Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC3 ABCC6

6.92e-058322GO:0015431
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC3 ABCC6

1.11e-0410322GO:0043225
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC3 ABCC6

2.58e-0415322GO:0008559
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

GPR83 VIPR1 INPP5K

1.24e-03133323GO:0008528
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC3 ABCC6

1.35e-0334322GO:0042910
GeneOntologyMolecularFunctionpeptide receptor activity

GPR83 VIPR1 INPP5K

1.44e-03140323GO:0001653
GeneOntologyBiologicalProcessleukotriene transport

ABCC3 ABCC6

4.57e-057312GO:0071716
DomainMultidrug-R_assoc

ABCC3 ABCC6

1.49e-054302IPR005292
DomainABC_membrane

ABCC3 ABCC6

6.73e-0424302PF00664
DomainABC_TM1F

ABCC3 ABCC6

9.19e-0428302PS50929
DomainABC1_TM_dom

ABCC3 ABCC6

9.19e-0428302IPR011527
DomainABC_transporter_CS

ABCC3 ABCC6

2.06e-0342302IPR017871
DomainABC_TRANSPORTER_2

ABCC3 ABCC6

2.69e-0348302PS50893
DomainABC_tran

ABCC3 ABCC6

2.69e-0348302PF00005
DomainABC_TRANSPORTER_1

ABCC3 ABCC6

2.80e-0349302PS00211
DomainABC_transporter-like

ABCC3 ABCC6

2.91e-0350302IPR003439
DomainSushi

SVEP1 VCAN

3.15e-0352302PF00084
DomainCCP

SVEP1 VCAN

3.39e-0354302SM00032
DomainSUSHI

SVEP1 VCAN

3.64e-0356302PS50923
DomainSushi_SCR_CCP_dom

SVEP1 VCAN

3.77e-0357302IPR000436
DomainConA-like_dom

CLSTN3 ALK SVEP1

5.11e-03219303IPR013320
Pubmed

Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.

ABCC3 ABCC6

2.46e-06332217845218
Pubmed

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.

ABCC3 ABCC6

2.29e-05832215802388
Pubmed

The Metabolic Reprogramming of Frem2 Mutant Mice Embryos in Cryptophthalmos Development.

ABCC3 ABCC6

2.94e-05932233490088
Pubmed

Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.

ABCC3 ABCC6

9.76e-051632235307651
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC3 ABCC6

1.87e-04223228894702
Pubmed

Tagging genes with cassette-exchange sites.

MACF1 HARBI1 MARCHF6 SLC49A4

2.46e-0433532415741177
Cytoband15q15.2

TMEM62 STARD9

5.61e-051632215q15.2
CytobandEnsembl 112 genes in cytogenetic band chr12p13

CLSTN3 TAS2R30 IFFO1

1.89e-03353323chr12p13
CytobandEnsembl 112 genes in cytogenetic band chr15q15

TMEM62 STARD9

4.74e-03147322chr15q15
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC6

1.54e-0413262807
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

SVEP1 VCAN

3.02e-03572621179
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MACF1 SVEP1 VCAN

8.90e-06184324d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

MACF1 NEO1 SVEP1 VCAN

9.69e-061883243f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

MACF1 NEO1 SVEP1 VCAN

1.03e-051913243379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellP07-Mesenchymal-mesenchymal_fibroblast|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MACF1 NEO1 SVEP1 VCAN

1.03e-05191324a05e9a7eb137d804570dd7d8905975d735738767
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 SVEP1 VCAN

1.05e-05192324de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 SVEP1 VCAN

1.05e-0519232425492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 SVEP1 VCAN

1.12e-05195324cbe518b465b4ef32797ae6b608219207c08493df
ToppCellPND03-Mesenchymal-Mesenchymal_structural|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 SVEP1 VCAN

1.12e-05195324136b06b0931a69b1241101f68c01c44c70365fd9
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 SVEP1 VCAN

1.12e-051953241f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 SVEP1 VCAN

1.12e-0519532410f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCellPND10-Mesenchymal-Mesenchymal_structural|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 SVEP1 VCAN

