATE_HISTONE_LYSINES

KMT2B NSD1 NSD3

2.58e-0346843MM14933
PathwayPID_PS1_PATHWAY

WNT1 SSPOP TLE1

2.58e-0346843M70
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH2 NOTCH4

2.74e-0347843M7946
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KMT2B KDM5C NSD1 KDM3B EZH1 JMJD1C PHF2 KMT2C KDM4B

6.84e-1449116934368113
Pubmed

New nomenclature for chromatin-modifying enzymes.

KMT2B KDM5C NSD1 KDM3B KMT2C KDM4B

3.82e-0857116618022353
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM5C NSD1 KDM3B EZH1 PHF2

8.33e-0833116526864203
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS8 ADAMTSL3 SSPOP ADAMTS12 THBS1 ADAMTS7

2.02e-0775116620637190
Pubmed

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.

KMT2B KDM5C KDM3B KMT2C KDM4B

3.70e-0744116524183668
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

PRICKLE1 WNT1 WNT9A WNT9B PRICKLE3

5.19e-0747116533141892
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KMT2B KDM5C KMT2C KDM4B

6.73e-0721116427626377
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

KMT2B NSD1 KDM3B CBLC TTYH3 PLXND1 NSD3 JAG2 KMT2C SCAP MEGF8 ADAMTS7 NFX1 LRP3 CENPV NOTCH2

8.57e-0711051161635748872
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

GATA5 JAG2 NOTCH2 NOTCH4

9.91e-0723116414701881
Pubmed

Human ligands of the Notch receptor.

JAG2 NOTCH2 NOTCH4

1.25e-067116310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 NOTCH2 NOTCH4

1.25e-067116312846471
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 NOTCH2 NOTCH4

2.00e-06811639858718
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

VWF RNF31 CRIM1 JAG2 NELL1 MEGF8

2.94e-06118116621078624
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 NOTCH2 NOTCH4

2.99e-069116311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 NOTCH2 NOTCH4

2.99e-069116316245338
Pubmed

Expression of all Wnt genes and their secreted antagonists during mouse blastocyst and postimplantation development.

WNT1 WNT9A WNT9B DKK3

3.01e-0630116415880404
Pubmed

Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development.

WNT1 WNT9A WNT9B TLE1

3.01e-0630116436305473
Pubmed

A mouse knockout library for secreted and transmembrane proteins.

CRIM1 WNT9B SIGLEC5 ADAMTS12 RETN MEGF9 RETNLB SLURP2 NXPH4 DKK3

3.48e-064601161020562862
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 NOTCH2 NOTCH4

4.26e-0610116323665443
Pubmed

Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation.

WNT1 WNT9A WNT9B DKK3

5.68e-0635116419185060
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH2 NOTCH4

5.85e-0611116316607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

TLE1 NOTCH2 NOTCH4

5.85e-0611116315499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 NOTCH2 NOTCH4

5.85e-0611116310878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 NOTCH2 NOTCH4

5.85e-0611116312866128
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

ZSWIM8 KMT2B RNF31 SSPOP PDLIM5 JAG2 NELL1 MEGF8 FHL2 FHL5 DKK3

6.39e-066081161116713569
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

TCF19 KDM5C ISL2 GATA5 EZH1 PHF1 PHF2 PRICKLE3 TLE1 NFX1 FHL2 FHL5 KDM4B

7.69e-068771161320211142
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 NOTCH2 NOTCH4

7.78e-0612116315465494
Pubmed

Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis.

KMT2B KMT2C KDM4B

1.01e-0513116321502505
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 NOTCH2 NOTCH4

1.01e-0513116311578869
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

VWF NOTCH2 NOTCH4

1.01e-0513116320558824
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KMT2B KDM5C KMT2C

1.01e-0513116324619213
Pubmed

Notch receptors and hematopoiesis.

NOTCH2 NOTCH4

1.10e-052116211532344
Pubmed

KMT2B promotes SHPRH expression to regulate 131I sensitivity in thyroid carcinoma cells by affecting FYN protein stability.

KMT2B SHPRH

1.10e-052116234606908
Pubmed

Association of CD40 and thyroglobulin genes with later-onset Graves' disease in Taiwanese patients.

TG CD40

1.10e-052116218755875
Pubmed

Disulfide-dependent multimeric assembly of resistin family hormones.

RETN RETNLB

1.10e-052116215155948
Pubmed

The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis.

ADAMTS12 ADAMTS7

1.10e-052116219098927
Pubmed

Early diagnosis of necrotizing enterocolitis by plasma RELMβ and thrombocytopenia in preterm infants: A pilot study.

RETN RETNLB

1.10e-052116230799148
Pubmed

Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice.

VWF THBS1

1.10e-052116214981081
Pubmed

Representational difference analysis using myeloid cells from C/EBP epsilon deletional mice.

RETN RETNLB

1.10e-052116211090083
Pubmed

HOIL-1L interacting protein (HOIP) is essential for CD40 signaling.

RNF31 CD40

1.10e-052116221829693
Pubmed

ADAMTS7 and ZC3HC1 Share Genetic Predisposition to Coronary Artery Disease and Large Artery Ischemic Stroke.

ZC3HC1 ADAMTS7

1.10e-052116231679296
Pubmed

Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin.

RETN RETNLB

1.10e-052116231101494
Pubmed

Dimerization of resistin and resistin-like molecules is determined by a single cysteine.

RETN RETNLB

1.10e-052116211358969
Pubmed

Thrombospondin 1 requires von Willebrand factor to modulate arterial thrombosis in mice.

VWF THBS1

1.10e-052116225343959
Pubmed

FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family.

RETN RETNLB

1.10e-052116210921885
Pubmed

Relationship between thrombospondin gene variations, von Willebrand factor levels and the risk of coronary heart disease in an older population.

VWF THBS1

1.10e-052116221518247
Pubmed

Thrombospondin-1 in von Willebrand factor function.

VWF THBS1

1.10e-052116218855616
Pubmed

Neurexin Superfamily Cell Membrane Receptor Contactin-Associated Protein Like-4 (Cntnap4) Is Involved in Neural EGFL-Like 1 (Nell-1)-Responsive Osteogenesis.

NELL1 CNTNAP4

1.10e-052116229905970
Pubmed

Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype "Acral FibroChondroMyxoid Tumors".

