Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity

NANOGP8 NANOG

1.09e-044862GO:0001010
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

FZD4 IGF2R EGF EGFR FZD5

2.08e-0579885GO:0030669
GeneOntologyCellularComponentclathrin-coated vesicle

FZD4 IGF2R VWF EGF EGFR FZD5 ASTN2

6.41e-05237887GO:0030136
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

FZD4 IGF2R EGF EGFR FZD5

6.80e-05101885GO:0045334
GeneOntologyCellularComponentRad51B-Rad51C-Rad51D-XRCC2 complex

RAD51C RAD51B

1.05e-044882GO:0033063
GeneOntologyCellularComponentanchoring junction

FZD4 TRAF4 IGF2R PDLIM3 HMCN1 PDLIM1 EGFR ARHGAP31 FZD5 DUOX2 IGSF21 ITGB5 RPL8

2.15e-049768813GO:0070161
GeneOntologyCellularComponentmultivesicular body, internal vesicle

EGFR PMEL

2.60e-046882GO:0097487
GeneOntologyCellularComponentDNA recombinase mediator complex

RAD51C RAD51B

3.63e-047882GO:0033061
GeneOntologyCellularComponentclathrin-coated vesicle membrane

FZD4 IGF2R EGF EGFR FZD5

3.94e-04147885GO:0030665
GeneOntologyCellularComponentcoated vesicle

FZD4 IGF2R VWF EGF EGFR FZD5 ASTN2

8.14e-04360887GO:0030135
DomainVWC_out

NELL1 NELL2 FCGBP VWF MUC6

1.92e-0819855SM00215
DomainEGF

NELL1 NELL2 FCGBP EGF HMCN1 SLIT3 AGRN ITGB5 FBN3

1.22e-06235859SM00181
DomainVWF_dom

NELL1 NELL2 FCGBP VWF MUC6

1.29e-0642855IPR001007
DomainEGF_CA

NELL1 NELL2 EGF HMCN1 SLIT3 AGRN FBN3

1.38e-06122857SM00179
DomainEGF-like_Ca-bd_dom

NELL1 NELL2 EGF HMCN1 SLIT3 AGRN FBN3

1.54e-06124857IPR001881
DomainEGF_1

NELL1 NELL2 EGF HMCN1 SLIT3 ASTN2 AGRN ITGB5 FBN3

2.39e-06255859PS00022
DomainEGF_2

NELL1 NELL2 EGF HMCN1 SLIT3 ASTN2 AGRN ITGB5 FBN3

3.27e-06265859PS01186
DomainEGF_Ca-bd_CS

NELL1 NELL2 EGF HMCN1 SLIT3 FBN3

5.27e-0697856IPR018097
DomainEGF_CA

NELL1 NELL2 EGF HMCN1 SLIT3 FBN3

5.94e-0699856PS01187
DomainGrowth_fac_rcpt_

NELL1 NELL2 EGF HMCN1 EGFR SLIT3 FBN3

7.09e-06156857IPR009030
DomainEGF-type_Asp/Asn_hydroxyl_site

NELL1 NELL2 EGF HMCN1 SLIT3 FBN3

8.81e-06106856IPR000152
DomainEGF_3

NELL1 NELL2 EGF HMCN1 SLIT3 ASTN2 AGRN FBN3

1.17e-05235858PS50026
DomainEGF-like_dom

NELL1 NELL2 FCGBP EGF HMCN1 SLIT3 AGRN FBN3

1.77e-05249858IPR000742
DomainTIL

FCGBP VWF MUC6

1.94e-0512853PF01826
DomainC8

FCGBP VWF MUC6

1.94e-0512853PF08742
DomainEGF

EGF HMCN1 SLIT3 AGRN ITGB5 FBN3

2.37e-05126856PF00008
DomainEGF-like_CS

NELL1 NELL2 EGF HMCN1 SLIT3 AGRN ITGB5 FBN3

2.48e-05261858IPR013032
DomainUnchr_dom_Cys-rich

FCGBP VWF MUC6

2.52e-0513853IPR014853
DomainC8

FCGBP VWF MUC6

2.52e-0513853SM00832
DomainVWC

NELL1 NELL2 FCGBP VWF

2.62e-0538854SM00214
DomainTIL_dom

FCGBP VWF MUC6

3.19e-0514853IPR002919
DomainEGF_CA

NELL1 NELL2 EGF HMCN1 FBN3

4.52e-0586855PF07645
DomainLamG

NELL1 NELL2 SLIT3 AGRN

4.72e-0544854SM00282
DomainVWD

FCGBP VWF MUC6

4.88e-0516853SM00216
DomainVWF_type-D

FCGBP VWF MUC6

4.88e-0516853IPR001846
DomainVWFD

FCGBP VWF MUC6

4.88e-0516853PS51233
DomainVWD

FCGBP VWF MUC6

4.88e-0516853PF00094
DomainZM

PDLIM3 PDLIM1

6.12e-053852SM00735
DomainZasp-like_motif

PDLIM3 PDLIM1

6.12e-053852IPR006643
DomainASX_HYDROXYL

NELL1 NELL2 EGF HMCN1 FBN3

9.30e-05100855PS00010
DomainCT

VWF SLIT3 MUC6

1.32e-0422853SM00041
DomainLaminin_G

NELL1 NELL2 SLIT3 AGRN

1.41e-0458854IPR001791
DomainCys_knot_C

VWF SLIT3 MUC6

1.95e-0425853IPR006207
DomainCTCK_2

VWF SLIT3 MUC6

1.95e-0425853PS01225
DomainVWC

NELL1 NELL2 VWF

2.74e-0428853PF00093
DomainDUF4749

PDLIM3 PDLIM1

3.03e-046852PF15936
DomainRad51_DMC1_RadA

RAD51C RAD51B

3.03e-046852IPR033925
DomainDNA_recomb/repair_RecA-like

RAD51C RAD51B

3.03e-046852IPR016467
DomainDUF4749

PDLIM3 PDLIM1

3.03e-046852IPR031847
DomainDNA_recomb/repair_Rad51_C

RAD51C RAD51B

4.24e-047852IPR013632
DomainRad51

RAD51C RAD51B

4.24e-047852PF08423
DomainRecA_ATP-bd

RAD51C RAD51B

4.24e-047852IPR020588
DomainRECA_2

RAD51C RAD51B

4.24e-047852PS50162
DomainVWFC_1

NELL1 NELL2 VWF

5.83e-0436853PS01208
DomainVWFC_2

NELL1 NELL2 VWF

6.84e-0438853PS50184
DomainLaminin_G_2

NELL1 NELL2 SLIT3

7.96e-0440853PF02210
DomainZnf_RING_CS

CBLL1 RNF144B TRAF4 RNF41 RBCK1

8.90e-04163855IPR017907
Domain-

NELL1 NELL2 SLIT3 AGRN

9.28e-04958542.60.120.200
DomainFol_N

FCGBP AGRN

1.10e-0311852IPR003645
Domain-

EGF HMCN1

1.10e-03118522.40.155.10
DomainGFP-like

EGF HMCN1

1.10e-0311852IPR023413
DomainFrizzled

FZD4 FZD5

1.10e-0311852IPR000539
DomainFrizzled

FZD4 FZD5

1.10e-0311852PF01534
DomainFOLN

FCGBP AGRN

1.10e-0311852SM00274
DomainFrizzled

FZD4 FZD5

1.10e-0311852SM01330
DomainIBR

RNF144B RBCK1

1.80e-0314852PF01485
Domain-

TRAF4 RNF41

1.80e-03148523.90.890.10
DomainIBR_dom

RNF144B RBCK1

2.07e-0315852IPR002867
DomainSIAH-type

TRAF4 RNF41

2.36e-0316852IPR013323
DomainFrizzled/SFRP

FZD4 FZD5

2.36e-0316852IPR015526
DomainGPCR_2-like

FZD4 FZD5 ADGRB2

2.58e-0360853IPR017981
DomainEGF_extracell

NELL1 NELL2 ITGB5

2.58e-0360853IPR013111
DomainEGF_2

NELL1 NELL2 ITGB5

2.58e-0360853PF07974
DomainG_PROTEIN_RECEP_F2_4

FZD4 FZD5 ADGRB2

2.71e-0361853PS50261
DomainTSP_1

HMCN1 ADGRB2 CFP

2.97e-0363853PF00090
DomainCTCK_1

VWF SLIT3

2.99e-0318852PS01185
DomainTSP1

HMCN1 ADGRB2 CFP

3.24e-0365853SM00209
DomainTSP1_rpt

HMCN1 ADGRB2 CFP

3.24e-0365853IPR000884
DomainTSP1

HMCN1 ADGRB2 CFP

3.24e-0365853PS50092
DomainFRI

FZD4 FZD5

3.69e-0320852SM00063
Domain-

FZD4 FZD5

4.06e-03218521.10.2000.10
PathwayBIOCARTA_ERBB3_PATHWAY

EGF EGFR RNF41

1.77e-066643MM1543
PathwayWP_ERK_PATHWAY_IN_HUNTINGTONS_DISEASE

EGF EGFR GRM1

5.80e-0517643M39564
PathwayBIOCARTA_ERBB3_PATHWAY

EGF EGFR

2.01e-045642M22018
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

EGF EGFR RNF41

2.15e-0426643MM15501
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_SIGNALING

