Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase activator activity	TBC1D3E TBC1D3 SRGAP2 TBC1D3C IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20 TBC1D3K TBC1D3F	3.99e-09	279	89	12	GO:0005096
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	TBC1D3E TBC1D3 SRGAP2 TBC1D3C DENND2B IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 DGKI ARHGAP20 TBC1D3K TBC1D3F	5.17e-08	507	89	14	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	TBC1D3E TBC1D3 SRGAP2 TBC1D3C DENND2B IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 DGKI ARHGAP20 TBC1D3K TBC1D3F	5.17e-08	507	89	14	GO:0030695
GeneOntologyMolecularFunction	enzyme activator activity	TBC1D3E TBC1D3 SRGAP2 TBC1D3C IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 BRPF1 ARHGAP20 TBC1D3K TBC1D3F	6.54e-06	656	89	13	GO:0008047
GeneOntologyMolecularFunction	enzyme regulator activity	TBC1D3E ERCC4 TBC1D3 WASHC1 SRGAP2 TBC1D3C DENND2B IQGAP1 WASH3P DLC1 SRGAP3 SYDE2 SRGAP1 BRPF1 DGKI ARHGAP20 TBC1D3K TBC1D3F	4.52e-05	1418	89	18	GO:0030234
GeneOntologyMolecularFunction	G protein-coupled serotonin receptor activity	HTR1A HTR1B CHRM3	1.24e-04	22	89	3	GO:0004993
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase inhibitor activity	WASHC1 WASH3P	5.41e-04	8	89	2	GO:0141039
GeneOntologyMolecularFunction	G protein-coupled amine receptor activity	HTR1A HTR1B CHRM3	8.07e-04	41	89	3	GO:0008227
GeneOntologyMolecularFunction	neurotransmitter receptor activity	DRD2 HTR1A HTR1B CHRM3	1.04e-03	100	89	4	GO:0030594
GeneOntologyMolecularFunction	molecular function activator activity	CACNA1S TBC1D3E TBC1D3 SRGAP2 TBC1D3C IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 BRPF1 ARHGAP20 TBC1D3K TBC1D3F	1.07e-03	1233	89	14	GO:0140677
GeneOntologyMolecularFunction	GTPase inhibitor activity	IQGAP1 DGKI	1.48e-03	13	89	2	GO:0005095
GeneOntologyMolecularFunction	serotonin binding	HTR1A HTR1B	1.48e-03	13	89	2	GO:0051378
GeneOntologyBiologicalProcess	activation of GTPase activity	TBC1D3E TBC1D3 TBC1D3C SYDE2 TBC1D3K TBC1D3F	7.72e-06	109	89	6	GO:0090630
GeneOntologyBiologicalProcess	presynaptic modulation of chemical synaptic transmission	DRD2 HTR1A HTR1B APBA1 DGKI	1.04e-05	67	89	5	GO:0099171
GeneOntologyBiologicalProcess	regulation of GTPase activity	TBC1D3E TBC1D3 SRGAP2 TBC1D3C IQGAP1 SYDE2 DGKI TBC1D3K TBC1D3F	1.43e-05	335	89	9	GO:0043087
GeneOntologyBiologicalProcess	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	SRGAP2 SRGAP2C	1.84e-05	2	89	2	GO:0021816
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	DRD2 HTR1A HTR1B SSTR2 CHRM3	3.53e-05	86	89	5	GO:0007193
GeneOntologyBiologicalProcess	pseudopodium assembly	WASHC1 SRGAP2 SRGAP2C	5.05e-05	17	89	3	GO:0031269
GeneOntologyBiologicalProcess	pseudopodium organization	WASHC1 SRGAP2 SRGAP2C	7.16e-05	19	89	3	GO:0031268
GeneOntologyBiologicalProcess	gamma-aminobutyric acid secretion	HTR1A HTR1B APBA1	8.39e-05	20	89	3	GO:0014051
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	TBC1D3E TBC1D3 SRGAP2 TBC1D3C SYDE2 TBC1D3K TBC1D3F	8.99e-05	244	89	7	GO:0043547
GeneOntologyBiologicalProcess	acid secretion	DRD2 HTR1A HTR1B APBA1	1.07e-04	57	89	4	GO:0046717
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly actin filament organization	IQGAP1 PLEC	1.10e-04	4	89	2	GO:2000689
GeneOntologyBiologicalProcess	G protein-coupled serotonin receptor signaling pathway	HTR1A HTR1B CHRM3	1.29e-04	23	89	3	GO:0098664
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	HTR1A HTR1B SSTR2 CHRM3	1.40e-04	61	89	4	GO:0007187
GeneOntologyBiologicalProcess	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration	SRGAP2 SRGAP2C	1.83e-04	5	89	2	GO:0021815
GeneOntologyBiologicalProcess	gamma-aminobutyric acid transport	HTR1A HTR1B APBA1	2.35e-04	28	89	3	GO:0015812
GeneOntologyBiologicalProcess	cytokinesis	DRD2 WASHC1 PRPF40A IQGAP1 WASH3P PLEC	2.56e-04	204	89	6	GO:0000910
GeneOntologyBiologicalProcess	telencephalon cell migration	DRD2 SRGAP2 SRGAP2C ARL13B	2.66e-04	72	89	4	GO:0022029
GeneOntologyBiologicalProcess	positive regulation of cholesterol import	WASHC1 WASH3P	2.73e-04	6	89	2	GO:1904109
GeneOntologyBiologicalProcess	negative regulation of gamma-aminobutyric acid secretion	HTR1A HTR1B	2.73e-04	6	89	2	GO:0014053
GeneOntologyBiologicalProcess	forebrain cell migration	DRD2 SRGAP2 SRGAP2C ARL13B	3.12e-04	75	89	4	GO:0021885
GeneOntologyBiologicalProcess	desensitization of G protein-coupled receptor signaling pathway	DRD2 HTR1B GRK5	3.20e-04	31	89	3	GO:0002029
GeneOntologyBiologicalProcess	negative adaptation of signaling pathway	DRD2 HTR1B GRK5	3.52e-04	32	89	3	GO:0022401
GeneOntologyBiologicalProcess	adaptation of signaling pathway	DRD2 HTR1B GRK5	3.52e-04	32	89	3	GO:0023058
GeneOntologyBiologicalProcess	cell motility involved in cerebral cortex radial glia guided migration	SRGAP2 SRGAP2C	3.81e-04	7	89	2	GO:0021814
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting serotonin receptor signaling pathway	HTR1A HTR1B	3.81e-04	7	89	2	GO:0007198
GeneOntologyBiologicalProcess	positive regulation of catalytic activity	TBC1D3E TBC1D3 TCIM SRGAP2 TBC1D3C IQGAP1 DLC1 SYDE2 UHRF1 CLSPN TOPORS TBC1D3K TBC1D3F	4.51e-04	1028	89	13	GO:0043085
GeneOntologyBiologicalProcess	interneuron migration from the subpallium to the cortex	DRD2 ARL13B	6.50e-04	9	89	2	GO:0021830
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly	IQGAP1 PLEC	6.50e-04	9	89	2	GO:0000915
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in cytokinesis	IQGAP1 PLEC	6.50e-04	9	89	2	GO:0000912
GeneOntologyBiologicalProcess	regulation of cholesterol import	WASHC1 WASH3P	6.50e-04	9	89	2	GO:0060620
GeneOntologyBiologicalProcess	polar body extrusion after meiotic divisions	WASHC1 WASH3P	8.10e-04	10	89	2	GO:0040038
GeneOntologyBiologicalProcess	actomyosin contractile ring organization	IQGAP1 PLEC	8.10e-04	10	89	2	GO:0044837
GeneOntologyBiologicalProcess	negative regulation of amine transport	DRD2 HTR1A HTR1B	8.46e-04	43	89	3	GO:0051953
Domain	NPIP	NPIPB15 NPIPB9 NPIPA1 NPIPB3 NPIPB5 NPIPA7 NPIPB13 NPIPA5	1.15e-15	14	97	8	IPR009443
Domain	FCH	SRGAP2 SRGAP2C SRGAP3 SRGAP1 SRGAP2B	8.36e-08	22	97	5	PF00611
Domain	FCH	SRGAP2 SRGAP2C SRGAP3 SRGAP1 SRGAP2B	8.36e-08	22	97	5	SM00055
Domain	FCH_dom	SRGAP2 SRGAP2C SRGAP3 SRGAP1 SRGAP2B	1.06e-07	23	97	5	IPR001060
Domain	srGAP2	SRGAP2 SRGAP2C SRGAP2B	1.36e-07	3	97	3	IPR030252
Domain	F_BAR	SRGAP2 SRGAP2C SRGAP3 SRGAP1 SRGAP2B	1.67e-07	25	97	5	IPR031160
Domain	F_BAR	SRGAP2 SRGAP2C SRGAP3 SRGAP1 SRGAP2B	1.67e-07	25	97	5	PS51741
Domain	Rho_GTPase_activation_prot	SRGAP2 IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	3.69e-07	88	97	7	IPR008936
Domain	RhoGAP	SRGAP2 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	8.16e-07	62	97	6	SM00324
Domain	RhoGAP	SRGAP2 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	8.98e-07	63	97	6	PF00620
Domain	RHOGAP	SRGAP2 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	9.87e-07	64	97	6	PS50238
Domain	RhoGAP_dom	SRGAP2 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	9.87e-07	64	97	6	IPR000198
Domain	-	SRGAP2 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	9.87e-07	64	97	6	1.10.555.10
Domain	7TM_GPCR_Srsx	DRD2 HTR1A HTR1B SSTR2 CHRM3 GPR83	2.58e-05	112	97	6	SM01381
Domain	TBC	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	1.21e-04	49	97	4	SM00164
