Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	PWWP	PSIP1 NSD1 HDGFL2 HDGF	2.01e-06	20	87	4	SM00293
Domain	PWWP	PSIP1 NSD1 HDGFL2 HDGF	3.63e-06	23	87	4	PF00855
Domain	PWWP_dom	PSIP1 NSD1 HDGFL2 HDGF	3.63e-06	23	87	4	IPR000313
Domain	PWWP	PSIP1 NSD1 HDGFL2 HDGF	4.35e-06	24	87	4	PS50812
Domain	LEDGF	PSIP1 HDGFL2	2.14e-05	2	87	2	PF11467
Domain	LEDGF	PSIP1 HDGFL2	2.14e-05	2	87	2	IPR021567
Domain	GABAAb_rcpt	GABRB1 GABRB2	6.42e-05	3	87	2	IPR002289
Domain	Chaprnin_Cpn60	HSPD1 CCT3	7.56e-04	9	87	2	IPR001844
Domain	Ubox_domain	RBBP6 PPIL2	9.42e-04	10	87	2	IPR003613
Domain	C2_dom	PREB PRKCA UNC13C RIMS1 DNAJC6	1.02e-03	164	87	5	IPR000008
Domain	TUDOR	TDRD10 TDRD1	1.88e-03	14	87	2	PF00567
Domain	-	HSPD1 CCT3	1.88e-03	14	87	2	1.10.560.10
Domain	GROEL-like_equatorial	HSPD1 CCT3	1.88e-03	14	87	2	IPR027413
Domain	Cpn60/TCP-1	HSPD1 CCT3	2.17e-03	15	87	2	IPR002423
Domain	Cpn60_TCP1	HSPD1 CCT3	2.17e-03	15	87	2	PF00118
Domain	-	HSPD1 CCT3	2.17e-03	15	87	2	3.50.7.10
Domain	GroEL-like_apical_dom	HSPD1 CCT3	2.17e-03	15	87	2	IPR027409
Domain	DS_RBD	STRBP SON	4.25e-03	21	87	2	PS50137
Domain	GABAA/Glycine_rcpt	GABRB1 GABRB2	5.09e-03	23	87	2	IPR006028
Domain	TUDOR	TDRD10 TDRD1	5.09e-03	23	87	2	PS50304
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	H1-10 URB1 SPATS2L PSIP1 CCT3 RBBP6 RRS1 STRBP RBMS2 NAF1 NUFIP2 CHD2 HSD17B10 PRKDC ANKHD1 MYEF2 SON HNRNPR	3.06e-12	807	91	18	22681889
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	HSPD1 RGPD2 FLNC STRN3 MYH6 PSIP1 CCT3 RRS1 STRBP AHNAK SLC44A2 ANKRD26 CHD2 FGFR1 RIMS1 PRKDC TAF4 KIAA2012 HDGFL2 RAI1 HNRNPR BAHCC1	1.50e-11	1442	91	22	35575683
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	HSPD1 H1-10 CAAP1 PSIP1 RBBP6 RRS1 STRBP RBMS2 AHNAK NUFIP2 NSD1 HSD17B10 PRKDC TAF4 HDGFL2 RAI1 SON HNRNPR	4.75e-11	954	91	18	36373674
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	FLNC CAAP1 URB1 SPATS2L RRS1 STRBP RBMS2 AHNAK NUFIP2 ANKRD26 PPIL2 HSD17B10 ANKHD1 SRPRB SON HNRNPR	6.46e-11	724	91	16	36232890
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	H1-10 FLNC URB1 CCT3 RRS1 STRBP AHNAK NUFIP2 NSD1 CHD2 PRKDC ANKHD1 MYEF2 RAI1 SON	1.59e-10	653	91	15	22586326
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	HSPD1 FLNC URB1 SPATS2L CCT3 RRS1 STRBP AHNAK UFD1 NUFIP2 PPIL2 HSD17B10 PRKDC LAP3 SON HDGF HNRNPR	7.24e-10	989	91	17	36424410
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	FLNC PSIP1 RBBP6 AHNAK PAFAH1B1 NUFIP2 APEH HDGFL2 LAP3 SON HDGF	8.22e-09	399	91	11	35987950
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	HSPD1 H1-10 FLNC URB1 PSIP1 CCT3 RRS1 STRBP AHNAK PRKCA HSD17B10 PRKDC SRPRB MYEF2 SON HNRNPR	9.36e-09	1024	91	16	24711643
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	HSPD1 ACSL1 H1-10 FLNC URB1 CCT3 RRS1 AHNAK PAFAH1B1 UFD1 PRKCA CHD2 PRKDC ANKHD1 SRPRB MYEF2 SON HNRNPR	1.19e-08	1353	91	18	29467282
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	HSPD1 FLNC CAAP1 NPTX1 PSIP1 RBBP6 RRS1 CHD9 PPIL2 CHD2 PRKDC ZC3H6 MYEF2 SON HNRNPR	1.35e-07	1082	91	15	38697112
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	HSPD1 FLNC CCT3 AHNAK PRKCA AKT1 HSD17B10 PRKDC SRPRB	1.38e-07	312	91	9	37120454
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HSPD1 STRN3 PSIP1 CCT3 RBBP6 RRS1 AHNAK NAF1 NUFIP2 ANKRD26 PRKDC ANKHD1 HDGFL2 SON	1.45e-07	934	91	14	33916271
Pubmed	Identification of the cAMP-dependent protein kinase and protein kinase C phosphorylation sites within the major intracellular domains of the beta 1, gamma 2S, and gamma 2L subunits of the gamma-aminobutyric acid type A receptor.	GABRB1 GABRB2 PRKCA	1.73e-07	5	91	3	1321150
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	HSPD1 METTL1 H1-10 FLNC STRN3 CCT3 AHNAK NAF1 PAFAH1B1 UFD1 APEH HSD17B10 PRKDC HDGFL2 LAP3 HDGF HNRNPR	2.05e-07	1455	91	17	22863883
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	HSPD1 PREB H1-10 URB1 PSIP1 RBBP6 AHNAK NSD1 CHD2 PRKDC TAF4 HDGFL2 SRPRB RAI1 SON HNRNPR	2.31e-07	1294	91	16	30804502
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	HSPD1 H1-10 PSIP1 CCT3 RRS1 NUFIP2 PRKDC TAF4 HDGFL2 HNRNPR	2.50e-07	441	91	10	31239290
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GABRB1 GABRB2 HSPD1 PREB RGPD2 STRN3 AMER2 RABGAP1L NUFIP2 ADGRB3 PRKCA HSD17B10 RIMS1 SRPRB MYEF2	2.61e-07	1139	91	15	36417873
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	HSPD1 H1-10 FLNC STRN3 CCT3 AHNAK PAFAH1B1 NUFIP2 HSD17B10 PRKDC ANKHD1 HDGFL2 LAP3 HDGF HNRNPR	2.91e-07	1149	91	15	35446349
