Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucan 1,4-alpha-glucosidase activity	MGAM MGAM2	6.91e-06	2	53	2	GO:0004339
GeneOntologyMolecularFunction	4-hydroxybutyrate receptor activity	SLC52A1 SLC52A2	6.91e-06	2	53	2	GO:0062124
GeneOntologyMolecularFunction	glucosidase activity	GBA3 MGAM MGAM2	7.85e-06	15	53	3	GO:0015926
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM MGAM2	6.88e-05	5	53	2	GO:0004558
GeneOntologyMolecularFunction	riboflavin transmembrane transporter activity	SLC52A1 SLC52A2	1.03e-04	6	53	2	GO:0032217
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM MGAM2	1.44e-04	7	53	2	GO:0090599
GeneOntologyMolecularFunction	protein serine kinase activity	TRPM6 PIK3CG KSR2 PLK1 PLK3 MAP3K4	3.87e-04	363	53	6	GO:0106310
GeneOntologyMolecularFunction	protein kinase activity	TRPM6 PIK3CG KSR2 ROS1 PLK1 PLK3 MAP3K4	9.92e-04	600	53	7	GO:0004672
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TRPM6 PIK3CG KSR2 PLK1 PLK3 MAP3K4	1.13e-03	446	53	6	GO:0004674
GeneOntologyMolecularFunction	virus receptor activity	SLC52A1 BSG SLC52A2	1.50e-03	85	53	3	GO:0001618
GeneOntologyMolecularFunction	exogenous protein binding	SLC52A1 BSG SLC52A2	1.55e-03	86	53	3	GO:0140272
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TRPM6 PIK3CG KSR2 ROS1 PLK1 PLK3 MAP3K4	2.57e-03	709	53	7	GO:0016773
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	GBA3 MGAM MGAM2	2.59e-03	103	53	3	GO:0004553
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TRPM6 PIK3CG KSR2 PAPOLB ROS1 PLK1 PLK3 MAP3K4	3.12e-03	938	53	8	GO:0016772
GeneOntologyMolecularFunction	kinase activity	TRPM6 PIK3CG KSR2 ROS1 PLK1 PLK3 MAP3K4	3.89e-03	764	53	7	GO:0016301
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	SLC52A1 SLC52A2	4.11e-03	36	53	2	GO:0090482
GeneOntologyBiologicalProcess	flavin-containing compound biosynthetic process	SLC52A1 SLC52A2	6.20e-05	5	52	2	GO:0042727
GeneOntologyBiologicalProcess	riboflavin metabolic process	SLC52A1 SLC52A2	6.20e-05	5	52	2	GO:0006771
GeneOntologyBiologicalProcess	flavin adenine dinucleotide biosynthetic process	SLC52A1 SLC52A2	6.20e-05	5	52	2	GO:0072388
GeneOntologyBiologicalProcess	flavin-containing compound metabolic process	SLC52A1 SLC52A2	9.29e-05	6	52	2	GO:0042726
GeneOntologyBiologicalProcess	flavin adenine dinucleotide metabolic process	SLC52A1 SLC52A2	9.29e-05	6	52	2	GO:0072387
GeneOntologyBiologicalProcess	riboflavin transport	SLC52A1 SLC52A2	9.29e-05	6	52	2	GO:0032218
GeneOntologyCellularComponent	U2-type catalytic step 1 spliceosome	PRPF8 SNRNP200	6.06e-04	14	55	2	GO:0071006
GeneOntologyCellularComponent	catalytic step 1 spliceosome	PRPF8 SNRNP200	6.06e-04	14	55	2	GO:0071012
GeneOntologyCellularComponent	9+2 non-motile cilium	STRC STRCP1	6.06e-04	14	55	2	GO:0097732
GeneOntologyCellularComponent	kinocilium	STRC STRCP1	6.06e-04	14	55	2	GO:0060091
GeneOntologyCellularComponent	stereocilium	LOXHD1 STRC STRCP1	7.99e-04	69	55	3	GO:0032420
Domain	Riboflavin_transptr	SLC52A1 SLC52A2	2.46e-05	3	54	2	IPR009357
Domain	DUF1011	SLC52A1 SLC52A2	2.46e-05	3	54	2	PF06237
Domain	POLO_box_2	PLK1 PLK3	2.46e-05	3	54	2	IPR033695
Domain	-	PLK1 PLK3	4.90e-05	4	54	2	3.30.1120.30
Domain	POLO_box	PLK1 PLK3	4.90e-05	4	54	2	PF00659
Domain	POLO_BOX	PLK1 PLK3	4.90e-05	4	54	2	PS50078
Domain	POLO_box_1	PLK1 PLK3	4.90e-05	4	54	2	IPR033701
Domain	NtCtMGAM_N	MGAM MGAM2	4.90e-05	4	54	2	PF16863
Domain	Gal_mutarotase_N	MGAM MGAM2	4.90e-05	4	54	2	IPR031727
Domain	POLO_box_dom	PLK1 PLK3	8.16e-05	5	54	2	IPR000959
Domain	Exostosin	EXT2 RXYLT1	8.16e-05	5	54	2	IPR004263
Domain	Exostosin	EXT2 RXYLT1	8.16e-05	5	54	2	PF03016
Domain	Glyco_hydro_31_AS	MGAM MGAM2	1.22e-04	6	54	2	IPR030458
Domain	Glyco_hydro_31	MGAM MGAM2	1.71e-04	7	54	2	IPR000322
Domain	Glyco_hydro_31	MGAM MGAM2	1.71e-04	7	54	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM MGAM2	1.71e-04	7	54	2	PS00129
Domain	Trefoil	MGAM MGAM2	2.27e-04	8	54	2	PF00088
Domain	P_TREFOIL_2	MGAM MGAM2	2.92e-04	9	54	2	PS51448
Domain	PD	MGAM MGAM2	2.92e-04	9	54	2	SM00018
Domain	-	MGAM MGAM2	4.44e-04	11	54	2	4.10.110.10
Domain	Glycoside_hydrolase_SF	GBA3 MGAM MGAM2	4.83e-04	53	54	3	IPR017853
Domain	P_trefoil_dom	MGAM MGAM2	5.32e-04	12	54	2	IPR000519
Domain	Kinase-like_dom	TRPM6 PIK3CG KSR2 ROS1 PLK1 PLK3 MAP3K4	9.06e-04	542	54	7	IPR011009
Domain	Gal_mutarotase_SF_dom	MGAM MGAM2	1.09e-03	17	54	2	IPR011013
Domain	fn3	CHL1 IL12RB1 MYOM1 ROS1	1.23e-03	162	54	4	PF00041
Domain	FN3	CHL1 IL12RB1 MYOM1 ROS1	2.00e-03	185	54	4	SM00060
Domain	Ig_I-set	CHL1 MYOM1 BSG NEXN	2.21e-03	190	54	4	IPR013098
Domain	I-set	CHL1 MYOM1 BSG NEXN	2.21e-03	190	54	4	PF07679
Domain	FN3	CHL1 IL12RB1 MYOM1 ROS1	2.61e-03	199	54	4	PS50853
Domain	-	NBEAL1 CALR CLSTN2	2.62e-03	95	54	3	2.60.120.200
Domain	FN3_dom	CHL1 IL12RB1 MYOM1 ROS1	3.11e-03	209	54	4	IPR003961
Domain	-	PIK3CG DYSF SNRNP200	9.00e-03	148	54	3	2.60.40.150