THBS1 ADGRF5

1.10e-052116232047233
Pubmed

Resistin and RELM-alpha gene expression in white adipose tissue of lactating mice.

RETN RETNLB

1.10e-052116212163041
Pubmed

Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue.

RETN RETNLB

1.10e-052116212145345
Pubmed

Overexpression of Uromodulin-like1 accelerates follicle depletion and subsequent ovarian degeneration.

UMODL1 UMOD

1.10e-052116223190605
Pubmed

Notch4 and Wnt-1 proteins function to regulate branching morphogenesis of mammary epithelial cells in an opposing fashion.

WNT1 NOTCH4

1.10e-05211629576833
Pubmed

notch2, notch4 gene polymorphisms in psoriasis vulgaris.

NOTCH2 NOTCH4

1.10e-052116223587900
Pubmed

Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction.

NOTCH2 NOTCH4

1.10e-052116220643108
Pubmed

Negative effects of ADAMTS-7 and ADAMTS-12 on endplate cartilage differentiation.

ADAMTS12 ADAMTS7

1.10e-052116222247065
Pubmed

Notch signaling in kidney development.

JAG2 NOTCH2

1.10e-052116212496659
Pubmed

Cell-fate transition and determination analysis of mouse male germ cells throughout development.

ATR NOTCH2 NOTCH4

1.28e-0514116334824237
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 NOTCH2 NOTCH4

1.28e-0514116314757642
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

KMT2B KDM5C KDM3B PHF1 PHF2 KDM4B

1.52e-05157116630186101
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 NOTCH2 NOTCH4

1.60e-0515116312971992
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

JAG2 TLE1 NOTCH2

1.60e-051511639291577
Pubmed

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis.

WNT1 WNT9A WNT9B DKK3

1.88e-0547116428813421
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

JAG2 NOTCH2 NOTCH4

1.96e-0516116312617809
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

JAG2 NOTCH2 NOTCH4

1.96e-0516116317273555
Pubmed

Notch gene expression during pancreatic organogenesis.

JAG2 NOTCH2 NOTCH4

1.96e-0516116310842072
Pubmed

Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells.

WNT1 WNT9A WNT9B DKK3

2.22e-0549116419562671
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

JAG2 NOTCH2 NOTCH4

2.38e-0517116318694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

JAG2 NOTCH2 NOTCH4

2.38e-0517116315821257
Pubmed

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

WNT1 WNT9A WNT9B

2.38e-0517116328733458
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

RNF31 PDLIM5 LIMS2 PHF1 KMT2C LDB3 PRICKLE3 NFX1 FHL2 RFPL2 KDM4B

2.65e-057091161122988430
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

JAG2 NOTCH2 NOTCH4

2.84e-0518116318093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

JAG2 NOTCH2 NOTCH4

2.84e-0518116315689374
Pubmed

Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis.

KMT2B WNT1 NSD1 NOTCH2

3.03e-0553116424982181
Pubmed

The NSD family of protein methyltransferases in human cancer.

NSD1 NSD3

3.30e-053116225942451
Pubmed

SPOCK: Master regulator of malignant tumors (Review).

SPOCK1 SPOCK3

3.30e-053116239392048
Pubmed

Association between variations in coagulation system genes and carotid plaque.

VWF THBS1

3.30e-053116222982001
Pubmed

Thrombospondin-1 and ADAMTS13 competitively bind to VWF A2 and A3 domains in vitro.

VWF THBS1

3.30e-053116220705333
Pubmed

Differential expression of Notch genes in human osteoblastic cells.

NOTCH2 NOTCH4

3.30e-053116211836628
Pubmed

Clonal variations among multiple primary mammary tumors and within a tumor of individual mice: insertion mutations of int oncogenes.

WNT1 NOTCH4

3.30e-05311627571419
Pubmed

Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.

NOTCH2 NOTCH4

3.30e-053116211823422
Pubmed

Notch signaling: cell fate control and signal integration in development.

NOTCH2 NOTCH4

3.30e-053116210221902
Pubmed

Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.

JAG2 NOTCH2

3.30e-053116228572448
Pubmed

Found in inflammatory zone 1 induces angiogenesis in murine models of asthma.

VWF RETNLB

3.30e-053116218758859
Pubmed

Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance.

JMJD1C NSD3

3.30e-053116220530532
Pubmed

A family of tissue-specific resistin-like molecules.

RETN RETNLB

3.30e-053116211209052
Pubmed

ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodeling through cleavage of thrombospondin-1.

THBS1 ADAMTS7

3.30e-053116225712208
Pubmed

Notch signaling drives multiple myeloma induced osteoclastogenesis.

JAG2 NOTCH2

3.30e-053116225257302
Pubmed

Evaluating von Willebrand factor and ADAMTS13 levels in thalassemia major patients and assessing a possible association with Thrombospondin-1.

VWF THBS1

3.30e-053116237438087
Pubmed

P-selectin can promote thrombus propagation independently of both von Willebrand factor and thrombospondin-1 in mice.

VWF THBS1

3.30e-053116227943541
Pubmed

Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.

JAG2 NOTCH2

3.30e-053116218458347
Pubmed

Identification of murine and human XCP1 genes as C/EBP-epsilon-dependent members of FIZZ/Resistin gene family.

RETN RETNLB

3.30e-053116215064728
Pubmed

The role of NSD1, NSD2, and NSD3 histone methyltransferases in solid tumors.

NSD1 NSD3

3.30e-053116235532818
Pubmed

The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model.

JAG2 NOTCH2

3.30e-053116237330998
Pubmed

Endothelial CD40 Mediates Microvascular von Willebrand Factor-Dependent Platelet Adhesion Inducing Inflammatory Venothrombosis in ADAMTS13 Knockout Mice.

VWF CD40

3.30e-053116232135568
Pubmed

Coronary Artery Formation Is Driven by Localized Expression of R-spondin3.

WNT1 WNT9A WNT9B

3.37e-0519116328834739
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

JAG2 NOTCH2 NOTCH4

3.37e-0519116316518823
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

JAG2 NOTCH2 NOTCH4

4.60e-0521116328656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

JAG2 NOTCH2 NOTCH4

4.60e-0521116314702043
Pubmed

Epithelial Wnt10a Is Essential for Tooth Root Furcation Morphogenesis.

