Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD2 KMT2A TAF1 TAF1L	3.15e-06	30	68	4	GO:0070577
GeneOntologyMolecularFunction	histone binding	SCML2 ZCWPW1 BRD2 GLYR1 KMT2A CHD4 TAF1 TAF1L	3.22e-06	265	68	8	GO:0042393
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD2 KMT2A TAF1 TAF1L	3.61e-06	31	68	4	GO:0140033
GeneOntologyMolecularFunction	modification-dependent protein binding	ZCWPW1 BRD2 GLYR1 KMT2A TAF1 TAF1L	7.20e-05	206	68	6	GO:0140030
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	1.14e-04	5	68	2	GO:0061628
GeneOntologyMolecularFunction	chromatin binding	SCML2 ERCC6 BRD2 NELFA GLYR1 KMT2A CHD4 TAF1 TAF1L CIC	1.89e-04	739	68	10	GO:0003682
GeneOntologyMolecularFunction	methylated histone binding	ZCWPW1 GLYR1 TAF1 TAF1L	2.12e-04	86	68	4	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	ZCWPW1 GLYR1 TAF1 TAF1L	2.31e-04	88	68	4	GO:0140034
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	4.05e-04	9	68	2	GO:0001181
GeneOntologyMolecularFunction	actin binding	FLNA FLNB COBL PRKCE PSG8 LIMCH1 FMNL1	1.20e-03	479	68	7	GO:0003779
GeneOntologyCellularComponent	actin cytoskeleton	FLNA FLNB SH3PXD2B CAPN2 COBL LIMCH1 ADAM8 FYB1 ZYX	7.86e-05	576	66	9	GO:0015629
GeneOntologyCellularComponent	nuclear protein-containing complex	FLNA SCML2 ERCC6 WDR33 NELFA UTP4 KMT2A CHD4 TAF1 TAF1L SLX4 INO80B LARP7 HMG20B	8.23e-05	1377	66	14	GO:0140513
GeneOntologyCellularComponent	MLL1 complex	KMT2A TAF1 TAF1L	1.40e-04	32	66	3	GO:0071339
GeneOntologyCellularComponent	MLL1/2 complex	KMT2A TAF1 TAF1L	1.53e-04	33	66	3	GO:0044665
GeneOntologyCellularComponent	actin filament bundle	FLNA FLNB LIMCH1 ZYX	5.31e-04	118	66	4	GO:0032432
HumanPheno	Accessory carpal bones	FLNA FLNB	1.78e-05	2	22	2	HP:0004232
HumanPheno	Bipartite calcaneus	FLNA FLNB	1.78e-05	2	22	2	HP:0008127
HumanPheno	Prominent forehead	SCYL2 FLNA FLNB SH3PXD2B KMT2A TAF1 LARP7	7.51e-05	261	22	7	HP:0011220
HumanPheno	Localized skin lesion	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA BMS1 ANKRD11 KMT2A APOB TAF1 SLX4	9.46e-05	897	22	12	HP:0011355
HumanPheno	Abnormal cardiac atrium morphology	FLNA FLNB SH3PXD2B NELFA KMT2A CHD4 DNAAF11 ATP2B1 SLX4 LARP7	1.05e-04	617	22	10	HP:0005120
HumanPheno	Anterior concavity of thoracic vertebrae	FLNA SH3PXD2B	1.06e-04	4	22	2	HP:0004611
HumanPheno	Abnormal foramen magnum morphology	FLNA FLNB CHD4	1.17e-04	23	22	3	HP:0002699
HumanPheno	Abnormal nasal tip morphology	SCYL2 FLNA FLNB SH3PXD2B KMT2A TAF1 SLX4 NUAK2	1.25e-04	386	22	8	HP:0000436
HumanPheno	Short palpebral fissure	KMT2A CHD4 SLX4 LARP7 NUAK2	1.38e-04	122	22	5	HP:0012745
HumanPheno	Abnormal hip bone morphology	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 CHD4 TAF1 SLX4	1.70e-04	653	22	10	HP:0003272
HumanPheno	Abnormal size of the palpebral fissures	ERCC6 ANKRD11 KMT2A CHD4 SLX4 LARP7 NUAK2	1.74e-04	298	22	7	HP:0200007
HumanPheno	Scoliosis	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A TAF1 ATP2B1 CIC SLX4 LARP7	1.78e-04	1122	22	13	HP:0002650
HumanPheno	Depressed nasal tip	FLNA KMT2A TAF1	2.14e-04	28	22	3	HP:0000437
HumanPheno	Atrial septal defect	FLNA FLNB SH3PXD2B NELFA KMT2A CHD4 ATP2B1 SLX4 LARP7	2.24e-04	541	22	9	HP:0001631
HumanPheno	Abnormality of the atrial septum	FLNA FLNB SH3PXD2B NELFA KMT2A CHD4 ATP2B1 SLX4 LARP7	2.24e-04	541	22	9	HP:0001630
HumanPheno	Abnormal atrial septum morphology	FLNA FLNB SH3PXD2B NELFA KMT2A CHD4 ATP2B1 SLX4 LARP7	2.34e-04	544	22	9	HP:0011994
HumanPheno	Vertebral fusion	FLNA FLNB ANKRD11 CHD4	2.46e-04	74	22	4	HP:0002948
HumanPheno	Spondylolysis	FLNA FLNB	2.64e-04	6	22	2	HP:0003304
HumanPheno	Prominent coccyx	SH3PXD2B TAF1	2.64e-04	6	22	2	HP:0040016
HumanPheno	Pectus excavatum	FLNA FLNB SH3PXD2B KMT2A NHLRC2 TAF1 ATP2B1	2.87e-04	323	22	7	HP:0000767
HumanPheno	Fused cervical vertebrae	FLNA FLNB CHD4	4.19e-04	35	22	3	HP:0002949
HumanPheno	Abnormality of the palpebral fissures	FLNA SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A CHD4 TAF1 SLX4 LARP7 NUAK2	4.25e-04	880	22	11	HP:0008050
HumanPheno	Abnormal curvature of the vertebral column	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A TAF1 ATP2B1 CIC SLX4 LARP7	4.31e-04	1219	22	13	HP:0010674
HumanPheno	Abnormal pelvic girdle bone morphology	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 CHD4 TAF1 SLX4	4.33e-04	730	22	10	HP:0002644
HumanPheno	Abnormal morphology of the great vessels	FLNA FLNB SH3PXD2B ERCC6 KMT2A APOB CHD4 DNAAF11 ATP2B1 SLX4	4.64e-04	736	22	10	HP:0030962
HumanPheno	Broad phalanges of the thumb	FLNA FLNB	4.91e-04	8	22	2	HP:0009651
HumanPheno	Vertebral segmentation defect	FLNA FLNB ANKRD11 CHD4 TAF1	5.19e-04	162	22	5	HP:0003422
HumanPheno	Abnormal calvaria morphology	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA BMS1 ANKRD11 KMT2A CHD4 TAF1 ATP2B1 SLX4	5.80e-04	1254	22	13	HP:0002683
HumanPheno	Abnormal sacrum morphology	FLNB SH3PXD2B NELFA KMT2A TAF1	5.97e-04	167	22	5	HP:0005107
HumanPheno	Long toe	FLNA NELFA KMT2A ATP2B1 CIC	6.14e-04	168	22	5	HP:0010511
HumanPheno	Abnormal coccyx morphology	SH3PXD2B TAF1	6.29e-04	9	22	2	HP:0008519
HumanPheno	Abnormal hip joint morphology	SCYL2 FLNA FLNB SH3PXD2B ANKRD11 CHD4 TAF1 SLX4	6.55e-04	490	22	8	HP:0001384
HumanPheno	Functional abnormality of male internal genitalia	SCYL2 FSIP2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A CHD4 DNAAF11 SLX4 LARP7	6.57e-04	1269	22	13	HP:0000025
HumanPheno	Aplasia cutis congenita	NELFA BMS1 TAF1	6.70e-04	41	22	3	HP:0001057
HumanPheno	Abnormal synovial membrane morphology	SCYL2 FLNA FLNB SH3PXD2B ANKRD11 CHD4 TAF1 SLX4	7.81e-04	503	22	8	HP:0005262
HumanPheno	Abnormal cardiac septum morphology	FLNA FLNB SH3PXD2B NELFA ANKRD11 KMT2A CHD4 ATP2B1 SLX4 LARP7	8.04e-04	787	22	10	HP:0001671
HumanPheno	Abnormal location of ears	SCYL2 FLNA FLNB SH3PXD2B NELFA ANKRD11 KMT2A CHD4 TAF1 ATP2B1 LARP7	8.04e-04	945	22	11	HP:0000357
HumanPheno	Abnormal pinna morphology	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A CHD4 TAF1 ATP2B1 SLX4 LARP7	8.37e-04	1299	22	13	HP:0000377
HumanPheno	Abnormality of globe location	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A CHD4 TAF1 SLX4 LARP7	8.61e-04	1122	22	12	HP:0100886
HumanPheno	Abnormal male reproductive system physiology	SCYL2 FSIP2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A CHD4 DNAAF11 SLX4 LARP7	9.42e-04	1314	22	13	HP:0012874
