Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 HIF1A ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 NFX1 ZNF616 ZFHX3 E4F1 ZNF101 ZNF723 REST ZNF333 PRDM5 ZNF658B YY1 ZNF564 ZNF840P ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	8.75e-27	1459	65	38	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 HIF1A ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 NFX1 ADNP2 ZNF616 ZFHX3 E4F1 ZNF101 ZNF723 REST ZNF333 PRDM5 ZNF658B YY1 ZNF840P ZBTB24 ZFP37 ZNF572 ZNF124	8.39e-25	1412	65	36	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 HIF1A ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF483 ZNF616 ZFHX3 E4F1 ZNF101 ZNF723 REST ZNF333 PRDM5 ZNF658B YY1 ZNF564 ZNF840P ZBTB24 IKZF4 ZNF572 ZNF662	3.47e-24	1244	65	34	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 HIF1A ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF483 ZNF616 ZFHX3 E4F1 ZNF101 ZNF723 REST ZNF333 PRDM5 ZNF658B YY1 ZNF564 ZNF840P ZBTB24 IKZF4 ZNF572 ZNF662	6.96e-24	1271	65	34	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity	HIF1A ZNF382 NFX1 ZFHX3 E4F1 ZNF101 REST PRDM5 YY1 ZBTB24 ZNF572	7.58e-09	326	65	11	GO:0001217
GeneOntologyMolecularFunction	DNA-binding transcription repressor activity, RNA polymerase II-specific	ZNF382 NFX1 ZFHX3 E4F1 ZNF101 REST PRDM5 YY1 ZBTB24 ZNF572	7.97e-08	320	65	10	GO:0001227
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	GFI1B HIF1A ZNF48 ZNF658 E4F1 ZNF101 ZNF658B YY1 ZNF840P	7.95e-05	560	65	9	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	GFI1B HIF1A ZNF48 ZNF658 E4F1 ZNF101 ZNF658B YY1 ZNF840P	8.62e-05	566	65	9	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	GFI1B HIF1A LRP2 E4F1 REST PRDM5 YY1 IKZF4	5.81e-04	582	65	8	GO:0140297
GeneOntologyMolecularFunction	transcription factor binding	GFI1B HIF1A LRP2 E4F1 REST KDM1B PRDM5 YY1 IKZF4	7.09e-04	753	65	9	GO:0008134
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	STAB2 LRP2	1.22e-03	16	65	2	GO:0005041
GeneOntologyMolecularFunction	low-density lipoprotein particle binding	THBS1 STAB2	1.54e-03	18	65	2	GO:0030169
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	STAB2 LRP2	2.11e-03	21	65	2	GO:0030228
GeneOntologyMolecularFunction	K63-linked polyubiquitin modification-dependent protein binding	RNF31 OTUD7B	3.22e-03	26	65	2	GO:0070530
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	GFI1B HIF1A ZNF382 GLI3 MAZ NFX1 ZFHX3 E4F1 ZNF101 REST PRDM5 YY1 ZBTB24 ZNF572 OTUD7B	7.08e-07	1053	65	15	GO:0000122
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	GFI1B HIF1A ZNF658 ZNF382 GLI3 MAZ NFX1 ZFHX3 E4F1 ZNF101 REST PRDM5 YY1 ZBTB24 IKZF4 ZNF572 OTUD7B	1.02e-06	1399	65	17	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	GFI1B HIF1A ZNF658 ZNF382 GLI3 MAZ NFX1 ZFHX3 E4F1 ZNF101 REST PRDM5 YY1 ZBTB24 IKZF4 ZNF572 OTUD7B	1.17e-06	1413	65	17	GO:1902679
