Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 ZNF722 ZNF735 ZNF197 ZNF790 ZNF189 ZNF66 ZNF485 ZNF766 ZNF80 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	7.77e-24	1459	83	40	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF728 ZNF722 ZNF735 ZNF197 ZNF790 ZNF189 ZNF66 ZNF485 ZNF766 ZNF80 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	2.82e-23	1412	83	39	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF729 ZNF597 ZNF93 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 ZNF722 ZNF735 ZNF197 ZNF790 ZNF189 ZNF66 ZNF485 ZNF766 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	5.83e-22	1244	83	36	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF729 ZNF597 ZNF93 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 ZNF722 ZNF735 ZNF197 ZNF790 ZNF189 ZNF66 ZNF485 ZNF766 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	1.19e-21	1271	83	36	GO:0000987
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF729 ZNF597 ZNF695 VEZF1 ZNF197 ZNF485 ZNF226 ZNF227 ZNF519 ZNF107 ZNF726 ZNF433 ZNF786 ZNF445	7.08e-08	560	83	14	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF729 ZNF597 ZNF695 VEZF1 ZNF197 ZNF485 ZNF226 ZNF227 ZNF519 ZNF107 ZNF726 ZNF433 ZNF786 ZNF445	8.07e-08	566	83	14	GO:0001216
GeneOntologyBiologicalProcess	transposable element silencing	ZNF729 ZNF93 TUT7 ZNF107 ZNF726	1.06e-06	46	82	5	GO:0010526
GeneOntologyBiologicalProcess	retrotransposition	ZNF729 ZNF93 TUT7 ZNF107 ZNF726	1.31e-06	48	82	5	GO:0032197
GeneOntologyBiologicalProcess	transposition	ZNF729 ZNF93 TUT7 ZNF107 ZNF726	1.62e-06	50	82	5	GO:0032196
GeneOntologyBiologicalProcess	skeletal muscle satellite cell migration	RHOA RHOC	1.56e-05	2	82	2	GO:1902766
GeneOntologyBiologicalProcess	negative regulation of gene expression via chromosomal CpG island methylation	ZNF93 ZNF726 ZNF445	1.01e-04	23	82	3	GO:0044027
Domain	ZINC_FINGER_C2H2_1	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 TUT7 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF654 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	1.95e-35	777	80	41	PS00028
Domain	-	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF366 ZNF728 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF654 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	6.46e-35	679	80	39	3.30.160.60
Domain	Znf_C2H2	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 TUT7 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF654 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	8.16e-35	805	80	41	IPR007087
Domain	zf-C2H2	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	1.42e-34	693	80	39	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF366 ZNF728 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF654 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	1.50e-34	694	80	39	IPR013087
Domain	KRAB	ZNF729 ZNF597 ZNF93 ZNF627 ZNF716 ZNF562 ZNF695 ZNF354A ZNF789 ZNF607 ZNF732 ZNF728 ZNF862 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	2.62e-34	358	80	32	PS50805
Domain	KRAB	ZNF729 ZNF597 ZNF93 ZNF627 ZNF716 ZNF562 ZNF695 ZNF354A ZNF789 ZNF607 ZNF732 ZNF728 ZNF862 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	2.62e-34	358	80	32	PF01352
Domain	ZINC_FINGER_C2H2_2	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF654 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	4.39e-34	775	80	40	PS50157
Domain	KRAB	ZNF729 ZNF597 ZNF93 ZNF627 ZNF716 ZNF562 ZNF695 ZNF354A ZNF789 ZNF607 ZNF732 ZNF728 ZNF862 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	7.00e-34	369	80	32	SM00349
Domain	KRAB	ZNF729 ZNF597 ZNF93 ZNF627 ZNF716 ZNF562 ZNF695 ZNF354A ZNF789 ZNF607 ZNF732 ZNF728 ZNF862 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	7.64e-34	370	80	32	IPR001909
Domain	ZnF_C2H2	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF654 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	2.26e-33	808	80	40	SM00355
Domain	Znf_C2H2-like	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF366 ZNF728 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF654 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	2.90e-32	796	80	39	IPR015880