Domain	RabGAP-TBC	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	1.65e-04	53	97	4	PF00566
Domain	TBC_RABGAP	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	1.90e-04	55	97	4	PS50086
Domain	Rab-GTPase-TBC_dom	TBC1D3E TBC1D3C TBC1D3K TBC1D3F	1.90e-04	55	97	4	IPR000195
Domain	5HT_rcpt	HTR1A HTR1B	9.39e-04	9	97	2	IPR002231
Domain	AGC-kinase_C	RPS6KA5 GRK5 MAST4	3.08e-03	56	97	3	IPR000961
Domain	AGC_KINASE_CTER	RPS6KA5 GRK5 MAST4	3.08e-03	56	97	3	PS51285
Domain	S_TK_X	RPS6KA5 GRK5 MAST4	3.08e-03	56	97	3	SM00133
Domain	Cyclophilin-type_PPIase_CS	CWC27 NKTR	4.31e-03	19	97	2	IPR020892
Domain	UBA-like	DHX57 CUEDC1 TNRC6A	4.50e-03	64	97	3	IPR009060
Domain	Cyclophilin-type_PPIase	CWC27 NKTR	5.26e-03	21	97	2	IPR024936
Domain	SH3	AHI1 SRGAP2 SRGAP3 SRGAP1 MYO15A	5.38e-03	216	97	5	SM00326
Domain	SH3	AHI1 SRGAP2 SRGAP3 SRGAP1 MYO15A	5.38e-03	216	97	5	PS50002
Domain	Cyclophilin-like_dom	CWC27 NKTR	5.76e-03	22	97	2	IPR029000
Domain	CSA_PPIASE_2	CWC27 NKTR	5.76e-03	22	97	2	PS50072
Domain	Pro_isomerase	CWC27 NKTR	5.76e-03	22	97	2	PF00160
Domain	-	CWC27 NKTR	5.76e-03	22	97	2	2.40.100.10
Domain	Cyclophilin-type_PPIase_dom	CWC27 NKTR	5.76e-03	22	97	2	IPR002130
Domain	CSA_PPIASE_1	CWC27 NKTR	5.76e-03	22	97	2	PS00170
Domain	SH3_domain	AHI1 SRGAP2 SRGAP3 SRGAP1 MYO15A	5.81e-03	220	97	5	IPR001452
Pathway	WP_17Q12_COPY_NUMBER_VARIATION_SYNDROME	TBC1D3E TBC1D3 DDX52 TBC1D3C NEUROD2 TBC1D3K	3.79e-06	99	60	6	M46448
Pathway	REACTOME_INACTIVATION_OF_CDC42_AND_RAC1	SRGAP2 SRGAP3 SRGAP1	4.04e-06	8	60	3	M27349
Pathway	WP_MONOAMINE_GPCRS	DRD2 HTR1A HTR1B CHRM3	8.56e-06	31	60	4	MM15871
Pathway	REACTOME_RAC1_GTPASE_CYCLE	SRGAP2 IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	8.94e-06	175	60	7	MM15599
Pathway	WP_MONOAMINE_GPCRS	DRD2 HTR1A HTR1B CHRM3	1.11e-05	33	60	4	M39585
Pathway	REACTOME_RAC1_GTPASE_CYCLE	SRGAP2 IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 ARHGAP20	1.24e-05	184	60	7	M41809
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	DRD2 HTR1A HTR1B CHRM3	2.94e-05	42	60	4	M5868
Pathway	REACTOME_AMINE_LIGAND_BINDING_RECEPTORS	DRD2 HTR1A HTR1B CHRM3	2.94e-05	42	60	4	MM14971
Pathway	REACTOME_CDC42_GTPASE_CYCLE	SRGAP2 DLC1 SRGAP3 SRGAP1 ARHGAP20	4.84e-05	94	60	5	MM15598
Pathway	REACTOME_CDC42_GTPASE_CYCLE	SRGAP2 IQGAP1 DLC1 SRGAP3 SRGAP1 ARHGAP20	4.92e-05	155	60	6	M41808
Pathway	REACTOME_RHOQ_GTPASE_CYCLE	SRGAP2 IQGAP1 DLC1 ARL13B	1.06e-04	58	60	4	MM15602
Pathway	REACTOME_RHOQ_GTPASE_CYCLE	SRGAP2 IQGAP1 DLC1 ARL13B	1.13e-04	59	60	4	M41812
Pathway	REACTOME_RHO_GTPASE_CYCLE	SRGAP2 IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 ARL13B ARHGAP20	5.13e-04	439	60	8	MM15595
Pathway	WP_SEROTONIN_HTR1_GROUP_AND_FOS_PATHWAY	HTR1A HTR1B RPS6KA5	5.14e-04	37	60	3	M42558
Pathway	REACTOME_RHO_GTPASE_CYCLE	SRGAP2 IQGAP1 DLC1 SRGAP3 SYDE2 SRGAP1 ARL13B ARHGAP20	6.04e-04	450	60	8	M27078
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	DRD2 HTR1A HTR1B SSTR2 CHRM3 GPR83	8.08e-04	260	60	6	M39397
Pathway	PID_ILK_PATHWAY	NACA IQGAP1 MYL9	9.16e-04	45	60	3	M71
Pathway	REACTOME_SEROTONIN_RECEPTORS	HTR1A HTR1B	9.56e-04	11	60	2	MM15008
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	DRD2 HTR1A HTR1B SSTR2 CHRM3 GPR83	1.02e-03	272	60	6	M13380
Pathway	REACTOME_SEROTONIN_RECEPTORS	HTR1A HTR1B	1.14e-03	12	60	2	M6034
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	HTR1A HTR1B SSTR2 CHRM3 GPR83	1.15e-03	186	60	5	MM15994
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	SRGAP2 IQGAP1 DLC1 MYL9 SRGAP3 SYDE2 SRGAP1 ARL13B ARHGAP20	1.58e-03	649	60	9	MM15690
Pathway	REACTOME_MRNA_SPLICING	CWC27 PRPF40A SART1 NKAP SRRM2	1.62e-03	201	60	5	MM15411
Pathway	KEGG_MEDICUS_REFERENCE_LESION_BYPASS_BY_TLS_AND_DSB_FORMATION	ERCC4 REV3L	1.81e-03	15	60	2	M47854
Pubmed	TBC1D3, a hominoid oncoprotein, is encoded by a cluster of paralogues located on chromosome 17q12.	TBC1D3E TBC1D3 TBC1D3C TBC1D3K TBC1D3F	1.04e-10	11	105	5	16863688
Pubmed	Inhibition of SRGAP2 function by its human-specific paralogs induces neoteny during spine maturation.	SRGAP2 SRGAP2C SRGAP2B	2.67e-08	3	105	3	22559944
Pubmed	Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system.	SRGAP2 SRGAP3 SRGAP1	2.67e-08	3	105	3	19137586
Pubmed	Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication.	SRGAP2 SRGAP2C SRGAP2B	1.07e-07	4	105	3	22559943
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	MAP7D3 DDX52 NACA LLPH RPS24 DENND2B PRPF40A IQGAP1 SART1 MYL9 UHRF1 PLEC SRRM2 KLHDC4 FTSJ3	1.76e-07	949	105	15	36574265
Pubmed	Characterization of the murine orthologue of a novel human subtelomeric multigene family.	WASHC1 WASH3P WASH2P	2.66e-07	5	105	3	11701968
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TSPYL2 ASH1L HECTD4 APBA1 ZNFX1 SRGAP2 RPS24 DZIP1 REV3L SIM2 IQGAP1 CUEDC1 NEUROD2 SLF2 HPF1 ARL13B PLEC	3.05e-07	1285	105	17	35914814
Pubmed	Human subtelomeric WASH genes encode a new subclass of the WASP family.	WASHC1 WASH3P WASH2P	5.31e-07	6	105	3	18159949
Pubmed	SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.	SRGAP2 SRGAP3 SRGAP1	5.31e-07	6	105	3	33514561
Pubmed	FNBP2 gene on human chromosome 1q32.1 encodes ARHGAP family protein with FCH, FBH, RhoGAP and SH3 domains.	SRGAP2 SRGAP3 SRGAP1	5.31e-07	6	105	3	12736724
Pubmed	Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway.	SRGAP2 SRGAP3 SRGAP1	5.31e-07	6	105	3	11672528
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	STRBP DDX52 DHX57 CHD1 RPS24 PRPF40A IQGAP1 SART1 CTCF PLEC SRRM2 FTSJ3	6.91e-07	653	105	12	22586326
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	LLPH CHD1 RPS24 PRPF40A IQGAP1 SART1 CTCF TNRC6A NKAP PLEC SRRM2 FTSJ3	7.14e-07	655	105	12	35819319
Pubmed	Evidence for a role of srGAP3 in the positioning of commissural axons within the ventrolateral funiculus of the mouse spinal cord.	SRGAP2 SRGAP3 SRGAP1	9.28e-07	7	105	3	21655271
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	STRBP DDX52 LLPH DHX57 ZNFX1 RPS24 PRPF40A SART1 TNRC6A NKAP ZC3H7B SRRM2 FTSJ3	1.01e-06	807	105	13	22681889
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DDX52 TSPYL2 ASH1L REV3L PRPF40A SART1 CTCF BRPF1 LTN1 TNRC6A NKAP CLSPN TOPORS SRRM2 FTSJ3	1.34e-06	1116	105	15	31753913
Pubmed	Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.	WASHC1 WASH3P WASH2P	1.48e-06	8	105	3	10655549
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	CWC27 STRBP DDX52 CHD1 RPS24 PRPF40A IQGAP1 SART1 CTCF UHRF1 PLEC CLSPN SRRM2 FTSJ3	1.72e-06	989	105	14	36424410
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	STRBP DDX52 DHX57 RPS24 PRPF40A IQGAP1 SART1 LTN1 NKTR NKAP SRRM2 FTSJ3	1.72e-06	713	105	12	29802200
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	STRBP DDX52 NACA LLPH DHX57 PRPF40A IQGAP1 ANKRD36B PIK3C2A CTCF TNRC6A UHRF1 NKTR NKAP PLEC FTSJ3	3.58e-06	1371	105	16	36244648
Pubmed	Maternal effects in infant and adult phenotypes of 5HT1A and 5HT1B receptor knockout mice.	HTR1A HTR1B	9.03e-06	2	105	2	12555283
Pubmed	Differential addressing of 5-HT1A and 5-HT1B receptors in epithelial cells and neurons.	HTR1A HTR1B	9.03e-06	2	105	2	10036246
Pubmed	Lack of association or linkage disequilibrium between schizophrenia and polymorphisms in the 5-HT1Dalpha and 5-HT1Dbeta autoreceptor genes: family-based association study.	HTR1A HTR1B	9.03e-06	2	105	2	15211620
