Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR52B4 ADORA3 VN1R5 TAS2R1 TAS2R9 OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR TAS2R50 PTGER2 F2R OR7G3 ADCYAP1R1 OR4F6

1.29e-078848417GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR52B4 ADORA3 VN1R5 TAS2R1 TAS2R9 PTPRD OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR TAS2R50 PTGER2 F2R OR7G3 RYK ADCYAP1R1 OR4F6

2.58e-0613538419GO:0004888
GeneOntologyMolecularFunctiontransporter activity

CACNA1D ORAI1 ATP2C1 ABCA6 SCN2A TRPC5 ATP6V0A4 TCIRG1 DISP2 KCNK6 OCA2 PANX2 ATP9A CYB561A3 SLC30A1 SLC30A4 KCNH3 SLC23A3

5.41e-0612898418GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1D ORAI1 ATP2C1 ABCA6 SCN2A TRPC5 ATP6V0A4 TCIRG1 DISP2 KCNK6 OCA2 PANX2 CYB561A3 SLC30A1 SLC30A4 KCNH3 SLC23A3

6.88e-0611808417GO:0022857
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 TCIRG1 KCNK6 SLC30A1 SLC30A4 KCNH3

6.22e-056278411GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 TCIRG1 KCNK6 OCA2 SLC30A1 SLC30A4 KCNH3

7.55e-057588412GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 TCIRG1 KCNK6 SLC30A1 SLC30A4 KCNH3

1.04e-046648411GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 TCIRG1 KCNK6 OCA2 SLC30A1 SLC30A4 KCNH3

1.16e-047938412GO:0015075
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 KCNK6 SLC30A1 SLC30A4 KCNH3

1.46e-04465849GO:0046873
GeneOntologyMolecularFunctionbitter taste receptor activity

TAS2R1 TAS2R9 TAS2R50

1.95e-0427843GO:0033038
GeneOntologyMolecularFunctiontaste receptor activity

TAS2R1 TAS2R9 TAS2R50

3.58e-0433843GO:0008527
GeneOntologyMolecularFunctiontransition metal ion transmembrane transporter activity

ATP2C1 SLC30A1 SLC30A4

8.40e-0444843GO:0046915
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP2C1 ABCA6 ATP6V0A4 TCIRG1 CYB561A3

9.30e-04178845GO:0015399
GeneOntologyMolecularFunctionarachidonate-CoA ligase activity

ACSL1 ACSL6

9.38e-0411842GO:0047676
GeneOntologyMolecularFunctionprostaglandin receptor activity

PTGDR PTGER2

9.38e-0411842GO:0004955
GeneOntologyMolecularFunctionstore-operated calcium channel activity

ORAI1 TRPC5

1.12e-0312842GO:0015279
GeneOntologyMolecularFunctionprostanoid receptor activity

PTGDR PTGER2

1.12e-0312842GO:0004954
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP2C1 ABCA6 ATP6V0A4 TCIRG1

1.16e-03109844GO:0042626
GeneOntologyMolecularFunctionCCR6 chemokine receptor binding

DEFB130A DEFB130B

1.32e-0313842GO:0031731
GeneOntologyMolecularFunctionchannel activity

CACNA1D ORAI1 SCN2A TRPC5 KCNK6 OCA2 PANX2 KCNH3

1.64e-03525848GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1D ORAI1 SCN2A TRPC5 KCNK6 OCA2 PANX2 KCNH3

1.66e-03526848GO:0022803
GeneOntologyMolecularFunctionlong-chain fatty acid-CoA ligase activity

ACSL1 ACSL6

1.77e-0315842GO:0004467
GeneOntologyMolecularFunctionicosanoid receptor activity

PTGDR PTGER2

2.02e-0316842GO:0004953
GeneOntologyMolecularFunctionolfactory receptor activity

OR52B4 OR5AU1 OR4D10 OR6C70 OR6C6 OR7G3 OR4F6

2.26e-03431847GO:0004984
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP2C1 ATP6V0A4 TCIRG1

2.27e-0362843GO:0019829
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1D ORAI1 SCN2A TRPC5 KCNK6 OCA2 KCNH3

3.20e-03459847GO:0005216
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1D ORAI1 SCN2A TRPC5 KCNK6 KCNH3

3.25e-03343846GO:0005261
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1D ORAI1 ATP2C1 TRPC5

3.80e-03151844GO:0015085
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP2C1 ABCA6 ATP6V0A4 TCIRG1 CYB561A3 SLC30A1 SLC30A4

3.95e-03477847GO:0022804
GeneOntologyMolecularFunctionATPase activity, coupled to transmembrane movement of ions, rotational mechanism

ATP6V0A4 TCIRG1

4.54e-0324842GO:0044769
GeneOntologyMolecularFunctionproton-transporting ATPase activity, rotational mechanism

ATP6V0A4 TCIRG1

4.54e-0324842GO:0046961
GeneOntologyMolecularFunctionATPase-coupled ion transmembrane transporter activity

ATP6V0A4 TCIRG1

4.54e-0324842GO:0042625
GeneOntologyMolecularFunctionzinc ion transmembrane transporter activity

SLC30A1 SLC30A4

4.54e-0324842GO:0005385
GeneOntologyMolecularFunctionfatty acid ligase activity

ACSL1 ACSL6

5.32e-0326842GO:0015645
GeneOntologyMolecularFunctionCoA-ligase activity

ACSL1 ACSL6

5.73e-0327842GO:0016405
GeneOntologyBiologicalProcessbleb assembly

PMP22 EMP1 EMP2 EMP3

1.87e-0713854GO:0032060
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

CACNA1D OR52B4 ADORA3 VN1R5 ORAI1 TAS2R1 TAS2R9 OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR TAS2R50 PTGER2 F2R OR7G3 ADCY6 ADCYAP1R1 OR4F6

7.07e-0713958520GO:0007186
GeneOntologyBiologicalProcesssensory perception

CACNA1D OR52B4 VN1R5 TAS2R1 TAS2R9 PDE6B OR5AU1 OR4D10 OR6C70 ATP6V0A4 AOC2 OR6C6 TAS2R50 F2R OR7G3 OR4F6

6.74e-0610728516GO:0007600
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 GAS6 TCIRG1 KCNK6 OCA2 PANX2 SLC30A1 F2R SLC30A4 ADCYAP1R1 KCNH3

1.10e-0511158516GO:0034220
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR52B4 VN1R5 TAS2R1 TAS2R9 OR5AU1 OR4D10 OR6C70 OR6C6 TAS2R50 OR7G3 OR4F6

1.49e-055478511GO:0007606
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 GAS6 TCIRG1 KCNK6 OCA2 SLC30A1 F2R SLC30A4 ADCYAP1R1 KCNH3

1.57e-0510178515GO:0098660
GeneOntologyBiologicalProcessregulation of glomerular filtration

GAS6 EMP2 F2R

1.87e-0513853GO:0003093
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 GAS6 TCIRG1 KCNK6 SLC30A1 F2R SLC30A4 ADCYAP1R1 KCNH3

2.27e-059228514GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 GAS6 TCIRG1 KCNK6 SLC30A1 F2R SLC30A4 ADCYAP1R1 KCNH3

2.88e-059428514GO:0098655
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR52B4 TAS2R1 TAS2R9 OR5AU1 OR4D10 OR6C70 OR6C6 TAS2R50 OR7G3 OR4F6

3.04e-054858510GO:0050907
GeneOntologyBiologicalProcesspositive regulation of long-chain fatty acid import across plasma membrane

ACSL1 ACSL6

5.02e-053852GO:0010747
GeneOntologyBiologicalProcessrenal system process involved in regulation of blood volume

GAS6 EMP2 F2R

5.27e-0518853GO:0001977
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR52B4 TAS2R1 TAS2R9 OR5AU1 OR4D10 OR6C70 OR6C6 TAS2R50 OR7G3 OR4F6

5.83e-055248510GO:0009593
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 GAS6 TCIRG1 KCNK6 PANX2 SLC30A1 F2R SLC30A4 ADCYAP1R1 KCNH3

