Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	neurexin family protein binding	NLGN4Y NLGN1 NLGN4X NLGN2	4.79e-06	16	147	4	GO:0042043
GeneOntologyBiologicalProcess	presynaptic membrane assembly	NLGN4Y NLGN1 NLGN4X NLGN2	4.63e-07	10	144	4	GO:0097105
GeneOntologyBiologicalProcess	postsynaptic membrane assembly	NLGN4Y NLGN1 NLGN4X NLGN2	7.24e-07	11	144	4	GO:0097104
GeneOntologyBiologicalProcess	presynaptic membrane organization	NLGN4Y NLGN1 NLGN4X NLGN2	1.55e-06	13	144	4	GO:0097090
GeneOntologyBiologicalProcess	neuron cell-cell adhesion	NLGN4Y NLGN1 NLGN4X NLGN2	3.89e-06	16	144	4	GO:0007158
GeneOntologyBiologicalProcess	membrane biogenesis	NLGN4Y VPS4B NLGN1 ZNF750 NLGN4X NLGN2	1.21e-05	73	144	6	GO:0044091
GeneOntologyBiologicalProcess	postsynaptic membrane organization	NLGN4Y NLGN1 SLC30A1 NLGN4X NLGN2	4.44e-05	56	144	5	GO:0001941
GeneOntologyBiologicalProcess	postsynaptic density protein 95 clustering	NLGN1 SLC30A1 NLGN2	5.28e-05	11	144	3	GO:0097119
GeneOntologyBiologicalProcess	vesicle localization	MAP2 MYO19 VPS4B NLGN1 AP3M1 UNC13C NLGN2 TRAPPC9 CHP1	6.12e-05	247	144	9	GO:0051648
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	CACNA1A MAP1A NLGN4Y NLGN1 SLC30A1 NLGN4X FCGR2B GPR158 SYNGR1 KMT2A AFDN UNC13C NLGN2 SLC24A1 ATP2A2	6.38e-05	663	144	15	GO:0050804
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	CACNA1A MAP1A NLGN4Y NLGN1 SLC30A1 NLGN4X FCGR2B GPR158 SYNGR1 KMT2A AFDN UNC13C NLGN2 SLC24A1 ATP2A2	6.48e-05	664	144	15	GO:0099177
GeneOntologyBiologicalProcess	membrane assembly	NLGN4Y VPS4B NLGN1 NLGN4X NLGN2	8.47e-05	64	144	5	GO:0071709
GeneOntologyBiologicalProcess	dendrite development	CACNA1A MAP1A MAP2 NLGN1 SLC30A1 FCGR2B TET1 AFDN NLGN2 ALK	1.25e-04	335	144	10	GO:0016358
GeneOntologyBiologicalProcess	territorial aggressive behavior	NLGN4Y NLGN4X	1.45e-04	3	144	2	GO:0002124
GeneOntologyBiologicalProcess	establishment of vesicle localization	MAP2 MYO19 VPS4B NLGN1 AP3M1 UNC13C TRAPPC9 CHP1	1.81e-04	224	144	8	GO:0051650
GeneOntologyCellularComponent	symmetric, GABA-ergic, inhibitory synapse	NLGN4Y NLGN4X NLGN2	1.41e-06	4	149	3	GO:0098983
GeneOntologyCellularComponent	histone deacetylase complex	NRIP1 SIN3B JMJD1C RCOR1 TET1 CFDP1	3.26e-05	85	149	6	GO:0000118
GeneOntologyCellularComponent	inhibitory synapse	NLGN4Y NLGN1 NLGN4X NLGN2	6.72e-05	31	149	4	GO:0060077
GeneOntologyCellularComponent	symmetric synapse	NLGN4Y NLGN4X NLGN2	9.63e-05	13	149	3	GO:0032280
GeneOntologyCellularComponent	excitatory synapse	NLGN4Y NLGN1 NLGN4X AFDN UNC13C NLGN2	1.19e-04	107	149	6	GO:0060076
GeneOntologyCellularComponent	primary dendrite	MAP1A MAP2	3.00e-04	4	149	2	GO:0150001
GeneOntologyCellularComponent	glycinergic synapse	NLGN4Y NLGN4X NLGN2	3.70e-04	20	149	3	GO:0098690
GeneOntologyCellularComponent	postsynaptic specialization membrane	NLGN4Y NLGN1 SLC30A1 NLGN4X GPR158 AFDN NLGN2	6.08e-04	201	149	7	GO:0099634
GeneOntologyCellularComponent	asymmetric, glutamatergic, excitatory synapse	NLGN4Y NLGN1 NLGN4X	6.44e-04	24	149	3	GO:0098985
GeneOntologyCellularComponent	chromatin	NRIP1 SIN3B SMARCA5 LRWD1 ZEB1 INCENP XRCC1 LHX6 JMJD1C USP44 PPARGC1A ARRB1 NFATC2 HOXD12 BASP1 TET1 CFDP1 FER ANKRD11 ZFHX2 TGIF2LX KAT6B	8.11e-04	1480	149	22	GO:0000785
GeneOntologyCellularComponent	dendritic branch	MAP1A MAP2	1.04e-03	7	149	2	GO:0044307
Domain	Nlgn	NLGN4Y NLGN1 NLGN4X NLGN2	1.93e-08	5	149	4	IPR000460
Domain	Carboxylesterase_B_CS	NLGN4Y NLGN1 NLGN4X NLGN2	2.63e-06	13	149	4	IPR019819
Domain	CARBOXYLESTERASE_B_2	NLGN4Y NLGN1 NLGN4X NLGN2	3.66e-06	14	149	4	PS00941
Domain	COesterase	NLGN4Y NLGN1 NLGN4X NLGN2	3.66e-06	14	149	4	PF00135
Domain	CarbesteraseB	NLGN4Y NLGN1 NLGN4X NLGN2	3.66e-06	14	149	4	IPR002018
Domain	NLGN4	NLGN4Y NLGN4X	6.32e-05	2	149	2	IPR030025
Domain	WTX	AMER1 AMER2	1.89e-04	3	149	2	PF09422
Domain	DUF4592	CRACD CRACDL	1.89e-04	3	149	2	IPR028030
Domain	DUF4592	CRACD CRACDL	1.89e-04	3	149	2	PF15262
Domain	Uncharacterised_FAM123	AMER1 AMER2	1.89e-04	3	149	2	IPR019003
Pubmed	Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.	NLGN4Y NLGN1 NLGN4X NLGN2	1.84e-09	5	154	4	37865312
Pubmed	Synapse formation: if it looks like a duck and quacks like a duck ...	NLGN4Y NLGN1 NLGN4X NLGN2	1.84e-09	5	154	4	10996085
Pubmed	The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?	NLGN4Y NLGN1 NLGN4X NLGN2	5.51e-09	6	154	4	21838267
Pubmed	Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.	NLGN4Y NLGN1 NLGN4X NLGN2	5.51e-09	6	154	4	29724786
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FNBP1 XRN2 SMARCA5 LRWD1 ZEB1 TCOF1 CAST DAB2 REXO1 SETD2 UTP18 YLPM1 KMT2A AFDN KAT6B DNMBP SPEN ATP2A2	1.16e-08	774	154	18	15302935
Pubmed	Human transcription factor protein interaction networks.	SIN3B XRN2 SMARCA5 ZEB1 YBX1 RC3H1 XRCC1 RBM28 LHX6 JMJD1C RCOR1 SALL2 BASP1 YLPM1 CFDP1 KMT2A EBNA1BP2 SPEN ATP2A2 HSPA4 TOP1 TRAPPC9 PRRC2B PYGO1	2.03e-08	1429	154	24	35140242
Pubmed	Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.	NLGN4Y NLGN1 NLGN4X NLGN2	2.55e-08	8	154	4	30871858
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	LRWD1 MAP1A RC3H1 CAST APC C16orf96 PRKRA TDRD3 BASP1 YLPM1 FER EBNA1BP2 DNMBP SPEN ATP2A2 TOP1 PRRC2B	2.63e-08	724	154	17	36232890
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	XRN2 SMARCA5 INCENP TCOF1 RBM28 PRKRA UTP18 YLPM1 KMT2A AFDN EBNA1BP2 SPEN ATP2A2 HSPA4 TOP1 PRRC2B	3.87e-08	653	154	16	22586326
Pubmed	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	ZEB1 TACC2 TDRD1 AP3M1 JMJD1C GPR158 TET1 DNAJC12 POLL KAT6B DNMBP BTRC CFAP46	4.72e-08	415	154	13	16385451
Pubmed	Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.	NLGN4Y NLGN4X NLGN2	8.51e-08	3	154	3	21282647
Pubmed	SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.	NLGN4Y NLGN1 NLGN4X NLGN2	1.19e-07	11	154	4	32973045