Pubmed	Acute serotonin 1B/1A receptor activation impairs behavioral flexibility in C57BL/6J mice.	HTR1A HTR1B	9.03e-06	2	105	2	35367298
Pubmed	Molecular cloning of a human serotonin receptor (S12) with a pharmacological profile resembling that of the 5-HT1D subtype.	HTR1A HTR1B	9.03e-06	2	105	2	1559993
Pubmed	Dopamine D2L Receptor Deficiency Causes Stress Vulnerability through 5-HT1A Receptor Dysfunction in Serotonergic Neurons.	DRD2 HTR1A	9.03e-06	2	105	2	31371425
Pubmed	Identification of SRGAP2 as a potential oncogene and a prognostic biomarker in hepatocellular carcinoma.	SRGAP2 SRGAP1	9.03e-06	2	105	2	33984363
Pubmed	Serotonin receptor 1A knockout: an animal model of anxiety-related disorder.	HTR1A HTR1B	9.03e-06	2	105	2	9826725
Pubmed	[Association study of HTR1A and HTR1B with adolescent idiopathic scoliosis].	HTR1A HTR1B	9.03e-06	2	105	2	20388441
Pubmed	Positive selection of a gene family during the emergence of humans and African apes.	NPIPA1 NPIPA8	9.03e-06	2	105	2	11586358
Pubmed	SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A.	HTR1A HTR1B	9.03e-06	2	105	2	19829169
Pubmed	Operant learning and differential-reinforcement-of-low-rate 36-s responding in 5-HT1A and 5-HT1B receptor knockout mice.	HTR1A HTR1B	9.03e-06	2	105	2	12742250
Pubmed	Sucrose intake and fasting glucose levels in 5-HT(1A) and 5-HT(1B) receptor mutant mice.	HTR1A HTR1B	9.03e-06	2	105	2	18155098
Pubmed	Functional polymorphisms of the 5-HT1A and 5-HT1B receptor are associated with clinical symptoms in migraineurs.	HTR1A HTR1B	9.03e-06	2	105	2	17417740
Pubmed	The human-specific paralogs SRGAP2B and SRGAP2C differentially modulate SRGAP2A-dependent synaptic development.	SRGAP2C SRGAP2B	9.03e-06	2	105	2	31822692
Pubmed	SRGAP2 and Its Human-Specific Paralog Co-Regulate the Development of Excitatory and Inhibitory Synapses.	SRGAP2 SRGAP2C	9.03e-06	2	105	2	27373832
Pubmed	Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse.	HTR1A HTR1B	9.03e-06	2	105	2	11504806
Pubmed	Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse.	HTR1A HTR1B	9.03e-06	2	105	2	11504805
Pubmed	Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice.	HTR1A HTR1B	9.03e-06	2	105	2	11504807
Pubmed	Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments.	HTR1A HTR1B	9.03e-06	2	105	2	21333660
Pubmed	WASH and the Arp2/3 complex regulate endosome shape and trafficking.	WASHC1 WASH3P	9.03e-06	2	105	2	20175130
Pubmed	Slit-Robo GTPase-activating proteins are differentially expressed in murine dorsal root ganglia: modulation by peripheral nerve injury.	SRGAP3 SRGAP1	9.03e-06	2	105	2	22271578
Pubmed	HTR1A/1B DNA methylation may predict escitalopram treatment response in depressed Chinese Han patients.	HTR1A HTR1B	9.03e-06	2	105	2	29275155
Pubmed	Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 Co-immunoprecipitation and fluorescence resonance energy transfer analysis.	DRD2 SSTR2	9.03e-06	2	105	2	17706924
Pubmed	Decreased G-protein coupling of serotonin 5-HT(1A) receptors in the brain of 5-HT(1B) knockout mouse.	HTR1A HTR1B	9.03e-06	2	105	2	12069904
Pubmed	Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout.	HTR1A HTR1B	9.03e-06	2	105	2	11483665
Pubmed	Genetic association of 5-HT1A and 5-HT1B gene polymorphisms with migraine in a Turkish population.	HTR1A HTR1B	9.03e-06	2	105	2	23375453
Pubmed	Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition.	HTR1A HTR1B	9.03e-06	2	105	2	10788764
Pubmed	The inverse F-BAR domain protein srGAP2 acts through srGAP3 to modulate neuronal differentiation and neurite outgrowth of mouse neuroblastoma cells.	SRGAP2 SRGAP3	9.03e-06	2	105	2	23505444
Pubmed	Differential regulation of human dopamine D2 and somatostatin receptor subtype expression by glucocorticoids in vitro.	DRD2 SSTR2	9.03e-06	2	105	2	18852217
Pubmed	Serotonin receptor knockouts: a moody subject.	HTR1A HTR1B	9.03e-06	2	105	2	9860934
Pubmed	The receptor protein-tyrosine phosphatase PTPmu interacts with IQGAP1.	IQGAP1 PTPRM	9.03e-06	2	105	2	16380380
Pubmed	Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration.	AHI1 ARL13B	9.03e-06	2	105	2	31391239
Pubmed	Reappraisal of the serotonin 5-HT(1B) receptor gene in alcoholism: of mice and men.	HTR1A HTR1B	9.03e-06	2	105	2	11827742
Pubmed	The HTR1A and HTR1B receptor genes influence stress-related information processing.	HTR1A HTR1B	9.03e-06	2	105	2	20638825
Pubmed	Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT(1A) or 5-HT(1B) receptor knockout mice.	HTR1A HTR1B	9.03e-06	2	105	2	11080193
Pubmed	Genetics of alcoholism: a review of recent studies in human and animal models.	DRD2 HTR1B	9.03e-06	2	105	2	10598210
Pubmed	Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem-like cells isolated from nonfunctioning pituitary tumors.	DRD2 SSTR2	9.03e-06	2	105	2	28120505
Pubmed	5-HT1A/1B receptors as targets for optimizing pigmentary responses in C57BL/6 mouse skin to stress.	HTR1A HTR1B	9.03e-06	2	105	2	24586946
Pubmed	Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice.	HTR1A HTR1B	9.03e-06	2	105	2	15688089
Pubmed	5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response.	HTR1A HTR1B	9.03e-06	2	105	2	11164514
Pubmed	Somatostatin and dopamine receptor profile of gastroenteropancreatic neuroendocrine tumors: an immunohistochemical study.	DRD2 SSTR2	9.03e-06	2	105	2	21287294
Pubmed	Depressive-like state sensitizes 5-HT1A and 5-HT1B auto-receptors in the dorsal raphe nucleus sub-system.	HTR1A HTR1B	9.03e-06	2	105	2	32360167
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	HECTD4 DHX57 CHD1 RPS24 LTN1 SRRM2 FTSJ3	1.14e-05	250	105	7	33536335
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP7D3 SRGAP2 DZIP1 DENND2B DLC1 MAST4 PIK3C2A SLF2 SYDE2 SRGAP1 PLEC SRRM2	1.17e-05	861	105	12	36931259
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	SRGAP2 SRGAP3 SRGAP1 MYO15A	1.62e-05	50	105	4	19807924
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MAP7D3 STRBP DDX52 NACA DHX57 IQGAP1 SART1 UHRF1 NKAP ZC3H7B FTSJ3	1.93e-05	759	105	11	35915203
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RPS6KA5 PRPF40A IQGAP1 SART1 ZNF644 BRPF1 NKAP PLEC TOPORS SRRM2 KLHDC4	2.31e-05	774	105	11	15302935
Pubmed	[Development of serotonergic neurons of dorsal raphe nuclei in mice with knockout of monoamine oxidase A and 5-HT1A and 5-HT1B autoreceptor].	HTR1A HTR1B	2.70e-05	3	105	2	19705758
Pubmed	A transducible nuclear/nucleolar protein, mLLP, regulates neuronal morphogenesis and synaptic transmission.	LLPH CTCF	2.70e-05	3	105	2	26961175
Pubmed	Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow.	IQGAP1 MYL9	2.70e-05	3	105	2	27104745
Pubmed	Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.	WASHC1 WASH3P	2.70e-05	3	105	2	38086439
Pubmed	Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens.	DRD2 HTR1B	2.70e-05	3	105	2	35545050
Pubmed	Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP.	HTR1A HTR1B	2.70e-05	3	105	2	15009141
Pubmed	Lack of GSK3β activation and modulation of synaptic plasticity by dopamine in 5-HT1A-receptor KO mice.	DRD2 HTR1A	2.70e-05	3	105	2	27678414
Pubmed	Altered serotonin receptor expression is associated with depression-related behavior in the R6/1 transgenic mouse model of Huntington's disease.	HTR1A HTR1B	2.70e-05	3	105	2	19008301
Pubmed	WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.	WASHC1 WASH3P	2.70e-05	3	105	2	30425062
