Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionkinase binding

CASS4 MYCN FLNA PDE3B PDE8A STUB1 GIT1 RPS6KA3 ITGB1BP1 PTPN23 DGKH JAKMIP3 TRIM6 HDAC7 TRIM5 FAF1 CASK CCNT2 PARP1 NELL2 CSPG4 DIXDC1 JAKMIP1

3.34e-0596918523GO:0019900
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RALGAPA1 RGPD2 ARHGEF28 GIT1 RASGRF2 ITGB1BP1 NUCB1 GIT2 TBC1D24 ARFGEF3 ARHGDIG DENND10 TBC1D22A RAB3GAP2 WDR41

7.98e-0550718515GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RALGAPA1 RGPD2 ARHGEF28 GIT1 RASGRF2 ITGB1BP1 NUCB1 GIT2 TBC1D24 ARFGEF3 ARHGDIG DENND10 TBC1D22A RAB3GAP2 WDR41

7.98e-0550718515GO:0030695
GeneOntologyMolecularFunctionNADH oxidase H202-forming activity

DUOX2 DUOX1

8.54e-0521852GO:0106293
GeneOntologyMolecularFunction3',5'-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity

PDE3A PDE3B

8.54e-0521852GO:0004119
GeneOntologyMolecularFunctionprotein homodimerization activity

FLNA AOC1 STUB1 GBP7 ACOX1 TRPC6 MYOM3 DGKH RNF40 TRIM6 TENM2 TRIM5 PARP1 GBP4 TBC1D22A MIGA1 CEP131 ABCD2

5.90e-0481518518GO:0042803
GeneOntologyMolecularFunctionpyrophosphatase activity

NUDT18 GBP6 DDX49 GBP7 DDX42 NUDT2 MCM2 ARL9 ATP9B ATP6V1H MDN1 GBP4 RECQL5 DDX43 ABCD2 DNAH5 DNAH9 SNRNP200

8.24e-0483918518GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

NUDT18 GBP6 DDX49 GBP7 DDX42 NUDT2 MCM2 ARL9 ATP9B ATP6V1H MDN1 GBP4 RECQL5 DDX43 ABCD2 DNAH5 DNAH9 SNRNP200

8.35e-0484018518GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

NUDT18 GBP6 DDX49 GBP7 DDX42 NUDT2 MCM2 ARL9 ATP9B ATP6V1H MDN1 GBP4 RECQL5 DDX43 ABCD2 DNAH5 DNAH9 SNRNP200

8.35e-0484018518GO:0016818
GeneOntologyMolecularFunctionferric-chelate reductase (NADPH) activity

STEAP4 STEAP3

8.38e-0451852GO:0052851
GeneOntologyMolecularFunctionferric-chelate reductase activity

STEAP4 STEAP3

8.38e-0451852GO:0000293
GeneOntologyMolecularFunctioncupric reductase (NADH) activity

STEAP4 STEAP3

8.38e-0451852GO:0008823
GeneOntologyMolecularFunctionNADPH oxidase H202-forming activity

DUOX2 DUOX1

8.38e-0451852GO:0106294
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX49 DDX42 MCM2 ATP9B ATP6V1H MDN1 RECQL5 DDX43 ABCD2 DNAH5 DNAH9 SNRNP200

8.69e-0444118512GO:0016887
GeneOntologyMolecularFunction3',5'-cyclic-AMP phosphodiesterase activity

PDE3A PDE3B PDE8A

1.06e-03221853GO:0004115
GeneOntologyMolecularFunction3',5'-cyclic-GMP phosphodiesterase activity

PDE3A PDE3B PDE8A

1.37e-03241853GO:0047555
GeneOntologyMolecularFunction3',5'-cyclic-nucleotide phosphodiesterase activity

PDE3A PDE3B PDE8A

1.55e-03251853GO:0004114
GeneOntologyMolecularFunction1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

PIK3R6 PIK3C2A

1.74e-0371852GO:0046934
GeneOntologyMolecularFunctionoxidoreductase activity, acting on metal ions, NAD or NADP as acceptor

STEAP4 STEAP3

1.74e-0371852GO:0016723
GeneOntologyCellularComponenthost intracellular region

GBP6 GBP7 GBP4

1.29e-0561833GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP6 GBP7 GBP4

1.29e-0561833GO:0030430
GeneOntologyCellularComponenthost cell part

GBP6 GBP7 GBP4

1.29e-0561833GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP6 GBP7 GBP4

1.29e-0561833GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP6 GBP7 GBP4

1.29e-0561833GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP6 GBP7 GBP4

1.29e-0561833GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP6 GBP7 GBP4

1.29e-0561833GO:0020005
GeneOntologyCellularComponentextrinsic component of membrane

ATR APC2 NUCB1 ZFYVE1 TENM2 CDH22 ATP6V1H PIK3R6 PIK3C2A

2.01e-042301839GO:0019898
GeneOntologyCellularComponenthost cellular component

GBP6 GBP7 GBP4

2.78e-04151833GO:0018995
GeneOntologyCellularComponentvesicle tethering complex

TRAPPC11 VPS18 VPS54 VIPAS39 COG4

4.24e-04721835GO:0099023
GeneOntologyCellularComponentextrinsic component of organelle membrane

ATR NUCB1 ZFYVE1 ATP6V1H

5.37e-04431834GO:0031312
GeneOntologyCellularComponentomegasome

ZFYVE1 TRIM5

7.49e-0451832GO:1990462
GeneOntologyCellularComponentaxonemal dynein complex

DNAH5 CCDC65 DNAH9

1.32e-03251833GO:0005858
HumanPhenoCone-shaped epiphyses of the phalanges of the hand

FLNA DYM ATR TRPS1 COG4

2.37e-0531595HP:0010230
HumanPhenoAbnormal limb epiphysis morphology

FLNA DYM ATR RPS6KA3 TRPS1 DUOX2 PIK3C2A RAB3GAP2 COG4

2.41e-05138599HP:0006505
HumanPhenoPhalangeal cone-shaped epiphyses

FLNA DYM ATR TRPS1 COG4

2.78e-0532595HP:0034281
HumanPhenoCone-shaped epiphysis

FLNA PDE3A DYM ATR TRPS1 TTC21B COG4

3.76e-0582597HP:0010579
HumanPhenoAbnormal hand epiphysis morphology

FLNA DYM ATR RPS6KA3 TRPS1 COG4

5.22e-0559596HP:0005924
HumanPhenoAbnormal upper limb epiphysis morphology

FLNA DYM ATR RPS6KA3 TRPS1 COG4

8.30e-0564596HP:0003839
HumanPhenoAbnormal epiphysis morphology of the phalanges of the hand

