Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	GAPVD1 PSD2 PLEKHG6 RAB3IP RALGAPB KNDC1 ARHGAP9 AKAP13 SIPA1 ARAP2 RAPGEFL1	1.55e-05	507	89	11	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	GAPVD1 PSD2 PLEKHG6 RAB3IP RALGAPB KNDC1 ARHGAP9 AKAP13 SIPA1 ARAP2 RAPGEFL1	1.55e-05	507	89	11	GO:0030695
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	GAPVD1 PSD2 PLEKHG6 RAB3IP KNDC1 AKAP13 RAPGEFL1	7.80e-05	231	89	7	GO:0005085
GeneOntologyBiologicalProcess	protein localization involved in establishment of planar polarity	NPHP1 CELSR1	1.84e-05	2	89	2	GO:0090251
GeneOntologyBiologicalProcess	MAPK cascade	PIK3R6 ZFP36L1 ASH1L CEACAM7 ABCC9 AKAP13 TLR9 MAPKBP1 ABCA7 MAP4K2 SIRT3 CCKBR AXIN1 NOD2	4.25e-05	930	89	14	GO:0000165
MousePheno	increased Langerhans cell number	TTC7A CHD9	2.47e-05	2	70	2	MP:0013412
Pubmed	Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development.	FREM2 COL7A1 FREM3	1.73e-07	5	91	3	17251066
Pubmed	The Metabolic Reprogramming of Frem2 Mutant Mice Embryos in Cryptophthalmos Development.	FREM2 HK1 ABCC9	1.44e-06	9	91	3	33490088
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	JPH1 TYK2 TTC7A ZSWIM8 MCM8 ASH1L CHD9 BRD1 SIPA1 DHX34 ABCA7 FAM83H ARAP2	6.74e-06	1116	91	13	31753913
Pubmed	The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process.	MAPKBP1 NOD2	6.77e-06	2	91	2	22700971
Pubmed	Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses.	UNC13D TLR9	2.03e-05	3	91	2	26680738
Pubmed	Characterization of human junctophilin subtype genes.	JPH1 JPH3	2.03e-05	3	91	2	10891348
Pubmed	Toll-like receptor 9, NOD2 and IL23R gene polymorphisms influenced outcome in AML patients transplanted from HLA-identical sibling donors.	TLR9 NOD2	2.03e-05	3	91	2	20622911
Pubmed	Junctophilins: a novel family of junctional membrane complex proteins.	JPH1 JPH3	2.03e-05	3	91	2	10949023
Pubmed	Toll-like receptor 2 deficiency results in impaired antibody responses and septic shock during Borrelia hermsii infection.	TLR9 NOD2	2.03e-05	3	91	2	20696824
Pubmed	Coexpression of junctophilin type 3 and type 4 in brain.	JPH1 JPH3	2.03e-05	3	91	2	14559359
Pubmed	Toll-like receptor 4 gene polymorphism modulates phenotypic expression in patients with hereditary hemochromatosis.	TLR9 NOD2	2.03e-05	3	91	2	19809335
Pubmed	Junctophilins 1, 2, and 3 all support voltage-induced Ca2+ release despite considerable divergence.	JPH1 JPH3	2.03e-05	3	91	2	35089322
Pubmed	Expression of Fraser syndrome genes in normal and polycystic murine kidneys.	FREM2 FREM3	2.03e-05	3	91	2	21993971
Pubmed	Whole-Exome Sequencing of Patients With Posterior Segment Uveitis.	TYK2 NOD2	2.03e-05	3	91	2	32707200
Pubmed	Segmental and restricted localization pattern of Fras1 in the developing meningeal basement membrane in mouse.	FREM2 FREM3	4.05e-05	4	91	2	24101214
Pubmed	Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development.	TLR9 NOD2	4.05e-05	4	91	2	32610078
Pubmed	Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria.	TLR9 NOD2	4.05e-05	4	91	2	22031762
Pubmed	Junctophilin-mediated channel crosstalk essential for cerebellar synaptic plasticity.	JPH1 JPH3	4.05e-05	4	91	2	17347645
Pubmed	Differential localization profile of Fras1/Frem proteins in epithelial basement membranes of newborn and adult mice.	FREM2 FREM3	4.05e-05	4	91	2	18563433
Pubmed	NOD2 variants and antibody response to microbial antigens in Crohn's disease patients and their unaffected relatives.	TLR9 NOD2	4.05e-05	4	91	2	17258734
Pubmed	Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort.	TLR9 NOD2	4.05e-05	4	91	2	19275920
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	TYK2 FREM2 MCM8 ARMC5 NOL6 RALGAPB AKAP13 DHX34 ALG1	5.28e-05	650	91	9	38777146
Pubmed	Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.	PCDHGB4 EMX2 NR2F1	5.41e-05	28	91	3	33523829
Pubmed	Toll-like receptor (TLR) and nucleosome-binding oligomerization domain (NOD) gene polymorphisms and endometrial cancer risk.	TLR9 NOD2	6.74e-05	5	91	2	20646321
Pubmed	Combined carriership of TLR9-1237C and CD14-260T alleles enhances the risk of developing chronic relapsing pouchitis.	TLR9 NOD2	6.74e-05	5	91	2	16437636
Pubmed	Graded expression of Zfp462 in the embryonic mouse cerebral cortex.	EMX2 NR2F1	6.74e-05	5	91	2	17207666
Pubmed	Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.	FREM2 FREM3	6.74e-05	5	91	2	17596926