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	GFI1B HIF1A ZNF48 ZNF658 GLI3 MAZ ZFHX3 E4F1 REST PRDM5 ZNF658B YY1 ZNF840P IKZF4	8.81e-05	1390	65	14	GO:0045944
GeneOntologyBiologicalProcess	negative regulation of miRNA transcription	HIF1A REST YY1	1.26e-04	31	65	3	GO:1902894
GeneOntologyBiologicalProcess	negative regulation of miRNA metabolic process	HIF1A REST YY1	1.67e-04	34	65	3	GO:2000629
GeneOntologyCellularComponent	nuclear body	HIF1A GLI3 LPXN FAM76A TRIM8 FAM76B PHF7 ZFHX3 E4F1 USPL1 PRDM5 IKZF4	2.24e-05	903	66	12	GO:0016604
Domain	ZINC_FINGER_C2H2_2	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ADNP2 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 ZC3H7B PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	1.36e-33	775	63	36	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ADNP2 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 ZC3H7B PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	1.49e-33	777	63	36	PS00028
Domain	Znf_C2H2-like	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ADNP2 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 ZC3H7B PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	3.52e-33	796	63	36	IPR015880
Domain	Znf_C2H2	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ADNP2 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 ZC3H7B PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	5.25e-33	805	63	36	IPR007087
Domain	ZnF_C2H2	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ADNP2 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 ZC3H7B PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	6.00e-33	808	63	36	SM00355
Domain	-	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	1.44e-32	679	63	34	3.30.160.60
Domain	Znf_C2H2/integrase_DNA-bd	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	3.00e-32	694	63	34	IPR013087
Domain	zf-C2H2	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 MAZ ZNF329 ZNF483 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 REST ZNF333 PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	8.84e-31	693	63	33	PF00096
Domain	zf-C2H2_6	ZNF502 GFI1B ZSCAN5B ZNF320 ZNF48 ZNF658 ZNF792 ZNF382 ZNF329 ZNF483 ZNF200 ZNF616 E4F1 ZNF333 PRDM5 ZNF564 ZBTB24 ZFP37 ZNF572	3.53e-19	314	63	19	PF13912
Domain	KRAB	ZNF7 ZNF430 ZNF708 ZNF610 ZNF320 ZNF37A ZNF658 ZNF792 ZNF382 ZNF483 ZNF616 ZNF101 ZNF333 ZNF564 ZFP37 ZNF124 ZNF662	1.98e-15	358	63	17	PS50805
Domain	KRAB	ZNF7 ZNF430 ZNF708 ZNF610 ZNF320 ZNF37A ZNF658 ZNF792 ZNF382 ZNF483 ZNF616 ZNF101 ZNF333 ZNF564 ZFP37 ZNF124 ZNF662	3.27e-15	369	63	17	SM00349
Domain	KRAB	ZNF7 ZNF430 ZNF708 ZNF610 ZNF320 ZNF37A ZNF658 ZNF792 ZNF382 ZNF483 ZNF616 ZNF101 ZNF333 ZNF564 ZFP37 ZNF124 ZNF662	3.42e-15	370	63	17	IPR001909
Domain	KRAB	ZNF7 ZNF430 ZNF708 ZNF610 ZNF320 ZNF37A ZNF658 ZNF792 ZNF382 ZNF483 ZNF616 ZNF101 ZNF333 ZNF564 ZFP37 ZNF124	3.85e-14	358	63	16	PF01352
Domain	FAM76	FAM76A FAM76B	1.12e-05	2	63	2	IPR032017
Domain	FAM76	FAM76A FAM76B	1.12e-05	2	63	2	PF16046