FLNA DYM ATR TRPS1 COG4

1.08e-0442595HP:0005920
HumanPhenoHypoplasia of proximal fibula

ATR COG4

1.32e-042592HP:0006442
HumanPhenoAbnormal tricuspid chordae tendinae morphology

FLNA RPS6KA3

1.32e-042592HP:0031442
HumanPhenoShort chordae tendineae of the tricuspid valve

FLNA RPS6KA3

1.32e-042592HP:0006692
HumanPhenoShort chordae tendineae of the mitral valve

FLNA RPS6KA3

1.32e-042592HP:0011580
DomainFerric_reduct

STEAP4 DUOX2 DUOX1 STEAP3

4.15e-06121834PF01794
DomainFe3_Rdtase_TM_dom

STEAP4 DUOX2 DUOX1 STEAP3

4.15e-06121834IPR013130
DomainPLAC

ADAMTS3 ADAMTS6 PCSK6 ADAMTS14

3.08e-05191834PS50900
DomainPLAC

ADAMTS3 ADAMTS6 PCSK6 ADAMTS14

3.08e-05191834IPR010909
DomainGIT

GIT1 GIT2

9.55e-0521832SM00555
DomainGIT1_C

GIT1 GIT2

9.55e-0521832PF12205
DomainGIT1/2_CC

GIT1 GIT2

9.55e-0521832IPR032352
DomainDUOX1

DUOX2 DUOX1

9.55e-0521832IPR029595
DomainGIT_SHD

GIT1 GIT2

9.55e-0521832PF08518
DomainGIT_CC

GIT1 GIT2

9.55e-0521832PF16559
DomainGIT1_C

GIT1 GIT2

9.55e-0521832IPR022018
DomainGIT_SHD

GIT1 GIT2

9.55e-0521832IPR013724
DomainGBP_C

GBP6 GBP7 GBP4

1.06e-04101833PF02841
DomainG_GB1_RHD3_dom

GBP6 GBP7 GBP4

1.44e-04111833IPR030386
DomainGuanylate-bd_N

GBP6 GBP7 GBP4

1.44e-04111833IPR015894
DomainGuanylate-bd_C

GBP6 GBP7 GBP4

1.44e-04111833IPR003191
DomainGBP

GBP6 GBP7 GBP4

1.44e-04111833PF02263
DomainG_GB1_RHD3

GBP6 GBP7 GBP4

1.44e-04111833PS51715
Domain-

TANC2 RGPD2 ATR STUB1 NAPG NASP TTC23 ASPH TTC21B

2.09e-0420718391.25.40.10
DomainTPR_REGION

TANC2 RGPD2 STUB1 NASP PTPN23 TTC23 ASPH TTC21B

2.26e-041651838PS50293
DomainTPR

TANC2 RGPD2 STUB1 NASP PTPN23 TTC23 ASPH TTC21B

2.26e-041651838PS50005
DomainTPR

TANC2 RGPD2 STUB1 NASP TTC23 ASPH TTC21B

2.83e-041291837SM00028
DomainJAKMIP_C

JAKMIP3 JAKMIP1

2.85e-0431832IPR031994
DomainJAKMIP_CC3

JAKMIP3 JAKMIP1

2.85e-0431832PF16034
DomainJAKMIP

JAKMIP3 JAKMIP1

2.85e-0431832IPR024836
DomainATPase_dyneun-rel_AAA

MDN1 DNAH5 DNAH9

3.11e-04141833IPR011704
DomainAAA_5

MDN1 DNAH5 DNAH9

3.11e-04141833PF07728
DomainTPR_repeat

TANC2 RGPD2 STUB1 NASP TTC23 ASPH TTC21B

3.41e-041331837IPR019734
DomaintRNAsynth_Ia_anticodon-bd

VARS2 RARS2 CEP131

3.86e-04151833IPR009080
DomainTPR-like_helical_dom

TANC2 RGPD2 ATR STUB1 NAPG NASP TTC23 ASPH TTC21B

4.98e-042331839IPR011990
DomainLaminin_G_2

NELL2 CELSR1 FAT2 CSPG4

6.19e-04401834PF02210
DomainP-loop_NTPase

TANC2 GBP6 DDX49 GBP7 DDX42 MCM2 ARL9 ZFYVE1 CASK MDN1 LRRIQ1 GBP4 RECQL5 DDX43 ABCD2 DNAH5 DNAH9 SNRNP200 NLRP13

6.81e-0484818319IPR027417
DomainTPR-contain_dom

TANC2 RGPD2 STUB1 NASP PTPN23 ASPH TTC21B

7.01e-041501837IPR013026
DomainDEAD/DEAH_box_helicase_dom

DDX49 DDX42 RECQL5 DDX43 SNRNP200

7.49e-04731835IPR011545
DomainDEAD

DDX49 DDX42 RECQL5 DDX43 SNRNP200

7.49e-04731835PF00270
DomainLamG

NELL2 CELSR1 FAT2 CSPG4

8.92e-04441834SM00282
DomainPyrv_Knase-like_insert_dom

PKLR MOCOS

9.36e-0451832IPR011037
DomainPDEase_I

PDE3A PDE3B PDE8A

1.08e-03211833PF00233
DomainPDEASE_I

PDE3A PDE3B PDE8A

1.08e-03211833PS00126
DomainPDEase_CS

PDE3A PDE3B PDE8A

1.08e-03211833IPR023174
Domain-

GBP6 DDX49 GBP7 DDX42 MCM2 ARL9 ZFYVE1 CASK MDN1 GBP4 RECQL5 DDX43 ABCD2 DNAH5 DNAH9 SNRNP200 NLRP13

1.09e-03746183173.40.50.300
Domain-

PDE3A PDE3B PDE8A

1.24e-032218331.10.1300.10
DomainADAM_spacer1

ADAMTS3 ADAMTS6 ADAMTS14

1.42e-03231833IPR010294
DomainADAM_spacer1

ADAMTS3 ADAMTS6 ADAMTS14

1.42e-03231833PF05986
DomainPDEase_catalytic_dom

PDE3A PDE3B PDE8A

1.42e-03231833IPR002073
DomainHD/PDEase_dom

PDE3A PDE3B PDE8A

1.61e-03241833IPR003607
DomainPeptidase_M12B_ADAM-TS

ADAMTS3 ADAMTS6 ADAMTS14

1.61e-03241833IPR013273
DomainHDc

PDE3A PDE3B PDE8A

1.61e-03241833SM00471
DomainARM-type_fold

RALGAPA1 ATR APC2 SCYL3 ARFGEF3 ATP6V1H PPP2R5D CSE1L PIK3C2A PUM3

1.93e-0333918310IPR016024
DomainProC_N

STEAP4 STEAP3

1.94e-0371832IPR028939
DomainNAD_binding_6

DUOX2 DUOX1

1.94e-0371832PF08030
DomainF420_oxidored

STEAP4 STEAP3

1.94e-0371832PF03807
DomainFAD_binding_8

DUOX2 DUOX1

1.94e-0371832PF08022
DomainFAD-bd_8

DUOX2 DUOX1

1.94e-0371832IPR013112
DomainFe_red_NAD-bd_6

DUOX2 DUOX1

1.94e-0371832IPR013121
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 RGPD2 NEDD4L GIT1 APC2 SRPK2 GIT2 SPECC1L JAKMIP3 ADNP TENM2 CASK PARP1 PPP2R5D MDN1 CEP131 TNKS DIXDC1 JAKMIP1 WDR1 GOLGA1

7.68e-089631892128671696
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RALGAPA1 KBTBD3 PDE3B DYM NEDD4L MAOA APMAP TRPS1 DAB1 SRPK2 ATP9B DGKH VPS54 FAF1 CASK SHISA9 ARFGEF3 ZNF544 TSPAN10 TBC1D22A ASPH TTC21B SPACA6 SEMA6A GLIS1 MOCOS

1.62e-0714891892628611215
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 RALGAPA1 PDE3B ARHGEF28 NEDD4L GIT1 RTCB ANKRD26 HDAC7 CDR2L ARFGEF3 FSIP2 RADIL MDN1 PIK3C2A RAB3GAP2 SRPK3 CEP131

