Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxalate transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

4.26e-0910444GO:0019531
GeneOntologyMolecularFunctionchloride:bicarbonate antiporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

1.44e-0813444GO:0140900
GeneOntologyMolecularFunctionbicarbonate:monoatomic anion antiporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

1.44e-0813444GO:0140829
GeneOntologyMolecularFunctiontransmembrane transporter activity

OTOP2 CACNA1E PKD2L1 SLC26A3 ABCA3 OTOP3 SLC7A13 SLC26A7 PKDREJ NDUFC2 SLC38A6 SLC26A6 SLC26A4 ANO8 SCN8A

1.55e-0811804415GO:0022857
GeneOntologyMolecularFunctionsulfate transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

3.66e-0816444GO:0015116
GeneOntologyMolecularFunctiontransporter activity

OTOP2 CACNA1E PKD2L1 SLC26A3 ABCA3 OTOP3 SLC7A13 SLC26A7 PKDREJ NDUFC2 SLC38A6 SLC26A6 SLC26A4 ANO8 SCN8A

5.04e-0812894415GO:0005215
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

OTOP2 CACNA1E PKD2L1 SLC26A3 OTOP3 SLC26A7 PKDREJ NDUFC2 SLC26A6 SLC26A4 ANO8 SCN8A

5.66e-087584412GO:0015318
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

OTOP2 CACNA1E PKD2L1 SLC26A3 OTOP3 SLC26A7 PKDREJ NDUFC2 SLC26A6 SLC26A4 ANO8 SCN8A

9.26e-087934412GO:0015075
GeneOntologyMolecularFunctionmonoatomic ion channel activity

OTOP2 CACNA1E PKD2L1 OTOP3 SLC26A7 PKDREJ SLC26A6 ANO8 SCN8A

5.75e-07459449GO:0005216
GeneOntologyMolecularFunctiondicarboxylic acid transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

6.18e-0731444GO:0005310
GeneOntologyMolecularFunctionbicarbonate transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

7.05e-0732444GO:0015106
GeneOntologyMolecularFunctionsolute:inorganic anion antiporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

7.05e-0732444GO:0005452
GeneOntologyMolecularFunctionsecondary active sulfate transmembrane transporter activity

SLC26A3 SLC26A6 SLC26A4

1.63e-0611443GO:0008271
GeneOntologyMolecularFunctionchannel activity

OTOP2 CACNA1E PKD2L1 OTOP3 SLC26A7 PKDREJ SLC26A6 ANO8 SCN8A

1.75e-06525449GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

OTOP2 CACNA1E PKD2L1 OTOP3 SLC26A7 PKDREJ SLC26A6 ANO8 SCN8A

1.78e-06526449GO:0022803
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

FADS2 FADS3 FADS2B

2.81e-0613443GO:0016717
GeneOntologyMolecularFunctiondolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity

ALG10B ALG10

4.75e-062442GO:0106073
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A3 SLC7A13 SLC26A7 SLC38A6 SLC26A6 SLC26A4

5.87e-06207446GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A3 SLC7A13 SLC26A7 SLC38A6 SLC26A6 SLC26A4

6.03e-06208446GO:0005342
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

7.92e-06125445GO:0015108
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4

9.76e-0661444GO:1901682
GeneOntologyMolecularFunctionantiporter activity

SLC26A3 SLC7A13 SLC26A7 SLC26A6 SLC26A4

1.28e-05138445GO:0015297
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

1.98e-05151445GO:0008509
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

3.60e-05171445GO:0015103
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC26A3 SLC7A13 SLC26A7 SLC38A6 SLC26A6 SLC26A4

4.19e-05293446GO:0008514
GeneOntologyMolecularFunctionglycolipid mannosyltransferase activity

PIGV PIGM

4.73e-055442GO:0004376
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC26A3 ABCA3 SLC7A13 SLC26A7 NDUFC2 SLC26A6 SLC26A4

7.57e-05477447GO:0022804
GeneOntologyMolecularFunctionmonoatomic cation channel activity

OTOP2 CACNA1E PKD2L1 OTOP3 PKDREJ SCN8A

1.00e-04343446GO:0005261
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

OTOP2 CACNA1E PKD2L1 OTOP3 PKDREJ NDUFC2 SCN8A

4.06e-04627447GO:0022890
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC26A3 SLC7A13 SLC26A7 SLC26A6 SLC26A4

4.68e-04296445GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC26A3 SLC26A7 NDUFC2 SLC26A6 SLC26A4

5.05e-04301445GO:0022853
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

OTOP2 CACNA1E PKD2L1 OTOP3 PKDREJ NDUFC2 SCN8A

5.72e-04664447GO:0008324
GeneOntologyMolecularFunctionchloride channel activity

SLC26A7 SLC26A6 ANO8

8.99e-0486443GO:0005254
GeneOntologyMolecularFunctionglucosyltransferase activity

ALG10B ALG10

1.07e-0322442GO:0046527
GeneOntologyMolecularFunctionhexosyltransferase activity

PIGV ALG10B ALG10 PIGM

1.18e-03211444GO:0016758
GeneOntologyMolecularFunctionmonoatomic anion channel activity

SLC26A7 SLC26A6 ANO8

1.51e-03103443GO:0005253
GeneOntologyMolecularFunctionproton channel activity

OTOP2 OTOP3

1.61e-0327442GO:0015252
GeneOntologyMolecularFunctionmannosyltransferase activity

PIGV PIGM

1.73e-0328442GO:0000030
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1E PKD2L1 PKDREJ

2.88e-03129443GO:0005262
GeneOntologyMolecularFunctionglycosyltransferase activity

PIGV ALG10B ALG10 PIGM

3.66e-03288444GO:0016757
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1E PKD2L1 PKDREJ

4.47e-03151443GO:0015085
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA3 ANO8

5.65e-0351442GO:0140303
GeneOntologyMolecularFunctionsodium channel activity

PKD2L1 SCN8A

5.87e-0352442GO:0005272
GeneOntologyMolecularFunctionproton transmembrane transporter activity

OTOP2 OTOP3 NDUFC2

8.19e-03188443GO:0015078
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

FADS2 FADS3 FADS2B

8.93e-03194443GO:0016705
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC7A13 SLC38A6

1.07e-0271442GO:0015179
GeneOntologyMolecularFunctionphospholipid transporter activity

ABCA3 ANO8

1.16e-0274442GO:0005548
GeneOntologyBiologicalProcessoxalate transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4