EGF EGFR RNF41

3.00e-0429643M27756
PathwayBIOCARTA_EEA1_PATHWAY

EGF EGFR

3.01e-046642MM1577
PathwayBIOCARTA_EEA1_PATHWAY

EGF EGFR

4.20e-047642M22064
PathwayKEGG_MEDICUS_REFERENCE_EGF_JAK_STAT_SIGNALING_PATHWAY

EGF EGFR

4.20e-047642M47430
PathwayKEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_EGF_JAK_STAT_SIGNALING_PATHWAY

EGF EGFR

4.20e-047642M47431
PathwayWP_FLUOROPYRIMIDINE_ACTIVITY

DPYD MTHFR TYMP

4.83e-0434643M39612
PathwayREACTOME_SIGNALING_BY_RNF43_MUTANTS

FZD4 FZD5

5.58e-048642M27433
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

EGF EGFR

5.58e-048642M47498
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY

EGF EGFR

7.16e-049642M47392
PathwayREACTOME_EGFR_INTERACTS_WITH_PHOSPHOLIPASE_C_GAMMA

EGF EGFR

7.16e-049642M27133
PathwayREACTOME_EGFR_INTERACTS_WITH_PHOSPHOLIPASE_C_GAMMA

EGF EGFR

7.16e-049642MM14853
PathwayWP_BLADDER_CANCER

EGF EGFR TYMP

7.82e-0440643M39523
PathwayREACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO

NELL2 SLIT3

8.92e-0410642M27348
PathwayKEGG_BLADDER_CANCER

EGF EGFR TYMP

9.03e-0442643M19096
PathwayREACTOME_SIGNALING_BY_ERBB2

EGF EGFR RNF41

1.03e-0344643MM14520
PathwayBIOCARTA_CBL_PATHWAY

EGF EGFR

1.09e-0311642MM1360
PathwayBIOCARTA_EGFR_SMRTE_PATHWAY

EGF EGFR

1.09e-0311642M18837
PathwayKEGG_MEDICUS_REFERENCE_RAD51_DSDNA_DESTABILIZATION

RAD51C RAD51B

1.09e-0311642M47894
PathwayWP_UDPDERIVED_SUGARS_SYNTHESIS_IN_FIBROBLASTS

HK3 UGDH

1.09e-0311642M48094
PathwayBIOCARTA_EGFR_SMRTE_PATHWAY

EGF EGFR

1.09e-0311642MM1432
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY

EGF EGFR

1.09e-0311642M47436
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RASSF1_SIGNALING_PATHWAY

EGF EGFR

1.09e-0311642M47432
PathwayREACTOME_PYRIMIDINE_CATABOLISM

DPYD TYMP

1.09e-0311642MM15423
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

EGF EGFR

1.09e-0311642MM15478
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

FZD4 NANOGP8 FZD5 NANOG

1.13e-03101644MM15829
PathwayREACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS

FZD4 IGF2R EGF EGFR

1.18e-03102644MM15498
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

MST1 EGF EGFR

1.18e-0346643M239
PathwayBIOCARTA_KERATINOCYTE_PATHWAY

EGF EGFR MAP3K5

1.18e-0346643M19118
PathwayBIOCARTA_KERATINOCYTE_PATHWAY

EGF EGFR MAP3K5

1.18e-0346643MM1428
PathwayKEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

EGF EGFR

1.30e-0312642M47393
PathwayBIOCARTA_CBL_PATHWAY

EGF EGFR

1.30e-0312642M16973
PathwayREACTOME_PYRIMIDINE_CATABOLISM

DPYD TYMP

1.30e-0312642M10654
PathwayREACTOME_CARGO_RECOGNITION_FOR_CLATHRIN_MEDIATED_ENDOCYTOSIS

FZD4 IGF2R EGF EGFR

1.31e-03105644M27752
PathwayPID_AJDISS_2PATHWAY

CBLL1 EGF EGFR

1.33e-0348643M142
PathwayWP_TROP2_REGULATORY_SIGNALING

IGF2R EGFR TACSTD2

1.42e-0349643M46458
PathwayREACTOME_SIGNALING_BY_ERBB2

EGF EGFR RNF41

1.50e-0350643M553
PathwayREACTOME_ERBB2_ACTIVATES_PTK6_SIGNALING

EGF EGFR

1.53e-0313642M27729
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_JNK_SIGNALING_PATHWAY

EGF EGFR

1.53e-0313642M47594
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

EGF EGFR

1.53e-0313642MM15320
PathwayREACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING

EGF EGFR

1.53e-0313642MM14701
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_SOST_LRP4

FZD4 FZD5

1.78e-0314642M47834
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY

EGF EGFR

1.78e-0314642M47536
PathwayREACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING

EGF EGFR

1.78e-0314642M719
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

EGF EGFR

1.78e-0314642MM14761
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

EGF EGFR

1.78e-0314642MM14531
PathwayWP_ESC_PLURIPOTENCY_PATHWAYS

FZD4 EGF EGFR FZD5

1.89e-03116644MM15863
PathwayWP_EMBRYONIC_STEM_CELL_PLURIPOTENCY_PATHWAYS

FZD4 EGF EGFR FZD5

1.95e-03117644M39530
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

MST1 EGF EGFR

1.98e-0355643M47952
PathwayPID_ERBB_NETWORK_PATHWAY

EGF EGFR

2.05e-0315642M201
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_EGFRVIII

EGF EGFR

2.05e-0315642M29701
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY

EGF EGFR

2.05e-0315642M47389
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CAMK_SIGNALING_PATHWAY

EGF EGFR

2.05e-0315642M47385
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY

EGF EGFR

2.05e-0315642M47382
PathwayREACTOME_ERBB2_REGULATES_CELL_MOTILITY

EGF EGFR

2.05e-0315642M27608
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY

EGF EGFR

2.05e-0315642M47495
PathwayWP_BIOMARKERS_FOR_PYRIMIDINE_METABOLISM_DISORDERS

DPYD TYMP

2.05e-0315642M39841
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY

EGF EGFR

2.34e-0316642M47363
PathwayBIOCARTA_SPRY_PATHWAY

EGF EGFR

2.34e-0316642MM1500
PathwayKEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY

EGF EGFR

2.34e-0316642M47381
PathwayKEGG_MEDICUS_REFERENCE_WNT5A_ROR_SIGNALING_PATHWAY

FZD4 FZD5

2.34e-0316642M47823
PathwayREACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING

EGF EGFR

2.34e-0316642M562
PathwayREACTOME_PI3K_EVENTS_IN_ERBB2_SIGNALING

EGF EGFR

2.34e-0316642M570
PathwayREACTOME_SIGNALING_BY_ERBB2_ECD_MUTANTS

EGF EGFR

2.34e-0316642M29847
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_CALCINEURIN_SIGNALING_PATHWAY

EGF EGFR

2.34e-0316642M47449
PathwayBIOCARTA_SPRY_PATHWAY

EGF EGFR

2.64e-0317642M1389
PathwayREACTOME_GAB1_SIGNALOSOME

EGF EGFR

2.64e-0317642MM14700
PathwayREACTOME_GAB1_SIGNALOSOME

EGF EGFR

2.64e-0317642M10450
PathwayBIOCARTA_CARDIACEGF_PATHWAY

EGF EGFR

2.96e-0318642M7552
PathwayBIOCARTA_CARDIACEGF_PATHWAY

EGF EGFR

2.96e-0318642MM1479
PathwayKEGG_MEDICUS_REFERENCE_WNT_SIGNALING_MODULATION_LGR_RSPO

FZD4 FZD5

3.30e-0319642M47833
PathwayREACTOME_SIGNALING_BY_NOTCH3

EGF EGFR

3.30e-0319642MM15594
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_LIGAND_RESPONSIVE_EGFR_CANCER_VARIANTS

EGF EGFR

3.30e-0319642M559
PathwayBIOCARTA_MCALPAIN_PATHWAY

EGF EGFR

3.30e-0319642MM1434
PathwayBIOCARTA_MCALPAIN_PATHWAY

EGF EGFR

3.30e-0319642M8719
PathwayWP_PHYSICOCHEMICAL_FEATURES_AND_TOXICITYASSOCIATED_PATHWAYS

FZD4 EGFR FZD5

3.33e-0366643M39642
PathwayWP_PYRIMIDINE_METABOLISM_AND_RELATED_DISEASES

DPYD TYMP

3.66e-0320642M39765
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD4 FZD5

3.66e-0320642MM15155
PathwayREACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS

FZD4 IGF2R EGF EGFR

3.93e-03142644MM15499
PathwayWP_EXTRACELLULAR_VESICLES_IN_THE_CROSSTALK_OF_CARDIAC_CELLS

EGF EGFR

4.03e-0321642M39735
PathwayREACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION

FZD4 FZD5

4.03e-0321642M27401
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_ACTIN_SIGNALING_PATHWAY

EGF EGFR

4.03e-0321642M47722
PathwayREACTOME_CLATHRIN_MEDIATED_ENDOCYTOSIS

FZD4 IGF2R EGF EGFR

4.23e-03145644M27753
PathwayREACTOME_SHC1_EVENTS_IN_ERBB2_SIGNALING

EGF EGFR

4.42e-0322642M26929
Pubmed

Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.

