Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytokine activity

IL24 GDF6 THNSL2

6.37e-04250143GO:0005125
GeneOntologyMolecularFunctionreceptor tyrosine kinase binding

SH2B3 FIZ1

1.76e-0390142GO:0030971
GeneOntologyMolecularFunctionhormone binding

GALR3 ADRA2C

2.30e-03103142GO:0042562
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

SH2B3 FIZ1

4.75e-03149142GO:1990782
GeneOntologyMolecularFunctionreceptor ligand activity

IL24 GDF6 THNSL2

5.94e-03547143GO:0048018
GeneOntologyMolecularFunctionsignaling receptor activator activity

IL24 GDF6 THNSL2

6.15e-03554143GO:0030546
GeneOntologyMolecularFunctionsignaling receptor regulator activity

IL24 GDF6 THNSL2

8.25e-03616143GO:0030545
Domain-

ZSCAN29 ZNF771 KLF8 FIZ1

1.72e-036791543.30.160.60
Domainzf-C2H2

ZSCAN29 ZNF771 KLF8 FIZ1

1.85e-03693154PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZSCAN29 ZNF771 KLF8 FIZ1

1.86e-03694154IPR013087
DomainZINC_FINGER_C2H2_2

ZSCAN29 ZNF771 KLF8 FIZ1

2.78e-03775154PS50157
DomainZINC_FINGER_C2H2_1

ZSCAN29 ZNF771 KLF8 FIZ1

2.81e-03777154PS00028
DomainZnf_C2H2-like

ZSCAN29 ZNF771 KLF8 FIZ1

3.07e-03796154IPR015880
DomainZnf_C2H2

ZSCAN29 ZNF771 KLF8 FIZ1

3.19e-03805154IPR007087
DomainZnF_C2H2

ZSCAN29 ZNF771 KLF8 FIZ1

3.24e-03808154SM00355
DomainPH_dom-like

OBSCN SH2B3 NBEA

4.37e-03426153IPR011993
DomainPH

OBSCN SH2B3

1.41e-02229152PF00169
Pubmed

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

SH2B3 RERE

1.35e-051315224586183
Pubmed

Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.

GALR3 ADRA2C

3.78e-046715220398908
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZSCAN29 ZNF771 KLF8 FIZ1

9.46e-0471812428
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALR3 PODNL1 ADRA2C

2.37e-051711531fb4e11f92b48dc2d6e553c22e2571bbd8c223c6
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALR3 PODNL1 ADRA2C

2.37e-05171153246fc7edcefc47437d1df6029f295aca3b34b2b2
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GALR3 PODNL1 ADRA2C

2.46e-051731533678b300cad4effd7f49bfb043305ed512693848
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GALR3 PODNL1 ADRA2C

2.46e-051731530a355386210a13927ea29b10b64cb059459952d4
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALR3 PODNL1 ADRA2C

3.05e-051861536e3bea4319d2a1bb060fe0cb1bb8bafafa05f83c
ComputationalBlood cells and cancer expression clusters.

OBSCN SH2B3 RERE

1.68e-0340773MODULE_532
ComputationalGenes in the cancer module 459.

OBSCN SH2B3 RERE

1.99e-0343173MODULE_459
ComputationalGenes in the cancer module 378.

OBSCN SH2B3 RERE

2.04e-0343573MODULE_378
ComputationalGenes in the cancer module 317.

OBSCN SH2B3 RERE

2.11e-0344073MODULE_317
ComputationalGenes in the cancer module 255.

OBSCN SH2B3 RERE

2.25e-0345073MODULE_255
ComputationalBlood cells and cancer expression cancer.

OBSCN SH2B3 RERE

2.52e-0346873MODULE_179
ComputationalGenes in the cancer module 37.

OBSCN SH2B3 RERE

2.56e-0347173MODULE_37
ComputationalGenes in the cancer module 136.

OBSCN SH2B3 RERE

2.89e-0349173MODULE_136
ComputationalGenes in the cancer module 69.

OBSCN SH2B3 RERE

3.52e-0352673MODULE_69
DrugBromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A

SH2B3 PODNL1 RERE THNSL2

7.03e-061981546037_DN
Diseaseleft ventricular systolic function measurement

OBSCN SH2B3

1.96e-0444142EFO_0008206
Diseasetonsillectomy risk measurement

SH2B3 NBEA RERE

2.29e-04260143EFO_0007924
Diseaseschizophrenia, anorexia nervosa

MRPS30 RERE

2.33e-0448142MONDO_0005090, MONDO_0005351
Diseaseautoimmune thyroid disease

SH2B3 RERE

1.59e-03126142EFO_0006812
Diseasenon-high density lipoprotein cholesterol measurement

SH2B3 THNSL2 FIZ1

4.19e-03713143EFO_0005689
Diseaseneutrophil count, eosinophil count

SH2B3 RERE

4.46e-03213142EFO_0004833, EFO_0004842
Diseaseneutrophil count, basophil count

SH2B3 RERE

4.92e-03224142EFO_0004833, EFO_0005090
DiseaseMajor Depressive Disorder

IL24 GALR3

5.76e-03243142C1269683
Diseasegranulocyte count

SH2B3 RERE

6.27e-03254142EFO_0007987

Protein segments in the cluster

PeptideGeneStartEntry
SERRSHRSFERSHRR

C2orf16

1826

Q68DN1
RSFKHILFRRRRRGF

ADRA2C

446

P18825
RSFSRSDHLSLHRRR

KLF8

341

O95600
AFRRAARRLHRLFRT

OBSCN

5006

Q5VST9
SARVHHRAFRRLRAL

PODNL1

396

Q6PEZ8
YALASRHFRARFRRL

GALR3

291

O60755
SIRDSAHRRFLLFRR

IL24

161

Q13007
SFRYRSDLRRHFARH

FIZ1

31

Q96SL8
RRRRRTAFASRHGKR

GDF6

331

Q6KF10
LQEHFYLRRRRRVHR

MRPS30

151

Q9NP92
RRRRRFVRNAFGSTH

NBEA

2076

Q8NFP9
FSRFRHREVVHLSRL

THNSL2

81

Q86YJ6
SSRAHRRHRRQAVFR

RERE

446

Q9P2R6
RRFRLSSHFIRHRRA

ZNF771

266

Q7L3S4
QHFRRSLRHIFRRRS

SH2B3

136

Q9UQQ2
SFSRSARLIRHRRIH

ZSCAN29

686

Q8IWY8