9.66e-0912454GO:0019532
GeneOntologyBiologicalProcesssulfate transmembrane transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4

3.53e-0816454GO:1902358
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

OTOP2 CACNA1E PKD2L1 SLC26A3 OTOP3 SLC26A7 PKDREJ SLC26A6 SLC26A4 ALG10B ANO8 ALG10 SCN8A

1.58e-0710174513GO:0098660
GeneOntologyBiologicalProcessdicarboxylic acid transport

SLC26A3 SLC7A13 SLC26A7 SLC38A6 SLC26A6 SLC26A4

2.31e-07120456GO:0006835
GeneOntologyBiologicalProcesssulfur compound transport

SLC26A3 SLC7A13 SLC26A7 SLC26A6 SLC26A4

2.95e-0765455GO:0072348
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

OTOP2 CACNA1E PKD2L1 SLC26A3 OTOP3 SLC26A7 PKDREJ SLC26A6 SLC26A4 ALG10B ANO8 ALG10 SCN8A

4.54e-0711154513GO:0034220
GeneOntologyBiologicalProcessbicarbonate transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4

1.38e-0638454GO:0015701
GeneOntologyBiologicalProcesschloride transmembrane transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

4.43e-06112455GO:1902476
GeneOntologyBiologicalProcessmonoatomic ion transport

OTOP2 CACNA1E PKD2L1 SLC26A3 OTOP3 SLC26A7 PKDREJ SLC26A6 SLC26A4 ALG10B ANO8 ALG10 SCN8A

4.70e-0613744513GO:0006811
GeneOntologyBiologicalProcesschloride transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

8.52e-06128455GO:0006821
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

1.06e-05134455GO:0098661
GeneOntologyBiologicalProcessorganic anion transport

ACSL3 SLC26A3 SLC7A13 G6PC3 SLC26A7 SLC38A6 SLC26A6 SLC26A4

1.37e-05515458GO:0015711
GeneOntologyBiologicalProcessmonoatomic anion transmembrane transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

2.02e-05153455GO:0098656
GeneOntologyBiologicalProcesscarboxylic acid transport

ACSL3 SLC26A3 SLC7A13 SLC26A7 SLC38A6 SLC26A6 SLC26A4

2.76e-05410457GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

ACSL3 SLC26A3 SLC7A13 SLC26A7 SLC38A6 SLC26A6 SLC26A4

2.84e-05412457GO:0015849
GeneOntologyBiologicalProcessinorganic anion transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

4.41e-05180455GO:0015698
GeneOntologyBiologicalProcessmonoatomic anion transport

SLC26A3 SLC26A7 SLC26A6 SLC26A4 ANO8

4.77e-05183455GO:0006820
GeneOntologyBiologicalProcesslipid biosynthetic process

CERS2 ACSL3 FADS2 ABCA3 FADS3 PIGV FADS2B LPCAT3 PIGM

5.43e-05813459GO:0008610
GeneOntologyBiologicalProcessglycerophospholipid metabolic process

ACSL3 ABCA3 PIGV ABHD16A LPCAT3 PIGM

6.51e-05320456GO:0006650
GeneOntologyBiologicalProcessintracellular pH elevation

SLC26A3 SLC26A6

1.29e-048452GO:0051454
GeneOntologyBiologicalProcessorganophosphate metabolic process

NT5C2 ACSL3 NDUFC2-KCTD14 ABCA3 G6PC3 PIGV NDUFC2 ABHD16A LPCAT3 PIGM

1.40e-0411424510GO:0019637
GeneOntologyBiologicalProcessregulation of phosphatidylcholine metabolic process

ACSL3 ABCA3

2.07e-0410452GO:0150172
GeneOntologyBiologicalProcessunsaturated fatty acid biosynthetic process

FADS2 FADS3 FADS2B

2.48e-0456453GO:0006636
GeneOntologyBiologicalProcessphospholipid metabolic process

ACSL3 ABCA3 PIGV ABHD16A LPCAT3 PIGM

2.51e-04410456GO:0006644
GeneOntologyBiologicalProcessregulation of Golgi to plasma membrane protein transport

PKDCC ACSL3

2.53e-0411452GO:0042996
GeneOntologyBiologicalProcessiodide transport

SLC26A7 SLC26A4

2.53e-0411452GO:0015705
GeneOntologyBiologicalProcessglycerolipid metabolic process

ACSL3 ABCA3 PIGV ABHD16A LPCAT3 PIGM

3.20e-04429456GO:0046486
GeneOntologyBiologicalProcessvery-low-density lipoprotein particle assembly

ACSL3 LPCAT3

4.17e-0414452GO:0034379
GeneOntologyBiologicalProcesspositive regulation of mitochondrial membrane potential

NDUFC2-KCTD14 NDUFC2

5.48e-0416452GO:0010918
GeneOntologyBiologicalProcessphosphatidylcholine metabolic process

ACSL3 ABCA3 LPCAT3

6.58e-0478453GO:0046470
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

OTOP2 CACNA1E PKD2L1 OTOP3 PKDREJ ALG10B ALG10 SCN8A

7.65e-04922458GO:0098662
GeneOntologyBiologicalProcesspositive regulation of ATP biosynthetic process

NDUFC2-KCTD14 NDUFC2

7.77e-0419452GO:2001171
GeneOntologyBiologicalProcessfatty acid biosynthetic process

ACSL3 FADS2 FADS3 FADS2B

7.89e-04191454GO:0006633
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

OTOP2 CACNA1E PKD2L1 OTOP3 PKDREJ ALG10B ALG10 SCN8A

8.79e-04942458GO:0098655
GeneOntologyBiologicalProcesssensory perception of sound

SLC26A4 ALG10B ALG10 SCN8A

9.02e-04198454GO:0007605
GeneOntologyBiologicalProcesscarbohydrate derivative biosynthetic process

ACSL3 NDUFC2-KCTD14 PIGV NDUFC2 ALG10B ALG10 PIGM

9.96e-04736457GO:1901137
GeneOntologyBiologicalProcessdolichol-linked oligosaccharide biosynthetic process

ALG10B ALG10

1.05e-0322452GO:0006488
GeneOntologyBiologicalProcesscarbohydrate derivative metabolic process

NT5C2 ACSL3 NDUFC2-KCTD14 G6PC3 PIGV NDUFC2 ALG10B ALG10 PIGM

1.14e-031226459GO:1901135
GeneOntologyBiologicalProcessdolichol metabolic process

ALG10B ALG10

1.25e-0324452GO:0019348
GeneOntologyBiologicalProcessglycerophospholipid biosynthetic process