Domain	Growth_fac_rcpt_	EPHB6 ELAPOR2 STAB2 LRP2	1.90e-03	156	63	4	IPR009030
Domain	C2H2_Znf_fam	ZSCAN5B REST	2.95e-03	24	63	2	IPR027775
Domain	Ephrin_rec_like	EPHB6 ELAPOR2	3.20e-03	25	63	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB6 ELAPOR2	3.20e-03	25	63	2	IPR011641
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF430 ZNF708 THBS1 ZNF138 ZNF610 ZNF320 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 ZNF483 ZNF200 ZNF616 ZFHX3 ZNF101 REST ZNF333 YY1 ZNF564 ZFP37 ZNF124 ZNF662	4.10e-13	1387	42	23	M734
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ZNF610 ZNF382 ZNF616 ZNF101	2.23e-05	56	42	4	MM17236
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_KRAB_ZFP_PROTEINS	ZNF708 ZNF610 ZNF320 ZNF382	2.81e-04	107	42	4	M48260
Pubmed	A census of human transcription factors: function, expression and evolution.	ZNF7 GFI1B ZNF708 HIF1A ZNF37A GLI3 MAZ NFX1 ADNP2 ZNF200 ZFHX3 E4F1 REST PRDM5 YY1 ZBTB24	1.32e-11	908	67	16	19274049
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF7 GFI1B ZSCAN5B ZNF610 HIF1A ZNF48 GLI3 ZNF616 ZFHX3 REST FBLIM1 PRDM5 YY1 ZBTB24 ZFP37	3.07e-11	808	67	15	20412781
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF7 ZNF430 ZNF708 ZNF320 ZNF792 ZNF101 ZNF564 ZNF124	2.31e-09	181	67	8	37372979
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	HIF1A RNF31 GLI3 LPXN NFX1 TRIM8 ZFHX3 E4F1 ZNF101 REST FBLIM1 IKZF4	1.01e-08	709	67	12	22988430
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF7 ZNF610 ZNF616 ZNF101	2.50e-06	49	67	4	9630514
Pubmed	Yin yang 1 directly regulates the transcription of RE-1 silencing transcription factor.	REST YY1	3.66e-06	2	67	2	18092359
Pubmed	Renal Protection Mediated by Hypoxia Inducible Factor-1α Depends on Proangiogenesis Function of miR-21 by Targeting Thrombospondin 1.	THBS1 HIF1A	3.66e-06	2	67	2	28737660
Pubmed	Hypoxia stimulates the autocrine regulation of migration of vascular smooth muscle cells via HIF-1alpha-dependent expression of thrombospondin-1.	THBS1 HIF1A	3.66e-06	2	67	2	18384112
Pubmed	Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.	HIF1A OTUD7B	3.66e-06	2	67	2	25355043
Pubmed	The transcription factor ZFHX3 is crucial for the angiogenic function of hypoxia-inducible factor 1α in liver cancer cells.	HIF1A ZFHX3	3.66e-06	2	67	2	32277050
Pubmed	REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia.	HIF1A REST	3.66e-06	2	67	2	26647819
Pubmed	Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes.	HIF1A YY1	3.66e-06	2	67	2	20105288
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	ZNF502 HIF1A GLI3 NFX1 ZNF200 E4F1 REST PRDM5 YY1 ZBTB24	6.68e-06	877	67	10	20211142
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF610 RNF31 GLI3 MAZ ADNP2 LRP2 ZFHX3 KDM1B REV3L PRDM5 YY1	8.77e-06	1116	67	11	31753913
Pubmed	Transcription factor YY1 contributes to tumor growth by stabilizing hypoxia factor HIF-1α in a p53-independent manner.	HIF1A YY1	1.10e-05	3	67	2	23328582