Pubmed	Behavioral phenotypes of genetic mouse models of autism.	NLGN4Y NLGN1 NLGN4X NLGN2	1.19e-07	11	154	4	26403076
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CACNA1A FKBP15 MAP1A MAP2 YBX1 TCEAL5 APC TACC2 SLC30A1 AP3M1 YARS1 PRKRA AMER2 GPR158 BASP1 SYNGR1 AFDN TMEM35A ATP2A2 BTRC	1.71e-07	1139	154	20	36417873
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA1A SIN3B APC AP3M1 PRKRA TDRD3 GPR158 FER HSPA4 TOP1 BTRC TRAPPC9 PRRC2B	2.23e-07	475	154	13	31040226
Pubmed	Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.	XRN2 FAM234A ZNF280D NEIL2 CAST ZCCHC2 LHX6 MTMR10 NUAK2 PRKRA USP44 CRACD TDRD3 INTS14 TXLNB CFAP46	2.52e-07	750	154	16	11230166
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	XRN2 SMARCA5 INCENP YBX1 CAST XRCC1 RBM28 JMJD1C SETD2 YLPM1 ANKRD11 KMT2A AFDN EBNA1BP2 SPEN ATP2A2 ALK TOP1	2.63e-07	954	154	18	36373674
Pubmed	Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.	NLGN4Y NLGN4X NLGN2	3.39e-07	4	154	3	12669065
Pubmed	Homodimerization and isoform-specific heterodimerization of neuroligins.	NLGN4Y NLGN4X NLGN2	3.39e-07	4	154	3	22671294
Pubmed	Analysis of four neuroligin genes as candidates for autism.	NLGN4Y NLGN1 NLGN4X	3.39e-07	4	154	3	16077734
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NRIP1 XRN2 MAP1A TCOF1 APC TACC2 ZCCHC2 YARS1 TDRD3 SETD2 SALL2 DNMBP SPEN PRRC2B	4.03e-07	588	154	14	38580884
Pubmed	Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.	NLGN4Y NLGN1 NLGN4X NLGN2	4.86e-07	15	154	4	18227507
Pubmed	Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.	NLGN1 NLGN4X NLGN2	8.46e-07	5	154	3	15620359
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	FKBP15 SIN3B SMARCA5 MAP1A TCOF1 CAST TACC2 CRACD TDRD3 SETD2 YLPM1 CFDP1 KMT2A EBNA1BP2 HSPA4 TOP1 PRRC2B	9.46e-07	934	154	17	33916271
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CDK17 AMER1 MAP2 COBLL1 APC NUAK2 FSIP2 STOX2 TET1 ANKRD11 KMT2A AFDN AKAP11 DNMBP TSSK1B TRAPPC9	1.54e-06	861	154	16	36931259
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	FNBP1 XRCC1 JMJD1C SETD2 KMT2A SPEN ATP2A2 TOP1	1.71e-06	183	154	8	36129980
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 SIN3B RC3H1 COBLL1 DELE1 ZCCHC2 JMJD1C REXO1 SETD2 PTCD1 NLGN2 TRAPPC9	2.24e-06	493	154	12	15368895
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	SIN3B XRN2 LRWD1 JMJD1C CFDP1 KMT2A SPEN	2.39e-06	134	154	7	25452129
Pubmed	Genomic analysis of mouse retinal development.	SIN3B TCEAL3 VTN MAP2 YBX1 MDM1 TCEAL5 APC TACC2 PRKRA SALL2 SCG2 MCM9 KMT2A TMEM35A SLC24A1 PRRC2B	2.57e-06	1006	154	17	15226823
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	XRN2 SMARCA5 LRWD1 VTN TCOF1 YBX1 XRCC1 RBM28 PAFAH1B3 YLPM1 AFDN EBNA1BP2 SPEN ATP2A2 HSPA4 TOP1 RAB5C	3.26e-06	1024	154	17	24711643
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	SIN3B SMARCA5 LRWD1 ZNF280D INCENP XRCC1 JMJD1C FSIP2 CFDP1 KMT2A EBNA1BP2 SPEN TOP1	3.46e-06	608	154	13	36089195
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NRIP1 XRN2 DCAF6 TCOF1 KIAA0319L RTL10 APC MTMR10 YARS1 ZBED5 PRKRA ARRB1 SCG2 YLPM1 PPP1R16B AFDN ATP2A2 TOP1 BTRC	4.46e-06	1285	154	19	35914814
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SIN3B XRN2 SMARCA5 LRWD1 TCOF1 XRCC1 RBM28 JMJD1C SETD2 RCOR1 INTS14 UTP18 YLPM1 ANKRD11 KMT2A EBNA1BP2 SPEN ATP2A2 TOP1	4.93e-06	1294	154	19	30804502
Pubmed	DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.	NLGN4Y NLGN1 NLGN4X NLGN2	5.12e-06	26	154	4	34848499
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CACNA1A CDK17 MAP1A MAP2 APC AP3M1 YARS1 NUAK2 PRKRA CRACD CRACDL SYNGR1 KMT2A AFDN ATP2A2 HSPA4 TOP1 TRAPPC9 RAB5C PRRC2B	5.66e-06	1431	154	20	37142655
Pubmed	The functional interactome landscape of the human histone deacetylase family.	SIN3B MDM1 RBM28 RCOR1 UTP18 YLPM1 ANKRD11 EBNA1BP2 TOP1	6.17e-06	289	154	9	23752268
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SIN3B SMARCA5 TCOF1 CAST JMJD1C SETD2 TET1 YLPM1 KMT2A AFDN SPEN PRRC2B	6.68e-06	549	154	12	38280479
Pubmed	Binding of neuroligins to PSD-95.	NLGN1 NLGN4X NLGN2	7.01e-06	9	154	3	9278515
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	XRN2 SMARCA5 INCENP YBX1 AGGF1 TACC2 XRCC1 RBM28 PRKRA TDRD3 UTP18 MCM9 EBNA1BP2 TOP1	7.80e-06	759	154	14	35915203
Pubmed	Role of Elavl-like RNA-binding protein in retinal development and signal transduction.	NLGN4Y NLGN4X NLGN2 GJA10	1.06e-05	31	154	4	39307290
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SIN3B LRWD1 APC XRCC1 CRACD TDRD3 SETD2 ARRB1 NFATC2 PTCD1 CRACDL ANKRD11 PALM3 KMT2A AFDN DNMBP SPEN ATP2A2 RAB5C CHP1	1.10e-05	1497	154	20	31527615
Pubmed	DNA cloning using in vitro site-specific recombination.	FAM234A ZNF280D NEIL2 CAST APC ZCCHC2 LHX6 MTMR10 NUAK2 USP44 TDRD3 RCOR1 INTS14 TXLNB	1.29e-05	794	154	14	11076863
Pubmed	The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.	NRIP1 JMJD1C PPARGC1A	1.37e-05	11	154	3	36613751
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	XRN2 TCOF1 YBX1 RC3H1 RBM28 PRKRA TDRD3 UTP18 PTCD1 YLPM1 EBNA1BP2 SPEN TOP1 PRRC2B	1.55e-05	807	154	14	22681889
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	XRN2 TCOF1 NEIL2 OAS3 RCOR1 UTP18 YLPM1 DNMBP SPEN ATP2A2	1.58e-05	410	154	10	26949251
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FNBP1 XRN2 SMARCA5 TCOF1 COBLL1 DAB2 APC TACC2 UTP18 AFDN SPEN	1.63e-05	503	154	11	16964243
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	CAST DAB2 XRCC1 TDRD1 GHR FCGR2B SCG2 SLC24A1 SPEN	1.73e-05	329	154	9	17474147
Pubmed	Proteomic analysis of human Nop56p-associated pre-ribosomal ribonucleoprotein complexes. Possible link between Nop56p and the nucleolar protein treacle responsible for Treacher Collins syndrome.	TCOF1 YBX1 RBM28 EBNA1BP2 TOP1	1.76e-05	72	154	5	12777385
Pubmed	Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.	AMER1 APC BTRC	1.82e-05	12	154	3	22682247