Pubmed	[Comparative Analysis of Polymorphisms of the Serotonin Receptor Genes HTR1A, HTR2A, and HTR1B in Hadza and Datoga Males].	HTR1A HTR1B	2.70e-05	3	105	2	26845861
Pubmed	No association between polymorphisms in four serotonin receptor genes, serotonin transporter gene and alcohol-related suicide.	HTR1A HTR1B	2.70e-05	3	105	2	21169892
Pubmed	Divergent origins and concerted expansion of two segmental duplications on chromosome 16.	NPIPB3 NPIPB5	2.70e-05	3	105	2	11948212
Pubmed	[Involvement of prefrontal serotonergic neurons in methamphetamine-induced behavioral sensitization].	HTR1A HTR1B	2.70e-05	3	105	2	18516987
Pubmed	Serotonin 5-HT1A, 5-HT1B, and 5-HT2A receptor mRNA expression in subjects with major depression, bipolar disorder, and schizophrenia.	HTR1A HTR1B	2.70e-05	3	105	2	14744462
Pubmed	WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.	WASHC1 WASH3P	2.70e-05	3	105	2	25225459
Pubmed	Genetic polymorphisms of the 5HT receptors are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis.	HTR1A HTR1B	2.70e-05	3	105	2	29709878
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	CWC27 NACA SRGAP2 PRPF40A IQGAP1 SART1 PIK3C2A UHRF1 PLEC SRRM2	3.24e-05	660	105	10	32780723
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SRRM4 NACA HECTD4 DZIP1 IQGAP1 MAST4 TNRC6A ZC3H7B ARHGAP20	3.36e-05	529	105	9	14621295
Pubmed	Worldwide genetic variation in dopamine and serotonin pathway genes: implications for association studies.	DRD2 HTR1A HTR1B	3.42e-05	21	105	3	18270970
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	DHX57 ZNFX1 IQGAP1 LTN1 ANKRD30A PLEC	3.56e-05	202	105	6	33005030
Pubmed	The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.	MAP7D3 STRBP DDX52 NACA DHX57 RPS24 SART1 TNRC6A FTSJ3	4.35e-05	547	105	9	37267103
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CWC27 DDX52 NACA LLPH DHX57 CHD1 SRGAP2 IQGAP1 CUEDC1 PIK3C2A CTCF LTN1 TNRC6A NKAP ZC3H7B	4.39e-05	1497	105	15	31527615
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	DDX52 TSPYL2 LLPH CHD1 RPS24 PRPF40A SART1 CTCF BRPF1 SRRM2 FTSJ3	5.22e-05	847	105	11	35850772
Pubmed	Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development.	HTR1A HTR1B	5.40e-05	4	105	2	16824687
Pubmed	Effects of gravity changes on gene expression of BDNF and serotonin receptors in the mouse brain.	HTR1A HTR1B	5.40e-05	4	105	2	28591153
Pubmed	An association study of the serotonin transporter and receptor genes with the suicidal ideation of major depression in a Chinese Han population.	HTR1A HTR1B	5.40e-05	4	105	2	19897250
Pubmed	WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.	WASHC1 WASH3P	5.40e-05	4	105	2	23275443
Pubmed	[Association of several polymorphic loci of serotoninergic genes with unipolar depression].	HTR1A HTR1B	5.40e-05	4	105	2	19639876
Pubmed	Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation.	WASHC1 WASH3P	5.40e-05	4	105	2	32492429
Pubmed	Novel retinal and cone photoreceptor transcripts revealed by human macular expression profiling.	NPIPA1 NPIPA5	5.40e-05	4	105	2	18055785
Pubmed	PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer.	TBC1D3 TBC1D3F	5.40e-05	4	105	2	12359748
Pubmed	Expression of serotonin receptors 5-HT1A, 5-HT1B, 5-HT2B and 5-HT4 in ovary and in ovarian tumours.	HTR1A HTR1B	5.40e-05	4	105	2	22493371
Interaction	ZCCHC10 interactions	EAPP TSPYL2 DZIP1 PRPF40A ANKRD36B SART1 NKTR NKAP TOPORS SRRM2	2.28e-07	236	98	10	int:ZCCHC10
Interaction	RPL15 interactions	SOX2 TSPYL2 ASH1L LLPH DHX57 RPS24 CUEDC1 RNF151 CTCF NKTR TOPORS FTSJ3	1.01e-05	530	98	12	int:RPL15
Interaction	DHX8 interactions	EAPP CWC27 CHD1 PRPF40A SART1 NKTR NKAP SRRM2 FTSJ3	1.27e-05	292	98	9	int:DHX8
Interaction	LYAR interactions	SOX2 AHI1 ERCC4 GRK5 DHX57 RPS24 CTCF NKAP SRRM2 FTSJ3	1.38e-05	373	98	10	int:LYAR
Interaction	SAP18 interactions	GRK5 PRPF40A IQGAP1 SART1 CTCF LTN1 NKTR TOPORS SRRM2	1.79e-05	305	98	9	int:SAP18
Interaction	DDX23 interactions	EAPP CWC27 DDX52 CHD1 PRPF40A SART1 BRPF1 NKTR NKAP SRRM2 FTSJ3	2.17e-05	480	98	11	int:DDX23
Interaction	RNF151 interactions	TSPYL2 RNF151 CTCF NKTR SRRM2 FTSJ3	3.04e-05	123	98	6	int:RNF151
Interaction	ZNF324B interactions	DDX52 TSPYL2 DHX57 ZNF644 TOPORS	7.37e-05	89	98	5	int:ZNF324B
Interaction	RAD18 interactions	STRBP CHD1 SART1 SLF2 CTCF SRGAP3 SRGAP1 UHRF1 NKAP SRRM2	7.69e-05	457	98	10	int:RAD18
Interaction	NKTR interactions	RNF151 SRGAP3 SRGAP1 NKTR NKAP	7.78e-05	90	98	5	int:NKTR
Interaction	SNRNP70 interactions	STRBP DDX52 SRRM4 DHX57 RPS24 PRPF40A IQGAP1 SART1 SRGAP1 LTN1 NKTR NKAP ARHGAP20 SRRM2 FTSJ3	7.85e-05	984	98	15	int:SNRNP70
Interaction	RPL4 interactions	SOX2 DDX52 GRK5 TSPYL2 LLPH DHX57 RPS24 PRPF40A IQGAP1 SART1 RNF151 CTCF FTSJ3	8.31e-05	764	98	13	int:RPL4
Interaction	SRRM2 interactions	EAPP CWC27 GRK5 PRPF40A IQGAP1 SART1 RNF151 NKAP PLEC SRRM2	8.41e-05	462	98	10	int:SRRM2
Interaction	ZC3H18 interactions	DDX52 NACA TSPYL2 LLPH RPS24 PRPF40A IQGAP1 SART1 CTCF NKTR NKAP TOPORS SRRM2 FTSJ3	8.57e-05	877	98	14	int:ZC3H18
Interaction	YWHAG interactions	SOX2 MAP7D3 GRK5 HECTD4 SRGAP2 DZIP1 DENND2B PRPF40A IQGAP1 DLC1 MAST4 PIK3C2A SYDE2 SRGAP1 NKTR NKAP SRRM2	1.00e-04	1248	98	17	int:YWHAG
Interaction	SRSF4 interactions	SOX2 SRRM4 DHX57 SART1 CTCF NKTR TOPORS SRRM2	1.08e-04	300	98	8	int:SRSF4
Interaction	OASL interactions	SOX2 STRBP ASH1L LLPH DHX57 PIK3C2A FTSJ3	1.09e-04	223	98	7	int:OASL
Interaction	RNF113A interactions	LLPH CHD1 RPS24 PRPF40A IQGAP1 SART1 CTCF TNRC6A NKAP PLEC SRRM2 FTSJ3	1.33e-04	692	98	12	int:RNF113A
Interaction	POLR1G interactions	CWC27 STRBP DDX52 CHD1 CTCF ZNF644 BRPF1 CLSPN SRRM2 FTSJ3	1.34e-04	489	98	10	int:POLR1G
Interaction	HTR1D interactions	HTR1A HTR1B	1.40e-04	4	98	2	int:HTR1D
Interaction	BRD3 interactions	TSPYL2 CHD1 PRPF40A SART1 CTCF UHRF1 NKAP TOPORS SRRM2 FTSJ3	1.46e-04	494	98	10	int:BRD3
Interaction	FASLG interactions	SRGAP2 PRPF40A SRGAP3 SRGAP1 MYO15A	1.61e-04	105	98	5	int:FASLG
Interaction	U2AF1 interactions	SRRM4 RPS24 PRPF40A SART1 NKAP SRRM2 FTSJ3	1.67e-04	239	98	7	int:U2AF1
Interaction	H1-1 interactions	RPS6KA5 DDX52 DHX57 RPS24 REV3L IQGAP1 RNF151 CTCF DGKI FTSJ3	1.80e-04	507	98	10	int:H1-1
Interaction	DDX21 interactions	SOX2 STRBP GRK5 LLPH DHX57 RPS24 PRPF40A SART1 CTCF ZC3H7B SRRM2 FTSJ3	1.88e-04	718	98	12	int:DDX21
Interaction	SNIP1 interactions	SRRM4 TSPYL2 RPS24 PRPF40A NKTR NKAP TOPORS SRRM2 FTSJ3	1.98e-04	417	98	9	int:SNIP1
Interaction	ARHGAP42 interactions	NACA SRGAP2 SRGAP1 PLEC	2.08e-04	60	98	4	int:ARHGAP42
Interaction	CSNK2B interactions	RPS6KA5 TSPYL2 IQGAP1 CTCF ZNF644 BRPF1 NKTR NKAP CLSPN TOPORS FTSJ3	2.27e-04	625	98	11	int:CSNK2B
Interaction	ZNF467 interactions	STRBP TSPYL2 DHX57 UHRF1 NKTR FTSJ3	2.42e-04	179	98	6	int:ZNF467
Interaction	PUM3 interactions	SOX2 DDX52 LLPH RPS24 RNF151 CTCF FTSJ3	2.43e-04	254	98	7	int:PUM3
Interaction	PRC1 interactions	STRBP DDX52 NACA CHD1 RPS24 PRPF40A IQGAP1 SART1 MYL9 CTCF UHRF1 PLEC SRRM2 FTSJ3	2.53e-04	973	98	14	int:PRC1
Interaction	SIRT7 interactions	STRBP DDX52 DHX57 CHD1 RPS24 PRPF40A IQGAP1 SART1 CTCF PLEC SRRM2 FTSJ3	2.60e-04	744	98	12	int:SIRT7
Interaction	SNRNP40 interactions	STRBP DDX52 CHD1 PRPF40A SART1 CTCF ZNF644 NKTR SAGE1 SRRM2 FTSJ3	2.68e-04	637	98	11	int:SNRNP40
Interaction	HECTD1 interactions	MAP7D3 STRBP DDX52 NACA DHX57 SRGAP2 PRPF40A IQGAP1 SART1 UHRF1 NKAP ZC3H7B PCDH10 FTSJ3	2.84e-04	984	98	14	int:HECTD1
