| Category | Name | IntersectionWithQuery | PValue | GenesInTerm | GenesInQuery | GenesInTermInQuery | ID |
|---|---|---|---|---|---|---|---|
| GeneOntologyMolecularFunction | structural constituent of presynaptic active zone | 1.20e-04 | 8 | 42 | 2 | GO:0098882 | |
| GeneOntologyMolecularFunction | histone binding | 2.26e-04 | 265 | 42 | 5 | GO:0042393 | |
| GeneOntologyBiologicalProcess | presynapse to nucleus signaling pathway | 1.21e-05 | 3 | 42 | 2 | GO:0099526 | |
| GeneOntologyBiologicalProcess | presynaptic signal transduction | 2.42e-05 | 4 | 42 | 2 | GO:0098928 | |
| GeneOntologyBiologicalProcess | presynaptic active zone assembly | 4.03e-05 | 5 | 42 | 2 | GO:1904071 | |
| GeneOntologyBiologicalProcess | maintenance of presynaptic active zone structure | 6.04e-05 | 6 | 42 | 2 | GO:0048790 | |
| GeneOntologyBiologicalProcess | maintenance of synapse structure | 7.36e-05 | 40 | 42 | 3 | GO:0099558 | |
| GeneOntologyBiologicalProcess | presynaptic active zone organization | 1.80e-04 | 10 | 42 | 2 | GO:1990709 | |
| GeneOntologyBiologicalProcess | regulation of mRNA export from nucleus | 2.20e-04 | 11 | 42 | 2 | GO:0010793 | |
| GeneOntologyBiologicalProcess | regulation of ribonucleoprotein complex localization | 3.11e-04 | 13 | 42 | 2 | GO:2000197 | |
| GeneOntologyBiologicalProcess | cell junction maintenance | 3.14e-04 | 65 | 42 | 3 | GO:0034331 | |
| GeneOntologyBiologicalProcess | modulation of chemical synaptic transmission | 3.48e-04 | 663 | 42 | 7 | GO:0050804 | |
| GeneOntologyBiologicalProcess | regulation of trans-synaptic signaling | 3.51e-04 | 664 | 42 | 7 | GO:0099177 | |
| GeneOntologyBiologicalProcess | ribonucleoprotein complex localization | 3.63e-04 | 14 | 42 | 2 | GO:0071166 | |
| GeneOntologyCellularComponent | cell cortex region | 1.24e-04 | 45 | 45 | 3 | GO:0099738 | |
| GeneOntologyCellularComponent | cytoskeleton of presynaptic active zone | 1.26e-04 | 8 | 45 | 2 | GO:0048788 | |
| GeneOntologyCellularComponent | presynaptic cytoskeleton | 4.06e-04 | 14 | 45 | 2 | GO:0099569 | |
| GeneOntologyCellularComponent | histone deacetylase complex | 8.14e-04 | 85 | 45 | 3 | GO:0000118 | |
| GeneOntologyCellularComponent | presynaptic active zone cytoplasmic component | 1.11e-03 | 23 | 45 | 2 | GO:0098831 | |
| GeneOntologyCellularComponent | cell cortex | 1.17e-03 | 371 | 45 | 5 | GO:0005938 | |
| GeneOntologyCellularComponent | inhibitory synapse | 2.03e-03 | 31 | 45 | 2 | GO:0060077 | |
| GeneOntologyCellularComponent | ribbon synapse | 2.16e-03 | 32 | 45 | 2 | GO:0097470 | |
| GeneOntologyCellularComponent | dendrite | 2.23e-03 | 858 | 45 | 7 | GO:0030425 | |
| GeneOntologyCellularComponent | dendritic tree | 2.25e-03 | 860 | 45 | 7 | GO:0097447 | |
| Domain | Znf_piccolo | 4.94e-06 | 2 | 42 | 2 | IPR008899 | |