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	2.46e-06	2	55	2	11687802
Pubmed	Riboflavin uptake transporter Slc52a2 (RFVT2) is upregulated in the mouse mammary gland during lactation.	SLC52A1 SLC52A2	2.46e-06	2	55	2	26791833
Pubmed	PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects.	PRPF8 SNRNP200	2.46e-06	2	55	2	38605034
Pubmed	Polo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosis.	PLK1 PLK3	2.46e-06	2	55	2	16478733
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	2.46e-06	2	55	2	34910522
Pubmed	Complete Deletion of Slc52a2 Causes Embryonic Lethality in Mice.	SLC52A1 SLC52A2	2.46e-06	2	55	2	33518683
Pubmed	Identification of receptors for pig endogenous retrovirus.	SLC52A1 SLC52A2	2.46e-06	2	55	2	12740431
Pubmed	MAL protein suppresses the metastasis and invasion of GC cells by interfering with the phosphorylation of STAT3.	MAL STAT3	2.46e-06	2	55	2	35093120
Pubmed	Variability in clinical phenotypes of PRPF8-linked autosomal dominant retinitis pigmentosa correlates with differential PRPF8/SNRNP200 interactions.	PRPF8 SNRNP200	2.46e-06	2	55	2	29087248
Pubmed	Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells.	PLK1 STAT3	2.46e-06	2	55	2	22108192
Pubmed	The inactive C-terminal cassette of the dual-cassette RNA helicase BRR2 both stimulates and inhibits the activity of the N-terminal helicase unit.	PRPF8 SNRNP200	2.46e-06	2	55	2	31914407
Pubmed	Involvement of riboflavin transporter RFVT2/Slc52a2 in hepatic homeostasis of riboflavin in mice.	SLC52A1 SLC52A2	2.46e-06	2	55	2	23911957
Pubmed	Inhibition of RNA helicase Brr2 by the C-terminal tail of the spliceosomal protein Prp8.	PRPF8 SNRNP200	2.46e-06	2	55	2	23704370
Pubmed	The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase.	PLK1 PLK3	2.46e-06	2	55	2	11931760
Pubmed	Madras motor neuron disease (MMND) is distinct from the riboflavin transporter genetic defects that cause Brown-Vialetto-Van Laere syndrome.	SLC52A1 SLC52A2	7.36e-06	3	55	2	24139842
Pubmed	Dual PLK1 and STAT3 inhibition promotes glioblastoma cells apoptosis through MYC.	PLK1 STAT3	7.36e-06	3	55	2	32962858
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	7.36e-06	3	55	2	30801007
Pubmed	CD147/basigin limits lupus nephritis and Th17 cell differentiation in mice by inhibiting the interleukin-6/STAT-3 pathway.	BSG STAT3	7.36e-06	3	55	2	25891969
Pubmed	SLC52A3, A Brown-Vialetto-van Laere syndrome candidate gene is essential for mouse development, but dispensable for motor neuron differentiation.	SLC52A1 SLC52A2	7.36e-06	3	55	2	26976849
Pubmed	Embigin/basigin subgroup of the immunoglobulin superfamily: different modes of expression during mouse embryogenesis and correlated expression with carbohydrate antigenic markers.	BSG FUT4	7.36e-06	3	55	2	9639355
Pubmed	Plk3 phosphorylates topoisomerase IIalpha at Thr(1342), a site that is not recognized by Plk1.	PLK1 PLK3	7.36e-06	3	55	2	18062778
Pubmed	Mutation Analysis of Pre-mRNA Splicing Genes PRPF31, PRPF8, and SNRNP200 in Chinese Families with Autosomal Dominant Retinitis Pigmentosa.	PRPF8 SNRNP200	7.36e-06	3	55	2	30360737
Pubmed	Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells.	IL12RB1 STAT3	7.36e-06	3	55	2	18591412
Pubmed	Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.	IL12RB1 STAT3	7.36e-06	3	55	2	23673666
Pubmed	The Expression of Riboflavin Transporters in Human Colorectal Cancer.	SLC52A1 SLC52A2	7.36e-06	3	55	2	29715086
Pubmed	Riboflavin Transporter Deficiency	SLC52A1 SLC52A2	7.36e-06	3	55	2	26072523
Pubmed	Novel riboflavin transporter family RFVT/SLC52: identification, nomenclature, functional characterization and genetic diseases of RFVT/SLC52.	SLC52A1 SLC52A2	7.36e-06	3	55	2	23506902
Pubmed	Stat3 regulates centrosome clustering in cancer cells via Stathmin/PLK1.	PLK1 STAT3	7.36e-06	3	55	2	28474672
Pubmed	HAb18G/CD147 promotes pSTAT3-mediated pancreatic cancer development via CD44s.	BSG STAT3	7.36e-06	3	55	2	24132924
Pubmed	Identification and comparative functional characterization of a new human riboflavin transporter hRFT3 expressed in the brain.	SLC52A1 SLC52A2	7.36e-06	3	55	2	20463145
Pubmed	Structure of a multipartite protein-protein interaction domain in splicing factor prp8 and its link to retinitis pigmentosa.	PRPF8 SNRNP200	7.36e-06	3	55	2	17317632
Pubmed	A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.	PRPF8 SNRNP200 DYNC1H1	7.40e-06	24	55	3	33705438
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	1.47e-05	4	55	2	18849963
Pubmed	Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex.	PRPF8 SNRNP200	1.47e-05	4	55	2	29361316
Pubmed	Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain.	PLK1 PLK3	1.47e-05	4	55	2	11901158
Pubmed	Calreticulin promotes cell motility and enhances resistance to anoikis through STAT3-CTTN-Akt pathway in esophageal squamous cell carcinoma.	CALR STAT3	1.47e-05	4	55	2	19684620
