Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	diacylglycerol cholinephosphotransferase activity	CEPT1 CHPT1	1.20e-04	3	127	2	GO:0004142
GeneOntologyMolecularFunction	JUN kinase activity	MAPK8 MAPK10	1.20e-04	3	127	2	GO:0004705
GeneOntologyMolecularFunction	acid-amino acid ligase activity	TTLL7 TTLL11 TTL	4.05e-04	23	127	3	GO:0016881
GeneOntologyMolecularFunction	hexosyltransferase activity	GALNT1 GALNT3 EXT2 DPY19L4 CERCAM WDFY3 LARGE1	4.08e-04	211	127	7	GO:0016758
GeneOntologyMolecularFunction	UDP-glycosyltransferase activity	GALNT1 GALNT3 EXT2 CERCAM WDFY3 LARGE1	4.43e-04	153	127	6	GO:0008194
GeneOntologyMolecularFunction	protein kinase activity	TRPM6 CDK18 CDK15 PDGFRB TEK YES1 KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	4.51e-04	600	127	12	GO:0004672
GeneOntologyMolecularFunction	protein serine kinase activity	TRPM6 CDK18 CDK15 KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	5.30e-04	363	127	9	GO:0106310
GeneOntologyMolecularFunction	monoatomic ion channel activity	TRPM6 CACNA1B SLC17A3 PKD1L1 TMEM63B BEST3 BSND BEST4 KCNJ15 CNGA2	7.12e-04	459	127	10	GO:0005216
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TRPM6 CDK18 CDK15 PDGFRB TEK YES1 KSR1 CEPT1 CHPT1 CSNK1G1 ERVK-8 MAP3K9 MAP3K11 MAPK8 MAPK10	9.18e-04	938	127	15	GO:0016772
Domain	PH-BEACH_dom	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	2.32e-12	8	126	6	IPR023362
Domain	-	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	2.32e-12	8	126	6	2.30.29.40
Domain	PH_BEACH	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	2.32e-12	8	126	6	PS51783
Domain	BEACH	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	6.91e-12	9	126	6	PS50197
Domain	Beach	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	6.91e-12	9	126	6	PF02138
Domain	-	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	6.91e-12	9	126	6	1.10.1540.10
Domain	Beach	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	6.91e-12	9	126	6	SM01026
Domain	BEACH_dom	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	6.91e-12	9	126	6	IPR000409
Domain	DUF4704	NBEAL1 NBEA NBEAL2 WDFY3 LRBA	1.29e-11	5	126	5	IPR031570
Domain	DUF4704	NBEAL1 NBEA NBEAL2 WDFY3 LRBA	1.29e-11	5	126	5	PF15787
Domain	PH_BEACH	NBEAL1 NBEA NBEAL2 WDFY3 LRBA	7.70e-11	6	126	5	PF14844
Domain	DUF1088	NBEA LRBA	4.52e-05	2	126	2	IPR010508
Domain	DUF1088	NBEA LRBA	4.52e-05	2	126	2	PF06469
Domain	TTL	TTLL7 TTLL11 TTL	8.16e-05	13	126	3	PS51221
Domain	TTL/TTLL_fam	TTLL7 TTLL11 TTL	8.16e-05	13	126	3	IPR004344
Domain	TTL	TTLL7 TTLL11 TTL	8.16e-05	13	126	3	PF03133
Domain	CHOPT	CEPT1 CHPT1	1.35e-04	3	126	2	IPR014472
Domain	Bestrophin	BEST3 BEST4	2.69e-04	4	126	2	PF01062
Domain	Bestrophin/UPF0187	BEST3 BEST4	2.69e-04	4	126	2	IPR021134
Domain	Bestrophin	BEST3 BEST4	2.69e-04	4	126	2	IPR000615
Domain	MLK1/MLK2/MLK4	MAP3K9 MAP3K11	2.69e-04	4	126	2	IPR016231
Domain	MAP3K10	MAP3K9 MAP3K11	2.69e-04	4	126	2	IPR015785
Domain	Kinase-like_dom	TRPM6 CDK18 CDK15 PDGFRB TEK YES1 KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	3.06e-04	542	126	12	IPR011009
Domain	Tyr_kinase_cat_dom	PDGFRB TEK YES1 MAP3K9 MAP3K11	3.23e-04	88	126	5	IPR020635
Domain	TyrKc	PDGFRB TEK YES1 MAP3K9 MAP3K11	3.23e-04	88	126	5	SM00219
Domain	Nucleotide-diphossugar_trans	GALNT1 GALNT3 EXT2 CERCAM LARGE1	3.23e-04	88	126	5	IPR029044
Domain	Ser-Thr/Tyr_kinase_cat_dom	PDGFRB TEK YES1 KSR1 MAP3K9 MAP3K11	3.48e-04	138	126	6	IPR001245
Domain	WD40	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	3.77e-04	259	126	8	PF00400
Domain	-	SEMA4D NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	4.33e-04	333	126	9	2.130.10.10
Domain	CDP-OH_P_transf	CEPT1 CHPT1	4.46e-04	5	126	2	PF01066
Domain	CDP-OH_P_trans	CEPT1 CHPT1	4.46e-04	5	126	2	IPR000462
Domain	MAPK_JNK	MAPK8 MAPK10	4.46e-04	5	126	2	IPR008351
Domain	CDP_ALCOHOL_P_TRANSF	CEPT1 CHPT1	4.46e-04	5	126	2	PS00379
Domain	WD40/YVTN_repeat-like_dom	SEMA4D NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	4.52e-04	335	126	9	IPR015943
Domain	-	NBEAL1 NBEA WDFY3 LRBA USH2A	4.60e-04	95	126	5	2.60.120.200
Domain	WD40	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	4.73e-04	268	126	8	SM00320
Domain	Prot_kinase_dom	CDK18 CDK15 PDGFRB TEK YES1 KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	4.80e-04	489	126	11	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK18 CDK15 PDGFRB TEK YES1 KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	5.14e-04	493	126	11	PS50011
Domain	WD40_repeat	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	5.21e-04	272	126	8	IPR001680
Domain	WD_REPEATS_1	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	6.02e-04	278	126	8	PS00678
Domain	WD_REPEATS_2	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	6.16e-04	279	126	8	PS50082
Domain	WD_REPEATS_REGION	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	6.16e-04	279	126	8	PS50294
Domain	PKD/REJ-like	PKD1L1 KIAA0319	6.65e-04	6	126	2	IPR002859
Domain	REJ	PKD1L1 KIAA0319	6.65e-04	6	126	2	PF02010
Domain	S_TKc	CDK18 CDK15 TEK KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	7.42e-04	359	126	9	SM00220
Domain	-	KLHL9 KLHL13 KLHL26	7.79e-04	27	126	3	2.130.10.80
Domain	WD40_repeat_dom	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	9.24e-04	297	126	8	IPR017986
Domain	PROTEIN_KINASE_ATP	CDK18 CDK15 PDGFRB TEK YES1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	1.11e-03	459	126	10	PS00107
Domain	HATC_C_dom	ZNF862 ZBED6	1.23e-03	8	126	2	IPR008906
Domain	Dimer_Tnp_hAT	ZNF862 ZBED6	1.23e-03	8	126	2	PF05699
Domain	Gal_Oxidase_b-propeller	KLHL9 KLHL13 KLHL26	1.54e-03	34	126	3	IPR015916
Domain	PKD/Chitinase_dom	PKD1L1 KIAA0319	1.58e-03	9	126	2	IPR022409
Domain	PKD	PKD1L1 KIAA0319	1.58e-03	9	126	2	SM00089