HumanPheno	Delayed eruption of teeth	FLNA FLNB SH3PXD2B ERCC6 NELFA	9.52e-04	185	22	5	HP:0000684
HumanPheno	Abnormality of calvarial morphology	SCYL2 FLNA FLNB SH3PXD2B NELFA BMS1 ANKRD11 KMT2A CHD4 TAF1 ATP2B1 SLX4	9.53e-04	1134	22	12	HP:0002648
HumanPheno	Fibular aplasia	FLNA FLNB	9.57e-04	11	22	2	HP:0002990
HumanPheno	Anterior bulging of the globe	FLNA FLNB SH3PXD2B NELFA TAF1 SLX4	9.76e-04	283	22	6	HP:0000644
HumanPheno	Proptosis	FLNA FLNB SH3PXD2B NELFA TAF1 SLX4	9.76e-04	283	22	6	HP:0000520
HumanPheno	Abnormal aortic morphology	FLNA FLNB ERCC6 APOB CHD4 ATP2B1 SLX4	1.07e-03	401	22	7	HP:0001679
HumanPheno	Abnormality of the outer ear	SCYL2 FLNA FLNB SH3PXD2B ERCC6 NELFA ANKRD11 KMT2A CHD4 TAF1 ATP2B1 SLX4 LARP7	1.12e-03	1337	22	13	HP:0000356
HumanPheno	Abnormality of the capitate bone	FLNA FLNB	1.14e-03	12	22	2	HP:0004262
HumanPheno	Abnormality of the hamate bone	FLNA FLNB	1.14e-03	12	22	2	HP:0004259
HumanPheno	Capitate-hamate fusion	FLNA FLNB	1.14e-03	12	22	2	HP:0001241
HumanPheno	Small foramen magnum	FLNB CHD4	1.14e-03	12	22	2	HP:0002677
Domain	TAF_II_230-bd	TAF1 TAF1L	1.35e-05	2	69	2	IPR009067
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	1.35e-05	2	69	2	IPR022591
Domain	-	TAF1 TAF1L	1.35e-05	2	69	2	1.10.1100.10
Domain	TBP-binding	TAF1 TAF1L	1.35e-05	2	69	2	PF09247
Domain	DUF3591	TAF1 TAF1L	1.35e-05	2	69	2	PF12157
Domain	TAF1_animal	TAF1 TAF1L	1.35e-05	2	69	2	IPR011177
Domain	BROMODOMAIN_2	BRD2 KMT2A TAF1 TAF1L	1.56e-05	41	69	4	PS50014
Domain	BROMO	BRD2 KMT2A TAF1 TAF1L	1.72e-05	42	69	4	SM00297
Domain	Bromodomain	BRD2 KMT2A TAF1 TAF1L	1.72e-05	42	69	4	IPR001487
Domain	-	BRD2 KMT2A TAF1 TAF1L	1.72e-05	42	69	4	1.20.920.10
Domain	hSH3	PRAM1 FYB1	4.03e-05	3	69	2	IPR029294
Domain	hSH3	PRAM1 FYB1	4.03e-05	3	69	2	PF14603
Domain	Bromodomain_CS	BRD2 TAF1 TAF1L	1.18e-04	26	69	3	IPR018359
Domain	AT_hook	PRR12 GLYR1 KMT2A	1.32e-04	27	69	3	SM00384
Domain	AT_hook_DNA-bd_motif	PRR12 GLYR1 KMT2A	1.32e-04	27	69	3	IPR017956
Domain	BROMODOMAIN_1	BRD2 TAF1 TAF1L	3.43e-04	37	69	3	PS00633
Domain	Bromodomain	BRD2 TAF1 TAF1L	3.71e-04	38	69	3	PF00439
Domain	IG_FLMN	FLNA FLNB	5.94e-04	10	69	2	SM00557
Domain	Filamin	FLNA FLNB	7.24e-04	11	69	2	PF00630
Domain	FILAMIN_REPEAT	FLNA FLNB	7.24e-04	11	69	2	PS50194
Domain	Filamin/ABP280_rpt	FLNA FLNB	7.24e-04	11	69	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNA FLNB	7.24e-04	11	69	2	IPR017868
Domain	HMG_BOX_2	TAF1 CIC HMG20B	1.05e-03	54	69	3	PS50118
Domain	AT_hook	PRR12 KMT2A	1.56e-03	16	69	2	PF02178
Domain	HMG_box_dom	CHD4 CIC HMG20B	1.79e-03	65	69	3	IPR009071
Domain	CH	FLNA FLNB LIMCH1	1.79e-03	65	69	3	SM00033
Domain	CH	FLNA FLNB LIMCH1	2.21e-03	70	69	3	PF00307
Domain	-	FLNA FLNB LIMCH1	2.30e-03	71	69	3	1.10.418.10
Domain	PWWP	ZCWPW1 GLYR1	2.45e-03	20	69	2	SM00293
Domain	CH	FLNA FLNB LIMCH1	2.49e-03	73	69	3	PS50021
Domain	CH-domain	FLNA FLNB LIMCH1	2.69e-03	75	69	3	IPR001715
Domain	Actinin_actin-bd_CS	FLNA FLNB	3.24e-03	23	69	2	IPR001589
Domain	PWWP	ZCWPW1 GLYR1	3.24e-03	23	69	2	PF00855
Domain	PWWP_dom	ZCWPW1 GLYR1	3.24e-03	23	69	2	IPR000313
Domain	ACTININ_2	FLNA FLNB	3.24e-03	23	69	2	PS00020
Domain	ACTININ_1	FLNA FLNB	3.24e-03	23	69	2	PS00019
Domain	PWWP	ZCWPW1 GLYR1	3.52e-03	24	69	2	PS50812
Domain	SNF2_N	ERCC6 CHD4	6.21e-03	32	69	2	IPR000330
Domain	SNF2_N	ERCC6 CHD4	6.21e-03	32	69	2	PF00176
Domain	Ig_E-set	FLNA FLNB PLXNA4	6.73e-03	104	69	3	IPR014756
Domain	EF-hand_8	CAPN2 EFCAB3	6.99e-03	34	69	2	PF13833
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	PRAM1 FLNA SCML2 BRD2 ATAD5 WDR33 GTSE1 ANKRD11 KMT2A ZDBF2 CHD4 TAF1 TAF1L CIC SLX4 INO80B	4.46e-11	954	69	16	36373674
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 SCML2 ERCC6 BRD2 ZNF280D ATAD5 GLYR1 UTP4 KMT2A CHD4 TAF1 GPATCH8 CIC	1.98e-10	608	69	13	36089195
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	PRR12 SCML2 WDR33 NELFA KMT2A CHD4 TAF1 CIC HMG20B	3.17e-09	268	69	9	33640491
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 SH3PXD2B GTSE1 ANKRD11 KMT2A COBL PRKCE LIMCH1 ATP2B1 DEPDC1B ZYX CIC NUAK2	1.29e-08	861	69	13	36931259
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRR12 SCML2 ERCC6 BRD2 ATAD5 UTP4 BMS1 ANKRD11 KMT2A LIMCH1 GPATCH8 TAF1L CIC INO80B LARP7 HMG20B	2.83e-08	1497	69	16	31527615
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLNA SCML2 BRD2 NELFA GTSE1 KMT2A CHD4 LIMCH1 GPATCH8 ZYX REXO1 CIC	3.74e-08	774	69	12	15302935
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	PRR12 FLNA FLNB ZNF280D ZDBF2 CHD4 TAF1 CIC HMG20B	1.44e-07	418	69	9	34709266
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 SCML2 BRD2 ATAD5 WDR33 GLYR1 UTP4 ANKRD11 KMT2A CHD4 GPATCH8 TAF1L CIC HMG20B	2.07e-07	1294	69	14	30804502
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	FLNA FLNB SH3PXD2B GLYR1 CAPN2 GTSE1 ANKRD11 CHD4	3.20e-07	332	69	8	37433992
Pubmed	Human transcription factor protein interaction networks.	PRR12 BRD2 ATAD5 WDR33 GLYR1 BMS1 KMT2A TAF1 GPATCH8 TAF1L CIC SLX4 INO80B HMG20B	6.82e-07	1429	69	14	35140242
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	ATAD5 WDR33 GTSE1 CHD4 TAF1 FYB1 TAF1L FMNL1	7.23e-07	370	69	8	22922362
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	FLNA FLNB SCCPDH ZNF280D WDR33 CAPN2 GTSE1 DEPDC1B LARP7 ITIH5	8.05e-07	670	69	10	22990118
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SCYL2 PRR12 FLNB ERCC6 GLYR1 BMS1 KMT2A COBL CHD4 INO80B LARP7	8.44e-07	847	69	11	35850772
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	FLNA FLNB SH3PXD2B TMEM131 ZDBF2 LIMCH1 NHLRC2 ZYX FMNL1	1.84e-06	568	69	9	37774976
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	FLNA FLNB WDR33 CHD4 TAF1 TAF1L	3.24e-06	203	69	6	22083510
Pubmed	Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.	FLNA FLNB	3.88e-06	2	69	2	17635842
Pubmed	Structural and functional aspects of filamins.	FLNA FLNB	3.88e-06	2	69	2	11336782
Pubmed	The variants at FLNA and FLNB contribute to the susceptibility of hypertension and stroke with differentially expressed mRNA.	FLNA FLNB	3.88e-06	2	69	2	33649519
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	3.88e-06	2	69	2	38804708
Pubmed	TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.	TAF1 TAF1L	3.88e-06	2	69	2	10070062