Pubmed	Characterization of long cDNA clones from human adult spleen.	MICAL1 ARMC5 UNC13D	8.93e-05	33	91	3	11214971
Pubmed	Developmental diversification of cortical inhibitory interneurons.	MYBBP1A CELSR1 ZFP36L1 NR2F1	9.85e-05	91	91	4	29513653
Pubmed	Degree of predicted minor histocompatibility antigen mismatch correlates with poorer clinical outcomes in nonmyeloablative allogeneic hematopoietic cell transplantation.	MYO1G AKAP13	1.01e-04	6	91	2	20353833
Pubmed	Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia.	MYO1G MYO1D	1.01e-04	6	91	2	12486594
Pubmed	Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1.	FREM2 FREM3	1.01e-04	6	91	2	17462874
Pubmed	Spatial control of astrogenesis progression by cortical arealization genes.	EMX2 NR2F1	1.01e-04	6	91	2	35818636
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	GALNT14 CAPN14 HK1 KCNH1 AK5 CEACAM7 SUV39H2 PLK4 ALG1	1.27e-04	730	91	9	34857952
Pubmed	Age-dependent enterocyte invasion and microcolony formation by Salmonella.	TLR9 NOD2	1.41e-04	7	91	2	25210785
Pubmed	Synaptic, transcriptional and chromatin genes disrupted in autism.	RALGAPB ASH1L	1.41e-04	7	91	2	25363760
Pubmed	COUP-TFI: an intrinsic factor for early regionalization of the neocortex.	EMX2 NR2F1	1.41e-04	7	91	2	11511537
Pubmed	Functional expression of pattern recognition receptors in tissues of the human female reproductive tract.	TLR9 NOD2	1.41e-04	7	91	2	19406482
Pubmed	Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.	TTC7A HK1 ALG1 RAPGEFL1	1.42e-04	100	91	4	26073538
Pubmed	Neurotoxicity and gene-expressed profile in brain-injured mice caused by exposure to titanium dioxide nanoparticles.	CSRNP1 DDIT4	1.88e-04	8	91	2	23533084
Pubmed	Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons.	CELSR1 EMX2	2.41e-04	9	91	2	31462532
Pubmed	EMX2 regulates sizes and positioning of the primary sensory and motor areas in neocortex by direct specification of cortical progenitors.	EMX2 NR2F1	2.41e-04	9	91	2	15294144
Pubmed	Chromosomal localization, hematologic characterization, and iron metabolism of the hereditary erythroblastic anemia (hea) mutant mouse.	TTC7A HK1	2.41e-04	9	91	2	15155459
Pubmed	Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome.	TLR9 NOD2	3.01e-04	10	91	2	22323544
Pubmed	Fgf receptor 3 activation promotes selective growth and expansion of occipitotemporal cortex.	EMX2 NR2F1	3.01e-04	10	91	2	19192266
Pubmed	Domineering non-autonomy in Vangl1;Vangl2 double mutants demonstrates intercellular PCP signaling in the vertebrate inner ear.	CELSR1 EMX2	3.01e-04	10	91	2	29510119
Pubmed	Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation.	TLR9 NOD2	3.01e-04	10	91	2	24722226
Pubmed	The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis.	FREM2 FREM3	3.01e-04	10	91	2	15345741
Pubmed	Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors.	ASH1L EMX2	3.01e-04	10	91	2	34145365
Pubmed	Loss-of-function mutations in FREM2 disrupt eye morphogenesis.	FREM2 COL7A1	3.67e-04	11	91	2	30802441
Pubmed	Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography.	EMX2 NR2F1	3.67e-04	11	91	2	22623663
Pubmed	Emx2 patterns the neocortex by regulating FGF positional signaling.	EMX2 NR2F1	3.67e-04	11	91	2	12872126
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SCN11A MYBBP1A HK1 MYO1D FAM186A SYNE2 NOL6 ASH1L PCDHGB4 DLEC1 LRRC43 DTHD1	3.77e-04	1442	91	12	35575683
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GAPVD1 ZFP36L1 SYNE2 RALGAPB AKAP13 BRD1 PLK4 FAM83H ARAP2	4.29e-04	861	91	9	36931259
Pubmed	New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.	JPH1 JPH3	4.39e-04	12	91	2	19095005
Pubmed	A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea.	CELSR1 EMX2	6.04e-04	14	91	2	29784671
Pubmed	Molecular regionalization of the neocortex is disrupted in Fgf8 hypomorphic mutants.	EMX2 NR2F1	6.04e-04	14	91	2	12642494
Pubmed	Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients.	TLR9 NOD2	6.04e-04	14	91	2	20595247
Pubmed	COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling.	EMX2 NR2F1	6.95e-04	15	91	2	18165280
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	TYK2 MICAL1 DDIT4 SGTA SYNE2 DHX34 SUV39H2 PLK4 MAP4K2 NR2F1	7.19e-04	1124	91	10	21900206
Pubmed	WDFY4 is required for cross-presentation in response to viral and tumor antigens.	MYBBP1A MYO1D ARHGAP9 WDFY4	7.69e-04	156	91	4	30409884