Interaction	SREK1IP1 interactions	PRPF40A RNF151 NKAP SRRM2	3.01e-04	66	98	4	int:SREK1IP1
Interaction	MNDA interactions	STRBP DDX52 LLPH DHX57 CTCF FTSJ3	3.15e-04	188	98	6	int:MNDA
Interaction	WASHC2A interactions	SOX2 WASHC1 WASH3P LTN1 SRRM2	3.24e-04	122	98	5	int:WASHC2A
Interaction	PRPF19 interactions	SOX2 EAPP CWC27 RPS24 SART1 MYL9 LTN1 NKTR SRRM2	3.46e-04	450	98	9	int:PRPF19
Cytoband	Ensembl 112 genes in cytogenetic band chr17q12	TBC1D3E TBC1D3 DDX52 TBC1D3C NEUROD2 TBC1D3K TBC1D3F	5.74e-08	149	105	7	chr17q12
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	NPIPB7 NPIPB4 NPIPB3 NPIPB5 NPIPA8 TNRC6A	3.00e-06	172	105	6	chr16p12
Cytoband	16p11.2	NPIPB7 NPIPB12 NPIPB11 NPIPB13 TNRC6A	8.15e-05	191	105	5	16p11.2
Cytoband	17q12	TBC1D3 TBC1D3C NEUROD2 TBC1D3F	8.23e-05	99	105	4	17q12
Cytoband	16p12.2	NPIPB4 NPIPB3 NPIPB5	8.54e-05	37	105	3	16p12.2
Cytoband	Ensembl 112 genes in cytogenetic band chr16p13	ERCC4 NPIPA1 NPIPA7 RNF151 NPIPA5 SRRM2	4.58e-04	426	105	6	chr16p13
Cytoband	Ensembl 112 genes in cytogenetic band chr5q12	HTR1A CWC27 MAST4	4.79e-04	66	105	3	chr5q12
Cytoband	5q12.3	CWC27 MAST4	7.74e-04	18	105	2	5q12.3
Cytoband	16p13.11	NPIPA1 NPIPA5	1.27e-03	23	105	2	16p13.11
Cytoband	Ensembl 112 genes in cytogenetic band chr16p11	NPIPB12 NPIPB9 NPIPB11 NPIPB13	3.90e-03	278	105	4	chr16p11
GeneFamily	Rho GTPase activating proteins\|F-BAR domain containing	SRGAP2 SRGAP2C SRGAP3 SRGAP1 SRGAP2B	9.17e-09	23	58	5	1288
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	SRGAP2 DLC1 SRGAP3 SRGAP1 ARHGAP20	5.40e-07	50	58	5	721
GeneFamily	Wiskott-Aldrich Syndrome protein family	WASHC1 WASH3P WASH2P	1.70e-05	16	58	3	14
GeneFamily	5-hydroxytryptamine receptors, G protein-coupled	HTR1A HTR1B	7.71e-04	13	58	2	170
GeneFamily	Cyclophilin peptidylprolyl isomerases	CWC27 NKTR	1.67e-03	19	58	2	909
GeneFamily	PHD finger proteins	ASH1L BRPF1 UHRF1	3.02e-03	90	58	3	88
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 SRGAP2 SRGAP2C MYL9 DACH2 SRGAP1 SRGAP2B	2.13e-07	177	105	7	4d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 SRGAP2 SRGAP2C MYL9 DACH2 SRGAP1 SRGAP2B	2.21e-07	178	105	7	edc7143dc9959d36057cb9471681a23afcbc8cce
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	GRK5 APBA1 SRGAP2 SRGAP2C MYL9 DACH2 SRGAP2B	2.67e-07	183	105	7	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	APBA1 SRGAP2 SRGAP2C MYL9 DACH2 SRGAP1 SRGAP2B	2.67e-07	183	105	7	848fc6dd129150897ee339343e83c645b6e779eb
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 APBA1 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	2.87e-07	185	105	7	b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCell	moderate-Epithelial-unknown_epithelial\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	AHI1 NPIPB11 TCIM TSPYL2 RNF151 TBC1D3F	6.60e-07	130	105	6	a04057bd4f256d09eca06b8c1e8b41425bb4ef3f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	3.37e-06	172	105	6	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	APBA1 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	4.23e-06	179	105	6	7394e77e665bf16d3733df91bb12907be460ab44
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 SRGAP2C MYL9 DACH2 SRGAP2B ARHGAP20	4.37e-06	180	105	6	d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	APBA1 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	4.51e-06	181	105	6	5bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	NPIPB4 TSPYL2 ASH1L ANKRD36B NKTR SRGAP2B	4.51e-06	181	105	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	APBA1 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	4.51e-06	181	105	6	8e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 APBA1 SRGAP2 SRGAP2C DACH2 SRGAP2B	4.81e-06	183	105	6	3c516fe5083f02bad1f464ed284010b4131a833c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	4.81e-06	183	105	6	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 APBA1 SRGAP2 SRGAP2C DACH2 SRGAP2B	4.81e-06	183	105	6	9c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	APBA1 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	4.81e-06	183	105	6	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	5.12e-06	185	105	6	9197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 SRGAP2 SRGAP2C DACH2 SRGAP1 SRGAP2B	5.12e-06	185	105	6	ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CHD1 REV3L SRGAP2C SRGAP3 NKTR SRGAP2B	5.44e-06	187	105	6	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	NPIPB4 TSPYL2 ASH1L CHD1 ZNF644 NKTR	5.61e-06	188	105	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 SRGAP2C MYL9 DACH2 SRGAP1 SRGAP2B	5.61e-06	188	105	6	047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRBP ASH1L PRPF40A IQGAP1 CTCF ARHGAP20	6.14e-06	191	105	6	60c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	AHI1 TSPYL2 CHD1 ZNF644 NKTR SRRM2	6.14e-06	191	105	6	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHI1 CHD1 SLF2 NKTR ARHGAP20 SRRM2	6.14e-06	191	105	6	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRBP ASH1L PRPF40A IQGAP1 CTCF ARHGAP20	6.14e-06	191	105	6	09db184cb90fe282a14474d7217068c58092c6f8
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STRBP ASH1L PRPF40A IQGAP1 CTCF ARHGAP20	6.14e-06	191	105	6	973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	NPIPB4 TSPYL2 ASH1L CHD1 ANKRD36B NKTR	6.33e-06	192	105	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 SRGAP2C MYL9 DACH2 SRGAP1 SRGAP2B	6.52e-06	193	105	6	3eaa0461618582a1754400624350d269d24e750a
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AHI1 ASH1L CHD1 NKTR ARHGAP20 SRRM2	6.92e-06	195	105	6	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AHI1 STRBP SRRM4 CHRM3 ANKRD36B DGKI	7.12e-06	196	105	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 REV3L DENND2B DLC1 MYL9 DACH2	7.12e-06	196	105	6	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AHI1 STRBP SRRM4 CHRM3 ANKRD36B DGKI	7.55e-06	198	105	6	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	NPIPB4 TSPYL2 ASH1L NPIPB5 ZNF644 NKTR	7.77e-06	199	105	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ASH1L DLC1 MAST4 PTPRM PIK3C2A NKTR	7.99e-06	200	105	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	AHI1 STRBP SRRM4 CHRM3 ANKRD36B DGKI	7.99e-06	200	105	6	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SOX2 NPIPB15 CHRM3 DACH2 SRGAP3 SRGAP1	7.99e-06	200	105	6	ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	NPIPB4 TSPYL2 ASH1L SSTR2 NKTR	1.01e-05	121	105	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	NS-critical-d_07-13-Epithelial-unknown_epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AHI1 TCIM TSPYL2 HECTD4 TBC1D3C	2.11e-05	141	105	5	33ad925ff7be3c682741a6328216a89f9d4033e9
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX2 DRD2 HTR1A GPR83 PTPRM	3.23e-05	154	105	5	a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCell	10x5'-bone_marrow-Mast\|bone_marrow / Manually curated celltypes from each tissue	TRPM6 NPIPB15 DLC1 SRGAP3 DGKI	3.76e-05	159	105	5	c3d3570e83c5d25cc92fa3a7a8f0dc2f89a72913