1.12e-0519532411d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ABCC3 MACF1 SVEP1 VCAN

1.16e-051973240034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.19e-051983240a4b19c3d5e65ecd24fc2ce80ac5276c813282c7
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.21e-0519932430d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.21e-05199324e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

CLSTN3 MYO16 SVEP1 VCAN

1.21e-05199324fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.21e-05199324c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CLSTN3 MYO16 SVEP1 VCAN

1.21e-051993248b86c69aaf60feff53aa782559cfece7342a23de
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.21e-05199324a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.24e-052003249b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.24e-0520032444a68bacdb3d5bf563bd35952176995850933a81
ToppCellControl_saline-Mesenchymal_fibroblastic|Control_saline / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.24e-0520032464ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.24e-05200324a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts|Control_saline / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.24e-05200324a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.24e-05200324dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

MACF1 MYO16 SVEP1 VCAN

1.24e-05200324bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCelldroplet-Skin-nan-18m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 MYO16 SVEP1

9.11e-051223238f675dc341b3f6e22f7e52c34d167d9e37df0982
ToppCelldroplet-Skin-nan-18m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 MYO16 SVEP1

9.11e-05122323c7e81504e62d132624ec15b7d38dc5b6493a37a4
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-Uncommitted_AE_Progenitor|E18.5-samps / Age Group, Lineage, Cell class and subclass

TMEM62 ALK MYO16

9.33e-051233235f002f5180fe47fe57ab888b5f0319df99ab2c59
ToppCelldroplet-Skin-nan-18m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 MYO16 SVEP1

9.79e-051253235a309ce803d2b8efd791eb21808121bf5fc3ea8e
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO16 SVEP1 SLC6A17

9.79e-05125323b162a5bfbb8ac5e65e13578fef9de442a9e4fd8b
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

NEO1 SVEP1 VCAN

1.65e-04149323651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC17A4 VIPR1 ABCC3

1.85e-041553235fabe24a784f0be46040ffc886eabd8d5ce78121
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC3 CLSTN3 SVEP1

1.96e-041583237f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellBronchial_Biopsy-Immune-Neutrophils|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

VIPR1 CLSTN3 ABCC6

2.10e-04162323985adca17b0c99563feef7910f3da5df31e636b6
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

FAXDC2 SVEP1 MYBL2

2.10e-04162323e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

FAXDC2 SVEP1 MYBL2

2.10e-04162323ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage|343B / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 TAS2R30 VCAN

2.18e-04164323057ca87847373eff7fe97dd9f4358509e66ca4c3
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 STARD9 SVEP1

2.38e-0416932316c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|metastatic_Brain / Location, Cell class and cell subclass

GPR83 HARBI1 MYBL2

2.38e-0416932371f6761b9927f352e0ccc221ca373319915f4184
ToppCelldroplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IFFO1 SVEP1 VCAN

2.43e-0417032310e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM62 NPHP3 HARBI1

2.51e-04172323356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM62 NPHP3 HARBI1

2.51e-0417232346fadeee483fdf8402df92ec98575a09c6c15b16
ToppCellfacs-Thymus-Flowthrough-3m-Myeloid-macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM62 NPHP3 HARBI1

2.51e-04172323438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

2.51e-041723230f2771e1e24fd2235ceb96663f0513b4dd6552d1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-2_PAX6_SCGN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

2.55e-0417332333170a1cc0bc87504d0501fc257a32ff17e02314
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC17A4 VIPR1 ABCC3

2.55e-0417332381c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 VCAN

2.64e-041753234d42a97c450e919a409477a7db85e2668f0d473b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR83 ALK MYO16

2.64e-04175323955f10982a487e12cdc3a9f80b3be06bf6c59de7
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MACF1 NEO1 VCAN

2.69e-04176323d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

2.78e-04178323e86ed30652c2de70f16430f04b78789b87df4af2
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

IFFO1 SVEP1 VCAN

2.78e-04178323142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC17A4 ABCC3 ABCC6

2.82e-0417932358ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM4 ECT2L MARCHF6

2.82e-04179323dd94ebe69ade6f51b94058abe066216f0de9feda
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