Pubmed	Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.	ASH1L SPATA20	7.93e-04	16	91	2	16096065
Pubmed	Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers.	EMX2 NR2F1	7.93e-04	16	91	2	16613831
Pubmed	The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.	CEACAM7 NOD2	7.93e-04	16	91	2	23123061
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	FREM2 FREM3	7.93e-04	16	91	2	15878328
Pubmed	Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.	TLR9 NOD2	7.93e-04	16	91	2	23630357
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	CELSR1 PCDHGB4 PCDH12	9.07e-04	72	91	3	10380929
Pubmed	A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.	FREM2 FREM3	1.01e-03	18	91	2	14730302
Pubmed	The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice.	EMX2 NR2F1	1.01e-03	18	91	2	12421703
Pubmed	Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain.	EMX2 NR2F1	1.01e-03	18	91	2	17150988
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	CELSR1 PCDHGB4 PCDH12	1.10e-03	77	91	3	10835267
Pubmed	Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas.	EMX2 NR2F1	1.12e-03	19	91	2	26387718
Pubmed	Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.	CSRNP1 SCN11A	1.12e-03	19	91	2	24564958
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	CELSR1 PCDHGB4 PCDH12	1.23e-03	80	91	3	10716726
Pubmed	Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.	CELSR1 EMX2 NR2F1	1.32e-03	82	91	3	31073041
Pubmed	Nephronophthisis-Related Ciliopathies	NPHP1 MAPKBP1	1.38e-03	21	91	2	27336129
Pubmed	PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.	FREM2 COL7A1	1.38e-03	21	91	2	27856617
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	GALNT14 ST6GAL2 MCM8 SIRT3 NOD2	1.41e-03	313	91	5	20800603
Pubmed	The cortical hem regulates the size and patterning of neocortex.	EMX2 AXIN1	1.51e-03	22	91	2	24948604
Pubmed	Postmitotic regulation of sensory area patterning in the mammalian neocortex by Lhx2.	EMX2 NR2F1	1.51e-03	22	91	2	25971728
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZSWIM8 SYNE2 CHD9	1.57e-03	87	91	3	12465718
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZSWIM8 MYBBP1A GAPVD1 HK1 MYO1D SYNE2 NOL6	1.65e-03	653	91	7	22586326
Pubmed	Murine embryonic stem cell-derived pyramidal neurons integrate into the cerebral cortex and appropriately project axons to subcortical targets.	EMX2 NR2F1	1.65e-03	23	91	2	20089898
Pubmed	Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.	ABCC9 ABCA7	1.65e-03	23	91	2	10708515
Pubmed	Emx2 directs the development of diencephalon in cooperation with Otx2.	EMX2 NR2F1	1.80e-03	24	91	2	11493561
Pubmed	Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium.	EMX2 NR2F1	1.80e-03	24	91	2	15858069
Pubmed	Chlamydia evasion of neutrophil host defense results in NLRP3 dependent myeloid-mediated sterile inflammation through the purinergic P2X7 receptor.	TLR9 NOD2	1.80e-03	24	91	2	34526512
Pubmed	FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development.	EMX2 NR2F1	1.95e-03	25	91	2	18625063
Pubmed	In vivo validation of late-onset Alzheimer's disease genetic risk factors.	CEACAM7 ABCA7	1.95e-03	25	91	2	38687251
Pubmed	The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map.	EMX2 TENM2 NR2F1	1.96e-03	94	91	3	23431145
Pubmed	The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.	FREM2 CELSR1 FREM3	2.02e-03	95	91	3	20843830
Pubmed	Bhlhb5 regulates the postmitotic acquisition of area identities in layers II-V of the developing neocortex.	EMX2 NR2F1	2.11e-03	26	91	2	18957218
Pubmed	Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.	EMX2 NR2F1	2.28e-03	27	91	2	37995181
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	AKAP13 SERPINA2 WDFY4	2.40e-03	101	91	3	18519826
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TYK2 CELSR1 AKAP13 SPATA20 MAPKBP1 DHX34 ABCA7 FAM83H NOD2	2.44e-03	1105	91	9	35748872
Pubmed	Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.	MYBBP1A NOL6	2.45e-03	28	91	2	19596686
Pubmed	Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells.	EMX2 NR2F1	2.45e-03	28	91	2	27178193
Pubmed	E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs.	MICAL1 TLR9	2.45e-03	28	91	2	30277474
Pubmed	Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease.	TLR9 NOD2	2.45e-03	28	91	2	28410990
