Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR3

1.23e-044912GO:0005219
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR3

3.04e-046912GO:0048763
GeneOntologyMolecularFunctioncalcium channel activity

TRPM5 CATSPER2 TRPM1 RYR1 RYR3

3.10e-04129915GO:0005262
GeneOntologyMolecularFunctionligand-gated calcium channel activity

TRPM5 RYR1 RYR3

3.75e-0431913GO:0099604
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

TRPM5 CATSPER2 TRPM1 RYR1 RYR3

6.38e-04151915GO:0015085
GeneOntologyBiologicalProcessneuroblast division

NUMBL AKNA FGFR2

4.04e-0516883GO:0055057
GeneOntologyBiologicalProcessmicrotubule-based protein transport

MYO5A CAMSAP3 CEP131

4.89e-0517883GO:0099118
GeneOntologyBiologicalProcessprotein transport along microtubule

MYO5A CAMSAP3 CEP131

4.89e-0517883GO:0098840
GeneOntologyBiologicalProcessneuroblast division in subventricular zone

NUMBL AKNA

5.38e-053882GO:0021849
DomainRyanrecept_TM4-6

RYR1 RYR3

7.18e-053922IPR009460
DomainRyR

RYR1 RYR3

7.18e-053922PF02026
DomainRyanodine_rcpt

RYR1 RYR3

7.18e-053922IPR003032
DomainRR_TM4-6

RYR1 RYR3

7.18e-053922PF06459
DomainRyan_recept

RYR1 RYR3

7.18e-053922IPR013333
DomainIon_trans_dom

TRPM5 CATSPER2 TRPM1 RYR1 RYR3

2.50e-04114925IPR005821
DomainIon_trans

TRPM5 CATSPER2 TRPM1 RYR1 RYR3

2.50e-04114925PF00520
DomainRIH_assoc

RYR1 RYR3

3.55e-046922PF08454
DomainRIH_assoc-dom

RYR1 RYR3

3.55e-046922IPR013662
DomainRIH_dom

RYR1 RYR3

3.55e-046922IPR000699
DomainIns145_P3_rcpt

RYR1 RYR3

3.55e-046922IPR014821
DomainRyanodine_recept-rel

RYR1 RYR3

3.55e-046922IPR015925
Domain-

RYR1 RYR3

3.55e-0469221.25.10.30
DomainRYDR_ITPR

RYR1 RYR3

3.55e-046922PF01365
DomainIns145_P3_rec

RYR1 RYR3

3.55e-046922PF08709
DomainShisa

SHISA9 SHISA3

8.45e-049922PF13908
DomainShisa

SHISA9 SHISA3

8.45e-049922IPR026910
DomainMIR

RYR1 RYR3

1.05e-0310922PS50919
DomainMIR

RYR1 RYR3

1.05e-0310922PF02815
DomainMIR

RYR1 RYR3

1.05e-0310922SM00472
DomainMIR_motif

RYR1 RYR3

1.05e-0310922IPR016093
DomainSulfatase_CS

ARSJ ARSI

2.75e-0316922IPR024607
DomainSULFATASE_1

ARSJ ARSI

3.11e-0317922PS00523
DomainSULFATASE_2

ARSJ ARSI

3.11e-0317922PS00149
DomainSulfatase

ARSJ ARSI

3.49e-0318922PF00884
DomainIntegrin_alpha-2

ITGA11 ITGA7

3.49e-0318922IPR013649
DomainIntegrin_alpha2

ITGA11 ITGA7

3.49e-0318922PF08441
DomainIntegrin_alpha

ITGA11 ITGA7

3.49e-0318922IPR000413
DomainSulfatase_N

ARSJ ARSI

3.49e-0318922IPR000917
DomainINTEGRIN_ALPHA

ITGA11 ITGA7

3.49e-0318922PS00242
DomainInt_alpha_beta-p

ITGA11 ITGA7

3.89e-0319922IPR013519
DomainInt_alpha

ITGA11 ITGA7

3.89e-0319922SM00191
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PPP1R26 ARSJ KANSL1 RPAP1 ESYT1 NLRX1 TMC6 AKNA SDF4 TSC2 CEP131 FGFR2 PC RYR1 FANCA

2.06e-071105921535748872
Pubmed

Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.

RYR1 RYR3

6.92e-06292212565913
Pubmed

Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.

RYR1 RYR3

6.92e-0629229489997
Pubmed

Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.

RYR1 RYR3

6.92e-0629229192302
Pubmed

Elevated Thyroid Autoantibodies Aggravate Stroke Severity in Euthyroidism with Acute Ischemic Stroke.

TPO TG

6.92e-06292235256895
Pubmed

The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.

RYR1 RYR3

6.92e-06292212640042
Pubmed

Myosin Va and Endoplasmic Reticulum Calcium Channel Complex Regulates Membrane Export during Axon Guidance.

MYO5A RYR3

6.92e-06292227134178
Pubmed

The prevalence of iodine deficiency, serum thyroglobulin, anti-thyroglobulin and thyroid peroxidase antibody levels in the urban areas of Kayseri, Central Anatolia.

TPO TG

6.92e-06292219194833
Pubmed

Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.

RYR1 RYR3

6.92e-0629227556644
Pubmed

Lack of a role for cross-reacting anti-thyroid antibodies in chronic idiopathic urticaria.

TPO TG

6.92e-06292220182447
Pubmed

Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.

RYR1 RYR3

6.92e-06292214592949
Pubmed

Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.

LRP1 ADAM10

6.92e-06292227503326
Pubmed

Anti-Helicobacter Pylori, anti-thyroid peroxidase, anti-thyroglobulin and anti-gastric parietal cells antibodies in Czech population.