WNT1 WNT9A WNT9B

4.60e-0521116331914354
InteractionGFI1B interactions

RNF31 KDM3B PDLIM5 JAG2 NELL1 MEGF8 TLE1 KDM4B

8.04e-071361108int:GFI1B
InteractionATN1 interactions

ZSWIM8 KMT2B RNF31 SSPOP JAG2 NELL1 KMT2C MEGF8 TLE1

8.72e-071871109int:ATN1
InteractionHOXA1 interactions

VWF TCF19 LIMS2 JAG2 NELL1 MEGF8 TLE1 VWC2L KRTAP11-1 FHL5 DKK3

4.01e-0635611011int:HOXA1
InteractionINHBE interactions

SCAP ADAMTS7 LY6H DKK3 NOTCH2

4.54e-06451105int:INHBE
InteractionTIMP3 interactions

LRP1B NELL1 ADAMTS7 LY6H DKK3 NOTCH2

9.89e-06901106int:TIMP3
InteractionEMILIN2 interactions

NELL1 RETNLB LRP3 NOTCH2

1.34e-05271104int:EMILIN2
InteractionATXN7 interactions

VWF RNF31 CRIM1 JAG2 NELL1 MEGF8

2.96e-051091106int:ATXN7
InteractionIGFL3 interactions

LAMA3 LRP1B JAG2 ADAMTS7 NOTCH2

5.63e-05751105int:IGFL3
Cytoband4q32.3

TRIM75 SPOCK3 TRIM60

8.88e-053411634q32.3
GeneFamilyPHD finger proteins

KMT2B TCF19 KDM5C NSD1 NSD3 PHF1 PHF2 TRIM33 KMT2C PYGO2 NFX1 SHPRH

2.59e-1590761288
GeneFamilyLIM domain containing

PRICKLE1 PDLIM5 LIMK2 LDB3 PRICKLE3 FHL2 FHL5

5.01e-09597671218
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5C KDM3B JMJD1C PHF2 KDM4B

4.59e-0824765485
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2B NSD1 EZH1 NSD3 KMT2C

2.91e-0734765487
GeneFamilyRing finger proteins

RNF31 TRIM75 CBLC TRIM33 TRIM17 SHPRH RFPL2 TRIM60

1.99e-0527576858
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS8 ADAMTS12 ADAMTS7

6.59e-051976350
GeneFamilyWnt family|Endogenous ligands

WNT1 WNT9A WNT9B

6.59e-0519763360
GeneFamilyPrickle planar cell polarity proteins|LIM domain containing

PRICKLE1 PRICKLE3

1.04e-0447621184
GeneFamilySPARC family

SPOCK1 SPOCK3

4.80e-0487621278
GeneFamilyPlexins

PLXND1 PLXNB3

6.16e-049762683
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM75 TRIM33 TRIM17 TRIM60

6.87e-049576459
GeneFamilyLow density lipoprotein receptors

LRP1B LRP3

1.32e-0313762634
GeneFamilyPWWP domain containing

NSD1 NSD3

3.81e-03227621147
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC1 ZDHHC23

4.53e-032476276
GeneFamilyTudor domain containing

PHF1 KDM4B

1.06e-0237762780
CoexpressionNABA_MATRISOME

VWF CRIM1 PLXDC1 SPOCK1 IL37 ADAM20 WNT1 WNT9A WNT9B KCP LAMA3 ADAMTS8 PLXND1 ADAMTSL3 SSPOP ADAMTS12 NELL1 THBS1 TINAG MEGF8 MEGF9 ADAMTS7 SPOCK3 VWC2L SERPINC1 PLXNB3

2.38e-13102611426M5889
CoexpressionNABA_MATRISOME

VWF CRIM1 PLXDC1 SPOCK1 ADAM20 WNT1 WNT9A WNT9B KCP LAMA3 ADAMTS8 PLXND1 ADAMTSL3 SSPOP ADAMTS12 NELL1 THBS1 TINAG MEGF8 MEGF9 ADAMTS7 SPOCK3 VWC2L SERPINC1 PLXNB3

1.19e-12100811425MM17056
CoexpressionNABA_MATRISOME_ASSOCIATED

PLXDC1 IL37 ADAM20 WNT1 WNT9A WNT9B ADAMTS8 PLXND1 ADAMTSL3 ADAMTS12 MEGF8 MEGF9 ADAMTS7 VWC2L SERPINC1 PLXNB3

1.67e-0775111416M5885
CoexpressionNABA_CORE_MATRISOME

VWF CRIM1 SPOCK1 KCP LAMA3 SSPOP NELL1 THBS1 TINAG SPOCK3

3.03e-0727011410MM17057
CoexpressionNABA_CORE_MATRISOME

VWF CRIM1 SPOCK1 KCP LAMA3 SSPOP NELL1 THBS1 TINAG SPOCK3

3.58e-0727511410M5884
CoexpressionNABA_MATRISOME_ASSOCIATED

PLXDC1 ADAM20 WNT1 WNT9A WNT9B ADAMTS8 PLXND1 ADAMTSL3 ADAMTS12 MEGF8 MEGF9 ADAMTS7 VWC2L SERPINC1 PLXNB3

7.57e-0773811415MM17058
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF CRIM1 KCP LAMA3 SSPOP NELL1 THBS1 TINAG

1.95e-061911148MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF CRIM1 KCP LAMA3 SSPOP NELL1 THBS1 TINAG

2.37e-061961148M3008
CoexpressionSCHERER_PBMC_APSV_WETVAX_AGE_18_40YO_5_TO_7DY_UP

LIMK2 CD40 NFX1 C3AR1

3.37e-06241144M41045
CoexpressionSAMOLS_TARGETS_OF_KHSV_MIRNAS_DN

THBS1 SPOCK3 FHL2 NXPH4 DKK3

6.43e-06601145M17268
CoexpressionINAMURA_LUNG_CANCER_SCC_DN

VWF ADAMTS8 ADAMTSL3

2.22e-05131143M1255
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_PERICYTE

PLXDC1 KCP ADAMTSL3 PDLIM5 ADGRF5 FHL5 PEAR1

2.38e-051951147M45684
CoexpressionGSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP

KDM3B PHF2 LIMK2 SCAP MEGF9 ARIH2 NOTCH2

2.54e-051971147M5351
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH2 NOTCH4