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	NRIP1 DAB2 XRCC1 SETD2 IGFBP6 USHBP1 SCG2 KAT6B SPEN HSPA4 PRRC2B PDZD4	1.84e-05	608	154	12	16713569
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NRIP1 SIN3B ZEB1 ZNF280D VPS4B APC JMJD1C RCOR1 SALL2 TET1	1.86e-05	418	154	10	34709266
Pubmed	Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.	TET1 KMT2A	1.95e-05	2	154	2	23100278
Pubmed	LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23).	TET1 KMT2A	1.95e-05	2	154	2	12124344
Pubmed	Loss of SETD2 Induces a Metabolic Switch in Renal Cell Carcinoma Cell Lines toward Enhanced Oxidative Phosphorylation.	PPARGC1A SETD2	1.95e-05	2	154	2	30406665
Pubmed	Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis.	APC SETD2	1.95e-05	2	154	2	28825595
Pubmed	SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia.	SETD2 KMT2A	1.95e-05	2	154	2	29249820
Pubmed	AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane.	AMER1 APC	1.95e-05	2	154	2	17925383
Pubmed	MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.	SETD2 KMT2A	1.95e-05	2	154	2	29777171
Pubmed	Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.	NLGN4Y NLGN4X	1.95e-05	2	154	2	23183221
Pubmed	Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.	NLGN4Y NLGN4X	1.95e-05	2	154	2	24855039
Pubmed	Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.	NLGN4Y NLGN4X	1.95e-05	2	154	2	37001827
Pubmed	The MicroRNA miR-696 is regulated by SNARK and reduces mitochondrial activity in mouse skeletal muscle through Pgc1α inhibition.	NUAK2 PPARGC1A	1.95e-05	2	154	2	33812060
Pubmed	The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells.	NEIL2 APC	1.95e-05	2	154	2	32872214
Pubmed	Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.	NLGN1 NLGN2	1.95e-05	2	154	2	19889999
Pubmed	Stimulation of NEIL2-mediated oxidized base excision repair via YB-1 interaction during oxidative stress.	YBX1 NEIL2	1.95e-05	2	154	2	17686777
Pubmed	Peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is a metabolic regulator of intestinal epithelial cell fate.	APC PPARGC1A	1.95e-05	2	154	2	21467224
Pubmed	Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons.	NLGN1 NLGN2	1.95e-05	2	154	2	10892652
Pubmed	Amer2 protein is a novel negative regulator of Wnt/β-catenin signaling involved in neuroectodermal patterning.	APC AMER2	1.95e-05	2	154	2	22128170
Pubmed	NRIP1/RIP140 siRNA-mediated attenuation counteracts mitochondrial dysfunction in Down syndrome.	NRIP1 PPARGC1A	1.95e-05	2	154	2	24698981
Pubmed	SNF2H interacts with XRCC1 and is involved in repair of H2O2-induced DNA damage.	SMARCA5 XRCC1	1.95e-05	2	154	2	27268481
Pubmed	Deficiency of nuclear receptor interaction protein leads to cardiomyopathy by disrupting sarcomere structure and mitochondrial respiration.	NRIP1 DCAF6	1.95e-05	2	154	2	31629737
Pubmed	Unusually rapid evolution of Neuroligin-4 in mice.	NLGN4Y NLGN4X	1.95e-05	2	154	2	18434543
Pubmed	The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group.	TET1 KMT2A	1.95e-05	2	154	2	19144982
Pubmed	βTrCP controls GH receptor degradation via two different motifs.	GHR BTRC	1.95e-05	2	154	2	22034227
Pubmed	NLGN1 and NLGN2 in the prefrontal cortex: their role in memory consolidation and strengthening.	NLGN1 NLGN2	1.95e-05	2	154	2	29278843
Pubmed	NRIP, a novel calmodulin binding protein, activates calcineurin to dephosphorylate human papillomavirus E2 protein.	NRIP1 DCAF6	1.95e-05	2	154	2	21543494
Pubmed	First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia.	TET1 KMT2A	1.95e-05	2	154	2	24323992
Pubmed	Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.	NLGN4Y NLGN4X	1.95e-05	2	154	2	37080762
Pubmed	Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.	NLGN4Y NLGN4X	1.95e-05	2	154	2	29106499
Pubmed	Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.	NLGN4Y NLGN4X	1.95e-05	2	154	2	26456829
Pubmed	Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.	NLGN4Y NLGN4X	1.95e-05	2	154	2	24104404
Pubmed	MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia.	KMT2A AFDN	1.95e-05	2	154	2	24695851
Pubmed	A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.	NLGN4Y NLGN4X	1.95e-05	2	154	2	32243781
Pubmed	Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.	NLGN4Y NLGN4X	1.95e-05	2	154	2	22989184
Pubmed	Y-box binding protein 1 enhances DNA topoisomerase 1 activity and sensitivity to camptothecin via direct interaction.	YBX1 TOP1	1.95e-05	2	154	2	25539742
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	XRN2 YBX1 MYO19 DAB2 OAS3 XRCC1 RBM28 PRKRA CRACD UTP18 BASP1 KMT2A EBNA1BP2 ATP2A2 HSPA4 BTRC TRAPPC9 PRRC2B CHP1	2.20e-05	1440	154	19	30833792
Pubmed	Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.	TCOF1 XRCC1 RBM28 JMJD1C YLPM1 KMT2A KAT6B SPEN TOP1	2.30e-05	341	154	9	32971831
Pubmed	The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes.	SMARCA5 APC KMT2A	2.36e-05	13	154	3	16510874
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	SIN3B APC JMJD1C STOX2 MEIOC DNMBP PRRC2B PDZD4	2.42e-05	263	154	8	34702444
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1A FKBP15 SIN3B ZEB1 TCOF1 APC TDRD3 STOX2 RCOR1 GPR158 BASP1 YLPM1 AFDN NLGN2 PRRC2B	2.66e-05	963	154	15	28671696
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FNBP1 SIN3B SMARCA5 LRWD1 AGGF1 XRCC1 JMJD1C YARS1 CRACD SALL2 NFATC2 CFDP1 SPEN BTRC	2.99e-05	857	154	14	25609649
Pubmed	Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program.	SMARCA5 APC KMT2A	3.73e-05	15	154	3	16510875
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	XRN2 LRWD1 TCOF1 RBM28 PRKRA TDRD3 PTCD1 YLPM1 EBNA1BP2	3.82e-05	364	154	9	24778252
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SMARCA5 XRCC1 JMJD1C BASP1 YLPM1 CFDP1 SPEN TOP1	4.07e-05	283	154	8	30585729
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	CRYBG2 MDM1 ZCCHC2 JMJD1C NFATC2 KAT6B DNMBP BTRC PRRC2B	4.42e-05	371	154	9	15747579