1.25e-068611891836931259
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

FAM184B FLNA CTNNAL1 AOC1 DDX49 GBP7 INPP5B RPS6KA3 DDX42 NASP PTPN23 ZFYVE1 ASH2L TRIM5 MEST GBP4 FAM32A BIN2 TSTD2 COG4

2.13e-0610841892011544199
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

STUB1 GIT1 APC2 TRPS1 NUCB1 NASP SRPK2 NCKAP5 RNF40 VPS54 JAKMIP3 TRIM5 FAF1 CASK PARP1 NELL2 PCSK6 MIGA1 TNKS JAKMIP1 SNRNP200 COG4

2.17e-0612851892235914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TANC2 VPS18 ARHGEF28 ANKRD26 PTPN23 CC2D1B VARS2 RADIL FAT2 TTC21B PUM3 FHDC1 SNRNP200

3.43e-064931891315368895
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

TRAPPC11 VPS18 INPP5B SCYL3 VPS54 VIPAS39 PPP2R5D MB21D2 PIK3C2A STEAP3

4.05e-062851891034369648
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

FLNA PDE3A CDR2L PARP1 FAT2 MDN1 KIAA1549L DNAH5 SNRNP200

5.93e-06234189936243803
Pubmed

In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters.

GBP6 GBP7 GBP4

8.67e-068189316689661
Pubmed

HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway.

PDE3A PDE3B PDE8A PIK3C2A

1.34e-0527189411156964
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RALGAPA1 FAM184B PDE3B STUB1 NUCB1 DDX42 ANKRD26 SRPK2 VARS2 CASK PARP1 PPP2R5D MDN1 PIK3C2A RAB3GAP2 NIP7 ASPH STEAP3 CEP131 SEMA6A WDR41 SNRNP200

2.13e-0514871892233957083
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYCN FLNA ATR STUB1 GIT1 NASP MCM2 REST HDAC7 CCNT2 SH2D4A MDN1 ASPH SNRNP200 MOCOS

2.41e-057741891515302935
Pubmed

Extensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defense.

GBP6 GBP7 GBP4

2.52e-0511189318025219
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

ATR STUB1 RNF40 CSE1L PUM3 RARS2 SRPK3 CEP131 COG4

2.84e-05285189932838362
Pubmed

Digenic DUOX1 and DUOX2 Mutations in Cases With Congenital Hypothyroidism.

DUOX2 DUOX1

2.94e-052189228633507
Pubmed

Genetic Complexity of Crohn's Disease in Two Large Ashkenazi Jewish Families.

DUOX2 CSF2RB

2.94e-052189227373512
Pubmed

The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphatase.

GBP7 GBP4

2.94e-052189221142871
Pubmed

Presynaptic Deletion of GIT Proteins Results in Increased Synaptic Strength at a Mammalian Central Synapse.

GIT1 GIT2

2.94e-052189226637799
Pubmed

FAF1 mediates regulated necrosis through PARP1 activation upon oxidative stress leading to dopaminergic neurodegeneration.

FAF1 PARP1

2.94e-052189227662363
Pubmed

Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells.

DUOX2 DUOX1

2.94e-052189222523549
Pubmed

Expression of dual oxidases and secreted cytokines in chronic rhinosinusitis.

DUOX2 DUOX1

2.94e-052189223281318
Pubmed

Protection of telomeres 1 proteins POT1a and POT1b can repress ATR signaling by RPA exclusion, but binding to CST limits ATR repression by POT1b.

ATR POT1

2.94e-052189230082315
Pubmed

Dual oxidase 1 and NADPH oxidase 2 exert favorable effects in cervical cancer patients by activating immune response.

DUOX2 DUOX1

2.94e-052189231706280
Pubmed

A pathophysiological role of PDE3 in allergic airway inflammation.

PDE3A PDE3B

2.94e-052189229367458
Pubmed

The multifunctional GIT family of proteins.

GIT1 GIT2

2.94e-052189216598076
Pubmed

Tripartite motif-containing protein 6 facilitates growth and migration of breast cancer through degradation of STUB1.

STUB1 TRIM6

2.94e-052189233728863
Pubmed

Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.

DUOX2 DUOX1

2.94e-052189215972824
Pubmed

Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.

DUOX2 DUOX1

2.94e-052189223362256
Pubmed

Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation.

DUOX2 DUOX1

2.94e-052189219144650
Pubmed

Expression of nicotinamide adenine dinucleotide phosphate oxidase flavoprotein DUOX genes and proteins in human papillary and follicular thyroid carcinomas.

DUOX2 DUOX1

2.94e-052189211762710
Pubmed

Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.

DUOX2 DUOX1

2.94e-052189211822874
Pubmed

Role of phosphodiesterase type 3A and 3B in regulating platelet and cardiac function using subtype-selective knockout mice.

PDE3A PDE3B

2.94e-052189217482796
Pubmed

Dual oxidase 1 and 2 expression in airway epithelium of smokers and patients with mild/moderate chronic obstructive pulmonary disease.

DUOX2 DUOX1

2.94e-052189218177232
Pubmed

Targeted disruption of PDE3B, but not PDE3A, protects murine heart from ischemia/reperfusion injury.

PDE3A PDE3B

2.94e-052189225877153
Pubmed

Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis.

GBP7 GBP4

2.94e-052189237621179
Pubmed

Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.

DUOX2 DUOX1

2.94e-052189212824283
Pubmed

Phosphodiesterase type 3A (PDE3A), but not type 3B (PDE3B), contributes to the adverse cardiac remodeling induced by pressure overload.

PDE3A PDE3B

2.94e-052189231051182
Pubmed

Congenital Hypothyroidism due to Oligogenic Mutations in Two Sudanese Families.

DUOX2 DUOX1

2.94e-052189230375286
Pubmed

Whole-exome sequencing in adult patients with developmental and epileptic encephalopathy: It is never too late.

APC2 RARS2

2.94e-052189232725632
Pubmed

Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues.

GIT1 GIT2

2.94e-052189217565117
Pubmed

Pde3a and Pde3b regulation of murine pulmonary artery smooth muscle cell growth and metabolism.

PDE3A PDE3B

2.94e-052189239435735
Pubmed

Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

DUOX2 DUOX1

2.94e-052189210806195
Pubmed

Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.

DUOX2 DUOX1

2.94e-052189211514595
Pubmed

Roles of DUOX-mediated hydrogen peroxide in metabolism, host defense, and signaling.

DUOX2 DUOX1

2.94e-052189224161126
Pubmed

Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.

CSF2RB RORC

2.94e-052189224562309
Pubmed

Expression of reduced nicotinamide adenine dinucleotide phosphate oxidase (ThoX, LNOX, Duox) genes and proteins in human thyroid tissues.

DUOX2 DUOX1

2.94e-052189211443211
Pubmed

Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cdnas.

DUOX2 DUOX1

2.94e-052189210601291
Pubmed

hPuf-A/KIAA0020 modulates PARP-1 cleavage upon genotoxic stress.

PARP1 PUM3

2.94e-052189221266351
Pubmed

Phosphodiesterase 3A (PDE3A) deletion suppresses proliferation of cultured murine vascular smooth muscle cells (VSMCs) via inhibition of mitogen-activated protein kinase (MAPK) signaling and alterations in critical cell cycle regulatory proteins.

PDE3A PDE3B

2.94e-052189221632535
Pubmed

The extracellular A-loop of dual oxidases affects the specificity of reactive oxygen species release.