4.31e-05161143MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH2 NOTCH4

4.31e-05161143M2207
CoexpressionDESCARTES_FETAL_EYE_VASCULAR_ENDOTHELIAL_CELLS

VWF PLXND1 ADORA2A-AS1 ADGRF5 NOTCH4

5.18e-05921145M40189
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP

PLXDC1 WNT1 JAG2 SERPINC1 NOTCH2 NOTCH4

8.08e-051631146M12112
CoexpressionGSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN

KMT2B CRIM1 SIGLEC5 NSD3 CLDND2 NOTCH2

8.94e-051661146M6701
CoexpressionMAHADEVAN_IMATINIB_RESISTANCE_UP

CRIM1 SPOCK1 DKK3

1.16e-04221143M18876
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

CRIM1 KCP ADAMTSL3 LDB3 TLE1 UMOD FHL2 FHL5 PEAR1

1.31e-091831169fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWF CRIM1 PLXND1 LIMS2 JAG2 ADAMTS7 ADGRF5 NOTCH4 PEAR1

2.74e-091991169463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CRIM1 PLXDC1 KCP ADAMTS8 ADAMTSL3 PDLIM5 LDB3 FHL5 DKK3

2.86e-0920011694e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LAMA3 TTYH3 LRP1B JMJD1C KMT2C THBS1 MEGF9 CNTNAP4

3.18e-08186116823b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VWF LAMA3 PLXND1 LIMS2 JAG2 CNTNAP4 ADGRF5 NOTCH4

4.07e-08192116856b021c297a21dff357531f21e2464f85186106d
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWF PLXND1 LIMS2 JAG2 ADAMTS7 ADGRF5 NOTCH4 PEAR1

4.97e-081971168a312d9cf4ced949307eb9620be4eed926300b892
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS8 PDLIM5 LIMS2 THBS1 LDB3 FHL2 FHL5 DKK3

5.17e-081981168c82a151f9f1477d4a401457173b8d72af776c137
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS8 PDLIM5 LIMS2 THBS1 LDB3 FHL2 FHL5 DKK3

5.17e-081981168dc63b56bb6291e527b172d603569376286262845
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

CRIM1 PLXDC1 KCP ADAMTS8 ADAMTSL3 ADAMTS12 DKK3 NOTCH2

5.58e-082001168bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCelldroplet-Heart-4Chambers-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 PLXND1 LIMS2 CLDND2 ADGRF5 NOTCH4

3.61e-0717311679a04271c51fae34f547db3206f9ff5857686e45c
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

VWF PLXND1 LIMS2 JAG2 CD40 ADGRF5 NOTCH4

4.71e-0718011675861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellCOVID-19-Heart-EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

VWF PLXDC1 ADAMTSL3 LIMS2 ADAMTS12 FHL5 NOTCH4

5.08e-071821167e67f3234165199085c793915ebb1f9bbd845e933
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

PLXDC1 ADAMTSL3 ADAMTS12 ADORA2A-AS1 TLE1 FHL5 PEAR1

5.27e-071831167273db6a3b00a93ca852498471187b642b5368185
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 PRICKLE1 LAMA3 THBS1 TENM3 FHL2 CRB2

6.32e-071881167b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 PRICKLE1 LAMA3 THBS1 TENM3 FHL2 CRB2

6.32e-071881167874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VWF PDLIM5 LIMS2 JAG2 TLE1 CNTNAP4 NOTCH4

6.54e-071891167c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellIPF-Stromal-Pericyte|World / Disease state, Lineage and Cell class

PLXDC1 ADAMTSL3 LDB3 ADGRF5 FHL5 DKK3 PEAR1

7.80e-0719411671a41da29d5adaf766a84eff0003b959e4523f7f1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF LAMA3 PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

8.07e-0719511676bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellIPF-Stromal-Pericyte|IPF / Disease state, Lineage and Cell class

PLXDC1 ADAMTSL3 LDB3 ADGRF5 FHL5 DKK3 PEAR1

8.35e-0719611678b6ff47ce5291d223f5e639fc45cd9267f418256
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRIM1 ADAMTS8 ADAMTSL3 LDB3 FHL5 DKK3 PEAR1

8.64e-07197116701249bd485a3734de87ae6ed9c749597f39c6335
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWF CRIM1 PLXND1 JAG2 ADGRF5 NOTCH4 PEAR1

8.94e-071981167e1fa02184ce93c4f8aa5cf04b70949cd4c425ff0
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA3 ADAMTS12 LDB3 ADGRF5 FHL2 FHL5 PEAR1

8.94e-071981167b7e900fc0a1b3fa5e47dcc36ce6b0c3ce6bf9739
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 THBS1 LIMK2 TENM3 FHL2 DKK3 CRB2

9.24e-071991167b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CRIM1 THBS1 LIMK2 TENM3 FHL2 DKK3 CRB2

9.24e-071991167c972d3036151403f26fa9d6271520639c281ab84
ToppCellILEUM-inflamed-(7)_Endothelial_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

VWF CRIM1 PLXND1 JAG2 NELL1 ADGRF5 NOTCH4

9.24e-07199116797052c28e354833901f28d339b09f97f50a5b752
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4 PEAR1

9.24e-0719911670602e2b2aa56d106da63bd342a38bef437b4d496
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CRIM1 PLXDC1 KCP ADAMTSL3 LDB3 FHL5 DKK3

9.56e-072001167b5b5a32925f225610fe25a021a742d6397162863
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CRIM1 PLXDC1 KCP ADAMTS8 ADAMTSL3 FHL5 DKK3

9.56e-072001167cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellTracheal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLXDC1 PLXND1 ADAMTS12 LDB3 ADGRF5 FHL5 PEAR1

9.56e-0720011679d3ae9ea47b1017adb63aa02d10e98193d478458
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TCF19 KCP CBLC ZDHHC1 LIMS2 PLXNB3

1.75e-0613911662fb51abb3ce88c21726c026d6365b2582e2e79f6
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXDC1 SPOCK1 ADAMTSL3 LCMT2 NELL1 KCNMB3

3.55e-061571166f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCF19 PLXDC1 WNT9A PLXND1 ZDHHC23 VWC2L

3.68e-061581166c8af8964a140acb2987e3b4906d72c546108d229
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