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	AMER1 INCENP TCOF1 YBX1 KIAA0319L APC SLC30A1 UTP18 BASP1 AFDN EBNA1BP2 SPEN PRRC2B	4.56e-05	777	154	13	35844135
Pubmed	Wilms tumor suppressor WTX negatively regulates WNT/beta-catenin signaling.	AMER1 APC BTRC	5.53e-05	17	154	3	17510365
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CDK17 DCAF6 LRWD1 INCENP YBX1 APC AGGF1 TACC2 STOX2 RCOR1 ARRB1 PAFAH1B3 YLPM1 EBNA1BP2 RAB5C PRRC2B	5.78e-05	1155	154	16	20360068
Pubmed	Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus.	NLGN1 NLGN2	5.83e-05	3	154	2	22960622
Pubmed	Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.	NLGN1 NLGN2	5.83e-05	3	154	2	28607166
Interaction	CBX3 interactions	SMARCA5 LRWD1 ZEB1 AMER1 ZNF280D INCENP TCOF1 COBLL1 XRCC1 ZNF518A ZNF750 SETD2 NFATC2 CFDP1 KMT2A SPEN TOP1 PRRC2B	1.72e-06	646	151	18	int:CBX3
Interaction	NUP43 interactions	XRN2 LRWD1 ZNF280D INCENP APC RBM28 JMJD1C ZNF518A USP44 FSIP2 SETD2 SALL2 ANKRD11 KMT2A EBNA1BP2 SPEN TOP1	4.70e-06	625	151	17	int:NUP43
Interaction	H2BC21 interactions	SMARCA5 LRWD1 ZNF280D INCENP XRCC1 JMJD1C PPARGC1A RCOR1 TET1 CFDP1 FER KMT2A POLL AKAP11 KAT6B TOP1 BTRC CFAP46	4.87e-06	696	151	18	int:H2BC21
Interaction	POLR1G interactions	XRN2 INCENP TCOF1 RC3H1 XRCC1 RBM28 UTP18 ARRB1 CFDP1 ANKRD11 KMT2A EBNA1BP2 ATP2A2 TOP1	1.94e-05	489	151	14	int:POLR1G
Interaction	RBPJ interactions	FNBP1 SMARCA5 XRCC1 JMJD1C PRKRA RCOR1 CFDP1 KMT2A SPEN TOP1	2.24e-05	254	151	10	int:RBPJ
Interaction	NRXN1 interactions	MAP2 NLGN1 AMER2 GPR158 AFDN NLGN2 TMEM35A	4.86e-05	127	151	7	int:NRXN1
Interaction	CTBP1 interactions	NRIP1 DCAF6 ZEB1 APC ZNF518A ZNF750 RCOR1 NFATC2 KMT2A SPEN RAB5C PRRC2B	5.74e-05	406	151	12	int:CTBP1
Interaction	NOP10 interactions	CDK17 YBX1 RC3H1 OAS3 PRKRA ARRB1	6.32e-05	91	151	6	int:NOP10
Interaction	CUL7 interactions	XRN2 SMARCA5 LRWD1 VTN MAP1A TCOF1 YBX1 LINC01599 XRCC1 SETD2 PTCD1 PAFAH1B3 AFDN EBNA1BP2 SPEN ATP2A2 TOP1 RAB5C	6.42e-05	845	151	18	int:CUL7
Interaction	TERF2IP interactions	XRN2 ZEB1 INCENP XRCC1 SETD2 RCOR1 SALL2 PAFAH1B3 CFDP1 ANKRD11 KMT2A SPEN HSPA4 TOP1	7.21e-05	552	151	14	int:TERF2IP
Interaction	ABT1 interactions	XRN2 ZEB1 AMER1 YBX1 NAP1L5 RBM28 PRKRA UTP18 PTCD1 KMT2A SPEN RAB5C	8.48e-05	423	151	12	int:ABT1
Interaction	NRXN2 interactions	NLGN1 AFDN NLGN2	8.63e-05	12	151	3	int:NRXN2
Interaction	RCOR1 interactions	FNBP1 SIN3B SMARCA5 VPS4B APC JMJD1C ZNF750 RCOR1 SALL2 NFATC2 TET1 SPEN HSPA4	9.12e-05	494	151	13	int:RCOR1
Interaction	SUDS3 interactions	SIN3B SMARCA5 YBX1 TET1 PPP1R16B TGIF2LX HSPA4	9.43e-05	141	151	7	int:SUDS3
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	FKBP15 APC YLPM1 FER PPP1R16B AKAP11	3.85e-04	181	95	6	694
GeneFamily	Transcription elongation factor A like family	TCEAL3 TCEAL5	9.60e-04	9	95	2	1216
GeneFamily	Zinc fingers CXXC-type	TET1 KMT2A	1.74e-03	12	95	2	136
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	CACNA1A FNBP1 FKBP15 MAP2 NAP1L5 TCEAL5 APC NLGN1 FSIP2 PPARGC1A STOX2 AMER2 NLGN4X GPR158 BASP1 ZFHX2 DNAJC12 TMEM35A PRRC2B PDZD4	7.27e-06	1106	153	20	M39071
Coexpression	FORTSCHEGGER_PHF8_TARGETS_DN	SIN3B CRYBG2 DCAF6 SELENOS NAP1L5 CAST NCF2 TACC2 RBM28 SLC30A1 ZBED5 IGFBP6 FER BTRC PRRC2B CHP1	1.47e-05	783	153	16	M2488
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	PRUNE2 COBLL1 NLGN1 PPARGC1A STOX2 EBNA1BP2 HSPA4 CHP1	1.88e-07	176	154	8	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZEB1 MAP2 NLGN1 GHR PPARGC1A NLGN4X GPR158	4.96e-07	200	154	8	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZEB1 MAP2 NLGN1 GHR PPARGC1A NLGN4X GPR158	4.96e-07	200	154	8	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZEB1 MAP2 NLGN1 GHR PPARGC1A NLGN4X GPR158	4.96e-07	200	154	8	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SMARCA5 CAST OAS3 ZCCHC2 JMJD1C SETD2 ANKRD11 KMT2A	4.96e-07	200	154	8	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZEB1 MAP2 NLGN1 GHR PPARGC1A NLGN4X GPR158	4.96e-07	200	154	8	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZEB1 MAP2 NLGN1 GHR PPARGC1A NLGN4X GPR158	4.96e-07	200	154	8	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	CACNA1A ZEB1 MAP2 NLGN1 GHR PPARGC1A NLGN4X GPR158	4.96e-07	200	154	8	961858738ce35db8760c8c2e136f8369bc444ccf
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC4 MDM1 F8 GPR158 YLPM1 ZFHX2 AKAP11	2.52e-06	174	154	7	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP2 NLGN4Y SAMD15 TXLNB FCGR2B PPP1R16B DNMBP	2.52e-06	174	154	7	59ccc5a82507463e0a316ba6286cb25ec1a4091b
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	ABCC4 MAP1A COBLL1 OAS3 RBM28 RNF126 STOX2	2.72e-06	176	154	7	2049767fd591045cfcf5b1071d80798e52843f27
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PRUNE2 MAP2 NLGN1 CRACD SCG2 AKAP11 ALK	3.04e-06	179	154	7	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A PRUNE2 TCEAL3 MAP2 AMER2 SCG2 NLGN2	3.16e-06	180	154	7	9db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XRN2 SMARCA5 APC JMJD1C SETD2 ANKRD11 KMT2A	3.65e-06	184	154	7	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNA1A ZEB1 TCEAL5 STOX2 ZFHX2 AFDN KAT6B	4.21e-06	188	154	7	e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 PRUNE2 TCEAL3 SELENOS NAP1L5 SCG2 DNAJC12	4.21e-06	188	154	7	63773854bf8430fb8229edb385b953a89833d08c
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP1 SMARCA5 YBX1 CAST ZNF518A ANKRD11 AKAP11	4.67e-06	191	154	7	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 EMILIN1 GPR158 SCG2 ZFHX2 ATP2A2 PRRC2B	4.67e-06	191	154	7	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP1 SMARCA5 YBX1 CAST ZNF518A ANKRD11 AKAP11	4.67e-06	191	154	7	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRIP1 SMARCA5 YBX1 CAST ZNF518A ANKRD11 AKAP11	4.67e-06	191	154	7	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 MDM1 TACC2 GHR SCG2 ATP2A2 PRRC2B	4.83e-06	192	154	7	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_D\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	C2orf88 FNDC4 REXO1 SAMD15 PALM3 CFAP46	4.89e-06	125	154	6	9e98dcfdc768ae492f453efc08926164bbb0a909