Pubmed	Identification and assessment of PLK1/2/3/4 in lung adenocarcinoma and lung squamous cell carcinoma: Evidence from methylation profile.	PLK1 PLK3	1.47e-05	4	55	2	34080290
Pubmed	CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells.	BSG STAT3	2.45e-05	5	55	2	25428919
Pubmed	Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.	PLK1 PLK3	2.45e-05	5	55	2	19597481
Pubmed	Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody.	PLK1 PLK3	2.45e-05	5	55	2	12493754
Pubmed	Expression of angiogenic regulators, VEGF and leptin, is regulated by the EGF/PI3K/STAT3 pathway in colorectal cancer cells.	PIK3CG STAT3	2.45e-05	5	55	2	19492417
Pubmed	Wortmannin, a widely used phosphoinositide 3-kinase inhibitor, also potently inhibits mammalian polo-like kinase.	PIK3CG PLK1	2.45e-05	5	55	2	15664519
Pubmed	Mammalian Polo-like kinase 3 (Plk3) is a multifunctional protein involved in stress response pathways.	PLK1 PLK3	2.45e-05	5	55	2	12242661
Pubmed	Phosphorylation of synucleins by members of the Polo-like kinase family.	PLK1 PLK3	2.45e-05	5	55	2	19889641
Pubmed	Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro.	PLK1 PLK3	2.45e-05	5	55	2	10973490
Pubmed	The human U5-220kD protein (hPrp8) forms a stable RNA-free complex with several U5-specific proteins, including an RNA unwindase, a homologue of ribosomal elongation factor EF-2, and a novel WD-40 protein.	PRPF8 SNRNP200	2.45e-05	5	55	2	9774689
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	2.45e-05	5	55	2	24920589
Pubmed	The human homologue of the yeast splicing factor prp6p contains multiple TPR elements and is stably associated with the U5 snRNP via protein-protein interactions.	PRPF8 SNRNP200	3.67e-05	6	55	2	10788320
Pubmed	Tumor suppressor RBM5 directly interacts with the DExD/H-box protein DHX15 and stimulates its helicase activity.	PRPF8 SNRNP200	3.67e-05	6	55	2	22569250
Pubmed	A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.	IL12RB1 STAT3	5.13e-05	7	55	2	12023369
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	PRPF8 PLK1 SNRNP200 DYNC1H1 STAT3	5.35e-05	256	55	5	33397691
Pubmed	Genotoxic stress-induced activation of Plk3 is partly mediated by Chk2.	PLK1 PLK3	6.83e-05	8	55	2	12548019
Pubmed	Death by splicing: tumor suppressor RBM5 freezes splice-site pairing.	PRPF8 SNRNP200	6.83e-05	8	55	2	18951082
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	STRC STRCP1	6.83e-05	8	55	2	21165971
Pubmed	Diverse genome-wide association studies associate the IL12/IL23 pathway with Crohn Disease.	IL12RB1 STAT3	6.83e-05	8	55	2	19249008
Pubmed	The composition and signaling of the IL-35 receptor are unconventional.	IL12RB1 STAT3	8.78e-05	9	55	2	22306691
Pubmed	Genetic modifiers of muscular dystrophy: implications for therapy.	ITGA7 DYSF	8.78e-05	9	55	2	16916601
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	GGCT CALR PRPF8 NEXN SNRNP200 DYNC1H1	1.06e-04	477	55	6	31300519
Pubmed	Structure of a human catalytic step I spliceosome.	PRPF8 SNRNP200	1.10e-04	10	55	2	29301961
Pubmed	A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.	PRPF8 SNRNP200 DYNC1H1	1.26e-04	61	55	3	19875381
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	LOXHD1 BSG PRPF8 DYSF PLK1 MAP3K4	1.32e-04	497	55	6	36774506
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	STRC STRCP1	1.34e-04	11	55	2	31448880
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	STRC STRCP1	1.34e-04	11	55	2	31776257
Pubmed	Genome-wide CRISPR-cas9 knockout screening identifies GRB7 as a driver for MEK inhibitor resistance in KRAS mutant colon cancer.	PLK1 SNRNP200 STAT3	1.39e-04	63	55	3	34718347
Pubmed	The nuclear cap-binding complex interacts with the U4/U6·U5 tri-snRNP and promotes spliceosome assembly in mammalian cells.	PRPF8 SNRNP200	1.60e-04	12	55	2	23793891
Pubmed	USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation.	PLK1 DYNC1H1	1.60e-04	12	55	2	29293652
Pubmed	Colony-stimulating factor-1 requires PI3-kinase-mediated metabolism for proliferation and survival in myeloid cells.	PIK3CG STAT3	1.60e-04	12	55	2	16514418
Pubmed	Phospho-Bcl-x(L)(Ser62) plays a key role at DNA damage-induced G(2) checkpoint.	PLK1 PLK3	1.60e-04	12	55	2	22617334
Pubmed	Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice.	SLC52A1 SLC52A2	1.60e-04	12	55	2	33116204
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	BSG PRPF8 NEXN SNRNP200 DYNC1H1	1.83e-04	333	55	5	32665550
Pubmed	Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes.	PLK1 PLK3	1.89e-04	13	55	2	22854038
Pubmed	The network of protein-protein interactions within the human U4/U6.U5 tri-snRNP.	PRPF8 SNRNP200	1.89e-04	13	55	2	16723661
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	CALR PRPF8 NEXN SNRNP200 DYNC1H1 STAT3	2.03e-04	538	55	6	28524877
Pubmed	Human U4/U6.U5 and U4atac/U6atac.U5 tri-snRNPs exhibit similar protein compositions.	PRPF8 SNRNP200	2.21e-04	14	55	2	11971955