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	HSPD1 H1-10 CAAP1 CCT3 RBBP6 RRS1 AHNAK ECHDC1 CHD2 HSD17B10 PRKDC TAF4 SRPRB LAP3 SON HNRNPR	2.96e-07	1318	91	16	30463901
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PREB STRN3 CAAP1 URB1 SPATS2L TBC1D10A RBBP6 RRS1 NUFIP2 NSD1 CHD2 HSD17B10 TAF4 ANKHD1 HDGFL2 MYEF2 SON	3.06e-07	1497	91	17	31527615
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	HSPD1 H1-10 PSIP1 CCT3 RRS1 NUFIP2 HSD17B10 PRKDC ANKHD1 MYEF2 SON HNRNPR	3.67e-07	714	91	12	28302793
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HSPD1 H1-10 PSIP1 CCT3 AHNAK NAF1 UFD1 PPIL2 HSD17B10 PRKDC ANKHD1 HDGFL2 SRPRB SON HDGF HNRNPR	7.58e-07	1415	91	16	28515276
Pubmed	HIV-1 integration: an interplay between HIV-1 integrase, cellular and viral proteins.	HSPD1 PSIP1 PRKDC	9.61e-07	8	91	3	15875659
Pubmed	Model of full-length HIV-1 integrase complexed with viral DNA as template for anti-HIV drug design.	HSPD1 PSIP1 PRKDC	9.61e-07	8	91	3	16075307
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	HSPD1 H1-10 CAAP1 PSIP1 CCT3 RBBP6 AHNAK NUFIP2 PPIL2 PRKDC TAF4 SON HNRNPR	1.15e-06	949	91	13	36574265
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	HSPD1 H1-10 CCT3 AHNAK UFD1 APEH PRKDC SRPRB LAP3 MYEF2 HDGF HNRNPR	1.26e-06	803	91	12	36517590
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	HSPD1 H1-10 FLNC PSIP1 CCT3 DYNC2H1 AHNAK UFD1 TDRD10 HSD17B10 PRKDC MYEF2	1.32e-06	807	91	12	30575818
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	H1-10 SPATS2L CCT3 RBBP6 RRS1 NAF1 NUFIP2 HSD17B10 MYEF2 SON HNRNPR	1.64e-06	678	91	11	30209976
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	HSPD1 PREB RGPD2 CAAP1 CCT3 RBBP6 NAF1 NUFIP2 HSD17B10 SRPRB MYEF2	2.26e-06	701	91	11	30196744
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	HSPD1 H1-10 SPATS2L CCT3 STRBP AHNAK HNRNPR	3.87e-06	245	91	7	35652658
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	HSPD1 FLNC CCT3 AHNAK NUFIP2 HSD17B10 PRKDC SON HNRNPR	4.62e-06	477	91	9	31300519
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	HSPD1 FLNC CCT3 AHNAK TAF4 TDRD1 LAP3	5.57e-06	259	91	7	31162944
Pubmed	Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.	PSIP1 HDGFL2	6.77e-06	2	91	2	16337983
Pubmed	PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival.	AKT1 PRKDC	6.77e-06	2	91	2	18439899
Pubmed	Increased apoptosis in human knee osteoarthritis cartilage related to the expression of protein kinase B and protein kinase Cα in chondrocytes.	PRKCA AKT1	6.77e-06	2	91	2	22532149
Pubmed	No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.	GABRB1 GABRB2	6.77e-06	2	91	2	12196556
Pubmed	Course of Brugia malayi infection in C57BL/6J NOS2 +/+ and -/- mice.	PRKDC NOS2	6.77e-06	2	91	2	11426950
Pubmed	DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair.	AKT1 PRKDC	6.77e-06	2	91	2	33404607
Pubmed	GABAB1 and GABAB2 receptor subunits co-expressed in cultured human RPE cells regulate intracellular Ca2+ via Gi/o-protein and phospholipase C pathways.	GABRB1 GABRB2	6.77e-06	2	91	2	25241062
Pubmed	DNA-dependent protein kinase-mediated phosphorylation of protein kinase B requires a specific recognition sequence in the C-terminal hydrophobic motif.	AKT1 PRKDC	6.77e-06	2	91	2	19144640
Pubmed	Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guérin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity.	PRKDC NOS2	6.77e-06	2	91	2	17982083
Pubmed	Protein kinase B phosphorylates AHNAK and regulates its subcellular localization.	AHNAK AKT1	6.77e-06	2	91	2	11535620
Pubmed	Regulation of the Bcas1 and Baiap3 transcripts in the subthalamic nucleus in mice recovering from MPTP toxicity.	ADGRB3 BCAS1	6.77e-06	2	91	2	21514331
Pubmed	Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase.	AKT1 PRKDC	6.77e-06	2	91	2	15262962
Pubmed	DNA-PK mediates AKT activation and apoptosis inhibition in clinically acquired platinum resistance.	AKT1 PRKDC	6.77e-06	2	91	2	22131882
Pubmed	LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells.	PSIP1 HDGFL2	6.77e-06	2	91	2	31616795
Pubmed	Cholesterol regulates contractility and inotropic response to β2-adrenoceptor agonist in the mouse atria: Involvement of Gi-protein-Akt-NO-pathway.	AKT1 NOS2	6.77e-06	2	91	2	27170493
Pubmed	iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation.	AKT1 NOS2	6.77e-06	2	91	2	36585107
Pubmed	HRP-2 determines HIV-1 integration site selection in LEDGF/p75 depleted cells.	PSIP1 HDGFL2	6.77e-06	2	91	2	23046603
Pubmed	Immunohistochemical analysis of inducible nitric oxide synthase (iNOS) and heat shock proteins (HSPs) in ameloblastomas.	HSPD1 NOS2	6.77e-06	2	91	2	12406306