Domain	zf-C2H2_6	ZNF729 ZNF597 ZNF93 ZNF627 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 ZNF607 ZNF732 ZNF366 ZNF728 ZNF735 ZNF197 ZNF790 ZNF766 ZNF80 ZNF227 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF433 ZNF284 ZNF445	8.21e-30	314	80	28	PF13912
Domain	RHO	RHOA RHOB RHOC RND2	1.44e-06	20	80	4	PS51420
Domain	KRAB_dom_C2H2_Znf_fam	ZNF862 KIAA1586	1.80e-04	5	80	2	IPR026613
Domain	zf-C2H2_11	ZNF354A ZNF354B	6.40e-04	9	80	2	PF16622
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	ZNF729 ZNF597 ZNF627 ZNF138 ZNF716 ZNF562 ZNF354A ZNF607 ZNF732 ZNF678 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF304 ZNF445	4.69e-12	1387	62	27	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	ZNF729 ZNF93 ZNF695 ZNF354A ZNF189 ZNF226 ZNF519 ZNF317 ZNF107 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF445	1.33e-07	768	62	16	MM14851
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	RHOA RHOB RHOC	8.05e-07	5	62	3	MM15221
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_CIT	RHOA RHOB RHOC	2.80e-06	7	62	3	MM15217
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ZNF93 ZNF354A ZNF317 ZNF726 ZNF433	4.49e-06	56	62	5	MM17236
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	ZNF729 ZNF93 ZNF695 ZNF354A ZNF189 ZNF226 ZNF519 ZNF317 ZNF107 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF445	5.90e-06	1022	62	16	MM15436
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_RHOTEKIN_AND_RHOPHILINS	RHOA RHOB RHOC	6.68e-06	9	62	3	M27551
Pathway	PID_P75_NTR_PATHWAY	RHOA RHOB RHOC TRAF6 PIK3CA	1.18e-05	68	62	5	M153
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	RHOA RHOB RHOC	1.30e-05	11	62	3	MM15046
Pathway	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	RHOA RHOB PIK3CA VAV3	1.60e-05	35	62	4	MM14512
Pathway	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	RHOA RHOB PIK3CA VAV3	1.60e-05	35	62	4	M773
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	RHOA RHOB RHOC	3.55e-05	15	62	3	MM15037
Pathway	PID_EPHA2_FWD_PATHWAY	RHOA PIK3CA VAV3	7.47e-05	19	62	3	M273
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_ROCKS	RHOA RHOB RHOC	7.47e-05	19	62	3	M27493
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_CIT	RHOA RHOB RHOC	7.47e-05	19	62	3	M27489
Pathway	REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE	RHOA RHOB RHOC	8.76e-05	20	62	3	M18415
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_PKNS	RHOA RHOB RHOC	1.35e-04	23	62	3	MM15216
Pathway	REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING	RHOA RHOB RHOC	1.54e-04	24	62	3	M2243
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	RHOA RHOB RHOC SEMA6A	1.77e-04	64	62	4	M7923
Pathway	PID_AVB3_INTEGRIN_PATHWAY	RHOA COL4A5 PIK3CA VAV3	3.10e-04	74	62	4	M160
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	ZNF93 ZNF354A ZNF317 ZNF726 ZNF433	3.23e-04	136	62	5	MM14848
Pathway	PID_AVB3_OPN_PATHWAY	RHOA PIK3CA VAV3	3.34e-04	31	62	3	M63
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	RHOA RHOB RHOC VAV3	3.61e-04	77	62	4	MM15044
Pathway	BIOCARTA_CDC42RAC_PATHWAY	RHOA PIK3CA	3.94e-04	7	62	2	MM1487
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	RHOA RHOB RHOC VAV3	4.18e-04	80	62	4	M800
Pathway	BIOCARTA_CDC42RAC_PATHWAY	RHOA PIK3CA	5.24e-04	8	62	2	M5291
Pathway	REACTOME_PI3K_AKT_ACTIVATION	RHOA PIK3CA	5.24e-04	8	62	2	MM14776
Pathway	REACTOME_RHO_GTPASE_CYCLE	RHOA RHOB RHOC CCP110 PIK3CA VAV3 RND2 ARHGAP11A	6.42e-04	439	62	8	MM15595
Pathway	REACTOME_PI3K_AKT_ACTIVATION	RHOA PIK3CA	6.72e-04	9	62	2	M714
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	COL4A5 TRAF6 PIK3CA WNT10B WNT9A	6.99e-04	161	62	5	M39770
Pathway	REACTOME_RHO_GTPASE_CYCLE	RHOA RHOB RHOC CCP110 PIK3CA VAV3 RND2 ARHGAP11A	7.55e-04	450	62	8	M27078
Pathway	PID_THROMBIN_PAR1_PATHWAY	RHOA PIK3CA PRKCD	8.82e-04	43	62	3	M238
Pathway	WP_FIBRIN_COMPLEMENT_RECEPTOR_3_SIGNALING	RHOA TRAF6 PIK3CA	8.82e-04	43	62	3	M39744
Pathway	REACTOME_SIGNALING_BY_ERBB2	RHOA PIK3CA PRKCD	9.44e-04	44	62	3	MM14520
Pathway	PID_CXCR4_PATHWAY	RHOA RHOB RHOC PIK3CA	9.70e-04	100	62	4	M124
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	RHOA RHOB RHOC COL4A5 PIK3CA VAV3	9.82e-04	261	62	6	MM15676