DUOX2 DUOX1

2.94e-052189225586178
Pubmed

CHIP mediates down-regulation of nucleobindin-1 in preosteoblast cell line models.

STUB1 NUCB1

2.94e-052189227178152
Pubmed

Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium.

DUOX2 DUOX1

2.94e-052189216111680
Pubmed

Interaction between PARP-1 and ATR in mouse fibroblasts is blocked by PARP inhibition.

ATR PARP1

2.94e-052189218691676
Pubmed

Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases.

DUOX2 DUOX1

2.94e-052189211753072
Pubmed

Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer.

DUOX2 DUOX1

2.94e-052189218281478
Pubmed

Structural and functional characterization of the two human ThOX/Duox genes and their 5'-flanking regions.

DUOX2 DUOX1

2.94e-052189215062544
Pubmed

Regulated hydrogen peroxide production by Duox in human airway epithelial cells.

DUOX2 DUOX1

2.94e-052189215677770
Pubmed

Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection.

DUOX2 DUOX1

2.94e-052189224128054
Pubmed

Cloning, expression, and characterization of a novel guanylate-binding protein, GBP3 in murine erythroid progenitor cells.

GBP7 GBP4

2.94e-05218929659399
Pubmed

TRPC6 channels promote dendritic growth via the CaMKIV-CREB pathway.

CAMK4 TRPC6

2.94e-052189218559891
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

FLNA DYM STUB1 RTCB RPS6KA3 NAPG MCM2 SPECC1L ARFGEF3 PARP1 ATP6V1H CSE1L MDN1 PIK3C2A NIP7 ASPH PUM3 RARS2 WDR1 SNRNP200 COG4

4.09e-0514401892130833792
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

TANC2 ARHGEF28 GIT1 RASGRF2 INPP5B DDX42 NASP MCM2 GIT2 ASH2L CASK CCNT2 RADIL CSE1L TNKS WDR1

4.48e-059161891632203420
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

FLNA MAOA STUB1 RTCB NUCB1 DDX42 PTPN23 MCM2 RNF40 VARS2 ZFYVE1 ASH2L TBC1D22A RAB3GAP2 CSPG4 ASPH RARS2 NDUFAF6 ADAMTS14 SNRNP200 GOLGA1

4.56e-0514511892130550785
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

FLNA PDE3A STUB1 GIT1 RTCB RPS6KA3 NUCB1 NASP PTPN23 MCM2 CC2D1B SARNP FAF1 ATP6V1H PPP2R5D SH2D4A CSE1L RAB3GAP2 WDR1 FTO SNRNP200

4.74e-0514551892122863883
Pubmed

Inhibition of type 5 phosphodiesterase counteracts β2-adrenergic signalling in beating cardiomyocytes.

PDE3A PDE3B PDE8A

5.50e-0514189325852085
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

FLNA NASP MCM2 RNF40 PARP1 CSE1L PKLR

5.92e-05179189736261009
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

PDE3A RTCB NASP MCM2 PARP1 CSE1L MDN1 ASPH CEP131 WDR1

7.20e-053991891037536630
Pubmed

A human MAP kinase interactome.

FLNA NEDD4L PTPN23 NCKAP5 SPECC1L KRT23 SH2D4A CSE1L KIAA1549L SNRNP200 COG4

7.81e-054861891120936779
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

FLNA GIT1 GIT2 HDAC7 RADIL CSE1L JAKMIP1 SNRNP200

8.31e-05255189815324660
Pubmed

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia.

RTCB MCM2 RNF40 ADNP WDR1 SNRNP200

8.47e-05131189634551306
Pubmed

Targeting PKLR/MYCN/ROMO1 signaling suppresses neuroendocrine differentiation of castration-resistant prostate cancer.

MYCN PKLR

8.78e-053189236963289
Pubmed

Identification and characterization of two novel (neuro)endocrine long coiled-coil proteins.

JAKMIP3 JAKMIP1

8.78e-053189217572408
Pubmed

The Balpha and Bdelta regulatory subunits of PP2A are necessary for assembly of the CaMKIV.PP2A signaling complex.

CAMK4 PPP2R5D

8.78e-053189219538941
Pubmed

Molecular cloning and chromosomal assignment of the human homologue of the rat cGMP-inhibited phosphodiesterase 1 (PDE3A)--a gene involved in fat metabolism located at 11p 15.1.

PDE3A PDE3B

8.78e-05318928921398
Pubmed

Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.

ADAMTS3 ADAMTS14

8.78e-053189211741898
Pubmed

Liver X receptor alpha interferes with SREBP1c-mediated Abcd2 expression. Novel cross-talk in gene regulation.

NR1H3 ABCD2

8.78e-053189216249184
Pubmed

NADPH oxidase DUOX1 and DUOX2 but not NOX4 are independent predictors in hepatocellular carcinoma after hepatectomy.

DUOX2 DUOX1

8.78e-053189221915726
Pubmed

Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.

PARP1 RECQL5

8.78e-053189226391948
Pubmed

Liver X receptor (LXR) mediates negative regulation of mouse and human Th17 differentiation.

NR1H3 RORC

8.78e-053189221266776
Pubmed

Comprehensive Bioinformatic Analysis Genes Associated to the Prognosis of Liposarcoma.

MCM2 NIP7

8.78e-053189230317246
Pubmed

Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.

ATR POT1

8.78e-053189218936156
Pubmed

The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.

ADAMTS3 ADAMTS14

8.78e-053189225863161
Pubmed

NADPH oxidase-dependent acid production in airway epithelial cells.

DUOX2 DUOX1

8.78e-053189215210697
Pubmed

Mitotic phosphorylation of tankyrase, a PARP that promotes spindle assembly, by GSK3.

PARP1 TNKS

8.78e-053189217026964
Pubmed

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

DNAH5 DNAH9

8.78e-053189215750039
Pubmed

STAMPing at the crossroads of normal physiology and disease states.

STEAP4 STEAP3

8.78e-053189226911931
Pubmed

Role of nicotinamide adenine dinucleotide phosphate oxidase in mediating vesicant-induced interleukin-6 secretion in human airway epithelial cells.

DUOX2 DUOX1

8.78e-053189224164541
Pubmed

DUOX enzyme activity promotes AKT signalling in prostate cancer cells.

DUOX2 DUOX1

8.78e-053189223225414
Pubmed

GBP3 promotes glioblastoma resistance to temozolomide by enhancing DNA damage repair.

GBP7 GBP4

8.78e-053189235780181
Pubmed

Identification and analysis of axonemal dynein light chain 1 in primary ciliary dyskinesia patients.

DNAH5 DNAH9

8.78e-053189215845866
Pubmed

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.

PARP1 TNKS

8.78e-053189233361107
Pubmed

A Shld1-controlled POT1a provides support for repression of ATR signaling at telomeres through RPA exclusion.

ATR POT1

8.78e-053189221070964
Pubmed

ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells.

ATR PARP1

8.78e-053189226586427
Pubmed

GBP3 promotes glioma cell proliferation via SQSTM1/p62-ERK1/2 axis.

GBP7 GBP4

8.78e-053189229128363
Pubmed

Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation.

PDE3A PDE3B

8.78e-053189232949251
Pubmed

Association of duoxes with thyroid peroxidase and its regulation in thyrocytes.