6.94e-0511578515GO:0006812
GeneOntologyBiologicalProcesszinc export across plasma membrane

SLC30A1 SLC30A4

1.00e-044852GO:0140882
GeneOntologyBiologicalProcesspositive regulation of long-chain fatty acid import into cell

ACSL1 ACSL6

1.00e-044852GO:0140214
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

PTGDR PTGER2 ADCY6

1.13e-0423853GO:0071379
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 ATP6V0A4 GAS6 TCIRG1 KCNK6 OCA2 PANX2 SLC30A1 F2R SLC30A4 ADCYAP1R1 KCNH3

1.36e-0413748516GO:0006811
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR52B4 TAS2R1 TAS2R9 OR5AU1 OR4D10 OR6C70 OR6C6 TAS2R50 OR7G3 OR4F6

1.39e-045828510GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR52B4 TAS2R1 TAS2R9 PDE6B OR5AU1 OR4D10 OR6C70 OR6C6 TAS2R50 OR7G3 OR4F6

1.81e-047228511GO:0051606
GeneOntologyBiologicalProcessregulation of renal system process

GAS6 EMP2 F2R

2.05e-0428853GO:0098801
GeneOntologyBiologicalProcessintracellular chemical homeostasis

CACNA1D ATP2C1 ORMDL2 TRPC5 ATP6V0A4 GAS6 TCIRG1 OCA2 CYB561A3 SLC30A1 F2R ATP6AP1L

2.18e-048668512GO:0055082
GeneOntologyBiologicalProcessdentinogenesis

FAM20C TCIRG1

2.49e-046852GO:0097187
GeneOntologyBiologicalProcessrenal system process involved in regulation of systemic arterial blood pressure

GAS6 EMP2 F2R

2.79e-0431853GO:0003071
GeneOntologyBiologicalProcessglomerular filtration

GAS6 EMP2 F2R

3.37e-0433853GO:0003094
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import across plasma membrane

ACSL1 ACSL6

3.48e-047852GO:0010746
GeneOntologyBiologicalProcessrenal system process

ATP6V0A4 GAS6 EMP2 F2R ADCY6

3.79e-04149855GO:0003014
GeneOntologyBiologicalProcessresponse to prostaglandin

PTGDR PTGER2 ADCY6

4.37e-0436853GO:0034694
GeneOntologyBiologicalProcessrenal filtration

GAS6 EMP2 F2R

4.37e-0436853GO:0097205
GeneOntologyBiologicalProcesschemical homeostasis

CACNA1D ATP2C1 ORMDL2 TRPC5 ATP6V0A4 GAS6 TCIRG1 OCA2 CYB561A3 SLC30A1 F2R LYST ATP6AP1L ADCY6

5.53e-0412498514GO:0048878
GeneOntologyBiologicalProcessregulation of long-chain fatty acid import into cell

ACSL1 ACSL6

5.93e-049852GO:0140212
GeneOntologyBiologicalProcesspositive regulation of adenylate cyclase activity

CACNA1D ADORA3 ORAI1

5.98e-0440853GO:0045762
GeneOntologyBiologicalProcesscellular homeostasis

CACNA1D ATP2C1 ORMDL2 TRPC5 ATP6V0A4 GAS6 TCIRG1 OCA2 CYB561A3 SLC30A1 F2R ATP6AP1L

6.69e-049818512GO:0019725
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of bitter taste

TAS2R1 TAS2R9 TAS2R50

7.92e-0444853GO:0001580
GeneOntologyBiologicalProcessmetal ion transport

CACNA1D ORAI1 ATP2C1 SCN2A TRPC5 GAS6 KCNK6 SLC30A1 F2R SLC30A4 ADCYAP1R1 KCNH3

7.92e-0410008512GO:0030001
GeneOntologyBiologicalProcessregulation of cellular pH

ATP6V0A4 TCIRG1 OCA2 ATP6AP1L

8.09e-04101854GO:0030641
GeneOntologyBiologicalProcesszinc ion import into organelle

SLC30A1 SLC30A4

9.01e-0411852GO:0062111
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

ATP2C1 TRPC5 ATP6V0A4 TCIRG1 OCA2 CYB561A3 SLC30A1 F2R ATP6AP1L

9.20e-04611859GO:0030003
GeneOntologyBiologicalProcesspositive regulation of cyclase activity

CACNA1D ADORA3 ORAI1

1.02e-0348853GO:0031281
GeneOntologyBiologicalProcesssensory perception of bitter taste

TAS2R1 TAS2R9 TAS2R50

1.02e-0348853GO:0050913
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

ATP2C1 TRPC5 ATP6V0A4 TCIRG1 OCA2 CYB561A3 SLC30A1 F2R ATP6AP1L

1.04e-03622859GO:0006873
GeneOntologyBiologicalProcesslong-chain fatty acid import across plasma membrane

ACSL1 ACSL6

1.08e-0312852GO:0015911
GeneOntologyBiologicalProcesspositive regulation of lyase activity

CACNA1D ADORA3 ORAI1

1.09e-0349853GO:0051349
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1D ORAI1 SCN2A TRPC5 ATP6V0A4 TCIRG1 CATSPERB KCNK6 ATP6AP1L KCNH3

4.63e-055238410GO:1902495
GeneOntologyCellularComponenttransporter complex

CACNA1D ORAI1 SCN2A TRPC5 ATP6V0A4 TCIRG1 CATSPERB KCNK6 ATP6AP1L KCNH3

7.05e-055508410GO:1990351
GeneOntologyCellularComponentproton-transporting V-type ATPase complex

ATP6V0A4 TCIRG1 ATP6AP1L

2.12e-0429843GO:0033176
GeneOntologyCellularComponentcalcium channel complex

CACNA1D ORAI1 TRPC5 CATSPERB

2.14e-0473844GO:0034704
GeneOntologyCellularComponentcation channel complex

CACNA1D ORAI1 SCN2A TRPC5 CATSPERB KCNK6

3.71e-04235846GO:0034703
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase, V0 domain

ATP6V0A4 TCIRG1

7.03e-0410842GO:0000220
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1D ORAI1 SCN2A TRPC5 CATSPERB KCNK6 KCNH3

8.20e-04378847GO:0034702
GeneOntologyCellularComponentGolgi trans cisterna

YIPF2 GOLGA5

8.57e-0411842GO:0000138
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6V0A4 TCIRG1 ATP6AP1L

1.01e-0349843GO:0090533
GeneOntologyCellularComponentproton-transporting V-type ATPase, V0 domain

ATP6V0A4 TCIRG1

1.03e-0312842GO:0033179
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex

ATP6V0A4 TCIRG1 ATP6AP1L

1.27e-0353843GO:0016469
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP6V0A4 TCIRG1 ATP6AP1L

1.41e-0355843GO:0098533
GeneOntologyCellularComponentATPase complex

PBRM1 ATP6V0A4 TCIRG1 ATP6AP1L

1.82e-03129844GO:1904949
GeneOntologyCellularComponentendoplasmic reticulum membrane

RNF121 ACSL1 PIGN ACSL6 PGAP3 CYP2D6 POMGNT2 MGST3 ORMDL2 CYP8B1 TMCC2 OCA2 PANX2

1.88e-0312938413GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

RNF121 ACSL1 PIGN ACSL6 PGAP3 CYP2D6 POMGNT2 MGST3 ORMDL2 CYP8B1 TMCC2 OCA2 PANX2

1.96e-0312998413GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RNF121 ACSL1 PIGN ACSL6 PGAP3 CYP2D6 POMGNT2 MGST3 ORMDL2 CYP8B1 TMCC2 OCA2 PANX2