TPO TG

6.92e-06292218271683
Pubmed

Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.

RYR1 RYR3

6.92e-06292215894801
Pubmed

Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.

RYR1 RYR3

6.92e-0629229799464
Pubmed

Mutations in the genes for thyroglobulin and thyroid peroxidase cause thyroid dyshormonogenesis and autosomal-recessive intellectual disability.

TPO TG

6.92e-06292227305979
Pubmed

Expression of the Na+/I- symporter gene in human thyroid tumors: a comparison study with other thyroid-specific genes.

TPO TG

6.92e-06292210487692
Pubmed

Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.

RYR1 RYR3

6.92e-0629229817784
Pubmed

Expression and distribution of trophoblast glycoprotein in the mouse retina.

TRPM1 TPBG

6.92e-06292231891182
Pubmed

Increased Prevalence of TG and TPO Mutations in Sudanese Children With Congenital Hypothyroidism.

TPO TG

6.92e-06292231867598
Pubmed

Antibodies to thyroid peroxidase arise spontaneously with age in NOD.H-2h4 mice and appear after thyroglobulin antibodies.

TPO TG

6.92e-06292220573721
Pubmed

Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.

RYR1 RYR3

6.92e-06292217118445
Pubmed

Evidence of a combined cytotoxic thyroglobulin and thyroperoxidase epitope-specific cellular immunity in Hashimoto's thyroiditis.

TPO TG

6.92e-06292222259066
Pubmed

RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.

RYR1 RYR3

6.92e-06292211500519
Pubmed

Increased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor.

LRP1 ADAM10

2.07e-05392230279425
Pubmed

Structural Basis of Formation of the Microtubule Minus-End-Regulating CAMSAP-Katanin Complex.

KATNB1 CAMSAP3

2.07e-05392229395789
Pubmed

Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.

RYR1 RYR3

2.07e-05392218403125
Pubmed

Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.

RYR1 RYR3

2.07e-05392211171121
Pubmed

Type I interferons modulate the expression of thyroid peroxidase, sodium/iodide symporter, and thyroglobulin genes in primary human thyrocyte cultures.

TPO TG

2.07e-05392215562032
Pubmed

Inverse Data-Driven Modeling and Multiomics Analysis Reveals Phgdh as a Metabolic Checkpoint of Macrophage Polarization and Proliferation.

TSC2 PHGDH

2.07e-05392232023468
Pubmed

Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.

RYR1 RYR3

2.07e-05392218313230
Pubmed

TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.

TPO TG

2.07e-05392234896620
Pubmed

Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.

RYR1 RYR3

2.07e-05392218434746
Pubmed

SPRY domains in ryanodine receptors (Ca(2+)-release channels).

RYR1 RYR3

2.07e-0539229204703
Pubmed

The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.

RYR1 RYR3

2.07e-0539227876312
Pubmed

Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.

RYR1 RYR3

2.07e-05392221881589
Pubmed

Transitional B cells commit to marginal zone B cell fate by Taok3-mediated surface expression of ADAM10.

TAOK3 ADAM10

2.07e-05392228068307
Pubmed

Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).

RYR1 RYR3

2.07e-05392212213830
Pubmed

Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.

RYR1 RYR3

2.07e-0539229242641
Pubmed

Genotypes and phenotypes of congenital goitre and hypothyroidism caused by mutations in dual oxidase 2 genes.

TPO TG

2.07e-05392224735383
Pubmed

Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.

RYR1 RYR3

2.07e-05392222948152
Pubmed

Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.

RYR1 RYR3

2.07e-05392210788707
Pubmed

Molecular cloning and initial characterization of three novel human sulfatases.

ARSJ ARSI

2.07e-05392216500042
Pubmed

Relationship of clinical features and laboratory parameters to thyroid echogenicity measured by standardized grey scale ultrasonography in patients with Hashimoto's thyroiditis.

TPO TG

2.07e-05392212709678
Pubmed

Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.

RYR1 RYR3

2.07e-05392225239916
Pubmed

Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.

RYR1 RYR3

2.07e-0539227621815
Pubmed

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.

RYR1 RYR3

2.07e-05392218643873
Pubmed

Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).

RYR1 RYR3

2.07e-05392211159936
Pubmed

Homology between TSH-R/Tg/TPO and Hashimoto's encephalopathy autoantigens.

TPO TG

2.07e-05392231585887
Pubmed

Elevated blood Hsp60, its structural similarities and cross-reactivity with thyroid molecules, and its presence on the plasma membrane of oncocytes point to the chaperonin as an immunopathogenic factor in Hashimoto's thyroiditis.

TPO TG

2.07e-05392224057177
Pubmed

Comprehensive Screening of Eight Known Causative Genes in Congenital Hypothyroidism With Gland-in-Situ.

TPO TG

2.07e-05392227525530
Pubmed

Molecular identification of the ryanodine receptor pore-forming segment.

RYR1 RYR3

2.07e-05392210473538
Pubmed

Biological variation of thyroid autoantibodies and thyroglobulin.

TPO TG

2.07e-05392217902201
Pubmed

Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.

RYR1 RYR3

2.07e-0539227959768
Pubmed

The organization of proteins in the human red blood cell membrane. A review.

RYR1 RYR3

2.07e-0539224600883
Pubmed

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

RYR1 RYR3

2.07e-0539227635066
Pubmed

The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.

KATNB1 FAM83D DGKH CCNA2 AGAP2 FANCA

3.23e-0522792626410627
Pubmed

Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.

RYR1 RYR3

4.14e-05492222100703
Pubmed

A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.

RYR1 RYR3

4.14e-05492218206662
Pubmed

A hereditary model of slowly progressive polycystic kidney disease in the mouse.