Domain	Pkinase_Tyr	PDGFRB TEK YES1 KSR1 MAP3K11	1.82e-03	129	126	5	PF07714
Domain	-	GALNT1 GALNT3 EXT2 LARGE1	2.20e-03	81	126	4	3.90.550.10
Domain	PKD	PKD1L1 KIAA0319	2.39e-03	11	126	2	PS50093
Domain	PKD_dom	PKD1L1 KIAA0319	2.39e-03	11	126	2	IPR000601
Domain	-	PKD1L1 KIAA0319	2.39e-03	11	126	2	2.60.40.670
Domain	MAPK	MAPK8 MAPK10	2.85e-03	12	126	2	PS01351
Domain	MAP_kinase_CS	MAPK8 MAPK10	2.85e-03	12	126	2	IPR003527
Domain	Ser/Thr_kinase_AS	CDK18 CDK15 KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	2.93e-03	357	126	8	IPR008271
Domain	BTB-kelch_protein	KLHL9 KLHL13 KLHL26	3.04e-03	43	126	3	IPR017096
Domain	PROTEIN_KINASE_ST	CDK18 CDK15 KSR1 CSNK1G1 MAP3K9 MAP3K11 MAPK8 MAPK10	3.19e-03	362	126	8	PS00108
Domain	OLF	MYOC ADGRL2	3.35e-03	13	126	2	PF02191
Domain	OLF	MYOC ADGRL2	3.35e-03	13	126	2	PS51132
Domain	Olfac-like_dom	MYOC ADGRL2	3.35e-03	13	126	2	IPR003112
Domain	OLF	MYOC ADGRL2	3.35e-03	13	126	2	SM00284
Domain	ConA-like_dom	NBEAL1 NBEA NBEAL2 WDFY3 LRBA USH2A	3.72e-03	219	126	6	IPR013320
Domain	-	CNBD1 GGCX CNGA2	4.16e-03	48	126	3	2.60.120.10
Domain	Protein_kinase_ATP_BS	CDK18 CDK15 PDGFRB TEK YES1 CSNK1G1 MAP3K9 MAP3K11	4.20e-03	379	126	8	IPR017441
Domain	RmlC-like_jellyroll	CNBD1 GGCX CNGA2	4.93e-03	51	126	3	IPR014710
Domain	Gal_mutarotase_SF_dom	BEST4 GAA	5.75e-03	17	126	2	IPR011013
Pathway	KEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY	MAP3K9 MAP3K11 MAPK8 MAPK10	7.07e-07	12	89	4	M47929
Pathway	KEGG_MEDICUS_REFERENCE_FAS_JNK_SIGNALING_PATHWAY	FASLG MAPK8 MAPK10	8.36e-06	7	89	3	M47711
Pathway	WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING	MAP3K9 MAP3K11 MAPK8 MAPK10	7.49e-05	36	89	4	M39908
Pathway	PID_FOXO_PATHWAY	FASLG CSNK1G1 MAPK8 MAPK10	2.53e-04	49	89	4	M136
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_PTP	PTPN7 MAPK8 MAPK10	2.57e-04	20	89	3	M47928
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_VPR_TAT_TO_TNF_JNK_SIGNALING_PATHWAY	MAPK8 MAPK10	3.89e-04	5	89	2	M47570
Pathway	KEGG_MEDICUS_ENV_FACTOR_PARAQUAT_TO_FAS_JNK_SIGNALING_PATHWAY	MAPK8 MAPK10	3.89e-04	5	89	2	M49021
Pathway	KEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_TNF_JNK_SIGNALING_PATHWAY	MAPK8 MAPK10	3.89e-04	5	89	2	M49005
Pathway	WP_MTHFR_DEFICIENCY	CHPT1 MTHFR DNMT1	4.47e-04	24	89	3	M39755
Pathway	WP_MAPK_SIGNALING_PATHWAY	PDGFRB FASLG PTPN7 MAP3K11 MAPK8 MAPK10	5.20e-04	160	89	6	MM15990
Pathway	REACTOME_STIMULI_SENSING_CHANNELS	TRPM6 SLC17A3 BEST3 BSND BEST4	5.50e-04	106	89	5	M27200
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_TNF_JNK_SIGNALING_PATHWAY	MAPK8 MAPK10	5.82e-04	6	89	2	M47680
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_IRE1A_JNK_SIGNALING_PATHWAY	MAPK8 MAPK10	5.82e-04	6	89	2	M47698
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_DJ1_TO_FAS_JNK_SIGNALING_PATWHAY	MAPK8 MAPK10	5.82e-04	6	89	2	M47712
Pubmed	HBx activates FasL and mediates HepG2 cell apoptosis through MLK3-MKK7-JNKs signal module.	FASLG MAP3K11 MAPK8	1.94e-07	4	128	3	22509080
Pubmed	Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.	MAP3K9 MAP3K11 MAPK8	4.02e-06	9	128	3	14504284
Pubmed	Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development.	MAP3K11 MAPK8 MAPK10	5.73e-06	10	128	3	27504807
Pubmed	Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.	MAP3K11 MAPK8 MAPK10	5.73e-06	10	128	3	10629060
Pubmed	IAP suppression of apoptosis involves distinct mechanisms: the TAK1/JNK1 signaling cascade and caspase inhibition.	NAIP MAPK8 MAPK10	5.73e-06	10	128	3	11865055
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SEMA4D SRD5A3 IL17REL NPEPPS KIAA0232 NAIP TMEM63B PAQR5 TSPAN9 KLHL9 SMG7 SGSM2 TTLL11 LRBA CTNND1 ZNF512 NSMAF KLHL26	9.15e-06	1489	128	18	28611215
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	CDK18 ASB17 CDK15 PDGFRB YES1 KSR1 KLHL13 MAP3K9 KLHL26	1.04e-05	372	128	9	22939624
Pubmed	Response properties of slow PIII in the Large (vls) mutant.	GPR179 LARGE1	1.34e-05	2	128	2	22865473
Pubmed	The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity.	CEPT1 CHPT1	1.34e-05	2	128	2	12221122
Pubmed	Cloning, genomic organization, and characterization of a human cholinephosphotransferase.	CEPT1 CHPT1	1.34e-05	2	128	2	10893425
Pubmed	Neuroprotective Effects of the Absence of JNK1 or JNK3 Isoforms on Kainic Acid-Induced Temporal Lobe Epilepsy-Like Symptoms.	MAPK8 MAPK10	1.34e-05	2	128	2	28664455
Pubmed	c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in mice.	MAPK8 MAPK10	1.34e-05	2	128	2	21824499
Pubmed	Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation.	MAP3K11 MAPK8	1.34e-05	2	128	2	20150185
Pubmed	Dynamic positive feedback phosphorylation of mixed lineage kinase 3 by JNK reversibly regulates its distribution to Triton-soluble domains.	MAP3K11 MAPK8	1.34e-05	2	128	2	16687404
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	MYADM COL7A1 GALNT1 GALNT3 SGSH EXT2 GGCX CHPT1 SC5D GLCE SURF4 DPY19L4 CERCAM TMEM231 DNMT1	3.75e-05	1201	128	15	35696571
Pubmed	Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects.	FASLG MAP3K11 MAPK8	3.82e-05	18	128	3	23982205
Pubmed	JNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy.	MAPK8 MAPK10	4.02e-05	3	128	2	30685843
Pubmed	The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia.	NBEA LRBA	4.02e-05	3	128	2	28814779
Pubmed	Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.	FASLG MAPK10	4.02e-05	3	128	2	11567045
Pubmed	Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization.	PDGFRB TEK	4.02e-05	3	128	2	19801450
Pubmed	JNK1 is required to preserve cardiac function in the early response to pressure overload.	MAPK8 MAPK10	4.02e-05	3	128	2	16579967