Pubmed	A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepithelium.	EMX2 NR2F1	2.45e-03	28	91	2	20668538
GeneFamily	Myosins, class I	MYO1G MYO1D	2.61e-04	8	56	2	1097
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD2 PLEKHG6 ARHGAP9 AKAP13 ARAP2	4.36e-04	206	56	5	682
CoexpressionAtlas	DevelopingKidney_e12.5_renal vesicle_emap-27679_k-means-cluster#2_top-relative-expression-ranked_1000	LARGE2 FREM2 CELSR1 RAB3IP EMX2	5.54e-06	62	87	5	gudmap_developingKidney_e12.5_renal vesicle_1000_k2
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1G CFAP54 UNC13D ARHGAP9 ABCA7 ARAP2	2.09e-06	183	91	6	2e36bbc241682e47e880be21c1503abd7d0c3082
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZSWIM8 DDIT4 CFAP54 MCM8 DHX34	1.88e-05	159	91	5	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1G PIK3R6 ARHGAP9 DTHD1 ARAP2	2.32e-05	166	91	5	fb2cfbf1d0a0f1950dd24c08ba00ebd64b06ceb4
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_T_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1G DDIT4 PIK3R6 ARHGAP9 LRRC43	3.15e-05	177	91	5	89e9ac601bc80bd33141da84056189950e563a1e
ToppCell	Basal\|World / shred by cell class for mouse tongue	LARGE2 FREM2 COL7A1 CELSR1 KCNH1	3.69e-05	183	91	5	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	normal-na-Lymphocytic_NK-NK_dim-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SYNE2 ARHGAP9 LRRC43 DTHD1 ARAP2	3.89e-05	185	91	5	b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NPHP1 CFAP54 KNDC1 DLEC1 DTHD1	3.99e-05	186	91	5	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	wk_15-18-Hematologic-Myeloid-Basophil\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MYO1G PIK3R6 UNC13D ABCA7 RAPGEFL1	4.20e-05	188	91	5	3638d85452de15a060146628fbbad9d2a36feb13
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO1G DDIT4 AK5 ARHGAP9 SIPA1	4.64e-05	192	91	5	1922b0350d3375e67c314dbce8074e5cf986f2ef
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO1G DDIT4 AK5 ARHGAP9 SIPA1	4.64e-05	192	91	5	97c197643e59835c6d45dde9e549c9a1b1bb7288
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO1G DDIT4 AK5 ARHGAP9 SIPA1	4.64e-05	192	91	5	a4d161e3d48bc020e687808b352325ef9d1cc1f3
ToppCell	T/NK_cells-CD8+_Effector_T_cell\|World / Lineage and Cell class	CSRNP1 DDIT4 SYNE2 DTHD1 ARAP2	4.76e-05	193	91	5	79fa0f482cd98642b1d38835cda98622f21e5bd0
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIK3R6 ARHGAP9 LRRC43 DTHD1 ARAP2	4.87e-05	194	91	5	3fe32e38c95135d152acb1624fec1623339e144a
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature2_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	JPH1 PIK3R6 PCDH12 SIPA1 MAP4K2	5.12e-05	196	91	5	b0288e28a6e6222a9e310eb6fe228c04b618db13
ToppCell	T_cells-GZMK+_T_cells\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	MYO1G SYNE2 ARHGAP9 DTHD1 ARAP2	5.12e-05	196	91	5	fa5c7fec9e0dcd7e62ff64704bfdf2a3437a43ba
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPHP1 CFAP54 SYNE2 DLEC1 DTHD1	5.24e-05	197	91	5	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ST6GAL2 DDIT4 COL7A1 CELSR1 TENM2	5.24e-05	197	91	5	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CA11 LARGE2 CELSR1 SYNE2 UNC13D	5.24e-05	197	91	5	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	COVID-19_Severe-NK\|COVID-19_Severe / disease group, cell group and cell class	DDIT4 SYNE2 ARHGAP9 DTHD1 ARAP2	5.37e-05	198	91	5	0cb88084eac25604ec8f9b1497fb8d2433f1971c
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	NPHP1 CFAP54 DLEC1 LRRC43 DTHD1	5.37e-05	198	91	5	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	CD8+_Memory_T_cell-FLU-4\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MYO1G CSRNP1 DDIT4 HK1 PIK3R6	5.50e-05	199	91	5	67ffb50490ed3fa9d2fe08fe9f864eb333f31d92
ToppCell	FLU-Healthy-4\|Healthy / Virus stimulation, Condition and Cluster	MYO1G CSRNP1 DDIT4 HK1 PIK3R6	5.50e-05	199	91	5	40061131e35131873192ca65c0e731a7b3045636
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CA11 CELSR1 MYO1D SYNE2 UNC13D	5.50e-05	199	91	5	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	remission-NK\|remission / disease stage, cell group and cell class	MYO1G DDIT4 SYNE2 AKAP13 DTHD1	5.50e-05	199	91	5	31ed2a314e8f70980ea0686242446d66929288e9
ToppCell	CD8+_Memory_T_cell-FLU\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MYO1G CSRNP1 DDIT4 HK1 PIK3R6	5.50e-05	199	91	5	5d2045074560ec429a9f13f1a3f866ef18884f13