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FNBP1 ABCC4 ZEB1 VTN NUAK2 CRACD BASP1	5.00e-06	193	154	7	7426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCell	BAL-Severe-Myeloid-cDC-cDC-cDC_10\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FNBP1 ABCC4 ZEB1 VTN NUAK2 CRACD BASP1	5.00e-06	193	154	7	a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 MDM1 TACC2 GHR SCG2 ATP2A2 PRRC2B	5.17e-06	194	154	7	92b39a935e8c577eb1123d706d168fa13cf3344c
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TCEAL3 EMILIN1 GPR158 SCG2 ZFHX2 ATP2A2	5.17e-06	194	154	7	490645bfe9ed3dac03c191c7094df01c780b377e
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 EMILIN1 GPR158 SCG2 ZFHX2 ATP2A2 PRRC2B	5.35e-06	195	154	7	bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCell	390C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FNBP1 ZEB1 VTN TCOF1 NUAK2 BASP1 AFDN	5.35e-06	195	154	7	ecf7d9856a5b507ec17c325c9a772dc5a184bc8e
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TCEAL3 EMILIN1 GPR158 SCG2 ZFHX2 ATP2A2	5.35e-06	195	154	7	58b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCell	BAL-Severe-cDC_10\|Severe / Compartment, Disease Groups and Clusters	FNBP1 DCAF6 ZEB1 VTN CRACD BASP1 PPP1R16B	6.11e-06	199	154	7	54bdadd04abaf8caa948b0177c037bc089ca07e6
ToppCell	COVID-19_Mild-Neu_2\|World / 5 Neutrophil clusters in COVID-19 patients	FAM234A AMER1 TDRD1 EMILIN1 FER TMEM35A	9.38e-06	140	154	6	b1429028c52f84127b894b93b55961badcd5246f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NAP1L5 DAB2 LHX6 EMILIN1 UNC13C CFAP46	1.80e-05	157	154	6	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	SIN3B DCAF6 RC3H1 SETD2 C19orf44 AFDN	2.46e-05	166	154	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTCHD3 RBM28 AMER2 IGFBP6 BASP1 UNC13C	2.46e-05	166	154	6	545f6c91102568791443717e522f89cb3bd1a070
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	NAP1L5 LHX6 CRACD SCG2 ALK PYGO1	2.55e-05	167	154	6	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-6\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PAPPA2 C2orf88 GHR HOXD12 TMEM35A PDZD4	2.64e-05	168	154	6	5ce3129a023a48a3d7e6b9306c1fc5addfef9675
ToppCell	Immune_cells-pro-B\|Immune_cells / Lineage and Cell class	C2orf88 RCSD1 JMJD1C CRACDL PAFAH1B3 PPP1R16B	3.01e-05	172	154	6	096636f2589fa56d15942aac96641c16fd5fa78d
ToppCell	facs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOS YARS1 TXLNB USHBP1 SCG2 SYNGR1	3.01e-05	172	154	6	a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCell	facs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOS YARS1 TXLNB USHBP1 SCG2 SYNGR1	3.01e-05	172	154	6	65b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF750 PPARGC1A NLGN4X USHBP1 SCG2 UNC13C	3.21e-05	174	154	6	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ZEB1 SLC30A1 SMTNL1 USHBP1 PPP1R16B DNMBP	3.21e-05	174	154	6	cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF750 PPARGC1A NLGN4X USHBP1 SCG2 UNC13C	3.21e-05	174	154	6	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	facs-Heart-LV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 DAB2 NCF2 NUAK2 FCGR2B BASP1	3.21e-05	174	154	6	54166a0faf748cccb6406c2c268e1e6e21caf6d0
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZNF750 PPARGC1A NLGN4X USHBP1 SCG2 UNC13C	3.21e-05	174	154	6	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF750 PPARGC1A NLGN4X USHBP1 SCG2 UNC13C	3.21e-05	174	154	6	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	facs-Heart-LV-3m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 DAB2 NCF2 NUAK2 FCGR2B BASP1	3.21e-05	174	154	6	dc8a238ec1d954bec0f8eb67c04a61734c96f5b5
ToppCell	facs-Heart-LV-3m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 DAB2 NCF2 NUAK2 FCGR2B BASP1	3.31e-05	175	154	6	5d106ef542b97f97aeb19179e3f72963ead1e82a
ToppCell	TCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3\|TCGA-Cervix / Sample_Type by Project: Shred V9	CRYBG2 VPS4B COBLL1 NUAK2 ZNF750 RCOR1	3.31e-05	175	154	6	0cc215109d9915af47e4d0a120ce2e46910715fa
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PAPPA2 ABCC4 EMILIN1 NLGN4X GPR158 ALK	3.76e-05	179	154	6	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PPARGC1A NLGN4X USHBP1 SCG2 UNC13C ALK	3.76e-05	179	154	6	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	CTRL-Myeloid-cDC\|Myeloid / Disease state, Lineage and Cell class	ZEB1 CRACD FCGR2B NFATC2 BASP1 PPP1R16B	4.13e-05	182	154	6	ee137574b8f0e684a4a7cb26226877c471cae433
ToppCell	normal-na-Lymphocytic_B-B_mem-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TCOF1 NLGN4Y COBLL1 RCSD1 FCGR2B BASP1	4.13e-05	182	154	6	ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCell	CTRL-Myeloid-cDC\|CTRL / Disease state, Lineage and Cell class	ZEB1 CRACD FCGR2B NFATC2 BASP1 PPP1R16B	4.25e-05	183	154	6	20c4d16de7e090df3556a4458f783383a26871b6
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 PRUNE2 TCEAL3 MAP2 NAP1L5 SCG2	4.39e-05	184	154	6	3da93e7d8b62463e307cc0425c47dbd3bef66799
ToppCell	IPF-Myeloid-DC_Langerhans\|Myeloid / Disease state, Lineage and Cell class	ABCC4 ZEB1 FNDC4 NFATC2 PPP1R16B AFDN	4.52e-05	185	154	6	ced17f69486591c3cbbdc852a3e82c3f3a4a30d7
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LHX6 STOX2 ARRB1 IGFBP6 UNC13C TMEM35A	4.66e-05	186	154	6	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CDK17 JMJD1C RCOR1 ANKRD11 KMT2A SPEN	4.94e-05	188	154	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 EMILIN1 SCG2 ZFHX2 ATP2A2 PRRC2B	4.94e-05	188	154	6	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	facs-Pancreas-Endocrine-24m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NAP1L5 SCG2 ZFHX2 ATP2A2 PRRC2B	5.09e-05	189	154	6	010fdd70e9d0e21b856306a29ff877776a480319