Pubmed	Loss of TRB3 alters dynamics of MLK3-JNK signaling and inhibits cytokine-activated pancreatic beta cell death.	MAP3K11 MAPK8	4.02e-05	3	128	2	25204656
Pubmed	Specific pathophysiological functions of JNK isoforms in the brain.	MAPK8 MAPK10	4.02e-05	3	128	2	15673436
Pubmed	Human c-Jun N-terminal kinase expression and activation in the nervous system.	MAPK8 MAPK10	4.02e-05	3	128	2	10101227
Pubmed	Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells.	MAPK8 MAPK10	4.02e-05	3	128	2	23485395
Pubmed	Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model.	MAPK8 MAPK10	4.02e-05	3	128	2	17056565
Pubmed	The Roles of c-Jun N-Terminal Kinase (JNK) in Infectious Diseases.	MAPK8 MAPK10	4.02e-05	3	128	2	34502556
Pubmed	Sequential glycosylations at the multibasic cleavage site of SARS-CoV-2 spike protein regulate viral activity.	GALNT1 GALNT3	4.02e-05	3	128	2	38755139
Pubmed	VEGFR2 signaling drives meningeal vascular regeneration upon head injury.	PDGFRB TEK	4.02e-05	3	128	2	32737287
Pubmed	Hippocampal c-Jun-N-terminal kinases serve as negative regulators of associative learning.	MAPK8 MAPK10	4.02e-05	3	128	2	20926661
Pubmed	Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity.	MAP3K9 MAP3K11	4.02e-05	3	128	2	8195146
Pubmed	PDGF receptor activation induces p120-catenin phosphorylation at serine 879 via a PKCalpha-dependent pathway.	PDGFRB CTNND1	4.02e-05	3	128	2	18950621
Pubmed	JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis.	MAPK8 MAPK10	4.02e-05	3	128	2	19609503
Pubmed	Dual targeting of IGF-1R and PDGFR inhibits proliferation in high-grade gliomas cells and induces radiosensitivity in JNK-1 expressing cells.	PDGFRB MAPK8	4.02e-05	3	128	2	17568996
Pubmed	cDNA cloning and expression of a novel human UDP-N-acetyl-alpha-D-galactosamine. Polypeptide N-acetylgalactosaminyltransferase, GalNAc-t3.	GALNT1 GALNT3	4.02e-05	3	128	2	8663203
Pubmed	Activation of c-Jun N-terminal kinase mediates gp120IIIB- and nucleoside analogue-induced sensory neuron toxicity.	MAPK8 MAPK10	4.02e-05	3	128	2	15246824
Pubmed	Next-generation sequencing to solve complex inherited retinal dystrophy: A case series of multiple genes contributing to disease in extended families.	PRPF8 USH2A	4.02e-05	3	128	2	28761320
Pubmed	A critical role of neural-specific JNK3 for ischemic apoptosis.	MAPK8 MAPK10	4.02e-05	3	128	2	14657393
Pubmed	SAPKgamma/JNK1 and SAPKalpha/JNK2 mRNA transcripts are expressed in early gestation human placenta and mouse eggs, preimplantation embryos, and trophoblast stem cells.	MAPK8 MAPK10	4.02e-05	3	128	2	15474087
Pubmed	Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study.	SLC2A9 SLC17A3	4.02e-05	3	128	2	18834626
Pubmed	c-Jun N-terminal kinases (JNK) antagonize cardiac growth through cross-talk with calcineurin-NFAT signaling.	MAPK8 MAPK10	4.02e-05	3	128	2	14517246
Pubmed	Cross-talk between remodeling and de novo pathways maintains phospholipid balance through ubiquitination.	CEPT1 CHPT1	4.02e-05	3	128	2	20018880
Pubmed	Targeting Cul3-scaffold E3 ligase complex via KLHL substrate adaptors for cancer therapy.	KLHL9 KLHL13	4.02e-05	3	128	2	33872809
Pubmed	Knockout of c-Jun N-terminal kinases 1, 2 or 3 isoforms induces behavioural changes.	MAPK8 MAPK10	4.02e-05	3	128	2	23428746
Pubmed	The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells.	FASLG SPPL2A	4.02e-05	3	128	2	17557115
Pubmed	Gene expression profile in JNK3 null mice: a novel specific activation of the PI3K/AKT pathway.	MAPK8 MAPK10	4.02e-05	3	128	2	21255018
Pubmed	Sex and age interaction with genetic association of atherogenic uric acid concentrations.	SLC2A9 SLC17A3	4.02e-05	3	128	2	20053405
Pubmed	Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases.	PDGFRB YES1	4.02e-05	3	128	2	7685273
Pubmed	Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus.	GALNT1 GALNT3	4.02e-05	3	128	2	9394011
Pubmed	Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.	MAP3K11 MAPK8 MAPK10	7.12e-05	22	128	3	15767678
Pubmed	Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).	MAPK8 MAPK10	8.02e-05	4	128	2	15228592
Pubmed	JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis.	MAPK8 MAPK10	8.02e-05	4	128	2	12818176
Pubmed	JNK1, JNK2, and JNK3 are involved in P-glycoprotein-mediated multidrug resistance of hepatocellular carcinoma cells.	MAPK8 MAPK10	8.02e-05	4	128	2	20525557
Pubmed	JNK1, JNK2 and JNK3 are p53 N-terminal serine 34 kinases.	MAPK8 MAPK10	8.02e-05	4	128	2	9393873
Pubmed	c-Jun N-terminal kinase 3 deficiency protects neurons from axotomy-induced death in vivo through mechanisms independent of c-Jun phosphorylation.	MAPK8 MAPK10	8.02e-05	4	128	2	15528206
Pubmed	Three novel human VMD2-like genes are members of the evolutionary highly conserved RFP-TM family.	BEST3 BEST4	8.02e-05	4	128	2	12032738
Pubmed	Bestrophin expression and function in the human pancreatic duct cell line, CFPAC-1.	BEST3 BEST4	8.02e-05	4	128	2	19237432
Pubmed	A selective small-molecule inhibitor of c-Jun N-terminal kinase 1.	MAPK8 MAPK10	8.02e-05	4	128	2	19527717
Pubmed	Structure-function analysis of the bestrophin family of anion channels.	BEST3 BEST4	8.02e-05	4	128	2	12907679
Pubmed	Genomic organization and chromosomal localization of three members of the UDP-N-acetylgalactosamine: polypeptide N-acetylgalactosaminyltransferase family.	GALNT1 GALNT3	8.02e-05	4	128	2	9592121
Pubmed	Mutations in a novel gene, VMD2, encoding a protein of unknown properties cause juvenile-onset vitelliform macular dystrophy (Best's disease).	BEST3 BEST4	8.02e-05	4	128	2	9700209
Pubmed	c-JUN N-terminal kinase-1 (JNK1) but not JNK2 or JNK3 is involved in UV signal transduction in human epidermis.	MAPK8 MAPK10	8.02e-05	4	128	2	16824735