ToppCell	COVID-19_Severe-NK_activated\|COVID-19_Severe / disease group, cell group and cell class	DDIT4 SYNE2 ARHGAP9 DTHD1 ARAP2	5.50e-05	199	91	5	bda28d975f4017ec5bded1d3c72310eabc5aac07
ToppCell	distal-1-Epithelial-Differentiating_Basal\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL7A1 PLEKHG6 RAB3IP EMX2 RAPGEFL1	5.50e-05	199	91	5	fe7d6f70fe337b91b0ad63ea33e5a714d2df87bd
ToppCell	distal-Epithelial-Differentiating_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL7A1 PLEKHG6 RAB3IP EMX2 RAPGEFL1	5.50e-05	199	91	5	286d52f25120293620bdbfd62b832f08e118adf6
ToppCell	mild_COVID-19-NK\|mild_COVID-19 / disease group, cell group and cell class (v2)	DDIT4 SYNE2 ARHGAP9 DTHD1 AXIN1	5.50e-05	199	91	5	4854f25ee436e1cf577744373ffd87b1221d2b88
ToppCell	Control_saline-Hematopoietic_Myeloid-Dendritic_cells-pDC\|Control_saline / Treatment groups by lineage, cell group, cell type	MICAL1 ROGDI SGTA TLR9 WDFY4	5.50e-05	199	91	5	34b95e27581bb127e0b921e9c068dc094cb86b37
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP54 KNDC1 DLEC1 LRRC43 DTHD1	5.63e-05	200	91	5	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	distal-3-Hematologic-Natural_Killer\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DDIT4 AK5 ARHGAP9 SIPA1 DTHD1	5.63e-05	200	91	5	ea11ace5d540c02f23242e48e4d0d7d54999af0e
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CA11 CELSR1 MYO1D SYNE2 UNC13D	5.63e-05	200	91	5	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AK5 ARMC5 MAPKBP1 TENM2 CCKBR	5.63e-05	200	91	5	24e13b6d9d2d8b29df1f02544ea9c50084d9e75c
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP54 KNDC1 DLEC1 LRRC43 DTHD1	5.63e-05	200	91	5	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	Tracheal-10x3prime_v2-Stromal-Peri/Epineurial_\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AK5 ARMC5 MAPKBP1 TENM2 CCKBR	5.63e-05	200	91	5	f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCell	Smart-seq2-bone_marrow_(Smart-seq2)-lymphocytic-B_lymphocytic-plasmablast\|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	COL7A1 MYO1D AK5 CEACAM7	1.38e-04	128	91	4	3c810fc4934dee4de2b8b64a2e152547b08c6f8d
ToppCell	droplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l33\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AGMO TOGARAM1 MAPKBP1 PCDH12	1.74e-04	136	91	4	a43b3db1754c619d328a26a2ba6af4756629a723
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	XKR7 C11orf42 FREM3	1.95e-04	55	91	3	948f26841f18d2d45f74c7c0c7b5be10737a4f43
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr\|Hippocampus / BrainAtlas - Mouse McCarroll V32	XKR7 C11orf42 FREM3	1.95e-04	55	91	3	616be3c334949ab0264293b9771d494381d74fb4
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Prlr-Inhibitory_Gad1Gad2_Id2.Prlr_(Interneuron,_Neurogliaform3)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	XKR7 C11orf42 FREM3	1.95e-04	55	91	3	ed14bdb80cf2ff171b0dfc391ac0b150da344992
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4\|TCGA-Cervix / Sample_Type by Project: Shred V9	NPHP1 XKR7 CFAP54 LRRC43	2.05e-04	142	91	4	369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCell	droplet-Kidney-nan-3m-Lymphocytic-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLR9 WDFY4 PLK4 MAP4K2	2.05e-04	142	91	4	a88bf4bcc80206b16dcc504cc19a3380d01e34a4
ToppCell	COVID-19-Mast_cells-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	CSRNP1 PLK4 JPH3 RAPGEFL1	2.23e-04	145	91	4	5c5fed4620c4c312d1052b8acad910453f7e8fcc
ToppCell	BLOOD--(0)_NK_cell-(0)_NK_cells_(CD56dim-like)\|(0)_NK_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MYO1G AK5 SYNE2 DTHD1	2.23e-04	145	91	4	6dd81d53d006fcc206a10969374a11c372f92133
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PIK3R6 ARHGAP9 WDFY4 NOD2	2.73e-04	153	91	4	83942ef63d21725fa15ed5a91481d1f9936e8f11
ToppCell	PND28-Immune-Immune_Myeloid-DC-maDC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1G COL7A1 ROGDI NUDT17	2.73e-04	153	91	4	b03375c54aa701817c0fc2c3fef32b870169e697
ToppCell	PND28-Immune-Immune_Myeloid-DC-maDC-maDC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYO1G COL7A1 ROGDI NUDT17	2.73e-04	153	91	4	18bd770a18e642581a6df144d47184c1ac383713