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	3.88e-06	2	69	2	22842574
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	3.88e-06	2	69	2	27571988
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	3.88e-06	2	69	2	34403156
Pubmed	Filamin depletion blocks endoplasmic spreading and destabilizes force-bearing adhesions.	FLNA FLNB	3.88e-06	2	69	2	21325628
Pubmed	Lipid-binding hSH3 domains in immune cell adapter proteins.	PRAM1 FYB1	3.88e-06	2	69	2	16831444
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	SCYL2 SH3PXD2B SCML2 WDR33 UTP4 GTSE1 BMS1 CIC	4.39e-06	472	69	8	38943005
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNA FLNB SCCPDH BRD2 WDR33 PLXNA4 KMT2A APOB CHD4 LIMCH1 ATP2B1 LARP7 SLC25A31	4.50e-06	1442	69	13	35575683
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	BRD2 NELFA GTSE1 BMS1 KMT2A ZDBF2 CHD4	5.05e-06	339	69	7	30415952
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ERCC6 BRD2 NELFA GTSE1 REXO1 SLX4	5.42e-06	222	69	6	37071664
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNA FLNB RNPEP GLYR1 UTP4 BMS1 KMT2A CHD4 LARP7	5.70e-06	653	69	9	22586326
Pubmed	Lost in transcription: molecular mechanisms that control HIV latency.	NELFA TAF1 LARP7	7.08e-06	19	69	3	23518577
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	FLNA FLNB SH3PXD2B SCML2 GLYR1 TMEM131 APOB GPATCH8 ATP2B1 QSOX2 SLX4	8.94e-06	1084	69	11	11544199
Pubmed	Filamins as integrators of cell mechanics and signalling.	FLNA FLNB	1.16e-05	3	69	2	11252955
Pubmed	Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading.	FLNA FLNB	1.16e-05	3	69	2	28175289
Pubmed	Regulated expression of TAF1 in 1-cell mouse embryos.	TAF1 TAF1L	1.16e-05	3	69	2	16822332
Pubmed	GPIbα regulates platelet size by controlling the subcellular localization of filamin.	FLNA FLNB	1.16e-05	3	69	2	22174152
Pubmed	TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.	TAF1 TAF1L	1.16e-05	3	69	2	11592977
Pubmed	Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.	FLNA FLNB	1.16e-05	3	69	2	12393796
Pubmed	Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.	TAF1 TAF1L	1.16e-05	3	69	2	12217962
Pubmed	TAF7: a possible transcription initiation check-point regulator.	TAF1 TAF1L	1.16e-05	3	69	2	16407123
Pubmed	Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.	FLNA FLNB	1.16e-05	3	69	2	11153914
Pubmed	Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation.	FLNA FLNB	1.16e-05	3	69	2	38989458
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	FLNA FLNB GTSE1 ZDBF2 LIMCH1 DEPDC1B	1.22e-05	256	69	6	33397691
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SCYL2 FLNA SH3PXD2B SCML2 WDR33 KMT2A TAF1 ZYX	1.32e-05	549	69	8	38280479
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SCML2 BRD2 ATAD5 WDR33 GLYR1 KMT2A TAF1	1.34e-05	394	69	7	27248496
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SCYL2 FLNA SCML2 ATAD5 UTP4 KMT2A CHD4 DEPDC1B ZYX CIC	1.51e-05	934	69	10	33916271
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BRD2 KMT2A CHD4 TAF1	1.55e-05	75	69	4	25593309
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	FLNA RHOBTB1 GLYR1 COBL ROS1 OSTF1 APOB CHD4 LIMCH1	1.79e-05	754	69	9	35906200
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	SCCPDH BRD2 PLGRKT GTSE1 BMS1 LIMCH1 ATP2B1 QSOX2 LARP7	1.79e-05	754	69	9	33060197
Pubmed	Regulation of cell adhesion to collagen via beta1 integrins is dependent on interactions of filamin A with vimentin and protein kinase C epsilon.	FLNA PRKCE	2.32e-05	4	69	2	20171211
Pubmed	The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.	FLNA FLNB	2.32e-05	4	69	2	11739414
Pubmed	Interaction of presenilins with the filamin family of actin-binding proteins.	FLNA FLNB	2.32e-05	4	69	2	9437013
Pubmed	Structural interaction and functional regulation of polycystin-2 by filamin.	FLNA FLNB	2.32e-05	4	69	2	22802962
Pubmed	Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling.	FLNA FLNB CHD4 LARP7	2.79e-05	87	69	4	24169447
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	BRD2 RNPEP ATAD5 NELFA CAPN2 KMT2A CHD4 TAF1 GPATCH8 LARP7	3.04e-05	1014	69	10	32416067
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNA FLNB	3.86e-05	5	69	2	19366992
Pubmed	Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.	FLNA FLNB	3.86e-05	5	69	2	12006559
Pubmed	Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.	FLNA FLNB	3.86e-05	5	69	2	17360453
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	FLNB BRD2 ATAD5 WDR33 GLYR1 KMT2A ZYX LARP7	4.14e-05	645	69	8	25281560
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	FLNA FLNB RNPEP CHD4 LIMCH1 ZYX LARP7	4.53e-05	477	69	7	31300519
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ZCWPW1 GLYR1 GTSE1 BMS1 CHD4 ATP2B1 CIC LARP7 HMG20B	4.85e-05	857	69	9	25609649
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	SCYL2 FLNA GLYR1 UTP4 BMS1 CHD4 LARP7	4.90e-05	483	69	7	36912080
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	BRD2 KMT2A CHD4 GPATCH8	5.41e-05	103	69	4	32744500
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	ATMIN FLNA ZCWPW1 BRD2 NELFA ANKRD11 KMT2A ZDBF2 NHLRC2 GPATCH8 QSOX2	5.72e-05	1327	69	11	32694731
Pubmed	Vector-capping: a simple method for preparing a high-quality full-length cDNA library.	FLNA FLNB	5.79e-05	6	69	2	16106752
Pubmed	ASB2 targets filamins A and B to proteasomal degradation.	FLNA FLNB	5.79e-05	6	69	2	18799729
Pubmed	Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.	TAF1 TAF1L	5.79e-05	6	69	2	19959467
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ATMIN PRR12 FLNA SH3PXD2B BRD2 GTSE1 ANKRD11 COBL REXO1 CIC	6.25e-05	1105	69	10	35748872
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FLNA FLNB ERCC6 NELFA GTSE1 TMEM131 ZYX	6.32e-05	503	69	7	16964243
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	FLNA FLNB NELFA CHD4 ZYX CIC LARP7	6.56e-05	506	69	7	30890647
Pubmed	The Z-disc proteins myotilin and FATZ-1 interact with each other and are connected to the sarcolemma via muscle-specific filamins.	FLNA FLNB	8.09e-05	7	69	2	16076904
Pubmed	Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.	APOB TAF1 TAF1L	8.71e-05	43	69	3	18722179
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	SCML2 BRD2 ATAD5 NELFA KMT2A CHD4 TAF1	9.06e-05	533	69	7	30554943