NPHP3 MYO5A

4.14e-0549221883968
Pubmed

IKKbeta suppression of TSC1 function links the mTOR pathway with insulin resistance.

TSC2 IKBKB

4.14e-05492218949383
Pubmed

Ryanodine receptor calcium release channels: lessons from structure-function studies.

RYR1 RYR3

4.14e-05492223413940
Pubmed

Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.

RYR1 RYR3

4.14e-0549229384575
Pubmed

Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.

RYR1 RYR3

4.14e-0549229607712
Pubmed

An autophagy-related model of 4 key genes for predicting prognosis of patients with laryngeal cancer.

TSC2 IKBKB

4.14e-05492232791689
Pubmed

Linkage analysis of two murine polycystic kidney disease genes, pcy and cpk.

NPHP3 MYO5A

4.14e-0549221748176
Pubmed

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.

RYR1 RYR3

4.14e-05492223482488
Pubmed

Genetic mapping of the polycystic kidney gene, pcy, on mouse chromosome 9.

NPHP3 MYO5A

4.14e-0549228825940
Pubmed

Docking motif-guided mapping of the interactome of protein phosphatase-1.

PPP1R26 CAMSAP3 TSC2 CSMD1

6.22e-058092419389623
Pubmed

Hamartin and tuberin interaction with the G2/M cyclin-dependent kinase CDK1 and its regulatory cyclins A and B.

TSC2 CCNA2

6.89e-05592211444800
Pubmed

Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction.

FAN1 FANCA

6.89e-05592226980189
Pubmed

Follicular cells of the thyroid gland require Pax8 gene function.

TPO TG

6.89e-0559229590297
Pubmed

TAO-kinase 3 governs the terminal differentiation of NOTCH2-dependent splenic conventional dendritic cells.

TAOK3 ADAM10

6.89e-05592233214146
Pubmed

Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.

RYR1 RYR3

6.89e-05592223918386
Pubmed

Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition.

KATNB1 CAMSAP3

6.89e-05592224486153
Pubmed

Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.

RYR1 RYR3

6.89e-05592219011160
Pubmed

Fanconi anemia protein complex is a novel target of the IKK signalsome.

IKBKB FANCA

6.89e-05592212210728
Pubmed

Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.

RYR1 RYR3

1.03e-04692219549818
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR1 RYR3

1.03e-04692226025922
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR3

1.03e-04692223463619
Pubmed

Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.

RYR1 RYR3

1.03e-04692210444070
Pubmed

Tuberin binds p27 and negatively regulates its interaction with the SCF component Skp2.

TSC2 CCNA2

1.03e-04692215355997
Pubmed

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

RYR1 RYR3

1.03e-04692214592808
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR3

1.03e-04692220519450
Pubmed

A mouse model demonstrates a multigenic origin of congenital hypothyroidism.

TPO TG

1.03e-04692216150900
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR3

1.03e-04692225966694
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR1 RYR3

1.03e-04692219009018
Pubmed

15q13.3 Recurrent Deletion

TRPM1 FAN1

1.03e-04692221290787
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR3

1.03e-04692216844763
Pubmed

Molecular characteristics in papillary thyroid cancers (PTCs) with no 131I uptake.

TPO TG

1.03e-04692217854396
Pubmed

Secreted heat shock protein 90α (HSP90α) induces nuclear factor-κB-mediated TCF12 protein expression to down-regulate E-cadherin and to enhance colorectal cancer cell migration and invasion.

LRP1 IKBKB

1.03e-04692223386606
Pubmed

FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.

KLF9 FGFR2 RYR1

1.41e-043892326134413
Pubmed

Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship.

ARSJ ARSI

1.44e-04792216174644
Pubmed

Role of myosin VIIa and Rab27a in the motility and localization of RPE melanosomes.

MYO5A PCDH15

1.44e-04792215572405
Pubmed

ADAM binding protein Eve-1 is required for ectodomain shedding of epidermal growth factor receptor ligands.

SH3D19 ADAM10

1.44e-04792215280379
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR3

1.44e-04792211860456
Pubmed

NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK.

NLRX1 IKBKB

1.44e-04792221703539
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR1 RYR3

1.44e-04792220962236
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NAA25 FBH1 MYO5A SH3D19 POLR1C DEF8 LRP1 TSC2 PC RYR3 AGAP2 FAN1

1.46e-041285921235914814
Pubmed

Myogenic-specific ablation of Fgfr1 impairs FGF2-mediated proliferation of satellite cells at the myofiber niche but does not abolish the capacity for muscle regeneration.

FGFR2 ITGA7

1.92e-04892226074812
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R26 CAMSAP3 TSC2 CSMD1 RYR1 PPP1R1A

2.96e-05181606694
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR3

3.24e-053602287
GeneFamilyShisa family members

SHISA9 SHISA3

2.99e-048602742
GeneFamilyDNA helicases

FBH1 RTEL1

1.43e-03176021167
GeneFamilySulfatases

ARSJ ARSI

1.60e-0318602410
GeneFamilyCD molecules|Integrin alpha subunits

ITGA11 ITGA7

1.60e-03186021160
GeneFamilyMitochondrial ribosomal proteins

MRPL27 MRPL28 MRPL9

2.30e-0379603646
GeneFamilyTransient receptor potential cation channels

TRPM5 TRPM1

3.87e-0328602249
CoexpressionGSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_UP

ARSJ CCDC78 SPG11 FLRT1 PTGDR FAN1

1.20e-05144926M9003
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2C

DNAAF3 TAOK3 SH3D19 LRP1 CSMD1 CENPK PHGDH SHISA3

1.93e-05325928M39053
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_LARGE_PRE_B_CELL