| Domain | zf-piccolo | 4.94e-06 | 2 | 42 | 2 | PF05715 | |
| Domain | DUF1220 | 1.76e-04 | 9 | 42 | 2 | SM01148 | |
| Domain | NBPF | 2.68e-04 | 11 | 42 | 2 | PS51316 | |
| Domain | DUF1220 | 2.68e-04 | 11 | 42 | 2 | PF06758 | |
| Domain | NBPF_dom | 2.68e-04 | 11 | 42 | 2 | IPR010630 | |
| Domain | Znf_FYVE_PHD | 3.27e-04 | 147 | 42 | 4 | IPR011011 | |
| Domain | UBA-like | 4.00e-04 | 64 | 42 | 3 | IPR009060 | |
| Domain | - | 3.21e-03 | 449 | 42 | 5 | 3.30.40.10 | |
| Domain | Znf_RING/FYVE/PHD | 3.53e-03 | 459 | 42 | 5 | IPR013083 | |
| Domain | UBA | 4.40e-03 | 44 | 42 | 2 | IPR015940 | |
| Domain | FERM_M | 4.80e-03 | 46 | 42 | 2 | PF00373 | |
| Domain | UBA | 5.01e-03 | 47 | 42 | 2 | PS50030 | |
| Domain | FERM_central | 5.43e-03 | 49 | 42 | 2 | IPR019748 | |
| Domain | FERM_domain | 5.43e-03 | 49 | 42 | 2 | IPR000299 | |
| Domain | FERM_1 | 5.65e-03 | 50 | 42 | 2 | PS00660 | |
| Domain | FERM_2 | 5.65e-03 | 50 | 42 | 2 | PS00661 | |
| Domain | Band_41_domain | 5.65e-03 | 50 | 42 | 2 | IPR019749 | |
| Domain | B41 | 5.65e-03 | 50 | 42 | 2 | SM00295 | |
| Domain | FERM/acyl-CoA-bd_prot_3-hlx | 5.65e-03 | 50 | 42 | 2 | IPR014352 | |
| Domain | FERM_3 | 5.65e-03 | 50 | 42 | 2 | PS50057 | |
| Domain | Ubiquitin-rel_dom | 8.15e-03 | 184 | 42 | 3 | IPR029071 | |
| Pubmed | Proteome-scale mapping of binding sites in the unstructured regions of the human proteome. | 1.63e-10 | 430 | 45 | 10 | 35044719 | |
| Pubmed | Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability. | 7.91e-07 | 588 | 45 | 8 | 38580884 | |
| Pubmed | 1.05e-06 | 418 | 45 | 7 | 34709266 | ||
| Pubmed | Reciprocal interaction between SIRT6 and APC/C regulates genomic stability. | 1.48e-06 | 440 | 45 | 7 | 34244565 | |
| Pubmed | Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation. | 1.64e-06 | 2 | 45 | 2 | 23403927 | |
| Pubmed | Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone. | 1.64e-06 | 2 | 45 | 2 | 26793095 | |
| Pubmed | 1.64e-06 | 2 | 45 | 2 | 20332206 | ||
| Pubmed | 1.64e-06 | 2 | 45 | 2 | 7744883 | ||
| Pubmed | Active zone density is conserved during synaptic growth but impaired in aged mice. | 1.64e-06 | 2 | 45 | 2 | 21935939 | |
| Pubmed | 1.64e-06 | 2 | 45 | 2 | 27321892 | ||
| Pubmed | 1.64e-06 | 2 | 45 | 2 | 32493491 | ||
| Pubmed | Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. | 1.64e-06 | 2 | 45 | 2 | 25652077 | |
| Pubmed | 2.65e-06 | 21 | 45 | 3 | 16079250 | ||
| Pubmed | 4.98e-06 | 529 | 45 | 7 | 14621295 | ||
| Pubmed | 5.54e-06 | 347 | 45 | 6 | 17114649 | ||
| Pubmed | The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis. | 9.21e-06 | 218 | 45 | 5 | 33378226 | |
| Pubmed | 9.81e-06 | 4 | 45 | 2 | 20708588 | ||
| Pubmed | FAK/PYK2 promotes the Wnt/β-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3β. | 9.81e-06 | 4 | 45 | 2 | 26274564 | |
| Pubmed | 1.63e-05 | 5 | 45 | 2 | 12473661 | ||