Pubmed	Neuronal c-Jun is required for successful axonal regeneration, but the effects of phosphorylation of its N-terminus are moderate.	MAPK8 MAPK10	8.02e-05	4	128	2	22372722
Pubmed	Cloning and characterization of a small-size peptide Zfra that regulates the cytotoxic function of tumor necrosis factor by interacting with JNK1.	FASLG MAPK8	8.02e-05	4	128	2	15629131
Pubmed	Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein.	MAPK8 MAPK10	8.02e-05	4	128	2	15693750
Pubmed	A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.	MAPK8 MAPK10	8.02e-05	4	128	2	10471813
Pubmed	MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival.	MAPK8 MAPK10	8.02e-05	4	128	2	17724133
Pubmed	Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression.	TEK MAPK8	8.02e-05	4	128	2	18401423
Pubmed	APP upregulation contributes to retinal ganglion cell degeneration via JNK3.	MAPK8 MAPK10	8.02e-05	4	128	2	29238071
Pubmed	Cortical interneurons require Jnk1 to enter and navigate the developing cerebral cortex.	MAPK8 MAPK10	8.02e-05	4	128	2	24899703
Pubmed	Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.	AWAT2 KSR1 SMG7 ZBED6 GLCE TAF5L CTNND1	1.11e-04	293	128	7	31741433
Pubmed	The cell-layer- and cell-type-specific distribution of GalNAc-transferases in the ocular surface epithelia is altered during keratinization.	GALNT1 GALNT3	1.33e-04	5	128	2	12506059
Pubmed	Connective tissue growth factor induces collagen I expression in human lung fibroblasts through the Rac1/MLK3/JNK/AP-1 pathway.	MAP3K11 MAPK8	1.33e-04	5	128	2	23906792
Pubmed	BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function.	NBEA LRBA	1.33e-04	5	128	2	12160729
Pubmed	Amyloid beta protein precursor is phosphorylated by JNK-1 independent of, yet facilitated by, JNK-interacting protein (JIP)-1.	MAP3K11 MAPK8	1.33e-04	5	128	2	12917434
Pubmed	The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells.	MAPK8 MAPK10	1.33e-04	5	128	2	12714584
Pubmed	Human immunodeficiency virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen-activated protein kinases in human neurons.	MAPK8 MAPK10	1.33e-04	5	128	2	9403476
Pubmed	Association of polymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease.	MTHFR DNMT1	1.33e-04	5	128	2	23039890
Pubmed	Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.	GALNT1 GALNT3	1.33e-04	5	128	2	9295285
Pubmed	The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity.	MAPK8 MAPK10	1.33e-04	5	128	2	16007099
Pubmed	gp160 of HIV or anti-CD4 monoclonal antibody ligation of CD4 induces inhibition of JNK and ERK-2 activities in human peripheral CD4+ T lymphocytes.	MAPK8 MAPK10	1.33e-04	5	128	2	9045910
Pubmed	Defective N-sulfation of heparan sulfate proteoglycans limits PDGF-BB binding and pericyte recruitment in vascular development.	PDGFRB GLCE	1.33e-04	5	128	2	17289920
Pubmed	cDNA cloning and expression of a novel UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.	GALNT1 GALNT3	1.33e-04	5	128	2	9153242
Pubmed	JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease.	MAPK8 MAPK10	1.33e-04	5	128	2	14704277
Pubmed	The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.	MAPK8 MAPK10	1.33e-04	5	128	2	10230788
Pubmed	Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration.	MAPK8 MAPK10	1.33e-04	5	128	2	20534829
Pubmed	JNK regulates the photic response of the mammalian circadian clock.	MAPK8 MAPK10	1.33e-04	5	128	2	22441692
Pubmed	cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein.	MAPK8 MAPK10	1.33e-04	5	128	2	10756100
Pubmed	Deficiency of the autophagy gene ATG16L1 induces insulin resistance through KLHL9/KLHL13/CUL3-mediated IRS1 degradation.	KLHL9 KLHL13	1.33e-04	5	128	2	31515271
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	GALNT1 NPEPPS KIAA0232 PAQR5 KIAA0319 FOCAD CHPT1 GLCE SURF4 DPY19L4 WDFY3 LRBA SLC23A2	1.53e-04	1061	128	13	33845483
Pubmed	The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex.	NPEPPS GLCE MAPK8 MAPK10 DNMT1	2.00e-04	144	128	5	30585266
Pubmed	The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.	MAPK8 MAPK10	2.00e-04	6	128	2	22327296
Pubmed	Sustained activation of p38 mitogen-activated protein kinase and c-Jun N-terminal kinase pathways by hepatitis B virus X protein mediates apoptosis via induction of Fas/FasL and tumor necrosis factor (TNF) receptor 1/TNF-alpha expression.	FASLG MAPK8	2.00e-04	6	128	2	15542843
Pubmed	HMGB1 is phosphorylated by classical protein kinase C and is secreted by a calcium-dependent mechanism.	MAPK8 MAPK10	2.00e-04	6	128	2	19380828
Pubmed	NGF controls APP cleavage by downregulating APP phosphorylation at Thr668: relevance for Alzheimer's disease.	MAPK8 MAPK10	2.00e-04	6	128	2	27076121
Pubmed	Neuroprotection by histone deacetylase-related protein.	MAPK8 MAPK10	2.00e-04	6	128	2	16611996
Pubmed	Two additional protein-tyrosine kinases expressed in human lung: fourth member of the fibroblast growth factor receptor family and an intracellular protein-tyrosine kinase.	PDGFRB YES1	2.00e-04	6	128	2	1720539
Pubmed	JNK signaling is required for proper tangential migration and laminar allocation of cortical interneurons.	MAPK8 MAPK10	2.00e-04	6	128	2	31915148
Pubmed	An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan.	NBEA LRBA	2.00e-04	6	128	2	19482073
Pubmed	Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells.	PDGFRB TEK	2.00e-04	6	128	2	35273307
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 NBEA NBEAL2 WDFY3 LRBA NSMAF	6.97e-13	9	84	6	1230
GeneFamily	WD repeat domain containing	NBEAL1 EML2 NBEA NBEAL2 TAF5L WDFY3 LRBA NSMAF	2.94e-05	262	84	8	362
GeneFamily	Tubulin tyrosine ligase family	TTLL7 TTLL11 TTL	3.39e-05	14	84	3	779