HK3 EGFR ADGRB2 MAP3K5

1.51e-071989412543931
Pubmed

SNPs in genes coding for ROS metabolism and signalling in association with docetaxel clearance.

DPYD EGF EGFR

1.35e-06989320157331
Pubmed

Mga is essential for the survival of pluripotent cells during peri-implantation development.

NANOGP8 NANOG MGA

1.35e-06989325516968
Pubmed

High glucose promotes pancreatic cancer cell proliferation via the induction of EGF expression and transactivation of EGFR.

EGF EGFR

6.48e-06289222087246
Pubmed

Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking.

EGF EGFR

6.48e-06289212162747
Pubmed

Ontogenesis and distribution of epidermal growth factor immunoreactivity and binding activity in the mouse fetal and neonatal tissues.

EGF EGFR

6.48e-0628927951532
Pubmed

Conformational stability of the epidermal growth factor (EGF) receptor as influenced by glycosylation, dimerization and EGF hormone binding.

EGF EGFR

6.48e-06289228019699
Pubmed

The role of EGF-EGFR signalling pathway in hepatocellular carcinoma inflammatory microenvironment.

EGF EGFR

6.48e-06289224268047
Pubmed

FRET detects lateral interaction between transmembrane domain of EGF receptor and ganglioside GM3 in lipid bilayers.

EGF EGFR

6.48e-06289233933428
Pubmed

pH dependence of ligand-induced human epidermal growth factor receptor activation investigated by molecular dynamics simulations.

EGF EGFR

6.48e-06289227179806
Pubmed

EGF ligand fused to truncated Pseudomonas aeruginosa exotoxin A specifically targets and inhibits EGFR‑positive cancer cells.

EGF EGFR

6.48e-06289230226622
Pubmed

The +61 A-G polymorphism of the epidermal growth factor gene is not associated with occurrence of non-melanocytic skin tumors in transplant recipients.

EGF EGFR

6.48e-06289217223314
Pubmed

Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2.

NELL1 NELL2

6.48e-06289210548494
Pubmed

Epigenetic role of epidermal growth factor expression and signalling in embryonic mouse lung morphogenesis.

EGF EGFR

6.48e-0628921728582
Pubmed

Human adult epidermal melanocytes cultured without chemical mitogens express the EGF receptor and respond to EGF.

EGF EGFR

6.48e-06289217334773
Pubmed

Determining the geometry of oligomers of the human epidermal growth factor family on cells with <10 nm resolution.

EGF EGFR

6.48e-06289226009168
Pubmed

Functional effects of glycosylation at Asn-579 of the epidermal growth factor receptor.

EGF EGFR

6.48e-06289216274239
Pubmed

Association study between epidermal growth factor receptor and epidermal growth factor polymorphisms and endometriosis in a Japanese population.

EGF EGFR

6.48e-06289217852426
Pubmed

An association between EGF and EGFR gene polymorphisms with gastric cancer in a Chinese Han population.

EGF EGFR

6.48e-06289222534548
Pubmed

Epidermal growth factor as a biologic switch in hair growth cycle.

EGF EGFR

6.48e-06289212714603
Pubmed

Dynamic distribution of epidermal growth factor during mouse embryo peri-implantation.

EGF EGFR

6.48e-06289212967642
Pubmed

Engineered epidermal growth factor mutants with faster binding on-rates correlate with enhanced receptor activation.

EGF EGFR

6.48e-06289221439278
Pubmed

Functional evidence that the self-renewal gene NANOG regulates human tumor development.

NANOGP8 NANOG

6.48e-06289219415763
Pubmed

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation.

EGF EGFR

6.48e-0628922790960
Pubmed

Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers.

DPYD TYMP

6.48e-06289215069545
Pubmed

Epidermal growth factor receptor (EGFR) signaling regulates global metabolic pathways in EGFR-mutated lung adenocarcinoma.

EGF EGFR

6.48e-06289224928511
Pubmed

Weak power frequency magnetic field acting similarly to EGF stimulation, induces acute activations of the EGFR sensitive actin cytoskeleton motility in human amniotic cells.

EGF EGFR

6.48e-06289224505297
Pubmed

Polyubiquitination of the epidermal growth factor receptor occurs at the plasma membrane upon ligand-induced activation.

EGF EGFR

6.48e-06289210788520
Pubmed

Structure-function analysis of Nel, a thrombospondin-1-like glycoprotein involved in neural development and functions.

NELL1 NELL2

6.48e-06289222157752
Pubmed

Biological and biochemical activities of a chimeric epidermal growth factor-Elk receptor tyrosine kinase.

EGF EGFR

6.48e-0628928413296
Pubmed

Clinical significance of EGF and EGFR expression changes in cryptorchid boys.

EGF EGFR

6.48e-06289212508124
Pubmed

Role of N-glycosylation in EGFR ectodomain ligand binding.

EGF EGFR

6.48e-06289228486782
Pubmed

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab.

EGF EGFR

6.48e-06289215837620
Pubmed

Taiwan cobra cardiotoxin III suppresses EGF/EGFR-mediated epithelial-to-mesenchymal transition and invasion of human breast cancer MDA-MB-231 cells.

EGF EGFR

6.48e-06289226774845
Pubmed

EGF-liposomes promote efficient EGFR targeting in xenograft colocarcinoma model.

EGF EGFR

6.48e-06289226892017
Pubmed

Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells.

EGF EGFR

6.48e-06289225483192
Pubmed

Alteration of the serum levels of the epidermal growth factor receptor and its ligands in patients with non-small cell lung cancer and head and neck carcinoma.

EGF EGFR

6.48e-06289217453000
Pubmed

Cell Force-Driven Basement Membrane Disruption Fuels EGF- and Stiffness-Induced Invasive Cell Dissemination from Benign Breast Gland Acini.

EGF EGFR

6.48e-06289233921304
Pubmed

FGFs in endochondral skeletal development.

EGF EGFR

6.48e-06289220564212
Pubmed

Heterogeneity in EGF-binding affinities arises from negative cooperativity in an aggregating system.

EGF EGFR

6.48e-06289218165319
Pubmed

Diminished salivary epidermal growth factor secretion: a link between Sjögren's syndrome and autoimmune gastritis?

EGF EGFR

6.48e-06289226399281
Pubmed

[Expression of epidermal growth factor receptor in patients with insulin resistance and seborrheic keratomas].

EGF EGFR

6.48e-06289228791994
Pubmed

Role of epidermal growth factor gene in the development of pancreatic cancer and efficiency of inhibitors of this gene in the treatment of pancreatic carcinoma.

EGF EGFR

6.48e-06289219110611
Pubmed

Effects of epidermal growth factor on preimplantation mouse embryos.

EGF EGFR

6.48e-0628929285326
Pubmed

EGF abrogation-induced fusilli-form dysmorphogenesis of Meckel's cartilage during embryonic mouse mandibular morphogenesis in vitro.

EGF EGFR

6.48e-0628928076525
Pubmed

Receptor overexpression or inhibition alters cell surface dynamics of EGF-EGFR interaction: new insights from real-time single molecule analysis.

EGF EGFR

6.48e-06289219014905
Pubmed

MASTL regulates EGFR signaling to impact pancreatic cancer progression.

EGFR MASTL

6.48e-06289234331012
Pubmed

Searching for EGF Fragments Recreating the Outer Sphere of the Growth Factor Involved in Receptor Interactions.

EGF EGFR

6.48e-06289238338748
Pubmed

Robust co-regulation of tyrosine phosphorylation sites on proteins reveals novel protein interactions.

PDLIM1 EGFR

6.48e-06289222851037
Pubmed

No association between epidermal growth factor and epidermal growth factor receptor polymorphisms and nasopharyngeal carcinoma.

EGF EGFR

6.48e-06289218722874
Pubmed

Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.

NELL1 NELL2

6.48e-06289225726761
Pubmed

Thymidine phosphorylase levels and dihydropyrimidine dehydrogenase levels in non-small cell lung cancer tissues.

DPYD TYMP

6.48e-06289216969493
Pubmed

Epidermal growth factor mutant with wild-type affinity for both ErbB1 and ErbB3.

EGF EGFR

6.48e-06289216584205
Pubmed

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization.

EGF EGFR

6.48e-06289212620237
Pubmed

Potent SHC tyrosine phosphorylation by epidermal growth factor at low receptor density or in the absence of receptor autophosphorylation sites.

EGF EGFR

6.48e-0628928036006
Pubmed

Polymorphism in Sp1 recognition site of the EGF receptor gene promoter and risk of glioblastoma.

EGF EGFR

6.48e-06289216885506
Pubmed

Abnormal expression of epidermal growth factor and its receptor in the forebrain and serum of schizophrenic patients.

EGF EGFR

6.48e-06289212192610
Pubmed

B-vitamin intake, one-carbon metabolism, and survival in a population-based study of women with breast cancer.

MTHFR BHMT

6.48e-06289218708404
Pubmed

The epidermal growth factor.

EGF EGFR

6.48e-0628927640657
Pubmed

Shedding of soluble epidermal growth factor receptor (sEGFR) is mediated by a metalloprotease/fibronectin/integrin axis and inhibited by cetuximab.

EGF EGFR

6.48e-06289223731208
Pubmed

Maternal birth weight is associated with milk epidermal growth factor in Filipino women.

EGF EGFR

6.48e-06289232057154
Pubmed

The miR-200 family regulates the epithelial-mesenchymal transition induced by EGF/EGFR in anaplastic thyroid cancer cells.