Pubmed	Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.	DTX1 KSR2 GPATCH2 CLSTN2	2.51e-04	193	55	4	22589738
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	MED17 PRPF8 PLK1 SNRNP200 DYNC1H1 STAT3	2.52e-04	560	55	6	35241646
Pubmed	Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.	CALR DYSF	2.54e-04	15	55	2	26403541
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	BSG PRPF8 SNRNP200 DYNC1H1	2.72e-04	197	55	4	31620119
Pubmed	Human immunodeficiency virus type 1 Tat accelerates Kaposi sarcoma-associated herpesvirus Kaposin A-mediated tumorigenesis of transformed fibroblasts in vitro as well as in nude and immunocompetent mice.	PIK3CG STAT3	2.90e-04	16	55	2	20019835
Pubmed	miR-24 controls the regenerative competence of hair follicle progenitors by targeting Plk3.	PLK1 PLK3	2.90e-04	16	55	2	34107258
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CALR PRPF8 NEXN SNRNP200	2.99e-04	202	55	4	24639526
Pubmed	Host cell interactome of HIV-1 Rev includes RNA helicases involved in multiple facets of virus production.	CALR PRPF8 SNRNP200 DYNC1H1	3.22e-04	206	55	4	22174317
Pubmed	Mammalian Otolin: a multimeric glycoprotein specific to the inner ear that interacts with otoconial matrix protein Otoconin-90 and Cerebellin-1.	STRC STRCP1	3.29e-04	17	55	2	20856818
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	TRPM6 GBA3 GGCT BSG CALR PRPF8 SNRNP200 DYNC1H1 MGAM2	3.68e-04	1425	55	9	30948266
Pubmed	BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing.	PRPF8 SNRNP200	4.13e-04	19	55	2	25263594
Pubmed	Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.	BSG NEXN DYNC1H1	4.25e-04	92	55	3	37343697
Pubmed	Large-Scale Functional Assessment of Genes Involved in Rare Diseases with Intellectual Disabilities Unravels Unique Developmental and Behaviour Profiles in Mouse Models.	MED17 DYNC1H1	4.58e-04	20	55	2	36551904
Pubmed	Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.	ITGA7 STAT3	5.56e-04	22	55	2	28334989
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	PIK3CG PLK1 PLK3	5.75e-04	102	55	3	20508983
Pubmed	Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity.	PLK1 DYNC1H1	6.08e-04	23	55	2	36973253
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	PRPF8 SNRNP200 DYNC1H1	6.09e-04	104	55	3	36055981
Pubmed	Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.	FUT4 PLK3	7.79e-04	26	55	2	15890332
Pubmed	Unconventional myosin VI in the heart: Involvement in cardiac dysfunction progressing with age.	CALR DYSF	8.40e-04	27	55	2	37169038
Pubmed	ISG15 Connects Autophagy and IFN-γ-Dependent Control of Toxoplasma gondii Infection in Human Cells.	PRPF8 SNRNP200 DYNC1H1 STAT3	8.64e-04	268	55	4	33024031
Pubmed	Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.	PRPF8 SNRNP200	9.04e-04	28	55	2	19596686
Pubmed	Mediator and cohesin connect gene expression and chromatin architecture.	MED17 STAT3	9.04e-04	28	55	2	20720539
Pubmed	Genetic risk profiling and prediction of disease course in Crohn's disease patients.	CLSTN2 STAT3	9.04e-04	28	55	2	19422935
Pubmed	Mechanism of 5' splice site transfer for human spliceosome activation.	PRPF8 SNRNP200	9.70e-04	29	55	2	30975767
Pubmed	Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemia.	IL12RB1 STAT3	9.70e-04	29	55	2	20716621
Pubmed	Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis.	BSG PLK1	1.04e-03	30	55	2	27179789
Cytoband	15q15.3	STRC STRCP1	4.15e-04	25	55	2	15q15.3
Cytoband	7q34	MGAM FAM131B MGAM2	1.08e-03	167	55	3	7q34
Cytoband	Ensembl 112 genes in cytogenetic band chr7q34	MGAM FAM131B MGAM2	1.45e-03	185	55	3	chr7q34
Cytoband	Ensembl 112 genes in cytogenetic band chr11q21	FUT4 MED17	2.63e-03	63	55	2	chr11q21
GeneFamily	Fibronectin type III domain containing	CHL1 IL12RB1 MYOM1 ROS1	2.79e-04	160	36	4	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	CHL1 MYOM1 BSG NEXN	2.86e-04	161	36	4	593
ToppCell	COVID_vent-Myeloid-Monocytic-Developing_Neutrophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	TRPM6 MGAM LOXHD1 FAR2 FUT4 DYSF	1.49e-07	195	55	6	de23409b1b4146b8ae286850b829ec8dceed0117
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB1 SLC17A9 DTX1 CST7 GRM8	1.56e-06	159	55	5	4750ba9ca06ed97b18df3c74eeb51d3ac8763f63
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 SLC17A9 DTX1 CST7 GRM8	1.66e-06	161	55	5	8e787cc7f5e818cad1a6ed143a5fe310993e030b
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 SLC17A9 DTX1 CST7 GRM8	1.66e-06	161	55	5	ca9233370490e27b9a1892669d6b82db2136180e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CHL1 SLC17A9 PRSS22 GPATCH2 MAP3K4	3.19e-06	184	55	5	01c19a830348ab0b9c02c1546a439de70ee10f97
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHL1 MAL MYOM1 CLSTN2 CDH19	3.19e-06	184	55	5	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic-monocyte-MOP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	GGCT NBEAL1 CALR FUT4 KIF17	4.45e-06	197	55	5	4e68a98bc7e5db7f20e865a0ca21e5a43b3cbb8f