VWF PLXND1 LIMS2 PLA2G2D ADGRF5 NOTCH4

3.96e-0616011660d4880f85565d8c540c94a8f8109147b3029279a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF LAMA3 LIMS2 JAG2 ADGRF5 NOTCH4

4.89e-0616611668e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D122|Adult / Lineage, Cell type, age group and donor

VWF WNT9B LIMS2 JAG2 NOTCH4 PEAR1

5.24e-0616811668c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VWF LIMS2 JAG2 LIMK2 ADGRF5 NOTCH4

5.42e-061691166c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellAT1_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

WNT9A LAMA3 LIMS2 MEGF9 ZDHHC23 TRIM17

6.20e-061731166b29816427428c7053017477f59b828bf1357f3b2
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMS2 RETN TENM3 CNTNAP4 ADGRF5 LY6H

6.84e-06176116627e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SEH1L KCP TTYH3 KMT2C NFX1 NOTCH4

7.06e-061771166eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SEH1L KCP TTYH3 TRIM33 NFX1 NOTCH4

7.29e-0617811669d575902d3dbe33437c9d4200df093a741269803
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

SEH1L KCP TTYH3 TRIM33 KMT2C NFX1

7.29e-061781166536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCell3'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EZH1 LIMS2 JAG2 ADORA2A-AS1 CORIN NOTCH4

7.29e-061781166c30d3390fc4a7856f50ba8ff6694c0333165ddde
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 PLXDC1 ADAMTSL3 LDB3 NXPH4 DKK3

7.53e-061791166bfc226bcf0b93525992344f968268a261d86fcbf
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VWF PLXND1 LIMS2 ADAMTS7 ADGRF5 NOTCH4

7.53e-0617911668f9e538c822940785130297712b75131812a4603
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

VWF WNT9A PLXND1 LIMS2 JAG2 SLURP2

7.53e-061791166040a7e916baaf81f44339dc721ab2afcd2c22388
ToppCelldroplet-Lung-LUNG-30m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 PLXDC1 ADAMTSL3 LDB3 NXPH4 DKK3

7.53e-06179116636ad18f52e175ab636ceaa3be81212fa362c96c1
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 JAG2 CD40 ADGRF5 NOTCH4

8.02e-0618111669bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCellnormal_Lung-Fibroblasts-Pericytes|normal_Lung / Location, Cell class and cell subclass

CRIM1 PLXDC1 ADAMTSL3 FHL5 DKK3 PEAR1

8.02e-061811166f74941e49950027360d71ea3b205fc20c6929766
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 JAG2 CD40 ADGRF5 NOTCH4

8.02e-0618111667d7d1edeae4e0ebe40b324d1231cd26e27ba9d42
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|metastatic_Brain / Location, Cell class and cell subclass

SPOCK1 ADAMTSL3 ADAMTS12 TENM3 CORIN DKK3

8.02e-061811166bd0b5f74f9c81ec0f1592710774a4fdf33d9d5a9
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 PLXND1 ADGRF5 DKK3 NOTCH4 PEAR1

8.28e-061821166dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

8.28e-0618211660639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 JAG2 CD40 ADGRF5 NOTCH4

8.28e-0618211660346f81bbb1f309f3e9d063b20547d548d09472c
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE1 PLXND1 ADGRF5 DKK3 NOTCH4 PEAR1

8.28e-061821166010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

ADAMTSL3 ADAMTS12 TLE1 ADGRF5 FHL5 PEAR1

8.54e-061831166e3835db4795362b0442d5893baf2a78efcc20428
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CRIM1 PLXDC1 KCP ADAMTSL3 FHL5 DKK3

8.54e-0618311668a799807fbf24456a9811e0c64068187940a2f71
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PRICKLE1 PDLIM5 THBS1 FHL2 PLXNB3 PEAR1

8.54e-0618311666cbc88c27dc957d182526e84824f70c8e860bf74
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VWF TCF19 PLXND1 LIMS2 ADGRF5 NOTCH4

8.81e-061841166688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell5'-GW_trimst-2-LymphNode-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 LIMS2 CD40 ADGRF5 NOTCH4

8.81e-061841166df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

8.81e-061841166842473fa415575441b595073a994b6d621169776
ToppCell5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 LIMS2 CD40 ADGRF5 NOTCH4

8.81e-0618411661ace70f12b417185bdd46042833f72b3b6815966
ToppCelldroplet-Fat-Mat-18m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 ADAMTS8 LIMS2 NFX1 ADGRF5

9.09e-061851166d9be5853acdda7b1ac819cf50c7940d1d2362d15
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

CRIM1 PLXDC1 ADAMTSL3 LDB3 ADGRF5 FHL5

9.09e-0618511664905adaeeffd353e089578e5ea614437dbe794e6
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF TTYH3 PLXND1 JAG2 ADGRF5 NOTCH4

9.09e-061851166602536a3308a848f106adcb0a83530997440c8f4
ToppCelldroplet-Bladder-nan-24m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF ADAMTS8 PLXND1 LIMS2 LDB3 ADGRF5

9.09e-06185116690caab8d9361a541c5d5121c97c3f1cdffeeae4a
ToppCellControl-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

PLXDC1 TG SPOCK3 FHL2 DKK3 NOTCH4

9.09e-061851166d5d6d13e2f20b54ca55645b9a757b8599f4fd897
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

PLXDC1 ADAMTSL3 ADAMTS12 TLE1 FHL5 PEAR1

9.09e-061851166acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

VWF LAMA3 PLXND1 JAG2 ADGRF5 NOTCH4

9.37e-061861166a844d4f79e0ad5d6c60a4488ffd8f4f21b7eed04
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 PLXDC1 KCP ADAMTSL3 ADGRF5 FHL5

9.66e-061871166fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

CRIM1 KCP ADAMTSL3 LDB3 FHL5 PEAR1

9.66e-06187116662759efb660179402fb574ce5701c89a2e17bcfe
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

VWF LIMS2 JAG2 CD40 ADGRF5 NOTCH4

9.66e-06187116629b2e2be26a9d72b154760e47acf61cfe2f45fa7
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

PLXND1 ADAMTSL3 ADAMTS12 ADGRF5 FHL5 PEAR1

9.66e-061871166dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-8|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMS2 ZDHHC23 TLE1 CD40 NXPH4 KDM4B