Pubmed	Identification of the LEDGF/p75 HIV-1 integrase-interaction domain and NLS reveals NLS-independent chromatin tethering.	PSIP1 HDGFL2	6.77e-06	2	91	2	15797927
Pubmed	Interaction of HRP-2 isoforms with HDGF: chromatin binding of a specific heteromer.	HDGFL2 HDGF	6.77e-06	2	91	2	22212508
Pubmed	Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA double-strand break repair.	AKT1 PRKDC	6.77e-06	2	91	2	18644989
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD2 STRN3 CCT3 NUFIP2 ADGRB3 NSD1 PRKCA RIMS1 TAF4 DNAJC6 MYEF2 RAI1	8.04e-06	963	91	12	28671696
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	HSPD1 H1-10 PSIP1 CCT3 RBBP6 RRS1 AHNAK PRKDC SON HNRNPR	8.23e-06	652	91	10	31180492
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	HSPD1 H1-10 RBBP6 RRS1 NUFIP2 PRKDC TAF4 ANKHD1 MYEF2 HNRNPR	8.56e-06	655	91	10	35819319
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	CAAP1 PSIP1 RBBP6 STRBP PPIL2 PRKDC HDGFL2	9.91e-06	283	91	7	30585729
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	FLNC SPATS2L CCT3 RBMS2 AHNAK PAFAH1B1 APEH PRKCA HSD17B10 PRKDC HDGFL2 LAP3 SON HDGF	1.24e-05	1367	91	14	32687490
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PSIP1 CCT3 RBBP6 AHNAK UFD1 CHD9 CHD2 PRKDC TAF4 HDGFL2 SON HDGF	1.34e-05	1014	91	12	32416067
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	HSPD1 FLNC PSIP1 CCT3 RABGAP1L ADGRB3 HSD17B10 PRKDC ZNF804A HDGFL2 HDGF	1.35e-05	847	91	11	35235311
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	GABRB2 HSPD1 CCT3 TBC1D10A DYNC2H1 AHNAK PAFAH1B1 SLC44A2 PRKCA ADGRV1 LAP3 SLC3A1	1.37e-05	1016	91	12	19056867
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	HSPD1 RBBP6 RRS1 STRBP AHNAK RABGAP1L HSD17B10 PRKDC SRPRB	1.38e-05	547	91	9	37267103
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	HSPD1 H1-10 FLNC CCT3 NUFIP2 HSD17B10 PRKDC TAF4 HNRNPR	1.46e-05	551	91	9	34728620
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	HSPD1 PREB H1-10 FLNC PSIP1 RBBP6 AHNAK PAFAH1B1 NUFIP2 CHD2 PRKDC SRPRB HNRNPR	1.49e-05	1203	91	13	29180619
Pubmed	Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.	HSPD1 CAAP1 SPATS2L PSIP1 CCT3 RRS1 NUFIP2 LAP3 MYEF2 HNRNPR	1.59e-05	704	91	10	32994395
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	HSPD1 PREB CCT3 AHNAK NUFIP2 ANKRD26 HSD17B10 PRKDC SRPRB HDGF	1.67e-05	708	91	10	39231216
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	HSPD1 H1-10 SLC25A20 SPATS2L CCT3 PRKDC ANKHD1 HDGFL2 SRPRB HNRNPR	1.74e-05	711	91	10	33022573
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	H1-10 CAAP1 PSIP1 RBBP6 RRS1 STRBP NAF1 MYEF2 SON HNRNPR	1.78e-05	713	91	10	29802200
Pubmed	Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors.	PCP2 ADGRB3 RIMS1 RAI1	1.91e-05	60	91	4	32027825
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HSPD1 H1-10 URB1 PSIP1 CCT3 DYNC2H1 RRS1 HSD17B10 PRKDC ANKHD1 SRPRB LAP3 HDGF HNRNPR	1.97e-05	1425	91	14	30948266
Pubmed	Versican accumulation drives Nos2 induction and aortic disease in Marfan syndrome via Akt activation.	AKT1 NOS2	2.03e-05	3	91	2	38177536
Pubmed	Nitric oxide synthase and breast cancer: role of TIMP-1 in NO-mediated Akt activation.	AKT1 NOS2	2.03e-05	3	91	2	22957045
Pubmed	N-Glycosylation of GABAA receptor subunits is altered in Schizophrenia.	GABRB1 GABRB2	2.03e-05	3	91	2	23917429
Pubmed	Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.	PSIP1 HDGFL2	2.03e-05	3	91	2	33477970
Pubmed	Single-nucleotide polymorphisms inside microRNA target sites influence the susceptibility to type 2 diabetes.	ACSL1 FABP2	2.03e-05	3	91	2	23303383
Pubmed	DNA-PKcs-SIN1 complexation mediates low-dose X-ray irradiation (LDI)-induced Akt activation and osteoblast differentiation.	AKT1 PRKDC	2.03e-05	3	91	2	25264192
Pubmed	SG2NA enhances cancer cell survival by stabilizing DJ-1 and thus activating Akt.	STRN3 AKT1	2.03e-05	3	91	2	26022125
Pubmed	DNA-PKcs/AKT1 inhibits epithelial-mesenchymal transition during radiation-induced pulmonary fibrosis by inducing ubiquitination and degradation of Twist1.	AKT1 PRKDC	2.03e-05	3	91	2	38760896
Pubmed	Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase.	PSIP1 HDGFL2	2.03e-05	3	91	2	15371438
Pubmed	Suppression of DNA-PKcs enhances FGF-2 dependent human endothelial cell proliferation via negative regulation of Akt.	AKT1 PRKDC	2.03e-05	3	91	2	19781633
Pubmed	Common polymorphism in the phosphatase PHLPP2 results in reduced regulation of Akt and protein kinase C.	PRKCA AKT1	2.03e-05	3	91	2	19324870