Pubmed	Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors.	THBS1 HIF1A	1.10e-05	3	67	2	20470445
Pubmed	Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment.	FAM76A FAM76B	1.10e-05	3	67	2	19266028
Pubmed	The Role of PTEN in Chemoresistance Mediated by the HIF-1α/YY1 Axis in Pediatric Acute Lymphoblastic Leukemia.	HIF1A YY1	1.10e-05	3	67	2	39063014
Pubmed	Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development.	HIF1A LRP2 YY1	1.52e-05	25	67	3	23554936
Pubmed	Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.	THBS1 LRP2	2.19e-05	4	67	2	7775583
Pubmed	MIR448 antagomir reduces arrhythmic risk after myocardial infarction by upregulating the cardiac sodium channel.	HIF1A REST	2.19e-05	4	67	2	33108349
Pubmed	Multiple genes encoding zinc finger domains are expressed in human T cells.	ZNF7 ZNF708 ZNF37A	2.96e-05	31	67	3	2288909
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZNF7 EPHB6 THBS1 ZNF329 TRIM8 ADNP2 NAV3 LRP2 REV3L USPL1 ZNF662	3.23e-05	1285	67	11	35914814
Pubmed	TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.	THBS1 HIF1A	3.64e-05	5	67	2	28555642
Pubmed	Decorin antagonizes the angiogenic network: concurrent inhibition of Met, hypoxia inducible factor 1α, vascular endothelial growth factor A, and induction of thrombospondin-1 and TIMP3.	THBS1 HIF1A	3.64e-05	5	67	2	22194599
Pubmed	Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary disease.	THBS1 HIF1A	5.46e-05	6	67	2	18035072
Pubmed	HIF-2α-mediated induction of pulmonary thrombospondin-1 contributes to hypoxia-driven vascular remodelling and vasoconstriction.	THBS1 HIF1A	5.46e-05	6	67	2	26503986
Pubmed	Aurora kinase A regulates Survivin stability through targeting FBXL7 in gastric cancer drug resistance and prognosis.	ZFHX3 REST YY1	5.49e-05	38	67	3	28218735
Pubmed	Hypoxia-inducible factor/MAZ-dependent induction of caveolin-1 regulates colon permeability through suppression of occludin, leading to hypoxia-induced inflammation.	HIF1A MAZ	7.63e-05	7	67	2	24891620
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ZNF502 HIF1A ZNF320 ZNF658 GLI3 MAZ ZNF329 FAM76B YY1 ZFP37	9.76e-05	1203	67	10	29180619
Pubmed	Molecular characterization of seizure-related genes isolated by differential screening.	DGCR2 REV3L	1.30e-04	9	67	2	8645260
Pubmed	Gene mapping of SEZ group genes and determination of pentylenetetrazol susceptible quantitative trait loci in the mouse chromosome.	DGCR2 REV3L	1.63e-04	10	67	2	10700579
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	DHX16 MAZ ZNF483 ADNP2 KDM1B YY1 ZBTB24	1.69e-04	608	67	7	36089195
Pubmed	Polydactyly and ectopic ZPA formation in Alx-4 mutant mice.	THBS1 GLI3	1.99e-04	11	67	2	9374397
Pubmed	Ablation of cholesterol biosynthesis in neural stem cells increases their VEGF expression and angiogenesis but causes neuron apoptosis.	HIF1A LRP2	1.99e-04	11	67	2	19416849