Pathway	REACTOME_SIGNALING_BY_VEGF	RHOA PIK3CA PRKCD VAV3	1.08e-03	103	62	4	MM14752
Pathway	REACTOME_SIGNALING_BY_VEGF	RHOA PIK3CA PRKCD VAV3	1.21e-03	106	62	4	M27077
Pathway	WP_FIBRIN_COMPLEMENT_RECEPTOR_3_SIGNALING_PATHWAY	RHOA TRAF6 PIK3CA	1.22e-03	48	62	3	MM15897
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS_BY_KRAB_ZFP_PROTEINS	ZNF93 ZNF354A ZNF519 ZNF317	1.25e-03	107	62	4	M48260
Pathway	WP_SPINAL_CORD_INJURY	RHOA RHOB RHOC SEMA6A	1.29e-03	108	62	4	MM15954
Pathway	REACTOME_SIGNALING_BY_ERBB2	RHOA PIK3CA PRKCD	1.37e-03	50	62	3	M553
Pathway	REACTOME_SEMAPHORIN_INTERACTIONS	RHOA RHOB RHOC	1.45e-03	51	62	3	MM14967
Pathway	WP_GASTRIN_SIGNALING	RHOA RHOB PIK3CA PRKCD	1.63e-03	115	62	4	M39866
Pathway	WP_SPINAL_CORD_INJURY	RHOA RHOB RHOC SEMA6A	1.74e-03	117	62	4	M39341
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	PIK3CA WNT10B WNT9A PRKCD	1.79e-03	118	62	4	M39852
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	RHOA RHOB RHOC CCP110 PIK3CA PRKCD VAV3 RND2 ARHGAP11A	2.00e-03	649	62	9	MM15690
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF93 ZNF627 ZNF562 ZNF354A ZNF789 ZNF607 ZNF678 ZNF728 ZNF197 ZNF485 ZNF766 ZNF227 ZNF317 ZNF107 ZNF354B ZNF726 ZNF445	1.06e-22	181	83	17	37372979
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF729 ZNF93 ZNF716 ZNF695 ZNF107 ZNF726	6.99e-11	29	83	6	14563677
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	ZNF729 ZNF695 ZNF317 ZNF107 ZNF726 ZNF445	1.98e-09	49	83	6	9630514
Pubmed	RhoA, RhoB and RhoC have different roles in cancer cell migration.	RHOA RHOB RHOC	1.31e-08	3	83	3	23488932
Pubmed	Divergence of Rho residue 43 impacts GEF activity.	RHOA RHOB RHOC	1.31e-08	3	83	3	22673745
Pubmed	A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.	RHOA RHOB RHOC	1.31e-08	3	83	3	12939257
Pubmed	The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells.	RHOA RHOB RHOC	1.31e-08	3	83	3	26741994
Pubmed	Transcriptional and post-transcriptional regulation of the genes encoding the small GTPases RhoA, RhoB, and RhoC: implications for the pathogenesis of human diseases.	RHOA RHOB RHOC	1.31e-08	3	83	3	29500478
Pubmed	RhoA, RhoB and RhoC differentially regulate endothelial barrier function.	RHOA RHOB RHOC	1.31e-08	3	83	3	28949796
Pubmed	Prenylation inhibitors stimulate both estrogen receptor alpha transcriptional activity through AF-1 and AF-2 and estrogen receptor beta transcriptional activity.	RHOA RHOB RHOC	1.31e-08	3	83	3	15642170
Pubmed	Spatiotemporal analysis of RhoA/B/C activation in primary human endothelial cells.	RHOA RHOB RHOC	1.31e-08	3	83	3	27147504
Pubmed	Rho isoforms have distinct and specific functions in the process of epithelial to mesenchymal transition in renal proximal tubular cells.	RHOA RHOB RHOC	1.31e-08	3	83	3	19477269
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF729 ZNF93 ZNF107 ZNF726	4.03e-08	15	83	4	15885501
Pubmed	Rhotekin, a new putative target for Rho bearing homology to a serine/threonine kinase, PKN, and rhophilin in the rho-binding domain.	RHOA RHOB RHOC	5.23e-08	4	83	3	8662891
Pubmed	Cooperation between mDia1 and ROCK in Rho-induced actin reorganization.	RHOA RHOB RHOC	5.23e-08	4	83	3	10559899
Pubmed	XPLN, a guanine nucleotide exchange factor for RhoA and RhoB, but not RhoC.	RHOA RHOB RHOC	5.23e-08	4	83	3	12221096
Pubmed	Rho isoform-specific interaction with IQGAP1 promotes breast cancer cell proliferation and migration.	RHOA RHOB RHOC	5.23e-08	4	83	3	22992742
Pubmed	The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.	RHOA RHOB RHOC	1.31e-07	5	83	3	8617235
Pubmed	Rho localization in cells and tissues.	RHOA RHOB RHOC	1.31e-07	5	83	3	15093731
Pubmed	A novel partner for the GTP-bound forms of rho and rac.	RHOA RHOB RHOC	1.31e-07	5	83	3	8543060
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF223 ZNF226 ZNF227 ZNF284	1.42e-07	20	83	4	12743021
Pubmed	Small GTP-binding proteins and the regulation of the actin cytoskeleton.	RHOA RHOB RHOC	2.61e-07	6	83	3	7888179
Pubmed	Rho GTPases and the actin cytoskeleton.	RHOA RHOB RHOC	2.61e-07	6	83	3	9438836
Pubmed	The bacterial virulence factor lymphostatin compromises intestinal epithelial barrier function by modulating rho GTPases.	RHOA RHOB RHOC	2.61e-07	6	83	3	19286565