GeneFamily	Bestrophins	BEST3 BEST4	1.27e-04	4	84	2	866
GeneFamily	Kelch like\|BTB domain containing	KLHL9 KLHL13 KLHL26	9.74e-04	42	84	3	617
GeneFamily	Mitogen-activated protein kinases	MAPK8 MAPK10	1.61e-03	13	84	2	651
GeneFamily	Polypeptide N-acetylgalactosaminyltransferases	GALNT1 GALNT3	3.84e-03	20	84	2	433
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	MYADM SRD5A3 STON1 PDGFRB TMEM63B EXT2 TSPAN9 LIPA SPPL2A SC5D SURF4 TAF5L ADGRL2 SLC23A2 GAA LARGE1	2.04e-07	681	127	16	M5314
Coexpression	MILI_PSEUDOPODIA_HAPTOTAXIS_DN	MYADM SRD5A3 STON1 PDGFRB TMEM63B EXT2 TSPAN9 LIPA SPPL2A SC5D SURF4 TAF5L ADGRL2 SLC23A2 GAA LARGE1	3.12e-07	703	127	16	MM1055
Coexpression	GSE20366_TREG_VS_NAIVE_CD4_TCELL_DN	TRPM6 SLC17A3 SGSH HID1 FASLG FOCAD TTL MMP10	5.94e-06	199	127	8	M4348
ToppCell	facs-Trachea-nan-3m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 MYADM PDGFRB NREP GGCX FRMD6 GAA	1.70e-06	199	127	7	67f78c070c56e44fba36542041bf7fa1c291807c
ToppCell	facs-Trachea-nan-3m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 MYADM PDGFRB NREP GGCX FRMD6 GAA	1.70e-06	199	127	7	1ae244b563f85c1ee8d22698f478c842a4d9c7f5
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	COL7A1 NBEA TTLL11 CERCAM ADGRL2 MAPK10	9.44e-06	170	127	6	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 PTCHD4 TTC4 BSND SPPL2A ADGRL2	1.11e-05	175	127	6	787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 PDGFRB LAMP5 NREP FRMD6 CERCAM	1.31e-05	180	127	6	935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell	5'-Airway_Nasal-Mesenchymal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 PDGFRB LAMP5 NREP FRMD6 CERCAM	1.31e-05	180	127	6	3dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 PAQR5 PTCHD4 KLHL13 LRBA ADGRL2	1.39e-05	182	127	6	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 PDGFRB LAMP5 NREP FRMD6 CERCAM	1.43e-05	183	127	6	803376f5260de83c48d4f7301278d078a32b3e6e
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 PDGFRB LAMP5 NREP FRMD6 CERCAM	1.43e-05	183	127	6	6d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCell	5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 PDGFRB LAMP5 NREP FRMD6 CERCAM	1.43e-05	183	127	6	cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-NK_dim-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PDGFRB FASLG YES1 PTPN7 CERCAM UTY	1.62e-05	187	127	6	0bca79cea4886b66350c56c61859bd71e1e7a85c
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	CRISPLD2 PDGFRB LAMP5 FRMD6 CORIN MMP10	1.62e-05	187	127	6	a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DENND2A PAQR5 SPPL2A KLHL13 LRBA	1.72e-05	189	127	6	977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TRPM6 CRISPLD2 PILRA NAIP KCNJ15 WDFY3	1.72e-05	189	127	6	235c24eeab5139f5821fccd5c879d8787682f4ef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DENND2A PAQR5 KLHL13 LRBA ZNF98	1.77e-05	190	127	6	b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DENND2A PAQR5 SPPL2A KLHL13 LRBA	1.77e-05	190	127	6	e252e925600e6457fa6e362a55217f4cffa75cdb
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 TSPAN9 LRBA MAPK8 MAPK10 LARGE1	1.88e-05	192	127	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PILRA TIGD4 DPP8 LIPA CEPT1 GAA	1.99e-05	194	127	6	b829a63b51b92507a53ffd0393bd9458b2b9440f
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL7A1 SLC2A9 FRMD6 KLHL13 MMP10 ADGRL2	2.17e-05	197	127	6	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NBEA FOCAD UBR3 WDFY3 LRBA UTY	2.30e-05	199	127	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	control-HLA-DR-_S100A+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PLA2G7 CRISPLD2 PILRA NAIP LIPA GAA	2.37e-05	200	127	6	107a0665fb20247511a430178effd7630a619488
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-naive_thymus-derived_CD8-positive,_alpha-beta_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NBEAL2 TTLL11 LRBA SLC23A2 UTY	4.43e-05	136	127	5	9d7080f695de4ef183e3dbdc18ba464a3b8e3469
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1B SLC17A3 HEPHL1 MYO15A USH2A	6.01e-05	145	127	5	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	E16.5-samps\|World / Age Group, Lineage, Cell class and subclass	NREP CENPK EEF1G UTY DNMT1	6.84e-05	149	127	5	e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCell	NS-moderate-d_07-13-Myeloid-Mast_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CDK15 PAQR5 NREP TTLL7 HLTF	8.50e-05	156	127	5	17c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TRPM6 COL7A1 IL17REL PTCHD4 KLHL13	8.76e-05	157	127	5	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYADM KIAA0232 MTHFR LRBA CTNND1	1.02e-04	162	127	5	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HID1 FASLG PTPN7 NSMAF KLHL26	1.08e-04	164	127	5	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HID1 FASLG PTPN7 NSMAF KLHL26	1.08e-04	164	127	5	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HID1 FASLG PTPN7 NSMAF KLHL26	1.08e-04	164	127	5	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NBEA ADGB BEST4 TMEM231 MAPK10	1.24e-04	169	127	5	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND2A STON1 PDGFRB GATA5 ELOVL3	1.34e-04	172	127	5	073a503dc922e3e3ac3528e249b0f8b74402110b
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	COL7A1 PILRA TTLL11 CERCAM ADGRL2	1.34e-04	172	127	5	b66dbfff5e4f53ca8ece91ff9c5dc66a71f07c63