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 F8 EMILIN1 FCGR2B USHBP1 PPP1R16B	5.40e-05	191	154	6	1924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 MDM1 GHR GPR158 SCG2 ATP2A2	5.40e-05	191	154	6	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 F8 EMILIN1 FCGR2B USHBP1 PPP1R16B	5.40e-05	191	154	6	88f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 NAP1L5 SCG2 ZFHX2 ATP2A2 PRRC2B	5.40e-05	191	154	6	a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FNBP1 JMJD1C RCOR1 PTCD1 ANKRD11 TRAPPC9	5.72e-05	193	154	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	droplet-Tongue-TONGUE-1m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 LHX6 TDRD1 SYNGR1 AFDN CHP1	5.72e-05	193	154	6	55eab7d2574e9cc2ed8f08e0a7ca7cbf90fb5818
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 COBLL1 TACC2 NLGN1 PPARGC1A AFDN	5.72e-05	193	154	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	CF-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	FNBP1 COBLL1 FCGR2B BASP1 FER AKAP11	5.72e-05	193	154	6	7ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCell	facs-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TCEAL3 NAP1L5 SCG2 ZFHX2 ATP2A2	5.72e-05	193	154	6	15c86e20b97b6983410b36d308cddff56d141c98
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP2 ZNF750 ARRB1 BASP1 CRACDL SYNGR1	5.88e-05	194	154	6	0ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ABCC4 NLGN1 PPARGC1A STOX2 AFDN	5.88e-05	194	154	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	MAP1A MAP2 TCEAL5 GPR158 SCG2 PDZD4	5.88e-05	194	154	6	b6488bc3a8905e926ad298332963e1bbaf010046
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAP2 BASP1 SCG2 ZFHX2 TMEM35A ALK	5.88e-05	194	154	6	5bd0f739aa75f387cca7c3b2686493ee2d1ee968
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	MAP1A MAP2 TCEAL5 GPR158 SCG2 PDZD4	5.88e-05	194	154	6	1e1f4139ad584f493d75a9b7f1568eca4653c5a2
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F8 EMILIN1 STOX2 FCGR2B USHBP1 PPP1R16B	6.05e-05	195	154	6	f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F8 EMILIN1 STOX2 FCGR2B USHBP1 PPP1R16B	6.05e-05	195	154	6	ea1b00805391dca8be0883b635768b296369919a
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 F8 EMILIN1 FCGR2B USHBP1 PPP1R16B	6.05e-05	195	154	6	12ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F8 EMILIN1 STOX2 FCGR2B USHBP1 PPP1R16B	6.05e-05	195	154	6	85df110f753f58ab017018c54ee454edb4428e29
ToppCell	COVID-19-Heart-EC_1\|Heart / Disease (COVID-19 only), tissue and cell type	CDK17 MAP2 F8 STOX2 PPP1R16B AFDN	6.05e-05	195	154	6	50a193475db1bb1e05b8590225a553688c372c14
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-6_mon-Neuronal-INs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	YBX1 CRACD BASP1 PAFAH1B3 AFDN KAT6B	6.23e-05	196	154	6	556e18eae05bf19259fe02848bcc9120aa2a9d29
ToppCell	BAL-Mild-cDC_10\|Mild / Compartment, Disease Groups and Clusters	FNBP1 DCAF6 ZEB1 NUAK2 CRACD BASP1	6.40e-05	197	154	6	c0550d41dd5619b369b590f3d6a61154dd7b2cab
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 F8 EMILIN1 STOX2 FCGR2B USHBP1	6.59e-05	198	154	6	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Neuron\|1m / Sample Type, Dataset, Time_group, and Cell type.	MAP1A MAP2 AMER2 BASP1 SCG2 DNAJC12	6.96e-05	200	154	6	be1e153119ca4946b4eaef6037e8465f5c00ca6f
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal\|3m / Sample Type, Dataset, Time_group, and Cell type.	MAP2 AMER2 BASP1 PAFAH1B3 AFDN TMEM35A	6.96e-05	200	154	6	af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal\|1m / Sample Type, Dataset, Time_group, and Cell type.	MAP2 BASP1 SCG2 PAFAH1B3 DNAJC12 TMEM35A	6.96e-05	200	154	6	418821561c8949ed96c07f9bea3aabc287c04ff1
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	OAS3 ZCCHC2 SETD2 ANKRD11 KMT2A TOP1	6.96e-05	200	154	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Interneuron\|5w / Sample Type, Dataset, Time_group, and Cell type.	MAP2 APC BASP1 PAFAH1B3 PPP1R16B TMEM35A	6.96e-05	200	154	6	c7e33057466915d4e2b34f2062b22d9cdffa69dc
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	MAP2 BASP1 SCG2 TMEM35A KAT6B PRRC2B	6.96e-05	200	154	6	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PAPPA2 FNDC4 NLGN4X ZFHX2 GJA10	8.30e-05	128	154	5	003e133469899a9abe3a7f6d7f580583b281f412
ToppCell	Fetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CACNA1A MEIOC SCG2 ZFHX2 ALK	1.35e-04	142	154	5	819e983688d126d89a71abc03d72525cc759a347
ToppCell	droplet-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAS3 NCF2 NUAK2 FCGR2B IL17RA	1.40e-04	143	154	5	4d11d53330a9197275a8851e1bbf55a113715a09
ToppCell	droplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OAS3 NCF2 NUAK2 FCGR2B IL17RA	1.40e-04	143	154	5	8b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Gkn1_Pcdh19\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ABCC4 CAPN3 IGFBP6 PALM3 IL17RA	1.44e-04	144	154	5	e8caeb6485f4c8f9a3384570dc69024c2bcc9ab0
ToppCell	TCGA-Blood_and_Bone_Marrow-Primary_Blood_Derived_Cancer_-_Peripheral_Blood-Leukemia-Acute_Myeloid_Leukemia-7\|TCGA-Blood_and_Bone_Marrow / Sample_Type by Project: Shred V9	CRACD SMTNL1 TET1 KMT2A BTRC	1.49e-04	145	154	5	88090a226ddfa6df59976f025bf0fd84ca0f72ef
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NLGN4Y MDM1 TDRD1 NFATC2 PPP1R16B	1.69e-04	149	154	5	1328ce0104d40215ee68abfdbf74eb47b87a7b5b
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	FAM234A SELENOS MAP1A ZCCHC2 TDRD1	1.86e-04	152	154	5	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NAP1L5 LHX6 PPARGC1A NLGN4X UNC13C	1.86e-04	152	154	5	655d47efe0608d729801f1f01668e84c1bc0675f