2.36e-0313278413GO:0042175
GeneOntologyCellularComponentGolgi membrane

RNF121 FAM20C ATP2C1 PGAP3 ABCA6 PANX2 EMP2 GOLGA5 ZDHHC8

2.41e-03721849GO:0000139
GeneOntologyCellularComponentlate endosome

YIPF2 TCIRG1 ATP9A CYB561A3 F2R SLC30A4

2.79e-03348846GO:0005770
GeneOntologyCellularComponentplasma membrane raft

ORAI1 EMP2 F2R ADCYAP1R1

2.93e-03147844GO:0044853
GeneOntologyCellularComponentGolgi medial cisterna

YIPF2 GOLGA5

3.82e-0323842GO:0005797
GeneOntologyCellularComponentT-tubule

CACNA1D SCN2A SLC30A1

3.97e-0379843GO:0030315
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase complex

ATP6V0A4 TCIRG1

4.87e-0326842GO:0016471
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex, proton-transporting domain

ATP6V0A4 TCIRG1

4.87e-0326842GO:0033177
DomainPMP22_EMP_MP20

PMP22 EMP1 EMP2 EMP3

4.95e-089854IPR004032
DomainPMP22_2

PMP22 EMP1 EMP2 EMP3

4.95e-089854PS01222
DomainPMP22_1

PMP22 EMP1 EMP2 EMP3

4.95e-089854PS01221
DomainG_PROTEIN_RECEP_F1_2

OR52B4 ADORA3 VN1R5 TAS2R9 OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR PTGER2 F2R OR7G3 OR4F6

2.64e-066918514PS50262
DomainGPCR_Rhodpsn

OR52B4 ADORA3 VN1R5 TAS2R9 OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR PTGER2 F2R OR7G3 OR4F6

2.68e-066928514IPR000276
DomainGPCR_Rhodpsn_7TM

OR52B4 ADORA3 TAS2R9 OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR PTGER2 F2R OR7G3 OR4F6

9.94e-066708513IPR017452
DomainG_PROTEIN_RECEP_F1_1

OR52B4 ADORA3 VN1R5 OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR PTGER2 F2R OR7G3 OR4F6

1.26e-056858513PS00237
DomainPMP22_Claudin

PMP22 EMP1 EMP2 EMP3

3.22e-0540854PF00822
DomainPMP22/EMP/MP20/Claudin

PMP22 EMP1 EMP2 EMP3

5.16e-0545854IPR004031
Domain7tm_1

OR52B4 ADORA3 OR5AU1 OR4D10 OR6C70 P2RY10 OR6C6 PTGDR PTGER2 F2R OR7G3 OR4F6

5.45e-056778512PF00001
DomainTM_Fragile-X-F-assoc

TMEM185B TMEM185A

1.22e-044852IPR019396
DomainTmemb_185A

TMEM185B TMEM185A

1.22e-044852PF10269
DomainV-type_ATPase_116kDa_su_euka

ATP6V0A4 TCIRG1

1.22e-044852IPR026028
DomainV_ATPase_I

ATP6V0A4 TCIRG1

1.22e-044852PF01496
DomainV-ATPase_116kDa_su

ATP6V0A4 TCIRG1

1.22e-044852IPR002490
DomainCu_amine_oxidase

YIPF2 AOC2

1.22e-044852IPR000269
DomainThbox_rcpt

PTGDR PTGER2

2.03e-045852IPR001105
DomainTAS2R

TAS2R1 TAS2R9 TAS2R50

2.19e-0426853PF05296
DomainT2R

TAS2R1 TAS2R9 TAS2R50

2.19e-0426853IPR007960
DomainProstanoid_rcpt

PTGDR PTGER2

5.63e-048852IPR008365
DomainCation_efflux

SLC30A1 SLC30A4

9.00e-0410852IPR002524
DomainCation_efflux

SLC30A1 SLC30A4

9.00e-0410852PF01545
Domain-

SLC30A1 SLC30A4

1.10e-03118521.20.1510.10
DomainCation_efflux_TMD

SLC30A1 SLC30A4

1.10e-0311852IPR027469
DomainDefensin_beta

DEFB130A DEFB130B

1.31e-0312852PF00711
DomainDefensin_beta-typ

DEFB130A DEFB130B

1.31e-0312852IPR001855
DomainIon_trans_dom

CACNA1D SCN2A TRPC5 KCNH3

1.82e-03114854IPR005821
DomainIon_trans

CACNA1D SCN2A TRPC5 KCNH3

1.82e-03114854PF00520
DomainOlfact_rcpt

OR52B4 OR5AU1 OR4D10 OR6C70 OR6C6 OR7G3 OR4F6

2.09e-03393857IPR000725
DomainAMP-binding_CS

ACSL1 ACSL6

6.20e-0326852IPR020845
DomainAMP_BINDING

ACSL1 ACSL6

7.17e-0328852PS00455
DomainAMP-binding

ACSL1 ACSL6

8.20e-0330852PF00501
DomainAMP-dep_Synth/Lig

ACSL1 ACSL6

8.20e-0330852IPR000873
DomainP_typ_ATPase

ATP2C1 ATP9A

1.17e-0236852IPR001757
DomainATPase_P-typ_P_site

ATP2C1 ATP9A

1.17e-0236852IPR018303
DomainATPASE_E1_E2

ATP2C1 ATP9A

1.17e-0236852PS00154
DomainATPase_P-typ_transduc_dom_A

ATP2C1 ATP9A

1.23e-0237852IPR008250
DomainE1-E2_ATPase

ATP2C1 ATP9A

1.23e-0237852PF00122
PathwayREACTOME_GPCR_LIGAND_BINDING

ADORA3 TAS2R1 TAS2R9 P2RY10 MLN PTGDR TAS2R50 PTGER2 F2R ADCYAP1R1

6.13e-054636710M507
PathwayKEGG_TASTE_TRANSDUCTION

TAS2R1 TAS2R9 TAS2R50 ADCY6

1.06e-0452674M5785
PathwayREACTOME_SENSORY_PERCEPTION

CACNA1D TAS2R1 PDE6B OR5AU1 OR4D10 OR6C70 SCN2A OR6C6 TAS2R50 OR7G3 OR4F6

1.85e-046366711M41834
PathwayWP_GPCRS_NONODORANT

ADORA3 TAS2R1 P2RY10 PTGDR PTGER2 F2R ADCYAP1R1

2.61e-04266677MM15843
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

ADORA3 PRSS2 P2RY10 PTGDR PTGER2 F2R ADCYAP1R1

2.98e-04272677M13380
PathwayREACTOME_DEFENSINS

PRSS2 DEFB130A DEFB130B

4.19e-0431673MM14568
PathwayREACTOME_SIGNALING_BY_GPCR

ADORA3 TAS2R1 TAS2R9 P2RY10 MLN PTGDR TAS2R50 PTGER2 F2R ADCY6 ADCYAP1R1

4.33e-047026711M746
Pubmed

Review of the GAS3 Family of Proteins and their Relevance to Cancer.

PMP22 EMP1 EMP2 EMP3

3.32e-11485427279240
Pubmed

Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1.

PMP22 EMP1 EMP2 EMP3

3.32e-1148548884260
Pubmed

Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus.

PMP22 EMP1 EMP2 EMP3

1.66e-10585412107182
Pubmed

Expression of epithelial membrane protein (EMP) 1, EMP 2, and EMP 3 in thyroid cancer.

EMP1 EMP2 EMP3

1.41e-08385334617578
Pubmed

Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3.

EMP1 EMP2 EMP3

1.41e-08385310331954
Pubmed

Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins.

EMP1 EMP2 EMP3

5.63e-0848538996089
Pubmed

Chromosomal mapping of Tmp (Emp1), Xmp (Emp2), and Ymp (Emp3), genes encoding membrane proteins related to Pmp22.

EMP1 EMP2 EMP3

1.67e-06108539615230
Pubmed

Human DP and EP2 prostanoid receptors take on distinct forms depending on the diverse binding of different ligands.

PTGDR PTGER2

5.90e-06285227636113
Pubmed

Epithelial Membrane Protein 2 Suppresses Non-Small Cell Lung Cancer Cell Growth by Inhibition of MAPK Pathway.

EMP1 EMP2

5.90e-06285233799364
Pubmed

Store-independent coupling between the Secretory Pathway Ca2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease.