ACSL3 PIGV LPCAT3 PIGM

1.27e-03217454GO:0046474
GeneOntologyBiologicalProcesspositive regulation of purine nucleotide biosynthetic process

NDUFC2-KCTD14 NDUFC2

1.35e-0325452GO:1900373
GeneOntologyBiologicalProcesspositive regulation of membrane potential

NDUFC2-KCTD14 NDUFC2

1.35e-0325452GO:0045838
GeneOntologyBiologicalProcessphosphatidylserine metabolic process

ABHD16A LPCAT3

1.35e-0325452GO:0006658
GeneOntologyBiologicalProcesspositive regulation of nucleotide biosynthetic process

NDUFC2-KCTD14 NDUFC2

1.35e-0325452GO:0030810
GeneOntologyBiologicalProcesspositive regulation of lipid transport

C1QTNF1 ABCA3 LPCAT3

1.43e-03102453GO:0032370
GeneOntologyBiologicalProcessregulation of ATP biosynthetic process

NDUFC2-KCTD14 NDUFC2

1.46e-0326452GO:2001169
GeneOntologyBiologicalProcessmembrane lipid metabolic process

CERS2 FADS3 PIGV PIGM

1.54e-03229454GO:0006643
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

SLC26A4 ALG10B ALG10 SCN8A

1.78e-03238454GO:0050954
GeneOntologyBiologicalProcessnegative regulation of reactive oxygen species biosynthetic process

NDUFC2-KCTD14 NDUFC2

1.82e-0329452GO:1903427
GeneOntologyBiologicalProcesspolyprenol metabolic process

ALG10B ALG10

1.82e-0329452GO:0016093
GeneOntologyBiologicalProcessplasma lipoprotein particle assembly

ACSL3 LPCAT3

1.82e-0329452GO:0034377
GeneOntologyBiologicalProcessphosphatidylcholine biosynthetic process

ACSL3 LPCAT3

1.95e-0330452GO:0006656
GeneOntologyBiologicalProcessregulation of pH

SLC26A3 SLC26A6 SLC26A4

2.28e-03120453GO:0006885
GeneOntologyBiologicalProcessGPI anchor biosynthetic process

PIGV PIGM

2.35e-0333452GO:0006506
GeneOntologyBiologicalProcessprotein-lipid complex assembly

ACSL3 LPCAT3

2.35e-0333452GO:0065005
GeneOntologyBiologicalProcessmonocarboxylic acid biosynthetic process

ACSL3 FADS2 FADS3 FADS2B

2.45e-03260454GO:0072330
GeneOntologyBiologicalProcessorganophosphate biosynthetic process

ACSL3 NDUFC2-KCTD14 PIGV NDUFC2 LPCAT3 PIGM

2.62e-03644456GO:0090407
GeneOntologyBiologicalProcessdigestive system process

SLC26A7 SLC26A6 LPCAT3

2.62e-03126453GO:0022600
GeneOntologyBiologicalProcessGPI anchor metabolic process

PIGV PIGM

2.65e-0335452GO:0006505
GeneOntologyBiologicalProcessL-glutamate transmembrane transport

SLC7A13 SLC38A6

2.65e-0335452GO:0015813
GeneOntologyBiologicalProcessphospholipid biosynthetic process

ACSL3 PIGV LPCAT3 PIGM

2.73e-03268454GO:0008654
GeneOntologyBiologicalProcessglycerolipid biosynthetic process

ACSL3 PIGV LPCAT3 PIGM

2.73e-03268454GO:0045017
GeneOntologyBiologicalProcessunsaturated fatty acid metabolic process

FADS2 FADS3 FADS2B

2.74e-03128453GO:0033559
GeneOntologyBiologicalProcesspositive regulation of lipid localization

C1QTNF1 ABCA3 LPCAT3

2.80e-03129453GO:1905954
GeneOntologyCellularComponentendoplasmic reticulum membrane

CERS2 ACSL3 FADS2 FADS3 SPAST G6PC3 PIGV FADS2B LPCAT3 ALG10B ALG10 PIGM

1.62e-0512934612GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

CERS2 ACSL3 FADS2 FADS3 SPAST G6PC3 PIGV FADS2B LPCAT3 ALG10B ALG10 PIGM

1.70e-0512994612GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

CERS2 ACSL3 FADS2 FADS3 SPAST G6PC3 PIGV FADS2B LPCAT3 ALG10B ALG10 PIGM

2.10e-0513274612GO:0042175
GeneOntologyCellularComponentmannosyltransferase complex

PIGV PIGM

4.72e-055462GO:0031501
GeneOntologyCellularComponentapical plasma membrane

SLC26A3 SLC7A13 SLC26A7 F2RL2 SLC26A6 SLC26A4

6.59e-04487466GO:0016324
GeneOntologyCellularComponentbrush border membrane

SLC26A3 SLC26A6 SLC26A4

8.10e-0483463GO:0031526
GeneOntologyCellularComponenttransmembrane transporter complex