Pubmed	RHO binding to FAM65A regulates Golgi reorientation during cell migration.	RHOA RHOB RHOC	4.56e-07	7	83	3	27807006
Pubmed	Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1.	RHOA RHOB RHOC	1.09e-06	9	83	3	15151987
Pubmed	Mutation of ARHGAP9 in patients with coronary spastic angina.	RHOA RHOB RHOC VAV3	2.09e-06	38	83	4	19911011
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF729 ZNF93 ZNF716 VEZF1 TUT7 ZNF790 ZNF236 ZNF726 ZNF654 ZNF786 ZNF445	3.51e-06	808	83	11	20412781
Pubmed	Kctd13 deletion reduces synaptic transmission via increased RhoA.	RHOA RHOB RHOC	3.68e-06	13	83	3	29088697
Pubmed	A high expression ratio of RhoA/RhoB is associated with the migratory and invasive properties of basal-like Breast Tumors.	RHOA RHOB	5.63e-06	2	83	2	33162807
Pubmed	RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts.	RHOA RHOC	5.63e-06	2	83	2	21454503
Pubmed	Activation of a bacterial virulence protein by the GTPase RhoA.	RHOA RHOC	5.63e-06	2	83	2	19887681
Pubmed	Coding sequence of human rho cDNAs clone 6 and clone 9.	RHOB RHOC	5.63e-06	2	83	2	3283705
Pubmed	Functional analysis of the promoters of the small GTPases RhoA and RhoB in embryonic stem cells.	RHOA RHOB	5.63e-06	2	83	2	28739254
Pubmed	A novel ras-related gene family.	RHOB RHOC	5.63e-06	2	83	2	3888408
Pubmed	Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB.	RHOA RHOB	5.63e-06	2	83	2	29059167
Pubmed	Up-regulation of small GTPases, RhoA and RhoC, is associated with tumor progression in ovarian carcinoma.	RHOA RHOC	5.63e-06	2	83	2	12808121
Pubmed	Chromosome localization of human ARH genes, a ras-related gene family.	RHOA RHOB	5.63e-06	2	83	2	2407642
Pubmed	Endothelial RhoB and RhoC are dispensable for leukocyte diapedesis and for maintaining vascular integrity during diapedesis.	RHOB RHOC	5.63e-06	2	83	2	28960175
Pubmed	GTPases Rho distribution in intraepithelial and invasive neoplasias of the uterine cervix.	RHOA RHOB	5.63e-06	2	83	2	24984542
Pubmed	ABCs of RhoGTPases indicating potential role as oncotargets.	RHOA RHOC	5.63e-06	2	83	2	28508825
Pubmed	Immunolocalization of RhoA and RhoB GTPases in pleomorphic adenoma of the parotid.	RHOA RHOB	5.63e-06	2	83	2	25454559
Pubmed	Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters.	RHOA RHOC	5.63e-06	2	83	2	19499974
Pubmed	Characterization of the roles of RHOC and RHOA GTPases in invasion, motility, and matrix adhesion in inflammatory and aggressive breast cancers.	RHOA RHOC	5.63e-06	2	83	2	20503409
Pubmed	TRAF6 interacts with and ubiquitinates PIK3CA to enhance PI3K activation.	TRAF6 PIK3CA	5.63e-06	2	83	2	29729098
Pubmed	Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins.	RHOA RHOC	5.63e-06	2	83	2	7989340
Pubmed	Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer.	RHOA RHOC	5.63e-06	2	83	2	33825439
Pubmed	RhoB controls coordination of adult angiogenesis and lymphangiogenesis following injury by regulating VEZF1-mediated transcription.	RHOB VEZF1	5.63e-06	2	83	2	24280686
Pubmed	Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.	RHOA RHOC	5.63e-06	2	83	2	20828398
Pubmed	Anti-RhoA and anti-RhoC siRNAs inhibit the proliferation and invasiveness of MDA-MB-231 breast cancer cells in vitro and in vivo.	RHOA RHOC	5.63e-06	2	83	2	15668138
Pubmed	Lipid rafts of primary endothelial cells are essential for Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8-induced phosphatidylinositol 3-kinase and RhoA-GTPases critical for microtubule dynamics and nuclear delivery of viral DNA but dispensable for binding and entry.	RHOA PIK3CA	5.63e-06	2	83	2	17507466
Pubmed	Differential requirement for RhoA GTPase depending on the cellular localization of protein kinase D.	RHOA PRKCD	5.63e-06	2	83	2	16772297
Pubmed	RhoA downstream of G(q) and G(12/13) pathways regulates protease-activated receptor-mediated dense granule release in platelets.	RHOA PRKCD	5.63e-06	2	83	2	19073150
Pubmed	Ovarian clear cell carcinomas: RHO GTPases may contribute to explain their singular biologic behavior.	RHOA RHOC	5.63e-06	2	83	2	21208644