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDK18 DENND2A PDGFRB NREP GPR179	1.38e-04	173	127	5	f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CDK18 DENND2A PDGFRB NREP GPR179	1.38e-04	173	127	5	cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	LAMP5 HID1 SPPL2A ZBED6 GLCE	1.42e-04	174	127	5	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D231\|Adult / Lineage, Cell type, age group and donor	TEK TSPAN9 CC2D2B KLHL13 ADGRL2	1.42e-04	174	127	5	2dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell	moderate-Myeloid-Mast_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CDK15 PAQR5 NREP TTLL7 HLTF	1.46e-04	175	127	5	bbd2971bc6d69e507f90a637834d0936c205c590
ToppCell	droplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 SLC2A9 PDGFRB NBEA HID1	1.50e-04	176	127	5	533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SEMA4D PTPN7 SC5D NBEAL2 DNMT1	1.54e-04	177	127	5	f10f77130dbb2c0ad1b436ceb4fb1deac2b0267c
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPEPPS NBEA KSR1 SGSM2 CTNND1	1.62e-04	179	127	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	CACNA1B NBEA TEK TTLL7 IGSF1	1.62e-04	179	127	5	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	PLA2G7 NAIP TEK WDFY3 MMP10	1.66e-04	180	127	5	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 DENND2A COL7A1 PDGFRB TTLL7	1.66e-04	180	127	5	f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCell	COVID-19-kidney-tDL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC2A9 SLC17A3 PAQR5 KLHL13 KCNJ15	1.66e-04	180	127	5	864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCell	droplet-Lung-nan-18m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK18 DENND2A COL7A1 PDGFRB TTLL7	1.66e-04	180	127	5	dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A3 PAQR5 KLHL13 KCNJ15 MAPK10	1.75e-04	182	127	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	Adult-Mesenchymal-pericyte_cell-D122\|Adult / Lineage, Cell type, age group and donor	CRISPLD2 DENND2A COL7A1 PDGFRB ADGRL2	1.79e-04	183	127	5	fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DENND2A COL7A1 PDGFRB NREP TTLL7	1.84e-04	184	127	5	4cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PAQR5 KLHL13 LRBA ZNF98	1.84e-04	184	127	5	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	CRISPLD2 DENND2A PDGFRB NBEAL1 LIPA	1.84e-04	184	127	5	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	droplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DENND2A COL7A1 PDGFRB NREP TTLL7	1.84e-04	184	127	5	39bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CDK18 TMEM63B CHPT1 BEST4 MMP10	1.89e-04	185	127	5	c3d1a312569f3d619f7295812741cbf068ec6c1f
ToppCell	COVID-19-Fibroblasts-Pericytes\|COVID-19 / group, cell type (main and fine annotations)	CRISPLD2 DENND2A PDGFRB ADGRL2 LARGE1	1.89e-04	185	127	5	4905adaeeffd353e089578e5ea614437dbe794e6
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CDK18 DENND2A PDGFRB GPR179 TTLL7	1.89e-04	185	127	5	b1e84228c95be8ccf7c3c1afb66b71ffb93cf61e
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 PAQR5 AWAT2 BSND LRBA	1.93e-04	186	127	5	8eafd4bea692f7ef33de27dd53f9d1fe67deaad8
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STON1 HID1 DPP8 TEK YES1	1.93e-04	186	127	5	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PAQR5 GSAP KLHL13 LRBA ZNF98	1.98e-04	187	127	5	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	Adult-Mesenchymal-pericyte_cell\|Adult / Lineage, Cell type, age group and donor	CRISPLD2 DENND2A COL7A1 PDGFRB ADGRL2	1.98e-04	187	127	5	62759efb660179402fb574ce5701c89a2e17bcfe
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GALNT3 HID1 GSAP KCNJ15 MAP3K9	1.98e-04	187	127	5	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC2A9 SLC17A3 TTLL7 KCNJ15 WDFY3	1.98e-04	187	127	5	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DENND2A PAQR5 KLHL13 ADGRL2	1.98e-04	187	127	5	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC17A3 PAQR5 KLHL13 KCNJ15 MAPK10	1.98e-04	187	127	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 PAQR5 NBEAL2 KLHL13 ADGRL2	1.98e-04	187	127	5	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	facs-SCAT-Fat-3m\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT1 GGCX EEF1G KLHL9 CERCAM	2.03e-04	188	127	5	b8dff61240e5052c2fbf7f28b86fe41822df45b0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DENND2A SPPL2A KLHL13 LRBA	2.08e-04	189	127	5	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DENND2A KLHL13 LRBA ADGRL2	2.08e-04	189	127	5	975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 DENND2A KLHL13 LRBA ADGRL2	2.08e-04	189	127	5	7eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A WDFY3 LRBA MAPK10 UTY	2.08e-04	189	127	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM6 PAQR5 NBEAL2 KLHL13 ADGRL2	2.08e-04	189	127	5	e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 SEMA4D HID1 TEK KLHL13	2.14e-04	190	127	5	6f71a9f74af7cd9a674753cfc9833ebe5bba0fa2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A PAQR5 TSPAN9 KLHL13 LRBA	2.19e-04	191	127	5	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	control-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CDK15 NBEA TTLL7 SGSM2 HLTF	2.19e-04	191	127	5	afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-immature_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	HID1 TEK CTNND1 ADGRL2 LARGE1	2.24e-04	192	127	5	5af3b2b38495e925497c48f605d618bbf970965d
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYOC HID1 TEK MAP3K11 ARHGAP27	2.30e-04	193	127	5	643f992dbce639e7d147924d8b8f455fcebf215a
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRISPLD2 DENND2A PDGFRB FRMD6 KLHL13	2.30e-04	193	127	5	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NBEA KIAA0319 TTLL11 MAP3K9 MAPK10	2.30e-04	193	127	5	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	wk_15-18\|World / Celltypes from embryonic and fetal-stage human lung	CRISPLD2 GALNT1 ZNF862 CHPT1 KCNJ15	2.30e-04	193	127	5	a28ff1e80e3e741739abe869df5fbd41352a1ea0