Pubmed	Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.	ZNF610 ZNF616 ZFP37	2.16e-04	60	67	3	18023262
Pubmed	Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects.	HIF1A REST	2.38e-04	12	67	2	21072209
Pubmed	Genome-wide and candidate gene association study of cigarette smoking behaviors.	ZNF138 NAV3	2.81e-04	13	67	2	19247474
Pubmed	Twenty-seven nonoverlapping zinc finger cDNAs from human T cells map to nine different chromosomes with apparent clustering.	ZNF708 ZNF37A	3.28e-04	14	67	2	2014798
Pubmed	LRP2 is an auxiliary SHH receptor required to condition the forebrain ventral midline for inductive signals.	GLI3 LRP2	3.78e-04	15	67	2	22340494
Pubmed	Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.	ADNP2 REST REV3L	4.02e-04	74	67	3	29795351
Pubmed	Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome.	GLI3 LRP2	4.31e-04	16	67	2	15005800
Pubmed	The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.	KDM1B YY1	4.31e-04	16	67	2	20805357
Pubmed	The ciliary protein Ftm is required for ventricular wall and septal development.	HIF1A GLI3	6.12e-04	19	67	2	23469020
Pubmed	The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex.	TRIM8 PHF7	7.50e-04	21	67	2	25590999
Pubmed	High-throughput screen for genes predominantly expressed in the ICM of mouse blastocysts by whole mount in situ hybridization.	ZNF48 ADNP2 REST	8.08e-04	94	67	3	16325481
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	ZNF7 ZNF48	8.24e-04	22	67	2	1946370
Pubmed	The interactome of KRAB zinc finger proteins reveals the evolutionary history of their functional diversification.	ZNF138 ZNF333	8.24e-04	22	67	2	31403225
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	ZNF138 ZNF320 ZNF792 ADNP2	8.31e-04	217	67	4	34048709
Pubmed	A whole genome screen for HIV restriction factors.	ZNF430 ZNF658 ZNF124	1.21e-03	108	67	3	22082156
Pubmed	Identification of differentially expressed genes in mouse spermatogenesis.	ZNF610 ZNF616	1.24e-03	27	67	2	14581517
Pubmed	Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.	HIF1A LRP2	1.34e-03	28	67	2	28847650
Pubmed	Specification of jaw identity by the Hand2 transcription factor.	HIF1A ZFHX3	1.34e-03	28	67	2	27329940
Pubmed	22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development.	DGCR2 GLI3	1.44e-03	29	67	2	23077214
Pubmed	Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice.	HIF1A ITSN2	1.64e-03	31	67	2	19666558
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	LPXN ZFHX3 FBLIM1 IKZF4	1.69e-03	263	67	4	20932939
Interaction	LTBP2 interactions	ZNF430 ZNF708 ZNF320 ZNF483 E4F1 ZNF101 ZNF564 ZBTB24	2.97e-10	85	65	8	int:LTBP2
Interaction	KRTAP10-7 interactions	ZNF138 ZNF320 ZNF792 ZNF329 FAM76B E4F1 ZNF101 ZNF564 ZBTB24 ZNF572 ZNF124	2.27e-09	293	65	11	int:KRTAP10-7
Interaction	TRIM28 interactions	DHX16 ZNF7 ZNF430 ZNF708 HIF1A ZNF320 RNF31 ZNF37A ZNF658 ZNF792 ZNF382 ZNF483 NFX1 ZNF616 ZNF101 REST ZNF333 ZC3H7B ZNF564 ZNF124	1.97e-08	1474	65	20	int:TRIM28