EGF EGFR

6.48e-06289222797360
Pubmed

Detection of epidermal growth factor-urogastrone and its receptor during fetal mouse development.

EGF EGFR

6.48e-0628926248866
Pubmed

The distribution of epidermal growth factor binding sites in the developing mouse palate.

EGF EGFR

6.48e-0628928292539
Pubmed

DPYD*2A and MTHFR C677T predict toxicity and efficacy, respectively, in patients on chemotherapy with 5-fluorouracil for colorectal cancer.

DPYD MTHFR

6.48e-06289229134491
Pubmed

The neuronal EGF-related genes NELL1 and NELL2 are expressed in hemopoietic cells and developmentally regulated in the B lineage.

NELL1 NELL2

6.48e-06289210231576
Pubmed

Translocation of Epidermal Growth Factor (EGF) to the nucleus has distinct kinetics between adipose tissue-derived mesenchymal stem cells and a mesenchymal cancer cell lineage.

EGF EGFR

6.48e-06289229277356
Pubmed

Interaction of EGFR 497Arg>Lys with EGF +61A>G polymorphism: modulation of risk in esophageal cancer.

EGF EGFR

6.48e-06289218773861
Pubmed

Nucleic Acid Metabolizing Enzyme Levels Predict Chemotherapy Effects in Advanced and Recurrent Colorectal Cancer.

DPYD MTHFR

6.48e-06289235345374
Pubmed

EGF receptor-ligand interaction generates extracellular hydrogen peroxide that inhibits EGFR-associated protein tyrosine phosphatases.

EGF EGFR

6.48e-06289215982634
Pubmed

Heterodimerization of the epidermal-growth-factor (EGF) receptor and ErbB2 and the affinity of EGF binding are regulated by different mechanisms.

EGF EGFR

6.48e-06289211336639
Pubmed

Activation of epidermal growth factor receptor by epidermal growth factor.

EGF EGFR

6.48e-0628928639530
Pubmed

Association between epidermal growth factor (EGF) and EGF receptor gene polymorphisms and end-stage renal disease and acute renal allograft rejection in a Korean population.

EGF EGFR

6.48e-06289231906817
Pubmed

The intracellular juxtamembrane domain of the epidermal growth factor (EGF) receptor is responsible for the allosteric regulation of EGF binding.

EGF EGFR

6.48e-06289219336395
Pubmed

Complex relationship between ligand binding and dimerization in the epidermal growth factor receptor.

EGF EGFR

6.48e-06289225453753
Pubmed

EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling.

EGF EGFR

6.48e-06289226609808
Pubmed

[Expression of epidermal growth factor receptor and concentrations of epidermal growth factor and melatonin in endometrial carcinoma].

EGF EGFR

6.48e-06289225416211
Pubmed

Amplification of the EGFR gene can be maintained and modulated by variation of EGF concentrations in in vitro models of glioblastoma multiforme.

EGF EGFR

6.48e-06289228934307
Pubmed

Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species.

NANOGP8 NANOG

6.48e-06289224598770
Pubmed

Differential expression of nanog1 and nanogp8 in colon cancer cells.

NANOGP8 NANOG

6.48e-06289222079639
Pubmed

[TRAF4 promotes lung cancer development by activating tyrosine kinase of EGFR].

TRAF4 EGFR

6.48e-06289239414598
Pubmed

Palmitoylation of the EGF receptor impairs signal transduction and abolishes high-affinity ligand binding.

EGF EGFR

6.48e-06289219196031
Pubmed

Effect of epidermal growth factor administration on the development of mouse salivary gland carcinomas.

EGF EGFR

6.48e-0628929890455
Pubmed

Role of epidermal growth factor and its receptor in chemotherapy-induced intestinal injury.

EGF EGFR

6.48e-06289211841993
Pubmed

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.

EGF EGFR

6.48e-06289221822280
Pubmed

Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats.

NELL1 NELL2

6.48e-0628928975702
Pubmed

Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events.

EGF EGFR

6.48e-06289225872475
Pubmed

Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency.

MTHFR BHMT

6.48e-06289215217352
Pubmed

EGF signalling amplification induced by dynamic clustering of EGFR.

EGF EGFR

6.48e-06289215485674
Pubmed

EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.

EGF EGFR

6.48e-06289224704591
Pubmed

Genetic variations in EGF and EGFR and glioblastoma outcome.

EGF EGFR

6.48e-06289220197289
Pubmed

EGF/EGFR Promotes Salivary Adenoid Cystic Carcinoma Cell Malignant Neural Invasion via Activation of PI3K/AKT and MEK/ERK Signaling.

EGF EGFR

6.48e-06289235410600
Pubmed

Sustained epidermal growth factor receptor levels and activation by tethered ligand binding enhances osteogenic differentiation of multi-potent marrow stromal cells.

EGF EGFR

6.48e-06289219544388
Pubmed

Association of epidermal growth factor and epidermal growth factor receptor polymorphisms with the risk of hepatitis B virus-related hepatocellular carcinoma in the population of North China.

EGF EGFR

6.48e-06289223790025
Pubmed

EGFR genomic gain and aberrant pathway signaling in pancreatic cancer patients.

EGF EGFR

6.48e-06289217950068
Pubmed

Expression of EGF, EGFR, and proliferation in placentas from pregnancies complicated with preeclampsia.

EGF EGFR

6.48e-06289227657362
Pubmed

TRAF4 binds to the juxtamembrane region of EGFR directly and promotes kinase activation.

TRAF4 EGFR

6.48e-06289230352854
Pubmed

Impact of epidermal growth factor single-nucleotide polymorphism on recurrence of hepatocellular carcinoma after hepatectomy in patients with chronic hepatitis C virus infection.

EGF EGFR

6.48e-06289224703510
Pubmed

Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.

NANOGP8 NANOG

6.48e-06289221136380
Pubmed

Modulation of focal adhesion constituents and their down-stream events by EGF: On the cross-talk of integrins and growth factor receptors.

EGF EGFR

6.48e-06289226079101
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD4 FZD5

5.27e-0411572286
CoexpressionNABA_ECM_GLYCOPROTEINS

NELL1 NELL2 VWF HMCN1 SLIT3 AGRN FBN3

4.82e-06196897M3008
CoexpressionGSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP

NELL2 EGF MOB3B AKAP13 LYST RPL8 MAP3K5

5.15e-06198897M3198
CoexpressionGSE3982_DC_VS_MAC_LPS_STIM_UP

NELL2 CFP SIGLEC1 MGA TACSTD2 CBR3 SEC14L1

5.50e-06200897M5387
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MID_MESOTHELIAL_CELL

MST1 NELL2 MTHFR FAM221A ADGRB2 ARHGAP29 CARD16 ALDH1A3 LYST AGRN ITGB5 FBN3 SEC14L1

1.99e-059558913M45680
CoexpressionMURARO_PANCREAS_ACINAR_CELL

TRAF4 PDLIM1 EGFR ANO6 FZD5 UGDH MOB3B DUOX2 TACSTD2 CHAC1 MAP3K5

3.78e-057328911M39174
CoexpressionGAO_LARGE_INTESTINE_24W_C2_MKI67POS_PROGENITOR

FZD4 VWF HMCN1 ARHGAP29 SEC14L1

4.24e-05113895M39153
CoexpressionNABA_CORE_MATRISOME

NELL1 NELL2 VWF HMCN1 SLIT3 AGRN FBN3

4.29e-05275897M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

NELL1 NELL2 VWF HMCN1 SLIT3 AGRN

4.87e-05191896MM17059
CoexpressionGSE40274_IRF4_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

HK3 DUOX2 TACSTD2 ITGB5 CHAC1

5.21e-05118895M9155
CoexpressionGSE7460_CTRL_VS_TGFB_TREATED_ACT_TCONV_UP

KCNQ5 FZD5 ARHGAP29 MOB3B LYST BHMT

6.11e-05199896M5694
CoexpressionGSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP

MST1 MIS18BP1 HK3 ALMS1 MOB3B CBR3

6.29e-05200896M7185
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP

MST1 KCNQ5 ARHGAP31 FZD5 MYT1 ADGRB2

6.29e-05200896M9181
CoexpressionFISCHER_DIRECT_P53_TARGETS_META_ANALYSIS

RAD51C RNF144B TRAF4 ASTN2 TNFRSF10D ALDH1A3 DNAI3

9.28e-05311897M61
CoexpressionHE_LIM_SUN_FETAL_LUNG_C7_COL20A1_POS_SCHWANN_CELL

HMCN1 PDLIM1 ARHGAP31 ALDH1A3

1.07e-0472894M45791
CoexpressionGSE12484_HEALTHY_VS_PERIDONTITIS_NEUTROPHILS_UP

NELL1 EGF ARHGAP29 MFSD2B CSMD2

1.13e-04139895M433
CoexpressionDELYS_THYROID_CANCER_UP

DPYD NELL2 PDLIM1 ALDH1A3 TACSTD2 AGRN ITGB5 MAP3K5

1.38e-04445898M3645
CoexpressionZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_UP

PARP10 HK3 ARHGAP31 MASTL CFP CARD16 SIGLEC1 TYMP LYST AGRN RBCK1 SEC14L1

1.58e-0410128912M40868
CoexpressionHUANG_DASATINIB_SENSITIVITY_UP

DPYD EGFR ARHGAP29 DENND2B

1.61e-0480894M3015
ToppCellproximal-Hematologic-Nonclassical_Monocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RNF144B MIS18BP1 HK3 CFP CARD16 TYMP LYST MUC6