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Lsp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SOX2 GRK5 PTPRM SYDE2 SRGAP1	3.76e-05	159	105	5	0dccc4275b9b4f8554dd556da7218e130bff8fd1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1S GRK5 SRGAP2 SRGAP2C DACH2	4.88e-05	168	105	5	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 SRGAP2 SRGAP2C DACH2 SRGAP2B	5.77e-05	174	105	5	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	COVID-19-kidney-Podocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	APBA1 SRGAP2 SRGAP2C DACH2 SRGAP2B	5.93e-05	175	105	5	a73e3a65fd5c1e09cb0c2dae20c1a7bfcae49223
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPIPB15 ANKRD36B SRGAP3 SRGAP1 NKTR	6.60e-05	179	105	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX2 NPIPB15 TSPYL2 NPIPA5 PDZD4	6.77e-05	180	105	5	e4add4c94f892a2d93926e5c6dac6a738319d091
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNA1S SRGAP2C MYL9 DACH2 SRGAP2B	7.14e-05	182	105	5	cde8fa4f42d25545abaa9ee885b4b1e24a5a8e08
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-intermediate_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SOX2 DRD2 SRRM4 SSTR2 DACH2	7.51e-05	184	105	5	9e5f98f9113e5e38bdadba6d9d2c346177fb35fe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	APBA1 SRGAP2 SRGAP2C DACH2 SRGAP2B	7.51e-05	184	105	5	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LLPH RPS24 UHRF1 CLSPN SRRM2	7.91e-05	186	105	5	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NPIPB11 DACH2 NPIPB13 SRGAP1 PLEC	7.91e-05	186	105	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LLPH RPS24 UHRF1 CLSPN SRRM2	7.91e-05	186	105	5	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	PRPF40A PIK3C2A CTCF ZNF644 LTN1	7.91e-05	186	105	5	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2 SRGAP2C MYL9 DACH2 SRGAP2B	8.32e-05	188	105	5	9db778c1d9e622a68337212296e3a1ed8f771fa5
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	GRK5 DLC1 PTPRM PIK3C2A DGKI	8.53e-05	189	105	5	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	Non-neuronal-Postmitotic-Red_blood_cells-Low_Quality\|World / Primary Cells by Cluster	SRRM4 NACA HECTD4 RPS24 SRGAP1	8.74e-05	190	105	5	31cf1367db5c04242621f7c98a10d094bc519e31
ToppCell	Non-neuronal-Postmitotic-Red_blood_cells\|World / Primary Cells by Cluster	SRRM4 NACA HECTD4 RPS24 SRGAP1	8.74e-05	190	105	5	f0b82334375749d917e440c493f10340c52ea13c
ToppCell	Non-neuronal-Postmitotic-Red_blood_cells-Low_Quality-14\|World / Primary Cells by Cluster	SRRM4 NACA HECTD4 RPS24 SRGAP1	8.74e-05	190	105	5	feadd834d843f952aa7ced93899fd1f0868743df
ToppCell	390C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	AHI1 RPS6KA5 TSPYL2 DLC1 MAST4	9.18e-05	192	105	5	201d430af1e4fee7bc03baf0aca17db26f6f439a
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SRGAP2C MYL9 DACH2 SRGAP1 SRGAP2B	9.18e-05	192	105	5	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	390C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	AHI1 RPS6KA5 TSPYL2 DLC1 MAST4	9.18e-05	192	105	5	15c1a0a0d07106118427135f166a1da710bf621a
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NPIPB4 NPIPB3 NPIPB5 PTPRM DGKI	9.41e-05	193	105	5	779276e775cb2492e8dd36436295a536084a6415
ToppCell	Control-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	GRK5 CHD1 SRGAP2 SRGAP2C SRGAP2B	9.41e-05	193	105	5	3479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GRK5 DLC1 MAST4 SRGAP3 ARHGAP20	9.64e-05	194	105	5	99577a5a631e607b5abe7a1b0d8d6a5eabe50196
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GRK5 DLC1 MAST4 DACH2 PTPRM	9.64e-05	194	105	5	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 DENND2B DLC1 MYL9 DACH2	9.64e-05	194	105	5	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 DENND2B DLC1 MYL9 DACH2	9.64e-05	194	105	5	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GRK5 DLC1 MAST4 SRGAP3 ARHGAP20	9.87e-05	195	105	5	70387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 REV3L DENND2B DLC1 DACH2	9.87e-05	195	105	5	803f714d91f2d97ecbee8c15a5139fd9310f66c7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L REV3L IQGAP1 NKTR SRRM2	9.87e-05	195	105	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 REV3L DENND2B DLC1 DACH2	9.87e-05	195	105	5	4f70157d42a16ff0259bc24a62803c4df4285c44
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASH1L REV3L IQGAP1 NKTR SRRM2	9.87e-05	195	105	5	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	GRK5 TCIM MAST4 PTPRM PIK3C2A	1.04e-04	197	105	5	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GRK5 DENND2B DLC1 MYL9 DACH2	1.04e-04	197	105	5	80e153790cef37b743e22a7370ff5b3a6abf147d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GRK5 DLC1 MAST4 SRGAP3 ARHGAP20	1.04e-04	197	105	5	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	AHI1 PRPF40A NKTR CLSPN SRRM2	1.04e-04	197	105	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AHI1 STRBP SRRM4 CHRM3 DGKI	1.06e-04	198	105	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AHI1 STRBP SRRM4 CHRM3 DGKI	1.06e-04	198	105	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	AHI1 STRBP SRRM4 CHRM3 DGKI	1.06e-04	198	105	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAP7D3 GRK5 SSTR2 DLC1 MYL9	1.06e-04	198	105	5	b7e900fc0a1b3fa5e47dcc36ce6b0c3ce6bf9739
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-Neurons\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SRRM4 SSTR2 NEUROD2 TRAM1L1 SRGAP1	1.09e-04	199	105	5	0c5a5fbb174a013be10961f0db65c65c797ab4af
ToppCell	Transverse-T_cell-Tfh\|Transverse / Region, Cell class and subclass	TSPYL2 APBA1 PTPRM SRGAP1 TOPORS	1.09e-04	199	105	5	cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	SRRM4 SSTR2 NEUROD2 TRAM1L1 SRGAP1	1.09e-04	199	105	5	b2508bf591720830e8e3494b1337aab14539956d
ToppCell	Transverse-(1)_T_cell-(16)_Tfh\|Transverse / shred on region, Cell_type, and subtype	TSPYL2 APBA1 PTPRM SRGAP1 TOPORS	1.09e-04	199	105	5	aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCell	LPS_anti-TNF-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TRPM6 SELL CHRM3 UHRF1 CLSPN	1.11e-04	200	105	5	0b02f3ca3d8612ed7af46381195b0ed5591313cf
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SOX2 AHI1 STRBP DENND2B SRGAP3	1.11e-04	200	105	5	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	SOX2 CHRM3 DACH2 SRGAP3 SRGAP1	1.11e-04	200	105	5	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	SRRM4 SSTR2 NEUROD2 DACH2 SRGAP1	1.11e-04	200	105	5	f6d6a2f4e2f51c292dfb97280353a49117798fc6
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ASH1L CHD1 ZNF644 NKTR SRRM2	1.11e-04	200	105	5	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	RPS6KA5 STRBP CHRM3 MAST4 PCDH10	1.11e-04	200	105	5	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	SOX2 TCIM NEUROD2 SRGAP3 SRGAP1	1.11e-04	200	105	5	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SOX2 NPIPB15 CHRM3 SRGAP3 SRGAP1	1.11e-04	200	105	5	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	Control-Developping_Plasmablast\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SPATA3 NPIPB7 DZIP1 CLSPN	1.87e-04	120	105	4	695dab6b01ad2c33cdcaf92bb9996ff2899ef77e
ToppCell	COVID-19_Mild-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	DENND2B NPIPA8 NPIPA5 ANKRD30A	2.12e-04	124	105	4	5ef9eb806fb2c8ee5aae0a75503d244b08ee10d4
Drug	SDZ 208-911	DRD2 HTR1A HTR1B	7.45e-07	5	97	3	CID000148841
Drug	mazapertine	DRD2 HTR1A HTR1B	7.45e-07	5	97	3	CID000060819
Drug	cinuperone	DRD2 HTR1A HTR1B	7.45e-07	5	97	3	CID000133831
Drug	AC1N7C9F	DRD2 HTR1A HTR1B	1.49e-06	6	97	3	CID000711932