REC8 ASNSD1 TOR2A MTHFD2 KATNB1 MRPL27 RBM15B FAM83D CEP131 AP4M1 DCTPP1 CENPK MRPL9 PHGDH CCNA2 FANCA

1.96e-0513639216M45782
CoexpressionPARENT_MTOR_SIGNALING_UP

GALT CATSPER2 RTEL1 TMC6 LRP1 TSC2 DGKH FLRT1 ITGA7 PHGDH

3.05e-055679210M16909
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

TCAF2 UTS2 ZC3H12D AKNA DGKH IKBKB

6.46e-0714892680470353e12599440f711b6e107730763376d04d
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

UBXN11 FAM83D ZBTB18 CCNA2 BORA FANCA

1.50e-061719266e7ade1d14a3ec4c566476aac3eb509bd2661e39
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

SGCZ PCDH15 CSMD1 PTGDR RYR1 RYR3

1.50e-06171926b2e753e811a7639956994609f73efcdb62d04f82
ToppCellE12.5-Mesenchymal-developing_mesenchymal_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MTHFD2 FAM83D DCTPP1 CENPK CCNA2 BORA

3.21e-0619592697b2ff072cc830a4a2cb217f5a215ca6cad505ec
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC8 SGCZ CAMSAP3 DEF8 RAPGEFL1

9.67e-06137925e9b88ad86b75454a8292a94879c5b665adc42744
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGCZ PCDH15 TRPM1 CSMD1 RYR1

2.51e-051679253edb0570e583bb527165bcd8a4c25a042054043b
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PPP1R26 DHRS13 DCTPP1 CENPK CCNA2

2.90e-051729257c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TPO TCAF2 ITGA11 ARSJ RYR3

3.06e-0517492543c0e758fa8683708475aec846929ac70d41d7f5
ToppCellMS-Treg-naive_CD4|MS / Condition, Cell_class and T cell subcluster

UTS2 DGKH PRR14L CENPK CCNA2

3.60e-051809257ca083616926d98420fa11a6e5ebc981623f79ac
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TPO ADAMTS19 ITGA11 ARSJ RYR3

3.60e-05180925e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

KANSL1 ZC3H12D DGKH ANKRD12 IKBKB

3.69e-05181925f2315414e714ac86211546a935660c4be6e85f1b
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TPO ADAMTS19 ITGA11 ARSJ RYR3

3.79e-0518292572e65a23cd36085bc880087d3cae92395de918a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TPO ADAMTS19 ITGA11 ARSJ RYR3

3.79e-0518292505c167158815bf25d509df59ab386e1990712765
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAM83D CENPK CCNA2 BORA FANCA

4.10e-0518592530e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-hematologic-hematopoietic_progenitor-common_myeloid_progenitor|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DNAAF3 FAM83D PGAP4 DCTPP1 RYR3

4.10e-05185925eac18ddcdac60b829619f7657e833d08cc9bcbab
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

REC8 SHISA9 TCAF2 NUMBL FLRT1

4.65e-051909253cf464664d6aa22b212e60b70885953887e92483
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM83D CENPK PHGDH CCNA2 FANCA

4.77e-0519192550854384fdaa0efa2e3227659d544ed09ac102f2
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FAM83D DCTPP1 CENPK PHGDH CCNA2

4.77e-05191925b978afe76754cc56e1672abca27be289bb56375b
ToppCellNon-neuronal-Dividing-Radial_Glia-Low_Quality-16|World / Primary Cells by Cluster

FAM83D CENPK PHGDH CCNA2 BORA

4.89e-051929250d6413df15dfecdffc777fb02df3aaf0c30540b1
ToppCellNon-neuronal-Dividing-Radial_Glia-Low_Quality|World / Primary Cells by Cluster

FAM83D CENPK PHGDH CCNA2 BORA

4.89e-051929255fa5b2f250ec5ad5a232c022266f0cd01ff4a753
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SGCZ ITGA11 MTHFD2 CENPK FANCA

5.01e-05193925516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ TRPM5 MTHFD2 PC PPP1R1A

5.26e-0519592558b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF9 PCDH15 LRP1 CSMD1 RYR3

5.39e-051969256bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF9 PCDH15 LRP1 CSMD1 RYR3

5.39e-05196925c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.39e-051969255905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ARSJ FAM83D CENPK CCNA2 SHISA3

5.66e-051989251fa213e79d828bff6465bde116536dd1b80d94e0
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CEP131 CENPK CCNA2 BORA

5.66e-05198925629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCellParenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

RPAP1 FAM83D ITGA7 ARMC2 PPP1R1A

5.66e-05198925cc2b5b632e73e44bb60050f0db10d8f0dbb859fa
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.66e-05198925dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCellNon-neuronal-Dividing-IPC-IPC-div1-28|World / Primary Cells by Cluster

FAM83D CENPK PHGDH CCNA2 BORA

5.79e-05199925787688b68ae5d8768c0a24673ae07ab07616764a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-OPC_related-OPC|GW12 / Sample Type, Dataset, Time_group, and Cell type.

RTEL1 ESYT1 SH3D19 PCDH15 SHISA3

5.79e-05199925c0dc14fb9899d4263264347436de121814441dfb
ToppCellNon-neuronal-Dividing-IPC-IPC-div1|World / Primary Cells by Cluster

FAM83D CENPK PHGDH CCNA2 BORA

5.79e-0519992572823f26ecabcae1b514b7629cfce010c97b929a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.79e-05199925ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FAM83D FGFR2 CENPK CCNA2 RAPGEFL1

5.79e-05199925fe22833e69928a1478df265e1c356c463611dedd
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.79e-05199925d8f904f531bfe091b7d8caaa147ea4a03d627995
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-OPC_related|GW12 / Sample Type, Dataset, Time_group, and Cell type.