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHL1 LOXHD1 NBEAL1 BSG ITGA7	4.68e-06	199	55	5	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	nucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CHL1 TRPM6 PRSS22 FAM131B	4.79e-05	162	55	4	112fa4de685727f6c8bf6fc4afb82de0524070ad
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL12RB1 SLC17A9 DTX1 CST7	5.39e-05	167	55	4	38b1f052d663fa8f407c54bdd2060216f26feb0e
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAR2 CST7 FUT4 PLK1	5.51e-05	168	55	4	260c768468dff51888f7a68e5424bb174dbaa759
ToppCell	facs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAR2 CST7 FUT4 PLK1	5.51e-05	168	55	4	18d7719a76620d5e5698f9ffd08b4ad4cb7c13f8
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRPM6 LOXHD1 FUT4 PLK1	5.77e-05	170	55	4	cf22a843ae2d9cd6693507fed2b7c6a45abea10e
ToppCell	facs-Heart-RV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 DTX1 CST7 PLK1	5.91e-05	171	55	4	dbffd55db0b3fc6eeb38d05189d84653f0111b31
ToppCell	facs-Heart-RV-24m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 DTX1 CST7 PLK1	5.91e-05	171	55	4	eee1199332c09aaae021134ee7c91661b11df50a
ToppCell	metastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	CHL1 KSR2 CST7 KIF17	6.04e-05	172	55	4	38d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma-6\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	IL12RB1 CST7 SLC52A2 CCNQ	6.18e-05	173	55	4	7714d27e53b02af4e071154cf2ea001fab347235
ToppCell	wk_20-22-Epithelial-PNS\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHL1 MAL CLSTN2 CDH19	6.18e-05	173	55	4	17b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CHL1 MGAM MAL CDH19	6.18e-05	173	55	4	922356a5b4c84607318ac24d7caa2e235b72b066
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 SLC17A9 DTX1 CST7	6.32e-05	174	55	4	986e591d3d46009e53548dfa1f2126cf31063ef4
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL12RB1 SLC17A9 DTX1 CST7	6.32e-05	174	55	4	785be49a2dbbb1dff0fbced1b48b942c2f4a508d
ToppCell	wk_20-22-Epithelial-PNS-Late_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CHL1 MAL CLSTN2 CDH19	6.60e-05	176	55	4	81924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCell	wk_08-11-Epithelial-PNS-Proliferating_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CHL1 MAL CLSTN2 CDH19	7.05e-05	179	55	4	ab23fee9adab1e63d5b5cd9faba6b9a92beef425
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 MAL CCDC87 CDH19	7.21e-05	180	55	4	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 MAL CCDC87 CDH19	7.21e-05	180	55	4	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	droplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 CLSTN2 ITGA7 NEXN	7.21e-05	180	55	4	b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCell	HSPCs-Neutro_prog.\|HSPCs / Lineage and Cell class	MGAM FAR2 CALR CST7	7.21e-05	180	55	4	328192f4678dcdc01c806362b225e770d23498d6
ToppCell	Pericytes-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	FGD1 PAPOLB CLSTN2 ITGA7	7.36e-05	181	55	4	35c470988a93381eefa300831aabb813fa1b90bd
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal\|TCGA-Colorectal / Sample_Type by Project: Shred V9	TRPM6 GBA3 MAL CDH19	7.36e-05	181	55	4	88f6f56f5f58b479d5db91b32c45934c045f88ea
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 MAL CCDC87 CDH19	7.52e-05	182	55	4	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 MAL GPATCH2 FUT4	8.01e-05	185	55	4	554c5d812197fbf66bf279fcc953277e926ade15
ToppCell	18-Distal-Epithelial-Epithelial\|Distal / Age, Tissue, Lineage and Cell class	CHL1 MAL STRC CDH19	8.01e-05	185	55	4	d2a266724f3f70f746a78034f308d98f8b7a66e3
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 MAL FUT4 CDH19	8.18e-05	186	55	4	d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHL1 MAL ITGA7 CDH19	8.35e-05	187	55	4	6f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYOM1 PAPOLB ITGA7 NEXN	8.35e-05	187	55	4	218c9b4f28499389c43005d9626af2ac01066027
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHL1 MAL ITGA7 CDH19	8.35e-05	187	55	4	8e8b147258982b359447add5027318f5b6d51963
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYOM1 PAPOLB ITGA7 NEXN	8.35e-05	187	55	4	c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	MYOM1 ITGA7 DYSF NEXN	8.52e-05	188	55	4	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 PAPOLB ITGA7 NEXN	8.52e-05	188	55	4	61f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCell	droplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 PAPOLB ITGA7 NEXN	8.52e-05	188	55	4	7553ef7de3575af4cf34704b405b551c1af8eb83
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CHL1 MAL ITGA7 CDH19	8.52e-05	188	55	4	502045a39ffb1e92bd9499848368e8fa971edb88
ToppCell	facs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 ITGA7 CDH19 NEXN	8.52e-05	188	55	4	794fc1d9a726945c42f7eac221eed938309b47a9