9.66e-061871166c10d6a774b3e83f64e47b9ad08f5d6b0dc60d163
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 JAG2 CD40 ADGRF5 NOTCH4

9.66e-06187116625efb82afe863a853ecdd781ad89026c993aaa67
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

VWF PLXND1 LIMS2 JAG2 CD40 ADGRF5

9.66e-06187116603de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

9.66e-061871166a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CRIM1 PLXDC1 KCP ADAMTSL3 FHL5 PEAR1

9.96e-061881166ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellnormal_Lung-Fibroblasts-Smooth_muscle_cells|normal_Lung / Location, Cell class and cell subclass

CRIM1 ADAMTS8 LDB3 FHL2 FHL5 DKK3

9.96e-061881166fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 JAG2 CD40 ADGRF5 NOTCH4

9.96e-0618811665d166d9e71632edd059ff0a9f66f8763f259d40a
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 PLXND1 LIMS2 ADGRF5 NOTCH4

9.96e-06188116605de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

9.96e-061881166a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 JAG2 CD40 ADGRF5 NOTCH4

1.03e-0518911669e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 PLXND1 LIMS2 ADGRF5 NOTCH4

1.03e-0518911668ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PRICKLE1 ADAMTS8 LIMS2 LDB3 SPOCK3 FHL2

1.03e-051891166da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 JAG2 CD40 ADGRF5 NOTCH4

1.03e-051891166a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 PLXND1 LIMS2 ADGRF5 NOTCH4

1.03e-051891166403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

1.06e-051901166bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 PRICKLE1 PLXND1 ADGRF5 DKK3 NOTCH4

1.06e-051901166a08c5929b05a4969852e351a93c4e4deb4c8d5b6
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 LAMA3 LIMS2 THBS1 ADGRF5

1.06e-0519011669d5242759546be0089981ef1877e4ed5f81face5
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 LAMA3 PLXND1 LIMS2 ADGRF5 NOTCH4

1.06e-051901166b7fc451e160e31dc898b122de844b501f587db67
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VWF PLXND1 LIMS2 JAG2 CNTNAP4 NOTCH4

1.06e-051901166aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 LIMS2 JAG2 ADGRF5 NOTCH4

1.06e-05190116638a815abf0ac5cac6071737cadc54a514f62d37d
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

1.06e-0519011661519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCelldroplet-Liver-LIVER_NPC-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 PRICKLE1 PLXND1 ADGRF5 DKK3 NOTCH4

1.06e-05190116625525fee1da8a808034d9c916159fd0b6b26bce8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLXDC1 PDLIM5 ADAMTS12 LDB3 TENM3 FHL5

1.06e-05190116670c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

VWF ADAMTS12 TLE1 ADGRF5 FHL5 NOTCH4

1.06e-051901166a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWF PLXND1 LIMS2 JAG2 ADGRF5 NOTCH4

1.06e-051901166141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 LIMS2 JAG2 ADGRF5 NOTCH4

1.06e-051901166bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF CRIM1 LIMS2 JAG2 ADGRF5 NOTCH4

1.06e-051901166d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 LAMA3 PLXND1 LIMS2 ADGRF5 NOTCH4

1.06e-05190116683cc851fb9f644b17a8ebf4d99a646003769a22f
DrugIsocarboxazid [59-63-2]; Down 200; 17.2uM; HL60; HT_HG-U133A

KMT2B KDM5C PDLIM5 LIMS2 THBS1 LIMK2 RETN NOTCH2 KDM4B

6.77e-0719911392562_DN
DrugICI182,780; Up 200; 1uM; PC3; HT_HG-U133A

CBLC PDLIM5 THBS1 MEGF8 CD40 NFX1 ZNF74 KDM4B

6.42e-0619711386867_UP
Diseasecortical thickness

KMT2B CRIM1 ZC3HC1 ADAMTS8 PLXND1 ADAMTSL3 JMJD1C TG JAG2 NELL1 THBS1 MEGF9 ADAMTS7 UMODL1 KDM4B CRB2

3.34e-06111310916EFO_0004840
Diseaseobesity (implicated_via_orthology)

WNT1 ADAMTS8 PLXND1 CD40 NOTCH2 PLXNB3 NOTCH4

1.57e-052151097DOID:9970 (implicated_via_orthology)
DiseaseSotos syndrome 1 (implicated_via_orthology)

NSD1 NSD3

4.05e-0531092DOID:0112103 (implicated_via_orthology)
DiseaseCerebral Thrombosis

VWF SERPINC1

4.05e-0531092C0079102
DiseaseBrain Thrombus

VWF SERPINC1

4.05e-0531092C0936261
DiseaseCerebral Thrombus

VWF SERPINC1

4.05e-0531092C0936263
DiseaseIntracranial Thrombosis

VWF SERPINC1

4.05e-0531092C0752143
DiseaseBrain Thrombosis

VWF SERPINC1

4.05e-0531092C0752144
Diseasemyofibrillar myopathy 4 (implicated_via_orthology)

PDLIM5 LDB3

4.05e-0531092DOID:0080095 (implicated_via_orthology)
Diseaseosteonecrosis (is_marker_for)

VWF SERPINC1

8.07e-0541092DOID:10159 (is_marker_for)
Diseasechronic hepatitis B virus infection

TCF19 CD40 NOTCH4

9.38e-05241093EFO_0004239
Diseaseadenoid cystic carcinoma (is_implicated_in)

ATR KMT2C

1.34e-0451092DOID:0080202 (is_implicated_in)
Diseasecentral serous retinopathy

GATA5 NOTCH4

3.73e-0481092EFO_0009784
DiseaseLeukemia, Myelocytic, Acute

NSD1 CBLC KMT2C FHL2 NOTCH2

4.67e-041731095C0023467
Diseasechronic central serous retinopathy

GATA5 MEGF9

4.79e-0491092EFO_0009363
DiseasePR interval

PDLIM5 NELL1 THBS1 LDB3 VWC2L KCNMB3 KRTAP11-1 FHL2

5.13e-044951098EFO_0004462
Diseasebreast cancer (is_marker_for)

KMT2B KDM5C WNT9A KDM3B KDM4B

6.33e-041851095DOID:1612 (is_marker_for)
Diseasefolic acid measurement

WNT9A PHF1 PHF2

6.63e-04461093EFO_0005111
Diseaseend stage renal disease (is_marker_for)