RTEL1 ESYT1 SH3D19 PCDH15 SHISA3

5.79e-051999259bc53ff93ca97af4ee0f01c74a567987a26abb18
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FAM83D CENPK ARSI CCNA2 SHISA3

5.93e-05200925dd5b753bb1333fa502b9d3a6d65a53a9882b2451
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating|1_mon / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.93e-05200925762442d125e594fede4506b72da15563b1d8798a
ToppCellsevere-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DCTPP1 CENPK PHGDH CCNA2 FANCA

5.93e-05200925d341f4e500377a5bef82c24bf64704b981053336
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 FGFR2 ARSI TPBG SHISA3

5.93e-052009253dacd0afe69bc16bb33336ea9ea99a9cd47731d9
ToppCellNon-neuronal-Dividing-IPC|World / Primary Cells by Cluster

FAM83D CENPK PHGDH CCNA2 BORA

5.93e-05200925971533181daa1bfac1f1b8c507d2013f891f9078
ToppCellNon-neuronal-Dividing-Radial_Glia-vRG-17|World / Primary Cells by Cluster

FAM83D CENPK PHGDH CCNA2 BORA

5.93e-052009254417f14d45ce683c1a45ec989ae63ee6c047353e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.93e-052009250bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 FGFR2 ARSI TPBG SHISA3

5.93e-05200925ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors_nGenesUnder4k|1_mon / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.93e-05200925243c7f88befd402a57e9226706811c802b28e3fd
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

FAM83D CENPK PHGDH CCNA2 BORA

5.93e-05200925c9479452ab8c51139522383f745f02171ebbd7e2
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Ptgfr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAVER2 RYR1 RYR3 TPBG

1.40e-04127924fb58f4b4d3722f4b9a2e4946c0244c5b70dd883b
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_smooth_muscle-like|E16.5-samps / Age Group, Lineage, Cell class and subclass

TPO RAVER2 PCDH15 PPP1R1A

1.62e-041329249633653dba1edee47d915212fb6e68426da49de5
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_PT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SGCZ RAVER2 RYR1 RYR3

1.72e-04134924cb676d5bbc468bd3ce1b6712d41c986ee9221ac5
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2|E16.5-samps / Age Group, Lineage, Cell class and subclass

SHISA9 NKX2-8 RIOX1 RYR3

1.92e-0413892405de2cef97c0912fb23f138dd45348f565a14d74
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CAMSAP3 LRP1 FGFR2 TG

2.14e-04142924d52da766e031f7409eb5a7a9fa88f48e14a79d8b
ToppCellLPS-IL1RA+antiTNF-Endothelial-Epi-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CAMSAP3 LRP1 FGFR2 TG

2.14e-04142924a05b320cf182b2aaf18df7c40045dc65b659bf20
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

UBXN11 RAVER2 ZBTB18 RYR1

2.20e-041439245fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IL17B CSMD1 ITGA7 METTL17

2.38e-041469242ac9b487a7991fdc15444aeb93533030e09825bb
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

RAVER2 ZBTB18 RYR3 AGAP2

2.44e-041479248f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

NKX2-8 KANSL1 AKNA DGKH

2.44e-0414792494998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRX1 LRP1 DGKH RYR1

2.78e-0415292482a493ffb2f1704cd6f68a82d970fe12f537d20e
ToppCellPBMC-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

NPHP3 FAM83D RIOX1 RAPGEFL1

2.85e-04153924db1a6914f2033fb0748e0523cffe5d6dc4e901be
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UBXN11 DHRS13 RIOX1 CCNA2

2.85e-04153924991782d111d66e25b40319d4e6dea40f2c2c0805
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGCZ KATNB1 PTGDR RAPGEFL1

2.99e-0415592451f6447945389649d99dcf7603b396195c631ead
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGCZ KATNB1 PTGDR RAPGEFL1

2.99e-0415592423dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

KANSL1 ZC3H12D DGKH ANKRD12

3.07e-041569241545169694f686d28648a68b552c2ae606599d66
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGCZ KATNB1 CAMSAP3 RBM15B

3.14e-04157924bd45590da540a557dc8096980a45220fccb99505
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SGCZ KATNB1 CAMSAP3 RBM15B

3.14e-0415792400c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POLR1C PCDH15 CCNA2 FAN1

3.22e-041589247f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellBac-SEP-Lymphocyte-T_NK-NK_CD56bright|Bac-SEP / Disease, Lineage and Cell Type

RPAP1 CCDC78 PTGDR MRPL9

3.22e-0415892420411158d71699a80f6c1566791af89dea0e1875
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

SGCZ PCDH15 CSMD1 RYR1

3.29e-041599245335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellCOVID-CD4-CD4_Treg|COVID / Condition, Cell_class and T cell subcluster

RAVER2 SPG11 TPBG FANCA

3.29e-04159924037cd97c41eb2f91fd3f69bbb3ffdfd6c0158410
ToppCell10x5'-Lung-Lymphocytic_NK-NK_CD56bright_CD16-|Lung / Manually curated celltypes from each tissue

CCDC78 AKNA DHRS13 PPP1R1A

3.29e-04159924595643e9433265308e5aab7f906229025701cf6a
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PPP1R26 UBXN11 CEP131 ARSI

3.45e-041619249703b7e67d9fadb6129cad166bd01be915042e44
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

TAOK3 PCDH15 PC RYR1

3.45e-04161924347edb0de10850b7d16c40945751033289289c9b
ToppCelldroplet-Heart-nan-18m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPK RYR1 CCNA2 FANCA