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 DLEC1 LRRC43 DTHD1	2.80e-04	154	91	4	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CFAP54 DLEC1 LRRC43 DTHD1	2.80e-04	154	91	4	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP54 DLEC1 DTHD1 MAP10	2.87e-04	155	91	4	441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell	PND03-Immune-Immune_Myeloid-DC-maDC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ROGDI NUDT17 TENM2 NOD2	2.94e-04	156	91	4	095281ea78aefa0ee638191a03f8d6f62a86a9ff
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-fibrocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNT14 PSD2 UNC13D ABCA7	2.94e-04	156	91	4	5b56217336771baf57d791efcb4e206c6aea83b1
ToppCell	PND03-Immune-Immune_Myeloid-DC-maDC-maDC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ROGDI NUDT17 TENM2 NOD2	2.94e-04	156	91	4	29b04143f71a0ecc600ac670abd1d521bee55fe7
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NPHP1 CFAP54 DLEC1 PLK4	3.01e-04	157	91	4	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G MICAL1 NUDT17 WDFY4	3.09e-04	158	91	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G MICAL1 NUDT17 WDFY4	3.24e-04	160	91	4	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G UNC13D TLR9 SUV39H2	3.24e-04	160	91	4	cfd005e98944817458e8ef9e0c436d77f50c1ad1
ToppCell	T_cells-Tph_and_Tfh\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SYNE2 ARHGAP9 DTHD1 ARAP2	3.39e-04	162	91	4	146058f2d60846376078916055d08f68562e3a7c
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	ZSWIM8 COL7A1 CELSR1 UNC13D	3.55e-04	164	91	4	d7053de88ef8e42cac6726a40e72f212659ee034
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FREM2 CELSR1 CFAP54 DLEC1	3.64e-04	165	91	4	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FREM2 CELSR1 CFAP54 DLEC1	3.64e-04	165	91	4	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	NS-critical-d_0-4-Epithelial-unknown_epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	JPH1 RAB3IP SUV39H2 RPS6KL1	3.72e-04	166	91	4	dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ST6GAL2 PCDH12 SIPA1 MAP4K2	3.81e-04	167	91	4	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ST6GAL2 PCDH12 SIPA1 MAP4K2	3.81e-04	167	91	4	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ST6GAL2 PCDH12 SIPA1 MAP4K2	3.81e-04	167	91	4	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ST6GAL2 PCDH12 SIPA1 MAP4K2	3.81e-04	167	91	4	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	droplet-Lung-LUNG-30m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XKR7 ROGDI MCM8 NUDT17	3.89e-04	168	91	4	0e8b0e6399c6c82c9c0e546f7316f902de0765d3
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-B_cells-Pro-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TTC7A GALNT14 CSRNP1 MAP4K2	3.89e-04	168	91	4	c833e3311af2582787d3ff2ad59d802fff865f8f
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLEKHG6 CEACAM7 ABCA7 RAPGEFL1	3.89e-04	168	91	4	de0b00bc405c898d08a06b2e585fb62c0ab9a66e
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CELSR1 UNC13D SPATA20 ARAP2	3.98e-04	169	91	4	665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell	390C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CELSR1 UNC13D SPATA20 ARAP2	3.98e-04	169	91	4	6614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell	Basal_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	COL7A1 PSD2 ARAP2 RAPGEFL1	4.07e-04	170	91	4	776d4224a682b6c648041827efd69794f88906f0
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G ARHGAP9 SUV39H2 NOD2	4.07e-04	170	91	4	45de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1G PIK3R6 ARHGAP9 ARAP2	4.16e-04	171	91	4	f16cb64b8844c2668922c786888efaa9f873afcc
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	CFAP54 DLEC1 LRRC43 WDFY4	4.16e-04	171	91	4	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NPHP1 CELSR1 KNDC1 PLK4	4.16e-04	171	91	4	1854a777d9eb9d3fc3ed3632332a6f89ce8131da
ToppCell	facs-Lung-18m-Hematologic-myeloid\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TTC7A MYO1G ARHGAP9 WDFY4	4.16e-04	171	91	4	4ad28ecfde3d529a09b80be908c446bd5274518e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 ST6GAL2 CELSR1 CFAP54	4.25e-04	172	91	4	0c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT14 ST6GAL2 CELSR1 CFAP54	4.25e-04	172	91	4	eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYK2 MYO1G ROGDI NUDT17	4.25e-04	172	91	4	c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCell	facs-Lung-EPCAM-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TYK2 MYO1G ROGDI NUDT17	4.25e-04	172	91	4	7c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCell	facs-Lung-EPCAM-18m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC7A MYO1G ARHGAP9 WDFY4	4.35e-04	173	91	4	50b25b7f8f29b60c22782a4492fe4b089fe7d69d