Pubmed	RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis.	AKT1 PRKDC	2.03e-05	3	91	2	23135917
Pubmed	GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.	GABRB1 GABRB2	2.03e-05	3	91	2	7893750
Pubmed	Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum.	GABRB1 GABRB2	2.03e-05	3	91	2	1282920
Pubmed	Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme.	PRKCA AKT1	2.03e-05	3	91	2	18622039
Pubmed	Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host.	PRKDC NOS2	2.03e-05	3	91	2	21576322
Pubmed	Attenuated nephritis in inducible nitric oxide synthase knockout C57BL/6 mice and pulmonary hemorrhage in CB17 SCID and recombination activating gene 1 knockout C57BL/6 mice infected with Leptospira interrogans.	PRKDC NOS2	2.03e-05	3	91	2	21576342
Pubmed	In vivo analysis of protein kinase B (PKB)/Akt regulation in DNA-PKcs-null mice reveals a role for PKB/Akt in DNA damage response and tumorigenesis.	AKT1 PRKDC	2.03e-05	3	91	2	18757368
Pubmed	The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.	FLNC PRKCA	2.03e-05	3	91	2	12704190
Pubmed	Protein kinase Cepsilon activates protein kinase B/Akt via DNA-PK to protect against tumor necrosis factor-alpha-induced cell death.	AKT1 PRKDC	2.03e-05	3	91	2	16785234
Pubmed	FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell.	AKT1 FGFR1	2.03e-05	3	91	2	26993162
Pubmed	Hepatoma-derived growth factor belongs to a gene family in mice showing significant homology in the amino terminus.	HDGFL2 HDGF	2.03e-05	3	91	2	9299445
Pubmed	Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.	GABRB1 GABRB2	2.03e-05	3	91	2	11085308
Pubmed	GABAA receptor beta subunit mRNA expression in the human alcoholic brain.	GABRB1 GABRB2	2.03e-05	3	91	2	15337300
Pubmed	LEDGF gene silencing impairs the tumorigenicity of prostate cancer DU145 cells by abating the expression of Hsp27 and activation of the Akt/ERK signaling pathway.	PSIP1 AKT1	2.03e-05	3	91	2	22647853
Pubmed	Activated cdc42-associated kinase is up-regulated in non-small-cell lung cancer and necessary for FGFR-mediated AKT activation.	AKT1 FGFR1	2.03e-05	3	91	2	25945695
Pubmed	Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.	HSPD1 H1-10 FLNC CCT3 NUFIP2 HSD17B10 PRKDC SRPRB SON HNRNPR	2.05e-05	725	91	10	27025967
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	HSPD1 H1-10 CCT3 RBBP6 NUFIP2 APEH CHD9 PPIL2 HSD17B10 PRKDC ZC3H6 HDGF HNRNPR	2.18e-05	1247	91	13	27684187
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	HSPD1 H1-10 PSIP1 CCT3 RBBP6 RRS1 NUFIP2 MYEF2 SON HNRNPR	2.20e-05	731	91	10	29298432
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	HSPD1 H1-10 SPATS2L PSIP1 CCT3 RBMS2 ANKRD26 PRSS23 ANKHD1 MYEF2	2.22e-05	732	91	10	34732716
Interaction	SMC5 interactions	HSPD1 H1-10 CAAP1 PSIP1 RBBP6 RRS1 STRBP RBMS2 AHNAK NUFIP2 NSD1 HSD17B10 PRKDC TAF4 HDGFL2 RAI1 SON HNRNPR	3.07e-07	1000	89	18	int:SMC5
Interaction	SIRT7 interactions	H1-10 FLNC URB1 CCT3 RRS1 STRBP AHNAK NUFIP2 NSD1 CHD2 PRKDC ANKHD1 MYEF2 RAI1 SON	8.42e-07	744	89	15	int:SIRT7
Interaction	AGR2 interactions	HSPD1 H1-10 FLNC PSIP1 CCT3 DYNC2H1 AHNAK UFD1 NSD1 TDRD10 HSD17B10 PRKDC NOS2 MYEF2 FABP2 HDGF	2.92e-06	934	89	16	int:AGR2
Interaction	OBSL1 interactions	HSPD1 H1-10 FLNC URB1 SPATS2L PSIP1 CCT3 RRS1 STRBP AHNAK HSD17B10 PRKDC MYEF2 SON HNRNPR	8.87e-06	902	89	15	int:OBSL1
Interaction	FGF11 interactions	STRN3 CCT3 STRBP CHD9 ANKHD1 SRPRB SON	1.03e-05	170	89	7	int:FGF11
Interaction	MECP2 interactions	HSPD1 FLNC CAAP1 URB1 NPTX1 PSIP1 RBBP6 RRS1 NUFIP2 NSD1 CHD9 PPIL2 CHD2 PRKDC ZC3H6 MYEF2 SON HNRNPR	1.10e-05	1287	89	18	int:MECP2
Interaction	BAP1 interactions	HSPD1 H1-10 FLNC STRN3 CCT3 AHNAK PAFAH1B1 NUFIP2 MEIOB PRKCA AKT1 HSD17B10 PRKDC ANKHD1 HDGFL2 LAP3 HDGF HNRNPR	1.45e-05	1314	89	18	int:BAP1
Interaction	CIT interactions	HSPD1 H1-10 FLNC URB1 PSIP1 CCT3 RBBP6 DYNC2H1 RRS1 STRBP AHNAK NUFIP2 CHD2 PRKDC ADGRV1 OSGIN2 HDGFL2 SON HNRNPR	1.50e-05	1450	89	19	int:CIT
Interaction	VARS1 interactions	CCT3 AHNAK UFD1 PRKCA POC5 ANKHD1 HDGFL2 LAP3	1.98e-05	260	89	8	int:VARS1
Interaction	MYCN interactions	HSPD1 H1-10 SPATS2L PSIP1 CCT3 RBBP6 RRS1 STRBP RBMS2 NUFIP2 CHD2 PRKDC HDGFL2 MYEF2 RAI1 SON HDGF HNRNPR	2.62e-05	1373	89	18	int:MYCN
Interaction	KCNA3 interactions	HSPD1 PREB CCT3 RBBP6 AHNAK NUFIP2 ANKRD26 CHD9 CHD2 HSD17B10 RIMS1 PRKDC SRPRB HDGF	2.67e-05	871	89	14	int:KCNA3
Interaction	RICTOR interactions	HSPD1 RGPD2 FLNC STRN3 CCT3 RRS1 AHNAK PRKCA AKT1 HSD17B10 PRKDC ANKHD1 SRPRB	2.77e-05	759	89	13	int:RICTOR
Interaction	H1-2 interactions	H1-10 URB1 RRS1 STRBP AHNAK PAFAH1B1 NSD1 APEH PRKCA PRKDC ZC3H6 HDGF	3.56e-05	666	89	12	int:H1-2