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLNA SH3PXD2B SCML2 SCCPDH ATAD5 UTP4 TMEM131 ZYX	9.27e-05	724	69	8	36232890
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	FLNA FLNB COBL	9.99e-05	45	69	3	22114352
Pubmed	Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.	TAF1 TAF1L	1.08e-04	8	69	2	2034279
Pubmed	MYH9-dependent polarization of ATG9B promotes colorectal cancer metastasis by accelerating focal adhesion assembly.	FLNA FLNB	1.08e-04	8	69	2	34131310
Pubmed	Selective recognition of acetylated histones by bromodomain proteins visualized in living cells.	BRD2 TAF1	1.08e-04	8	69	2	14731392
Pubmed	MEKK4 signaling regulates filamin expression and neuronal migration.	FLNA FLNB	1.08e-04	8	69	2	17145501
Pubmed	Filamin B mutations cause chondrocyte defects in skeletal development.	FLNA FLNB	1.08e-04	8	69	2	17510210
Pubmed	Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.	TAF1 TAF1L	1.08e-04	8	69	2	8468051
Pubmed	Genetic mapping in the region of the mouse X-inactivation center.	TAF1 TAF1L	1.08e-04	8	69	2	1974879
Pubmed	Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice.	TAF1 TAF1L	1.08e-04	8	69	2	31012985
Pubmed	High-density molecular map of the central span of the mouse X chromosome.	TAF1 TAF1L	1.08e-04	8	69	2	1675191
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FLNA FLNB ZNF280D RNPEP GLYR1 UTP4 BMS1 APOB CHD4 ATP2B1 LARP7	1.08e-04	1425	69	11	30948266
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	ZNF280D GLYR1 CHD4 TAF1	1.11e-04	124	69	4	20850016
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	FLNA FLNB SCCPDH GTSE1 BMS1 KMT2A COBL CHD4 LIMCH1 ATP2B1 LARP7	1.18e-04	1440	69	11	30833792
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FLNA SCCPDH PLGRKT WDR33 UTP4 CHD4 GPATCH8 ATP2B1 QSOX2 SLX4	1.26e-04	1203	69	10	29180619
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	SCYL2 FLNA FLNB GLYR1 CHD4	1.30e-04	245	69	5	21182205
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SCYL2 FLNA FLNB SH3PXD2B LIMCH1 ATP2B1 ZYX	1.30e-04	565	69	7	25468996
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	SH3PXD2B OSTF1 FYB1	1.37e-04	50	69	3	19807924
Pubmed	The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.	TAF1 TAF1L	1.38e-04	9	69	2	12665565
Pubmed	Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.	TAF1 TAF1L	1.38e-04	9	69	2	7874112
Pubmed	HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.	TAF1 TAF1L	1.38e-04	9	69	2	9751712
Pubmed	Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.	FLNA FLNB	1.38e-04	9	69	2	11807098
Pubmed	Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins.	UTP4 SLX4 ITIH5	1.45e-04	51	69	3	11853319
Pubmed	Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death.	BRD2 TAF1 TAF1L	1.54e-04	52	69	3	35361962
Pubmed	Functional proteomics mapping of a human signaling pathway.	SCYL2 FLNA FLNB ERCC6 RNPEP ZYX FMNL1	1.71e-04	591	69	7	15231748
Pubmed	Filamin-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeletal elements.	FLNA FLNB	1.73e-04	10	69	2	24436304
Pubmed	Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.	TAF1 TAF1L	1.73e-04	10	69	2	2055107
Interaction	SMC5 interactions	PRAM1 FLNA SCML2 BRD2 ATAD5 WDR33 GTSE1 ANKRD11 KMT2A ZDBF2 CHD4 TAF1 TAF1L CIC SLX4 INO80B	1.92e-07	1000	69	16	int:SMC5
Interaction	H3C3 interactions	FSIP2 SCML2 BRD2 ZNF280D ATAD5 GLYR1 UTP4 KMT2A CHD4 TAF1 CIC	8.86e-07	495	69	11	int:H3C3
Interaction	DHX40 interactions	BRD2 WDR33 BMS1 ANKRD11 ZDBF2 TAF1 GPATCH8 SLX4	2.12e-06	249	69	8	int:DHX40
Interaction	NPM1 interactions	FLNA FLNB WDR33 WDR87 GLYR1 UTP4 BMS1 KMT2A CHD4 LIMCH1 ZYX FMNL1 CIC SLX4 INO80B LARP7	2.18e-06	1201	69	16	int:NPM1
Interaction	ACTC1 interactions	SCYL2 FLNA FLNB NELFA COBL PRKCE CHD4 EFCAB3 ZYX CIC SLX4 LARP7	3.69e-06	694	69	12	int:ACTC1
Interaction	ITGB2 interactions	FLNA FLNB SH3PXD2B KMT2A PRKCE CHD4	6.02e-06	132	69	6	int:ITGB2
Interaction	H2AC4 interactions	SCML2 ERCC6 BRD2 ATAD5 GLYR1 KMT2A CHD4 ATP2B1 SLX4 LARP7	8.21e-06	506	69	10	int:H2AC4
Interaction	NUP43 interactions	FSIP2 FLNA ZNF280D GLYR1 BMS1 ANKRD11 KMT2A ZDBF2 GPATCH8 SLX4 LARP7	8.32e-06	625	69	11	int:NUP43
Interaction	ACTB interactions	FSIP2 FLNA FLNB SCCPDH COBL PRKCE OSTF1 CHD4 TPGS2 LIMCH1 ZYX SLX4 INO80B LARP7	1.49e-05	1083	69	14	int:ACTB
Interaction	H1-2 interactions	FLNA ZCWPW1 BRD2 GLYR1 BMS1 KMT2A CHD4 LIMCH1 ATP2B1 FMNL1 LARP7	1.51e-05	666	69	11	int:H1-2
Interaction	CHD4 interactions	CCT8L2 ERCC6 BRD2 GLYR1 CAPN2 BMS1 KMT2A CHD4 GPATCH8 CIC SLX4 LARP7 HMG20B	1.52e-05	938	69	13	int:CHD4
Interaction	SSRP1 interactions	BRD2 RHOBTB1 NELFA ANKRD11 KMT2A CHD4 ATP2B1 REXO1 FMNL1 CIC LARP7	1.96e-05	685	69	11	int:SSRP1
Interaction	GATAD2B interactions	ERCC6 BRD2 TMEM131 CHD4 CIC SLX4 LARP7	2.05e-05	245	69	7	int:GATAD2B
Interaction	ZNF330 interactions	BRD2 ATAD5 GLYR1 BMS1 ANKRD11 KMT2A TAF1 GPATCH8 LARP7	2.05e-05	446	69	9	int:ZNF330
Interaction	CAPRIN2 interactions	FLNA FLNB BRD2	2.08e-05	16	69	3	int:CAPRIN2
Interaction	NOP56 interactions	SCYL2 ERCC6 BRD2 ATAD5 GLYR1 UTP4 BMS1 ANKRD11 CHD4 LARP7	2.30e-05	570	69	10	int:NOP56
Interaction	TAF1 interactions	SCCPDH BRD2 UTP4 KMT2A TAF1 TAF1L CIC	2.99e-05	260	69	7	int:TAF1
Interaction	CENPA interactions	ERCC6 BRD2 ATAD5 GLYR1 BMS1 ANKRD11 KMT2A TAF1	4.30e-05	377	69	8	int:CENPA
Interaction	H3-3A interactions	SCML2 ERCC6 BRD2 ZNF280D ATAD5 GLYR1 KMT2A CHD4 TAF1 GPATCH8 CIC	4.43e-05	749	69	11	int:H3-3A
Interaction	LEO1 interactions	FLNB CCT8L2 ERCC6 BRD2 KMT2A CHD4 LARP7	4.58e-05	278	69	7	int:LEO1
Interaction	MEX3A interactions	FLNA FLNB SH3PXD2B GLYR1 CAPN2 GTSE1 ANKRD11 CHD4	4.90e-05	384	69	8	int:MEX3A
Interaction	CSNK2B interactions	ERCC6 BRD2 BMS1 ANKRD11 KMT2A CHD4 CIC INO80B LARP7 NUAK2	5.01e-05	625	69	10	int:CSNK2B
Interaction	CHD8 interactions	BRD2 KMT2A TAF1 CIC SLX4 LARP7	5.18e-05	193	69	6	int:CHD8
Interaction	ACTR8 interactions	CCT8L2 BRD2 KMT2A INO80B	6.04e-05	62	69	4	int:ACTR8
Interaction	KRT73 interactions	CHD4 NHLRC2 CIC LARP7	6.85e-05	64	69	4	int:KRT73
Interaction	FEV interactions	PRR12 KMT2A TAF1 GPATCH8 CIC HMG20B	6.86e-05	203	69	6	int:FEV
Interaction	H2BC3 interactions	SCML2 ERCC6 BRD2 ATAD5 WDR33 KMT2A CHD4 LARP7	7.24e-05	406	69	8	int:H2BC3
Interaction	H1-4 interactions	PRAM1 BRD2 WDR87 GLYR1 BMS1 KMT2A CHD4 GPATCH8 FMNL1 LARP7	7.50e-05	656	69	10	int:H1-4