| Pubmed | Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models. | 1.63e-05 | 5 | 45 | 2 | 30760710 | |
| Pubmed | The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery. | 1.98e-05 | 1203 | 45 | 9 | 29180619 | |
| Pubmed | Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. | 2.11e-05 | 125 | 45 | 4 | 32891193 | |
| Pubmed | 2.45e-05 | 6 | 45 | 2 | 19812333 | ||
| Pubmed | 2.45e-05 | 6 | 45 | 2 | 18786926 | ||
| Pubmed | 2.45e-05 | 6 | 45 | 2 | 14734538 | ||
| Pubmed | 2.92e-05 | 963 | 45 | 8 | 28671696 | ||
| Pubmed | 3.71e-05 | 486 | 45 | 6 | 20936779 | ||
| Pubmed | Proteomic analysis of in vivo phosphorylated synaptic proteins. | 4.53e-05 | 53 | 45 | 3 | 15572359 | |
| Pubmed | CoREST is an integral component of the CoREST- human histone deacetylase complex. | 4.56e-05 | 8 | 45 | 2 | 11171972 | |
| Pubmed | 5.86e-05 | 9 | 45 | 2 | 21144999 | ||
| Pubmed | Proximity labeling reveals dynamic changes in the SQSTM1 protein network. | 5.95e-05 | 322 | 45 | 5 | 39098523 | |
| Pubmed | Structural and functional consequences of NEDD8 phosphorylation. | 1.04e-04 | 70 | 45 | 3 | 34642328 | |
| Pubmed | Multiple roles of integrin-α3 at the neuromuscular junction. | 1.07e-04 | 12 | 45 | 2 | 28386022 | |
| Pubmed | Gene expression profiling of a mouse model of pancreatic islet dysmorphogenesis. | 1.07e-04 | 12 | 45 | 2 | 18297134 | |
| Pubmed | A central chaperone-like role for 14-3-3 proteins in human cells. | 1.11e-04 | 861 | 45 | 7 | 36931259 | |
| Pubmed | 1.27e-04 | 13 | 45 | 2 | 16469706 | ||
| Pubmed | ADAM10 hyperactivation acts on piccolo to deplete synaptic vesicle stores in Huntington's disease. | 1.37e-04 | 202 | 45 | 4 | 33601422 | |
| Pubmed | 1.47e-04 | 14 | 45 | 2 | 21228161 | ||
| Pubmed | 1.47e-04 | 14 | 45 | 2 | 16452088 | ||
| Pubmed | Integrin signalling regulates YAP and TAZ to control skin homeostasis. | 1.70e-04 | 15 | 45 | 2 | 26989177 | |
| Pubmed | 2.06e-04 | 225 | 45 | 4 | 12168954 | ||
| Pubmed | 2.47e-04 | 18 | 45 | 2 | 12493763 | ||
| Pubmed | Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. | 3.62e-04 | 475 | 45 | 5 | 31040226 | |
| Pubmed | 3.73e-04 | 263 | 45 | 4 | 34702444 | ||
| Pubmed | 4.01e-04 | 268 | 45 | 4 | 33640491 | ||
| Pubmed | 4.07e-04 | 23 | 45 | 2 | 17239249 | ||
| Pubmed | A High-Density Map for Navigating the Human Polycomb Complexome. | 4.37e-04 | 495 | 45 | 5 | 27705803 | |
| Pubmed | 4.52e-04 | 1084 | 45 | 7 | 11544199 | ||
| Pubmed | HENA, heterogeneous network-based data set for Alzheimer's disease. | 5.11e-04 | 120 | 45 | 3 | 31413325 | |
| Pubmed | Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. | 6.06e-04 | 28 | 45 | 2 | 24462114 | |
| Pubmed | 6.60e-04 | 131 | 45 | 3 | 28634551 | ||
| Pubmed | 6.90e-04 | 133 | 45 | 3 | 15144186 | ||
| Pubmed | 6.98e-04 | 549 | 45 | 5 | 38280479 | ||