3.54e-041629247f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCellfacs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS19 ITGA11 AP4M1 PTGDR

3.54e-0416292456f1789e69a6cb29956e46aba92b290847327c1f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CATSPER2 ESYT1 POLR1C CEP131

3.62e-041639241c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

REC8 SGCZ MYO5A DEF8

3.62e-04163924132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF3 MTHFD2 LRP1 RAPGEFL1

3.70e-04164924cd0794f84dfd346807e2d803723718b7f22e9232
ToppCelldroplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF3 MTHFD2 LRP1 RAPGEFL1

3.70e-0416492412251a49fd4af32d4edb58046245548c260cf04b
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|356C / Donor, Lineage, Cell class and subclass (all cells)

PPP1R26 FKBP6 CATSPER2 TG

3.79e-0416592435a6de30438de364ccca948fc932da541a69ef89
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPHP3 UBXN11 KATNB1 IKBKB

3.79e-041659248c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12D PHGDH RYR1 TG

3.79e-0416592436415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12D PHGDH RYR1 TG

3.79e-0416592456310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCelldroplet-Fat-SCAT-30m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12D PHGDH FAN1 TG

3.88e-041669244b31d2755108b2815316411a38bfb11fd30ef98a
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

TOR2A RAVER2 CSMD1 PHGDH

3.88e-0416692420f248d95c86eb52a1efe9abe73123fbe4206caf
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Bdnf_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CCDC78 ZC3H12D FANCA

3.93e-046992324a480394630385ee51b1dfe1123480107a11403
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Bdnf_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CCDC78 ZC3H12D FANCA

3.93e-04699231ab1d92e03a31bb1fe87f055d407a81c4d1d81b8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TPO PCDH15 ITGA7

3.93e-04699231592edde44c3927d6a2350eb00f92c10d3adf692
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PPP1R26 FKBP6 CATSPER2 TG

3.97e-041679247e61c5d2cdcfa6a2e3484b3994aec6b64ad75f07
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12D CENPK PHGDH AGAP2

3.97e-041679244520ee71e2b119c1dfa0e342fe57eda5f3598650
ToppCell368C-Myeloid-Dendritic-pDC|368C / Donor, Lineage, Cell class and subclass (all cells)

NAA25 RPAP1 AGAP2 BORA

3.97e-041679241e2fc1637769405a61f4c7e44945712a1888a299
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c03-MKI67|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAVER2 DHRS13 CEP131 CCNA2

3.97e-041679249280558baddea51aae47f3383d895a9b0c6749a4
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO5A PHGDH TPBG TG

4.06e-04168924ce9fae8b295c668b0959d5007a8bcd401d80e258
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTEL1 AKNA FAM83D IKBKB

4.06e-04168924182f08106ac65ea501e2fb9139d3b44b7c4662c9
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_SLITRK6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SGCZ ARSJ PCDH15 RYR3

4.15e-041699241c9e54e7b14eb99996590fb93b257cf881a9f184
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAM83D CENPK CCNA2 FANCA

4.15e-04169924b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANSL1 ADAM10 ZBTB18 FANCA

4.15e-041699244e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BCLAF3 RPAP1 CATSPER2 SPG11

4.15e-04169924665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCAF2 TBC1D30 DGKH SHISA3

4.15e-0416992487116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DGKH CENPK CCNA2 BORA

4.15e-041699242833a8a7094e4d407eb923f2bc59b9b112c6bae4
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BCLAF3 RPAP1 CATSPER2 SPG11

4.15e-041699246614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellBasal_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DGKH TPBG RAPGEFL1 TG

4.24e-04170924776d4224a682b6c648041827efd69794f88906f0
Drugperchlorate

TPO AP4M1 PC RYR1 RYR3 TG

1.75e-0690926CID000024247
Drug5'-adenylyl (beta,gamma-methylene)diphosphonate

RYR1 RYR3

1.62e-052922ctd:C005147
DrugCefotetan [69712-56-7]; Down 200; 7uM; HL60; HT_HG-U133A

RPAP1 KLF9 NLRX1 TMC6 KATNB1 AP4M1 FANCA

1.64e-051999271319_DN
Drugbimoclomol

IKBKB RYR1 RYR3

2.25e-0514923CID009576891
Drug2-hydroxycarbazole

RYR1 RYR3

4.83e-053922CID000093551
Drug1,1'-diheptyl-4,4'-bipyridinium

RYR1 RYR3

4.83e-053922CID000080262
Drugcis-diammineplatinum(II

RYR1 RYR3

4.83e-053922CID000159790
Drug2-hydroxyheptanoic acid

RYR1 RYR3

4.83e-053922CID002750949
Drugflubendiamide

RYR1 RYR3

4.83e-053922CID011193251
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR1 RYR3

4.83e-053922CID005748312
Drug8N3-cADPR

RYR1 RYR3

4.83e-053922CID000127713
Drugaminodantrolene

RYR1 RYR3

4.83e-053922CID009570289
DiseaseCongenital Fiber Type Disproportion

CCDC78 ITGA7 RYR1

2.17e-0518903C0546264
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR3

2.75e-053902DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR3

2.75e-053902DOID:8545 (implicated_via_orthology)
Diseasediet measurement, bilirubin measurement

SH3D19 IL17B RAVER2

6.78e-0526903EFO_0004570, EFO_0008111
DiseaseThyroid Dyshormonogenesis 1

TPO TG

1.37e-046902C1848805
Diseasephosphate measurement

MTHFD2 RYR3

1.91e-047902EFO_0010968
DiseaseGoiter

TPO TG

1.91e-047902C0018021
DiseaseCiliopathies

DNAAF3 NPHP3 PCDH15 TSC2

3.65e-04110904C4277690
DiseaseCongenital muscular dystrophy

ITGA7 RYR1

5.95e-0412902cv:C0699743
DiseaseAutosomal Dominant Myotubular Myopathy

CCDC78 RYR1

7.02e-0413902C3661489
Diseasecardiomyopathy (biomarker_via_orthology)