DUOX2 DUOX1

8.78e-053189219952225
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

GIT1 RASGRF2 ITGB1BP1 MYOM3 ANKRD26 GIT2 ASH2L FAF1 PIK3C2A PUM3 TNKS

9.52e-054971891123414517
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

RALGAPA1 VPS18 PDE8A SCYL3 ARFGEF3 VIPAS39 TBC1D22A STEAP3 MIGA1 WDR41 COG4

1.08e-045041891134432599
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

RALGAPA1 STUB1 POT1 RNF40 CCNT2 CEP131 TNKS

1.08e-04197189720811636
Pubmed

Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.

ITGA11 RTCB TRIM6 TRIM5 CDH22 CEP131 JAKMIP1

1.15e-04199189723382691
Cytoband1p22.2

GBP6 GBP7 GBP4

2.09e-042818931p22.2
Cytoband22q13.3

CELSR1 TBC1D22A

2.50e-046189222q13.3
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TANC2 RGPD2 STUB1 NASP TTC23 TTC21B

1.23e-041151216769
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS3 ADAMTS6 ADAMTS14

2.62e-0419121350
GeneFamilyProteases, serine|STEAP family

STEAP4 STEAP3

4.38e-04512121324
GeneFamilyPhosphodiesterases

PDE3A PDE3B PDE8A

5.34e-04241213681
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND07-28-samps / Age Group, Lineage, Cell class and subclass

AOC1 ARHGEF28 CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

2.12e-1017418711f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCellPND07-28-samps-Epithelial-Epithelial-non_alveolar|PND07-28-samps / Age Group, Lineage, Cell class and subclass

AOC1 ARHGEF28 CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

2.26e-1017518711c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B SUSD4 CTNNAL1 SRPK2 NCKAP5 DGKH RNF125 PIK3R6 ADAMTS6 PCSK6 SEMA6A

6.40e-1019318711e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SUSD4 NEDD4L STEAP4 CHST9 STOX1 SHISA9 ARFGEF3 CELSR1 FCGBP DNAH5

5.57e-09182187103f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

GBP6 CAPSL CHST9 NELL2 LRRIQ1 CFAP206 CFAP74 CCDC65 KIAA2012 DNAH9

7.22e-09187187106fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-dn_T|Bac-SEP / Disease, condition lineage and cell class

CTNNAL1 LIX1L ZFYVE1 NELL2 DUOX1 FBXO24 SDR42E2 FTO ABCD2 CCDC65

1.31e-08199187104150a479b80596accf679b37aa9b0ac15cc132b2
ToppCellBiopsy_IPF-Epithelial|Biopsy_IPF / Sample group, Lineage and Cell type

NEDD4L CAPSL CHST9 ARFGEF3 DUOX1 CELSR1 LRRIQ1 DNAH5 DNAH9 LRRC23

1.37e-082001871076f1ac00b34d07057d8da03d276438b719b46b1d
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG FCGBP LRRIQ1 FHDC1 DNAH5 CCDC65 KIAA2012 LRRC23

5.26e-081731879a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCellP03-Epithelial-airway_epithelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

7.75e-0818118791ea21d860d4d7abab3e21e130a16d044006656ee
ToppCellP03-Epithelial-airway_epithelial_cell-club_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

7.75e-08181187960a91587c59029a34e7bec1255083337fe21b72a
ToppCell21-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

OTUD1 CAPSL LRRIQ1 PCSK6 FIBCD1 CFAP206 CCDC65 DNAH9 LRRC23

8.13e-0818218796e35892fa959ee31591850ded8f1088195ddeb01
ToppCellP28-Epithelial-airway_epithelial_cell-club_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

9.78e-081861879a26811481668fa25c48a064a56c198685693ad8d
ToppCellCiliated-cil-1|World / Class top

AOC1 CAPSL ARHGDIG CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

9.78e-081861879283de646a0e8a322c42a714ae19db9918011146e
ToppCellP28-Epithelial-airway_epithelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

9.78e-081861879df80f101954b8ec6ccdb03e702de22e70b65181f
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.02e-07187187904dba2ed09ee4180830bdf0191921696697ea234
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 FHDC1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.02e-0718718791bba994aaaa9825b54aaeaff3829850267bc4602
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.02e-071871879805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 FHDC1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.02e-071871879d6ac351e7aeba98851d308c14ac395044fe4fbbb
ToppCellCiliated|World / Class top

AOC1 CAPSL ARHGDIG CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.07e-071881879cc9178361360b5800f96516ed6a65089c144b1ce
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.12e-071891879057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.12e-071891879b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 LRRC23

1.12e-071891879fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCelldroplet-Lung-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 FHDC1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.12e-071891879a28e0922e10013ae79266f6a3f9305e6ee614d8b
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 LRRC23

1.12e-07189187938cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

SUSD4 ARHGEF28 NEDD4L STEAP4 CHST9 ARFGEF3 CELSR1 FAT2 DNAH5

1.12e-07189187984d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.12e-0718918799f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPSL CHST9 STOX1 LRRIQ1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.12e-071891879b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 LRRC23

1.12e-071891879565063f9e3dd79164321f8a394bd12c176baf202
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 LRRC23

1.12e-071891879497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.12e-0718918794e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCellCiliated|World / shred by cell class for parenchyma

CAPSL CHST9 STOX1 LRRIQ1 CFAP206 CFAP74 DNAH5 CCDC65 DNAH9

1.12e-071891879711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.12e-071891879e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.17e-0719018799ffd18ef358f8e32c610ab6420f479067c8ba44b
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.17e-0719018793ef39d61c98de4e5df946b995847aa65eba6a4b6
ToppCellfacs-Lung-nan-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.17e-071901879e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCellfacs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.17e-071901879fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.23e-071911879649fcb62ad15de2f83e61591e43923a717664ae7
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-0719118797b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-lung_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.23e-0719118799621e22e14ea069f22713947c9faa2d882abe5fe
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-0719118799f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CAPSL CHST9 ARFGEF3 DUOX1 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-0719118795129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class (2021.01.30)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879b78547dae8328244a47c83346447bdd787efbcae
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

CAPSL CHST9 STOX1 ARFGEF3 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-071911879cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.23e-0719118796a8fc9dc1a4c7115862e8f20204fa2f95e50e22f
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CAPSL CHST9 ARFGEF3 DUOX1 LRRIQ1 CFAP74 DNAH5 KIAA2012 DNAH9

1.23e-0719118796228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 LRRC23

1.23e-07191187996483adb97c81208aa513782550acd8a08b63866
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B SUSD4 CTNNAL1 SRPK2 NCKAP5 DGKH PIK3R6 ADAMTS6 SEMA6A

1.34e-0719318796e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE3B SUSD4 CTNNAL1 NEDD4L SRPK2 NCKAP5 DGKH CASK SEMA6A

1.34e-071931879e1d546165dcc2392f540162206852c4717d7306f
ToppCellmild_COVID-19_(asymptomatic)-CD4+_Tcm|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

PDE3B SUSD4 RASGRF2 CAMK4 CASK NELL2 MB21D2 RNF125 ZBTB25

1.34e-071931879498d3a83bce6deff69aea71b18a43688e0a8ed7d
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

CAPSL LRRIQ1 CFAP206 CFAP74 DIXDC1 DNAH5 KIAA2012 DNAH9 LRRC23

1.34e-071931879ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell15-Airway-Epithelial|Airway / Age, Tissue, Lineage and Cell class