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYOC GPR179 CHPT1 IGSF1	2.32e-04	105	127	4	c41264e8b7d306d5d3ffa5b29eb36c7131d1cedf
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYOC GPR179 CHPT1 IGSF1	2.32e-04	105	127	4	ed570cfdd452767dfb4dcae72282fe0fb25a4029
ToppCell	Globus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Gfap_(Gfap)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYOC GPR179 CHPT1 IGSF1	2.32e-04	105	127	4	ed3a431195c42c96c7d9c420e4b9fb00f415012d
ToppCell	nucseq-Mesenchymal-Myocytic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CRISPLD2 DENND2A COL7A1 PDGFRB FRMD6	2.35e-04	194	127	5	2d66091097e106c7bee22e5281f50724700bdf8d
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRISPLD2 DENND2A PDGFRB KLHL13 DNMT1	2.41e-04	195	127	5	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-MMP9+_Inflammatory_macrophage\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLA2G7 PILRA NAIP LIPA GAA	2.41e-04	195	127	5	5a7c74f96f213c504abd65e751800da7e03e47d9
ToppCell	Control-Epithelial_alveolar-AT_1-AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CDK18 MYADM GALNT3 BEST4	2.41e-04	106	127	4	d8868c10785e52a1c22c91e1d0e208f2070393bb
ToppCell	PCW_10-12-Endothelial-Endothelial_immature\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYOC HID1 TEK MAP3K11 ARHGAP27	2.47e-04	196	127	5	c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D PAQR5 KCNJ15 LRBA MAPK10	2.47e-04	196	127	5	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	droplet-Heart-nan-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G7 SEMA4D EML2 HID1 TEK	2.47e-04	196	127	5	e386526332138e636aef2542c11316347a45689c
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PDGFRB FASLG YES1 PTPN7 CERCAM	2.47e-04	196	127	5	c25f90c4e5abfe7cfaa85bfe136c438a5179c978
ToppCell	PCW_13-14-Endothelial-Endothelial_immature\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MYOC HID1 TEK MAP3K11 ARHGAP27	2.47e-04	196	127	5	9ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCell	PCW_10-12-Endothelial\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYOC HID1 TEK MAP3K11 ARHGAP27	2.47e-04	196	127	5	2c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PDGFRB FASLG YES1 PTPN7 CERCAM	2.47e-04	196	127	5	d451f279f4086fcf727af712f98923551181c76e
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	TEK YES1 TSPAN9 CTNND1 ADGRL2	2.52e-04	197	127	5	f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYOC HID1 TEK MAP3K11 ARHGAP27	2.52e-04	197	127	5	a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-NK_dim-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PDGFRB YES1 PTPN7 CERCAM UTY	2.52e-04	197	127	5	76304df40f87224f8e415677e3ee8fb183fe0c03
ToppCell	facs-Trachea-3m\|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYADM EXT2 NREP GGCX GAA	2.52e-04	197	127	5	e77016d64b1cac9825fec7cfe5071f1567401187
ToppCell	10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	HID1 TEK YES1 TSPAN9 CTNND1	2.52e-04	197	127	5	4e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell	facs-Trachea-nan-3m\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYADM EXT2 NREP GGCX GAA	2.52e-04	197	127	5	0353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HID1 TEK MAP3K11 CTNND1 ADGRL2	2.52e-04	197	127	5	797ea1c9f75f88b51fdfc17a2b27ed0199ae64c9
ToppCell	PCW_10-12-Endothelial-Endothelial_cycling\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MYOC HID1 TEK MAP3K11 ARHGAP27	2.58e-04	198	127	5	eac26ed95b4a4343a5dfe1fbecef9374e5947884
Disease	abdominal aortic aneurysm (is_implicated_in)	PLA2G7 MTHFR MAPK8	1.59e-05	12	125	3	DOID:7693 (is_implicated_in)
Disease	rectal benign neoplasm (is_implicated_in)	MTHFR MAPK8	5.33e-05	3	125	2	DOID:1984 (is_implicated_in)
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	WDFY3 NSMAF	1.06e-04	4	125	2	DOID:2935 (implicated_via_orthology)
Disease	glycosyltransferase-like protein LARGE1 measurement	CHPT1 LARGE1	1.06e-04	4	125	2	EFO_0802578
Disease	Testicular Diseases	FASLG IGSF1	1.06e-04	4	125	2	C0039584
Disease	Hydrophthalmos	MYOC TEK	1.77e-04	5	125	2	C0020302
Disease	retinal disease (implicated_via_orthology)	CEPT1 CHPT1	2.64e-04	6	125	2	DOID:5679 (implicated_via_orthology)
Disease	autism spectrum disorder (implicated_via_orthology)	PDGFRB NBEA WDFY3 LRBA CTNND1	4.85e-04	152	125	5	DOID:0060041 (implicated_via_orthology)
Disease	diverticular disease	CRISPLD2 STON1 NREP CENPK TSPAN9 CC2D2B	5.22e-04	236	125	6	EFO_0009959
Disease	coronary artery disease	DXO CDK18 STON1 NBEAL1 TEK TSPAN9 GGCX KIAA0319 BSND LIPA MTHFR ZBED6 N4BP2L2 ADGRL2	5.48e-04	1194	125	14	EFO_0001645
Disease	4-androsten-3beta,17beta-diol disulfate 2 measurement	SLC17A3 ZKSCAN5	6.29e-04	9	125	2	EFO_0021114
Disease	hearing impairment	BSND MYO15A USH2A DNMT1	8.15e-04	98	125	4	C1384666
Disease	ovarian carcinoma, COVID-19	SURF4 ARHGAP27	9.55e-04	11	125	2	EFO_0001075, MONDO_0100096
Disease	Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement	FOCAD MAPK10	9.55e-04	11	125	2	EFO_0003959, EFO_0005939, EFO_0009115, HP_0000175
Disease	open-angle glaucoma (is_implicated_in)	MYOC MTHFR	1.14e-03	12	125	2	DOID:1067 (is_implicated_in)
Disease	tetralogy of Fallot (is_implicated_in)	GATA5 MTHFR	1.35e-03	13	125	2	DOID:6419 (is_implicated_in)
Disease	Acute Cerebrovascular Accidents	PLA2G7 PRPF8 MTHFR	1.57e-03	54	125	3	C0751956
Disease	Diabetic Angiopathies	FASLG MTHFR	2.05e-03	16	125	2	C0011875
Disease	atherosclerosis (is_implicated_in)	PLA2G7 MTHFR	2.05e-03	16	125	2	DOID:1936 (is_implicated_in)
Disease	vitamin C measurement	CHPT1 SLC23A2	2.05e-03	16	125	2	EFO_0600003
Disease	Microangiopathy, Diabetic	FASLG MTHFR	2.05e-03	16	125	2	C0025945