UTS2 ADAM10

7.02e-0413902DOID:0050700 (biomarker_via_orthology)
DiseaseCentronuclear myopathy

CCDC78 RYR1

7.02e-0413902C0175709
DiseaseX-linked centronuclear myopathy

CCDC78 RYR1

7.02e-0413902C0410203
Diseasemale infertility (implicated_via_orthology)

FKBP6 ARMC2

7.02e-0413902DOID:12336 (implicated_via_orthology)
DiseaseMyopathy, Centronuclear, 1

CCDC78 RYR1

7.02e-0413902C4551952
DiseaseCongenital Hypothyroidism

TPO TG

7.02e-0413902C0010308
DiseaseCongenital Structural Myopathy

CCDC78 RYR1

7.02e-0413902C0752282
DiseaseAlzheimer's disease (biomarker_via_orthology)

LRP1 IKBKB ADAM10

7.50e-0458903DOID:10652 (biomarker_via_orthology)
DiseaseMyopathy, Centronuclear, Autosomal Dominant

CCDC78 RYR1

8.17e-0414902C1834558
DiseaseTubular Aggregate Myopathy

CCDC78 RYR1

8.17e-0414902C0410207
Diseasecentral nervous system cancer, glioblastoma multiforme

RTEL1 RAVER2

8.17e-0414902EFO_0000326, EFO_0000519
Diseasecongenital hypothyroidism (implicated_via_orthology)

TPO TG

8.17e-0414902DOID:0050328 (implicated_via_orthology)
DiseaseProfound Mental Retardation

KANSL1 FGFR2 AP4M1 CCNA2

8.81e-04139904C0020796
DiseaseMental Retardation, Psychosocial

KANSL1 FGFR2 AP4M1 CCNA2

8.81e-04139904C0025363
DiseaseMental deficiency

KANSL1 FGFR2 AP4M1 CCNA2

8.81e-04139904C0917816
DiseaseAnilide use measurement

KANSL1 LRP1

9.41e-0415902EFO_0009938
DiseaseAutosomal Recessive Centronuclear Myopathy

CCDC78 RYR1

9.41e-0415902C3645536
Diseasemagnesium measurement

ADAMTS19 SGCZ FGFR2

1.09e-0366903EFO_0004845
Diseasejoint damage measurement

SGCZ CSMD1 TG

1.19e-0368903EFO_0005413
Diseasecardiomyopathy (implicated_via_orthology)

SGCZ LRP1 ITGA7

1.35e-0371903DOID:0050700 (implicated_via_orthology)
Diseaseobsessive-compulsive disorder, autism spectrum disorder

SGCZ DEF8

1.52e-0319902EFO_0003756, EFO_0004242
Diseasebehavioural disinhibition measurement

ARSJ CSMD1 SHISA3

1.58e-0375903EFO_0006946
Diseasenicotine dependence symptom count, depressive symptom measurement

ITGA11 PCDH15 PHGDH

1.58e-0375903EFO_0007006, EFO_0009262
Diseasememory performance

DNAAF3 SGCZ TBC1D30 CSMD1 ARMC2 PHGDH

1.60e-03409906EFO_0004874
Diseaseacetate measurement

CATSPER2 SPG11

1.69e-0320902EFO_0010112
Diseasepulmonary hypertension (biomarker_via_orthology)