5.87e-091968987e136975e5943d42d51d8cc91c912547ef79cf4d
ToppCellproximal-3-Hematologic-Nonclassical_Monocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RNF144B MIS18BP1 HK3 CFP CARD16 TYMP LYST MUC6

5.87e-09196898e426d02c6bcff2358a45e627cc86389070a4af25
ToppCellproximal-Hematologic-Nonclassical_Monocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

RNF144B MIS18BP1 HK3 CFP CARD16 TYMP LYST MUC6

5.87e-09196898439d695526714772971fd1a4a92b8b6a84eee1a4
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

PROK2 RNF144B DPYD HK3 CFP SIGLEC1 TYMP

1.46e-07198897ea34096bee852a7e996f097fa279381afa8f86ff
ToppCellNeuronal-Excitatory|Neuronal / cells hierarchy compared to all cells using T-Statistic

NELL1 DPYD NELL2 KCNQ5 SLIT3 AKAP13 GRM1

1.56e-072008974409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell(61)_LYVE1_Macrophage|World / shred on Cell_type and subtype

NELL1 NELL2 HK3 CFP SIGLEC1 IGSF21 ITGB5

1.91e-07206897711e961a9a03bfd2f0958bd14f25f7f207a2f2b5
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Penk_Fst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NELL2 PDLIM1 ARHGAP31 SLIT3 AKAP13 IGSF21

1.46e-06176896a1b9f8f199a028b3fa85de43fe96bc29f387bfd8
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 DPYD NELL2 SLIT3 GRM1 IGSF21

1.77e-0618289635b2a5625323bf0917214d3b82fafc4a8f5e75ff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 DPYD NELL2 SLIT3 GRM1 IGSF21

1.89e-061848969a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

FZD4 RNF144B VWF ARHGAP31 ARHGAP29 SEC14L1

2.08e-06187896fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

MST1 PDLIM3 EGFR SLIT3 UGDH ALDH1A3

2.21e-0618989679bb2593ad5d17f94b17972884241f03a0f43770
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 DPYD NELL2 KCNQ5 SLIT3 GRM1

2.21e-06189896a75226616340045b581d08429d2e123e041dee55
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 SLIT3 MOB3B ALDH1A3 DNAI3 MAP3K5

2.28e-0619089645df8fee00f8949937863159d7aa042e72748d9b
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NELL2 TRAF4 MYT1 UGDH PMEL IGSF21

2.28e-061908969b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NELL2 TRAF4 MYT1 UGDH PMEL IGSF21

2.28e-06190896d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

RNF144B VWF ARHGAP31 ARHGAP29 TNFRSF10D SEC14L1

2.35e-06191896c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCelldroplet-Heart-nan-18m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MST1 IGF2R VWF PDLIM3 HMCN1 ASTN2

2.42e-061928960b9b2eaed45456d7d74ce78a64ef4a26ac2458fb
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF144B HK3 CFP CARD16 TYMP LYST

2.49e-06193896cb0fb21510124883e716780bea46575620c366b8
ToppCellRA-08._Macrophage|World / Chamber and Cluster_Paper

RNF144B DPYD HK3 TYMP IGSF21 MUC6

2.49e-061938965fd22db1825d105709fcc0aa4955c99a117e3c82
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF144B HK3 CFP CARD16 TYMP LYST

2.49e-061938960c207879f994c227dcd1322faa69ec9e3749cdaa
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PDLIM3 HMCN1 PDLIM1 ANO6 SLIT3 TLCD5

2.49e-06193896ba6eb29478d16589172f48f9992e5116328c81d6
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF144B HK3 CFP CARD16 TYMP LYST

2.49e-061938960fbbfcc803edc3cd96b35467ad5cc573af07fd67
ToppCellRV-09._Endothelium_I|World / Chamber and Cluster_Paper

RNF144B VWF HMCN1 ARHGAP31 ARHGAP29 SEC14L1

2.49e-06193896e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCellnucseq-Immune-Immune_Myeloid-pMON-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RNF144B HK3 CFP TYMP LYST SEC14L1

2.57e-06194896e237384b02be460d44eeada3026a5691c66f6fc1
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PROK2 IGF2R HK3 CARD16 TYMP LYST

2.57e-06194896e2d0dfb92356fa7ad7008aa8ac4198e2ac5d2495
ToppCellILEUM-inflamed-(3)_mature_DC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RNF144B NELL2 MTHFR CFP TYMP LYST

2.57e-06194896369bbf4e8e2d674e5a51a614b52b97d05d3ab9c7
ToppCellnucseq-Immune-Immune_Myeloid-pMON|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RNF144B HK3 CFP TYMP LYST SEC14L1

2.57e-061948960bc83ae79873a5e473e6e1e3111924cd003986a1
ToppCellLA-08._Macrophage|World / Chamber and Cluster_Paper

RNF144B DPYD SIGLEC1 TYMP IGSF21 MUC6

2.57e-06194896c1805572bcc11b1cd29083329d7b5911489fb758
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DPYD HK3 CFP SIGLEC1 TYMP LYST

2.57e-06194896885355ebe98e974f841cc59dce3b5228c642c5d0
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MST1 NELL1 PDLIM3 SLIT3 ALDH1A3 CHAC1

2.57e-06194896421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCellRA-08._Macrophage|RA / Chamber and Cluster_Paper

RNF144B DPYD SIGLEC1 TYMP IGSF21 MUC6

2.57e-06194896ac26e5c71d5069622de72fa25a9c920887ac2c19
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B DPYD MIS18BP1 HK3 CFP LYST

2.64e-061958961d58585557bf8e9ce4d514e128d3a902b526331d
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

RNF144B VWF HMCN1 ARHGAP31 ARHGAP29 SEC14L1

2.64e-06195896fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellCOVID-19-Myeloid-Monocyte-derived_macrophages|COVID-19 / group, cell type (main and fine annotations)

RNF144B DPYD MOB3B SIGLEC1 TYMP IGSF21

2.64e-06195896c172c5599379c29123340621a36bfb1fc90c2115
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-cDC2|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF144B SLIT3 AKAP13 CFP TYMP TACSTD2

2.64e-061958969c6bed8414633813e1655bbeaab682fb296958a9
ToppCellLA-08._Macrophage|LA / Chamber and Cluster_Paper

RNF144B DPYD SIGLEC1 TYMP IGSF21 MUC6

2.64e-061958965e1d5bdb8874091f5a2b1d0a8cc9008165718a97
ToppCellLV-09._Endothelium_I|World / Chamber and Cluster_Paper

RNF144B VWF HMCN1 ARHGAP31 ARHGAP29 SEC14L1

2.64e-0619589619e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell10x5'-blood-Myeloid_Monocytic-Nonclassical_monocytes|blood / Manually curated celltypes from each tissue

RNF144B HK3 ARHGAP29 CFP CARD16 TYMP

2.64e-0619589688d65c7c3a28922c125bd9f7c403a55d7d4d83a9
ToppCellcontrol-Non-classical_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNF144B HK3 CFP CARD16 TYMP LYST

2.72e-061968961d71a5be652dd3281aba4f984f6ef84c993c5f63
ToppCell(7)_Macrophage|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

RNF144B NELL1 CFP TYMP IGSF21 ITGB5

2.72e-06196896f1c822860d2a0bae84b0263b0151185756423e0f
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

PROK2 DPYD HK3 CFP SIGLEC1 TYMP

2.81e-06197896a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellCOVID-19-lung-Capillary_1|lung / Disease (COVID-19 only), tissue and cell type

FZD4 RNF144B VWF ARHGAP31 ARHGAP29 SEC14L1

2.81e-061978967e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDLIM3 PDLIM1 SLIT3 CARD16 ALDH1A3 DENND2B

2.81e-06197896236a40eb6c08e1d179cf0fb5450b032975c5f6b6
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_capillary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FZD4 RNF144B VWF PDLIM1 ARHGAP29 SEC14L1

2.81e-0619789681718164c9802ee20c860ffbda7e62d5e9a76f16
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

RNF144B VWF HMCN1 ARHGAP31 ARHGAP29 SEC14L1

2.81e-06197896ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF144B HK3 CFP CARD16 TYMP LYST

2.81e-06197896b4f6501c266328439cba4f174e594a6a04a252a1
ToppCellLV-09._Endothelium_I|LV / Chamber and Cluster_Paper

RNF144B VWF HMCN1 ARHGAP31 ARHGAP29 SEC14L1

2.81e-06197896f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCellnormal-na-Myeloid-non-classical_monocyte-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF144B HK3 CFP CARD16 TYMP LYST

2.89e-06198896d91bd26e499637949768587603cad3c03dcc56e7
ToppCellnormal-na-Myeloid-non-classical_monocyte|normal / PBMC cell types (v2) per disease, treatment status, and sex

RNF144B HK3 CFP CARD16 TYMP LYST

2.89e-06198896f5a12861e2b8ff8309f3e4d0ad83d4f6860cc616
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAF4 FCGBP PDLIM1 DUOX2 ALDH1A3 TACSTD2