NDUFC2-KCTD14 CACNA1E PKD2L1 NDUFC2 SLC26A6 SCN8A

9.55e-04523466GO:1902495
GeneOntologyCellularComponenttransporter complex

NDUFC2-KCTD14 CACNA1E PKD2L1 NDUFC2 SLC26A6 SCN8A

1.24e-03550466GO:1990351
GeneOntologyCellularComponentapical part of cell

SLC26A3 SLC7A13 SLC26A7 F2RL2 SLC26A6 SLC26A4

1.80e-03592466GO:0045177
DomainSLC26A

SLC26A3 SLC26A7 SLC26A6 SLC26A4

5.57e-0910444PS01130
DomainSTAS

SLC26A3 SLC26A7 SLC26A6 SLC26A4

8.73e-0911444PS50801
DomainSLC26A/SulP_fam

SLC26A3 SLC26A7 SLC26A6 SLC26A4

8.73e-0911444IPR001902
DomainSTAS_dom

SLC26A3 SLC26A7 SLC26A6 SLC26A4

8.73e-0911444IPR002645
Domain-

SLC26A3 SLC26A7 SLC26A6 SLC26A4

8.73e-09114443.30.750.24
DomainSLC26A/SulP_dom

SLC26A3 SLC26A7 SLC26A6 SLC26A4

8.73e-0911444IPR011547
DomainSulfate_transp

SLC26A3 SLC26A7 SLC26A6 SLC26A4

8.73e-0911444PF00916
DomainSTAS

SLC26A3 SLC26A7 SLC26A6 SLC26A4

8.73e-0911444PF01740
DomainS04_transporter_CS

SLC26A3 SLC26A6 SLC26A4

4.24e-077443IPR018045
DomainNDUF_C2

NDUFC2-KCTD14 NDUFC2

5.42e-062442PF06374
DomainAlg10

ALG10B ALG10

5.42e-062442IPR016900
DomainNADH-UbQ_OxRdtase_b14.5b_su

NDUFC2-KCTD14 NDUFC2

5.42e-062442IPR009423
DomainDIE2_ALG10

ALG10B ALG10

5.42e-062442PF04922
DomainOtopetrin

OTOP2 OTOP3

1.62e-053442PF03189
DomainFatty_acid_desaturase

FADS2 FADS3

1.62e-053442IPR012171
DomainOtopetrin

OTOP2 OTOP3

1.62e-053442IPR004878
DomainPKD_2

PKD2L1 PKDREJ

5.40e-055442IPR003915
DomainFA_desaturase_dom

FADS2 FADS3

1.51e-048442IPR005804
DomainFA_desaturase

FADS2 FADS3

1.51e-048442PF00487
DomainPKD1_2_channel

PKD2L1 PKDREJ

2.94e-0411442IPR013122
DomainPKD_channel

PKD2L1 PKDREJ

2.94e-0411442PF08016
DomainCYTOCHROME_B5_2

FADS2 FADS3

4.16e-0413442PS50255
DomainCYTOCHROME_B5_1

FADS2 FADS3

4.16e-0413442PS00191
DomainCyt-b5

FADS2 FADS3

4.85e-0414442PF00173
DomainCyt_B5-like_heme/steroid-bd

FADS2 FADS3

4.85e-0414442IPR001199
DomainCyt-b5

FADS2 FADS3

4.85e-0414442SM01117
Domain-

FADS2 FADS3

4.85e-04144423.10.120.10
Domain-

PLXNA3 RASA2

6.37e-04164421.10.506.10
DomainRasGAP_dom

PLXNA3 RASA2

8.10e-0418442IPR001936
DomainChannel_four-helix_dom

CACNA1E SCN8A

7.97e-0357442IPR027359
Domain-

CACNA1E SCN8A

7.97e-03574421.20.120.350
PathwayREACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS

SLC26A3 SLC26A7 SLC26A6 SLC26A4

1.56e-099284M27344
PathwayREACTOME_MULTIFUNCTIONAL_ANION_EXCHANGERS

SLC26A3 SLC26A7 SLC26A6 SLC26A4

1.56e-099284MM15084
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC26A3 SLC26A7 SLC26A6 SLC26A4

5.79e-05108284M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC26A3 SLC26A7 SLC26A6 SLC26A4

6.00e-05109284MM15074
PathwayKEGG_MEDICUS_REFERENCE_N_GLYCAN_PRECURSOR_BIOSYNTHESIS_ALG6_TO_OST

ALG10B ALG10

2.07e-0411282M47614
PathwayWP_OMEGA9_FATTY_ACID_SYNTHESIS

ACSL3 FADS2

3.41e-0414282MM15840
PathwayWP_OMEGA9_FATTY_ACID_SYNTHESIS

ACSL3 FADS2

3.41e-0414282M39780
PathwayWP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS

ACSL3 FADS2

3.93e-0415282M39789
PathwayWP_OMEGA3_OMEGA6_FATTY_ACID_SYNTHESIS

ACSL3 FADS2

4.49e-0416282MM15813
PathwayREACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI

PIGV PIGM

5.08e-0417282MM14621
PathwayREACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI

PIGV PIGM

5.71e-0418282M1093
PathwayKEGG_MEDICUS_REFERENCE_GPI_ANCHOR_BIOSYNTHESIS

PIGV PIGM

1.02e-0324282M47625
PathwayKEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI_ANCHOR_BIOSYNTHESIS

PIGV PIGM

1.11e-0325282M13265
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A3 SLC26A7 SLC26A6 SLC26A4

1.18e-03238284MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC26A3 SLC26A7 SLC26A6 SLC26A4

1.39e-03249284M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC26A3 ABCA3 SLC26A7 SLC26A6 SLC26A4 ANO8

1.88e-03681286MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC26A3 ABCA3 SLC26A7 SLC26A6 SLC26A4 ANO8

2.78e-03736286M27287
Pubmed

Physiological roles and regulation of mammalian sulfate transporters.

SLC26A3 SLC26A7 SLC26A6 SLC26A4

3.36e-10946411581495
Pubmed

N-glycosylation and topology of the human SLC26 family of anion transport membrane proteins.

SLC26A3 SLC26A7 SLC26A6 SLC26A4

5.59e-101046424647542
Pubmed

Mapping of five new putative anion transporter genes in human and characterization of SLC26A6, a candidate gene for pancreatic anion exchanger.

SLC26A3 SLC26A6 SLC26A4

4.32e-08646311087667
Pubmed

Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9.

SLC26A3 SLC26A7 SLC26A4

4.32e-08646311834742
Pubmed

Placental, renal, and ileal sulfate transporter gene expression in mouse gestation.

SLC26A3 SLC26A7 SLC26A6

1.81e-07946322674389
Pubmed

The Slc26a4 transporter functions as an electroneutral Cl-/I-/HCO3- exchanger: role of Slc26a4 and Slc26a6 in I- and HCO3- secretion and in regulation of CFTR in the parotid duct.

SLC26A6 SLC26A4

1.71e-06246218565999
Pubmed

Loss of the anion exchanger DRA (Slc26a3), or PAT1 (Slc26a6), alters sulfate transport by the distal ileum and overall sulfate homeostasis.

SLC26A3 SLC26A6

1.71e-06246228526688
Pubmed

The iodide transporter Slc26a7 impacts thyroid function more strongly than Slc26a4 in mice.

SLC26A7 SLC26A4

1.71e-06246235788623
Pubmed

Identification of a chloride-formate exchanger expressed on the brush border membrane of renal proximal tubule cells.

SLC26A6 SLC26A4

1.71e-06246211459928
Pubmed

Induction of enteric oxalate secretion by Oxalobacter formigenes in mice does not require the presence of either apical oxalate transport proteins Slc26A3 or Slc26A6.

SLC26A3 SLC26A6

1.71e-06246231201468
Pubmed

Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.

SLC26A3 SLC26A6

1.71e-06246230118583
Pubmed

Slc26a3/Dra and Slc26a6 in Murine Ameloblasts.