ToppCell	facs-Heart-RV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 NCF2 FCGR2B BASP1 C17orf78	1.92e-04	153	154	5	af0ae08ff35f8210268457e5e15bcbe5d1f46d67
ToppCell	facs-Heart-RV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2 NCF2 FCGR2B BASP1 C17orf78	1.92e-04	153	154	5	984a2d847f4376183fdbab7ebc77c1bf7d448f44
ToppCell	remission-unassigned\|remission / disease stage, cell group and cell class	TACC2 YARS1 IGSF22 TXLNB IGFBP6	1.97e-04	154	154	5	4130769829b838cc8a075c87ff6c187f0f507f8b
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAP1A SAMD15 DNAJC12 KIAA2012 CFAP46	1.97e-04	154	154	5	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; PC3; HT_HG-U133A	CDK17 NRIP1 ZEB1 DAB2 APC TACC2 JMJD1C ZBED5 SETD2 RCOR1 KAT6B	3.42e-08	180	151	11	4541_DN
Drug	Oxyphenbutazone [129-20-4]; Down 200; 12.4uM; MCF7; HT_HG-U133A	CDK17 ZEB1 KIAA0319L NLGN1 TDRD1 ZNF750 SALL2 IGFBP6 SCG2 YLPM1 BTRC	8.61e-08	197	151	11	3582_DN
Drug	Moxalactam disodium salt [64953-12-4]; Up 200; 7uM; MCF7; HT_HG-U133A	PAPPA2 PRUNE2 CRYBG2 ZEB1 MAP1A CAST DAB2 POLL SLC24A1	6.13e-06	194	151	9	5609_UP
Disease	myeloid white cell count	PRUNE2 FKBP15 NRIP1 RC3H1 RCSD1 ZCCHC2 JMJD1C SAMD15 SETD2 FCGR2B DNAJC12 AKAP11 IL17RA ATP2A2	1.93e-04	937	143	14	EFO_0007988
Disease	Endometrioid carcinoma ovary	NUAK2 FER	2.31e-04	5	143	2	C0346163
Disease	age related macular degeneration (implicated_via_orthology)	MDM1 PPARGC1A	3.45e-04	6	143	2	DOID:10871 (implicated_via_orthology)
Disease	leiomyoma (is_implicated_in)	XRCC1 KAT6B	3.45e-04	6	143	2	DOID:127 (is_implicated_in)
Disease	asphyxia neonatorum (biomarker_via_orthology)	MAP2 XRCC1	3.45e-04	6	143	2	DOID:11088 (biomarker_via_orthology)
Disease	malignant mesothelioma (is_implicated_in)	XRCC1 SETD2	4.82e-04	7	143	2	DOID:1790 (is_implicated_in)
Disease	serum gamma-glutamyl transferase measurement	ZEB1 MAP1A COBLL1 JMJD1C SETD2 RCOR1 FCGR2B PTCD1 PALM3 KMT2A DNMBP HSPA4 TOP1	5.23e-04	914	143	13	EFO_0004532
Disease	gut microbiome measurement, bone density	ZEB1 PPARGC1A FCGR2B NFATC2	5.71e-04	78	143	4	EFO_0003923, EFO_0007874
Disease	citrate measurement	CAPN3 JMJD1C NLGN4X ALK	5.99e-04	79	143	4	EFO_0010114
Disease	breast cancer anti-estrogen resistance protein 3 measurement	VTN JMJD1C	6.41e-04	8	143	2	EFO_0008040
Disease	calpastatin measurement	VTN DNMBP	6.41e-04	8	143	2	EFO_0008065
Disease	liver cancer (is_marker_for)	XRCC1 SETD2	8.21e-04	9	143	2	DOID:3571 (is_marker_for)
Disease	Prostatic Neoplasms	ABCC4 DCAF6 SELENOS APC XRCC1 GHR SETD2 IGFBP6 KMT2A SPEN	8.73e-04	616	143	10	C0033578
Disease	Malignant neoplasm of prostate	ABCC4 DCAF6 SELENOS APC XRCC1 GHR SETD2 IGFBP6 KMT2A SPEN	8.73e-04	616	143	10	C0376358
Disease	autism spectrum disorder (implicated_via_orthology)	ZNF280D NLGN4Y NLGN1 NLGN4X NLGN2	8.91e-04	152	143	5	DOID:0060041 (implicated_via_orthology)
Disease	apolipoprotein A 1 measurement	PAPPA2 VTN MAP1A NEIL2 IQCF1 COBLL1 JMJD1C RCOR1 FCGR2B YLPM1 FER KMT2A	8.98e-04	848	143	12	EFO_0004614
Disease	Anorectal Malformations	FNBP1 RCSD1 NLGN1	1.04e-03	41	143	3	C3495676
Disease	neutrophil count	PAPPA2 CACNA1A PRUNE2 NEIL2 RC3H1 RCSD1 ZCCHC2 JMJD1C SAMD15 SETD2 FCGR2B ANKRD11 DNAJC12 AKAP11 UNC13C IL17RA	1.11e-03	1382	143	16	EFO_0004833
Disease	gastrin-releasing peptide measurement	VTN JMJD1C	1.25e-03	11	143	2	EFO_0022000
Disease	argininosuccinate measurement	ABCC4 ALK	1.25e-03	11	143	2	EFO_0010461
Disease	3-hydroxyanthranilate 3,4-dioxygenase measurement	VTN DNMBP	1.25e-03	11	143	2	EFO_0021862
Disease	chronic kidney disease, Proteinuria	CACNA1A KMT2A	1.25e-03	11	143	2	EFO_0003884, HP_0000093
Disease	Schizophrenia	NRIP1 APC NLGN1 XRCC1 LHX6 PPARGC1A SYNGR1 TET1 KMT2A NLGN2 ATP2A2 ALK	1.27e-03	883	143	12	C0036341
Disease	triglyceride measurement, alcohol drinking	NEIL2 COBLL1 CAPN3 HSPA4	1.39e-03	99	143	4	EFO_0004329, EFO_0004530
Disease	Alzheimer disease, dementia	LHX6 CFAP46	1.49e-03	12	143	2	MONDO_0001627, MONDO_0004975
Disease	triglyceride measurement, alcohol consumption measurement	NEIL2 COBLL1 CAPN3 HSPA4	1.50e-03	101	143	4	EFO_0004530, EFO_0007878
Disease	gallbladder cancer (is_implicated_in)	APC XRCC1	1.76e-03	13	143	2	DOID:3121 (is_implicated_in)
Disease	fibrinogen measurement	CAPN3 JMJD1C NLGN4X RAB5C	1.98e-03	109	143	4	EFO_0004623
Disease	congenital hypothyroidism (biomarker_via_orthology)	GHR PPARGC1A	2.04e-03	14	143	2	DOID:0050328 (biomarker_via_orthology)
Disease	obsolete_red blood cell distribution width	NRIP1 XRN2 FAM234A ZNF280D MYO19 RC3H1 ZCCHC2 F8 REXO1 RCOR1 GPR158 YLPM1 AFDN BTRC TRAPPC9	2.32e-03	1347	143	15	EFO_0005192
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	JMJD1C SCG2	2.68e-03	16	143	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	neutrophil collagenase measurement	VTN DNMBP	2.68e-03	16	143	2	EFO_0008248
Disease	Alzheimer's disease (implicated_via_orthology)	MAP2 PPARGC1A RCOR1	2.69e-03	57	143	3	DOID:10652 (implicated_via_orthology)
Disease	colorectal cancer (is_implicated_in)	AMER1 APC XRCC1 SETD2	2.90e-03	121	143	4	DOID:9256 (is_implicated_in)
Disease	Precursor Cell Lymphoblastic Leukemia Lymphoma	XRCC1 SETD2 KMT2A	3.27e-03	61	143	3	C1961102
Disease	urate measurement, bone density	FNBP1 RC3H1 FSIP2 PPARGC1A SALL2 ANKRD11 PPP1R16B KAT6B PRRC2B	3.30e-03	619	143	9	EFO_0003923, EFO_0004531
Disease	testosterone measurement	AMER1 ZNF280D MAP1A COBLL1 CAST C16orf96 JMJD1C REXO1 MCM9 PALM3 NLGN2 SLC24A1 DNMBP CHP1	3.68e-03	1275	143	14	EFO_0004908
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	MAP2 C2orf88 JMJD1C KAT6B	3.85e-03	131	143	4	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	MAP2 C2orf88 JMJD1C KAT6B	3.85e-03	131	143	4	C4552091
Disease	Juvenile arthritis	MAP2 C2orf88 JMJD1C KAT6B	3.85e-03	131	143	4	C3495559