2.89e-0619889672d91bd0c727ecadc41e023a16c9326158db1b7b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRAF4 FCGBP PDLIM1 DUOX2 ALDH1A3 TACSTD2

2.89e-06198896441608034c787e55691558a480dcd07e37419138
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FZD4 VWF HMCN1 PDLIM1 ARHGAP29 TNFRSF10D

2.89e-061988967cddd474416651088a4e08edfc0ac420ff10a5fe
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FZD4 VWF HMCN1 PDLIM1 ARHGAP29 AGRN

2.97e-061998960602e2b2aa56d106da63bd342a38bef437b4d496
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FZD4 VWF HMCN1 PDLIM1 ARHGAP29 AGRN

2.97e-06199896463ba77dc4c85eebb343f29a42c7ac889b0497c9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF144B HK3 CFP CARD16 TYMP LYST

2.97e-06199896df946601b295be5419c09befbfa73f4314eef116
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_capillary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FZD4 RNF144B VWF PDLIM1 ARHGAP29 SEC14L1

2.97e-06199896772b3f60b83e29b958e1e70dadfd9f058ed4cb7c
ToppCellParenchymal-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD16|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RNF144B HK3 CFP CARD16 TYMP LYST

3.06e-0620089683d9aa5b46ae7a71a258b2e44b3251f95bc9a1b7
ToppCellBronchial-10x5prime-Immune_Myeloid-Monocytic-Monocyte_CD16|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RNF144B HK3 CFP CARD16 TYMP LYST

3.06e-06200896d39bf03817b76c9dfcbcd868341b51bb8601ea9b
ToppCellCOVID_vent-Myeloid-Monocytic-CD14+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

DPYD HK3 CFP SIGLEC1 TYMP LYST

3.06e-06200896e57452b73abb21cb3f645d45523ab93f6bef0243
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FZD4 RNF144B VWF PDLIM1 ARHGAP29 SEC14L1

3.06e-062008966567683f8f534310fecb44a6721909183fdc15ca
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNF144B FCGBP HK3 LRCH4 AKAP13 TYMP

3.06e-0620089674ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RNF144B HK3 CFP CARD16 TYMP LYST

3.06e-0620089697f261d56bc6c55683eb4c42670d00b9a6992a26
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NELL1 EGF SLIT3 ASTN2 DNAI3

5.26e-06125895b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PROK2 FCGBP LOXHD1 KCNA10

9.97e-0667894e53dfc288c943656a0b064afe593ea2101d75437
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3_(Neuron.Gad1Gad2-Slc17a8.Synpr-Sncg-Yjefn3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

PROK2 FCGBP LOXHD1 KCNA10

9.97e-06678941841cee311a4b1b802c9e872793435afb730592f
ToppCellfacs-Aorta-Heart-3m-Epithelial-epithelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ5 ADGRB2 MASTL IGSF21 BHMT

1.32e-051518950de76acd1b204345dce7f33be2a1ed9fbe9e6da0
ToppCellfacs-Aorta-Heart-3m-Epithelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ5 ADGRB2 MASTL IGSF21 BHMT

1.32e-0515189520b9c8fb966c5d62ff909cc4a4616b109b78cdca
ToppCellfacs-Aorta-Heart-3m-Epithelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNQ5 ADGRB2 MASTL IGSF21 BHMT

1.32e-05151895bee48137d1f5f27a24571a59c835284651d38538
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PROK2 ALDH1A3 ERVW-1 TACSTD2 AGRN

1.74e-0516089558ed3a074932ccc951e07868dfdc61b99ae1cc2b
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROK2 HK3 CFP TACSTD2 LYST

1.80e-05161895e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROK2 HK3 CFP TACSTD2 LYST

1.80e-051618958280a029026c272cae9649b27575831b0dd4e242
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYD HK3 FZD5 SLIT3 SIGLEC1

2.27e-0516989515a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 ANO6 CFP SIGLEC1 ITGB5

2.27e-0516989544d841fd997a6f26104f16cd00223ecce8352f43
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FCGBP PDLIM3 HMCN1 ASTN2 TACSTD2

2.27e-05169895d2def7229fe9d6b0c70cfed349ede491c8c137a0
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 ANO6 CFP SIGLEC1 ITGB5

2.27e-051698950f5e737b265ba333275a0cd289dab029a1542075
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 ANO6 CFP SIGLEC1 ITGB5

2.27e-05169895aec1b4c7e973a31c53aaea47c2c05d24ce16aa4f
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Monocytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PROK2 LOXHD1 HK3 CFP TYMP

2.33e-051708951c3c03821c90d41de92fef3278f71093a7fd709c
ToppCelldroplet-Kidney-nan-21m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDLIM1 DUOX2 CFP SLURP2 IGSF21

2.33e-0517089553fd50c9a27d47662fbcbd7e9e9837f72ac448c5
ToppCellwk_08-11-Hematologic-Meg-ery-Megakaryocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CATIP LOXHD1 EGF MFSD2B MAP3K5

2.40e-051718959dda25df493766723335851b3c3d89735b6e8051
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

KCNQ5 ARHGAP31 AKAP13 CFP ACTR3B

2.40e-051718950d14bc9688c427ba2265984987dc3eea195b19eb
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP29 ALDH1A3 TACSTD2 AGRN MUC6

2.47e-051728950be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 ANO6 CFP SIGLEC1 ITGB5

2.61e-051748953533a47885af453d97739e5576e989d93d31be32
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 NELL2 SLIT3 GRM1 IGSF21

2.61e-05174895bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 ANO6 CFP SIGLEC1 ITGB5

2.61e-05174895dc4298c1d9359f7e37454e9451f889017227d5cf
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 ANO6 CFP SIGLEC1 ITGB5

2.61e-05174895b487c5c46f074a69b9526a2c72daf218f66aa44b
ToppCellwk_20-22-Hematologic-Myeloid-Promonocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HK3 CFP ERVW-1 TYMP LYST

2.68e-05175895654299df246debe0a5b12f0d9568eb828bb94bb9
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-erythroid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MST1 EGFR MYT1 SIGLEC1 MUC6

2.83e-05177895b647667da62a91dbe3890820142626e26aa779d2
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 DPYD AKAP13 GRM1 IGSF21

2.91e-05178895b169aa5eaa51730daaec69c6bc58126be1592a50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NELL1 EGF HMCN1 ASTN2 GRM1

2.91e-051788954df6218b20c2f076c22346d23260964cc0d73e65
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF EGF PDLIM3 ARHGAP29 ACTR3B

2.99e-05179895a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 DPYD SLIT3 AKAP13 GRM1

2.99e-05179895747a32460b257fffca30527b56a74720eb9c12e4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NELL1 NELL2 SLIT3 GRM1 IGSF21

2.99e-05179895065a50952e8703fa07767beb6b73a090bf378ca6
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

HK3 SIGLEC1 TYMP IGSF21 ITGB5

3.07e-051808957be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCellmetastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Brain / Location, Cell class and cell subclass

FCGBP MOB3B CARD16 TACSTD2 CBR3

3.07e-0518089551727cb66fe7a7709453f7026e0ff3d6c93d5aa5
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

FZD4 ARHGAP31 ARHGAP29 DENND2B SEC14L1

3.07e-05180895b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD207+CD1a+_LCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

FCGBP SLIT3 MOB3B TACSTD2 CBR3

3.07e-05180895289f8c4b53ffd164fee1f459a9315c0deb5f76d0
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(other)|COVID-19 / group, cell type (main and fine annotations)

FZD4 VWF PDLIM1 ARHGAP29 SEC14L1

3.15e-0518189526eb4ee57a70dbf54e096b73129fda9dfda1f6ec
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B EGFR SLIT3 ARHGAP29 ASTN2

3.15e-05181895071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 ANO6 CFP SIGLEC1 ITGB5

3.15e-05181895a93df1ba23d5b5f249491d69d12bfc0e274dafcf
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Dendritic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFP CARD16 SIGLEC1 TYMP ITGB5

3.23e-051828959a68d3bd1cc9139de9e9e711c249d47ade826bb1
Drugketopantoate

DPYD EGFR TYMP LYST

4.19e-0629864CID000000038
Drugstrontium phosphate

VWF EGF SMCP

1.12e-0512863CID000159737
Drug5-ethylbarbituric acid

EGF EGFR

1.41e-052862CID000017292
Drug5-phenylbarbituric acid

EGF EGFR

1.41e-052862CID000089646
DrugVinca-type compound

EGF EGFR

1.41e-052862CID000494342
DrugPD173952

VWF EGF EGFR

2.29e-0515863CID005328733
Drug5-aza-2'-deoxycytidine

NELL1 FCGBP EGFR NANOG SLIT3 LRCH4 ARHGAP29 DUOX2 TNFRSF10D PMEL ALDH1A3

2.79e-056388611CID000016886
Drugpanobinostat

PROK2 RNF144B NELL1 NELL2 EGF PDLIM1 ARHGAP31 FZD5 NANOG SLIT3 ASTN2 ALDH1A3 TACSTD2 IGSF21 ITGB5 CHAC1

3.44e-0513338616ctd:C496932
DrugCamptothecin

RAD51C DPYD LRCH4 AKAP13 AGRN MAP3K5

3.60e-05163866ctd:D002166
DrugAluminum Silicates

EGF EGFR

4.22e-053862ctd:D000538
DrugFD137 nitrosourea

EGF EGFR

4.22e-053862ctd:C471268
DrugPtpc

HK3 CARD16 TNFRSF10D MAP3K5

5.59e-0555864CID003036276
DrugZD4190

NELL1 NELL2 EGF

5.66e-0520863CID005329032
Drug5-fluoropyrimidine

DPYD MTHFR TYMP

5.66e-0520863CID000069605
DrugPTK/ZK

VWF EGF EGFR PMEL

6.00e-0556864CID000151193
DrugProscillaridin A [466-06-8]; Down 200; 7.6uM; MCF7; HT_HG-U133A