ORAI1 ATP2C1

5.90e-06285229555205
Pubmed

Human EP2 prostanoid receptors exhibit more constraints to mutations than human DP prostanoid receptors.

PTGDR PTGER2

5.90e-06285225681680
Pubmed

A novel gene, FAM11A, associated with the FRAXF CpG island is transcriptionally silent in FRAXF full mutation.

TMEM185B TMEM185A

5.90e-06285212404111
Pubmed

Identification and molecular characterization of acyl-CoA synthetase in human erythrocytes and erythroid precursors.

ACSL1 ACSL6

5.90e-06285210548543
Pubmed

Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E receptor EP2 through cAMP elevation and protein kinase A.

PTGER2 F2R

5.90e-06285218537828
Pubmed

HNMP-1: a novel hematopoietic and neural membrane protein differentially regulated in neural development and injury.

PMP22 EMP3

5.90e-0628529204931
Pubmed

Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains.

ACSL1 ACSL6

5.90e-06285216834775
Pubmed

Embryonic expression of epithelial membrane protein 1 in early neurons.

PMP22 EMP1

5.90e-06285210521561
Pubmed

The Roles of ZnT1 and ZnT4 in Glucose-Stimulated Zinc Secretion in Prostate Epithelial Cells.

SLC30A1 SLC30A4

5.90e-06285233140261
Pubmed

Epithelial membrane protein-2 and epithelial membrane protein-3: two novel members of the peripheral myelin protein 22 gene family.

EMP2 EMP3

5.90e-0628528917086
Pubmed

Involvement of β-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum.

DEFB130A DEFB130B

5.90e-06285228181499
Pubmed

Epithelial membrane protein-1, peripheral myelin protein 22, and lens membrane protein 20 define a novel gene family.

PMP22 EMP1

5.90e-0628527499407
Pubmed

Effects of retinal degeneration and brain size upon spatial reversal learning in mice.

PDE6B PTGER2

1.77e-0538524704351
Pubmed

Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and bone.

ATP6V0A4 TCIRG1

1.77e-05385215800125
Pubmed

Alterations of zinc transporter proteins ZnT-1, ZnT-4 and ZnT-6 in preclinical Alzheimer's disease brain.

SLC30A1 SLC30A4

1.77e-05385219371353
Pubmed

The function of vacuolar ATPase (V-ATPase) a subunit isoforms in invasiveness of MCF10a and MCF10CA1a human breast cancer cells.

ATP6V0A4 TCIRG1

1.77e-05385224072707
Pubmed

Store-independent activation of Orai1 by SPCA2 in mammary tumors.

ORAI1 ATP2C1

1.77e-05385220887894
Pubmed

A novel family of mammalian taste receptors.

TAS2R1 TAS2R9 TAS2R50

1.82e-052185310761934
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR52B4 OR5AU1 OR4D10 OR6C70 OR6C6 OR7G3 OR4F6

2.06e-0534085711875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR52B4 OR5AU1 OR4D10 OR6C70 OR6C6 OR7G3 OR4F6

2.06e-0534085711802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR52B4 OR5AU1 OR4D10 OR6C70 OR6C6 OR7G3 OR4F6

2.18e-0534385732295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR52B4 OR5AU1 OR4D10 OR6C70 OR6C6 OR7G3 OR4F6

2.30e-0534685714611657
Pubmed

Receptors for bitter and sweet taste.

TAS2R1 TAS2R9 TAS2R50

3.12e-052585312139982
Pubmed

Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome.

VN1R5 DEFB130A DEFB130B

3.12e-052585320003482
Pubmed

Molecular mechanisms of bitter and sweet taste transduction.

TAS2R1 TAS2R9 TAS2R50

3.52e-052685311696554
Pubmed

SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation.

ORAI1 ATP2C1

3.53e-05485223840669
Pubmed

Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina.

PDE6B ADCY6

3.53e-05485237127773
Pubmed

Dynamic zinc pools in mouse choroid plexus.

SLC30A1 SLC30A4

3.53e-05485215257151
Pubmed

STIMulating stress fibers in endothelial cells.

ORAI1 F2R

3.53e-05485223512987
Pubmed

Differential localization of vacuolar H+-ATPases containing a1, a2, a3, or a4 (ATP6V0A1-4) subunit isoforms along the nephron.

ATP6V0A4 TCIRG1

3.53e-05485217595521
Pubmed

The GAS6-AXL signaling network is a mesenchymal (Mes) molecular subtype-specific therapeutic target for ovarian cancer.

GAS6 LYST

3.53e-05485227703030
Pubmed

Functional reconstitution of G-protein-coupled receptor-mediated adenylyl cyclase activation by a baculoviral co-display system.

PTGER2 ADCY6

3.53e-05485218403039
Pubmed

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.

TAS2R1 TAS2R9 TAS2R50

3.95e-052785312581520
Pubmed

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.

TAS2R1 TAS2R9 TAS2R50

4.42e-052885315744053
Pubmed

Transmembrane 163 (TMEM163) protein interacts with specific mammalian SLC30 zinc efflux transporter family members.

SLC30A1 SLC30A4

5.87e-05585236204728
Pubmed

Store-operated Ca2+ entry and Ca2+ responses to hypothalamic releasing hormones in anterior pituitary cells from Orai1-/- and heptaTRPC knockout mice.

ORAI1 TRPC5

5.87e-05585230452936
Pubmed

The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos.

ATP6V0A4 TCIRG1

5.87e-05585235948619
Pubmed

a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit a.

ATP6V0A4 TCIRG1

5.87e-05585211498539
Pubmed

Slate--a new coat color mutant in the mouse.

OCA2 LYST

5.87e-05585213943454
Pubmed

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family.

ACSL1 ACSL6

5.87e-05585215292367
Pubmed

Genes specifically expressed at growth arrest of mammalian cells.

PMP22 GAS6

5.87e-0558523409319
Pubmed

Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.

ACSL1 ACSL6

5.87e-05585224269233
Pubmed

Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor.

TMEM185B TMEM185A

5.87e-05585215525354
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

DYM MGST3 PANX2 ATP9A SLC30A1 ZDHHC8 ADCYAP1R1

6.24e-0540585738187761
Pubmed

Evolution of bitter taste receptors in humans and apes.

TAS2R1 TAS2R9 TAS2R50

7.98e-053485315496549
Pubmed

Dissociation of heterotrimeric g proteins in cells.

ADORA3 P2RY10 MLN F2R ADCYAP1R1

8.03e-0517985518577758
Pubmed

Prostanoid receptors in anagen human hair follicles.

PTGDR PTGER2

8.80e-05685218005048
Pubmed

Abundant expression of zinc transporters in the amyloid plaques of Alzheimer's disease brain.

SLC30A1 SLC30A4

8.80e-05685218639746
Pubmed

Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.

ATP6V0A4 TCIRG1

8.80e-05685221307348
Pubmed

Heterodimerization, altered subcellular localization, and function of multiple zinc transporters in viable cells using bimolecular fluorescence complementation.

SLC30A1 SLC30A4

8.80e-05685225657003
Pubmed

Optic nerve compression and retinal degeneration in Tcirg1 mutant mice lacking the vacuolar-type H-ATPase a3 subunit.

ATP6V0A4 TCIRG1

1.23e-04785220711468
Pubmed

Definition of Prostaglandin E2-EP2 Signals in the Colon Tumor Microenvironment That Amplify Inflammation and Tumor Growth.

PTGDR PTGER2

1.23e-04785226018088
Pubmed

Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.

ACSL1 ACSL6

1.23e-04785217197235
Pubmed

Thromboxane A2 and prostaglandin F2alpha mediate inflammatory tachycardia.

PTGDR PTGER2

1.64e-04885215834430
Pubmed

The prostaglandin receptor EP4 suppresses colitis, mucosal damage and CD4 cell activation in the gut.

PTGDR PTGER2

1.64e-04885211927615
Pubmed

Association between polymorphisms in prostanoid receptor genes and aspirin-intolerant asthma.