ToppCell	wk_08-11-Epithelial-PNS-intermediate_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CHL1 MAL CLSTN2 CDH19	8.52e-05	188	55	4	3f3a744b2615bf72f6119f26087099110c0d21fc
ToppCell	droplet-Kidney-nan-3m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 CLSTN2 ITGA7 NEXN	8.70e-05	189	55	4	a959c9d6a0866582688a4204d625c1e5a123e93d
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3CG DYSF PLK1 KIF17	8.70e-05	189	55	4	b5fa3a619e3b554a1a45a551c9b6369075fe5615
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYOM1 ITGA7 CDH19 NEXN	8.88e-05	190	55	4	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	droplet-Kidney-nan-21m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 CLSTN2 ITGA7 NEXN	8.88e-05	190	55	4	e04f47705851563515b6a66a2634cf7a574f7bda
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 CLSTN2 ITGA7 NEXN	8.88e-05	190	55	4	1803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRPM6 MGAM FAR2 FUT4	9.06e-05	191	55	4	6c1283d51a845cff67ed5e500f7e944165297b53
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYOM1 CLSTN2 ITGA7 NEXN	9.43e-05	193	55	4	88916d9a7d831eb52848599917c04238f8f9812b
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYOM1 CLSTN2 ITGA7 NEXN	9.43e-05	193	55	4	800b0f5705fefcd3608e37801afae8a94474723e
ToppCell	10x5'v1-week_12-13-Hematopoietic-HSC/MPP_and_pro-GMP\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SLC17A9 NBEAL1 CALR CST7	9.62e-05	194	55	4	02b7911d07938f04f369a552dedc614930e4396e
ToppCell	15-Airway-Epithelial-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	CHL1 MAL CDH19 FAM131B	9.82e-05	195	55	4	56356a9aeb67b50a74425be2cd9c50d31416c1b3
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil-promyelocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NBEAL1 CALR CST7 FUT4	1.00e-04	196	55	4	8ff0135e108764a3527acc00a994ced342e1cad1
ToppCell	Bronchial-NucSeq-Stromal-Schwann\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 MAL STRC CDH19	1.00e-04	196	55	4	a90c76d9c57a4491b94a321ba541b792ec5d8e83
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MED17 SNRNP200 STAT3 MAP3K4	1.02e-04	197	55	4	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_nonmyelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CHL1 MAL STRC CDH19	1.02e-04	197	55	4	4a7ff67bb0754e034e6f2a1bd34cde86ee3ef899
ToppCell	10x3'2.3-week_14-16-Myeloid_monocytic-monocyte-MOP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NBEAL1 CALR CST7 FUT4	1.02e-04	197	55	4	cbfe62cd4c38ae3c893b869e8af8defb9777df25
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 ITGA7 DYSF NEXN	1.04e-04	198	55	4	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAL BSG CALR KSR2	1.04e-04	198	55	4	0d9d401190792fd61434f1b82548253187d805f0
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 ITGA7 DYSF NEXN	1.04e-04	198	55	4	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	COVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil\|COVID-19_Mild / Disease, condition lineage and cell class	MGAM FAR2 FUT4 DYSF	1.06e-04	199	55	4	e222b90caf45904d8f763574e7b6aac13333df92
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 CST7 FAM131B MGAM2	1.06e-04	199	55	4	5abfbccae147d399e4234f90ae5cd9529abe4dd1
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYOM1 CLSTN2 ITGA7 NEXN	1.08e-04	200	55	4	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	MYOM1 NBEAL1 CDH19 NEXN	1.08e-04	200	55	4	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Mesoderm\|6m / Sample Type, Dataset, Time_group, and Cell type.	MYOM1 CLSTN2 DYSF NEXN	1.08e-04	200	55	4	0f6851baf0cf2a8b0c95a7a585c4407c330c5f6c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal\|6m / Sample Type, Dataset, Time_group, and Cell type.	MYOM1 CLSTN2 GRM8 NEXN	1.08e-04	200	55	4	13ec8afea86e4a10599c924871ba4e325b0a8013
ToppCell	RV-03._Atrial_Cardiomyocyte\|RV / Chamber and Cluster_Paper	MYOM1 NEXN FAM131B	2.97e-04	105	55	3	49e16b11f16e83a7d17d162c14bce991201bcc2a
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Hilar/Perihilar-3\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	CHL1 MGAM ROS1	3.40e-04	110	55	3	0dde36429126d95d4e7efd91243ce6402ab11cdb
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_1\|Striatum / BrainAtlas - Mouse McCarroll V32	IL12RB1 CDH19 PLK3	3.97e-04	116	55	3	c19974992b315fb873664fe3f5077ff8e907e30c
ToppCell	RV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	MYOM1 NEXN FAM131B	4.60e-04	122	55	3	1cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCell	Posterior_cortex-Macroglia-OLIGODENDROCYTE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	IL12RB1 MAL CDH19	4.83e-04	124	55	3	9f169fa17be1842a6bd83778ff30465a740edd5f
ToppCell	LPS_only-Lymphocytic_NKT-T_cells-iNKT-MAIT\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IL12RB1 SLC52A1 CST7	4.83e-04	124	55	3	05e114fcfe84cfc8d92978a4eda6db4d8a616e0e