2.82e-041793230b6731d9554f8bed1899c165a50e6b329ea19a6d
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIPR1 ABCC3 NEO1

2.87e-041803237c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ECT2L MYO16 SVEP1

2.87e-0418032308ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ECT2L MYO16 SVEP1

2.87e-041803239b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK ABCC6 MYO16

2.91e-041813239842537f9a607d8557c43790008d175edab1f32c
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

2.91e-0418132303a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

MACF1 NEO1 SVEP1

2.96e-04182323ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 FAXDC2 VCAN

3.06e-04184323a2191dd5546efd357b23e625beb3c5820476f243
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 VCAN

3.11e-041853236e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

3.11e-0418532379cff4f3c6ae8e5ea60e8eae082b9275f2679ee9
ToppCellmetastatic_Lymph_Node-B_lymphocytes-MALT_B_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

HERPUD1 ALG14 MYBL2

3.11e-04185323bb87fa174f80706fe7be60d3b9fc3e2a6b373038
ToppCellMild-CD4+_T|Mild / Disease group and Cell class

VIPR1 NEO1 MYO16

3.11e-04185323c28ecb63146de1b02418e5a4fad0ae7c2b66a41d
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 FAXDC2 VCAN

3.21e-0418732397e520705491c8f52a32025311a9fa7b9176979a
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 ALK VCAN

3.21e-04187323daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

3.21e-04187323d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 ALK VCAN

3.21e-041873235b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 FAXDC2 VCAN

3.26e-0418832360242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SHROOM4 VIPR1 FAXDC2

3.26e-04188323fe7143c36e4a883745862d3c3147cf751b440e46
ToppCellFibroblast-A|World / shred on cell class and cell subclass (v4)

MACF1 NEO1 VCAN

3.26e-041883236740bed5fb8f45b6eea17041894b804214c2a4ae
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

SHROOM4 VIPR1 FAXDC2

3.26e-04188323cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

3.26e-04188323ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 VCAN

3.31e-04189323979b7fa947538aa7ca4a219263da2575869a2caa
ToppCellLAM-Endothelial-VasEndo-1|LAM / Condition, Lineage and Cell class

SHROOM4 VIPR1 FAXDC2

3.31e-04189323454e64b1ee93edebbc1576fbf7c3a6db332fa927
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GPR83 ALK MYO16

3.31e-0418932399a13b1b669b0cd36e3096632351d9ade25d1173
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC17A4 ABCC6 VCAN

3.31e-0418932328b502611829e4a24caff2562545c7db97686099
ToppCellfacs-Skin-nan-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO16 SVEP1 SLC6A17

3.31e-0418932329287525120be2953b76881ba3cfc4379c265e7a
ToppCellfacs-Skin-nan-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO16 SVEP1 SLC6A17

3.31e-041893237150dad9a92a715487c2d8130fa01b752ea69663
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

MACF1 SVEP1 VCAN

3.31e-041893230c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellfacs-Skin-nan-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO16 SVEP1 SLC6A17

3.31e-041893236e4c0effd5192fd00052abc048fdb87a74fb6554
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MACF1 NEO1 VCAN

3.31e-04189323dc5164591dea45b420798b94dda211be03daa70c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 SVEP1

3.36e-041903232f54da2bee411f8868348a4c37034184b8f58a89
ToppCellmetastatic_Lymph_Node-B_lymphocytes-MALT_B_cells|B_lymphocytes / Location, Cell class and cell subclass

HERPUD1 ALG14 MYBL2

3.36e-041903235ec49cc7692053c1a525ca9137c996ccd2794e1c
ToppCellControl-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

SHROOM4 VIPR1 NEO1

3.36e-041903237f3f419fffe02934b6f27b697f7a6401072491ed
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

MACF1 NEO1 VCAN

3.36e-041903231196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ALK MYO16 VCAN

3.36e-04190323be2b184a3559da41ba387ae0fdbeb9ae532868a5
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SLC17A4 ABCC3 ABCC6

3.36e-04190323b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC17A4 ABCC3 ABCC6

3.36e-04190323989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellIPF-Endothelial-VE_Capillary_A|IPF / Disease state, Lineage and Cell class