PTGDR PTGER2

1.64e-04885217496729
Pubmed

Prostanoid receptors: structures, properties, and functions.

PTGDR PTGER2

1.64e-04885210508233
Pubmed

Dual roles of PGE2-EP4 signaling in mouse experimental autoimmune encephalomyelitis.

PTGDR PTGER2

1.64e-04885220566843
Pubmed

Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta.

PTGDR PTGER2

1.64e-04885219966781
Pubmed

Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression.

PTGDR PTGER2

2.10e-04985221460251
Pubmed

Involvement of prostaglandin E receptor subtype EP(4) in colon carcinogenesis.

PTGDR PTGER2

2.10e-04985211782353
Pubmed

Genetic control of retinal ganglion cell projections.

OCA2 LYST

2.10e-049852102659
Pubmed

Zinc transporters protein level in postmortem brain of depressed subjects and suicide victims.

SLC30A1 SLC30A4

2.10e-04985227661418
Pubmed

Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9.

SLC30A1 SLC30A4

2.10e-04985217971500
Pubmed

Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis.

PTGDR PTGER2

2.10e-04985231688905
Pubmed

The fine structure of melanogenesis in coat color mutants of the mouse.

OCA2 LYST

2.10e-0498524634048
Pubmed

Zinc transporter 2 (SLC30A2) can suppress the vesicular zinc defect of adaptor protein 3-depleted fibroblasts by promoting zinc accumulation in lysosomes.

SLC30A1 SLC30A4

2.62e-041085217349999
Pubmed

A family of candidate taste receptors in human and mouse.

TAS2R1 TAS2R9

3.20e-041185210766242
Pubmed

A plethora of taste receptors.

TAS2R1 TAS2R9

3.20e-041185210774719
Pubmed

T2Rs function as bitter taste receptors.

TAS2R1 TAS2R9

3.20e-041185210761935
Pubmed

Overview of mammalian zinc transporters.

SLC30A1 SLC30A4

3.20e-041185214704853
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ORAI1 FAM20C PGAP3 POMGNT2 TMCC2 AOC2 DISP2 ZDHHC8 LYST KCNH3

3.64e-041105851035748872
Pubmed

Structure and Roles of V-type ATPases.

ATP6V0A4 TCIRG1

4.52e-041385232001091
Pubmed

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.

FAM20C EMP1 EMP2 ATP9A

5.95e-0415685422008794
Pubmed

Selective inhibition of heterotrimeric Gs signaling. Targeting the receptor-G protein interface using a peptide minigene encoding the Galpha(s) carboxyl terminus.

PTGDR PTGER2 ADCYAP1R1

6.85e-047085312036966
Pubmed

E2F6 associates with BRG1 in transcriptional regulation.

PBRM1 PTGDR

7.84e-041785223082233
Pubmed

Structures of a Complete Human V-ATPase Reveal Mechanisms of Its Assembly.

ATP6V0A4 TCIRG1

7.84e-041785233065002
Pubmed

Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver.

CYP2D6 CYP8B1

7.84e-041785227197076
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR5AU1 OR6C70 OR7G3

8.06e-047485315081110
Pubmed

Introduction: V-ATPases 1992-1998.

ATP6V0A4 TCIRG1

8.80e-041885210340843
Pubmed

Animal plasma membrane energization by proton-motive V-ATPases.

ATP6V0A4 TCIRG1

8.80e-041885210440860
Pubmed

The vacuolar H+-ATPase: a universal proton pump of eukaryotes.

ATP6V0A4 TCIRG1

8.80e-04188529210392
Pubmed

Vacuolar and plasma membrane proton-adenosinetriphosphatases.

ATP6V0A4 TCIRG1

8.80e-041885210221984
Pubmed

Structure and properties of the vacuolar (H+)-ATPases.

ATP6V0A4 TCIRG1

8.80e-041885210224039
Pubmed

Structure, function and regulation of the vacuolar (H+)-ATPase.

ATP6V0A4 TCIRG1

9.83e-04198529442887
Pubmed

Localization of growth arrest-specific genes on mouse chromosomes 1, 7, 8, 11, 13, and 16.

PMP22 GAS6

1.20e-03218521347472
Pubmed

Cyclic-Nucleotide- and HCN-Channel-Mediated Phototransduction in Intrinsically Photosensitive Retinal Ganglion Cells.

PDE6B TRPC5

1.20e-032185230270038
Pubmed

HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure.

CACNA1D GAS6

1.32e-032285231286141
Pubmed

The vacuolar (H+)-ATPases--nature's most versatile proton pumps.

ATP6V0A4 TCIRG1

1.32e-032285211836511
Pubmed

Proton translocation driven by ATP hydrolysis in V-ATPases.

ATP6V0A4 TCIRG1

1.32e-032285212788495
Pubmed

Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.

ATP6V0A4 TCIRG1

1.32e-032285214580332
InteractionCCR6 interactions

PIGN DYM ATP2C1 GOLGA5 ATP9A

2.03e-0589755int:CCR6
InteractionKLRC1 interactions

PMP22 ACSL1 GAS6 EMP1 EMP3 CYB561A3

3.24e-05163756int:KLRC1
Cytoband12q13.2

ORMDL2 OR6C70 OR6C6

1.50e-045585312q13.2
Cytoband12p11.22

TMTC1 MANSC4

2.21e-041285212p11.22
CytobandEnsembl 112 genes in cytogenetic band chr14q22

GPR137C PTGDR PTGER2

7.27e-0494853chr14q22
CytobandEnsembl 112 genes in cytogenetic band chr12q13

ORMDL2 OR6C70 OR6C6 ADCY6 KCNH3

1.16e-03423855chr12q13
Cytoband14q32.12

CATSPERB GOLGA5

1.33e-032985214q32.12
Cytoband14q22.1

GPR137C PTGDR

1.42e-033085214q22.1
Cytoband3p22.1

POMGNT2 CYP8B1

2.52e-03408523p22.1
Cytoband7q34

PRSS2 CLEC2L ATP6V0A4

3.75e-031678537q34
GeneFamilyTaste 2 receptors

TAS2R1 TAS2R9 TAS2R50

2.92e-04396031162
GeneFamilyProstaglandin (prostanoid) receptors

PTGDR PTGER2

3.84e-049602207
GeneFamilyV-type ATPases

ATP6V0A4 TCIRG1

2.62e-0323602415
GeneFamilyAcyl-CoA synthetase family

ACSL1 ACSL6

3.34e-032660240
CoexpressionKONDO_PROSTATE_CANCER_WITH_H3K27ME3

OR52B4 TMTC1 TAS2R1 ABCA6 OR4D10 OR6C70 OR6C6

3.06e-06194847M7281
CoexpressionNIKOLSKY_BREAST_CANCER_14Q22_AMPLICON

GPR137C PTGDR PTGER2

1.13e-0514843M17961
CoexpressionENK_UV_RESPONSE_EPIDERMIS_DN

PMP22 ACSL1 PIGN MGST3 GAS6 OCA2 EMP1 EMP2 F2R

3.88e-05512849M4508
CoexpressionGSE4142_PLASMA_CELL_VS_MEMORY_BCELL_DN

ACSL6 ORAI1 ORMDL2 TMCC2 GAS6 KCNK6

4.54e-05200846M6396
CoexpressionGSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP

MAU2 PTGER2 SLC30A4 LYST ADCY6 KCNH3

4.54e-05200846M4576
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000

PMP22 CYP2D6 TMEM45A SCN2A GAS6 EMP1 EMP2 EMP3 CYB561A3

4.25e-06369729gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlasdev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#1_top-relative-expression-ranked_200

PMP22 SCN2A DISP2 ADCYAP1R1

3.14e-0553724gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k1_200
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

PMP22 TMTC1 CYP2D6 TMEM45A SCN2A ATP6V0A4 GAS6 EMP1 EMP2 EMP3 CYB561A3

5.86e-057787211gudmap_kidney_adult_RenalCapsule_1000
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 MGST3 DEFB130A TMCC2 ATP6V0A4 EMP2 SLC30A1