Pubmed	Specific induction of migration and invasion of pancreatic carcinoma cells by RhoC, which differs from RhoA in its localisation and activity.	RHOA RHOC	5.63e-06	2	83	2	19642867
Pubmed	Clinical and prognostic significance of RhoA and RhoC gene expression in esophageal squamous cell carcinoma.	RHOA RHOC	5.63e-06	2	83	2	17896152
Pubmed	Leukotriene D(4) induces stress-fibre formation in intestinal epithelial cells via activation of RhoA and PKCdelta.	RHOA PRKCD	5.63e-06	2	83	2	12154081
Pubmed	Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2.	ZNF354A ZNF354B	5.63e-06	2	83	2	10564808
Pubmed	Sequence of rho small GTP-binding protein cDNAs from human retina and identification of novel 5' end cloning artifacts.	RHOA RHOC	5.63e-06	2	83	2	7835413
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	ZNF729 ZNF93 ZNF138 ZNF716 ZNF766 ZNF236 ZNF107 ZNF726	1.27e-05	451	83	8	36168627
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF93 ZNF317 ZNF726	1.45e-05	20	83	3	7479878
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF93 ZNF317 ZNF726	1.45e-05	20	83	3	2542606
Pubmed	CSN5 inhibition triggers inflammatory signaling and Rho/ROCK-dependent loss of endothelial integrity.	RHOA RHOB	1.69e-05	3	83	2	31148579
Pubmed	RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness.	RHOA RHOB	1.69e-05	3	83	2	24782506
Pubmed	Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers.	RHOA ARHGAP11A	1.69e-05	3	83	2	27216196
Pubmed	RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha.	RHOA RHOB	1.69e-05	3	83	2	18524772
Pubmed	Targeted disruption of protein kinase C epsilon reduces cell invasion and motility through inactivation of RhoA and RhoC GTPases in head and neck squamous cell carcinoma.	RHOA RHOC	1.69e-05	3	83	2	17018591
Pubmed	RhoA and RhoC differentially modulate estrogen receptor α recruitment, transcriptional activities, and expression in breast cancer cells (MCF-7).	RHOA RHOC	1.69e-05	3	83	2	24096540
Pubmed	Structural and mechanistic insights into the interaction between Rho and mammalian Dia.	RHOA RHOC	1.69e-05	3	83	2	15864301
Pubmed	Myosin-interacting guanine exchange factor (MyoGEF) regulates the invasion activity of MDA-MB-231 breast cancer cells through activation of RhoA and RhoC.	RHOA RHOC	1.69e-05	3	83	2	19421144
Pubmed	Pragmin, a novel effector of Rnd2 GTPase, stimulates RhoA activity.	RHOA RND2	1.69e-05	3	83	2	16481321
Pubmed	Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells.	RHOA RHOB	1.69e-05	3	83	2	18694745
Pubmed	Down expression of LRP1B promotes cell migration via RhoA/Cdc42 pathway and actin cytoskeleton remodeling in renal cell cancer.	RHOA LRP1B	1.69e-05	3	83	2	23521319
Pubmed	SmgGDS is a guanine nucleotide exchange factor that specifically activates RhoA and RhoC.	RHOA RHOC	1.69e-05	3	83	2	21242305
Pubmed	A p27(kip1)-binding protein, p27RF-Rho, promotes cancer metastasis via activation of RhoA and RhoC.	RHOA RHOC	1.69e-05	3	83	2	21087931
Pubmed	RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication.	RHOA RHOC	1.69e-05	3	83	2	20697357
Pubmed	Syndecan-2 regulation of morphology in breast carcinoma cells is dependent on RhoGTPases.	RHOA RHOC	1.69e-05	3	83	2	24447566
Pubmed	Consequences of mevalonate depletion. Differential transcriptional, translational, and post-translational up-regulation of Ras, Rap1a, RhoA, AND RhoB.	RHOA RHOB	1.69e-05	3	83	2	11788600
Pubmed	RhoB, not RhoA, represses the transcription of the transforming growth factor beta type II receptor by a mechanism involving activator protein 1.	RHOA RHOB	1.69e-05	3	83	2	11741970
Pubmed	Overexpression of Pin1 and rho signaling partners correlates with metastatic behavior and poor recurrence-free survival of hepatocellular carcinoma patients.	RHOA RHOC	1.69e-05	3	83	2	31324164
Pubmed	Urokinase plasminogen activator inhibits HIV virion release from macrophage-differentiated chronically infected cells via activation of RhoA and PKCε.	RHOA PRKCD	1.69e-05	3	83	2	21858203
Pubmed	The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.	RHOA RHOC	1.69e-05	3	83	2	8816443
Pubmed	SWAP-70 regulates RhoA/RhoB-dependent MHCII surface localization in dendritic cells.	RHOA RHOB	1.69e-05	3	83	2	18802007