Drug	lofepramine	DRD2 HTR1A CHRM3 PLEC	2.58e-06	23	97	4	CID000003947
Drug	BRL 34778	DRD2 HTR1A HTR1B	2.59e-06	7	97	3	CID000135770
Drug	Olanzapine	DRD2 HTR1A HTR1B CHRM3	3.66e-06	25	97	4	DB00334
Drug	Ziprasidone	DRD2 HTR1A HTR1B CHRM3	3.66e-06	25	97	4	DB00246
Drug	Aripiprazole	DRD2 HTR1A HTR1B CHRM3	3.66e-06	25	97	4	DB01238
Drug	AC1L5AAF	DRD2 HTR1A HTR1B	4.13e-06	8	97	3	CID000173615
Drug	SB215,505	DRD2 HTR1A HTR1B	4.13e-06	8	97	3	CID006603999
Drug	Clozapine	DRD2 HTR1A HTR1B CHRM3	4.31e-06	26	97	4	DB00363
Drug	Quetiapine	DRD2 HTR1A HTR1B CHRM3	4.31e-06	26	97	4	DB01224
Drug	T15550	DRD2 HTR1A HTR1B CHRM3	4.31e-06	26	97	4	CID000005454
Drug	melantonin	DRD2 HTR1A HTR1B	6.18e-06	9	97	3	CID000077899
Drug	AC1L9S9A	DRD2 HTR1A HTR1B	6.18e-06	9	97	3	CID000475096
Drug	CQ 32-084	DRD2 HTR1A HTR1B	6.18e-06	9	97	3	CID000068847
Drug	U91356A	DRD2 HTR1A HTR1B	6.18e-06	9	97	3	CID000132955
Drug	Rds-127	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	CID000134064
Drug	5-OH-DPAT	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	CID000172267
Drug	CM 29-712	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	CID000159842
Drug	Yohimbine	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	DB01392
Drug	2-(di-n-propylamino)tetralin	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	CID000090285
Drug	S 14297	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	CID000115007
Drug	U-86170F	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	CID000131559
Drug	SDZ 208-912	DRD2 HTR1A HTR1B	8.80e-06	10	97	3	CID000058145
Drug	xanomeline	DRD2 HTR1A HTR1B CHRM3	8.92e-06	31	97	4	CID000060809
Drug	eticlopride	DRD2 HTR1A HTR1B SSTR2	1.02e-05	32	97	4	CID000057266
Drug	mesoridazine	DRD2 HTR1A HTR1B CHRM3	1.15e-05	33	97	4	CID000004078
Drug	MK-771	DRD2 HTR1A HTR1B	1.21e-05	11	97	3	CID000123992
Drug	S 14506	DRD2 HTR1A HTR1B	1.60e-05	12	97	3	CID000131905
Drug	ocaperidone	DRD2 HTR1A HTR1B	1.60e-05	12	97	3	CID000071351
Drug	molindone	DRD2 HTR1A HTR1B CHRM3	1.64e-05	36	97	4	CID000023897
Drug	Piperazinehexanamide derivative, 12	DRD2 HTR1A	1.80e-05	2	97	2	CID011385991
Drug	Piperazinehexanamide derivative, 10	DRD2 HTR1A	1.80e-05	2	97	2	CID011431529
Drug	Buspirone	DRD2 HTR1A	1.80e-05	2	97	2	DB00490
Drug	8-methoxy-2'-chloro-PAT	HTR1A HTR1B	1.80e-05	2	97	2	CID000125955
Drug	SureCN4460956	DRD2 HTR1A	1.80e-05	2	97	2	CID011191127
Drug	Piperazinehexanamide derivative, 13	DRD2 HTR1A	1.80e-05	2	97	2	CID011248331
Drug	5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole	HTR1A HTR1B	1.80e-05	2	97	2	ctd:C025145
Drug	Lp44	DRD2 HTR1A	1.80e-05	2	97	2	CID011224758
Drug	1,4-benzoxazepine	DRD2 HTR1A	1.80e-05	2	97	2	CID014712340
Drug	8-Azabicyclo[3.2.1]oct-2-ene	HTR1A HTR1B	1.80e-05	2	97	2	CID000138546
Drug	N-propylnoraporphin-11-yl 5-(1,2-dithiolan-3-yl)pentanoate	DRD2 HTR1A	1.80e-05	2	97	2	ctd:C561226
Drug	3-(4-piperidyl)-1H-indole	HTR1A HTR1B	1.80e-05	2	97	2	CID000702235
Drug	SureCN4462276	DRD2 HTR1A	1.80e-05	2	97	2	CID011282296
Drug	Piperazinehexanamide derivative, 11	DRD2 HTR1A	1.80e-05	2	97	2	CID011329253
Drug	tertatolol	HTR1A HTR1B	1.80e-05	2	97	2	ctd:C005632
Drug	GR 46611	HTR1A HTR1B	1.80e-05	2	97	2	ctd:C119994
Drug	(3-exo)-8-benzoyl-N-(((2S)7-chloro-2,3-dihydro-1,4-benzodioxin-1-yl)methyl)-8-azabicyclo(3.2.1)octane-3-methanamine monohydrochloride	DRD2 HTR1A	1.80e-05	2	97	2	ctd:C480819
Drug	RU 23686	HTR1A HTR1B	1.80e-05	2	97	2	CID000043223
Drug	SureCN4464192	DRD2 HTR1A	1.80e-05	2	97	2	CID011785182
Drug	p-azido-PAPP	HTR1A HTR1B	1.80e-05	2	97	2	CID000128737
Drug	pardoprunox	DRD2 HTR1A	1.80e-05	2	97	2	ctd:C480679
Drug	8-methoxy-3'-NAP-amino-PAT	HTR1A HTR1B	1.80e-05	2	97	2	CID003035902
Drug	Anabolic Agents	HTR1A HTR1B	1.80e-05	2	97	2	ctd:D045930
Drug	8-MeO-CLEPAT	HTR1A HTR1B	1.80e-05	2	97	2	CID000183772
Drug	SureCN4458829	DRD2 HTR1A	1.80e-05	2	97	2	CID011432176
Drug	benzotropine mesylate	DRD2 HTR1B CHRM3 PIK3C2A	1.84e-05	37	97	4	CID000002344
Drug	promazine	DRD2 HTR1A HTR1B CHRM3	1.84e-05	37	97	4	CID000004926
Drug	Cefuroxime sodium salt [56238-63-2]; Up 200; 9uM; MCF7; HT_HG-U133A	AHI1 APBA1 CHRM3 CUEDC1 DLC1 MAST4 NKTR	2.17e-05	197	97	7	6261_UP
Drug	Propidium iodide [25535-16-4]; Down 200; 6uM; MCF7; HT_HG-U133A	SOX2 DRD2 ERCC4 CHRM3 DENND2B DLC1 ZC3H7B	2.24e-05	198	97	7	6104_DN
Drug	1ndw	HTR1A ERCC4 APBA1 DENND2B	2.27e-05	39	97	4	CID000447340
Drug	Lisuride	DRD2 HTR1A HTR1B	2.64e-05	14	97	3	DB00589
Drug	Pramipexole	DRD2 HTR1A HTR1B	2.64e-05	14	97	3	DB00413
Drug	Ropinirole	DRD2 HTR1A HTR1B	2.64e-05	14	97	3	DB00268
Drug	Saphris	DRD2 HTR1A HTR1B CHRM3	2.78e-05	41	97	4	CID000163091
Drug	Cabergoline	DRD2 HTR1A HTR1B	3.29e-05	15	97	3	DB00248
Drug	Apomorphine	DRD2 HTR1A HTR1B	3.29e-05	15	97	3	DB00714
Drug	PD 128907	DRD2 HTR1A HTR1B	3.29e-05	15	97	3	CID000005117
Drug	loxapine	DRD2 HTR1A HTR1B CHRM3	4.40e-05	46	97	4	CID000003964
Drug	B-HT 920	DRD2 HTR1A HTR1B PIK3C2A	4.80e-05	47	97	4	CID000005374
Drug	N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide	DRD2 HTR1A HTR1B	4.88e-05	17	97	3	ctd:C090413
Drug	Pergolide	DRD2 HTR1A HTR1B	4.88e-05	17	97	3	DB01186
Drug	aporphine	DRD2 HTR1A HTR1B	4.88e-05	17	97	3	CID000114911
Drug	S 15535	DRD2 HTR1A HTR1B	4.88e-05	17	97	3	CID000132787
Drug	Remoxipride	DRD2 HTR1A	5.37e-05	3	97	2	ctd:D017330
Drug	batoprazine	HTR1A HTR1B	5.37e-05	3	97	2	CID000184839
Drug	4-phenylquinoline	HTR1A HTR1B	5.37e-05	3	97	2	CID000521929
Drug	CI-926	HTR1A HTR1B	5.37e-05	3	97	2	CID000128627
Drug	5-carboxamidotryptamine	HTR1A HTR1B	5.37e-05	3	97	2	ctd:C047087
Drug	JB-788	DRD2 HTR1A	5.37e-05	3	97	2	ctd:C554161
Drug	spirilene	HTR1A HTR1B	5.37e-05	3	97	2	CID006436870
Drug	lurasidone	DRD2 HTR1A	5.37e-05	3	97	2	CID000213046
Drug	fluprazine	HTR1A HTR1B	5.37e-05	3	97	2	CID000071153
Drug	lysergic acid amide	DRD2 HTR1A	5.37e-05	3	97	2	CID000010173
Drug	WAY-100635	DRD2 HTR1A HTR1B TCIM	5.66e-05	49	97	4	CID000005684
Drug	zotepine	DRD2 HTR1A HTR1B CHRM3	5.66e-05	49	97	4	CID000005736
Drug	Bromocriptine	DRD2 HTR1A HTR1B	5.84e-05	18	97	3	DB01200
Drug	sertindole	DRD2 HTR1A HTR1B CHRM3	6.13e-05	50	97	4	CID000060149
Drug	tiospirone	DRD2 HTR1A HTR1B	6.91e-05	19	97	3	CID000055751
Drug	SB 200646A	DRD2 HTR1A HTR1B	6.91e-05	19	97	3	CID000126769
Drug	MDL 11,939	DRD2 HTR1A HTR1B	6.91e-05	19	97	3	CID000071781
Drug	femoxitine	DRD2 HTR1A CHRM3	6.91e-05	19	97	3	CID000043103
Drug	S-20499	DRD2 HTR1A HTR1B	6.91e-05	19	97	3	CID000121851
Drug	RP 62203	DRD2 HTR1A HTR1B	6.91e-05	19	97	3	CID000060785
Drug	perphenazine	DRD2 HTR1A HTR1B CHRM3	7.72e-05	53	97	4	CID000004748
Drug	Doxepin	DRD2 HTR1A CHRM3	8.11e-05	20	97	3	DB01142
Drug	SCH 39166	DRD2 HTR1A HTR1B	8.11e-05	20	97	3	CID000107930
Drug	Photofrin	DRD2 HTR1A HTR1B	9.43e-05	21	97	3	CID000057166
Disease	cysteine-rich with EGF-like domain protein 1 measurement	SRGAP2 SRGAP3 BRPF1	1.23e-04	32	89	3	EFO_0021870
Disease	anxiety disorder (is_implicated_in)	DRD2 HTR1A	1.34e-04	6	89	2	DOID:2030 (is_implicated_in)
Disease	generalized anxiety disorder (implicated_via_orthology)	HTR1A HTR1B	2.49e-04	8	89	2	DOID:14320 (implicated_via_orthology)
Disease	Visual seizure	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0270824
Disease	Epileptic drop attack	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0270846
Disease	Generalized seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0234533
Disease	Clonic Seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0234535