5.30e-08181847cd81bc307e2bc42c1e9b24d5645ab65fa18c6133
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 ORAI1 TMCC2 ATP6V0A4 EMP1 EMP2

8.20e-071698468a6d05b5d60b2b2e43a8ff7521feb79cd6dbd940
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL1 FAM20C PTPRD ABCA6 CYP8B1 ATP9A

1.30e-06183846d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCelldroplet-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PMP22 MGST3 TMCC2 ATP6V0A4 EMP2 SLC30A1

1.77e-0619384625129080f8a40b2988a5d9dfec36ff9e72c27e61
ToppCellMacrophages-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

PMP22 MGST3 AOC2 EMP1 EMP3 SLC30A1

1.83e-06194846cbb1c65ccee58b2892f7d3fa45773099411c6104
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 MGST3 TMCC2 EMP1 EMP2 SLC30A1

1.83e-061948468deeb3e00237e3d9ad5a1457cd0061576421b9e9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 MGST3 TMCC2 EMP1 EMP2 SLC30A1

1.83e-06194846b81801fb16e8bd0d6083fe32866051d3c60f3dc7
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PMP22 TMTC1 OCA2 EMP3 PTGER2 F2R

1.94e-06196846a7adc0e0baef261d0937e4e8351321d41beca82f
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

PMP22 CACNA1D KCNK6 RSPO4 EMP2 F2R

2.06e-06198846e0e47cf65774191981840b22905b2094b95abe0f
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PMP22 TMTC1 GAS6 EMP1 EMP2 F2R

2.12e-06199846e6715288a586631676722f2323f0d833431161cf
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ATP2C1 PTPRD ABCA6 MAU2 ADCYAP1R1

1.57e-0516684565dafed953b01a9830b54309af75c7a561e88336
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 MGST3 TMCC2 EMP1 EMP2

1.86e-05172845490745024730df6357f6c2b81d7a64e21557c0d5
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

PMP22 ADORA3 FAM20C ABCA6 EMP1

1.97e-051748454c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

ADORA3 FAM20C ABCA6 EMP1 MEI1

2.14e-05177845470f54fe2b21c7350ea471e02039461a3808f700
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 ABCA6 CATSPERB KCNK6 RSPO4

2.20e-0517884509475e522dc1b8cf9ff1c25de5d1e3082b162948
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 ABCA6 CATSPERB KCNK6 RSPO4

2.20e-0517884535de8f791b0e78a6caf52ff095f05e204a59e828
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 ABCA6 CATSPERB KCNK6 RSPO4

2.20e-05178845000d25f3f13cc76cf39c46c312c6fafc2ea4f368
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

PMP22 GAS6 KCNK6 EMP1 CYB561A3

2.32e-05180845be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCellMatrixFB-Fibroblast-A|MatrixFB / shred on cell class and cell subclass (v4)

PMP22 CACNA1D PTPRD EMP2 PTGER2

2.32e-05180845adc64ad6033af705dd7b9163a83e20ef5c59f6eb
ToppCelldroplet-Kidney-nan-21m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSL1 FAM20C MGST3 ATP6V0A4 GAS6

2.44e-05182845942c18a27b22fb33a5200d5717cad972f3ef0576
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-T_lymphocytic-type_I_NK_T_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PTGDR PTGER2 CBLB F2R LYST

2.44e-051828459d727ab84da8de33f1021b492c90d8b4c2a8ea23
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CLEC2L SCN2A KCNK6 F2R ADCY6

2.57e-05184845ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCellBAL-Control-Myeloid-MoAM-MoAM4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PMP22 FAM20C GAS6 EMP1 MEI1

2.64e-0518584529d7ddcb9a2e45f76cd5611f7c52b6df689effd3
ToppCellBAL-Control-Myeloid-MoAM-MoAM4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PMP22 FAM20C GAS6 EMP1 MEI1

2.64e-05185845780bdb63ef913a09930063286011c9108381d3a9
ToppCellBAL-Control-Myeloid-MoAM-MoAM4|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PMP22 FAM20C GAS6 EMP1 MEI1

2.64e-05185845274b8acccdfe434d14af4cb32fb615c06ec98435
ToppCellBAL-Control-Myeloid-MoAM-MoAM4-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PMP22 FAM20C GAS6 EMP1 MEI1

2.64e-05185845b640d9ed6a1e6aa595053065bb992efc0402353e
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PMP22 ADORA3 GAS6 EMP1 EMP2

2.71e-051868459673367cb53bafb873a01ef6bda11d9f392ce648
ToppCellP07-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PMP22 MGST3 TMCC2 EMP1 EMP2

2.93e-05189845fcfb28bd96471affc13e55aa7228f594aaa967cd
ToppCellP07-Endothelial-unknown_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PMP22 MGST3 TMCC2 EMP1 EMP2

2.93e-05189845f515a04ae1746257d4568cea13a3dd75b4b05275
ToppCell(1)_T_CD8_gd|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

PTGDR PTGER2 CBLB F2R LYST

2.93e-0518984562eda4bcfd21d5025ac676d524994ede22721c1d
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 ABCA6 TMEM45A EMP1 ADCYAP1R1

3.00e-051908458cb950effc449ae59a915132ecc079be54d1acfe
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 ABCA6 TMEM45A EMP1 ADCYAP1R1

3.00e-051908455dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 ABCA6 TMEM45A EMP1 ADCYAP1R1

3.00e-0519084517a73a658fb30a4322b31e38db7b240023738f29
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

EMP3 PTGDR PTGER2 CBLB F2R

3.00e-0519084566d29f53f129fc18771f6214316a913eeaccd55e
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PMP22 CACNA1D PTPRD ABCA6 TMEM45A

3.00e-05190845841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PMP22 CACNA1D PTPRD ABCA6 TMEM45A

3.00e-05190845d60395739458d7f47a3350ade751fe3819500320
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D PRSS2 FAM20C WDR6 DISP2

3.08e-05191845d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|lymph-node_spleen / Manually curated celltypes from each tissue

PTGDR PTGER2 CBLB F2R LYST

3.08e-05191845f802a4686ecf00e8302047bfe23356f24b266cf8
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PMP22 MGST3 TMCC2 EMP2 SLC30A1

3.08e-0519184540e617d3c93f03ae87baf6c0b2304b617f5fe782
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4/8-lo|lymph-node_spleen / Manually curated celltypes from each tissue

PTGDR PTGER2 CBLB F2R LYST

3.16e-051928454d72b9264ed62e0c08cde4078061b348253f6989
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 MGST3 TMCC2 EMP1 EMP2

3.16e-0519284553d438e35c14e7656585942b788459e6d843c555
ToppCelldroplet-Lung-1m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PMP22 MGST3 TMCC2 EMP1 EMP2

3.16e-05192845ff435141329e3e29fa9b08a4d5b2f55074e7f9ab
ToppCell(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells|(1)_Control_(PBS) / Stress and Cell class

PMP22 GAS6 EMP1 EMP2 EMP3

3.16e-0519284540f380f5f0bed63a7404be050838ebd01ef08987
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 MGST3 TMCC2 EMP1 EMP2

3.16e-051928459a1aeac3ecf31f865a23d8ee15a82aef31779089
ToppCellControl-Myeloid-MoAM4|Control / Disease group,lineage and cell class (2021.01.30)

PMP22 FAM20C GAS6 EMP1 MEI1

3.16e-051928451da7c303a2e36af4a9d8ec30a11380d9b1897922
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 MGST3 TMCC2 EMP1 EMP2

3.16e-05192845f094ac378e635cf5820e8a8b7a0152073a51ceae
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D PTPRD ABCA6 RSPO4 OCA2

3.23e-051938459f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellLAM-Myeloid-DC|Myeloid / Condition, Lineage and Cell class

ACSL6 ADORA3 ABCA6 GAS6 KCNK6

3.23e-05193845f665cce40053ae5d6e28f9f70ddf78e8598c9514
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 MGST3 TMCC2 EMP1 EMP2