Pubmed	RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis.	RHOA RHOC	1.69e-05	3	83	2	21757538
Pubmed	RhoA/C inhibits proliferation by inducing the synthesis of GPRC5A.	RHOA RHOC	1.69e-05	3	83	2	32719397
Pubmed	Selective expression of the small GTPase RhoB in the early developing mouse lens.	RHOA RHOB	1.69e-05	3	83	2	11747086
Pubmed	Modulation of Both Intrinsic and Extrinsic Factors Additively Promotes Rewiring of Corticospinal Circuits after Spinal Cord Injury.	RHOA RHOC	1.69e-05	3	83	2	34759029
Pubmed	RhoA and RhoC are involved in stromal cell-derived factor-1-induced cell migration by regulating F-actin redistribution and assembly.	RHOA RHOC	1.69e-05	3	83	2	28536953
Pubmed	[PI3-kinase mediates activity of RhoA and interaction of RhoA with mDia1 in thrombin-induced platelet aggregation].	RHOA PIK3CA	1.69e-05	3	83	2	20030946
Pubmed	AKAP-Lbc anchors protein kinase A and nucleates Galpha 12-selective Rho-mediated stress fiber formation.	RHOB RHOC	3.37e-05	4	83	2	11546812
Pubmed	Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice.	RHOA RHOC	3.37e-05	4	83	2	26030593
Pubmed	Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding.	RHOA RHOB	3.37e-05	4	83	2	11149925
Pubmed	Role of growth arrest and DNA damage-inducible α in Akt phosphorylation and ubiquitination after mechanical stress-induced vascular injury.	TRAF6 PIK3CA	3.37e-05	4	83	2	21816939
Pubmed	Rho GTPase independent regulation of ATM activation and cell survival by the RhoGEF Net1A.	RHOA RHOB	3.37e-05	4	83	2	25486363
Pubmed	Physical and functional interactions between protein tyrosine phosphatase alpha, PI 3-kinase, and PKCdelta.	PIK3CA PRKCD	3.37e-05	4	83	2	11676480
Pubmed	Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway.	RHOA RHOC	3.37e-05	4	83	2	20460433
Pubmed	The Rho target PRK2 regulates apical junction formation in human bronchial epithelial cells.	RHOA RHOC	3.37e-05	4	83	2	20974804
Pubmed	Immunohistochemical expression of Rho GTPases in ameloblastomas.	RHOA RHOB	3.37e-05	4	83	2	22092654
Pubmed	KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks.	ZNF732 ZNF735	3.37e-05	4	83	2	28273063
Pubmed	Mouse macrophages completely lacking Rho subfamily GTPases (RhoA, RhoB, and RhoC) have severe lamellipodial retraction defects, but robust chemotactic navigation and altered motility.	RHOA RHOB	3.37e-05	4	83	2	25213860
Interaction	TRIM28 interactions	ZNF93 ZNF627 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF728 ZNF197 ZNF485 ZNF766 ZNF223 ZNF226 ZNF227 ZNF317 ZNF107 ZNF354B ZNF726 ZNF284 ZNF304 ZNF445	2.38e-09	1474	82	24	int:TRIM28
Interaction	NOTCH2 interactions	RHOA RHOB RHOC ZNF627 VEZF1 WNT10B ZNF189 ZNF766 RND2 SMOC1 ZNF317 ZNF107 ZNF445	1.53e-08	423	82	13	int:NOTCH2
Interaction	SLITRK4 interactions	RHOA RHOB RHOC RND2	3.55e-06	26	82	4	int:SLITRK4
Interaction	FLRT2 interactions	RHOA RHOB RHOC RND2	5.60e-06	29	82	4	int:FLRT2
Interaction	OLR1 interactions	RHOA RHOB RHOC RND2	5.60e-06	29	82	4	int:OLR1
Interaction	ATP11A interactions	RHOA RHOB RHOC RND2	1.21e-05	35	82	4	int:ATP11A
Interaction	IL6ST interactions	RHOA RHOB RHOC TMPRSS13 PRKCD	1.27e-05	74	82	5	int:IL6ST
Interaction	PCDH17 interactions	RHOA RHOB RHOC RND2	1.36e-05	36	82	4	int:PCDH17
Interaction	TENM2 interactions	RHOA RHOB RHOC	1.39e-05	12	82	3	int:TENM2
Interaction	MUC13 interactions	RHOA RHOB RHOC RND2	1.52e-05	37	82	4	int:MUC13
Interaction	BLTP1 interactions	RHOA RHOB RHOC RND2	4.69e-05	49	82	4	int:BLTP1
Interaction	ZNF716 interactions	ZNF716 ZNF726	4.89e-05	3	82	2	int:ZNF716
Interaction	CRIM1 interactions	RHOA RHOB RHOC	8.19e-05	21	82	3	int:CRIM1
Interaction	SLITRK5 interactions	RHOA RHOB RHOC RND2	9.77e-05	59	82	4	int:SLITRK5
Interaction	LRP10 interactions	RHOA RHOB RHOC TMPRSS13 RND2	1.07e-04	115	82	5	int:LRP10
Interaction	ITIH1 interactions	PIK3CA MATN2 PHF11	1.24e-04	24	82	3	int:ITIH1
Interaction	ARHGAP5 interactions	RHOA RHOB RHOC RND2	1.26e-04	63	82	4	int:ARHGAP5
Interaction	GLI4 interactions	ZNF189 ZNF317 ZNF107 LRP1B ZNF445	1.58e-04	125	82	5	int:GLI4
Interaction	ITGA5 interactions	RHOA RHOB RHOC TMPRSS13 RND2	1.70e-04	127	82	5	int:ITGA5
Interaction	SLC20A2 interactions	RHOA RHOB RHOC RND2	1.70e-04	68	82	4	int:SLC20A2