Disease	Juvenile psoriatic arthritis	MAP2 C2orf88 JMJD1C KAT6B	3.85e-03	131	143	4	C3714758
Disease	Parkinson's disease (is_marker_for)	CAST PPARGC1A AFDN	4.26e-03	67	143	3	DOID:14330 (is_marker_for)
Disease	Juvenile-Onset Still Disease	MAP2 C2orf88 JMJD1C KAT6B	4.29e-03	135	143	4	C0087031

Protein segments in the cluster

Peptide	Gene	Start	Entry
SAESNSPPKEVNIKP	TDRD1	116	Q9BXT4
QQNPQPSPEGSSVDK	USHBP1	401	Q8N6Y0
SEVNNVNPKKPKPSE	ZNF280D	181	Q6N043
ENDAIPPKKAQSNGP	AFDN	131	P55196
NKNANPDPLPKKEEE	CACNA1A	1186	O00555
GNPSKNEDNVKSAPP	FAM234A	26	Q9H0X4
PKHPEKEQQEGVPNS	AMER2	506	Q8N7J2
NQSKQGPPPSEKECA	ANKRD11	2346	Q6UB99
SDNEEGPPPKNKVLS	BCORP1	26	Q8N888
PQPRQLEVDPSNGKK	GJA10	306	Q969M2
NNGEPPRKIIPEKNS	BTRC	61	Q9Y297
KPANPTNPDEADKVG	FCGR2B	271	P31994
EQQLTKESTPGPKEP	RTL10	256	Q7L3V2
EEKVKEPKQSQSPAP	CFAP46	1396	Q8IYW2
PKVDLGQNGEEKSPP	RCSD1	56	Q6JBY9
ESKPDSQPQKVGQDA	C17orf78	241	Q8N4C9
EPKPLEKSVSPQNSD	DNAJC12	151	Q9UKB3
KENANPQDAPGPKVS	AMER1	226	Q5JTC6
TPEKSPKFPDSQNQL	AKAP11	981	Q9UKA4
ENFPETKPQKDDPGT	AGGF1	691	Q8N302
KQPQDASPPPKECDQ	DNMBP	1401	Q6XZF7
NNNEKLSPKPGTGEP	DCAF6	461	Q58WW2
QSGAPKPEENPSLNI	AP3M1	361	Q9Y2T2
ETEFKQNVGPPPKDL	C5orf64	41	Q2M2E5
APNPAPKELTNKEAE	COBLL1	891	Q53SF7
VANVQSFPPAPEDKK	ARRB1	81	P49407
VSPPQKAKEAPNTQA	POLL	176	Q9UGP5
GQPEPQNKVPAEDLT	RC3H1	1066	Q5TC82
GPSNQKPVKSPDNSI	RCOR1	451	Q9UKL0
GEPQKGQPEPAKDQQ	RBM28	606	Q9NW13
KLPKNEPQNATGAPG	RAB5C	181	P51148
PQKTKEPSKEDEPQQ	IQCF1	6	Q8N6M8
TETRPEKEGPQPQEK	PALM3	566	A6NDB9
NPASKPTPVQDVQGD	PAFAH1B3	6	Q15102
ESDEEPPPGEQAQKQ	KAT6B	1501	Q8WYB5
PPPGEQAQKQDQKNS	KAT6B	1506	Q8WYB5
QVQKANSPEKPPEAG	LRWD1	206	Q9UFC0
NGQPDQQAAPKAPSK	DAB2	11	P98082
KNGPPVSDQKEVLPA	NFATC2	876	Q13469
KPIPDGDPNHQSKNF	IL17RA	166	Q96F46
KELSSEPQTPPAQKG	MAP1A	496	P78559
EPPKEEQKNAEQNGP	HSPA4	791	P34932
PEPPQKEVQKEGAAD	NEIL2	71	Q969S2
PGRPQLSPGQKQKEE	NCF2	326	P19878
TPAPVPDIKGDQKEN	SLC24A1	726	O60721
DGQQQPQPEKPESTL	GPANK1	21	O95872
EVPQKVGSEQKEPPE	INCENP	366	Q9NQS7
AGSPPETNEKLTNPQ	KAAG1	66	Q9UBP8
KPKPDPAQQTDSQNS	MTMR10	611	Q9NXD2
KEKTQEEPPGQSRAP	MYO19	576	Q96H55
SNPAEEPRKPQKSGI	GPR158	961	Q5T848
NKPPQADAGPDKELT	KIAA0319L	596	Q8IZA0
PESQQQNTPPKSEKN	JMJD1C	1971	Q15652
AKAEPPKAPEQEQAA	BASP1	96	P80723
IKSEPSKPDDPQNQR	FSIP2	5761	Q5CZC0
SKPDDPQNQRESKPG	FSIP2	5766	Q5CZC0
PAPQNKDQKAVDPED	EBNA1BP2	86	Q99848
KLKSPPAQQPGNEEE	PDZD4	246	Q76G19
GEPQPPQLKKDDVTS	FKBP15	1116	Q5T1M5
PEAPETPKSQEAEQK	MDM1	86	Q8TC05
PEDYVPVSKPQDKNN	KIAA2012	36	Q0VF49
KDPPGEKPAQNEGAQ	NRIP1	606	P48552
GAVPSEQDSQPKPAK	LHX6	206	Q9UPM6
VQQKKEGPIPPDAQN	F8	1096	P00451
SKDNEPIVKNGRPPT	CDK17	36	Q00537
FAKTGDPNQPVPQDT	NLGN1	586	Q8N2Q7
PPNQEDKPGARTLKS	CRACDL	841	Q6NV74
SPNDPKGSPFENKTI	PPARGC1A	266	Q9UBK2
LKKDNEESEQPPVPG	ABCC4	631	O15439
TDQENKDPNPRLEKP	PPP1R16B	391	Q96T49
AKTGDPNQPVPQDTK	NLGN4Y	531	Q8NFZ3
VKKSPPEESNQNGGE	PAPPA2	231	Q9BXP8
GSDPNPNKENSEETK	FRG2C	61	A6NGY1
TDPVPDPRAVNQDKK	ATP2A2	191	P16615
NEKEKPQANVPSALP	CFDP1	196	Q9UEE9
EKPQPVTAPEGDKAV	IGSF22	71	Q8N9C0
APSKPEPQGKAQQSQ	LINC01599	26	Q8WXQ3
DGAPKEAQPKAPQSA	C16orf96	546	A6NNT2
AEKNKPQPLPTEGAE	GHR	451	P10912
SAVPNGPQSPKQQKE	FNBP1	351	Q96RU3
QKVQENDGKEPPPVV	FER	386	P16591
KKQAPVENISPEAPA	C19orf44	176	Q9H6X5
NNPKEKGKGPEQSPQ	FNDC4	201	Q9H6D8
PATQQEKPSQTPEAG	CRACD	1046	Q6ZU35
GEDDNKSPFPLQPKN	INTS14	381	Q96SY0
PKQDKGVQDSEGSPI	CRYBG2	676	Q8N1P7
QPPTAKDGPEEQAKF	HOXD12	86	P35452
LLDDNGQDKPVKPPT	CAST	621	P20810
EKEKPPPVNKQENAG	KMT2A	1361	Q03164
EGLENKPVAESQPSP	EMILIN1	951	Q9Y6C2
DKQKQSPQPQPGSSD	CAPN3	631	P20807
KSNEKKNPQPPEETG	SAMD15	366	Q9P1V8
AVEPKNKADENTPPG	SALL2	516	Q9Y467
FAKTGDPNQPVPQDT	NLGN2	541	Q8NFZ4
AKTGDPNQPVPQDTK	NLGN4X	531	Q8N0W4
QKADAPAVSPESPQK	C3orf86	31	P0DN24
NPKESKPQAGTARPQ	IGFBP6	116	P24592
SEAKPAQPQPTGEKE	DELE1	206	Q14154
QESQESESEGKQPPP	PTCHD3	31	Q3KNS1
PIQLDPNQKTPENSK	OAS3	356	Q9Y6K5
PQGETKEVSQQPPEK	MCM9	986	Q9NXL9
QAKAPPPKQDFTQGA	PYGO1	231	Q9Y3Y4
ANVTEKQQFAKPDPP	MEIOC	436	A2RUB1
ADPEIKATGQPPSKE	REXO1	311	Q8N1G1
VENEAKGNFPPQKKP	UTP18	126	Q9Y5J1
AKGPAKNSEPEEVIP	YARS1	351	P54577
KQPDPESAPSQKLTG	TGIF2LX	171	Q8IUE1
KGPSFAEAKENPLPQ	TDRD3	416	Q9H7E2
TNSKPPKEDQNGLVD	PRUNE2	891	Q8WUY3
EEAPAQAKPSGKAPQ	TCOF1	421	Q13428
QTPAENAPKPKNDFI	NAP1L5	56	Q96NT1
QFENTGPPPADKEKI	RNF126	196	Q9BV68
AENEPQSAPKENKPY	SCG2	121	P13521
QGQTTDPSERKKPAP	SIN3B	721	O75182
DVFVSGDPKEQKPPQ	NUAK2	476	Q9H093
TRKQGDLQPPAKPEQ	TBC1D3L	351	B9A6J9
KEATPQPKFEAPDGQ	NPAP1	641	Q9NZP6
QPKFEAPDGQPQKAS	NPAP1	646	Q9NZP6
NEGDQPKTPENIPSK	TET1	851	Q8NFU7
NKELKPGENSPRQTP	ALK	661	Q9UM73
TPDQEEKPFTSNKGP	APC	2151	P25054
PDQKGTEIKPGQNNP	APC	2731	P25054
NEKSKDVNGPEPLNS	CHP1	96	Q99653
QKSEVVVPAPKPADG	ZCCHC2	731	Q9C0B9
NAKKPQEEDSPGPST	SELENOS	131	Q9BQE4
PKSNSLDPKQTNQPD	ZNF750	66	Q32MQ0
LDPKQTNQPDATAKP	ZNF750	71	Q32MQ0
PVKEGQPSPADEKGN	VPS4B	86	O75351
RPENPKPQDGKETKA	YBX1	291	P67809
LAEPPTPEKDAQNKT	ZFHX2	941	Q9C0A1
PSKKQDIPREDQGPT	UNC13C	1571	Q8NB66
KDAGTDKNPPETAPV	SPEN	2046	Q96T58
QHPEAPQEEKQSEKP	SPEN	2376	Q96T58
AINEGPPTESGKQEK	SMTNL1	41	A8MU46
SAEPPTNEAEKLQKP	STOX2	901	Q9P2F5
GVKIPVDASKPNPND	XRN2	31	Q9H0D6
SEGKPASQAKPESQP	TCEAL5	86	Q5H9L2
EQAPKPSEQKDSEQG	PRRC2B	1716	Q5JSZ5
QVSKPKDNPLNEGTD	SYNGR1	131	O43759
KEQAQPPENGKETSP	TACC2	846	O95359
PGKQQAPEKPGEATL	TACC2	1141	O95359
NNDKAPESESEKPTP	ZNF518A	381	Q6AHZ1
PVNVKEEVKEPPGTN	C2orf88	41	Q9BSF0
EGKPASQAKPESQPR	TCEAL3	81	Q969E4
ALGNEKQSDTPNPPA	SETD2	91	Q9BYW2
QPKSQAEPLSGNKEP	YLPM1	851	P49750
QTGKESQPSPPAQEA	MAP2	621	P11137
DPSKQPKNQLNPIGS	PRKRA	116	O75569
SPEPGKVNIPAKNND	ZEB1	646	P37275
ENNKPPTPKIVNTDN	ZBED5	176	Q49AG3
KLEPEGEAQPQAQPE	TSSK1B	311	Q9BXA7
SGDEAPKLPQKQPQT	XRCC1	421	P18887
PESPGEKGQFANPKQ	TRAPPC9	951	Q96Q05
KQQDSPKERSPQSPG	ZNF576	11	Q9H609
SGEPPTVKEPVSNKE	TXLNB	116	Q8N3L3
PQAPSGKDAEKTPAV	SLC30A1	451	Q9Y6M5
VPGKAQPEVDTKAEP	PTCD1	406	O75127
SPGKQKEIQEPDPTY	SMARCA5	66	O60264
SKGNPEQTPVLKPEE	VTN	106	P04004
KENGFSSPPQIKDEP	TOP1	106	P11387
QVPAQTPASPAKDKV	USP44	231	Q9H0E7
DAPCPQETKSKQVPG	ZAR1L	191	A6NP61
EKKPLPGNAEEQPSL	TMEM35A	141	Q53FP2