| Pubmed | 7.43e-04 | 31 | 45 | 2 | 29846670 | ||
| Pubmed | 7.43e-04 | 31 | 45 | 2 | 25996949 | ||
| Pubmed | 7.43e-04 | 31 | 45 | 2 | 15217342 | ||
| Pubmed | 7.43e-04 | 31 | 45 | 2 | 26678539 | ||
| Pubmed | 7.92e-04 | 32 | 45 | 2 | 26142281 | ||
| Pubmed | Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. | 7.92e-04 | 32 | 45 | 2 | 26928066 | |
| Pubmed | 8.43e-04 | 33 | 45 | 2 | 27416896 | ||
| Pubmed | 8.94e-04 | 34 | 45 | 2 | 23293290 | ||
| Pubmed | A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal. | 9.04e-04 | 146 | 45 | 3 | 23892456 | |
| Pubmed | 9.96e-04 | 151 | 45 | 3 | 17043677 | ||
| Pubmed | 1.10e-03 | 608 | 45 | 5 | 16713569 | ||
| Pubmed | SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. | 1.12e-03 | 353 | 45 | 4 | 27545878 | |
| Interaction | YWHAG interactions | APC TAB2 UBAP2 WNK1 PTK2 SIMC1 HJURP RUSC2 USP24 CCSER2 PSD4 SYNGAP1 | 7.69e-06 | 1248 | 43 | 12 | int:YWHAG |
| Interaction | SIRT6 interactions | 4.70e-05 | 628 | 43 | 8 | int:SIRT6 | |
| Interaction | SLC35G1 interactions | 5.17e-05 | 34 | 43 | 3 | int:SLC35G1 | |
| Interaction | RCOR1 interactions | 7.65e-05 | 494 | 43 | 7 | int:RCOR1 | |
| Interaction | PHF21A interactions | 8.34e-05 | 343 | 43 | 6 | int:PHF21A | |
| Cytoband | 1p13.3 | 4.71e-05 | 69 | 46 | 3 | 1p13.3 | |
| Cytoband | Ensembl 112 genes in cytogenetic band chr1p13 | 1.26e-03 | 211 | 46 | 3 | chr1p13 | |
| Cytoband | 9p13.3 | 2.60e-03 | 75 | 46 | 2 | 9p13.3 | |
| GeneFamily | Neuroblastoma breakpoint family | 8.71e-06 | 23 | 32 | 3 | 662 | |
| GeneFamily | Zinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases | 3.14e-04 | 15 | 32 | 2 | 26 | |
| GeneFamily | Ankyrin repeat domain containing|FERM domain containing | 3.53e-03 | 50 | 32 | 2 | 1293 | |
| GeneFamily | Armadillo repeat containing|Protein phosphatase 1 regulatory subunits | 3.95e-03 | 181 | 32 | 3 | 694 | |
| GeneFamily | PHD finger proteins | 1.10e-02 | 90 | 32 | 2 | 88 | |
| Coexpression | BUSSLINGER_GASTRIC_IMMUNE_CELLS | PCNX1 ZNF683 TAB2 ZNF217 SIN3A KMT2E WNK1 WAC MYLIP USP24 CCSER2 PSD4 | 4.25e-06 | 1492 | 44 | 12 | M40023 |
| Coexpression | GSE7460_WT_VS_FOXP3_HET_ACT_WITH_TGFB_TCONV_UP | 2.10e-05 | 200 | 44 | 5 | M5711 | |
| CoexpressionAtlas | FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4 | 1.85e-05 | 595 | 42 | 8 | Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4 | |
| CoexpressionAtlas | FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#3 | 3.11e-05 | 185 | 42 | 5 | Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K3 | |
| CoexpressionAtlas | FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2 | 1.08e-04 | 564 | 42 | 7 | Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2 | |
| Drug | Pyrvinium pamoate [3546-41-6]; Down 200; 3.4uM; PC3; HT_HG-U133A | 1.97e-06 | 195 | 44 | 6 | 6339_DN | |