Interaction	MDC1 interactions	FLNA FLNB BRD2 ATAD5 WDR33 CHD4 DEPDC1B SLX4	8.29e-05	414	69	8	int:MDC1
Interaction	PAF1 interactions	ERCC6 KMT2A CHD4 CIC SLX4 LARP7	9.18e-05	214	69	6	int:PAF1
Interaction	COIL interactions	BRD2 RHOBTB1 NELFA UTP4 BMS1 ANKRD11 CHD4 TAF1 LARP7	1.07e-04	552	69	9	int:COIL
Interaction	TERF2IP interactions	ATAD5 WDR33 NELFA ANKRD11 KMT2A TAF1 CIC SLX4 LARP7	1.07e-04	552	69	9	int:TERF2IP
Interaction	BAZ2A interactions	BRD2 CHD4 CIC LARP7	1.15e-04	73	69	4	int:BAZ2A
Interaction	H2BC21 interactions	PRR12 SCML2 BRD2 ZNF280D ATAD5 GLYR1 KMT2A CHD4 FYB1 LARP7	1.22e-04	696	69	10	int:H2BC21
Interaction	AR interactions	PRR12 FLNA SCML2 BRD2 WDR33 NELFA KMT2A CHD4 LIMCH1 TAF1 CIC HMG20B	1.24e-04	992	69	12	int:AR
Interaction	H4C4 interactions	CHD4 CIC LARP7	1.32e-04	29	69	3	int:H4C4
Interaction	GART interactions	FLNA FLNB ZYX CIC SLX4 LARP7	1.36e-04	230	69	6	int:GART
Interaction	HDLBP interactions	FLNA CCT8L2 WDR33 GLYR1 KMT2A ROS1 CHD4 LIMCH1 ZYX SLX4 LARP7	1.44e-04	855	69	11	int:HDLBP
Interaction	CTR9 interactions	ERCC6 KMT2A TMEM131 CHD4 SLX4 LARP7	1.46e-04	233	69	6	int:CTR9
Interaction	H2BC8 interactions	SCML2 BRD2 ZNF280D ATAD5 NELFA GLYR1 BMS1 KMT2A CHD4	1.47e-04	576	69	9	int:H2BC8
Interaction	PRPF6 interactions	CCT8L2 CHD4 NHLRC2 DEPDC1B CIC SLX4 LARP7	1.50e-04	336	69	7	int:PRPF6
Interaction	UBTF interactions	BRD2 UTP4 CHD4 TAF1 SLX4 LARP7	1.50e-04	234	69	6	int:UBTF
Interaction	RNF2 interactions	FLNB SCML2 GLYR1 UTP4 BMS1 KMT2A CHD4 ATP2B1 CIC LARP7 HMG20B	1.61e-04	866	69	11	int:RNF2
Interaction	PHF21A interactions	FLNA FLNB ZDBF2 TAF1 ZYX CIC HMG20B	1.70e-04	343	69	7	int:PHF21A
Interaction	EVL interactions	UTP4 NHLRC2 FYB1 ZYX	1.89e-04	83	69	4	int:EVL
Interaction	POLR1E interactions	BRD2 ATAD5 UTP4 BMS1 KMT2A ZDBF2 TAF1	1.92e-04	350	69	7	int:POLR1E
Interaction	H4C5 interactions	CHD4 CIC LARP7	2.13e-04	34	69	3	int:H4C5
Interaction	CBX5 interactions	SH3PXD2B BRD2 ZNF280D GLYR1 CHD4 CIC LARP7	2.13e-04	356	69	7	int:CBX5
Interaction	TAF5 interactions	BRD2 TAF1 TAF1L CIC	2.16e-04	86	69	4	int:TAF5
Interaction	MOB2 interactions	SCYL2 RHOBTB1 ATP2B1 DEPDC1B	2.26e-04	87	69	4	int:MOB2
Interaction	DDX23 interactions	ERCC6 BRD2 BMS1 ANKRD11 CHD4 TAF1 GPATCH8 LARP7	2.29e-04	480	69	8	int:DDX23
Interaction	RBPJ interactions	BRD2 RHOBTB1 KMT2A CHD4 CIC HMG20B	2.33e-04	254	69	6	int:RBPJ
Interaction	POLR1G interactions	BRD2 ATAD5 BMS1 ANKRD11 KMT2A TAF1 CIC LARP7	2.59e-04	489	69	8	int:POLR1G
Interaction	BRD3 interactions	SCML2 BRD2 ATAD5 KMT2A CHD4 TAF1 INO80B LARP7	2.78e-04	494	69	8	int:BRD3
Interaction	UTP4 interactions	UTP4 BMS1 ANKRD11 ZDBF2 TAF1	2.93e-04	170	69	5	int:UTP4
Interaction	XRCC6 interactions	SCML2 PLGRKT GLYR1 BMS1 KMT2A CHD4 TAF1 TAF1L FMNL1 CIC LARP7	2.93e-04	928	69	11	int:XRCC6
Interaction	DHX15 interactions	FLNB CHD4 ZYX CIC SLX4 INO80B LARP7 HMG20B	3.09e-04	502	69	8	int:DHX15
Interaction	SRSF6 interactions	WDR33 GLYR1 BMS1 KMT2A CHD4 GPATCH8 CIC LARP7	3.13e-04	503	69	8	int:SRSF6
Interaction	MTA3 interactions	ERCC6 BRD2 CHD4 CIC HMG20B	3.17e-04	173	69	5	int:MTA3
Interaction	ZMYM2 interactions	ZNF280D PSG8 CHD4 CIC SLX4 HMG20B	3.30e-04	271	69	6	int:ZMYM2
Interaction	BRCA2 interactions	FLNA CCT8L2 ERCC6 KMT2A CHD4 SLX4 HMG20B	3.37e-04	384	69	7	int:BRCA2
Interaction	SMARCC1 interactions	BRD2 RHOBTB1 KMT2A CHD4 CIC SLX4 LARP7	3.37e-04	384	69	7	int:SMARCC1
Interaction	CBX3 interactions	SCML2 BRD2 ZNF280D ATAD5 GLYR1 KMT2A CHD4 CIC SLX4	3.44e-04	646	69	9	int:CBX3
Interaction	HSP90AB3P interactions	PRKCE ANKMY2 LARP7 NUAK2	3.57e-04	98	69	4	int:HSP90AB3P
Interaction	H4C8 interactions	CHD4 CIC LARP7	3.73e-04	41	69	3	int:H4C8
Interaction	PSG8 interactions	RHOBTB1 CAPN2 PSG8	3.73e-04	41	69	3	int:PSG8
Interaction	VIM interactions	SCYL2 RHOBTB1 PRKCE CHD4 NHLRC2 ZYX CIC SLX4 LARP7 HMG20B	3.89e-04	804	69	10	int:VIM
Interaction	H4C14 interactions	BRD2 CHD4 CIC LARP7	4.00e-04	101	69	4	int:H4C14
Interaction	H4C15 interactions	CHD4 CIC LARP7	4.01e-04	42	69	3	int:H4C15
Interaction	ASB2 interactions	FLNA FLNB KMT2A	4.01e-04	42	69	3	int:ASB2
Interaction	LSP1 interactions	CAPN2 NHLRC2 FMNL1	4.30e-04	43	69	3	int:LSP1
Interaction	PCBP2 interactions	SCYL2 FLNA CHD4 CIC SLX4 LARP7	4.56e-04	288	69	6	int:PCBP2
Interaction	NAA40 interactions	SCYL2 FLNA SCML2 ATAD5 UTP4 KMT2A CHD4 LIMCH1 DEPDC1B ZYX CIC	4.58e-04	978	69	11	int:NAA40
Interaction	FASLG interactions	SH3PXD2B KMT2A OSTF1 FYB1	4.64e-04	105	69	4	int:FASLG
Interaction	H4C11 interactions	CHD4 CIC LARP7	4.92e-04	45	69	3	int:H4C11
Interaction	RPL31 interactions	BRD2 ATAD5 GLYR1 BMS1 ANKRD11 CHD4 TAF1 INO80B LARP7	4.99e-04	680	69	9	int:RPL31
Interaction	VASP interactions	SCYL2 UTP4 LIMCH1 NHLRC2 FYB1 ZYX	5.08e-04	294	69	6	int:VASP
Interaction	MBD3 interactions	ERCC6 BRD2 KMT2A CHD4 CIC LARP7	5.17e-04	295	69	6	int:MBD3
Interaction	DNAJC9 interactions	BRD2 GLYR1 UTP4 BMS1 ROS1 LARP7	5.27e-04	296	69	6	int:DNAJC9
Interaction	DBN1 interactions	FLNA FLNB BRD2 RHOBTB1 GTSE1 COBL LIMCH1	5.52e-04	417	69	7	int:DBN1
Interaction	HSPA1B interactions	ROS1 CHD4 NHLRC2 FMNL1 CIC LARP7	5.75e-04	301	69	6	int:HSPA1B
Interaction	ADNP interactions	CCT8L2 GLYR1 CHD4 CIC SLX4	6.01e-04	199	69	5	int:ADNP
Interaction	TBR1 interactions	PRR12 BRD2 CIC HMG20B	6.12e-04	113	69	4	int:TBR1
Interaction	BRD2 interactions	BRD2 ATAD5 CHD4 TAF1 SLX4 INO80B LARP7	6.53e-04	429	69	7	int:BRD2
Interaction	LIMA1 interactions	FLNA FLNB GTSE1 COBL DEPDC1B FMNL1 CIC	6.53e-04	429	69	7	int:LIMA1
Interaction	ZNF687 interactions	BRD2 CHD4 CIC SLX4	6.54e-04	115	69	4	int:ZNF687
Interaction	H4C3 interactions	CHD4 CIC LARP7	6.71e-04	50	69	3	int:H4C3
Interaction	SENP6 interactions	ANKRD11 ZDBF2 SLX4	6.71e-04	50	69	3	int:SENP6
Interaction	BAZ1B interactions	ERCC6 BRD2 ATAD5 ROS1 CHD4	6.73e-04	204	69	5	int:BAZ1B
Interaction	FOXP3 interactions	ATAD5 WDR33 GTSE1 CHD4 TAF1 FYB1 FMNL1	6.80e-04	432	69	7	int:FOXP3
Interaction	MEN1 interactions	SCYL2 PRR12 SCML2 ERCC6 WDR33 GLYR1 BMS1 KMT2A COBL CHD4 TAF1	6.99e-04	1029	69	11	int:MEN1
Interaction	PTBP1 interactions	FLNA FLNB RHOBTB1 CHD4 NHLRC2 CIC SLX4	7.28e-04	437	69	7	int:PTBP1
Interaction	SLX4 interactions	FLNA ERCC6 BRD2 NELFA GTSE1 CHD4 REXO1 SLX4	7.32e-04	572	69	8	int:SLX4
Interaction	WRNIP1 interactions	ATMIN TAF1 CIC SLX4	7.43e-04	119	69	4	int:WRNIP1