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LARGE2 FREM2 ST6GAL2 KCNH1	4.44e-04	174	91	4	b7f5492ce8098f7eb0aef30ee558d00738d59d0e
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LARGE2 FREM2 ST6GAL2 KCNH1	4.44e-04	174	91	4	71730503be3d9c839c4c9e950145e2101d682a1c
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	LARGE2 FREM2 ST6GAL2 KCNH1	4.44e-04	174	91	4	ee8ac51fa0b426ad7b7453371bb79c8bf8c1d358
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like\|blood / Manually curated celltypes from each tissue	CSRNP1 DDIT4 MYO1D SYNE2	4.44e-04	174	91	4	51be6f29308c01593978cbee92114151a5916c9c
ToppCell	BAL-Mild-Epithelial-Epithelial-AT1/AT2-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LARGE2 FREM2 ST6GAL2 KCNH1	4.44e-04	174	91	4	cafe4d6b5f08d8888e9db6e196c66df991c03e7b
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CA11 FREM2 ST6GAL2 EMX2	4.44e-04	174	91	4	4da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FAM186A PCDHGB4 FREM3	4.49e-04	73	91	3	cc89c94a3768b02036757dea86989d9284b214b9
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FAM186A PCDHGB4 FREM3	4.49e-04	73	91	3	6f28d52700bab981c8a3664ba4762f3572f7e788
ToppCell	Hippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sfrp2-Inhibitory_Neuron.Gad1Gad2_Id2.Sfrp2_(Interneuron,_Neurogliaform1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FAM186A PCDHGB4 FREM3	4.49e-04	73	91	3	ae80fcf3544c18fe0318a8311e96f2448f7cb03c
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT\|blood / Manually curated celltypes from each tissue	CSRNP1 DDIT4 MYO1D SYNE2	4.54e-04	175	91	4	b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCell	E18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	JPH1 LARGE2 MAP4K2 FAM83H	4.54e-04	175	91	4	711ace94fa9a763c6ae48171a690953f25deebe4
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTC7A WDFY4 SUV39H2 ABCA7	4.64e-04	176	91	4	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCDH12 MAP4K2 NR2F1 JPH3	4.64e-04	176	91	4	5d3b2395bb842eea39175f5af6a4c76527e2fc31
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a6.Fezf2-3110035E14Rik_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CBY3 FAM186A DLEC1	4.68e-04	74	91	3	83b762542508f9d6407e4b0087d70bea81a8fc7d
ToppCell	systemic_lupus_erythematosus-managed-Lymphocytic_NK-T_mait-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DDIT4 PSD2 SYNE2 BRD1	4.74e-04	177	91	4	605f71515c877bb4de4121675ec8c1318a2500a7
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM8 ABCC9 SIPA1 NR2F1	4.74e-04	177	91	4	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM8 ABCC9 SIPA1 NR2F1	4.74e-04	177	91	4	e7b1f3092e6b8d0d580f82648035f5ad12be6961
Computational	Genes in the cancer module 430.	TYK2 TTC7A SIPA1 MAP4K2	1.10e-04	55	49	4	MODULE_430
Disease	bronchiolitis obliterans (is_implicated_in)	TLR9 NOD2	5.38e-05	4	89	2	DOID:2799 (is_implicated_in)
Disease	Nephronophthisis, familial juvenile	NPHP1 MAPKBP1	1.87e-04	7	89	2	C1855681
Disease	obsolete_red blood cell distribution width	CA11 PMS2P1 HK1 MYO1D ZFP36L1 SYNE2 UNC13D AKAP13 SIPA1 FREM3 SERPINA2 ABCA7 AXIN1	1.96e-04	1347	89	13	EFO_0005192
Disease	Lewy body dementia	ASH1L DHX34 JPH3	2.24e-04	39	89	3	EFO_0006792
Disease	ciliopathy (implicated_via_orthology)	TOGARAM1 PLK4 MAP4K2	2.42e-04	40	89	3	DOID:0060340 (implicated_via_orthology)
Disease	reticulocyte count	MYO1G HK1 MYO1D ZFP36L1 SYNE2 ASH1L PCDHGB4 ARHGAP9 SPATA20 SIPA1 SERPINA2	3.06e-04	1045	89	11	EFO_0007986
Disease	Crohn's disease of large bowel	TYK2 TLR9 NOD2	3.21e-04	44	89	3	C0156147
Disease	IIeocolitis	TYK2 TLR9 NOD2	3.21e-04	44	89	3	C0949272
Disease	Crohn's disease of the ileum	TYK2 TLR9 NOD2	3.21e-04	44	89	3	C0267380
Disease	Regional enteritis	TYK2 TLR9 NOD2	3.21e-04	44	89	3	C0678202
Disease	reticulocyte measurement	HK1 MYO1D AK5 SYNE2 ASH1L PCDHGB4 ARHGAP9 AKAP13 SIPA1 CORO7 SERPINA2	3.26e-04	1053	89	11	EFO_0010700
Disease	Crohn Disease	TYK2 TLR9 NOD2	4.69e-04	50	89	3	C0010346
Disease	hair colour measurement	FREM2 DDIT4 ZFP36L1 KCNH1 SYNE2 UNC13D AKAP13 JPH3	5.46e-04	615	89	8	EFO_0007822