Interaction	KRTAP10-5 interactions	ZNF320 ZNF792 ZNF329 FAM76B YY1 ZBTB24 ZNF572 ZNF124	4.55e-08	160	65	8	int:KRTAP10-5
Interaction	KRTAP10-1 interactions	ZNF138 ZNF329 FAM76B ZNF101 ZBTB24 ZNF572 ZNF124	6.10e-07	153	65	7	int:KRTAP10-1
Interaction	KRTAP10-9 interactions	ZNF792 MAZ FAM76B YY1 ZNF564 ZBTB24 ZNF572 ZNF124	1.04e-06	241	65	8	int:KRTAP10-9
Interaction	KRTAP10-3 interactions	ZNF138 ZNF792 FAM76B ZNF101 ZNF564 ZBTB24 ZNF572 ZNF124	4.58e-06	294	65	8	int:KRTAP10-3
Interaction	ZNF652 interactions	ZNF382 GLI3 PRDM5 ZFP37	4.79e-06	35	65	4	int:ZNF652
Interaction	ZFP28 interactions	ZNF382 GLI3 PRDM5 ZFP37	6.01e-06	37	65	4	int:ZFP28
Interaction	TRIM41 interactions	ZNF138 ZNF48 ZNF792 ZNF329 PHF7 ZNF564 ZBTB24	7.46e-06	223	65	7	int:TRIM41
Interaction	EHMT2 interactions	GFI1B MAZ ADNP2 E4F1 REST KDM1B PRDM5 YY1	7.59e-06	315	65	8	int:EHMT2
Interaction	NOTCH2 interactions	ZNF7 ZNF430 ZNF708 ZNF320 ZNF48 MAZ ZNF483 E4F1 ZBTB24	8.21e-06	423	65	9	int:NOTCH2
Interaction	ZFP62 interactions	ZNF48 ZNF382 GLI3 PRDM5 ZFP37	1.69e-05	99	65	5	int:ZFP62
Interaction	CCDC136 interactions	GFI1B ZNF329 ZNF564 ZBTB24 ZNF572 ZNF124	1.75e-05	169	65	6	int:CCDC136
Interaction	ZFP37 interactions	ZNF382 GLI3 PRDM5 ZFP37	1.87e-05	49	65	4	int:ZFP37
Interaction	GZF1 interactions	ZNF382 GLI3 E4F1 PRDM5 ZFP37	2.05e-05	103	65	5	int:GZF1
Interaction	PRDM4 interactions	ZNF382 GLI3 PRDM5 ZFP37	2.37e-05	52	65	4	int:PRDM4
Interaction	ZNF667 interactions	ZNF382 GLI3 PRDM5 ZFP37	2.56e-05	53	65	4	int:ZNF667
Interaction	ZNF473 interactions	ZNF792 ZNF382 GLI3 ZFP37	3.19e-05	56	65	4	int:ZNF473
Interaction	FAM76A interactions	FAM76A FAM76B YY1	4.09e-05	21	65	3	int:FAM76A
Interaction	ZNF287 interactions	ZNF382 GLI3 PRDM5 ZFP37	4.20e-05	60	65	4	int:ZNF287
Interaction	KRTAP10-8 interactions	ZNF138 ZNF792 FAM76B ZNF101 YY1 ZBTB24 ZNF572 ZNF124	4.29e-05	401	65	8	int:KRTAP10-8
Interaction	CTCFL interactions	ZNF48 ZNF382 GLI3 ZFP37	4.78e-05	62	65	4	int:CTCFL
Interaction	TRAF1 interactions	ZNF502 GFI1B RNF31 ZNF564 ZNF572 ZNF124 ZNF662	5.35e-05	303	65	7	int:TRAF1
Interaction	GOLGA6L9 interactions	ZNF48 ZNF792 ZNF329 ZFHX3 ZBTB24 ZNF124	6.90e-05	216	65	6	int:GOLGA6L9
Interaction	MDFI interactions	ZNF138 ZNF101 YY1 ZNF564 ZBTB24 ZNF572 ZNF124 ZNF662	7.01e-05	430	65	8	int:MDFI
Interaction	KRT40 interactions	ZNF138 ZNF792 ZNF329 ZFHX3 ZNF101 ZNF564 ZBTB24 ZNF124	7.48e-05	434	65	8	int:KRT40
Interaction	ZSCAN10 interactions	ZNF382 GLI3 ZFP37	7.90e-05	26	65	3	int:ZSCAN10
Interaction	ZNF423 interactions	ZNF382 GLI3 PRDM5 ZFP37	9.08e-05	73	65	4	int:ZNF423
Interaction	ZFAT interactions	ZNF382 PRDM5 ZFP37	9.90e-05	28	65	3	int:ZFAT
Interaction	TNFRSF1B interactions	RNF31 NFX1 FAM76B ZNF101 ARMCX5	1.08e-04	146	65	5	int:TNFRSF1B
Interaction	ZNF710 interactions	ZNF382 PRDM5 ZFP37	1.22e-04	30	65	3	int:ZNF710
Interaction	ZFP3 interactions	ZNF382 GLI3 ZFP37	1.22e-04	30	65	3	int:ZFP3