SUSD4 NEDD4L CAPSL STEAP4 CHST9 ARFGEF3 CELSR1 LRRIQ1 DNAH5

1.46e-071951879cd0af7e260e4f0c5a9ecdfa93619f37b2a9308a5
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPSL CHST9 STOX1 LRRIQ1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.60e-07197187991637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPSL CHST9 STOX1 LRRIQ1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.60e-07197187922c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPSL CHST9 STOX1 LRRIQ1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.60e-0719718793bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPSL CHST9 STOX1 LRRIQ1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.60e-07197187987db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CAPSL CHST9 STOX1 LRRIQ1 CFAP206 CFAP74 DNAH5 KIAA2012 DNAH9

1.74e-0719918792de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCelldistal-Epithelial-Ciliated|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CAPSL CHST9 STOX1 LRRIQ1 CFAP206 DNAH5 CCDC65 DNAH9 LRRC23

1.74e-07199187918ca031cfe702afb9bf94e03c0f3680c38e7599e
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.74e-07199187915f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCelldistal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CAPSL CHST9 STOX1 LRRIQ1 CFAP206 DNAH5 CCDC65 DNAH9 LRRC23

1.74e-0719918797e5f29f4ec1fea92f2c0064eea151d2d474ef904
ToppCelldistal-Epithelial-Ciliated-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CAPSL CHST9 STOX1 LRRIQ1 CFAP206 DNAH5 CCDC65 DNAH9 LRRC23

1.74e-0719918796ce0df4a6f4d9353919e26ffab97c9ec89911da6
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CAPSL CHST9 KRT23 LRRIQ1 CFAP206 DNAH5 CCDC65 DNAH9 LRRC23

1.81e-072001879cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CAPSL CHST9 STOX1 LRRIQ1 CFAP74 DNAH5 CCDC65 KIAA2012 DNAH9

1.81e-07200187985c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CAPSL DUOX2 CHST9 KRT23 LRRIQ1 DNAH5 CCDC65 DNAH9 LRRC23

1.81e-072001879da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CAPSL CHST9 KRT23 LRRIQ1 CFAP206 DNAH5 CCDC65 DNAH9 LRRC23

1.81e-072001879a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPSL CHST9 STOX1 LRRIQ1 CFAP74 DNAH5 CCDC65 DNAH9 LRRC23

1.81e-072001879f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CAPSL CHST9 STOX1 LRRIQ1 CFAP74 DNAH5 CCDC65 DNAH9 LRRC23

1.81e-072001879d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CAPSL CHST9 STOX1 LRRIQ1 CFAP74 DNAH5 CCDC65 KIAA2012 DNAH9

1.81e-07200187912bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPSL CHST9 STOX1 LRRIQ1 CFAP74 DNAH5 CCDC65 DNAH9 LRRC23

1.81e-072001879cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CAPSL DUOX2 CHST9 KRT23 LRRIQ1 DNAH5 CCDC65 DNAH9 LRRC23

1.81e-07200187972c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellBac-SEP-Lymphocyte-T_NK-dnT|Bac-SEP / Disease, Lineage and Cell Type

CTNNAL1 LIX1L ZFYVE1 NELL2 FBXO24 SDR42E2 FTO ABCD2

3.99e-071601878f5ca49801c981b903a85a64b21ece6b59fe91cbc
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGDIG LRRIQ1 FHDC1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

8.57e-071771878d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGDIG LRRIQ1 FHDC1 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

8.57e-071771878d5640f0097878f0dac671e51dc51310278bb2682
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B RASGRF2 CAMK4 NELL2 RNF125 ADAMTS6 SDR42E2 LRRC23

8.95e-07178187831c847d7f7aa0f6d820afbb45d507992f5e9dc2f
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

SUSD4 ARHGEF28 STEAP4 CHST9 SHISA9 ARFGEF3 CELSR1 FCGBP

9.33e-0717918781fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 PKLR DNAH5 CCDC65 DNAH9 LRRC23

9.33e-071791878d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPSL ARHGDIG LRRIQ1 PKLR DNAH5 CCDC65 DNAH9 LRRC23

9.33e-0717918788a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CYP2B6 SUSD4 NEDD4L STEAP4 NCKAP5 ARFGEF3 CELSR1 DNAH5

9.73e-071801878b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellEpithelial-lung_goblet_cell|World / Lineage, Cell type, age group and donor

SUSD4 ARHGEF28 STEAP4 CHST9 SHISA9 ARFGEF3 CELSR1 FCGBP

1.10e-061831878940cbe298e9c53b5622af09264586ed823d3141f
ToppCellPND07-28-samps-Epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ARHGEF28 CAPSL KRT23 ARFGEF3 LRRIQ1 CFAP206 DNAH5 LRRC23

1.10e-061831878a98f1d71d82ed6cca996f74352ab834fb6e95206
ToppCellfacs-Lung-EPCAM-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 DNAH9 LRRC23

1.15e-061841878afb11ab301ef9801333dbb53ccff4bd0d44f1677
ToppCellP07-Epithelial-airway_epithelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 KIAA2012 DNAH9 LRRC23

1.15e-061841878a5e7af3392e9d6ddad0397f1eeb6b91ed1107cc2
ToppCellP07-Epithelial-airway_epithelial_cell-club_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 KIAA2012 DNAH9 LRRC23

1.15e-061841878ab469b9e06212462cbe2e4db8775c6778db855e6
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 LRRIQ1 CFAP74 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.15e-061841878264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAPSL ARHGDIG LRRIQ1 CFAP206 DNAH5 CCDC65 DNAH9 LRRC23

1.15e-061841878a411c0bcb283534a1c15f22473c46b7d87e01294
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.15e-061841878797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 LRRIQ1 CFAP74 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.15e-061841878d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGA11 LRRIQ1 CFAP74 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.15e-06184187822010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.15e-06184187877d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

CYP2B6 SUSD4 NEDD4L STEAP4 ARFGEF3 DUOX1 CELSR1 DNAH5

1.20e-061851878cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CAPSL CHST9 LRRIQ1 CFAP206 CFAP74 DNAH5 KIAA2012 DNAH9

1.20e-061851878f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

CAPSL CHST9 LRRIQ1 CFAP206 CFAP74 DNAH5 KIAA2012 DNAH9

1.20e-06185187818a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CAPSL STOX1 LRRIQ1 CFAP206 CFAP74 DNAH5 CCDC65 DNAH9

1.24e-06186187876033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellPND14-Epithelial-Epithelial_Airway|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CAPSL LRRIQ1 CFAP206 DNAH5 CCDC65 KIAA2012 DNAH9 LRRC23

1.30e-0618718781399c703505211c510b3f14c7a2aa9930566c473
ToppCellCiliated-cil-2|World / Class top

AOC1 CAPSL ARHGDIG CFAP206 DNAH5 KIAA2012 DNAH9 LRRC23

1.30e-061871878e2e58ba039b5355c03c3b448e750aa37b0ea6913
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

DUOX2 DUOX1 DHH

1.83e-0591803DOID:0050338 (implicated_via_orthology)
DiseaseFG syndrome (is_implicated_in)

FLNA CASK

1.11e-0431802DOID:14711 (is_implicated_in)
DiseaseBilateral Periventricular Nodular Heterotopia

FLNA NEDD4L

1.11e-0431802C4551969
DiseaseFG SYNDROME 4 (disorder)