Disease	Ischemic stroke, fibrinogen measurement	ZFP36L1 CHD9 JPH3	6.21e-04	55	89	3	EFO_0004623, HP_0002140
Disease	hemoglobin A1 measurement	HK1 SYNE2 AGMO UNC13D AKAP13 SERPINA2 MAP4K2	1.01e-03	520	89	7	EFO_0007629
Disease	Microcephaly	AGMO PCDH12 PLK4	1.11e-03	67	89	3	C0025958
Disease	allergic rhinitis (is_marker_for)	TLR9 NOD2	1.19e-03	17	89	2	DOID:4481 (is_marker_for)
Disease	drug-Induced dyskinesia, response to levodopa	GALNT14 LINC01549	1.33e-03	18	89	2	EFO_0010747, EFO_1000904
Disease	BMI-adjusted fasting blood glucose measurement	AGMO MAP4K2	2.18e-03	23	89	2	EFO_0008036
Disease	skin aging measurement	SYNE2 BRD1 DTHD1 ARAP2	2.23e-03	181	89	4	EFO_0008006
Disease	initial pursuit acceleration	TTC7A CBY3 PCDH12	2.34e-03	87	89	3	EFO_0008434
Disease	hair color	FREM2 DDIT4 ZFP36L1 KCNH1 SYNE2	2.54e-03	311	89	5	EFO_0003924
Disease	mean reticulocyte volume	TTC7A HK1 ZFP36L1 AK5 AKAP13 SERPINA2 ABCA7 SIRT3	2.86e-03	799	89	8	EFO_0010701
Disease	albuminuria	ZFP36L1 AK5 MAPKBP1	2.92e-03	94	89	3	EFO_0004285
Disease	transforming growth factor beta measurement	DLEC1 EMX2	3.01e-03	27	89	2	EFO_0004818

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLLRRLQSSLQSQRS	BRD1	491	O95696
LLRQEAFLTTSRTPL	ASH1L	1446	Q9NR48
ISPQSRLTLARSLVL	CFAP54	2471	Q96N23
TRLRERPALLVSSTS	ALG1	271	Q9BT22
LSRLPSLFFRSIELT	AGMO	81	Q6ZNB7
LVLSERALTRSLSRP	AKAP13	2551	Q12802
RALTRSLSRPSSLIE	AKAP13	2556	Q12802
NETPLSRALLALRTR	ARMC5	36	Q96C12
RSRLSIILQDPILFS	ABCC9	1386	O60706
RSKLVSRPSRSFLLR	ARAP2	271	Q8WZ64
RLLAPSTSLLLRADR	AP5S1	151	Q9NUS5
LLVSPRLLLSTDNRT	CEACAM7	186	Q14002
PFLSRLLNRDTITRI	CA11	196	O75493
RLVARSAPTALSRRL	CELSR1	91	Q9NYQ6
LSRRLRTVTNAFLLS	CCKBR	81	P32239
TESQLARTRSPLLSR	CBY3	141	A6NI87
VFLRVLSRSLPLFLT	ABCA7	541	Q8IZY2
RRSLRPCSVLVSLLQ	CAPN14	391	A8MX76
DSLSRLRSPSVLEVR	RAB3IP	156	Q96QF0
LLRLPSLRTVSSSVI	NR2F1	371	P10589
RLTARRELLSLPATS	LARGE2	276	Q8N3Y3
ILAIALRLRRSSSPA	PCDHGB4	706	Q9UN71
ESASLRTRIPLDRAL	PCDH12	146	Q9NPG4
RLTQRIIPRRFALST	MAP4K2	576	Q12851
SRLLSQLERPLTFTR	MAP10	186	Q9P2G4
SPITTRQLESLIRLT	MCM8	706	Q9UJA3
VLLTRRARTLSVSPN	NUDT17	106	P0C025
RLLQRSRSSLPVDDT	AK5	496	Q9Y6K8
SFTPLSILKRARRER	CSRNP1	66	Q96S65
RSLPLSSFTQRDLRL	FREM2	376	Q5SZK8
SRLRENPRLIASSLV	GAPVD1	101	Q14C86
RSPLRTSLASLRSEQ	JPH1	156	Q9HDC5
LRLRQSSLEPVAFRL	CORO7	801	P57737
LLAAQLTRLRPSASR	PEAK3	376	Q6ZS72
RSLEQRSLILSPRLE	LINC01549	16	A6NIU2
TAASLRLERDTRQLP	NOL6	821	Q9H6R4
RLERDTRQLPLLTSA	NOL6	826	Q9H6R4
RILTSRRSSQSPQEL	KCNH1	956	O95259
IRLSSPERQRLSSLN	MICAL1	806	Q8TDZ2
RPRRRATTSLLTLLL	PMS2P1	106	A4D2B8
LRRLVPDSDVRFLLS	HK1	431	P19367
PLLSIIRRSLRSSSS	MYBBP1A	851	Q9BQG0
TLLRTIRSVLNRTPT	GALNT14	126	Q96FL9
RALRRDPRLTFSTLE	PLEKHG6	611	Q3KR16
ITRAIESSPDRRLTL	FOXO3B	251	A0A2Z4LIS9
LQALSRPDTRLQLTT	SERPINA2	126	P20848
PTQSALTTRLRRLIT	CHD9	1776	Q3L8U1
PTFQLTLVLRLDSRL	DDIT4	171	Q9NX09
LLLETAAPRVSSSRR	AXIN1	271	O15169
SLSSTLPLRRSTIQL	DTHD1	696	Q6ZMT9
SISSRFLLQVQTRPL	MAPKBP1	1096	O60336
RLRKVQTFPRLLSDS	KNDC1	301	Q76NI1
FSILRTLLPLVSRRV	COL7A1	201	Q02388
RIRTAFSPSQLLRLE	EMX2	156	Q04743
QSIISRLSPSLRLSL	FAM186A	1726	A6NE01
RLNPLVQRSSRLRSS	FAM83H	671	Q6ZRV2
LILTNRSPIRTRFSL	DLEC1	1116	Q9Y238
VRIPALQSLLLFSRS	DHX34	896	Q14147
LNRRSRNVLSLLPET	NPHP1	556	O15259
SFLRELAIRNPLTIT	LRRC43	106	Q8N309
RSPRISLRSSSLLDV	FREM3	941	P0C091
LQLTRARNRLTTPAT	ROGDI	151	Q9GZN7
LIEQLRSQIRSRTPS	SGTA	291	O43765
PESTELQSRLRQLSL	SYNE2	6626	Q8WXH0
VLFLRPRSQLRLSAD	PIK3R6	301	Q5UE93
SFLPRTLSLRNSISR	SIPA1	901	Q96FS4
SSLSFLETRRLLPVQ	ST6GAL2	41	Q96JF0
TEAVRSSVPRLLINR	SIRT3	331	Q9NTG7
RIFPSRNVTSILELR	TENM2	1261	Q9NT68
LRRNPADRLSLSSVL	PLK4	246	O00444
TSTAREPQLLRLLRS	C11orf42	176	Q8N5U0
LDNSRRLPIFSRLSI	ZFP36L1	321	Q07352
LRLLETFLRSAPQLV	XKR7	231	Q5GH72
TPSQRARRLLDLATV	NOD2	176	Q9HC29
FRSLDETTLRPLARL	TLR9	376	Q9NR96
PLRRSISSSRSENVL	PSD2	221	Q9BQI7
SFLSRQLPFLSTLRR	SPATA20	741	Q8TB22
NLDTRLPRIALFSTR	SUV39H2	346	Q9H5I1
RLSLQNLSRLTDTLP	WDFY4	266	Q6ZS81
LVSKPLLRLSSRRSS	ARHGAP9	486	Q9BRR9
RLRPIRTLSSAVEQL	RPS6KL1	136	Q9Y6S9
NPTELRRSSINILLS	RALGAPB	606	Q86X10
LRAPVSESLSRLQRD	ZSWIM8	216	A7E2V4
LERLPNSIASRFRLT	TTC7A	176	Q9ULT0
FRTLRALRPLRALSQ	SCN11A	1146	Q9UI33
DTRLLQLLRTARDPS	TOGARAM1	96	Q9Y4F4
RQSVSRLLLPAFLRE	RAPGEFL1	56	Q9UHV5
VSDSPARLQSLLRVL	UNC13D	421	Q70J99
RPSFRTILRDLTRLQ	TYK2	856	P29597
IRSPLRTSINSLRSE	JPH3	156	Q8WXH2
PRTRFLSKQLTALRE	LEUTX	11	A8MZ59
IRTPRTLFTLEELRA	MYO1D	681	O94832
LFIRSPRTLVTLEQS	MYO1G	691	B0I1T2