Interaction	RBM39 interactions	HSPD1 H1-10 CAAP1 PSIP1 CCT3 RRS1 NUFIP2 HSD17B10 PRKDC ANKHD1 LAP3 MYEF2 SON HDGF HNRNPR	4.77e-05	1042	89	15	int:RBM39
Interaction	H2AC4 interactions	H1-10 FLNC STRBP CHD9 CHD2 HSD17B10 PRKDC TAF4 ANKHD1 RAI1	7.85e-05	506	89	10	int:H2AC4
Interaction	MIR19A interactions	RBBP6 STRBP RBMS2 NUFIP2 HNRNPR	8.12e-05	100	89	5	int:MIR19A
Interaction	NAA40 interactions	HSPD1 STRN3 PSIP1 CCT3 RBBP6 RRS1 AHNAK NAF1 NUFIP2 ANKRD26 PRKDC ANKHD1 HDGFL2 SON	9.34e-05	978	89	14	int:NAA40
Interaction	NUP43 interactions	HSPD1 H1-10 PSIP1 CCT3 RBBP6 RRS1 NSD1 CHD9 TAF4 CSMD3 SON	9.52e-05	625	89	11	int:NUP43
Interaction	MAPT interactions	HSPD1 H1-10 FLNC NPTX1 CCT3 AHNAK PAFAH1B1 UFD1 NUFIP2 APEH PRKCA AKT1 HSD17B10 RIMS1 HNRNPR	1.07e-04	1119	89	15	int:MAPT
Interaction	ITGB3 interactions	FLNC PRKCA AKT1 FGFR1 PRKDC SON	1.07e-04	170	89	6	int:ITGB3
Interaction	CBX3 interactions	HSPD1 PSIP1 RBBP6 RRS1 NSD1 CHD9 PPIL2 TAF4 HDGFL2 LAP3 HDGF	1.27e-04	646	89	11	int:CBX3
Interaction	FLT1 interactions	URB1 STRBP PAFAH1B1 FGFR1 PRKDC SRPRB	1.43e-04	179	89	6	int:FLT1
Interaction	PRNP interactions	HSPD1 FLNC STRN3 AMER2 NPTX1 RBMS2 ECHDC1 NAF1 APEH POC5 BCAS1 TAF4 ZC3H6 MYEF2 HDGF	1.55e-04	1158	89	15	int:PRNP
Interaction	MAGEB2 interactions	URB1 SPATS2L RBBP6 RRS1 STRBP NSD1 MYEF2 HDGF	1.56e-04	349	89	8	int:MAGEB2
Interaction	NHERF1 interactions	HSPD1 TBC1D10A PRKCA AKT1 FGFR1 NOS2	1.61e-04	183	89	6	int:NHERF1
Interaction	SCARNA22 interactions	HSPD1 PSIP1 STRBP PRKDC HNRNPR	1.77e-04	118	89	5	int:SCARNA22
Interaction	PINK1 interactions	HSPD1 ACSL1 FLNC CCT3 AHNAK NUFIP2 AKT1 HSD17B10 PRKDC SON HNRNPR	1.97e-04	679	89	11	int:PINK1
Interaction	KIF20A interactions	HSPD1 FLNC URB1 PSIP1 RBBP6 DYNC2H1 RRS1 AHNAK RABGAP1L NUFIP2 CHD2 PRKDC SON HNRNPR	2.00e-04	1052	89	14	int:KIF20A
Interaction	PFKFB1 interactions	PRKCA AKT1 NOS2	2.01e-04	26	89	3	int:PFKFB1
Interaction	NPM1 interactions	H1-10 FLNC URB1 SPATS2L PSIP1 RRS1 NUFIP2 NSD1 PRKCA CCDC80 AKT1 PRKDC NOS2 SON HNRNPR	2.31e-04	1201	89	15	int:NPM1
Interaction	CENPA interactions	H1-10 URB1 PSIP1 NSD1 PPIL2 PRKDC HDGFL2 RAI1	2.63e-04	377	89	8	int:CENPA
Interaction	TNIP1 interactions	HSPD1 H1-10 CAAP1 PSIP1 CCT3 RBBP6 AHNAK NUFIP2 APEH PPIL2 PRKDC TAF4 SON HDGF HNRNPR	2.67e-04	1217	89	15	int:TNIP1
Interaction	DCAF4 interactions	HSPD1 SPATS2L CCT3 RBBP6 RRS1 RBMS2 HSD17B10 LAP3	2.68e-04	378	89	8	int:DCAF4
Interaction	DDX23 interactions	CAAP1 URB1 RBBP6 RRS1 NAF1 PPIL2 CHD2 HDGFL2 HNRNPR	2.69e-04	480	89	9	int:DDX23
Interaction	TIAM2 interactions	UFD1 PRKCA PRKDC	2.80e-04	29	89	3	int:TIAM2
Interaction	PSIP1 interactions	SPATS2L PSIP1 RRS1 HDGFL2 SON HDGF	2.97e-04	205	89	6	int:PSIP1
Interaction	MIR29B1 interactions	STRBP RBMS2 MYEF2 HNRNPR	3.07e-04	73	89	4	int:MIR29B1
Interaction	USP14 interactions	HSPD1 FLNC PSIP1 AHNAK UFD1 PRKDC HDGFL2 SRPRB HNRNPR	3.09e-04	489	89	9	int:USP14
Interaction	WDR5 interactions	HSPD1 H1-10 SLC25A20 SPATS2L PSIP1 CCT3 PAFAH1B1 PRKDC TAF4 ANKHD1 HDGFL2 SRPRB HDGF HNRNPR	3.19e-04	1101	89	14	int:WDR5
Interaction	BRD3 interactions	CAAP1 PSIP1 RBBP6 RRS1 NSD1 CHD9 TAF4 RAI1 SON	3.32e-04	494	89	9	int:BRD3
Interaction	PRC1 interactions	HSPD1 H1-10 FLNC URB1 PSIP1 CCT3 RBBP6 RRS1 STRBP AHNAK PRKDC SON HNRNPR	3.33e-04	973	89	13	int:PRC1
Interaction	DDRGK1 interactions	HSPD1 PREB H1-10 CAAP1 SPATS2L PSIP1 CCT3 RRS1 STRBP FGFR1 HSD17B10 PRKDC SRPRB MYEF2 HNRNPR	3.52e-04	1249	89	15	int:DDRGK1
Interaction	CHMP4B interactions	HSPD1 H1-10 FLNC URB1 STRBP AHNAK HSD17B10 PRKDC PRSS23 SON HNRNPR	3.53e-04	727	89	11	int:CHMP4B
Cytoband	2q33.1	HSPD1 SPATS2L KIAA2012	1.46e-04	51	91	3	2q33.1
GeneFamily	PWWP domain containing	PSIP1 NSD1 HDGF	3.32e-05	22	52	3	1147
GeneFamily	Chaperonins	HSPD1 CCT3	8.32e-04	15	52	2	587
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRB1 GABRB2	1.34e-03	19	52	2	563
GeneFamily	RNA binding motif containing	RBMS2 TDRD10 MYEF2 HNRNPR	3.26e-03	213	52	4	725
GeneFamily	Tudor domain containing	TDRD10 TDRD1	5.07e-03	37	52	2	780
Coexpression	BRUINS_UVC_RESPONSE_LATE	GABRB1 PREB METTL1 MYH6 NPTX1 SLC25A20 AHNAK ECHDC1 PRKCA CCDC80 PPIL2 RIMS1 PRSS23 HDGFL2 SRPRB	6.14e-06	1136	89	15	M2247
Coexpression	BRUINS_UVC_RESPONSE_LATE	GABRB1 PREB METTL1 MYH6 NPTX1 SLC25A20 AHNAK ECHDC1 PRKCA CCDC80 PPIL2 RIMS1 PRSS23 HDGFL2 SRPRB	1.16e-05	1198	89	15	MM1062
Coexpression	SANA_RESPONSE_TO_IFNG_DN	HSPD1 CCT3 FGFR1 PRSS23 HDGF	1.20e-05	87	89	5	M9583