SLC26A3 SLC26A6

1.71e-06246226394631
Pubmed

Expression profiling of SCN8A and NDUFC2 genes in colorectal carcinoma.

NDUFC2 SCN8A

1.71e-06246225804238
Pubmed

Association of the FADS gene cluster with coronary artery disease and plasma lipid concentrations in the northern Chinese Han population.

FADS2 FADS3

1.71e-06246228237083
Pubmed

Coupling modes and stoichiometry of Cl-/HCO3- exchange by slc26a3 and slc26a6.

SLC26A3 SLC26A6

1.71e-06246216606687
Pubmed

Sulfate secretion and chloride absorption are mediated by the anion exchanger DRA (Slc26a3) in the mouse cecum.

SLC26A3 SLC26A6

1.71e-06246223660504
Pubmed

SLC26A6 and SLC26A7 anion exchangers have a distinct distribution in human kidney.

SLC26A7 SLC26A6

1.71e-06246215956810
Pubmed

NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.

NDUFC2-KCTD14 NDUFC2

1.71e-06246237506315
Pubmed

Involvement of Cl(-)/HCO3(-) exchanger SLC26A3 and SLC26A6 in preimplantation embryo cleavage.

SLC26A3 SLC26A6

1.71e-06246227346053
Pubmed

Effect of Slc26a6 deletion on apical Cl-/HCO3- exchanger activity and cAMP-stimulated bicarbonate secretion in pancreatic duct.

SLC26A3 SLC26A6

1.71e-06246216901991
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

NT5C2 CERS2 ACSL3 FADS2 NDUFC2-KCTD14 FADS3 NDUFC2 TMEM181 ABHD16A LPCAT3 TM9SF1

2.23e-061451461130550785
Pubmed

Functional genetic analysis of mouse chromosome 11.

ALG10B ALG10 SCN8A

3.76e-062346312955145
Pubmed

Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies.

FADS2 FADS3

5.13e-06346236652541
Pubmed

Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy.

OTOP2 OTOP3

5.13e-06346229040572
Pubmed

Deletion of Slc26a6 alters the stoichiometry of apical Cl-/HCO-3 exchange in mouse pancreatic duct.

SLC26A3 SLC26A6

5.13e-06346222895259
Pubmed

Association of polyunsaturated fatty acids in breast milk with fatty acid desaturase gene polymorphisms among Chinese lactating mothers.

FADS2 FADS3

5.13e-06346227269715
Pubmed

Decreased expression of Slc26a4 (Pendrin) and Slc26a7 in the kidneys of carbonic anhydrase II-deficient mice.

SLC26A7 SLC26A4

5.13e-06346218209476
Pubmed

Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).

FADS2 FADS3

5.13e-06346222877655
Pubmed

Native and recombinant Slc26a3 (downregulated in adenoma, Dra) do not exhibit properties of 2Cl-/1HCO3- exchange.

SLC26A3 SLC26A6

5.13e-06346221068358
Pubmed

A point mutation in the gene for asparagine-linked glycosylation 10B (Alg10b) causes nonsyndromic hearing impairment in mice (Mus musculus).

ALG10B ALG10

5.13e-06346224303013
Pubmed

PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum.

SLC26A3 SLC26A6

5.13e-06346217170027
Pubmed

Functional activity of Pat-1 (Slc26a6) Cl(−)/HCO₃(−) exchange in the lower villus epithelium of murine duodenum.

SLC26A3 SLC26A6

5.13e-06346220969732
Pubmed

An evolutionarily conserved gene family encodes proton-selective ion channels.

OTOP2 OTOP3

5.13e-06346229371428
Pubmed

FADS gene polymorphisms in Koreans: association with ω6 polyunsaturated fatty acids in serum phospholipids, lipid peroxides, and coronary artery disease.

FADS2 FADS3

5.13e-06346221040914
Pubmed

Molecular analysis of human solute carrier SLC26 anion transporter disease-causing mutations using 3-dimensional homology modeling.

SLC26A3 SLC26A4

5.13e-06346228941661
Pubmed

SLC26A Gene Family Participate in pH Regulation during Enamel Maturation.

SLC26A7 SLC26A6

5.13e-06346226671068
Pubmed

Genetic variants in desaturase gene, erythrocyte fatty acids, and risk for type 2 diabetes in Chinese Hans.

FADS2 FADS3

5.13e-06346224985009
Pubmed

cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family.

FADS2 FADS3

5.13e-06346210860662
Pubmed

Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2).

PKD2L1 PKDREJ

5.13e-06346210602361
Pubmed

The switch of intestinal Slc26 exchangers from anion absorptive to HCOFormula secretory mode is dependent on CFTR anion channel function.

SLC26A3 SLC26A6

1.03e-05446220164375
Pubmed

TEAD1, MYO7A and NDUFC2 are novel functional genes associated with glucose metabolism in BXD recombinant inbred population.

NDUFC2-KCTD14 NDUFC2

1.03e-05446238385898
Pubmed

The IKr drug response is modulated by KCR1 in transfected cardiac and noncardiac cell lines.

ALG10B ALG10

1.03e-05446214525949
Pubmed

Down-regulated in adenoma Cl/HCO3 exchanger couples with Na/H exchanger 3 for NaCl absorption in murine small intestine.

SLC26A3 SLC26A6

1.03e-05446218930060
Pubmed

Role of down-regulated in adenoma anion exchanger in HCO3- secretion across murine duodenum.

SLC26A3 SLC26A6

1.03e-05446219121635
Pubmed

Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study.

FADS2 FADS3

1.03e-05446219148276
Pubmed

Participation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitation.

SLC26A3 SLC26A6

1.03e-05446221976599
Pubmed

FADS genetic variants and omega-6 polyunsaturated fatty acid metabolism in a homogeneous island population.

FADS2 FADS3

1.03e-05446220562440
Pubmed

Polycystin channels and kidney disease.

PKD2L1 PKDREJ

1.71e-05546211698076
Pubmed

Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice.

OTOP2 OTOP3

1.71e-05546212588793
Pubmed

The distinct roles of anion transporters Slc26a3 (DRA) and Slc26a6 (PAT-1) in fluid and electrolyte absorption in the murine small intestine.

SLC26A3 SLC26A6

1.71e-05546224233434
Pubmed

Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.

SLC26A3 SLC26A6

2.56e-05646224018950
Pubmed

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

FADS2 PKD2L1 FADS3

3.59e-054846322359512
Pubmed

Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos.