Disease	Vertiginous seizure	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0422855
Disease	Gustatory seizure	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0422854
Disease	Seizures, Somatosensory	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0422850
Disease	Olfactory seizure	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0422853
Disease	Seizures, Auditory	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0422852
Disease	Generalized Absence Seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C4505436
Disease	Convulsive Seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0751494
Disease	Seizures, Sensory	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0751496
Disease	Jacksonian Seizure	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0022333
Disease	Non-epileptic convulsion	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0751056
Disease	Atonic Absence Seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0751123
Disease	Complex partial seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0149958
Disease	Single Seizure	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C0751110
Disease	Epileptic Seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C4317109
Disease	Nonepileptic Seizures	DRD2 HTR1A HTR1B SSTR2	2.53e-04	101	89	4	C3495874
Disease	Tonic Seizures	DRD2 HTR1A HTR1B SSTR2	2.62e-04	102	89	4	C0270844
Disease	Absence Seizures	DRD2 HTR1A HTR1B SSTR2	2.62e-04	102	89	4	C4316903
Disease	Convulsions	DRD2 HTR1A HTR1B SSTR2	2.62e-04	102	89	4	C4048158
Disease	Seizures, Focal	DRD2 HTR1A HTR1B SSTR2	2.82e-04	104	89	4	C0751495
Disease	Myoclonic Seizures	DRD2 HTR1A HTR1B SSTR2	2.82e-04	104	89	4	C4317123
Disease	Tonic - clonic seizures	DRD2 HTR1A HTR1B SSTR2	2.82e-04	104	89	4	C0494475
Disease	Memory Loss	DRD2 HTR1A CHD1	3.00e-04	43	89	3	C0751295
Disease	Age-Related Memory Disorders	DRD2 HTR1A CHD1	3.00e-04	43	89	3	C0751292
Disease	Memory Disorder, Spatial	DRD2 HTR1A CHD1	3.00e-04	43	89	3	C0751294
Disease	Memory Disorder, Semantic	DRD2 HTR1A CHD1	3.00e-04	43	89	3	C0751293
Disease	Memory Disorders	DRD2 HTR1A CHD1	3.00e-04	43	89	3	C0025261
Disease	FEV/FEC ratio	STRBP SRGAP2 CHRM3 DENND2B DLC1 MYL9 PTPRM CTCF SRGAP3 MYO15A ARHGAP20 PCDH10	3.15e-04	1228	89	12	EFO_0004713
Disease	Major depression, single episode	DRD2 HTR1A	3.19e-04	9	89	2	C0024517
Disease	Memory impairment	DRD2 HTR1A CHD1	3.21e-04	44	89	3	C0233794
Disease	Intellectual Disability	AHI1 MAP7D3 ASH1L CTCF SRGAP3 ARL13B NKAP	4.14e-04	447	89	7	C3714756
Disease	Cocaine-Related Disorders	DRD2 HTR1A HTR1B RPS6KA5	4.42e-04	117	89	4	C0236736
Disease	body mass index, osteoarthritis	DRD2 CWC27 PTPRM	5.89e-04	54	89	3	EFO_0004340, MONDO_0005178
Disease	Cocaine Abuse	DRD2 HTR1A HTR1B RPS6KA5	6.02e-04	127	89	4	C0009171
Disease	Cocaine Dependence	DRD2 HTR1A HTR1B RPS6KA5	8.44e-04	139	89	4	C0600427
Disease	depressive disorder (is_implicated_in)	DRD2 HTR1A	1.19e-03	17	89	2	DOID:1596 (is_implicated_in)
Disease	cyclic adenosine monophosphate measurement	MAST4 PTPRM	1.19e-03	17	89	2	EFO_0010473
Disease	CCL4 measurement	TBC1D3 TBC1D3F	1.65e-03	20	89	2	EFO_0004751
Disease	Familial aplasia of the vermis	AHI1 ARL13B	1.65e-03	20	89	2	cv:C0431399
Disease	Joubert syndrome 1	AHI1 ARL13B	1.82e-03	21	89	2	C4551568
Disease	anxiety disorder (implicated_via_orthology)	HTR1A HTR1B	2.00e-03	22	89	2	DOID:2030 (implicated_via_orthology)
Disease	hippocampal sclerosis of aging	CUEDC1 NPIPB13	2.18e-03	23	89	2	EFO_0005678
Disease	Anhedonia	DRD2 HTR1A	2.38e-03	24	89	2	C0178417
Disease	Bradycardia	DRD2 HTR1A	2.79e-03	26	89	2	C0428977

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKREQSKKKRKTMTS	DDX52	81	Q9Y2R4
KKKLMAARERKATKT	HTR1B	301	P28222
TIIRKINKMKTLKRK	ASH1L	981	Q9NR48
MRERIAKKLKKDTSA	CWC27	281	Q6UX04
TKKSKRGRKRKMRSK	CTCF	591	P49711
LMREKKKLKKKLVRS	AHI1	26	Q8N157
TKRKRMSLVKEKKAA	CHRM3	476	P20309
VRKLEKMTKRKKTIN	ANKRD30A	51	Q9BXX3
KASENRKKRRVHKKM	EAPP	221	Q56P03
KKTKKLRMKRNHRVE	ARL13B	346	Q3SXY8
SRRKVKMVEFLLKKK	ANKRD36B	161	Q8N2N9
AKRGKKRLKKLSMSS	DENND2B	626	P78524
SRTTMQKRLKKEKKT	DACH2	511	Q96NX9
RRKARAKKNKAMKSI	CHD1	1331	O14646
RRAIRDAKTPDKMKK	IQGAP1	1426	P46940
TKVRAKIRKRKVTTK	NPIPB3	151	Q92617
RTVKMKQRDKKVVTK	HPF1	206	Q9NWY4
KVRAKIRKMKVTTKV	NPIPA1	116	Q9UND3
TKVRAKIRKRKVTTK	NPIPB12	151	F8W0I5
RMVLRKLSKKDVTTK	LTN1	66	O94822
KRKRKARTVLKSTSK	MYO15A	71	Q9UKN7
RSKWKRKMRAEKRKK	LLPH	6	Q9BRT6
MSSKRAKAKTTKKRP	MYL9	1	P24844
KTSKRKTKISRKTRN	PIK3C2A	1606	O00443
IALSHRKTMKKRNKK	PDZD4	721	Q76G19
FSEKTKMRKSKRKHL	CUEDC1	326	Q9NWM3
RRLKKGKKSKRSMND	SELL	356	P14151
TKVRAKIRKRKVTTK	NPIPB5	151	A8MRT5
DKAPLAKRRKMKKTS	RPS6KA5	736	O75582
TKVRAKIRKRKVTTK	NPIPB7	151	O75200
RARKKKLSKSDIMLV	PCDH10	776	Q9P2E7
LLSKRKKVKMKREKA	HECTD4	2886	Q9Y4D8
TKVRAKIRKRKVTTK	NPIPB4	151	C9JG80
FALRRKKKKTIKMLM	GPR83	281	Q9NYM4
TKVRAKIRKRKVTTK	NPIPB15	151	A6NHN6
RKMKRKESAFKSMLK	PRPF40A	741	O75400
TKVRAKIRKRKVTTK	NPIPB11	151	E5RHQ5
AKAEEKKRRKMSKGL	CACNA1S	676	Q13698
KKRTSFKRKASKRGM	DGKI	341	O75912
RSMKQISKEKLKARR	DHX57	751	Q6P158
AKRKMALARERKTVK	HTR1A	331	P08908
SRIKMAQKLAKSRKK	APBA1	491	Q02410
RKKRIEEIMKRTRKT	MAP7D3	711	Q8IWC1
RMVRRSKKSKKKESL	MAST4	1246	O15021
KTAAKMEKKVSKRSR	KLHDC4	16	Q8TBB5
KTMSRRKLSQQKEKK	DRD2	356	P14416
RLEKKRIKKRKGESM	GRK5	216	P34947
TKVRAKIRKRKVTTK	NPIPB9	166	F8W1W9
SSRSKERSKKRRKKK	NKAP	186	Q8N5F7
TKVRAKIRKRKVTTK	NPIPB13	151	A6NJU9
KRKLAKKRKETMSST	PTPRM	766	P28827
KVRAKIRKMKVTTKV	NPIPA7	116	E9PJI5
KVRAKIRKMKVTTKV	NPIPA8	116	P0DM63
SCTKKKMKTLAERRR	ARHGAP20	31	Q9P2F6
KSPRTVRKLSMKMKK	SYDE2	521	Q5VT97
RPRRKTKTLMKKDKY	SOX2	111	P48431
RRSSVKKIEKMKEKR	SRGAP1	211	Q7Z6B7
SKRKSKDKKRKRSRS	SRRM2	236	Q9UQ35
VKRKKVVHMNKLRKT	RNF151	61	Q2KHN1
KVKRSKKRRKEASSS	NKTR	231	P30414
KVRAKIRKMKVTTKV	NPIPA5	116	E9PKD4
KVAEAKARKKRRMLK	FTSJ3	741	Q8IY81
MKEKSKNAAKTRREK	SIM2	1	Q14190
KTKKLRTARRQKTKM	SPATA16	546	Q9BXB7
KKMKRNLRKILDSKA	STRBP	371	Q96SI9
RRSSVKKIEKMKEKH	SRGAP2C	221	P0DJJ0
RRSSVKKIEKMKEKR	SRGAP2B	221	P0DMP2
MKKVKKKRSEARRHR	SPATA3	1	Q8NHX4
MKSLKKKHRSPERRK	SLF2	161	Q8IX21
KSKTRSLLKRMESLK	DLC1	661	Q96QB1
KRKKSEKKVTRMVSI	SSTR2	246	P30874
KTLKEECKRRKKMIS	DZIP1	171	Q86YF9
AKAKSRIKMKKARKI	BRPF1	486	P55201
RIKMKKARKILAEKR	BRPF1	491	P55201
KVKSKRRLEKEERKM	CLSPN	166	Q9HAW4
ASCMKKKRSRSSKKR	TRAM1L1	331	Q8N609
QKKIVSKKMSTDRKR	ZNF540	141	Q8NDQ6
SRIKRKKQEMKKRKT	TSPYL2	401	Q9H2G4
VKAKMLTKDRRLSKK	TRPM6	1571	Q9BX84
DGTLKSRKRRKMSKK	REV3L	956	O60673
RRSSVKKIEKMKEKR	SRGAP3	211	O43295
KHLRASMKKLTRKKG	TBC1D3F	341	A6NER0
RKSKRHSSSKRRKSM	SAGE1	51	Q9NXZ1
GKAKLRSMKERKLEK	WASH2P	376	Q6VEQ5
KTSRKQRKERKNRMK	RPS24	101	P62847
RRSSVKKIEKMKEKR	SRGAP2	221	O75044
KKKKSTRKKRRRSSS	SRRM4	111	A7MD48
GKAKLRSMKERKLEK	WASHC1	376	A8K0Z3
AKLRSMKERKLEKKQ	WASH3P	376	C4AMC7
KHLRASMKKLTRKKG	TBC1D3E	341	A0A087X179
KKRERKTSSKSSVRK	PLEC	4261	Q15149
KATRTKRRRKEKMEA	nan	21	Q1RN00
MVTFKKTKRRVKKIR	SART1	396	O43290
KMKKRVKDELRKLNT	ZNFX1	896	Q9P2E3
GLEKKRKRKMDVSKI	ZNF644	286	Q9H582
RLRESKKKAKMASAT	UHRF1	376	Q96T88
KKRMKSKRSRSRESS	TOPORS	621	Q9NS56
MKFRKEDSSKRIRKS	ERCC4	451	Q92889
EKTRALMALKKRTKD	TCIM	76	Q9NR00
KHLRASMKKLTRKKG	TBC1D3	341	Q8IZP1
KHLRASMKKLTRKKG	TBC1D3K	341	A0A087X1G2
KKMSSKGLSGKKRRR	TNRC6A	1171	Q8NDV7
KHLRASMKKLTRKKG	TBC1D3C	341	Q6IPX1
KGMKKKSRAERKTEI	VWA5B1	311	Q5TIE3
KERRVLLVMSKAKRK	ZC3H7B	726	Q9UGR2
KQSRSEKKARKAMSK	NACA	1931	E9PAV3
KAKQSRSEKKARKAM	NACA	66	Q13765
PKKRKMTKARLERSK	NEUROD2	106	Q15784