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH6 AHNAK PAFAH1B1 NUFIP2 NSD1 CHD9 CCDC80	7.63e-08	176	91	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	RV-16._Neuronal\|World / Chamber and Cluster_Paper	AHNAK ADGRB3 PRKCA OSGIN2 DNAJC6 FAM135B	6.30e-07	149	91	6	3a2f8c4173dcf9e3f8d3b8ffddbc597098adf7a9
ToppCell	facs-Brain_Non-Myeloid-Cerebellum\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 STRBP PCP2 UNC13C RIMS1 FAM135B	2.22e-06	185	91	6	c083a4974590b9ed3ecafedd3e9cdebc5047fe39
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 ARHGEF33 STRBP PCP2 UNC13C RIMS1	2.29e-06	186	91	6	a1ab273b01971d6a892912560d387685dd657179
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 ARHGEF33 STRBP PCP2 UNC13C RIMS1	2.37e-06	187	91	6	ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPTX1 ARHGEF33 STRBP PCP2 UNC13C RIMS1	2.52e-06	189	91	6	3d838da870623a6a278ddc8e6cedca85d9877e50
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STRBP AHNAK CCDC80 BCAS1 PRSS23 KIAA2012	3.29e-06	198	91	6	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPATS2L GBP7 AHNAK BCAS1 FAM135B	1.33e-05	148	91	5	f58804d24fe524b42b5090c8658050ea4b14793e
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_D\|E18.5-samps / Age Group, Lineage, Cell class and subclass	GABRB2 FLNC AMER2 SPATS2L PRSS23	1.38e-05	149	91	5	dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell	RV-16._Neuronal\|RV / Chamber and Cluster_Paper	ADGRB3 PRKCA OSGIN2 DNAJC6 FAM135B	1.56e-05	153	91	5	bed8bbf5c5cbfbf46a816066da472c3fdddecb5d
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GABRB2 AMER2 CCDC80 UNC13C DNAJC6	2.32e-05	166	91	5	545f6c91102568791443717e522f89cb3bd1a070
ToppCell	LA-16._Neuronal\|World / Chamber and Cluster_Paper	AHNAK ADGRB3 PRKCA DNAJC6 FAM135B	2.45e-05	168	91	5	2fd1fd2a16ac1c5eb028f93cc3a2477c7747693e
ToppCell	LA-16._Neuronal\|LA / Chamber and Cluster_Paper	AHNAK ADGRB3 PRKCA DNAJC6 FAM135B	2.45e-05	168	91	5	c55bbfbde8bb954f1cb9af82007bdd1f8070fee3
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB1 TBC1D10A PRKCA ADGRV1 MYEF2	3.15e-05	177	91	5	d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	AMER2 ANKRD26 PRKCA CHD2 CSMD3	3.15e-05	177	91	5	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	URB1 CHD2 RIMS1 ADGRV1 RAI1	3.32e-05	179	91	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	AHNAK ADGRB3 PRKCA DNAJC6 FAM135B	3.41e-05	180	91	5	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 STRBP PCP2 UNC13C RIMS1	3.41e-05	180	91	5	f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell	RA-16._Neuronal\|World / Chamber and Cluster_Paper	AHNAK ADGRB3 PRKCA DNAJC6 FAM135B	3.50e-05	181	91	5	7d22a43f887e0747f0cb87ba364ff27905ee6eec
ToppCell	droplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPD1 METTL1 RRS1 NAF1 LAP3	3.69e-05	183	91	5	92ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCell	droplet-Marrow-nan-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPD1 METTL1 RRS1 NAF1 LAP3	3.69e-05	183	91	5	24db9cc717e651586317c6a8e03a3401651273c1
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 NPTX1 PCP2 UNC13C RIMS1	3.99e-05	186	91	5	d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	H1-10 AHNAK NUFIP2 ADGRV1 CSMD3	3.99e-05	186	91	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 NPTX1 PCP2 UNC13C RIMS1	4.31e-05	189	91	5	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	NS-critical-d_16-33-Epithelial-Secretory-diff\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AHNAK CCDC80 RIMS1 PRSS23 NOS2	4.64e-05	192	91	5	02b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB2 NPTX1 PCP2 UNC13C RIMS1	4.76e-05	193	91	5	5fb7808dd971c1cc64c2bd4f8f1de646fb2d77f4
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	URB1 RIMS1 BCAS1 PRSS23 NOS2	4.87e-05	194	91	5	e0228f593c3493175962a4817500d4337ddc4e88
ToppCell	droplet-Marrow-BM-1m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSL1 CCT3 STRBP AKT1 HDGF	4.99e-05	195	91	5	637b06ef3967b03f7165d102d316e8b7161a817d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 NPTX1 STRBP RIMS1 CSMD3	4.99e-05	195	91	5	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	COVID-19_Severe\|World / Disease condition and Cell class	HSPD1 H1-10 PSIP1 UFD1 HNRNPR	5.12e-05	196	91	5	450ac2aff89c5ca73b8bfbc80663e03be066931f
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 STRBP ADGRB3 RIMS1 CSMD3	5.12e-05	196	91	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	PSIP1 RBBP6 AHNAK ANKRD26 CHD2	5.24e-05	197	91	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	CV-Mild-2\|CV / Virus stimulation, Condition and Cluster	HSPD1 METTL1 CCT3 RRS1 SRPRB	5.24e-05	197	91	5	dc1cfba2ee66c62b53accefbfce3025cd760524a