VWF RETN CD40

6.63e-04461093DOID:783 (is_marker_for)
Diseasemyopathy (implicated_via_orthology)

PDLIM5 LDB3 PEAR1

7.51e-04481093DOID:423 (implicated_via_orthology)
Diseasedickkopf‐related protein 1 measurement

JMJD1C PEAR1

8.71e-04121092EFO_0010620
Diseasecolitis (implicated_via_orthology)

RETN CD40

1.03e-03131092DOID:0060180 (implicated_via_orthology)
Diseaseatrial fibrillation (is_implicated_in)

VWF GATA5

1.20e-03141092DOID:0060224 (is_implicated_in)
Diseasefemoral neck bone geometry

NSD1 UMOD

1.20e-03141092EFO_0004511
DiseaseProteinuria

VWF ADAMTS7

1.38e-03151092HP_0000093
Diseasepancreatic ductal carcinoma (is_implicated_in)

THBS1 CD40

1.57e-03161092DOID:3587 (is_implicated_in)
Diseasemethylcobalamin deficiency type cblE, brain serotonin transporter measurement

VWF LIMK2

1.57e-03161092EFO_0004569, MONDO_0009354
Diseaseneutrophil count

IL37 KDM5C NSD1 ZC3HC1 JMJD1C JAG2 TRIM33 C3AR1 ADGRF5 NOTCH2 KDM4B NOTCH4 PEAR1

1.77e-03138210913EFO_0004833
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

KMT2B KDM4B

1.77e-03171092DOID:0060307 (is_implicated_in)
Diseasesyndrome (implicated_via_orthology)

NSD1 NSD3

1.99e-03181092DOID:225 (implicated_via_orthology)
Diseasestomach cancer (is_implicated_in)

LRP1B KMT2C KDM4B

2.43e-03721093DOID:10534 (is_implicated_in)
Diseasemigraine disorder, endometriosis

LRP1B NELL1 FHL5

2.53e-03731093EFO_0001065, MONDO_0005277
DiseaseDrugs used in diabetes use measurement