Interaction	ZBTB8A interactions	ZNF138 ZNF329 ZBTB24 ZNF572	1.36e-04	81	65	4	int:ZBTB8A
Interaction	ZNF382 interactions	ZNF382 GLI3 ZFP37	1.63e-04	33	65	3	int:ZNF382
Interaction	ZNF513 interactions	ZNF382 GLI3 ZFP37	1.78e-04	34	65	3	int:ZNF513
Interaction	MTUS2 interactions	ZNF48 ZNF792 ZNF329 ZFHX3 ZNF564 ZNF572 ZNF124	1.85e-04	370	65	7	int:MTUS2
Interaction	GOLGA8A interactions	ZNF320 ITSN2 ZNF483	1.95e-04	35	65	3	int:GOLGA8A
Interaction	MID2 interactions	GFI1B HIF1A ZNF792 ZNF564 ZBTB24 ZNF124	2.19e-04	267	65	6	int:MID2
Interaction	ZNF24 interactions	RNF31 ZNF382 ZNF483 YY1 ZFP37	2.46e-04	174	65	5	int:ZNF24
Interaction	KRTAP2-3 interactions	ZNF792 YY1 ZNF564 ZBTB24	2.52e-04	95	65	4	int:KRTAP2-3
Interaction	ZNF467 interactions	ZNF320 ZNF48 ZNF483 ZNF101 ZBTB24	2.81e-04	179	65	5	int:ZNF467
Interaction	HRC interactions	ZNF430 ZNF101	2.83e-04	8	65	2	int:HRC
Interaction	GLI2 interactions	GLI3 LPXN PRDM5 ZFP37	2.95e-04	99	65	4	int:GLI2
Interaction	KRTAP2-4 interactions	ZNF792 YY1 ZNF564 ZBTB24	3.18e-04	101	65	4	int:KRTAP2-4
Interaction	TRIM39 interactions	EPHB6 ZNF658 TRIM8 ZNF333	4.11e-04	108	65	4	int:TRIM39
Interaction	MTSS2 interactions	TRIM8 YY1 OTUD7B	5.31e-04	49	65	3	int:MTSS2
Cytoband	19q13.41	ZNF610 ZNF320 ZNF616	2.09e-04	78	67	3	19q13.41
Cytoband	19p12	ZNF430 ZNF708 ZNF723	3.19e-04	90	67	3	19p12
Cytoband	6q21	AK9 REV3L ZBTB24	3.85e-04	96	67	3	6q21
Cytoband	Ensembl 112 genes in cytogenetic band chr6q21	AK9 REV3L ZBTB24	7.56e-04	121	67	3	chr6q21
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF430 ZNF708 ZNF723	7.75e-04	122	67	3	chr19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZSCAN5B ZNF610 ZNF320 ZNF792 ZNF382 ZNF329 ZNF616	1.75e-03	1192	67	7	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF502 ZNF7 GFI1B ZNF430 ZNF708 ZSCAN5B ZNF138 ZNF610 ZNF320 ZNF48 ZNF37A ZNF658 ZNF792 ZNF382 GLI3 MAZ ZNF329 ZNF483 ADNP2 ZNF200 ZNF616 ZFHX3 E4F1 ZNF101 ZNF333 PRDM5 YY1 ZNF564 ZBTB24 ZFP37 IKZF4 ZNF572 ZNF124 ZNF662	4.12e-34	718	55	34	28
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ADNP2 ZFHX3	9.30e-04	15	55	2	529
ToppCell	3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ELAPOR2 STAB2 ZNF37A ZFHX3 ZNF662	5.86e-06	173	66	5	85083b9ce20351dd69aa2327ad087b848b4307ff
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	TRIM8 REST REV3L YY1 C17orf58	1.16e-05	199	66	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
Computational	Genes in the cancer module 197.	HIF1A MAZ ADNP2 YY1 ZBTB24 ZNF124	5.76e-06	174	29	6	MODULE_197
Computational	Genes in the cancer module 98.	HIF1A GLI3 MAZ ADNP2 YY1 ZBTB24 ZNF124	6.43e-05	393	29	7	MODULE_98
Disease	attempted suicide	ELAPOR2 NAV3 LRP2 FAM76B KCNMB3	3.70e-05	178	62	5	EFO_0004321
Disease	cortical surface area measurement	DHX16 THBS1 GLI3 TRIM8 NAV3 FAM76B ZFHX3 REST PRDM5 C17orf58	4.63e-04	1345	62	10	EFO_0010736
Disease	smoking behavior	TRIM8 NAV3 ZFHX3 REV3L IKZF4	7.55e-04	341	62	5	EFO_0004318