Interaction	FRMPD2 interactions	LIMCH1 SLC25A31	7.46e-04	12	69	2	int:FRMPD2
Interaction	C17orf78 interactions	ATP2B1 ZYX	7.46e-04	12	69	2	int:C17orf78
Interaction	MACROH2A2 interactions	BRD2 GLYR1 BMS1 CHD4 LARP7	7.83e-04	211	69	5	int:MACROH2A2
Interaction	CHTOP interactions	BRD2 CHD4 NHLRC2 CIC LARP7	8.00e-04	212	69	5	int:CHTOP
Interaction	TSR1 interactions	UTP4 CHD4 NHLRC2 CIC INO80B LARP7	8.17e-04	322	69	6	int:TSR1
Interaction	H4C2 interactions	CHD4 CIC LARP7	8.41e-04	54	69	3	int:H4C2
ToppCell	10x5'v1-week_17-19-Myeloid_monocytic-monocyte-CD14_monocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRAM1 FLNA CAPN2 ADAM8 FYB1 ZYX	6.80e-07	200	69	6	07197f95282ee607db17b92fea1376051e65fc50
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA OSTF1 ADAM8 ZYX	6.34e-06	168	69	5	3611605114f6b668b44728d6563cd02389e106af
ToppCell	facs-Marrow-Granulocytes-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA OSTF1 ADAM8 ZYX	6.52e-06	169	69	5	ee1969755180df58d32904e2bb4192da9373d03e
ToppCell	facs-BAT-Fat-18m-Myeloid-nan\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA RNPEP FYB1 FMNL1 NUAK2	7.10e-06	172	69	5	36fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCell	facs-BAT-Fat-18m-Myeloid\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 ADAM8 FYB1 ZYX FMNL1	7.10e-06	172	69	5	8e91831804a120037c71cd4e74af686f3c32d31c
ToppCell	facs-BAT-Fat-18m-Myeloid-myeloid_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 ADAM8 FYB1 ZYX FMNL1	7.10e-06	172	69	5	ea4da9aab7a2ff854df21da01d11c9ed99e41fb4
ToppCell	facs-Lung-24m-Hematologic-myeloid\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA ADAM8 FYB1 ZYX FMNL1	9.85e-06	184	69	5	c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB CAPN2 COBL LIMCH1 ZC3H12C	1.06e-05	187	69	5	d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNA ANKRD11 CHD4 ATP2B1 ITIH5	1.15e-05	190	69	5	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNA ADAM8 FYB1 ATP2B1 FMNL1	1.34e-05	196	69	5	fe8d3f45a64323947c36b127355d5940eb56c0ca
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	RNPEP GLYR1 GTSE1 DEPDC1B QSOX2	1.34e-05	196	69	5	36ed1918f70b6f5760bb088b15ce422998055cc7
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNA ADAM8 FYB1 ATP2B1 FMNL1	1.34e-05	196	69	5	526d037bb12d81f1c235c60ddc787fbad0bbad77
ToppCell	(0)_Myeloid-(01)_Dendritic_cell-(010)_cDC\|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)	PRAM1 FLNA CAPN2 ADAM8 ZYX	1.40e-05	198	69	5	4abc274edac40f8836255fac2371ffd98a32cccd
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	PRAM1 SH3PXD2B FYB1 ATP2B1 FMNL1	1.40e-05	198	69	5	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	10x5'v1-week_17-19-Myeloid_monocytic-monocyte-promonocyte\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	PRAM1 FLNA CAPN2 ZYX FMNL1	1.44e-05	199	69	5	b725a9c9bdc307641958a8f3ab2f6af9e7a0163d
ToppCell	18-Distal-Mesenchymal-Mesenchyme_RSPO2+\|Distal / Age, Tissue, Lineage and Cell class	OSTF1 LIMCH1 OGN ATP2B1 ZYX	1.44e-05	199	69	5	95403988caef322314f4ed15415ad1a9a987adc1
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	FLNA CAPN2 ANKRD11 KMT2A CHD4	1.47e-05	200	69	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	LIMCH1 OGN ATP2B1 ZYX ITIH5	1.47e-05	200	69	5	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	Myeloid-E_(Neutrophils)\|World / shred on cell class and cell subclass (v4)	PRAM1 OSTF1 ADAM8 FMNL1	7.60e-05	145	69	4	6ae7dbc62116b4d0610fb55703679488e8da4733
ToppCell	Myeloid-Myeloid-E_(Neutrophils)\|Myeloid / shred on cell class and cell subclass (v4)	PRAM1 ST3GAL6 OSTF1 ADAM8	8.67e-05	150	69	4	1bffb8d86b737ac43be902d9468041aef3542f1f
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZCWPW1 APOB DNAAF11 FYB1	1.01e-04	156	69	4	f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCell	Control-Epithelial_alveolar-AT_2-Differentiating_AT1\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRR12 DNAAF11 REXO1 SLX4	1.03e-04	157	69	4	4766f7d545bf2d775390589460677519cb92f4d5
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 FMNL1 NUAK2	1.06e-04	158	69	4	121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 FMNL1 NUAK2	1.11e-04	160	69	4	bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCell	COVID_non-vent-Lymphocytic-Dendritic-pDC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	FLNB SCML2 PLXNA4 COBL	1.11e-04	160	69	4	61f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCell	COVID_non-vent-Lymphocytic-Dendritic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	FLNB SCML2 PLXNA4 COBL	1.11e-04	160	69	4	34b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell	facs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 FMNL1 NUAK2	1.17e-04	162	69	4	484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAPN2 APOB ATP2B1 ITIH5	1.17e-04	162	69	4	bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCell	facs-Lung-nan-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 FMNL1 NUAK2	1.17e-04	162	69	4	3fd6aaf0fbaffc7ab38aa25e46c37ef511e1e704
ToppCell	facs-Lung-nan-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 FMNL1 NUAK2	1.17e-04	162	69	4	8134f73eb76693f4f1845f643042fdc1e81c274c
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 FMNL1 NUAK2	1.17e-04	162	69	4	bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 FMNL1 NUAK2	1.19e-04	163	69	4	bbbc3f0ce2616d07136f69ce682ba1d3790711d9
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FLNA PLXNA4 COBL ADAM8	1.19e-04	163	69	4	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	facs-Lung-3m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 FMNL1 NUAK2	1.22e-04	164	69	4	11dfd84f5fb90de330858e1e852848832734e004
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 ADAM8 FYB1 FMNL1	1.22e-04	164	69	4	45a6d809d92fd4eee906da3c812282bacffc9f2f
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 ADAM8 FYB1 FMNL1	1.22e-04	164	69	4	aa4358311fc767c292897e3328309d1bcda392d4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM8 OGN DEPDC1B CIC	1.25e-04	165	69	4	50f1fa7434ebb777e15d5273d1ff41070cff6db3
ToppCell	facs-Lung-nan-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 FMNL1 NUAK2	1.25e-04	165	69	4	720649f330382ea2a68c64a5344160a048afb8f1