Interaction	RAB32 interactions	RHOA RHOB RHOC RND2	1.70e-04	68	82	4	int:RAB32
Interaction	STX16 interactions	RHOA RHOB RHOC RND2	1.80e-04	69	82	4	int:STX16
Interaction	ANKRD26 interactions	RHOA RHOB RHOC ZNF607 RND2	1.96e-04	131	82	5	int:ANKRD26
Interaction	LDB3 interactions	RHOA PRKCD KLHL41	2.20e-04	29	82	3	int:LDB3
Interaction	SOWAHC interactions	RHOA RHOB RHOC	2.20e-04	29	82	3	int:SOWAHC
Interaction	TMEM185B interactions	RHOA RHOC	2.43e-04	6	82	2	int:TMEM185B
Interaction	RELL1 interactions	RHOA RHOB RHOC RND2	2.61e-04	76	82	4	int:RELL1
Interaction	DCBLD1 interactions	RHOA RHOB RHOC	2.69e-04	31	82	3	int:DCBLD1
Interaction	NECTIN3 interactions	RHOA RHOB RHOC RND2	2.89e-04	78	82	4	int:NECTIN3
Interaction	SLC16A7 interactions	RHOA RHOB RHOC	2.96e-04	32	82	3	int:SLC16A7
Interaction	PLCB4 interactions	RHOA RHOB RHOC	2.96e-04	32	82	3	int:PLCB4
Interaction	ZBTB47 interactions	ZCCHC9 TUT7 ZNF189 ZNF317 ZNF445	3.05e-04	144	82	5	int:ZBTB47
Interaction	CBARP interactions	RHOA RHOB RHOC RND2	3.18e-04	80	82	4	int:CBARP
Interaction	EPHB4 interactions	RHOA RHOB RHOC TMPRSS13 RND2	3.25e-04	146	82	5	int:EPHB4
Interaction	SLC7A11 interactions	RHOA RHOB RHOC RND2	3.50e-04	82	82	4	int:SLC7A11
Interaction	STK11IP interactions	RHOA RHOB RHOC RND2	3.66e-04	83	82	4	int:STK11IP
Interaction	LTBP2 interactions	ZNF627 ZNF607 ZNF766 ZNF107	4.01e-04	85	82	4	int:LTBP2
Interaction	PTPRS interactions	RHOA RHOB RHOC TMPRSS13 RND2	4.03e-04	153	82	5	int:PTPRS
Interaction	ADGRG6 interactions	RHOA RHOB RHOC	4.21e-04	36	82	3	int:ADGRG6
Interaction	PRKCD interactions	RHOA RHOB RHOC TRAF6 PIK3CA PRKCD	4.22e-04	238	82	6	int:PRKCD
Interaction	IFNGR1 interactions	RHOA RHOB RHOC RND2	4.58e-04	88	82	4	int:IFNGR1
Interaction	FAM171A1 interactions	RHOA RHOB RHOC RND2	4.78e-04	89	82	4	int:FAM171A1
Interaction	NECTIN2 interactions	RHOA RHOB RHOC TMPRSS13 RND2	4.80e-04	159	82	5	int:NECTIN2
Interaction	TNFRSF10B interactions	RHOA RHOB RHOC PRKCD RND2	4.94e-04	160	82	5	int:TNFRSF10B
Interaction	SLC11A2 interactions	RHOA RHOB RHOC	4.94e-04	38	82	3	int:SLC11A2
Interaction	SUN1 interactions	RHOA RHOB RHOC TMPRSS13 RND2	5.08e-04	161	82	5	int:SUN1
Interaction	C2CD5 interactions	RHOA RHOB DUSP5 RND2	6.12e-04	95	82	4	int:C2CD5
Interaction	ROBO1 interactions	RHOA RHOB RHOC RND2	6.36e-04	96	82	4	int:ROBO1
Cytoband	19p12	ZNF729 ZNF93 ZNF728 ZNF66 ZNF726	6.66e-07	90	83	5	19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF729 ZNF93 ZNF728 ZNF66 ZNF726	3.00e-06	122	83	5	chr19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	ZNF138 ZNF117 ZNF722 ZNF735 ZNF107	1.38e-04	271	83	5	chr7q11
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	RHOA ZNF197 PRKCD FYCO1 ZNF445	2.80e-04	316	83	5	chr3p21
Cytoband	5q23.3	ADAMTS19 SLC27A6	2.90e-04	14	83	2	5q23.3
Cytoband	7q11.21	ZNF138 ZNF117 ZNF735	4.72e-04	83	83	3	7q11.21
Cytoband	19p13.2	ZNF627 ZNF562 ZNF442 ZNF433	8.14e-04	229	83	4	19p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr5q23	ADAMTS19 SLC27A6 SEMA6A	1.28e-03	117	83	3	chr5q23
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF607 ZNF790 ZNF766 ZNF223 ZNF226 ZNF227 ZNF284 ZNF304	1.43e-03	1192	83	8	chr19q13
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF729 ZNF597 ZNF93 ZNF627 ZNF138 ZNF716 ZNF117 ZNF562 ZNF695 ZNF354A ZNF789 VEZF1 ZNF607 ZNF732 ZNF678 ZNF366 ZNF728 ZNF862 ZNF735 ZNF197 ZNF790 ZNF189 ZNF485 ZNF766 ZNF80 ZNF223 ZNF226 ZNF227 ZNF519 ZNF317 ZNF236 ZNF107 ZNF442 ZNF354B ZNF726 ZNF433 ZNF786 ZNF284 ZNF304 ZNF445	5.75e-37	718	73	40	28
GeneFamily	Rho family GTPases	RHOA RHOB RHOC RND2	1.13e-06	20	73	4	390
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS19 ADAMTS4	2.63e-03	19	73	2	50
GeneFamily	Wnt family\|Endogenous ligands	WNT10B WNT9A	2.63e-03	19	73	2	360
GeneFamily	Zinc fingers CCHC-type\|RNA binding motif containing	ZCCHC9 TUT7	4.54e-03	25	73	2	74
Coexpression	MIKKELSEN_NPC_ICP_WITH_H3K4ME3	ZNF729 COL4A5 ZNF93 ZNF695 ADAMTS4 KCTD20 ZNF317 ZNF107 ZNF354B ZNF726	2.76e-06	497	80	10	MM863
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-8\|TCGA-Bladder / Sample_Type by Project: Shred V9	ZNF138 ZNF562 ZNF66 ZNF107 ZNF726 ZNF786	3.79e-07	150	83	6	1aa9320d97ff10994ea024751790524fe133aba9