NDUFC2-KCTD14 NDUFC2

4.77e-0584629425147
Pubmed

Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.

OTOP2 OTOP3

4.77e-05846212651873
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

CERS2 ACSL3 FADS2 TMEM181 LPCAT3 TM9SF1

4.87e-0549946622810586
Pubmed

Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.

FADS2 FADS3

6.12e-05946225194280
Pubmed

Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium.

FADS2 PKD2L1 FADS3

7.03e-056046323362303
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

PKD2L1 PKDREJ

7.65e-051046216805797
Pubmed

A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library.

CACNA1E TPRA1

1.12e-04124629776767
Pubmed

Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders.

OTOP2 OTOP3 SCN8A

1.21e-047246325917818
Pubmed

Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes.

FADS2 FADS3

1.54e-041446223378610
Pubmed

Discovery and refinement of loci associated with lipid levels.

CERS2 FADS2 FADS3 PIGV

1.76e-0421146424097068
Pubmed

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.

FADS2 MARVELD3 FADS3 RASA2

2.25e-0422546423341629
Pubmed

Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis.

PIGV PIGM

2.30e-041746211102867
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

CERS2 TMEM62 ABCA3 G6PC3 ANO8 PIGM

3.00e-0469746628298427
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

CERS2 ACSL3 FADS2 LPCAT3 ANO8

3.76e-0446846531056421
Pubmed

Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy.

FADS2 FADS3 LPCAT3

3.80e-0410646333087821
Pubmed

Genetics of rheumatoid arthritis contributes to biology and drug discovery.

FADS2 FADS3 ANO8

4.46e-0411246324390342
Pubmed

Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A.

FADS2 SCN8A

6.33e-042846219352218
Pubmed

Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2.

CERS2 FADS2

6.79e-042946238485951
Pubmed

Genetic loci associated with lipid concentrations and cardiovascular risk factors in the Korean population.

FADS2 FADS3

6.79e-042946220972250
Pubmed

Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium.

FADS2 FADS3

6.79e-042946221829377
Pubmed

High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility.

LAMB4 MFSD6

7.27e-043046219401682
Pubmed

Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1α-glycolysis axis.

NDUFC2-KCTD14 NDUFC2

7.77e-043146236127325
Pubmed

Defining the membrane proteome of NK cells.

CERS2 ACSL3 FADS2 G6PC3 LPCAT3 MFSD6 VPS50

8.06e-04116846719946888
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

PKD2L1 PKDREJ

8.80e-043346219834762
Pubmed

Region-specific expression of mitochondrial complex I genes during murine brain development.

NDUFC2-KCTD14 NDUFC2

9.35e-043446221556144
Pubmed

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

FADS2 FADS3

9.35e-043446219060911
Pubmed

Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8.

FADS2 G6PC3

1.05e-033646238070861
Pubmed

WDFY4 is required for cross-presentation in response to viral and tumor antigens.

NT5C2 CERS2 VPS50

1.17e-0315646330409884
InteractionPOMK interactions

CERS2 PKDCC ACSL3 LPCAT3 TM9SF1 ALG10 PIGM

2.16e-06271457int:POMK
InteractionTSPAN15 interactions

CERS2 ACSL3 NDUFC2 TMEM181 LPCAT3 TM9SF1 ALG10

2.44e-06276457int:TSPAN15
InteractionUPK1A interactions

TMEM62 ABCA3 LPCAT3 ALG10 PIGM

2.05e-05150455int:UPK1A
InteractionKLRC3 interactions

TMEM62 TMEM181 PIGM

3.65e-0529453int:KLRC3
InteractionPTH1R interactions

ABCA3 LPCAT3 ALG10 PIGM

4.41e-0588454int:PTH1R
InteractionTTYH1 interactions

CERS2 TMEM62 ABCA3 LPCAT3 ALG10 PIGM

5.17e-05300456int:TTYH1
InteractionAQP7 interactions

ABHD16A MFSD6

7.27e-056452int:AQP7
InteractionKLRC2 interactions

TMEM62 ABCA3 PIGM

1.48e-0446453int:KLRC2
InteractionSPPL2B interactions

NDUFC2 TMEM181 IGSF3 ALG10 PIGM

1.66e-04233455int:SPPL2B
InteractionCD79A interactions

OTOP2 SLC26A6 ALG10B ALG10 MFSD6

2.86e-04262455int:CD79A
InteractionSLC6A8 interactions

FADS2 TPRA1 G6PC3 SLC26A6

3.05e-04145454int:SLC6A8
InteractionSHISAL1 interactions

ALG10B ALG10 MFSD6

3.26e-0460453int:SHISAL1
InteractionC5AR1 interactions

CERS2 TM9SF1 ALG10 PIGM

3.83e-04154454int:C5AR1
InteractionLPAR6 interactions

NDUFC2 LPCAT3 ALG10

4.71e-0468453int:LPAR6
InteractionCRELD1 interactions

NDUFC2 LPCAT3 ALG10B ALG10

4.75e-04163454int:CRELD1
InteractionTACR1 interactions

CERS2 NDUFC2 LPCAT3

4.92e-0469453int:TACR1
Cytoband7q31

LAMB4 SLC26A3 SLC26A4

2.71e-06274637q31
Cytoband11q14.1

NDUFC2-KCTD14 NDUFC2

8.24e-044246211q14.1
Cytoband17q25.1

OTOP2 OTOP3

3.03e-038146217q25.1
CytobandEnsembl 112 genes in cytogenetic band chr17q25

OTOP2 C1QTNF1 OTOP3

3.63e-03307463chr17q25
CytobandEnsembl 112 genes in cytogenetic band chr11q12

FADS2 FADS3 FADS2B

5.03e-03345463chr11q12
GeneFamilyAlpha-1,2-glucosyltransferases

ALG10B ALG10

3.43e-062342448
GeneFamilySolute carriers

SLC26A3 SLC7A13 SLC26A7 SLC38A6 SLC26A6 SLC26A4

8.39e-05395346752
GeneFamilyFatty acid desaturases

FADS2 FADS3

9.54e-058342553
GeneFamilyDolichyl D-mannosyl phosphate dependent mannosyltransferases|Phosphatidylinositol glycan anchor biosynthesis

PIGV PIGM

1.23e-049342430
GeneFamilyGlycosyl transferases group 1 domain containing|Phosphatidylinositol glycan anchor biosynthesis

PIGV PIGM

7.05e-0421342680
CoexpressionGSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_UP

CERS2 FADS2 FADS3 F2RL2 LPCAT3 ANO8

1.33e-06200466M6710
Diseaselipid metabolism disorder (implicated_via_orthology)