ToppCell	facs-Lung-3m-Hematologic-myeloid\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADAM8 FYB1 FMNL1 NUAK2	1.28e-04	166	69	4	7bf7c2854cf7d85b3ae07256bbe86ae9184d6b57
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA FYB1 ZYX	1.28e-04	166	69	4	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	droplet-Lung-nan-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 OSTF1 ADAM8 FMNL1	1.34e-04	168	69	4	da1eee804456d910c17f145a5ce79c74a808a2c2
ToppCell	PCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PRAM1 ADAM8 FYB1 FMNL1	1.34e-04	168	69	4	907692c1f03d3c9889ba1bed5a4844e2c379db8e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 FMNL1 NUAK2	1.34e-04	168	69	4	4b5be7c6662eceddf90a65015f12908278d1664e
ToppCell	droplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 FMNL1 NUAK2	1.34e-04	168	69	4	689c41f6e9f65381570991cc311cba49a57ec955
ToppCell	facs-Lung-24m-Hematologic-myeloid-non-classical_monocyte\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 FMNL1 NUAK2	1.34e-04	168	69	4	c861f80aa12caf54a94d93e38539ff41dc5227a6
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA OSTF1 ADAM8	1.37e-04	169	69	4	f38b52972a6c492ce2fd520a26bb3fc8db23bf85
ToppCell	facs-BAT-Fat-18m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 ADAM8 FYB1 ZYX	1.37e-04	169	69	4	d3e6c75e5eda133fb6535cfe6c6a1026641f26ac
ToppCell	droplet-Lung-nan-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 FMNL1 NUAK2	1.37e-04	169	69	4	ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA OSTF1 ADAM8	1.37e-04	169	69	4	5320da1d61806b53e0bd96bbdfdb8fd69246681b
ToppCell	droplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 FMNL1 NUAK2	1.37e-04	169	69	4	c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCell	facs-Marrow-Granulocytes-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA ADAM8 ZYX	1.37e-04	169	69	4	2341eddfedaad8cee779c37bb87f7def058588ca
ToppCell	facs-Marrow-Granulocytes-18m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA ADAM8 ZYX	1.37e-04	169	69	4	94871936ccfc73b56d425373b989b87c059d4493
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FSIP2 SCCPDH ST3GAL6 NUAK2	1.40e-04	170	69	4	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	facs-Marrow-Granulocytes\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA ADAM8 ZYX	1.44e-04	171	69	4	1701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCell	droplet-Lung-18m-Hematologic-myeloid\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNA FYB1 ZYX FMNL1	1.44e-04	171	69	4	33869b9fab2c94cb33f1cc659073fcf2bb30c22d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRAM1 GTSE1 DEPDC1B FMNL1	1.44e-04	171	69	4	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA FYB1 ZYX FMNL1	1.47e-04	172	69	4	66823536288c7009ce01b5177794a3e874e94570
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRAM1 ATAD5 GTSE1 FMNL1	1.47e-04	172	69	4	ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell	IIH-CD8-naive_CD4\|IIH / Condition, Cell_class and T cell subcluster	ZCWPW1 ERCC6 ATAD5 UTP4	1.50e-04	173	69	4	4f2843371d18af766c1892529ce286f56c956fde
ToppCell	10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic\|Lung / Manually curated celltypes from each tissue	ATAD5 GTSE1 OGN DEPDC1B	1.50e-04	173	69	4	62e0c18cfed9645e34a9d7029c94a8554f773714
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCYL2 PLXNA4 ZC3H12C ADAM8	1.54e-04	174	69	4	7be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell	droplet-Lung-nan-21m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OSTF1 FYB1 FMNL1 NUAK2	1.54e-04	174	69	4	763ca53339d9e236da8463f2a9d1bd39d4385d75
ToppCell	droplet-Marrow-nan-18m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 OSTF1 ADAM8 ZYX	1.54e-04	174	69	4	4b749ac9f05776c0c56b74daca833bd0b5704299
ToppCell	droplet-Marrow-nan-21m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA OSTF1 ADAM8	1.60e-04	176	69	4	f7d8eb90489a6d22240179abeb0aa16ac24615d3
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COBL LIMCH1 OGN ITIH5	1.64e-04	177	69	4	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	droplet-Lung\|droplet / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OSTF1 FYB1 ZYX FMNL1	1.64e-04	177	69	4	e1555e45880c04fcc89e1234e97897d27246250f
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 GTSE1 DEPDC1B SLX4	1.64e-04	177	69	4	844017225e9039d1bc621a9630a30c2e9a51b36d
ToppCell	368C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 GTSE1 DEPDC1B SLX4	1.64e-04	177	69	4	26c25d10aa511b64cc7db43a8deea7b5d31bca96
ToppCell	droplet-Marrow-nan-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 OSTF1 ADAM8 ZYX	1.64e-04	177	69	4	5d70fe2b0592362d664b3b4c84eb450ec2335957
ToppCell	droplet-Lung\|droplet / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OSTF1 FYB1 ZYX FMNL1	1.64e-04	177	69	4	dd35d534ba09237a37ac58cca184e5d84d3b36ac
ToppCell	droplet-Marrow-nan-18m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 OSTF1 ADAM8 ZYX	1.64e-04	177	69	4	48bcf603ec9593eedd81f3831cf9fde89fad368f
ToppCell	droplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC6 ST3GAL6 ADAM8 FMNL1	1.68e-04	178	69	4	09d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLNA RNPEP FMNL1 ITIH5	1.68e-04	178	69	4	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNB SCML2 PLXNA4 COBL	1.71e-04	179	69	4	124da6f882968dc0d05f3edd8f3b4d61617cc214
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNB SCML2 PLXNA4 COBL	1.71e-04	179	69	4	edc5ef693dc4e7ea70717b77fb908fc784dce3a2
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PLXNA4 LIMCH1 OGN ITIH5	1.75e-04	180	69	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIMCH1 OGN ZYX ITIH5	1.79e-04	181	69	4	9e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCML2 GTSE1 DEPDC1B SLX4	1.79e-04	181	69	4	3fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCell	facs-Marrow-T-cells-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB CAPN2 ZC3H12C FYB1	1.79e-04	181	69	4	7286700396676fdc41d9723979b8b408177aceb9
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	FLNB COBL ROS1 LIMCH1	1.86e-04	183	69	4	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRAM1 ADAM8 FYB1 FMNL1	1.86e-04	183	69	4	cff3197e9ff401362501db2317c86adc6d24b595
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRAM1 ADAM8 FYB1 FMNL1	1.86e-04	183	69	4	f803dd2881ceaed6327e21a1a51bc3d3ccf4b5f8