Drug	cytotoxic necrotizing factor type 1	RHOA RHOB	1.25e-05	2	81	2	ctd:C060296
Drug	2-methyl-5-(1-methylethenyl)cyclohexanol	RHOA RHOB	1.25e-05	2	81	2	ctd:C534305
Drug	perillic acid	RHOA RHOB	1.25e-05	2	81	2	ctd:C078706
Disease	ulcerative colitis (implicated_via_orthology)	RHOA RHOB RHOC	6.17e-07	7	78	3	DOID:8577 (implicated_via_orthology)
Disease	peroxisomal biogenesis disorder (implicated_via_orthology)	RHOA RHOB RHOC	9.86e-07	8	78	3	DOID:0080377 (implicated_via_orthology)
Disease	triacylglycerol 58:6 measurement	TRAF6 LRP1B	1.91e-04	8	78	2	EFO_0010440
Disease	breastfeeding duration	SLC27A6 PHF11	6.15e-04	14	78	2	EFO_0006864
Disease	breast cancer (is_marker_for)	RHOA RHOB RHOC WNT9A	1.49e-03	185	78	4	DOID:1612 (is_marker_for)
Disease	3-hydroxypropylmercapturic acid measurement	USP34 ZNF627 TRAF6 ZNF519 LRP1B	2.43e-03	352	78	5	EFO_0007014
Disease	ovarian carcinoma (is_marker_for)	RHOA RHOC	2.49e-03	28	78	2	DOID:4001 (is_marker_for)
Disease	Breast Cancer, Familial	PIK3CA GEN1	2.86e-03	30	78	2	C0346153
Disease	disease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement	ADAMTS19 LRP1B	3.45e-03	33	78	2	EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
KTERIGCGSHFCEKL	PI16	136	Q6UXB8
SECSVKCGKGIRHRT	ADAMTS19	1046	Q8TE59
KGCNGTIRLCDHKTK	LRP1B	1086	Q9NZR2
DGKRCRRKDVCKSTH	MATN2	601	O00339
IHKKCIDKIIGRCTG	PRKCD	196	Q05655
IMVGCAKKGERECHI	KCTD20	246	Q7Z5Y7
VLSKHGGKKERCCRA	FYCO1	1211	Q9BQS8
EGKLGCKDCSAVRHL	KIAA1586	156	Q9HCI6
CKDCSAVRHLGSKAE	KIAA1586	161	Q9HCI6
CLGGKTDDKKCTNRV	KLHL41	451	O60662
KKVECEHGFGRVVCK	LY75	1646	O60449
SGHCRKQCKDGEAVK	DEFB118	31	Q96PH6
ICSVKGRKGAKEEHC	PIK3CA	406	P42336
KGCVGCATEERLFHK	CHRNA6	26	Q15825
RCIHAGCDRIIGSKK	ADAMTS4	656	O75173
SKCDCSGIKGEKGER	COL4A5	36	P29400
ADCVKEKGQLTGKHC	CCP110	271	O43303
KDHERNGCRLCKSDK	GEN1	271	Q17RS7
KEKCGEKHICCVPKE	DEFB115	56	Q30KQ5
CVREKGGKVLVHCEA	DUSP5	251	Q16690
KKLVIVGDGACGKTC	RHOC	6	P08134
HLCKDVDGLGQKVCR	FAM181A	316	Q8N9Y4
AGKKVCRVESGKAGC	ARHGAP11A	406	Q6P4F7
KKLVIVGDGACGKTC	RHOA	6	P61586
KKLVVVGDGACGKTC	RHOB	6	P62745
GRCKIVVVGDAECGK	RND2	6	P52198
VVHRGRCKDAGQSKC	SMOC1	81	Q9H4F8
RHTEKKPFKCIECGK	ZNF93	166	P35789
KCHKCEECGKGFVRK	ZNF189	146	O75820
EKIHTGGKLNKCEEC	ZNF107	291	Q9UII5
THKGEKSFECKECGR	ZNF562	281	Q6V9R5
RIHTGEKRYKCKECG	ZNF678	481	Q5SXM1
RVHTEKKTFGCKKCG	ZNF197	586	O14709
KRIHVGEKHCKCEEC	ZNF695	231	Q8IW36
KKCCKRVDECEVHKG	ZNF735	126	P0CB33
RVHLGEKLFKCDVCG	ZNF223	196	Q9UK11
KHAVRCDGVVDCKLK	TMPRSS13	206	Q9BYE2
VRHEGKVSCNICGKL	VEZF1	281	Q14119
IHTGERAFKCEECGK	ZNF519	341	Q8TB69
RKGCKSVDECKGHQG	ZNF138	51	P52744
VIACELKGGKCHKSS	RNASE10	156	Q5GAN6
CGGRVKTEHKALACE	PROM2	136	Q8N271
ERHGKCKKTCIASRD	SEMA6A	516	Q9H2E6
KACIIKSIRDAGHKC	TRAF6	91	Q9Y4K3
KCEECGKAFSVHGRL	ZNF607	366	Q96SK3
KRIHTGEKPCKCEEC	ZNF728	331	P0DKX0
KKCCKSVGECEVHKG	ZNF716	126	A6NP11
HQKKGSFACVICGRK	ZNF654	566	Q8IZM8
HTGEKLFECKECGKA	ZNF627	301	Q7L945
KFCHKRGATVGCDLK	PHF11	111	Q9UIL8
KVSGKDVKRCSVGAC	NSD3	756	Q9BZ95
ACGSIDLVKKCDRHI	ZNF862	736	O60290
VHVGEKLKCDECGKE	ZNF226	301	Q9NYT6
KRIHTGEKPCKCEEC	ZNF726	276	A6NNF4
CECGKGFVKHSKLIE	ZNF786	651	Q8N393
KIHTGEKPCKCSECG	ZNF80	181	P51504
GEKMHECKECGKALS	ZNF442	596	Q9H7R0
TGLQDISIGKKCHKC	ZNF445	966	P59923
LTHKGVKEHKCGICG	ZNF366	441	Q8N895
VKEHKCGICGREFTL	ZNF366	446	Q8N895
TGEKSHECKECGKAF	ZNF790	361	Q6PG37
VIKAGVETTCKCHGV	WNT9A	206	O14904
GGCKLCGSVEHLKKD	ZCCHC9	211	Q8N567
GVHTREKLFKCEECG	ZNF227	736	Q86WZ6
KGCKSVVECKQHKGD	ZNF117	51	Q03924
ELAGTRQHACKACKK	ZNF236	146	Q9UL36
GCESVDKCKVHKRGY	ZNF66	116	Q6ZN08
KIHSGEISHVCKECG	ZNF304	271	Q9HCX3
KIHSGEKKHKCGDCG	ZNF597	176	Q96LX8
HERIHTGEKPCKCKV	ZNF354A	456	O60765
RCHECGKTVRDKSGL	ZNF766	216	Q5HY98
TCSHCGKKVRAEKRA	USP34	2061	Q70CQ2
ENLKRKCKCHGTSGS	WNT10B	241	O00744
HERIHTGEKPCKCKV	ZNF354B	456	Q96LW1
CGHENLELRKSCKRK	ZNF732	106	B4DXR9
SGCVELGATCVLKKK	SLC27A6	276	Q9Y2P4
KRCFICGREGHIKKE	TUT7	1451	Q5VYS8
TGEISHKCKICGKAF	ZNF433	361	Q8N7K0
EKPHKCIECGKTFRK	ZNF485	211	Q8NCK3
HLVKKRVECRQCGKA	ZNF317	496	Q96PQ6
HSGEKTSKCEDCGKR	ZNF284	561	Q2VY69
IHSGEKRHKCLECGK	ZNF789	306	Q5FWF6
IHTAEKPCKCEECGK	ZNF729	901	A6NN14
KKCCKSVGECEVHKG	ZNF722	126	A0A1W2PQL4
KCGARAHKECLGRVD	VAV3	546	Q9UKW4