ASTN2 TRMT1L CBR3 CHAC1 RBCK1 MAP3K5

6.06e-051798664404_DN
Druggemcitabine

DPYD VWF EGF EGFR NANOG ALDH1A3 TYMP

7.38e-05270867ctd:C056507
DrugEGFR/ErbB2 inhibitor

VWF EGFR

8.42e-054862CID009843206
DrugAC1NR2YL

EGF EGFR

8.42e-054862CID005283757
DrugAC1NBIRU

IGF2R CARD16 SIGLEC1 TNFRSF10D

8.96e-0562864CID004468718
DrugH-89, Dihydrochloride; Up 200; 0.5uM; PC3; HT_HG-U133A

DPYD TRAF4 IGF2R EGF AKAP13 SEC14L1

9.46e-051948666921_UP
DrugNocodazole

EGF NANOG MYT1 TYMP

9.54e-0563864ctd:D015739
DrugAntipyrine [60-80-0]; Down 200; 21.2uM; PC3; HT_HG-U133A

RAD51B EGFR ADGRB2 ASTN2 CHAC1 MAP3K5

9.73e-051958664251_DN
DrugCarbamazepine [298-46-4]; Down 200; 17uM; PC3; HT_HG-U133A

TRAF4 EGFR ADGRB2 AKAP13 GRM1 ITGB5

9.73e-051958665093_DN
DrugAC1NQAB4

PROK2 IGF2R SIGLEC1

9.94e-0524863CID005192841
DrugEpivincamine [6835-99-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A

ASTN2 AKAP13 RNF41 LYST DENND2B CHAC1

1.00e-041968662775_DN
DrugTenoxicam [59804-37-4]; Down 200; 11.8uM; HL60; HT_HG-U133A

ALMS1 PDLIM1 MTHFR GRM1 CBR3 ITGB5

1.03e-041978662501_DN
Drugwortmannin from Penicillium funiculosum; Up 200; 0.01uM; HL60; HT_HG-U133A

NELL2 MTHFR MYT1 TNFRSF10D GRM1 MUC6

1.03e-041978662703_UP
DrugSeneciphylline [480-81-9]; Up 200; 12uM; HL60; HT_HG-U133A

FZD4 RAD51B ALMS1 TNFRSF10D ZNF442 ITGB5

1.03e-041978662140_UP
DrugNaftopidil dihydrochloride [57149-08-3]; Down 200; 8.6uM; PC3; HT_HG-U133A

TRAF4 MTHFR WDR18 ASTN2 ZNF442 AGRN

1.06e-041988664193_DN
DrugNomegestrol acetate [58652-20-3]; Down 200; 10.8uM; PC3; HT_HG-U133A

EGF ASTN2 AKAP13 RNF41 AGRN ITGB5

1.06e-041988666362_DN
DrugClonidine hydrochloride [4205-91-8]; Down 200; 15uM; MCF7; HT_HG-U133A

RAD51B MTHFR DENND2B ITGB5 CHAC1 MAP3K5

1.09e-041998666814_DN
DrugMoroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; HL60; HG-U133A

FZD4 NELL2 TRAF4 MYT1 MOB3B CHAC1

1.09e-041998662027_UP
DrugDocetaxel trihydrate

DPYD EGF EGFR TYMP ITGB5 MAP3K5

1.18e-04202866CID000003143
DrugRG 14921

EGF EGFR

1.40e-045862CID000197517
DrugD 247

EGF EGFR

1.40e-045862CID003048156
Drug6-quinolinecarbaldehyde

EGF EGFR

1.40e-045862CID000765653
DrugTAK-165

EGF EGFR

1.40e-045862CID006444692
DrugThymine

DPYD TYMP

1.40e-045862ctd:D013941
Drugnetivudine

DPYD TYMP

1.40e-045862CID000055281
Drug4-(3-chloroanilino)quinazoline

EGF EGFR

1.40e-045862CID000128872
DrugAC1O3M08

DPYD TYMP

1.40e-045862CID006331955
DrugNSC-33145

DPYD CARD16 TYMP

1.43e-0427863CID000233979
DiseaseColorectal Carcinoma

FZD4 NELL1 DPYD HK3 KCNQ5 KCNA10 EGFR MTHFR GRM1 TYMP ZNF442 IGSF21

9.17e-077028612C0009402
DiseaseUnipolar Depression

PROK2 NELL1 EGF EGFR MTHFR SLIT3 RNF41 GRM1

9.30e-07259868C0041696
DiseaseLeukoencephalopathy

DPYD MTHFR TYMP

3.88e-0611863C0270612
DiseaseMajor Depressive Disorder

PROK2 NELL1 EGF EGFR MTHFR SLIT3 RNF41

7.28e-06243867C1269683
DiseaseMalignant neoplasm of breast

RAD51C RAD51B MST1 DPYD VWF HK3 EGF EGFR MTHFR ARHGAP29 ACCS ASTN2 CFP

1.36e-0510748613C0006142
Diseaseinflammatory bowel disease (is_implicated_in)

EGFR MTHFR ANO6

2.24e-0519863DOID:0050589 (is_implicated_in)
DiseaseHereditary Diffuse Gastric Cancer

DPYD FCGBP EGFR MTHFR ALDH1A3 TYMP MUC6

2.44e-05293867C1708349
DiseaseStomach Neoplasms

DPYD FCGBP EGFR MTHFR ALDH1A3 TYMP MUC6

2.66e-05297867C0038356
DiseaseMalignant neoplasm of stomach

DPYD FCGBP EGFR MTHFR ALDH1A3 TYMP MUC6

2.83e-05300867C0024623
DiseaseNeoplasm Metastasis

MST1 DPYD EGF EGFR MTHFR TYMP

4.25e-05217866C0027627
DiseaseAlcoholic Intoxication, Chronic

VWF EGF EGFR MTHFR GRM1 BHMT

1.36e-04268866C0001973
Diseasegallbladder cancer (is_marker_for)

DPYD EGF

1.75e-047862DOID:3121 (is_marker_for)
Diseaseschizophrenia (is_marker_for)

VWF EGF EGFR

2.90e-0444863DOID:5419 (is_marker_for)
Diseasepancreatic cancer (is_implicated_in)

DPYD EGFR MTHFR TYMP

3.29e-04112864DOID:1793 (is_implicated_in)
Diseasecolon cancer (implicated_via_orthology)

NANOGP8 NANOG

4.54e-0411862DOID:219 (implicated_via_orthology)
DiseaseChildhood Ataxia with Central Nervous System Hypomyelinization

DPYD MTHFR

7.47e-0414862C1858991
Diseasenephroblastoma (is_implicated_in)

IGF2R MTHFR

7.47e-0414862DOID:2154 (is_implicated_in)
DiseaseBladder Neoplasm

EGFR MTHFR TYMP IGSF21

7.63e-04140864C0005695
DiseaseMalignant neoplasm of urinary bladder

EGFR MTHFR TYMP IGSF21

7.83e-04141864C0005684
Diseaseamino acid measurement

NELL2 VWF ALMS1 MYT1 SLIT3 LRCH4 ASTN2 GRM1

8.19e-04678868EFO_0005134
Diseaseglycerate measurement

HMCN1 AGRN

8.60e-0415862EFO_0021029
DiseaseMammary Carcinoma, Human

RAD51C RAD51B MST1 DPYD EGF EGFR MTHFR

8.68e-04525867C4704874
DiseaseMammary Neoplasms, Human

RAD51C RAD51B MST1 DPYD EGF EGFR MTHFR

8.68e-04525867C1257931
DiseaseMammary Neoplasms

RAD51C RAD51B MST1 DPYD EGF EGFR MTHFR

8.87e-04527867C1458155
DiseaseDermatitis

EGF EGFR

9.81e-0416862C0011603
DiseaseBreast Carcinoma

RAD51C RAD51B MST1 DPYD EGF EGFR MTHFR

1.00e-03538867C0678222
DiseaseColonic Neoplasms

DPYD EGFR MTHFR TYMP

1.04e-03152864C0009375
DiseaseMalignant tumor of colon

DPYD EGFR MTHFR TYMP

1.22e-03159864C0007102
DiseaseEndometrial Carcinoma

RNF144B EGFR MTHFR

1.23e-0372863C0476089
DiseaseCongenital hernia of foramen of Morgagni

IGF2R KCNQ5

1.39e-0319862C0265699
DiseaseCongenital hernia of foramen of Bochdalek

IGF2R KCNQ5

1.39e-0319862C0265700
Diseaseankylosing spondylitis (is_implicated_in)

MTHFR ANO6

1.39e-0319862DOID:7147 (is_implicated_in)
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

VWF EGFR

1.39e-0319862DOID:9744 (biomarker_via_orthology)
DiseaseCongenital diaphragmatic hernia