SHROOM4 VIPR1 FAXDC2

3.36e-04190323b4e35cbfe4d43d2cd51f29c3085e4d9b1012e6f0
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO16 SVEP1 VCAN

3.36e-0419032345df8fee00f8949937863159d7aa042e72748d9b
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MACF1 CLSTN3 STARD9

3.41e-041913237a4fe96989f72159385270c712342ba3e1ca6fc3
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO16 SVEP1 VCAN

3.41e-04191323b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLSTN3 HERPUD1 SLC49A4

3.41e-041913234187f31ec399b4c7c3608e94e3c32b7a54b1c3d4
ToppCellPBMC-Convalescent-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HERPUD1 ALG14 MYBL2

3.41e-04191323dd1d38a531a272a746c16807688013d29cab823a
ToppCellControl-Lymphoid_T/NK-NK_CD56bright|Control / Disease group, lineage and cell class

MACF1 CLSTN3 STARD9

3.41e-04191323e842f29bc03ed6734b2a7b975e7830a498f2743c
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MACF1 CLSTN3 STARD9

3.41e-04191323f1935e8f8467a2bc30588b7f2cc3b94e9c83b268
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MACF1 CLSTN3 STARD9

3.41e-04191323c023ca893ceae19b54967096f6e2588dc39fa268
DrugLeflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A

VIPR1 IFFO1 ALK ABCC6 MARCHF6

6.05e-061943156102_UP
Druggrepafloxacin glucuronide

ABCC3 ABCC6

1.07e-054312CID000443296
DrugAC1LAHTK

ABCC3 ABCC6

2.68e-056312CID000468713
DrugAC1NB6SN

ABCC3 ABCC6

2.68e-056312CID004488324
DrugBSOCOES

VIPR1 HERPUD1

2.68e-056312CID000093771
Drugcalcein AM

ABCC3 ABCC6

5.00e-058312ctd:C085925
DrugImido Diphosphate

VIPR1 INPP5K

9.79e-0511312CID000163106
Drugmebrofenin

ABCC3 ALK

9.79e-0511312CID000054158
DrugLoperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; PC3; HT_HG-U133A

FAXDC2 CLSTN3 HERPUD1 MARCHF6

1.21e-041893144672_UP
DrugDoxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; MCF7; HT_HG-U133A

SLC17A4 FAXDC2 ALK VCAN

1.26e-041913143291_UP
DrugGuaifenesin [93-14-1]; Down 200; 20.2uM; PC3; HT_HG-U133A

CLSTN3 NEO1 IFFO1 SVEP1

1.32e-041933143814_DN
DrugNovobiocin sodium salt [1476-53-5]; Up 200; 6.4uM; PC3; HT_HG-U133A

FAXDC2 ABCC3 SVEP1 VCAN

1.32e-041933144569_UP
Drugharmol sulfate

ABCC3 ABCC6

1.39e-0413312CID005488302
DrugOrphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A

ABCC3 CLSTN3 ALK SVEP1

1.42e-041973143801_DN
DrugMexiletine hydrochloride [5370-01-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A

SLC17A4 VIPR1 FAXDC2 CLSTN3

1.42e-041973142324_UP
DrugDicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; PC3; HT_HG-U133A

SLITRK3 IFFO1 ABCC6 MARCHF6

1.42e-041973146666_UP
DrugCefadroxil [50370-12-2]; Up 200; 11uM; MCF7; HT_HG-U133A

SLC17A4 ALK ABCC6 VCAN

1.42e-041973144161_UP
DrugPNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A

ABCC3 ALK SVEP1 VCAN

1.42e-041973144757_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT_HG-U133A

VIPR1 ABCC3 INPP5K VCAN

1.45e-041983145214_UP
DrugParomomycin sulfate [1263-89-4]; Up 200; 5.6uM; MCF7; HT_HG-U133A

SLC17A4 FAXDC2 CLSTN3 SVEP1

1.45e-041983143356_UP
DrugBicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A

VIPR1 FAXDC2 ABCC3 MACF1

1.45e-041983144397_DN
DrugPrilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A