UTS2 RYR1 RYR3

1.90e-0380903DOID:6432 (biomarker_via_orthology)
Diseaseglioma

RTEL1 RAVER2

2.04e-0322902EFO_0005543
Diseasesensory peripheral neuropathy, remission

SGCZ CSMD1

2.23e-0323902EFO_0009785, MONDO_0002321
Diseaseairway responsiveness measurement

PCDH15 CSMD1

2.43e-0324902EFO_0006897
Diseaseresponse to radiation

NUMBL CSMD1 TPBG

2.50e-0388903GO_0009314
DiseaseTEMPS-A questionnaire

SGCZ CSMD1

2.64e-0325902EFO_0004783

Protein segments in the cluster

PeptideGeneStartEntry
APELRQRLTHVDSPL

ESYT1

951

Q9BSJ8
REENEILPPDHLNGV

SDF4

51

Q9BRK5
SQAVPRHTIRELLDP

CATSPER2

36

Q96P56
RQPETPAHADVRAID

CSMD1

3276

Q96PZ7
IPQEEHAANGPELLR

ADAM10

196

O14672
RASPRTEILHNIDPL

ARSI

381

Q5FYB1
HRAQRPPSEAEDVLI

ARMC2

591

Q8NEN0
VEDPQLRSPLHLAAE

AGAP2

1086

Q99490
IRLTEDDDPQIHHPR

ANKRD12

1771

Q6UB98
ALPERPVREADLRHQ

CAMSAP3

116

Q9P1Y5
LDEFESHRILRLQPP

AP4M1

261

O00189
TAAAIPRRHAPLEQL

NUMBL

286

Q9Y6R0
PAALHPEEVAARLQR

RAVER2

46

Q9HCJ3
RNLDADLVRDRTPPH

RBM15B

521

Q8NDT2
DIPQIRHLLEAAIPE

REC8

151

O95072
REASPQPLEELDHLL

PTGDR

251

Q13258
QHAEPDGDEVLLRIP

ADAMTS19

156

Q8TE59
EHGVAPDAERLRLPE

KLF9

26

Q13886
LDVVERSPHRPILQA

FGFR2

246

P21802
NHDPSRIPVDLPEAR

IL17B

106

Q9UHF5
RRLTHPNVVAARDVP

IKBKB

66

O14920
IEHPRAIALDPRDGI

LRP1

1386

Q07954
LRSPRVDILHNIDPI

ARSJ

411

Q5FYB0
QQRPPVDEVLREGHI

KIAA1109

871

Q2LD37
VARDPVQDHRPLAQP

KATNB1

311

Q9BVA0
ENRVALHALTRPPAL

NAT14

31

Q8WUY8
VRRLDASFQEHPDLP

TPO

501

P07202
NPDEVHAILRAAERP

FAM83D

61

Q9H4H8
EELTRADPEQRHVPL

KANSL1

416

Q7Z3B3
TPVEEDLRRAPQLNH

ITGA11

1046

Q9UKX5
PEEQIFPVLEHLLRA

PGAP4

216

Q9BRR3
DELLRPPAELALEHQ

NLRX1

121

Q86UT6
DLPEQDAQHLPRREP

NKX2-8

16

O15522
VGRVPLQLESPHEER

DGKH

1066

Q86XP1
LRRRSAPPEEQHLVE

FKBP6

201

O75344
HPRTAELSLLEPVNR

PCDH15

341

Q96QU1
RDHPLLPEAEACVRQ

FBH1

316

Q8NFZ0
EIPLNSDPEIHRRID

BCLAF3

511

A2AJT9
RAQADLLAHLVPEPD

DNAAF3

131

Q8N9W5
LLAHLVPEPDRLEEQ

DNAAF3

136

Q8N9W5
PEQAAERLRALPEVH

GALT

351

P07902
INTPRLEPREHMAVD

FANCA

706

O15360
INPVEIDPEDIHRQA

BORA

66

Q6PGQ7
LEILINRLFDVPHDP

CENPK

216

Q9BS16
VEDRPQDPLARLRHK

AKNA

736

Q7Z591
ESDPRHPRAAAQELR

CCDC78

116

A2IDD5
RHIPLDEPIDLLNVA

ASNSD1

341

Q9NWL6
DPNEDEPNIRVLLEH

DEF8

186

Q6ZN54
PRPNILHLDVDSRDR

ITGA7

941

Q13683
SPEPTLEDIRRLHAE

DCTPP1

26

Q9H773
DEFPINLPRSLRELH

FLRT1

91

Q9NZU1
RVAPLKDLPVNDEHV

CCNA2

71

P20248
HEAVLPRERLHLEPI

RYR1

811

P21817
DHLEELLEQHRRPTP

CEP131

1066

Q9UPN4
SRHLPVEPEELQRRA

METTL17

96

Q9H7H0
HVEEVPPAARDDRAA

DHRS13

286

Q6UX07
HPPLEGRADVIADIQ

PRR14L

691

Q5THK1
PALEARLQLIHDAPE

FAN1

881

Q9Y2M0
EHSIPRRQRAQPVLD

RTEL1

981

Q9NZ71
PHEDARLTPEELERA

UTS2

36

O95399
IITPLDEHLRSRPND

SH3D19

471

Q5HYK7
AQAHEALSPPERERR

TCAF2

796

A6NFQ2
PEHIDERRICNAVSP

MTHFD2

136

P13995
EIRETALDPDHPRVA

NPHP3

971

Q7Z494
DRRELEHPGITAQPV

SHISA3

81

A0PJX4
NLPLHPVRVEDEPRA

SHISA9

321

B4DS77
IPQERPTSAELLRHD

TAOK3

261

Q9H2K8
RVQLREERAPDPPAH

PPP1R26

391

Q5T8A7
ETPHIRAEPSQDLRL

SGCZ

181

Q96LD1
RPVHDDILIAQLRPG

POLR1C

191

O15160
IHDSLPPVLTDRERA

RIOX1

506

Q9H6W3
VQELLRPRHEGNAPD

MRPL9

26

Q9BYD2
LEEEAPDIPLRRVHS

SPG11

1941

Q96JI7
ELEPVISRAVLDNPH

TOR2A

226

Q5JU69
REHLERDLPDPLDQK

TRPM5

1036

Q9NZQ8
LPPHLEKIRDRLAEN

RYR3

861

Q15413
PAHLAPLREDSVLRE

ZBTB18

311

Q99592
RQDPQLHPEDPERRA

MRPL28

171

Q13084
QRDAAAETELRVHPP

TBC1D30

826

Q9Y2I9
DRPPLQDHRDVVMLD

RPAP1

46

Q9BWH6
PRADTPIREQHVLAE

ZC3H12D

141

A2A288
QDEHHVAEAIPRIPR

TRPM1

1506

Q7Z4N2
PPRDRALVDHENVIS

PHGDH

266

O43175
PRDVLAQLPSLRHLD

TPBG

226

Q13641
RVLAALEPHDSPVLE

TMC6

491

Q7Z403
PHPRNTEAVDLITRL

MRPL27

106

Q9P0M9
GAPERPEHLLNRVLE

RAPGEFL1

146

Q9UHV5
PVASLPDLHDIERAL

TG

1376

P01266
LLEPHLDPEAAEQIR

PPP1R1A

16

Q13522
EIAPAAHLDPQLRTR

PC

276

P11498
ADLLQPERPLEARHA

TSC2

86

P49815
ALEDLVQTLRPHPAE

UBXN11

106

Q5T124
LPPEARIEASLQHEI

MYO5A

1391

Q9Y4I1
HVQDPNDRRLRPIYD

NAA25

6

Q14CX7