FADS2 FADS3 FADS2B

1.49e-0615453DOID:3146 (implicated_via_orthology)
DiseaseLong Qt Syndrome 2

ALG10B ALG10

6.82e-063452C3150943
Diseasenonsyndromic deafness (implicated_via_orthology)

ALG10B ALG10

3.40e-056452DOID:0050563 (implicated_via_orthology)
Disease1-(1-enyl-stearoyl)-2-arachidonoyl-GPC (P-18:0/20:4) measurement

FADS2 PKD2L1

3.40e-056452EFO_0800394
Diseaselevel of Phosphatidylcholine (16:0_18:0) in blood serum

FADS2 FADS3

3.40e-056452OBA_2045069
Diseaselevel of Phosphatidylcholine (16:1_20:4) in blood serum

FADS2 FADS3

3.40e-056452OBA_2045084
Diseaselevel of Phosphatidylcholine (O-18:2_18:1) in blood serum

FADS2 FADS3

4.75e-057452OBA_2045133
Diseaselysophosphatidylcholine 22:4 measurement

FADS2 FADS3

4.75e-057452EFO_0021461
Diseasephosphatidylcholine 35:5 measurement

FADS2 FADS3

4.75e-057452EFO_0021472
Diseaselevel of Phosphatidylethanolamine (O-18:1_18:2) in blood serum

FADS2 FADS3

6.33e-058452OBA_2045147
Diseasefatty acid desaturase enzyme activity measurement

FADS2 PKD2L1

6.33e-058452EFO_0009791
Diseasediglyceride measurement

FADS2 PKD2L1 FADS3

6.56e-0551453EFO_0010223
Diseasephosphatidylcholine 39:5 measurement

FADS2 FADS3

8.13e-059452EFO_0021476
Diseaselevel of Phosphatidylcholine (18:2_20:1) in blood serum

FADS2 FADS3

8.13e-059452OBA_2045107
Diseaselevel of Phosphatidylcholine (O-18:0_20:4) in blood serum

FADS2 FADS3

8.13e-059452OBA_2045127
Diseaselevel of Phosphatidylcholine (O-18:1_18:2) in blood serum

FADS2 FADS3

8.13e-059452OBA_2045129
Diseaselevel of Phosphatidylcholine (O-18:1_20:3) in blood serum

FADS2 FADS3

8.13e-059452OBA_2045130
Diseaselevel of Phosphatidylcholine (16:0_20:5) in blood serum

FADS2 FADS3

8.13e-059452OBA_2045077
Diseaselevel of Phosphatidylcholine (18:0_20:5) in blood serum

FADS2 FADS3

8.13e-059452OBA_2045095
Diseaselevel of Phosphatidylethanolamine (O-18:1_20:4) in blood serum

FADS2 FADS3

1.02e-0410452OBA_2045148
Disease1-(1-enyl-palmitoyl)-2-palmitoleoyl-GPC (P-16:0/16:1) measurement

FADS2 PKD2L1

1.02e-0410452EFO_0800464
Diseasecholesteryl ester 22:4 measurement

FADS2 FADS3

1.02e-0410452EFO_0021443
Diseasecholesteryl ester 22:5 measurement

FADS2 FADS3

1.02e-0410452EFO_0021444
Diseaselysophosphatidylcholine measurement

FADS2 PKD2L1 FADS3

1.18e-0462453EFO_0010224
Diseaselevel of Phosphatidylcholine (O-16:1_20:4) in blood serum

FADS2 FADS3

1.24e-0411452OBA_2045123
Diseaselysophosphatidylcholine 20:2 measurement

FADS2 FADS3

1.24e-0411452EFO_0021458
Diseasecholesteryl ester 20:2 measurement

FADS2 FADS3

1.49e-0412452EFO_0021440
Diseaselevel of Phosphatidylcholine (O-16:0_20:4) in blood serum

FADS2 FADS3

1.76e-0413452OBA_2045116
Diseaselevel of Phosphatidylcholine (16:0_18:3) in blood serum

FADS2 FADS3

1.76e-0413452OBA_2045072
Diseaselevel of Phosphatidylcholine (16:1_18:1) in blood serum

FADS2 PKD2L1

1.76e-0413452OBA_2045082
Diseaselevel of Phosphatidylcholine (18:1_20:2) in blood serum

FADS2 FADS3

2.05e-0414452OBA_2045102
Diseasediacylglycerol 38:4 measurement

FADS2 FADS3

2.05e-0414452EFO_0020066
Diseaselevel of Phosphatidylcholine (O-18:1_20:4) in blood serum

FADS2 FADS3

2.36e-0415452OBA_2045131
Diseasecis/trans-18:2 fatty acid measurement, trans fatty acid measurement

FADS2 FADS3

2.36e-0415452EFO_0006821, EFO_0006824
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement

FADS2 FADS3

2.36e-0415452EFO_0800508
Diseasephosphatidylcholine 36:4 measurement

FADS2 FADS3

3.43e-0418452EFO_0010382
Diseaselevel of Phosphatidylcholine (20:4_0:0) in blood serum

FADS2 FADS3

3.43e-0418452OBA_2045110
Diseaselevel of Phosphatidylcholine (16:0_22:5) in blood serum

FADS2 FADS3

3.43e-0418452OBA_2045079
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

FADS2 FADS3

3.83e-0419452OBA_2045199
Diseasediacylglycerol 38:5 measurement

FADS2 FADS3

3.83e-0419452EFO_0020067
Diseasediacylglycerol 38:3 measurement

FADS2 FADS3

3.83e-0419452EFO_0020065
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

FADS2 FADS3

4.69e-0421452OBA_2045104
Diseaselevel of Phosphatidylinositol (18:0_18:2) in blood serum

FADS2 FADS3

4.69e-0421452OBA_2045156
Diseasesaturated fatty acids to total fatty acids percentage

FADS2 PKD2L1

4.69e-0421452EFO_0022305
Diseaselevel of Phosphatidylcholine (16:0_20:4) in blood serum

FADS2 FADS3

4.69e-0421452OBA_2045076
Diseaselevel of Phosphatidylcholine (16:1_18:2) in blood serum

FADS2 PKD2L1

4.69e-0421452OBA_2045083
Diseaselevel of Phosphatidylinositol (18:0_20:4) in blood serum