3.32e-05194845fc40ab57be3a15c043e3414c2c678c1dc52207c8
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1D PTPRD ABCA6 RSPO4 OCA2

3.32e-0519484571d3c7448b1734de54187f902f65649f9283bd4c
ToppCelldroplet-Lung-nan-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 MGST3 TMCC2 ATP6V0A4 EMP2

3.32e-05194845f35f03412b596b6b570b377ba1a607409d984bb1
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 MGST3 TMCC2 EMP1 EMP2

3.32e-0519484550fa7c7940b113427c87fbdb9057fef8e1ce52c5
ToppCellnormal_Lymph_Node-T/NK_cells-Naive_CD8+_T|normal_Lymph_Node / Location, Cell class and cell subclass

PTGDR PTGER2 CBLB F2R LYST

3.32e-0519484581b8f60d3b81e494051721ce9b8b6aefd415442c
ToppCellIPF-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

PMP22 ACSL1 FAM20C EMP1 EMP3

3.40e-0519584550edda117b438b9c3616191884007466f6d974f0
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PMP22 ADORA3 ABCA6 GAS6 EMP2

3.40e-051958454008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell(010)_cDC|World / immune cells in Peripheral Blood (logTPM normalization)

PMP22 FAM20C GAS6 KCNK6 ADCY6

3.40e-051958454aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMP22 CACNA1D PTPRD TMEM45A PTGER2

3.40e-051958458aa753934debffe5ae4b5eecb6b50c46d17cc3ec
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PMP22 TMTC1 MGST3 TMCC2 EMP2

3.40e-051958457e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 PTPRD GAS6 EMP1 EMP2

3.48e-051968456bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 PTPRD GAS6 EMP1 EMP2

3.48e-05196845c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 LRRC3B GAS6 F2R ADCYAP1R1

3.48e-051968459d18381d7aaa063094a5df769a04c73350471525
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMP22 PTPRD GAS6 EMP1 F2R

3.48e-0519684561bee32ca299219f31a30b57124e44e85b798e9f
ToppCell(2)_5-FU-(3)_LEPR+_perivascular_cells|(2)_5-FU / Stress and Cell class

PMP22 MGST3 GAS6 EMP1 EMP3

3.48e-05196845cc0a172de71d9a1a882c9e78652dae70e007d012
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 CACNA1D PTPRD ABCA6 RSPO4

3.48e-051968459737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACSL6 PRSS2 P2RY10 PTGER2 CBLB

3.48e-05196845ecbc2baec21e85e6d8eac32d46f2c966fc35e223
ToppCellMacrophages-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

PMP22 FAM20C EMP1 EMP3 PTGER2

3.48e-05196845861c402ed8b8fde3582cc777c1357b45f5a2489b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 CACNA1D PTPRD ABCA6 RSPO4

3.48e-05196845cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 LRRC3B GAS6 F2R ADCYAP1R1

3.48e-05196845a52cb512c6173be92aa9c4d96e2abbc32f45478d
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 LRRC3B GAS6 F2R ADCYAP1R1

3.48e-05196845afddacc0fb8b9c73dad5333137deb471a6ebdc06
ToppCell367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PMP22 ADORA3 ABCA6 GAS6 EMP2

3.48e-05196845e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

PMP22 ABCA6 RSPO4 EMP2 F2R

3.57e-05197845156155c2f0c1a2461e45803da578af18ee221660
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

PMP22 ABCA6 RSPO4 EMP2 F2R

3.57e-05197845d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellIPF-Myeloid-Macrophage|IPF / Disease state, Lineage and Cell class

PMP22 ACSL1 FAM20C EMP1 EMP3

3.57e-05197845a2ffb33c7cad6be43cbb8ed9a91338923cc07db4
ToppCellMonocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PMP22 ADORA3 MGST3 TCIRG1 EMP1

3.57e-051978458a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PMP22 CACNA1D PTPRD ABCA6 RSPO4

3.57e-0519784513896ec65ccda0b928c91d41112dc01b480036b7
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRD ATP6V0A4 GAS6 EMP1 F2R

3.57e-05197845cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell15-Distal-Mesenchymal-Mesenchyme_RSPO2+|Distal / Age, Tissue, Lineage and Cell class

PMP22 CACNA1D PTPRD ABCA6 EMP3

3.65e-05198845e87d1fe2befbd32b0c723ab43b9de95495ea3ee3
ToppCellSepsis-ICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, condition lineage and cell class

PMP22 GAS6 KCNK6 EMP1 CYB561A3

3.74e-0519984590ddd686b8f39c6f6134b9b048396cebcf8d0448
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PMP22 TMTC1 GAS6 EMP2 F2R

3.74e-051998458b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCellLPS_only-Hematopoietic_Myeloid|LPS_only / Treatment groups by lineage, cell group, cell type

ACSL1 TCIRG1 EMP3 PTGDR PTGER2

3.74e-0519984520523dee39a4c5f6423259920f108127b47525c4
ToppCellSigmoid-T_cell-Th1|T_cell / Region, Cell class and subclass

PIGN ACSL6 EMP1 PTGER2 F2R

3.83e-05200845bc9433a8ec3a6f10816730a32b821c63d78e6e87
ToppCellmLN-(1)_T_cell-(10)_CD8_T|mLN / shred on region, Cell_type, and subtype

PTGDR PTGER2 CBLB F2R LYST

3.83e-052008456f02ba3a76e8aa3083efea9cb4ee587799c61fda
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FAM20C MGST3 TCIRG1 EMP1 EMP3

3.83e-05200845d0ffd0d403a335c477c1b72391078b1595d9630c
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PMP22 CACNA1D PTPRD ABCA6 TMEM45A

3.83e-05200845b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell18-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

PMP22 PTPRD ABCA6 PTGER2 F2R

3.83e-0520084514ae55660f7412518dcb5cb982f6fe9f23553cfb
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PMP22 CACNA1D PTPRD ABCA6 TMEM45A

3.83e-0520084550ca6550998e461ef26dd670351060bd940765a8
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PMP22 TMTC1 PTPRD ABCA6 EMP1

3.83e-05200845a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PMP22 CACNA1D PTPRD ABCA6 RSPO4

3.83e-052008458c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

PMP22 CACNA1D PTPRD ABCA6 F2R

3.83e-05200845aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_alveolar|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PMP22 CACNA1D ABCA6 KCNK6 RSPO4

3.83e-05200845750ff51c9de08aecec230f4a402e0bf5a789f24c
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PMP22 CACNA1D PTPRD ABCA6 F2R

3.83e-05200845a510deaada669e690329183e18df02870bd204b3
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PMP22 CACNA1D PTPRD ABCA6 TMEM45A

3.83e-0520084544a68bacdb3d5bf563bd35952176995850933a81
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACSL1 TCIRG1 PTGDR PTGER2 LYST

3.83e-05200845fd1b6db3c62f5a205b769ba0e61433dae6285b67
ToppCellBiopsy_Control_(H.)-Immune-T_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

P2RY10 PTGDR PTGER2 CBLB F2R

3.83e-052008453545706d133b29df61affe8ac47b6c9fe85f7775
ToppCellLPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACSL1 TCIRG1 PTGDR PTGER2 LYST

3.83e-052008450b7573ec4e9c67c7d11dd8f5011a70bade30e930
ToppCellmLN-T_cell-CD8_T|mLN / Region, Cell class and subclass

PTGDR PTGER2 CBLB F2R LYST

3.83e-05200845a221213f9245297a5d6196564c1043f8c17eb857
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

PMP22 CACNA1D PTPRD ABCA6 TMEM45A

3.83e-05200845dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PMP22 CACNA1D PTPRD ABCA6 F2R

3.83e-05200845dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellerythropoietic-Erythrocyte|erythropoietic / Lineage and Cell class

ACSL6 TMCC2

5.14e-0568422e2f58fb39133c7195e8bedbdc56656803e92838
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

PMP22 ABCA6 EMP1 F2R

1.04e-0412984413cd10ffdd8f1ef7721884e9efd2cf25f170f414
DrugLetrozole [112809-51-5]; Up 200; 14uM; HL60; HT_HG-U133A