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PRAM1 ADAM8 FYB1 FMNL1	1.86e-04	183	69	4	4bd6883daf2dbe8c1b49b776b48d41f9890d1cb4
ToppCell	facs-Lung-EPCAM-24m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ADAM8 ZYX FMNL1	1.86e-04	183	69	4	b082fb7afab13106ddeb764fab4c32c485123f74
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNB SCML2 PLXNA4 COBL	1.86e-04	183	69	4	3b123571e10c132227aff65648b4b3c6acb4bd00
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FLNB SCML2 PLXNA4 COBL	1.86e-04	183	69	4	df6fd0927b6e4cf9a1583969a68096e4bccfbace
ToppCell	droplet-Marrow-nan-21m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA RNPEP OSTF1	1.90e-04	184	69	4	d071f53ad9e957dc0f8ae9c53aaa31cfebcf815e
ToppCell	facs-Marrow\|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA OSTF1 ZYX	1.94e-04	185	69	4	e40f0a0439834c3025d6c7832977be4e37a94c44
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	FLNB ATAD5 GTSE1 ZC3H12C	1.94e-04	185	69	4	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	healthy_donor-Lymphocytic-Dendritic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	FLNB SCML2 PLXNA4 COBL	1.98e-04	186	69	4	916f2aeea4989ba7a29e071e348a51010f010223
ToppCell	healthy_donor-Lymphocytic-Dendritic-pDC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	FLNB SCML2 PLXNA4 COBL	1.98e-04	186	69	4	45f66619e45d590c7365a51782d4ac46b7d31fde
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCCPDH ST3GAL6 COBL NUAK2	2.02e-04	187	69	4	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB COBL LIMCH1 DEPDC1B	2.02e-04	187	69	4	f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCell	control-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FLNB SCML2 PLXNA4 COBL	2.02e-04	187	69	4	c78aee98b32719aa45811b620fc97be1ecf5fd53
ToppCell	droplet-Marrow-nan-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA RNPEP OSTF1 ZYX	2.06e-04	188	69	4	0a874578f5692a896ea3071a17d87cdeb242fb11
ToppCell	droplet-Marrow-nan-18m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRAM1 FLNA OSTF1 ZYX	2.06e-04	188	69	4	fa7a612b0a2b35de5f76a0408168dabe5db00773
ToppCell	367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	ATAD5 GTSE1 TPGS2 DEPDC1B	2.06e-04	188	69	4	f5102e8d95506c25c675094b86162a6a50087b64
ToppCell	normal-na-Lymphocytic\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ATAD5 GTSE1 OGN DEPDC1B	2.11e-04	189	69	4	1d382f8eb998c6a30e09fddc9a427afc8f5f7323
ToppCell	normal-na-Lymphocytic-lymphocyte\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ATAD5 GTSE1 OGN DEPDC1B	2.11e-04	189	69	4	b83fd81ecc5ef363be7435ee12cb7079e2434af7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLNB COBL LIMCH1 DEPDC1B	2.11e-04	189	69	4	e32172ad09e93f6ac6ea2b92145b2b73003f7970
Drug	40-a	FLNA FLNB BRD2 KMT2A	1.99e-06	30	69	4	CID000211218
Drug	Cloperastine hydrochloride [14984-68-0]; Down 200; 11uM; PC3; HT_HG-U133A	GLYR1 GTSE1 LIMCH1 NHLRC2 TAF1 BTN3A1 INO80B	2.09e-06	195	69	7	3710_DN
Disease	myofibrillar myopathy 5 (implicated_via_orthology)	FLNA FLNB	1.57e-05	3	68	2	DOID:0080096 (implicated_via_orthology)
Disease	distal muscular dystrophy 4 (implicated_via_orthology)	FLNA FLNB	1.57e-05	3	68	2	DOID:0111190 (implicated_via_orthology)
Disease	Small cell carcinoma of lung	KMT2A ZDBF2 TAF1L	2.67e-04	54	68	3	C0149925
Disease	Disproportionate short stature	FLNA FLNB SH3PXD2B	7.58e-04	77	68	3	C0878659
Disease	osteochondrodysplasia (is_implicated_in)	FLNA FLNB	8.72e-04	19	68	2	DOID:2256 (is_implicated_in)
Disease	Pseudoaphakia	ERCC6 ATP2B1	1.40e-03	24	68	2	C0524524
Disease	Lens Opacities	ERCC6 ATP2B1	1.40e-03	24	68	2	C1510497
Disease	Acute monocytic leukemia	KMT2A SLX4	1.64e-03	26	68	2	C0023465
Disease	bone fracture	PLXNA4 COBL PRKCE	2.23e-03	112	68	3	EFO_0003931

Protein segments in the cluster

Peptide	Gene	Start	Entry
FIKPKQLEGLPPGTK	ZNF280D	501	Q6N043
IPPKKTGKIPRIFLK	ATAD5	331	Q96QE3
KILQKSPLPPGNVKK	RNPEP	541	Q9H4A4
RKKGLDIPAKKPPGL	ANKRD11	1631	Q6UB99
LKLPKPPKKVGVFLD	BTN3A1	451	O00481
ALLFPEKPKPKPQLL	DEPDC1B	496	Q8WUY9
AVGPKVALKPPIQRK	ADAM8	801	P78325
IPKALQKALPFKNKP	BMS1	1166	Q14692
PLPKGGKRQKKVPVQ	ERCC6	406	Q03468
GKNFIPPKKPKTFLQ	ATP2B1	86	P20020
AKLFPGRPPVKKLLE	QSOX2	361	Q6ZRP7
PLPKGGKRQKKVPVQ	ERCC6	406	P0DP91
LTPPVKHFQLKRKPK	NELFA	156	Q9H3P2
PLLKKPYQPRIKISK	ITIH5	661	Q86UX2
LEQKKIKPPFKPRIK	PRKCE	676	Q02156
IVPHVGKKPVKIDPK	FSIP2	6521	Q5CZC0
PLIGKLPATRKPNKK	GPATCH8	1146	Q9UKJ3
QFPKAKLKPGAPLKP	FLNB	236	O75369
KLKPGAPLKPKLNPK	FLNB	241	O75369
GAIKKKKPAFLVPIV	PLGRKT	71	Q9HBL7
KPGTPIILKGKNLIP	PLXNA4	1156	Q9HCM2
KVGFLKPVGPKPINL	FYB1	106	O15117
IVNPPKDLKKPRGKK	GLYR1	26	Q49A26
KLPVLPPKLTLFNAK	OGN	181	P20774
KPGIFPKTVKNKPIP	LARP7	196	Q4G0J3
GKRAIPVPNKLGLKK	GTSE1	281	Q9NYZ3
GPFLVEKQKTLPKLP	NHLRC2	581	Q8NBF2
QPSPAKPQLKLKIKL	INO80B	61	Q9C086
KGLLPKPKKTPFLVS	SLC25A31	211	Q9H0C2
KLKFIIPSPKRPVKL	APOB	921	P04114
PQKLLLPKPKVALVK	ATMIN	291	O43313
KAKLKPGAPLRPKLN	FLNA	266	P21333
PIKAKPKQPFLKRGE	CENPJ	366	Q9HC77
PSIFGPKKKFKPVVQ	COBL	1086	O75128
KPQGLDKEPKLPPKL	ANKMY2	146	Q8IV38
KGKPFQLVLPAEVKP	DNAAF11	346	Q86X45
LGPGVKAKKPIQTKF	FMNL1	626	O95466
PKPKTKRFQLPLDKG	KMT2A	3536	Q03164
ELKKPPPNLFKIIQK	CAPN2	216	P17655
PKPKKVAPLKIKLGG	CHD4	286	Q14839
IKPKLKLNPLTKVPI	EFCAB3	6	Q8N7B9
IKPGLVKKINRLPTP	LIMCH1	61	Q9UPQ0
PKPVKPGQVKVFRAL	OSTF1	6	Q92882
KRKKILPNGPKAPVT	HMG20B	61	Q9P0W2
KKPIIPKEFGGKVPT	REXO1	801	Q8N1G1
IIAQLPPPIKKKKFG	UTP4	671	Q969X6
VSNLKPVPLIGPKLK	SCCPDH	216	Q8NBX0
VLKFPKQQLPPKKKR	TAF1L	1361	Q8IZX4
LVLKFPKQQLPPKKK	TAF1	1341	P21675
LPKLPKPYITINNLK	PSG8	236	Q9UQ74
PPKPEFGKLKKFSQP	PRAM1	36	Q96QH2
LLHFPKVFPKNQKPK	ST3GAL6	241	Q9Y274
QFFKGLPKVLPKLPK	SCYL2	351	Q6P3W7
KKHPPPVETKKILGL	CCT8L2	541	Q96SF2
LKKVQKPLLQAPFLP	RHOBTB1	221	O94844
PGQAAPLLPKKGILK	NUAK2	436	Q9H093
PLLPKKGILKKPRQR	NUAK2	441	Q9H093
PLKPLKIKLSVPKAG	PRR12	1221	Q9ULL5
KGANRKKNLPPKVPI	SLX4	1546	Q8IY92
AAPPAQPLAKKKGVK	BRD2	266	P25440
GTGKKVKVRPPPLKK	CIC	1326	Q96RK0
PGPKKKFKAPQSKAL	ZCWPW1	541	Q9H0M4
KKEPPKPPLNNFKVG	SCML2	161	Q9UQR0
KDPKQRIIPFLPGKI	SH3PXD2B	66	A1X283
PLPKSKGKGKPLQRK	TMEM131	1376	Q92545
PKKVYKPIILQQKPR	ZDBF2	2191	Q9HCK1
FKTKAGVPNKPGIPK	ROS1	1746	P08922
GLLQPPKRPIVFKEK	UBE2Q2L	21	H0YL09
PRPLVKLLPKGVQKE	ZNF200	86	P98182
NKIVIPKKKGPVQPA	TPGS2	256	Q68CL5
APQKKFGPVVAPKPK	ZYX	21	Q15942
FLRKKPIVPEHKKQP	ZC3H12C	401	Q9C0D7
QKKVPQKKVPYAKPI	WDR33	486	Q9C0J8
PKYLKVIPPIKAKEK	WDR87	2596	Q6ZQQ6