CLSTN3 ALK SVEP1 MARCHF6

1.48e-041993144749_UP
DrugClobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A

VIPR1 CLSTN3 IFFO1 MARCHF6

1.51e-042003146095_UP
Drug6-thioguanine; Up 200; 10uM; MCF7; HG-U133A

VIPR1 HERPUD1 ALK INPP5K

1.51e-04200314642_UP
Drugtetramethylrosamine

ABCC3 ABCC6

1.62e-0414312CID000443313
DrugMX-68

ABCC3 ABCC6

1.86e-0415312CID006918310
DrugPAK-104P

ABCC3 ABCC6

1.86e-0415312CID000131368
Diseaselevel of Phosphatidylcholine (18:0_18:2) in blood serum

HERPUD1 ALG14

1.19e-0416302OBA_2045090
Diseaseblood pressure

VPS37A MYO16

2.28e-0422302EFO_0004325
Diseaselysophosphatidylcholine measurement

HERPUD1 ALG14

1.82e-0362302EFO_0010224
Diseasedentures

NEO1 ALK

2.31e-0370302EFO_0010078
Diseasedental caries, dentures

NEO1 ALK

2.31e-0370302EFO_0003819, EFO_0010078
Diseasenucleotide measurement

VIPR1 ALK

2.51e-0373302EFO_0010513
Diseasebipolar disorder

VIPR1 STARD9 ALG14 SVEP1

2.65e-03577304MONDO_0004985
Diseasephosphatidylcholine measurement

MACF1 HERPUD1 ALG14

2.96e-03284303EFO_0010226

Protein segments in the cluster

PeptideGeneStartEntry
IWFGHFTTSTILSPS

TMEM62

226

Q0P6H9
PQDSLSDHFTLSFWM

CLSTN3

366

Q9BQT9
STMVSTSAFPWEEFT

VCAN

1991

P13611
ETGSSFMSFWPHLQS

LINC00518

6

Q8N0U6
MESFHTRFSAWTPFS

ECT2L

1

Q008S8
PSTVFTTLHSMWLSF

ALG14

116

Q96F25
QTSPSFMSTAWLVFK

HERPUD1

361

Q15011
LHTTTTFTWMCSPFL

ABCC3

531

O15438
SIWSPSLHSVFSMDD

MYO16

1271

Q9Y6X6
SSFFLRTWLMTPLHI

HARBI1

226

Q96MB7
LSFQSAPGTTMFLHW

MARCHF6

411

O60337
AVIWTMATFFSLPHA

GPR83

191

Q9NYM4
ATHSSSTSWFRKPMT

MACF1

556

Q9UPN3
SSSARFMPGTIWSFS

IFFO1

186

Q0D2I5
GSHLSSITMWFSLAL

FAXDC2

241

Q96IV6
TVMNAAPFLSTTWFS

SLC49A4

161

Q96SL1
SWSSFLMDVLSPLSF

INPP5K

71

Q9BT40
PWVRSSHSMTMTFLV

SLC17A4

386

Q9Y2C5
TNHFSSWLATSLSMF

TAS2R30

91

P59541
IHPTVWLTTMSFAVF

ABCC6

106

O95255
YPEMSWTFLTSLIHS

NPHP3

791

Q7Z494
SHFTTPAPMSSAWKT

MYBL2

651

P10244
WPTKPSSMLSSVHFT

SLITRK3

306

O94933
WSMTAHGTTFELVPT

NEO1

941

Q92859
TMHFPSEAFSLSWHS

SHROOM4

116

Q9ULL8
STLSHMPTPDFTTSW

STARD9

3411

Q9P2P6
PSLHALTCTFWMKSS

SVEP1

1446

Q4LDE5
TWIMKDSFPFLSHRS

ALK

246

Q9UM73
PSTFTMVWTIARIHF

VIPR1

266

P32241
FSMSRSPAFTSWLST

STPG3

251

Q8N7X2
TEAMTHFPASPFWSV

SLC6A17

446

Q9H1V8
MSWLFPLTKSASSSA

VPS37A

1

Q8NEZ2