FLNA CASK

1.11e-0431802C1845546
DiseaseFG SYNDROME 2

FLNA CASK

1.11e-0431802C1845902
DiseasePeriventricular Heterotopia, X-Linked

FLNA NEDD4L

1.11e-0431802C1848213
DiseaseFG SYNDROME 3

FLNA CASK

1.11e-0431802C1845567
DiseaseFG syndrome

FLNA CASK

1.11e-0431802C0220769
DiseaseFEV/FEC ratio

PDE3A ARHGEF28 TRPS1 NAPG NASP REST FAF1 HAPLN1 SHISA9 NELL2 FCGBP TTC23 TSPAN10 CSPG4 MIGA1 WDR41 FTO DNAH5 LRRC23

1.94e-04122818019EFO_0004713
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA DYM TRPS1

2.01e-04191803DOID:2256 (is_implicated_in)
Diseasephenylketonuria (implicated_via_orthology)

DUOX2 DUOX1

2.20e-0441802DOID:9281 (implicated_via_orthology)
DiseaseFG syndrome

FLNA CASK

2.20e-0441802cv:C0220769
Diseasecortical surface area measurement

TANC2 ITGA11 PDE3A PDE8A ADAMTS3 DAB1 SRPK2 NCKAP5 REST STOX1 TENM2 PRPF18 FAF1 CELSR1 LRRIQ1 TBC1D22A RAB3GAP2 TNKS SEMA6A WDR1

2.21e-04134518020EFO_0010736
Diseaserelapsing-remitting multiple sclerosis (is_implicated_in)

CSPG4 ADAMTS14

3.66e-0451802DOID:2378 (is_implicated_in)
Diseaseperiventricular nodular heterotopia (is_implicated_in)

FLNA NEDD4L

5.46e-0461802DOID:0050454 (is_implicated_in)
DiseaseBone Diseases, Developmental

RPS6KA3 ITGB1BP1 TRPS1

5.86e-04271803C0005941
DiseasePeriventricular Nodular Heterotopia

FLNA NEDD4L

7.62e-0471802C1868720
Diseasecystatin C measurement

APMAP OTUD1 TBC1D24 PIK3C2A CSPG4 ZNF778 FTO KIAA2012 GLIS1

8.55e-044021809EFO_0004617
Diseasebody fat percentage

RALGAPA1 DYM AOC1 TRPS1 JAKMIP3 CSE1L TNKS WDR41 FTO KIAA2012

8.76e-0448818010EFO_0007800
DiseaseLarge cell carcinoma of lung

ATR CAMK4 CASK

9.72e-04321803C0345958
Diseasepneumococcal meningitis

CELSR1 TBC1D22A

1.01e-0381802EFO_1001114
DiseaseAlzheimer disease, survival time

NCKAP5 IL19

1.01e-0381802EFO_0000714, MONDO_0004975
Diseasemucocutaneous lymph node syndrome

DAB1 SPECC1L SARNP CDH22

1.22e-03761804EFO_0004246
DiseaseIntellectual Disability

TANC2 RALGAPA1 APC2 NUDT2 PTPN23 SPECC1L PARP1 PPP2R5D RNF125

1.78e-034471809C3714756
DiseaseBehavior Disorders

MAOA TRPC6

2.35e-03121802C0004930
DiseaseMental disorders

MAOA TRPC6

2.35e-03121802C0004936
Diseasestenosing tenosynovitis

ADAMTS6 FTO

2.35e-03121802EFO_0010822
DiseaseMental Disorders, Severe

MAOA TRPC6

2.35e-03121802C4046029
DiseaseDiagnosis, Psychiatric

MAOA TRPC6

2.35e-03121802C0376338
Diseasenevus count, cutaneous melanoma

NUDT18 POT1 PARP1 FTO

2.37e-03911804EFO_0000389, EFO_0004632
DiseaseNeurodevelopmental Disorders

TANC2 ADNP CASK PPP2R5D

2.56e-03931804C1535926
DiseaseCongenital pontocerebellar hypoplasia

CASK RARS2

2.76e-03131802C0266468
Diseasehypothyroidism (implicated_via_orthology)

DUOX2 DUOX1

2.76e-03131802DOID:1459 (implicated_via_orthology)
Diseasebiological sex

DAB1 SRPK2 TENM2 NIP7 SEMA6A FTO

2.96e-032301806PATO_0000047
Diseasecaudate nucleus measurement, functional brain measurement, response to reward

CELSR1 SH2D4A SPACA6

2.97e-03471803EFO_0007849, EFO_0008387, EFO_0008396
DiseasePrimary Ciliary Dyskinesia

DNAH5 CCDC65 DNAH9

2.97e-03471803C4551720
Diseasecongenital hypothyroidism (implicated_via_orthology)

DUOX2 DUOX1

3.21e-03141802DOID:0050328 (implicated_via_orthology)
Diseasenausea and vomiting of pregnancy severity measurement