IGF2R KCNQ5

1.70e-0321862C0235833
DiseaseLymphoma, Diffuse

MTHFR BHMT

1.70e-0321862C3714542
DiseaseLow Grade Lymphoma (neoplasm)

MTHFR BHMT

1.70e-0321862C0079747
DiseaseLymphoma, Intermediate-Grade

MTHFR BHMT

1.70e-0321862C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

MTHFR BHMT

1.70e-0321862C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

MTHFR BHMT

1.70e-0321862C0079757
DiseaseNeutropenia

DPYD MTHFR

1.70e-0321862C0027947
DiseaseLymphoma, Undifferentiated

MTHFR BHMT

1.70e-0321862C0024306
DiseaseReticulosarcoma

MTHFR BHMT

1.70e-0321862C0024302
DiseaseLymphoma, Mixed-Cell

MTHFR BHMT

1.70e-0321862C0024304
DiseaseCleft Palate

FZD4 EGF ARHGAP29

1.73e-0381863C0008925
DiseaseLymphoma, Non-Hodgkin, Familial

MTHFR BHMT

1.87e-0322862C4721532
Diseasetransitional cell carcinoma (is_implicated_in)

MTHFR TYMP

1.87e-0322862DOID:2671 (is_implicated_in)
DiseaseLymphoma, Small Noncleaved-Cell

MTHFR BHMT

1.87e-0322862C0079770
DiseaseParkinson Disease

IGF2R MTHFR MAP3K5

1.99e-0385863C0030567
DiseaseCancer of Head

DPYD EGFR

2.22e-0324862C0751177
DiseaseHead Neoplasms

DPYD EGFR

2.22e-0324862C0018675
DiseaseUpper Aerodigestive Tract Neoplasms

DPYD EGFR

2.22e-0324862C0887900
Diseasemigraine disorder, diastolic blood pressure

ASTN2 ITGB5

2.41e-0325862EFO_0006336, MONDO_0005277
DiseaseNeck Neoplasms

DPYD EGFR

2.41e-0325862C0027533
DiseaseCancer of Neck

DPYD EGFR

2.41e-0325862C0746787
Diseasecoronary artery disease

NELL1 DPYD IGF2R MTHFR DUOX2 ASTN2 AKAP13 DENND2B ITGB5 TLCD5

2.47e-0311948610EFO_0001645
Diseasedihomo-gamma-linolenic acid measurement

NANOGP8 ANO6

2.81e-0327862EFO_0007763
Diseasethrombocytopenia (is_implicated_in)

MTHFR MASTL

2.81e-0327862DOID:1588 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
SPSVPLVIGCAVSCM

ADGRB2

931

O60241
ASGKPVAATMCIGPE

BHMT

176

Q93088
PPLCIAQCGGTVEEM

CSMD2

1961

Q7Z408
APTTCLGPTCMQDLG

ACCS

11

Q96QU6
MAGSLPPCVVDCGTG

ACTR3B

1

Q9P1U1
CLETVASNPGMPVKC

MASTL

271

Q96GX5
QMTGLCSCKPGVAGP

AGRN

861

O00468
SIPVVGPISCSQCMK

AKAP13

1796

Q12802
QSPRGMGCKPEAVCS

ALMS1

2561

Q8TCU4
CCGNTMVLKPAEQTP

ALDH1A3

196

P47895
PLGLTCGMVCPTSDL

DPYD

121

Q12882
KNLIGTFACVCPPGM

FBN3

2226

Q75N90
EGVMTGPLLQSCCAP

DNAI3

701

Q8IWG1
SMIDIVCCPTPFLVG

DENND2B

936

P78524
SSGCVCPEELKPMKD

ASTN2

676

O75129
ITGPPGCGKTQFCIM

RAD51B

106

O15315
PLMKTTEICGAPGVG

RAD51C

116

O43502
CRKMGVPEADLCSPS

LRCH4

611

O75427
FCTERTCPVMSGGPK

MOB3B

81

Q86TA1
REGCGSPITCPDMVC

RNF144B

66

Q7Z419
VCHPDIGGKIIMCPQ

ANO6

336

Q4KMQ2
APTCQMLATGVACVP

MUC6

786

Q6W4X9
MLATGVACVPTKCEP

MUC6

791

Q6W4X9
KACTDMGITCPIVPG

MTHFR

241

P42898
CCGLETKPEVSPLNM

SMCP

71

P49901
VPGETGLPGSMKDTC

MIS18BP1

326

Q6P0N0
CDCPGLVMPSFVSTK

LSG1

436

Q9H089
MKLVESSGCPALDCP

NELL2

366

Q99435
MPCLAPIAAKVGSVG

MGA

3011

Q8IWI9
GCTFINKPTRPGCEM

RBCK1

201

Q9BYM8
GGETLLSVCPMVPKD

KCNQ5

811

Q9NR82
VDAPSLGKCMTFPCG

LOXHD1

1056

Q8IVV2
SCGPPGMTKNVEKAC

DUOX2

1516

Q9NRD8
ASDCKESSPMPVICG

NANOG

16

Q9H9S0
AGLCILMVGSTPKTP

MFSD2B

471

A6NFX1
VSPCPVTCGLGQTME

CFP

266

P27918
VLPVGTMPEGTIVCC

RPL8

101

P62917
TMPEGTIVCCLEEKP

RPL8

106

P62917
TMMGCEPGVRPCEVG

HK3

226

P52790
TEPGAFGEMCEKCPT

ITGB5

616

P18084
CRGGVLVKITEMCPP

NELL1

356

Q92832
GDITVMECKTSGIPP

HMCN1

716

Q96RW7
GDKMCPGCSDPVQRI

CBLL1

141

Q75N03
RICTPMGKLGDSCHP

PROK2

56

Q9HC23
DMCPTTPGGKIVGTL

KCNA10

426

Q16322
MCSIGVVDQGCFPKP

ARHGAP29

896

Q52LW3
CTEKINIPIGPCGGM

FZD4

106

Q9ULV1
NIPIGPCGGMCLSVK

FZD4

111

Q9ULV1
PVCQEITVPMCRGIG

FZD5

31

Q13467
IDGPHCVKTCPAGVM

EGFR

586

P00533
FTLVCIVSGGKPAPM

IGSF21

166

Q96ID5
MGVPVCPPASSKCIN

EGF

876

P01133
VLSPVEPSCEGMQCA

FCGBP

436

Q9Y6R7
IVDAVGTMLPCFCPT

CHAC1

201

Q9BUX1
GSPGCCIITKMPILR

CATIP

261

Q7Z7H3
GICCCMDPKSVIIPL

LYST

581

Q99698
CCPGPVKTDMDGKDS

CBR3

226

O75828
PVAKMVCGPSGSQLV

MST1

556

P26927
PTGMDCKLVGPETLC

FAM221A

61

A4D161
LCPGHVGLCDAMKPI

GRM1

431

Q13255
KRPVTCEQGCGLEMP

RNF41

111

Q9H4P4
CMCEVPEGGLVPKSL

SEC14L1

491

Q92503
MALPPGTTGVKDCVF

SPACA4

11

Q8TDM5
AMPTCSSPEGRIKLC

CARD16

101

Q5EG05
MGSLEKAGPVSPGCV

PARP10

421

Q53GL7
KLPMCDKCGTGIVGV

PDLIM1

256

O00151
SLGCTIIEMATGKPP

MAP3K5

866

Q99683
GTMPVCGTILGKPAS

IGF2R

971

P11717
MHGVPCPAGAAVCKV

IGF2R

1701

P11717
MINPSCPGGLGVTVC

ERVW-1

91

Q9UQF0
LPCNCHGSMPGKTAI

TRMT1L

511

Q7Z2T5
SGPVVQTMYKACPCG

TGIF2LY

146

Q8IUE0
CPTNKMTVCSPDGPG

TACSTD2

36

P09758
LPSKCIPMICAGHEE

IQCA1L

386

A6NCM1
ESDCKESSPMPVICG

NANOGP8

16

Q6NSW7
MPLCDKCGSGIVGAV

PDLIM3

291

Q53GG5
KIMCPGPVTCLTASP

WDR18

76

Q9BV38
PKEACMEISSPGCQP

PMEL

521

P40967
KMCHIGCPDIPSLGL

SLURP2

66

P0DP57
GCPRGMVKVSNCTPR

TNFRSF10D

161

Q9UBN6
SKVPIMECRGGCGPQ

SLIT3

1471

O75094
GGPTCSVIAHMCPEI

UGDH

16

O60701
GACLLFCEMVSPTPK

TLCD5

176

Q6ZRR5
SMGCVSGCLCPPGMV

VWF

801

P04275
CLAEGGKIMKIPGTC

VWF

2701

P04275
MVGILPLCCSGCVPS

KRT10-AS1

1

Q8N816
KSSPVDATAPCMCEG

ARHGAP31

1271

Q2M1Z3
CGGCSPRMKVTKAPN

SIGLEC1

656

Q9BZZ2
CGKPMREPVQVSTCG

TRAF4

21

Q9BUZ4
SGFSMPGKPGVVCVE

RWDD2B

216

P57060
ELGSKVPFCPMVGSE

RUVBL1

86

Q9Y265
PGVDPCKSSVCGEIM

ZNF442

111

Q9H7R0
PALAACGCKVPMISG

TYMP

131

P19971
MKCPVPGCVGLGHIS

MYT1

891

Q01538