ToppCell	PND01-03-samps-Lymphocyte-B_cell-B_cell_1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IL12RB1 SLC17A9 DTX1	5.30e-04	128	55	3	5d82247ceda55017628720ed8b6c36ff7cec8437
ToppCell	PND01-03-samps-Lymphocyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IL12RB1 SLC17A9 DTX1	5.30e-04	128	55	3	d3158825a2178244b57ac5ad2676617fd58d8466
ToppCell	PND01-03-samps-Lymphocyte-B_cell\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	IL12RB1 SLC17A9 DTX1	5.30e-04	128	55	3	7661402dd7cd533c1bfe8d9247cecd88c1be9a5e
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL12RB1 MAL CDH19	5.79e-04	132	55	3	dc6edfa821a1cdc645668b0af5ba5ff80dee10bd
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE-O2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL12RB1 MAL CDH19	5.79e-04	132	55	3	60ced08bda5efc95a6f116cd0c6d1a779d99ed38
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocye.Tnr.Ctps_(Ctps)\|Striatum / BrainAtlas - Mouse McCarroll V32	IL12RB1 CDH19 PLK3	6.05e-04	134	55	3	bc550d3b44f1e1e1c18971c110e816bcffd79d14
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr\|Striatum / BrainAtlas - Mouse McCarroll V32	IL12RB1 CDH19 PLK3	6.05e-04	134	55	3	90a34ae53a602a92f6f998e7cf061d8f4f0da527
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Car3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MYOM1 ROS1 ITGA7	6.05e-04	134	55	3	4ef5f395e321cf04e56560be2502a8aa157682f4
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Synpr\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IL12RB1 MAL CDH19	6.45e-04	137	55	3	b03f19b233c1c809f2cd2b4a7642eeaf254a6289
ToppCell	Hippocampus-Macroglia-OLIGODENDROCYTE\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL12RB1 MAL CDH19	6.45e-04	137	55	3	5e97480f014f1d9267e8126f1d0e58acd22f36aa
ToppCell	Lymphoid-T_cells_(Cd8+_T_cell)\|World / shred on cell class and cell subclass (v4)	IL12RB1 DTX1 CST7	6.73e-04	139	55	3	c85f50fb536f4df6fa4dbdebe48e1ecea1df1121
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM KSR2 STRC	7.02e-04	141	55	3	091b5b72811db5fca2314f4a79d467566920e257
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TRPM6 MGAM DYSF	7.16e-04	142	55	3	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TRPM6 MGAM DYSF	7.31e-04	143	55	3	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Gkn1_Pcdh19\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRSS22 DYSF GRM8	7.46e-04	144	55	3	e8caeb6485f4c8f9a3384570dc69024c2bcc9ab0
ToppCell	BLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)\|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	BSG CALR CST7	7.61e-04	145	55	3	6dd81d53d006fcc206a10969374a11c372f92133
ToppCell	E16.5-samps-Mesenchymal-Pericyte\|E16.5-samps / Age Group, Lineage, Cell class and subclass	RTN4IP1 FUT4 ITGA7	8.07e-04	148	55	3	e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCell	E16.5-samps-Mesenchymal-Pericyte-pericyte_A\|E16.5-samps / Age Group, Lineage, Cell class and subclass	RTN4IP1 FUT4 ITGA7	8.07e-04	148	55	3	c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCell	RV-16._Neuronal\|World / Chamber and Cluster_Paper	CHL1 MAL CDH19	8.23e-04	149	55	3	3a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	IL12RB1 PIK3CG CST7	8.39e-04	150	55	3	6d65df8c0937b498585d1e79919ec73daa354e21
ToppCell	facs-GAT-Fat-3m-Lymphocytic-NK_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 IL12RB1 CST7	8.55e-04	151	55	3	3d07b79ecbcfad13116f0f2b039bd181a7ffe853
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-pDC_progenitor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SLC17A9 CALR KIF17	8.55e-04	151	55	3	8ffd71d847fe1aeebe7f43c4b6ca73efb19d6041
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DXO GGCT	8.55e-04	151	55	3	f41c6558a5874b6464c157027fdf202257c60e5b
ToppCell	P15-Epithelial-epithelial_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CHL1 MAL CDH19	8.72e-04	152	55	3	00d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCell	RV-16._Neuronal\|RV / Chamber and Cluster_Paper	CHL1 MAL CDH19	8.89e-04	153	55	3	bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Liver / Manually curated celltypes from each tissue	CCDC87 RTN4IP1 MAP3K4	9.06e-04	154	55	3	c6308074468235c88ef4ea43ab155d9f86cbf261
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT2_Precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TRPM6 MAL ROS1	9.23e-04	155	55	3	9cad73d0b8ead289e1073d1a2e00bbeb1228308c
Drug	HFCO	CALR PLK1 PLK3	1.41e-06	10	53	3	CID000015153
Drug	AC1L1GT5	GBA3 MGAM CALR KIF17 DYNC1H1	2.79e-06	95	53	5	CID000003829
Drug	NSC-210825	MGAM CALR	5.32e-06	2	53	2	CID000427282
Drug	strictosidine	GBA3 MGAM CST7	1.54e-05	21	53	3	CID000161336
Drug	hydroxylamine sulfate	MGAM CALR	1.59e-05	3	53	2	CID000024846
Drug	N-nonyl-deoxygalactonojirimycin	GBA3 MGAM CALR	2.04e-05	23	53	3	CID000501390
Drug	(2S,3R,4S,5S,6R)-2-benzyl-6-(hydroxymethyl)oxane-3,4,5-triol	GBA3 MGAM FUT4	2.04e-05	23	53	3	CID010332525