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 STRBP ADGRB3 RIMS1 CSMD3	5.37e-05	198	91	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRB2 STRBP ADGRB3 RIMS1 CSMD3	5.37e-05	198	91	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	CV-Moderate-2\|CV / Virus stimulation, Condition and Cluster	HSPD1 METTL1 CCT3 RRS1 SRPRB	5.50e-05	199	91	5	2d98424a5247e87f98095c11fb945289092a9d75
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AHNAK CCDC80 RIMS1 BCAS1 PRSS23	5.50e-05	199	91	5	1e693d7bb481bf03a943b460a69787229625d7b1
ToppCell	CD8+_Memory_T_cell-CV-2\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	HSPD1 METTL1 CCT3 RRS1 SRPRB	5.50e-05	199	91	5	1e33d8e2e0d6a54ef6e2e13f986e19fd209275a8
ToppCell	CV-Moderate-2\|Moderate / Virus stimulation, Condition and Cluster	HSPD1 METTL1 CCT3 RRS1 SRPRB	5.50e-05	199	91	5	70d6f2a328eec4cb2cecb7cd85859fba9e15c9c8
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPD1 H1-10 CCT3 RBBP6 AHNAK	5.50e-05	199	91	5	f3cc3cda38f78d1d12d865df339d93c5fecf19f2
ToppCell	CV-Mild-2\|Mild / Virus stimulation, Condition and Cluster	HSPD1 METTL1 CCT3 RRS1 SRPRB	5.50e-05	199	91	5	d88cc07053a852e6c468538a0a851ffa09f97a0d
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|megakaryocytic / Lineage and Cell class	HSPD1 H1-10 CCT3 PRKDC HNRNPR	5.50e-05	199	91	5	99a65887d3c8a2cde26693dd74404b101bba9d58
ToppCell	Int-URO-Myeloid-cDC2\|Int-URO / Disease, Lineage and Cell Type	HSPD1 SPATS2L CCT3 ECHDC1 LAP3	5.50e-05	199	91	5	7bbeda66f522b803f85be65d1a81555e12585efc
ToppCell	Sepsis-Int-URO-Myeloid-cDC2\|Int-URO / Disease, condition lineage and cell class	HSPD1 SPATS2L CCT3 ECHDC1 LAP3	5.63e-05	200	91	5	dd8ac355b3b0394fda005789f9f2ff6560a02dac
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	GBP7 ZNF683 PRSS23 BAHCC1	6.40e-05	105	91	4	8f31edf4183587f5b53941475453c5aa49f10bbd
Disease	schizophrenia (implicated_via_orthology)	AKT1 RIMS1 CSMD3 ZNF804A	5.20e-05	68	88	4	DOID:5419 (implicated_via_orthology)
Disease	bipolar disorder	NPTX1 SPATS2L SLC44A2 PRKCA WFDC5 FGFR1 RIMS1 ANKHD1 ZNF804A	5.69e-05	577	88	9	MONDO_0004985
Disease	paraplegia (biomarker_via_orthology)	AKT1 NOS2	8.74e-05	5	88	2	DOID:607 (biomarker_via_orthology)
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD2	1.83e-04	7	88	2	DOID:0050834 (implicated_via_orthology)
Disease	Endotoxemia	HSPD1 NOS2	2.43e-04	8	88	2	C0376618
Disease	autistic disorder (is_implicated_in)	GABRB1 GABRB2 HSPD1	2.70e-04	42	88	3	DOID:12849 (is_implicated_in)
Disease	Schizophrenia	GABRB1 GABRB2 PAFAH1B1 UFD1 NUFIP2 PRKCA AKT1 FGFR1 ZNF804A RAI1	3.00e-04	883	88	10	C0036341
Disease	Adenocarcinoma of lung (disorder)	RRS1 STRBP AKT1 HSD17B10 PRKDC	3.87e-04	206	88	5	C0152013
Disease	Sarcomatoid Renal Cell Carcinoma	HSPD1 AHNAK CSMD3 ZNF804A	5.94e-04	128	88	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	HSPD1 AHNAK CSMD3 ZNF804A	5.94e-04	128	88	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	HSPD1 AHNAK CSMD3 ZNF804A	5.94e-04	128	88	4	C1266044
Disease	Papillary Renal Cell Carcinoma	HSPD1 AHNAK CSMD3 ZNF804A	5.94e-04	128	88	4	C1306837
Disease	Renal Cell Carcinoma	HSPD1 AHNAK CSMD3 ZNF804A	5.94e-04	128	88	4	C0007134
Disease	Fulminant Hepatic Failure with Cerebral Edema	GABRB1 PRKDC	6.71e-04	13	88	2	C0751197
Disease	Hepatic Stupor	GABRB1 PRKDC	6.71e-04	13	88	2	C0751198
Disease	Hepatic Encephalopathy	GABRB1 PRKDC	6.71e-04	13	88	2	C0019151
Disease	Hepatic Coma	GABRB1 PRKDC	6.71e-04	13	88	2	C0019147
Disease	hepatic encephalopathy (biomarker_via_orthology)	GABRB1 NOS2	9.00e-04	15	88	2	DOID:13413 (biomarker_via_orthology)
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	HSPD1 AHNAK CSMD3 ZNF804A	1.02e-03	148	88	4	C0279702
Disease	Autistic Disorder	GABRB1 NSD1 RIMS1 CSMD3 NOS2	1.12e-03	261	88	5	C0004352
Disease	autism spectrum disorder (implicated_via_orthology)	PREB CHD9 CHD2 RIMS1	1.13e-03	152	88	4	DOID:0060041 (implicated_via_orthology)
Disease	Drug-Induced Liver Disease	ACSL1 CCT3 ECHDC1 CCDC80 PRKDC LAP3	1.34e-03	404	88	6	C0860207
Disease	Drug-Induced Acute Liver Injury	ACSL1 CCT3 ECHDC1 CCDC80 PRKDC LAP3	1.34e-03	404	88	6	C3658290
Disease	Hepatitis, Toxic	ACSL1 CCT3 ECHDC1 CCDC80 PRKDC LAP3	1.34e-03	404	88	6	C0019193
Disease	Chemically-Induced Liver Toxicity	ACSL1 CCT3 ECHDC1 CCDC80 PRKDC LAP3	1.34e-03	404	88	6	C4279912
Disease	Chemical and Drug Induced Liver Injury	ACSL1 CCT3 ECHDC1 CCDC80 PRKDC LAP3	1.34e-03	404	88	6	C4277682
Disease	Hepatitis, Drug-Induced	ACSL1 CCT3 ECHDC1 CCDC80 PRKDC LAP3	1.34e-03	404	88	6	C1262760