ACSL1 ADORA3 TAS2R1 PBRM1 PGAP3 TMCC2 EMP2 F2R

4.20e-071858482916_UP
Drugcaffeine

CACNA1D ADORA3 ORAI1 TAS2R1 DYM ATP2C1 CYP2D6 PDE6B CYP8B1 EMP2 ADCY6

6.85e-065628411CID000002519
Diseaseautosomal recessive osteopetrosis 1 (implicated_via_orthology)

ATP6V0A4 TCIRG1

7.59e-055822DOID:0110942 (implicated_via_orthology)
Diseaserenal tubular acidosis (implicated_via_orthology)

ATP6V0A4 TCIRG1

2.11e-048822DOID:14219 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

PMP22 SCN2A

5.83e-0413822C0751122
Diseasetriacylglycerol 54:2 measurement

MLN MAU2

6.79e-0414822EFO_0010420
Diseaseeotaxin measurement

POMGNT2 CYP8B1 OCA2

1.46e-0380823EFO_0008122
Diseaselymphocyte count, response to vaccine

PMP22 EMP1

1.70e-0322822EFO_0004587, EFO_0004645
DiseaseCCL11 measurement

POMGNT2 CYP8B1

1.86e-0323822EFO_0005188
DiseaseBradycardia

CACNA1D CYP2D6

2.37e-0326822C0428977
DiseaseAgouti-related protein measurement

ABCA6 CMTM4

2.56e-0327822EFO_0008016

Protein segments in the cluster

PeptideGeneStartEntry
DMVLTNHFLVILTSL

CATSPERB

246

Q9H7T0
LIFTHASIMSLLAIA

ADORA3

91

P0DMS8
MAVLVLLTAVLLAFH

ADCY6

156

O43306
LHISSIGKLAMIFVL

ADCY6

831

O43306
LISFLPLAHMFERVV

ACSL1

316

P33121
LINHFDLSILITTMV

ABCA6

1146

Q8N139
FMGTAVLVHLALTLV

DISP2

621

A7MBM2
LLLASAVISVLMHQF

ATP2C1

86

P98194
AALFVLMEALAHLHL

OCA2

686

Q04671
LDHLLLLALMTVLFT

PTGDR

261

Q13258
SAVVLTLLMAVFALL

KCNH3

356

Q9ULD8
LVAMVLVLQTFRHVS

KCNK6

246

Q9Y257
MHLKIVLAFLALSLI

AOC2

1

O75106
HLLELIAFLLAVMTL

OR6C70

191

A6NIJ9
YIILVGLLHMVLLSI

ORMDL2

26

Q53FV1
MLVLLAGIFVVHIAT

EMP1

1

P54849
LLIQELIHNLFVSVM

PBRM1

776

Q86U86
LVIFQRFIMILTEHL

NCBP1

711

Q09161
IARVFVIIYMALLHL

GOLGA5

696

Q8TBA6
LHLGFIMASLLFLVV

GPR137C

166

Q8N3F9
LSLIFSHMLAEIKAI

CBLB

146

Q13191
VAVHLFALMISTCIL

ORAI1

131

Q96D31
LFRLIALEMAKIHTI

ETNK2

171

Q9NVF9
LDVVLIFISYMLILH

OR52B4

211

Q8NGK2
AFSMLSAHVIVVVLV

OR4F6

236

Q8NGB9
DHLILLAIMTITFAV

PTGER2

261

P43116
VIHLMDIAIIATDLA

PDE6B

656

P35913
MHVAEVAVNVILLLS

MANSC4

1

A6NHS7
LLLQSFVLMILCFHS

LRRC3B

16

Q96PB8
LVVVSLVMVALQHFA

ATP9A

311

O75110
MHLSAVFNALLVSVL

POMGNT2

1

Q8NAT1
VLLTGAASFIMVAHL

MGST3

11

O14880
MAGVVHVSLAALLLL

ADCYAP1R1

1

P41586
LMEVFLSILHNLFVI

MEI1

571

Q5TIA1
MLHLATADVLFVSVL

F2R

141

P25116
MKLHSLISVLLLFVT

DEFB130B

1

P0DP73
MLVLLAFIIAFHITS

EMP2

1

P54851
SHHVYMALIILLILT

DYM

391

Q7RTS9
VLILMVFLVACALHI

FAM20C

11

Q8IXL6
VIVAIFLLLVDLMHR

CYP2D6

11

P10635
QLVVLAVEHTALALM

GAS6

551

Q14393
MLFRTVLHLLSVDVS

LYST

326

Q99698
LLHAALHLMAFVLTV

CYB561A3

81

Q8NBI2
LHLMAFVLTVVGLVA

CYB561A3

86

Q8NBI2
MSLLLLVVSALHILI

EMP3

1

P54852
MKLHSLISVLLLFVT

DEFB130A

1

P0DP74
ILSSFQVILLEHIIM

MAU2

331

Q9Y6X3
FLVAIILAVLHLHSM

RYK

241

P34925
HIFTNLILVFIMLSS

CACNA1D

886

Q01668
ALSEVKLFILLMVTH

CYP8B1

446

Q9UNU6
IFMINLSVADLAHVL

P2RY10

71

O00398
MNLIILVNLIHLFIF

PANX2

301

Q96RD6
MVHVARLLLLLLTFF

PTPRD

1

P23468
VSAFRALLLLMLTVH

PGAP3

196

Q96FM1
KLAHTDIFILELLMI

OR4D10

186

Q8NGI6
TLIFLVCHLLVANMD

TAS2R50

136

P59544
CLLLLVAHAVDMLAL

RSPO4

6

Q2I0M5
LALMAVLLVFVSTIA

TMCC2

651

O75069
IAVGIHLLLLMFEVL

TMEM185A

86

Q8NFB2
IAVGIHLLLLMFEVL

TMEM185B

86

Q9H7F4
LGNLVMFLLIHVSAT

OR5AU1

91

Q8NGC0
ALLHTLMVLQLTFCI

OR7G3

156

Q8NG95
LLHSSTMVVAGIFLL

MT-ND5

246

P03915
HVLELMSFTLAVVTL

OR6C6

191

A6NF89
VLVMASLLCVSHLLL

SLC23A3

56

Q6PIS1
LISFLPLAHMFERVI

ACSL6

316

Q9UKU0
VLLFAILVVMSILAS

CLEC2L

76

P0C7M8
VVTGVLLIMFSLNLH

CMTM4

96

Q8IZR5
MLESHLIIYFLLAVI

TAS2R1

1

Q9NYW7
ATIFLAVVMALLSLH

TMTC1

356

Q8IUR5
AVAALLVVHVAAMLA

MLN

6

P12872
AHMRAIKAVIIFLLL

TAS2R9

226

Q9NYW1
LAIKILVHSLFNMLI

SCN2A

121

Q99250
HAEMVLILIATLVVA

RNF121

51

Q9H920
MNLLLILTFVAAAVA

PRSS2

1

P07478
SLHVFVLAVEMLQLE

WDR6

1006

Q9NNW5
FLIVLVISDIMALHF

PIGN

861

O95427
AILLIMEGLSAFLHA

ATP6V0A4

791

Q9HBG4
FHRLEVLSAMISVLL

SLC30A4

176

O14863
DMIISHLSLIHILLL

VN1R5

81

Q7Z5H4
LFLLSLSAHMVGVVA

ZDHHC8

151

Q9ULC8
TFLFMLLLASQHIVR

TRPC5

376

Q9UL62
VLLSVVVLLHALLAM

YIPF2

261

Q9BWQ6
SFHMLSDVLALVVAL

SLC30A1

41

Q9Y6M5
EMLDIFVHQLLVLVV

TMEM45A

146

Q9NWC5
MLLLLLSIIVLHVAV

PMP22

1

Q01453
SLILLLVLAYALHML

ATP6AP1L

156

Q52LC2
AILLVMEGLSAFLHA

TCIRG1

786

Q13488