NSD1 JMJD1C SPOCK3 TLE1 NOTCH2

2.61e-032551095EFO_0009924
Diseasestroke, coronary artery disease

ZC3HC1 ADAMTS7

2.71e-03211092EFO_0000712, EFO_0001645
Diseasediaphragmatic hernia

PHF1 PHF2

2.71e-03211092EFO_0008561
DiseaseNephritis, Tubulointerstitial

THBS1 UMOD

2.71e-03211092C0041349
DiseaseRenal glomerular disease

UMOD CRB2

3.25e-03231092C0268731
DiseaseGlomerulopathy Assessment

UMOD CRB2

3.25e-03231092C4521256
DiseaseGraves disease

PRICKLE1 TG CD40

3.39e-03811093EFO_0004237
DiseaseNephritis, Interstitial

THBS1 UMOD

3.54e-03241092C0027707
DiseaseCarcinoma, Pancreatic Ductal

JAG2 NOTCH4

3.54e-03241092C0887833

Protein segments in the cluster

PeptideGeneStartEntry
CVDSAEHDCSPAAWC

UMODL1

511

Q5DID0
CGHLLCSCCLAAWQH

CBLC

366

Q9ULV8
CSCCLAAWQHSDSQT

CBLC

371

Q9ULV8
ECDLPEWCNGTSHQC

ADAM20

471

O43506
TSAQDVCAQLWCHTD

ADAMTS8

466

Q9UP79
CCVAQARVQWCHLGS

CCDC28A-AS1

16

A0A096LPI5
TCQAAIHKVCRWQGC

ADORA2A-AS1

126

P86434
GGECSQSWSTFHCNC

CNTNAP4

561

Q9C0A0
CRSCWEQHCSVLVKD

ARIH2

161

O95376
FWDCVTCHGSPVDIC

SERPINC1

26

P01008
WDHVCIALASANSCF

C3AR1

416

Q16581
RTCCHWGETALFMCN

DEFB132

36

Q7Z7B7
LCCHWATGNWDLCST

ADAMTS12

1471

P58397
VCHTLWCSVGTTCHS

ADAMTS7

491

Q9UKP4
VCFTEHTQSQAAWLC

NXPH4

256

O95158
WHQCDICGKEAASFC

NSD1

2161

Q96L73
ECQWTDACLSHPCAN

NOTCH2NLB

141

P0DPK3
ECQWTDACLSHPCAN

NOTCH2

141

Q04721
DGVCDEACNSHACQW

NOTCH2

1436

Q04721
CCLMVACAWASGSIN

OR2AK2

156

Q8NG84
QWCCHCKVVILGSGV

KMT2C

4196

Q8NEZ4
ALNKAWCVSCFSCST

LIMS2

271

Q7Z4I7
CNNSLCKLHFWVCDG

LRP1B

3681

Q9NZR2
AWEQSHECEACNCHG

LAMA3

346

Q16787
RQTWHTTCFVCAACK

LDB3

626

O75112
LGHTWHDTCFICAVC

LDB3

686

O75112
TCLVTWNDFHCTCPA

CRB2

821

Q5IJ48
ETWHGSCFRCSECQD

LIMK2

31

P53671
QVSCGNWHCLALAAD

HERC3

141

Q15034
HGSSWVEDCNSCRCL

JAG2

881

Q9Y219
ALVCCLLTAWHCRSG

SMPDL3A

6

Q92484
CDACEATLFNIHWVC

JMJD1C

1846

Q15652
SHCQAANRSLGCLWC

PLXNB3

796

Q9ULL4
HTACTSCLSAQWPCF

PLXND1

711

Q9Y4D7
WGFSCNASCQCAHEA

PEAR1

486

Q5VY43
QGCGWCLTSATCHLR

MEGF8

861

Q7Z7M0
CAWCQSTHTCFLFAA

MEGF8

966

Q7Z7M0
TCHECLQSHECGWCG

MEGF8

1011

Q7Z7M0
CNQSGACTWCHGACL

MEGF8

1886

Q7Z7M0
ACTWCHGACLSGDQA

MEGF8

1891

Q7Z7M0
QTCWQASFDELTCHC

NFX1

736

Q12986
CDVCETTLFNIHWVC

KDM3B

1031

Q7LBC6
SRCAAHAWTAECCLC

KDM4B

786

O94953
HCGTNLCIFETWRCD

LRP3

461

O75074
ECINCLHNTTGFWCE

MEGF9

421

Q9H1U4
QCAQCDHWVHAKCEG

KMT2B

1356

Q9UMN6
QTWHVSCFVCVACGK

PDLIM5

496

Q96HC4
TIHCDISSCWCQGSV

MEIOSIN

261

C9JSJ3
WVDGDHCRNCTCKSG

NELL1

286

Q92832
LWCQDCTLTTNSSHC

LY6H

26

O94772
CEASCQKWFHRECTG

PYGO2

346

Q9BRQ0
HWHATEACFSCAQCK

PRICKLE1

271

Q96MT3
WHPQCFVCTTCQELL

PRICKLE3

211

O43900
GCGSWDVQLETTCHC

RETNLB

81

Q9BQ08
TTCHCQCSVVDWTTA

RETNLB

91

Q9BQ08
QCSVVDWTTARCCHL

RETNLB

96

Q9BQ08
LCCTNCHTTNTTLWR

GATA5

241

Q9BWX5
WDCFVRCLDHACLGS

ATR

1196

Q13535
QDSQWHSECFNCGKC

FHL5

241

Q5TD97
AHPGWFICTSCNCNE

IL37

171

Q9NZH6
CSAVWHDTKISCECE

FBXL8

41

Q96CD0
ETTCGLAVCQHPQCW

C9orf43

11

Q8TAL5
VWASADLHIFDCNCS

CENPV

161

Q7Z7K6
ETWNIDSCTQCTCHS

CRIM1

691

Q9NZV1
ECANHACVSRDLWCD

CORIN

661

Q9Y5Q5
WHEACFHCSQCRNSL

FHL2

61

Q14192
WLDCAFTCGVHCHGQ

KCNMB3

106

Q9NPA1
WLLDHCQETCCEPTA

KRTAP11-1

51

Q8IUC1
QHEISCKLSCSCISW

SEH1L

156

Q96EE3
SCCLAGHVCVWDAQT

SCAP

791

Q12770
DSECCGDQLCVWGHC

DKK3

181

Q9UBP4
MGNILTCCINSHCGW

DRICH1

1

Q6PGQ1
LEWHAACLKCAECSQ

ISL2

46

Q96A47
SCLQWFHEACTQCLS

PHF1

206

O43189
SCHSCACGNSNSWDK

MIGA1

176

Q8NAN2
VECGEWLCKTCIEAH

TRIM33

231

Q9UPN9
IECDACKDWFHGSCV

PHF2

21

O75151
GWHCQVVACVEGCFC

SSPOP

1301

A2VEC9
GWVLVEGTGESCCHC

SSPOP

2011

A2VEC9
SQLQHGAALCEWVCV

TMEM150A

201

Q86TG1
VHCCWAFSICQVARE

PLAC8L1

141

A1L4L8
ACHLCLCWEGSVSCE

KCP

746

Q6ZWJ8
SCSWEAEGLHCRCSF

SIGLEC5

341

O15389
KQWAVLTCGHCFCNE

SHPRH

1441

Q149N8
HCQRSSCVCDVGWTG

NOTCH4

671

Q99466
HCSDKGSWCEQQLCA

PLA2G2D

96

Q9UNK4
QLAAAEAIWCHQCTG

SLURP2

16

P0DP57
AALTACTHVQWDCAS

ADGRD2

141

Q7Z7M1
VSWCSKTVDVCCHFT

ADGRF5

631

Q8IZF2
LWQECNHGICSSIPC

CLDND2

41

Q8NHS1
DGCDVWFHVACVGCS

TCF19

311

Q9Y242
IHCTFCNSSPGWVCV

RNF31

416

Q96EP0
VTACILSVCGWACSS

ZC3HC1

246

Q86WB0
SCCSDGNIAVWDLHN

TLE1

591

Q04724
WTVDSCTECHCQNSV

THBS1

331

P07996
WCSECHSNATCTEDE

UMOD

31

P07911
WNCTDHVCDATCSTI

VWF

856

P04275
CGHNFCRSCIQQSWL

TRIM75

31

A6NK02
CLTCGASEHWDCKVV

EZH1

586

Q92800
TQCHGSTGQCWCVDK

SPOCK1

346

Q08629
KCECSQGWNGEHCTI

TENM3

726

Q9P273
SRICLCAVLCGHWDF

RFPL2

16

O75678
GVLCCQGECQWLHLD

SRM

201

P19623
CGHNFCRSCLSVSWK

TRIM60

31

Q495X7
ECPWHQCDECSSAAV

NSD3

1361

Q9BZ95
AVLCVCAAAWCSQSL

SPOCK3

6

Q9BQ16
DHHCVWINSCVGESN

ZDHHC23

286

Q8IYP9
CGHNFCRACIQLSWE

TRIM17

31

Q9Y577
CSCTCGAGAKWCTHV

ZSWIM8

186

A7E2V4
VTERCNCTFHWCCHV

WNT1

341

P04628
WCRCEPSNEVHCVVA

VWC2L

136

B2RUY7
KCHGVSGSCTVRTCW

WNT9A

216

O14904
SWIHCSICNHCAVPD

ZCCHC4

421

Q9H5U6
DCSQCWKAFSCHSSL

ZNF74

501

Q16587
NCSWCHVLQRCSSGF

PLXDC1

321

Q8IUK5
TLCCWRHSTTEVSCQ

LCMT2

476

O60294
TCSGQQWKCSQHVCL

TINAG

141

Q9UJW2
KCHGVSGSCAVRTCW

WNT9B

211

O14905
WDVRAETTCHCQCAG

RETN

81

Q9HD89
ETTCHCQCAGMDWTG

RETN

86

Q9HD89
EEHLDADCCCTAWCV

TTYH3

76

Q9C0H2
QCHAGTGHCWCVDEK

TG

1041

P01266
ESIWACLSCSHVACG

USP44

36

Q9H0E7
TICTCEEGWHCTSEA

CD40

101

P25942
EEGWHCTSEACESCV

CD40

106

P25942
CVCGFDHHCKWLNNC

ZDHHC1

156

Q8WTX9
NCTSGACDVCWHTGP

ADAMTSL3

1591

P82987
QCDLCQDWFHGRCVS

KDM5C

1201

P41229