Disease	X-21410 measurement	SLC17A3 ZKSCAN5	2.05e-03	16	125	2	EFO_0800813
Disease	Drug-induced agranulocytosis	GSAP ADGRL2	2.05e-03	16	125	2	HP_0012235
Disease	systemic lupus erythematosus	CDK18 STON1 SLC17A3 FASLG KSR1 CEPT1 SMG7 ELOVL3 CERCAM ARHGAP27	2.17e-03	799	125	10	MONDO_0007915
Disease	Cerebrovascular accident	PLA2G7 PRPF8 MTHFR	2.34e-03	62	125	3	C0038454
Disease	chronic myeloid leukemia (is_implicated_in)	FASLG MTHFR	3.55e-03	21	125	2	DOID:8552 (is_implicated_in)
Disease	Infiltrating duct carcinoma of female breast	CDK15 PDGFRB	3.55e-03	21	125	2	C3165106
Disease	gastric ulcer (biomarker_via_orthology)	TEK FASLG	3.55e-03	21	125	2	DOID:10808 (biomarker_via_orthology)
Disease	Liver diseases	CRISPLD2 SC5D MTHFR	3.58e-03	72	125	3	C0023895
Disease	Liver Dysfunction	CRISPLD2 SC5D MTHFR	3.58e-03	72	125	3	C0086565
Disease	myocardial infarction	STON1 NBEAL1 BSND LIPA N4BP2L2 GAA	3.84e-03	350	125	6	EFO_0000612
Disease	cholangiocarcinoma (is_implicated_in)	FASLG MTHFR	3.89e-03	22	125	2	DOID:4947 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
IYWDDSAARPPYTLA	BEST3	336	Q8N1M1
QYWDEDQPQPPYTVA	BEST4	351	Q8NFU0
TFVTYEPYSSWIPQE	NAIP	66	Q13075
AAVANYTNWAYVPFP	ERVK-8	96	Q902F8
QLWYDQDYARFESPP	DNMT1	866	P26358
YTVTYQEQPPNSWFI	ADGB	991	Q8N7X0
TYSNEVVTLWYRPPD	CDK18	296	Q07002
YFMPWTPYRTDTLIE	ADGRL2	171	O95490
WYEEYPTTPSSFVLN	GLCE	496	O94923
PVLLGYTWSNTYVFP	CC2D2B	1026	Q6DHV5
QYKTWTFVVSPPFEY	CACNA1B	1461	Q00975
DLAQYPVFPWILQDY	NBEAL1	2031	Q6ZS30
HYWPTEEETYGPFQI	PTPN7	206	P35236
WRFYYDPPEFQTIII	HPF1	106	Q9NWY4
VLAFAYPYTWDSLPI	PAQR5	186	Q9NXK6
FWPSLPSYLDAAYEV	MMP10	331	P09238
MVYYPELFVWVSQEP	NREP	1	Q16612
PKSYIYRTQEWDEFP	MTHFR	371	P42898
FVVIYDDPVSYPWIS	SLC17A3	171	O00476
TTPYRVEWEADFEPY	LARGE1	646	O95461
LEYWPVYGTNPLEFE	MAGEE2	236	Q8TD90
HWRFYYDPPEFQTII	nan	106	A8MVJ9
DDALQHPYINVWYDP	MAPK10	351	P53779
TVYYHPESQTLSWEP	IL17REL	211	Q6ZVW7
AQYEEFTPPTVYPWD	GPR179	2351	Q6PRD1
YPEESASAFVYPWVP	MYO15A	401	Q9UKN7
PIISNWFDYIPSTRY	ASB17	236	Q8WXJ9
TFDYAYDWVGRPIPT	CSNK1G1	321	Q9HCP0
LWYTEPIAEYFVPLS	KIAA0232	401	Q92628
PELNSYPRFSDWLYT	KSR1	101	Q8IVT5
LQHPYINVWYDPSEA	MAPK8	316	P45983
QQYPWLSIPFSSIYA	OR51V1	31	Q9H2C8
PSYWAPVFGTNIYAD	CRISPLD2	421	Q9H0B8
SRTSYIPEEIYWGFE	KCNJ15	296	Q99712
PTYPYTQETTWRIDT	MYOC	276	Q99972
EYYSPTLDQWTPIAA	KLHL9	516	Q9P2J3
SYNDLNQYPVFPWVI	LRBA	2236	P50851
NQYPVFPWVITNYES	LRBA	2241	P50851
FIVPYDVWASNYVDL	LAMP5	66	Q9UJQ1
YATALVLWPLYQFDE	MYADM	251	Q96S97
PEYDIWTQFVSADYT	NPEPPSL1	391	A6NEC2
HQDAPYAFLPIWYVE	DXO	366	O77932
LAVVYPFDWQYINPV	PLA2G7	16	Q13093
LNWIPSFPTYDYFNQ	PASD1	21	Q8IV76
DWFEYVSSPNYLAEL	SRD5A3	246	Q9H8P0
YYPWELATAPDVRIS	PILRA	56	Q9UKJ1
TYPAYVSPDVAQSWT	GATA5	141	Q9BWX5
FSWYLENIYPDSQIP	GALNT1	411	Q10472
YFEPEAYFPSWVVSK	FRMD6	176	Q96NE9
DSYIWVQFLYPHIES	GSAP	146	A4D1B5
YCPTATEQAPLWAYI	CEPT1	106	Q9Y6K0
YYDFSIWSEPSDPVE	IGSF1	851	Q8N6C5
SCEYYSPILDQWTPI	KLHL13	556	Q9P2N7
YYVPETDQWTSVSPM	KLHL26	531	Q53HC5
PPYVRLWEEAAYDQS	BSND	96	Q8WZ55
NLYLVVFTPYWPVTV	AWAT2	36	Q6E213
YSSEVVTLWYRPPDA	CDK15	256	Q96Q40
VALIYPFAWQHTYIP	DENND2A	786	Q9ULE3
EEYWATSFPIALIYL	ELOVL3	31	Q9HB03
TWYLNNIYPEVYVPD	GALNT3	486	Q14435
PKLEPFYVERYSWSQ	DPP8	46	Q6V1X1
YVKISDSFWPPYVEL	CENPK	231	Q9BS16
YAPDPQNIYWEHLSI	TMEM63B	411	Q5T3F8
EYSIPLRENWALPYF	DPY19L4	211	Q7Z388
PEQWLEPDTYCYITG	CORIN	916	Q9Y5Q5
YFPLGTWYDLQTVPV	GAA	766	P10253
NYTYVWPVREEYAPT	HEPHL1	161	Q6MZM0
SQYPVFPWIIHDYSS	NSMAF	331	Q92636
PTPYIKAFYNESWER	SLC2A9	81	Q9NRM0
SEYSVEEYQDPEAPW	COL7A1	2856	Q02388
LWYSEYRFPEELTQT	EEF1G	321	P26641
FVTNSGDYEILYWDP	EML2	521	O95834
PPFWEQRNDLYYNTI	HLTF	261	Q14527
PNYTWPFDDIIVFAY	CERCAM	236	Q5T4B2
PWDQEYFDVEPSFTV	PEX1	316	O43933
YFWDESIVQIYIPAA	PKD1L1	1636	Q8TDX9
PEYDIWTQFVSADYT	NPEPPS	391	P55786
GEEVPSDQYYWAPLA	CTNND1	326	O60716
YANPVWTALFDYEPS	MAP3K11	41	Q16584
DAPLPYWTAVFEYEA	MAP3K9	51	P80192
TVGESYQYPPVNWAA	FOCAD	1396	Q5VW36
YVDPMQLPYDSTWEL	PDGFRB	581	P09619
PVWDLDISPYSLYFA	TAF5L	386	O75529
ELLPFTEYEYQVWAV	USH2A	4701	O75445
WPNLEDLYEANVPVY	UTY	1141	O14607
PVDYFWYRETLNIST	SLC6A19	171	Q695T7
QELTYSIWDPGYEEF	SLC6A19	556	Q695T7
VYWLPVYTPEYTEEM	TRMT11	371	Q7Z4G4
YPVFPWVLQDYVSPT	NBEAL2	2096	Q6ZNJ1
YNDLNQYPVFPWVLT	NBEA	2311	Q8NFP9
QYPVFPWVLTNYESE	NBEA	2316	Q8NFP9
YLRNVDPPVWYDTDV	HID1	766	Q8IV36
SPVIGFYVYEPLEYW	PTCHD4	516	Q6ZW05
PSEVKVPEFYWDSSY	SMG7	861	Q92540
KPYFYNPEDSSVRWE	ARHGAP27	426	Q6ZUM4
SVYWDYALVVPFSQV	SGSM2	311	O43147
FWQPYIQTLPSEYDT	SETD3	171	Q86TU7
NVYFNAFWTIPVYKP	SURF4	216	O15260
YAIPWLNEPSFVFAD	SEMA4D	201	Q92854
TILDWFSIPYPSYAI	SGSH	321	P51688
PYYEEWPTLSIYELI	CNBD1	321	Q8NA66
LISYCPTATEEAPYW	CHPT1	81	Q8WUD6
PTATEEAPYWTYLLC	CHPT1	86	Q8WUD6
TWVYPNITDPEYGYL	CNGA2	306	Q16280
PNLYRYIQPWESEFI	PRPF8	1366	Q6P2Q9
NLFPEEYNFYPRSWI	TTLL11	296	Q8NHH1
EYNFYPRSWILPDEF	TTLL11	301	Q8NHH1
PKYNVTEPQIYFDIW	GGCX	456	P38435
YPVFPWILADYDSEE	WDFY3	2726	Q8IZQ1
PWTRKVYEFYSAPIV	TRPM6	826	Q9BX84
QEIPSDWYPFATVQF	STON1	661	Q9Y6Q2
DWYPFATVQFSVPDT	STON1	666	Q9Y6Q2
YTIEDVPPWYLCIFL	SLC23A2	91	Q9UGH3
YSPSWPNFDYTMVVI	SPPL2A	161	Q8TCT8
YAAISYEEWNDPPAV	EXT2	421	Q93063
VDPSTVWYQNVLPYY	TIGD4	156	Q8IY51
GIQFAPYTWSYPEID	TBCC	286	Q15814
LTWQPIFPSSEDDFY	TEK	561	Q02763
NYPYPQIYWVDSSAS	FASLG	6	P48023
TEYDPQPAIQHWYLT	ZNF862	1076	O60290
VNYDYSTLVLSWDPE	ZBED6	951	P86452
YPVEVISYQPGFWEM	TMEM231	251	Q9H6L2
SYYPPWLDDIEILIQ	UBR3	1106	Q6ZT12
TEPPVVYSYFAQDLW	ZNF98	81	A6NK75
YVYPATWPEDDIFRQ	SC5D	16	O75845
CTWFPESYVIYPTNL	TTL	91	Q8NG68
WPVLFLYPEYAQSDF	TTC4	276	O95801
EPPVYAAGSLEEQWY	ZNF512	146	Q96ME7
WSELYPEFFAPLTQN	METTL1	46	Q9UBP6
TDYTDWYPVLGENTV	TSPAN9	151	O75954
TFVPRTWIFPAEYTQ	TTLL7	126	Q6ZT98
TWMQEYNPPTFETFY	ZKSCAN5	36	Q9Y2L8
YVAPADSIQAEEWYF	YES1	146	P07947
APPVETTYNYEWNLI	KIAA0319	361	Q5VV43
ISYWGFPSEEYLVET	LIPA	41	P38571
FTSFRPEWQSVYPFI	N4BP2L2	261	Q92802