| Disease | cerebellar volume measurement | 6.95e-05 | 52 | 45 | 3 | EFO_0020864 | |
| Disease | Neurodevelopmental Disorders | 3.91e-04 | 93 | 45 | 3 | C1535926 | |
| Disease | Intellectual Disability | 5.79e-04 | 447 | 45 | 5 | C3714756 | |
| Disease | Mental Retardation, Psychosocial | 1.26e-03 | 139 | 45 | 3 | C0025363 | |
| Disease | Profound Mental Retardation | 1.26e-03 | 139 | 45 | 3 | C0020796 | |
| Disease | Mental deficiency | 1.26e-03 | 139 | 45 | 3 | C0917816 | |
| Disease | autism spectrum disorder (implicated_via_orthology) | 1.62e-03 | 152 | 45 | 3 | DOID:0060041 (implicated_via_orthology) | |
| Disease | developmental disorder of mental health (implicated_via_orthology) | 2.56e-03 | 49 | 45 | 2 | DOID:0060037 (implicated_via_orthology) | |
| Disease | hepatocellular carcinoma (implicated_via_orthology) | 2.56e-03 | 49 | 45 | 2 | DOID:684 (implicated_via_orthology) |
| Peptide | Gene | Start | Entry |
|---|---|---|---|
| NTSSNQSKNGTPFPR | 226 | Q6N043 | |
| KHSRQSNNSHSPLPS | 1101 | Q9NZJ5 | |
| HSQNPNLHKSLASSP | 976 | Q01954 | |
| QPSLHHPSTNQNQTK | 51 | Q9P2D1 | |
| KTNPTHSATRPQQTS | 526 | Q8NCD3 | |
| SHNPSNSNQPHRSTK | 216 | Q96M43 | |
| QSPKRHSISHSPNSN | 376 | Q9H1A4 | |
| TTAPRSKSQQQLHSP | 231 | Q9UPA5 | |
| SKSQQQLHSPALSPA | 236 | Q9UPA5 | |
| NSSSLKHSPNQATNQ | 181 | A0A1B0GUA6 | |
| KSHSSQSSQQSPKPS | 4836 | Q9Y6V0 | |
| PGNTLSPANNSHSRK | 2226 | Q96RV3 | |
| KNNSQPQSLLPSTSS | 601 | A0A1B0GTH6 | |
| QSKSQVPHASSQPRS | 21 | Q9NTX9 | |
| QSSPSSHSNHIPQLQ | 1296 | Q8IZD2 | |
| LSKNHPPQTHVRNSS | 1411 | Q8IZD2 | |
| RNNQSPSHSPLKSSE | 341 | Q8WY64 | |
| PRKKQNSNSQSTPGS | 486 | Q96HA1 | |
| QQPSQTHRSHPGKTN | 811 | Q9H7U1 | |
| LPTSNNRHNPTGSEK | 626 | Q8IYE1 | |
| HSQSSSQNSDPSRPL | 756 | Q8IZU9 | |
| TSEPSHKNIQRSTPN | 116 | Q9NQ60 | |
| TKNTNQNSSAHPPHL | 246 | Q9Y3Y4 | |
| TRPSNANHLSPQALK | 881 | Q8N2Y8 | |
| LTPSNLNNKHNSNIT | 566 | Q6P4F7 | |
| ASNPLSHTSSQQPNQ | 261 | Q9NYJ8 | |
| NTLSPSQNKTASHPQ | 441 | O75019 | |
| SHNPSNSNQPHRSTK | 216 | Q86XG9 | |
| SHNPSNSNQPHRSTK | 216 | Q5VWK0 | |
| LDPNLNHTPNSSTKT | 6 | Q05397 | |
| VNSHLPGSPKQNRST | 136 | Q8NDX1 | |
| SSHPSSQPNLTKNTN | 646 | Q8NDZ2 | |
| SKPSQLQAHTPASQQ | 251 | Q96ST3 | |
| NSHSSNPSNNPSKTS | 111 | Q9BTA9 | |
| TNSSPKHNNTSRLPN | 1901 | Q8IWZ3 | |
| PSSNAKRQNQLHPSS | 1221 | P25054 | |
| LHPSSAQSRSGQPQK | 1231 | P25054 | |
| QNSLSSAHNSSPCPN | 101 | Q6UXN8 | |
| SSRQRQQQPKSNSHA | 1656 | Q7KZ85 | |
| SGQRSQPSSLQPKSQ | 1091 | Q5T6F2 | |
| PSITKQHSQTPSTLN | 1131 | Q96PV0 | |
| LQKQQHLCSPSSSPS | 416 | Q96BW9 | |
| PAHPSSNSTLNQARN | 41 | Q6X4U4 | |
| SPSLSSKQQHQPSAS | 1141 | Q9UPU5 | |
| QTHQAGPSLSSQKPR | 1706 | Q9UL36 | |
| STLAPSNLKSHRPQQ | 811 | O75362 | |
| HSPHQLSSKSLPSQN | 2031 | Q9H4A3 | |
| SSHNSSSPPPLQNRK | 151 | Q8IZ20 | |
| PKRVQPAQNHSSLSN | 56 | Q8TDW0 | |
| IKQTPGHRRNPSNQS | 1091 | Q9ULV0 |