Disease	Vitiligo	FAM76B ZC3H7B IKZF4	1.27e-03	101	62	3	EFO_0004208
Disease	cortical surface area measurement, neuroimaging measurement	THBS1 NAV3 ZFHX3 C17orf58	1.34e-03	227	62	4	EFO_0004346, EFO_0010736
Disease	caudate nucleus volume	ZFHX3 YY1	1.82e-03	30	62	2	EFO_0004830
Disease	Prostatic Neoplasms	HIF1A STAB2 RNF31 ITSN2 LRP2 ZFHX3	1.84e-03	616	62	6	C0033578
Disease	Malignant neoplasm of prostate	HIF1A STAB2 RNF31 ITSN2 LRP2 ZFHX3	1.84e-03	616	62	6	C0376358
Disease	diabetic retinopathy (biomarker_via_orthology)	THBS1 HIF1A	4.06e-03	45	62	2	DOID:8947 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PSLKPKYAKCDQCGN	DUS1L	386	Q6P1R4
DPGFCKQKSYNPRTG	DHX16	691	O60231
TGQCYKQFDPFCPLK	CC2D2B	1231	Q6DHV5
YGPNPKACHCKSRGF	ARMCX5	291	Q6P1M9
PPDKYYCKKCNANAS	ADNP2	211	Q6IQ32
LKACKPNGKSNPYCE	ITSN2	1581	Q9NZM3
PYQCPYCEKGFSKND	PRDM5	516	Q9NQX1
PPTQTKCKQPNCSFY	OTUD7B	796	Q6GQQ9
PRQFNCPVCDYAASK	REST	386	Q13127
EQPCKAPQYGNCLNR	GLI3	1246	P10071
RPYPCQFCGKRFHQK	GFI1B	246	Q5VTD9
YDTNSNQPQCGYKKP	HIF1A	201	Q16665
SCNKPCPEFKPGSRY	C17orf58	266	Q2M2W7
DIFNGFLNCKYNKCP	NAV3	2136	Q8IVL0
PNTYTCFCGKVKNPE	NFX1	416	Q12986
PYQCPVCQQRFKRKD	MAZ	306	P56270
KYGPPQTCEQCKQQC	FAM76B	96	Q5HYJ3
NDKTYCQPCFNKLFP	LPXN	371	O60711
QPYATNPCKDNNGGC	LRP2	656	P98164
KPGSFNCQVCPRNTY	ELAPOR2	301	A8MWY0
EKKDCPPCNPGFYNN	ELAPOR2	391	A8MWY0
PFYQPNECGKALCVR	KDM1B	271	Q8NB78
CERPQGCQQYRKDPK	DGCR2	311	P98153
QSFYQKDGRPLCEPC	FBLIM1	221	Q8WUP2
NPKCFYTPKCHQDRN	KCNMB3	151	Q9NPA1
RPFACAQCGKAFPKA	E4F1	461	Q66K89
GEKPFKCPFCNYACR	IKZF4	211	Q9H2S9
KSRFPKCAELQGYCP	AK9	1716	Q5TCS8
FFKCPQCNNRKEFPQ	PHF7	201	Q9BWX1
CQPGYQPARGDKACQ	EPHB6	301	O15197
GPPYSCEQCKQQCAF	FAM76A	96	Q8TAV0
KPYQCPECGKNFSRS	ZNF572	326	Q7Z3I7
RPYKCNACGKVFNQN	ZNF610	426	Q8N9Z0
CYNAFYAKNKCPEPN	RNF31	901	Q96EP0
RQKPYGCNQCGKSFC	ZNF37A	491	P17032
PYKCQECGKAFDRPS	ZNF564	196	Q8TBZ8
YHCKKDNCPNLPNSG	THBS1	711	P07996
RQDHNYCSPTKKNPC	USPL1	1021	Q5W0Q7
QGPKAQDKPYICTDC	ZNF48	266	Q96MX3
PFGDNCFKCNEYSKP	ZNF320	491	A2RRD8
KPYKCNQCGNSFSQR	ZNF616	631	Q08AN1
PYKCEQCGKVFKQSP	ZNF138	221	P52744
PCRSFGNNKYPQNSD	REV3L	436	O60673
RPYVCPFDGCNKKFA	YY1	381	P25490
PYKCPTCQKAFRQLG	ZSCAN5B	466	A6NJL1
KPYKCEECGKAFNQP	ZNF723	311	P0DPD5
KPYECGECGKRFNNN	ZNF840P	471	A6NDX5
QFCSDPNKYGPRCNK	STAB2	776	Q8WWQ8
KPYSCSQCGKNFRQN	ZNF200	306	P98182
AQKPYVCNNCGKGFR	ZNF124	286	Q15973
TREKPYECNQCGKPF	ZNF333	501	Q96JL9
GKKPFSCPECNLQFA	ZBTB24	486	O43167
KPCDNNGCGRSYKSP	ZNF658	466	Q5TYW1
PYKCEECGKAFNQSP	ZNF708	531	P17019
PYKCEECGKAFNRSP	ZNF430	456	Q9H8G1
RPYECNKCGKTFNYP	ZNF101	336	Q8IZC7
PYKCNRCGKAFNQNT	ZNF502	266	Q8TBZ5
PYECSECGKAFNQRP	ZNF792	561	Q3KQV3
GEKPYKCNQCEKAFP	ZNF483	631	Q8TF39
EKPYVCNQCGKAFRQ	ZNF382	321	Q96SR6
RCPECNQAYNQKPGL	TRIM8	51	Q9BZR9
PQACVKPYECNQCGK	ZFP37	286	Q9Y6Q3
TPYQCPECGKSFKQN	ZNF329	481	Q86UD4
RPYKCNECGKAFSQN	ZNF7	551	P17097
RPYKCNDCGKAFSQN	ZNF662	386	Q6ZS27
PDNKPFKCNTCNVAY	ZFHX3	1591	Q15911
FKQACQLCYPKTGPR	ZC3H7B	421	Q9UGR2
KPCDNNGCGRSYKSP	ZNF658B	226	Q4V348