FADS2 FADS3

5.64e-0423452OBA_2045158
Diseasephosphatidylserines measurement

FADS2 FADS3

5.64e-0423452EFO_0020049
Diseasealpha-linolenic acid measurement

FADS2 FADS3

6.67e-0425452EFO_0007759
Diseaselysophosphatidylethanolamine 18:2 measurement

FADS2 FADS3

7.22e-0426452EFO_0010369
Diseaselevel of Phosphatidylcholine (17:0_20:4) in blood serum

FADS2 FADS3

7.22e-0426452OBA_2045087
Diseasedocosapentaenoic acid measurement

FADS2 FADS3

7.79e-0427452EFO_0006809
Diseaselevel of Phosphatidylethanolamine (18:0_18:2) in blood serum

FADS2 FADS3

8.38e-0428452OBA_2045139
Diseasesphingomyelin measurement

PKDCC FADS2 FADS3 SCN8A

8.48e-04278454EFO_0010118
Diseaselysophosphatidylethanolamine 20:4 measurement

FADS2 FADS3

8.99e-0429452EFO_0010370
Diseasephosphatidylcholine measurement

FADS2 PKD2L1 FADS3 LPCAT3

9.18e-04284454EFO_0010226
Diseaseeicosapentaenoic acid measurement

FADS2 FADS3

1.03e-0331452EFO_0007760
Diseaselevel of Sterol ester (27:1/20:4) in blood serum

FADS2 FADS3

1.03e-0331452OBA_2045198
Diseaselevel of Phosphatidylcholine (18:0_20:4) in blood serum

FADS2 FADS3

1.03e-0331452OBA_2045094
Diseaselysophosphatidylcholine 20:4 measurement

FADS2 FADS3

1.10e-0332452EFO_0010363
Diseasecholesteryl ester 22:6 measurement

FADS2 FADS3

1.10e-0332452EFO_0010350
Diseasephosphatidylcholine 38:5 measurement

FADS2 FADS3

1.17e-0333452EFO_0010387
Diseasesystolic blood pressure, body mass index

NT5C2 TPRA1

1.24e-0334452EFO_0004340, EFO_0006335
Diseasephosphatidylcholine 38:2 measurement

FADS2 FADS3

1.31e-0335452EFO_0010384
Diseasecholesteryl ester 16:0 measurement

FADS2 FADS3

1.39e-0336452EFO_0010341
Diseasetriacylglycerol 56:8 measurement

FADS2 FADS3

1.39e-0336452EFO_0010435

Protein segments in the cluster

PeptideGeneStartEntry
YFLYATYGTLAFLFS

TMEM62

591

Q0P6H9
IFYVVYFVVFPFFFV

CACNA1E

1401

Q15878
YAASFINLLYYPFSY

NT5C2

461

P49902
PFAFFYLYRKGYLSL

ABHD16A

76

O95870
AFGGFLYFFTYIPYF

ABCA3

376

Q99758
LYFFTYIPYFFVAPR

ABCA3

381

Q99758
TLAVFPTLYFFNFLY

ALG10B

136

Q5I7T1
PTLYFFNFLYYTEAG

ALG10B

141

Q5I7T1
YPLELYPAFFGYYFF

CERS2

291

Q96G23
FVNSYLSLFYIGFYL

ANO8

446

Q9HCE9
FYFEIPRTFQYLSFY

RASA2

91

Q15283
SYYIRFFITYIPFYG

FADS2

301

O95864
YFTLYYAFYVAVLPT

OTOP3

371

Q7RTS5
KILFLFYFPAAYYAS

G6PC3

36

Q9BUM1
LSLYPAFDIYYIYGF

PLXNA3

216

P51805
YIYGFVSASFVYFLT

PLXNA3

226

P51805
YKDLEPFTYFFYLVF

GPR171

11

O14626
LLYITAFFFAGYYLV

NDUFC2

61

O95298
GYPFALFYRHYLFYK

LPCAT3

51

Q6P1A2
SKVFYFFFYSAYGSL

MFSD6

71

Q6ZSS7
FFFYSAYGSLYPLLP

MFSD6

76

Q6ZSS7
YYFISLAFFGFLIPF

F2RL2

261

O00254
FYLYPFNIEYSLFAS

OTOP2

241

Q7RTS6
VSSFYIYFITFGLYY

FADS2B

341

A8MWK0
SNDALFYFVFFYPFP

IGSF3

1121

O75054
FYFVFFYPFPIFGIL

IGSF3

1126

O75054
FTGKFYCYVPGLYFF

C1QTNF1

181

Q9BXJ1
GYIPALYFYFHYLSA

MARVELD3

316

Q96A59
PGYFFAPLNFYLYEA

LAMB4

541

A4D0S4
FYLKSSYIIYFEPLF

CXorf1

6

O96002
ASFYARFFLSYLPFY

FADS3

301

Q9Y5Q0
YNAYRFFFTYLLPHS

PKDCC

341

Q504Y2
FFNYLYVLSFYGSSL

PTCHD1

411

Q96NR3
FGLYSSFYPVFIYFL

SLC26A6

121

Q9BXS9
SSFFIVFYGLTYGYD

PKDREJ

1591

Q9NTG1
YFISALFGYLTFYDK

SLC38A6

296

Q8IZM9
LYASFFPAIIYLFFG

SLC26A3

106

P40879
YYFSYPLFVGFALLR

SPAST

51

Q9UBP0
TLAVFPTLYFFNFLY

ALG10

136

Q5BKT4
PTLYFFNFLYYTEAG

ALG10

141

Q5BKT4
SLYTILTYIPFYFFS

ACSL3

31

O95573
FTLGLPFALFQYYAY

PIGV

246

Q9NUD9
QLFDYYLYAIYTFFG

VPS50

641

Q96JG6
LYFSFFAPLIYVAFL

TPRA1

266

Q86W33
GLYSAFFPILTYFIF

SLC26A4

116

O43511
AEFLSFYGLLNFYLY

TMEM181

536

Q9P2C4
FYGLLNFYLYTLAFV

TMEM181

541

Q9P2C4
YIYFVIFIIFGSFFT

SCN8A

1441

Q9UQD0
YYFLKRYFGSTVAFL

SLC7A13

81

Q8TCU3
LGPAYFVTYVFFVFF

PKD2L1

536

Q9P0L9
LLYITAFFFAGYYLV

NDUFC2-KCTD14

61

E9PQ53
ISGPLGFFYIYAYVF

SLC26A7

206

Q8TE54
LTFFALSFGFYYEYG

PIGM

236

Q9H3S5
STGLFIFLYSVFYYA

TM9SF1

541

O15321