Disease	bipolar disorder, schizophrenia, response to lithium ion	SPATS2L ZNF804A	1.61e-03	20	88	2	GO_0010226, MONDO_0004985, MONDO_0005090
Disease	dilated cardiomyopathy	FLNC PRKCA	1.61e-03	20	88	2	EFO_0000407
Disease	Epilepsy, Cryptogenic	GABRB2 AKT1 CHD2	1.91e-03	82	88	3	C0086237
Disease	Awakening Epilepsy	GABRB2 AKT1 CHD2	1.91e-03	82	88	3	C0751111
Disease	Aura	GABRB2 AKT1 CHD2	1.91e-03	82	88	3	C0236018
Disease	cigarettes per day measurement	SLC25A20 RABGAP1L NUFIP2 SLC44A2 MEIOB ZNF804A	2.01e-03	438	88	6	EFO_0006525
Disease	TEMPS-A questionnaire	DYNC2H1 ADGRB3	2.52e-03	25	88	2	EFO_0004783
Disease	Hypertrophic obstructive cardiomyopathy	HSPD1 MYH6	2.52e-03	25	88	2	C4551472
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	GABRB1 GABRB2 XYLT1 SPATS2L NUFIP2 FGFR1 PRKDC FAM135B	2.71e-03	801	88	8	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	methionine measurement	ADGRV1 ANKHD1	2.73e-03	26	88	2	EFO_0009771
Disease	Neurodevelopmental Disorders	GABRB2 CHD2 RIMS1	2.74e-03	93	88	3	C1535926
Disease	alcohol use disorder (implicated_via_orthology)	PRKCA ZNF683 AKT1 UNC13C	2.80e-03	195	88	4	DOID:1574 (implicated_via_orthology)
Disease	age-related hearing impairment	XYLT1 CAAP1 PAFAH1B1 NSD1 CSMD3	2.88e-03	324	88	5	EFO_0005782
Disease	lissencephaly (implicated_via_orthology)	PAFAH1B1 NOS2	2.94e-03	27	88	2	DOID:0050453 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
VVGSKGDRKKLPAGN	TDRD1	96	Q9BXT4
NDKEKDKAGGRLPSG	nan	36	Q8N814
KDPKQRLGGGSEDAK	AKT1	386	P31749
DRGEAGSLQKGPKDF	BAHCC1	201	Q9P281
LLKKNGRSENGKGEP	AMER2	166	Q8N7J2
SRGFKLFPGKDNSNK	CSMD3	456	Q7Z407
TNFPGLQKKGEEDQK	ADGRB3	136	O60242
LGKDSGLKPFEQVKG	ACSL1	641	P33121
EGNKLIGKFKRTDNG	FABP2	86	P12104
FKVQLKNPKGGAEIG	ADGRV1	3621	Q8WXG9
KKKNGNATGEDFCGP	ARHGEF33	826	A8MVX0
KAKKQGFDLNVPGGE	AHNAK	5036	Q09666
NKQPEGLELKQGKGE	CAAP1	236	Q9H8G2
KAPGFGDNRKNQLKD	HSPD1	301	P10809
PLAGAADGKEKNIGN	ANKRD26	436	Q9UPS8
RGTKDGIQNAFLKGP	CEP20	116	Q96NB1
KKGGKTEQDGYQKPT	CCDC80	586	Q76M96
PDKLGGKQRAAFKSG	RAI1	1081	Q7Z5J4
KISEKGLSFENGKGP	NSD1	1121	Q96L73
KKYGTNPSNGEKLDG	PPIL2	71	Q13356
FQPVGSKDGAQKRAG	PCP2	91	Q8IVA1
KFADGGPKKRQNQGK	RBMS2	216	Q15434
KEEFTSGGPLGQKRD	PAFAH1B1	76	P43034
EKGQKDNRPGDKFQL	NPTX1	216	Q15818
GKANKPGDVVRAKNG	LAP3	341	P28838
GKTDVKGFPDRKNIG	MEIOB	31	Q8N635
GDCPGNGEKLKKSLF	NOS2	596	P35228
TNNKKEEYGPGVQGK	POC5	381	Q8NA72
KGEKGQPQELGRRFA	INKA2	191	Q9NTI7
YNEIPKNGKGSTRKG	MEPE	396	Q9NQ76
LNEKQRFPSKGKSQG	MEPE	421	Q9NQ76
QRGFGKFGELLKPQK	LRRIQ4	521	A6NIV6
GGPANLEAIAKKGKF	ECHDC1	291	Q9NTX5
NGSFKLNRKKLEGGG	H1-10	111	Q92522
PEGKPKKANIRDNGD	FLNC	1581	Q14315
EKFGKPNKRKGFSEG	HDGF	71	P51858
GKRKADGYNQPDSKR	HNRNPR	571	O43390
GGAFPNRKADLSDKQ	KIAA2012	326	Q0VF49
FGFGLGKKLQQKHPE	SLC25A20	91	O43772
NKLAGKNKGFPLGCT	GBP7	56	Q8N8V2
FFGKGPQKKGASKQD	GABRB1	331	P18505
FGRGPQRQKKAAEKA	GABRB2	331	P47870
DKYGKPNKRKGFNEG	HDGFL2	66	Q7Z4V5
DLPNSGGEAQAKKLG	HSD17B10	41	Q99714
DGKGNFSPVPKDRDK	RABGAP1L	286	Q5R372
TNGDKNFESGPRIKK	RBBP6	176	Q7Z6E9
RKKTPGLSEQNGKGA	RIMS1	271	Q86UR5
PEFGAAINKGKLRGK	OSGIN2	286	Q9Y236
KGYGGRQKLPDNLKQ	DYNC2H1	1796	Q8NCM8
KQGLAQKRPFDGEDG	CHD9	2361	Q3L8U1
QLKENASEGKGPGKR	CHD2	1191	O14647
LKNGKEFKPDHRIGG	FGFR1	191	P11362
LSGQGFNAHKDKKGP	DNAJC6	786	O75061
GEFCGQKGTKNENKP	SLC44A2	71	Q8IWA5
DIPKGKGKQFDAQGH	FAM135B	846	Q49AJ0
PEKRQQSLGGFFKGL	BCAS1	546	O75363
GLNQKPEKGENGIRF	SLC15A1	476	P46059
KIANGVPNSKGDKGN	MINAR1	566	Q9UPX6
QKNKLKEPGGGSFRD	TAF4	816	O00268
GGESPKQKGQEIKRS	STRN3	226	Q13033
APAQLGKKGKEFEFS	SRPRB	221	Q9Y5M8
PKNKGGAKNQEASLG	SPATS2L	481	Q9NUQ6
LRQKFEKAKLGPAGN	PRKCA	301	P17252
DKNSGAGEKKGPNRN	MYEF2	86	Q9P2K5
KDPNFKGFSGAGEKL	RGPD2	981	P0DJD1
GKNGVLEEQKSPGFK	TDRD10	16	Q5VZ19
KKALEFQDLGNKGQP	NSUN7	451	Q8NE18
KPKFKDGGRGANDST	PRSS23	196	O95084
FKDSNKDGNGDLKGI	SLC3A1	131	Q07837
HKKKGDDQSRQGGAP	CCT3	526	P49368
EVDGQKFRGAGPNKK	STRBP	546	Q96SI9
IGDRGKKDNANANKG	MYH6	201	P13533
PQSKHKELRAGKGNG	REELD1	396	A0A1B0GV85
DDKKGQKRSDGPPAA	URB1	526	O60287
LRKAGGTGPGEEKQF	APEH	106	P13798
QKADKNKINGEPRGG	ANKHD1	1571	Q8IWZ3
GKEAKKAGPGFHRQL	C10orf126	141	Q8N4M7
EKYGKPNKRKGFNEG	PSIP1	66	O75475
EKAGSKEQGPRQRKG	PREB	106	Q9HCU5
GSQLPAVFGRKKGEK	WFDC5	16	Q8TCV5
KLEQQEKGKGHTFPG	XYLT1	196	Q86Y38
SGAKLGDPRLQKNFD	ZC3H6	956	P61129
AGGNGLKKNFLEKSP	UNC13C	1991	Q8NB66
ETPKKKTGYGELNGN	NUFIP2	86	Q7Z417
RGSGKKRKFQPLFGD	RRS1	246	Q15050
GKKRLGLPGDEVDNK	PRKDC	2701	P78527
SGNRLDGKKKGVEPS	UFD1	231	Q92890
GGKVKLQQNPGKFDE	TBC1D10A	126	Q9BXI6
GEGLGKNKEGNKEPI	SON	2321	P18583
GKKVLRNGGKNFPAI	METTL1	241	Q9UBP6
KDKLGKQPERAGEGA	ZNF683	131	Q8IZ20
IKGVFRGPLSKNGNK	ZNF804A	21	Q7Z570
IQGRKKLKSEFNEPG	NAF1	331	Q96HR8