Drug	Ro 18-5364	MGAM CALR	3.18e-05	4	53	2	CID000127803
Drug	chloro acetate	CALR FUT4	3.18e-05	4	53	2	CID012616564
Drug	AC1L970Z	GBA3 MGAM CALR	4.17e-05	29	53	3	CID000439275
Drug	calystegine B(1	GBA3 MGAM	5.29e-05	5	53	2	CID000164245
Drug	beta-D-glucopyranosyl azide	GBA3 MGAM	5.29e-05	5	53	2	CID000152302
Drug	acetate	GBA3 MGAM MYOM1 GGCT BSG SLC52A2 PLK1 DYNC1H1	6.84e-05	599	53	8	CID000000175
Drug	beidellite	MGAM CLSTN2	7.93e-05	6	53	2	CID006367228
Drug	conduritol aziridine	GBA3 MGAM	7.93e-05	6	53	2	CID000130051
Drug	AC1NSXES	GBA3 MGAM	7.93e-05	6	53	2	CID005318890
Drug	naphthol-AS-BI	CHL1 GBA3 MGAM	8.75e-05	37	53	3	CID000071060
Drug	dexamethasone; Down 200; 1uM; MCF7; HG-U133A	IL12RB1 MAL CLSTN2 DYSF STAT3	9.44e-05	197	53	5	255_DN
Drug	Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A	CHL1 MGAM SLC52A1 PIK3CG GRM8	9.44e-05	197	53	5	3174_UP
Drug	Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A	CHL1 SLC17A9 ITGA7 KIF17 FAM131B	9.44e-05	197	53	5	6759_UP
Drug	Clopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A	NUDT18 CCDC87 FGD1 GRM8 SNRNP200	9.90e-05	199	53	5	3220_UP
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	GBA3 IL12RB1 MGAM MAL CCDC87	1.01e-04	200	53	5	4740_UP
Drug	CP-944629 [668990-94-1]; Down 200; 10uM; MCF7; HT_HG-U133A	CLSTN2 JADE1 RXYLT1 FUT4 PLK3	1.01e-04	200	53	5	7544_DN
Drug	PTAD	GBA3 MGAM	1.11e-04	7	53	2	CID000077913
Drug	ND2001	GBA3 MGAM	1.11e-04	7	53	2	CID000160207
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	3.17e-06	2	53	2	DOID:0110471 (implicated_via_orthology)
Disease	Brown-Vialetto-Van Laere syndrome (implicated_via_orthology)	SLC52A1 SLC52A2	9.49e-06	3	53	2	DOID:0050694 (implicated_via_orthology)
Disease	late-onset Alzheimers disease	SLC52A1 BSG KSR2 CDH19 DYSF	1.78e-04	292	53	5	EFO_1001870
Disease	epilepsy (implicated_via_orthology)	CHL1 ITGA7 GRM8 DYNC1H1	2.13e-04	163	53	4	DOID:1826 (implicated_via_orthology)
Disease	ovary epithelial cancer (is_marker_for)	PLK1 PLK3	2.44e-04	13	53	2	DOID:2152 (is_marker_for)
Disease	visceral adipose tissue measurement, body mass index	KSR2 GPATCH2 CLSTN2	5.21e-04	87	53	3	EFO_0004340, EFO_0004765
Disease	Attention Deficit Disorder	FGD1 GRM8	7.15e-04	22	53	2	C0041671
Disease	Minimal Brain Dysfunction	FGD1 GRM8	7.15e-04	22	53	2	C1321905
Disease	RS-10-hydroxywarfarin measurement	TRPM6 GBA3 PIK3CG	7.38e-04	98	53	3	EFO_0803330
Disease	Attention deficit hyperactivity disorder	FGD1 GRM8	8.52e-04	24	53	2	C1263846
Disease	retinitis pigmentosa (implicated_via_orthology)	PRPF8 SNRNP200	1.08e-03	27	53	2	DOID:10584 (implicated_via_orthology)
Disease	1,5 anhydroglucitol measurement	MGAM MGAM2	1.25e-03	29	53	2	EFO_0008009
Disease	Large cell carcinoma of lung	TRPM6 ROS1	1.52e-03	32	53	2	C0345958

Protein segments in the cluster

Peptide	Gene	Start	Entry
PDFVPGEWDWNTVLE	CCDC87	646	Q9NVE4
EVPAEVEAEKPWWQV	CCNQ	206	Q8N1B3
VDVKPVCKPGWQDWT	CLSTN2	251	Q9H4D0
VPESVTPVEGDWLVW	NBEAL1	901	Q6ZS30
TGEPKPEITWWFEGE	NEXN	606	Q0ZGT2
VFSEWEWPNPVLLKE	PAPOLB	276	Q9NRJ5
SEVWVVPWLQHFEVP	CST7	126	O76096
IVGATWQEPFPGWVD	FAR2	231	Q96K12
EYRVTWKPQGAPVEW	CHL1	746	O00533
WKPQGAPVEWEEETV	CHL1	751	O00533
WGKVWPDLPNVIVDG	MGAM2	1306	Q2M2H8
EPPKVRGENFSWWKV	NUDT18	286	Q6ZVK8
WEKEWAEAPQEAPGA	FUT4	16	P22083
WGKVWPDFPDVVVNG	MGAM	1351	O43451
NDGDIVWGKVWPDFP	MGAM	2241	O43451
VWGKVWPDFPDVVVN	MGAM	2246	O43451
WPDFPDVVVNGSLDW	MGAM	2251	O43451
EWPFKTQPAEAIIWQ	KSR2	871	Q6VAB6
APGWFVDWVEVDAPS	LOXHD1	1046	Q8IVV2
VGVAWVEPHPVYSWK	PRSS22	121	Q9GZN4
IFQSPGDEVWGVVWK	GGCT	71	O75223
DEEGVVKFQPSLWPW	MED17	81	Q9NVC6
KLEWHSPWAVVPVFV	GRM8	576	O00222
GFPPQNVARVVVWEW	DTX1	16	Q86Y01
KWWAQSFLPGVPNVV	DXO	276	O77932
IEWQGWGKTPAVQPQ	FAM131B	86	Q86XD5
PDPSWKNVDWIYVVP	GBA3	336	Q9H227
AVGSPVPEIQWWFEG	BSG	46	P35613
WEPPVIQNPEYKGEW	CALR	261	P27797
VPWPLVQGWVMFVSV	MAL	46	P21145
EFPGGKETWQWINPV	IL12RB1	591	P42701
ISGEWSPWQAKVPQI	DYNC1H1	2541	Q14204
DPMAVVAEGVPWWVI	ITGA7	1071	Q13683
CGITGVVPWWEKEDP	GPATCH2	296	Q9NW75
SPWINDVDVFQWPLG	RXYLT1	231	Q9Y2B1
PWGNVKPVVVLSSYW	DYSF	651	O75923
VKRGWVWNQFFVPEE	CDH19	41	Q9H159
WDEDNGFWKIPHPVI	KIF17	886	Q9P2E2
SWGTWEAQPVKVVPQ	MAP3K4	916	Q9Y6R4
DEVWAAVPPWKQGTL	RTN4IP1	141	Q8WWV3
KGWHKAWFVVPENEP	FGD1	836	P98174
WVELPVVVKELPEGW	SLC52A2	31	Q9HAB3
PDAKGWIFNVVPWLV	SLC17A9	271	Q9BYT1
WRQEWEKGVQVPVSP	JADE1	76	Q6IE81
FGEVPAWPQELLWAV	STRC	856	Q7RTU9
PKPFTEEVLWNVWLE	PIK3CG	401	P48736
EIPWVIEPVYISQWG	PRPF8	131	Q6P2Q9
VCGLFFVPVVEEWVW	TMEM244	76	Q5VVB8
AQPEPLVWVSKWVDY	PLK3	456	Q9H4B4
KIWTVGIPPWGVIEN	TRPM6	201	Q9BX84
WVELPVVVKDLPEGW	SLC52A1	31	Q9NWF4
PPIGTWDQVAEVLSW	STAT3	496	P40763
YEEWNDPPAVKWGSV	EXT2	426	Q93063
QILWNGPPAVDWGVV	ROS1	966	P08922
VIAPLFPQKREEGWW	SNRNP200	2051	O75643
FPQKREEGWWVVIGD	SNRNP200	2056	O75643
RSWGPWKVVAEQPVG	nan	126	Q6ZS52
FGEVPAWPQELLWAV	STRCP1	856	A6NGW2
VAVKEWWPSVACPEF	ZNF785	136	A8K8V0
EDPACIPIFWVSKWV	PLK1	401	P53350
AGWPEPRVTWYKNQV	MYOM1	301	P52179