TRPC6 SPECC1L

3.21e-03141802EFO_0009265
DiseaseSitus ambiguus

DNAH5 DNAH9

3.69e-03151802C0266642
Diseaseintracerebral hemorrhage

DAB1 TRIM5

4.20e-03161802EFO_0005669
DiseaseChromosome Aberrations

MYCN POT1

4.20e-03161802C0008625
DiseaseAutosome Abnormalities

MYCN POT1

4.20e-03161802C0004403
DiseaseMuscle hypotonia

RALGAPA1 NUDT2

4.74e-03171802C0026827
DiseaseFetal Alcohol Syndrome

REST ADNP

4.74e-03171802C0015923
Diseasespinal stenosis

PDE3A NASP

4.74e-03171802EFO_0007490
Diseasesphingosine 1-phosphate measurement

DAB1 FTO

5.31e-03181802EFO_0800185
DiseaseX-12063 measurement

NEDD4L PDE8A ANKRD26 DNAH5 IL19

5.78e-031861805EFO_0021283
Diseasep-tau:beta-amyloid 1-42 ratio measurement

DDX49 TBC1D22A

5.91e-03191802EFO_0007709
Diseaseapolipoprotein A 1 measurement

PDE3A PDE3B DYM AOC1 ARHGEF28 TRPS1 NR1H3 ZNF285 TRIM5 VIPAS39 PCSK6 NDUFAF6

6.05e-0384818012EFO_0004614
Diseaseneuroimaging measurement

CTNNAL1 PDE8A ADAMTS3 TRPS1 DAB1 NCKAP5 FAF1 HAPLN1 NELL2 CELSR1 CCM2 LRRIQ1 RAB3GAP2 WDR1

6.09e-03106918014EFO_0004346

Protein segments in the cluster

PeptideGeneStartEntry
ERYFHHVLLVASEGI

TTC21B

16

Q7Z4L5
DLIYVGVEHVHRDAE

ZNF280A

31

P59817
LVQHVIEDHERIGYQ

ADNP

236

Q9H2P0
TILHSYVHLNADELE

DENND10P1

211

Q6NSW5
HHRISLEYSELQDKV

RNF40

251

O75150
HHESLDNDVAREIRY

AKAP2

41

Q9Y2D5
DVRDHYIAAQVEQQH

CCNT2

451

O60583
DTLRHVNEQHAKVYE

CDR2L

71

Q86X02
INAYIGHSVEKHRET

CYP2B6

241

P20813
YLEANIDAIHRSTDH

CASS4

471

Q9NQ75
LDIRSGDEVHYHVTA

CSPG4

1156

Q6UVK1
TDQDLERILHNVHLY

ABCD2

576

Q9UBJ2
LRSEDYEQAAAHTHR

COG4

146

Q9H9E3
IEQASHHLRVYESVA

CEACAM21

131

Q3KPI0
VSYHQVDLERELEHK

DIXDC1

451

Q155Q3
LSEAEEQYAHALRSH

CCDC65

106

Q8IXS2
EAAYHITDIHEALAL

ARL9

131

Q6T311
FRSLLDEHHISYVID

SPECC1L

466

Q69YQ0
RFIYETEHHNGIAEL

PPP2R5D

286

Q14738
HSAEHGYVDVTIDIR

BTBD11

801

A6QL63
GHHELAERLVECQYE

GIT1

211

Q9Y2X7
GHHELAERLVEIQYE

GIT2

211

Q14161
DGLVATYISEVHEHD

APMAP

381

Q9HDC9
IHDIAAVSYVRDDAA

CCM2

136

Q9BSQ5
ERLHHDTDDVTYQVY

ASPH

246

Q12797
QLHAHYTIEGEEERV

CELSR1

266

Q9NYQ6
THLVHYRVDLDVAGT

AOC1

511

P19801
VESYHSRLAAAIHDR

ANKRD26

1006

Q9UPS8
YDVEIRLSHEHQAYR

NUDT2

101

P50583
LVDYDSARHHLEAVQ

BIN2

146

Q9UBW5
VDEIYHDESLGVHIN

ADAMTS14

291

Q8WXS8
GIAHHDNAVLITRYD

ADAMTS6

346

Q9UKP5
AVVEHTLADVLYHVE

ASH2L

601

Q9UBL3
YTNRVEFLEEHHRVL

CFAP206

91

Q8IYR0
YEAVVRHVEQVLQRH

PTPN23

1446

Q9H3S7
IREAVVYLAHTHDGA

PUM3

351

Q15397
THATTHNAYDLEVID

PARP1

821

P09874
RTVRLHIAESYHDAT

KBTBD3

356

Q8NAB2
NDRLASYLDHVHALE

KRT26

91

Q7Z3Y9
YENELALHHSVEADT

KRT26

176

Q7Z3Y9
VVNYEDLAAREHVLA

MCM2

231

P49736
AHARIHLRDYVIEDD

MCM2

776

P49736
LQVERLQHTYVEALH

NR1H3

376

Q13133
HDSLVYVLNRDRHTV

RADIL

261

Q96JH8
RVQLSEEASLHYIHS

ARHGEF28

231

Q8N1W1
SDNIIIETLNHEHYE

MAOA

251

P21397
ENDHQDLVSVHIYIT

DUOX1

1441

Q9NRD9
HHLQVSEDVVRRHYV

RAB3GAP2

1261

Q9H2M9
ARQEHHYQIDTKTIE

FHDC1

121

Q9C0D6
HRELREQTVHYIADH

OTUD1

336

Q5VV17
YEAESEEQFVHHIRV

REST

166

Q13127
LQTHDVVAHEVYSDE

CASK

441

O14936
VRINNHEHTDIQEYI

MDN1

1106

Q9NU22
HDQREYDDQRALEIH

MB21D2

46

Q8IYB1
HYSTLEEQRDHVIAS

GOLGA1

236

Q92805
HRYLELESSGHRNEV

NELL2

111

Q99435
AHDILHLVELAAQYR

NUDT18

156

Q6ZVK8
AVAYLHENGIVHRDL

CAMK4

151

Q16566
QAHTAEEVDLRVLDY

FUT4

256

P22083
HHDENLVDRSAVAVY

FTO

231

Q9C0B1
ATRVIHDNYDQLEVH

IL19

136

Q9UHD0
TVEYLHAQGVVHRDL

RPS6KA3

526

P51812
DRHSRYQLEDESAHL

ATP9B

36

O43861
ADYERRLQHLTSHEA

FAM184B

156

Q9ULE4
VEENDHQDLVSVHIY

DUOX2

1436

Q9NRD8
RDEEHHSDYEHVQNV

FSIP2

5666

Q5CZC0
INYDVARDIDTHTHR

DDX42

571

Q86XP3
TYRHGEIVHIECELN

F13B

291

P05160
IHLRYVDISENHLTD

LRRC23

91

Q53EV4
HSDQRVVYLEHVVVR

PCSK6

531

P29122
ELDYEAQQHFHVKVR

FAT2

2336

Q9NYQ8
DALHDVQFSTRYEHV

PIK3C2A

1016

O00443
AVLYNDRSVLENHHA

PDE3A

856

Q14432
AVLYNDRSVLENHHA

PDE3B

841

Q13370
AILYNDTAVLESHHA

PDE8A

616

O60658
RDVIYDIASQAHLHL

NDUFAF6

256

Q330K2
EIISHYEEELTQLRH

KRT23

331

Q9C075
ADIVQKVGRDYDVHH

KIAA2012

766

Q0VF49
IKAAEIRSVYHLHQE

JAKMIP3

181

Q5VZ66
RQEVLAHYSHRALDD

LIX1L

256

Q8IVB5
QHAIAREAEAAVYHR

PKLR

421

P30613
HQALEQLHYVTELAE

GBP4

151

Q96PP9
HQALEQLHYVTELTE

GBP6

136

Q6ZN66
HQALEQLHYVTELTE

GBP7

136

Q8N8V2
HDTVEQVRYRILAHF

MOCOS

91

Q96EN8
ADLRAAYQAHQDEVH

JAKMIP1

181

Q96N16
DVSAHVDILEYSHNV

KIAA1549L

866

Q6ZVL6
VHEFHLNDYRSVKDV

ITGA11

211

Q9UKX5
LYIHHAIDLATEEVS

DGKH

976

Q86XP1
ATRDLAQYDAAHHEE

NUCB1

161

Q02818
LEAHDRLLAETHYQL

NASP

576

P49321
ILSTEYRHAHERGDV

LRRIQ1

1206

Q96JM4
YETHEAAQKAVLDLH

PABPC5

246

Q96DU9
VLLSHIEAYVEHFTQ

SCYL3

356

Q8IZE3
VDLVRASEAHCHYVV

ACOX1

521

Q15067
LALHEHYVQQDVELR

APC2

1281

O95996
IEGHVHYLIQEATDE

ATR

2616

Q13535
NIVNEIYHDESLGVH

ADAMTS3

286

O15072
EHIDHTFEIQYRKDT

CSF2RB

366

P32927
AYTSHEHRERILELS

CTNNAL1

336

Q9UBT7
HEISYIAKDITDHRA

DAB1

111

O75553
ITIEDLREVYNAKHH

CAPSL

131

Q8WWF8
YLVVSLFTDDDRTHH

ARHGDIG

196

Q99819
EILYHVEERNSHHVY

DYM

381

Q7RTS9
YESRNHVHVSVKADN

DHH

176

O43323
DFNRHLDTLTEHYDI

FAM32A

91

Q9Y421
HAVVIHSDYAISVQA

FCGBP

106

Q9Y6R7
RDVDIIDHHDNTYTV

FLNA

921

P21333
EERRIHQESELHSYL

STUB1

151

Q9UNE7
VEHIQSFLHSDIRYE

ARFGEF3

1541

Q5TH69
HHEDLRLSQKAEEVY

CC2D1B

606

Q5T0F9
RECLYILSSHDIEQH

FBXO24

471

O75426
HALTTQAAYELHVDL

FIBCD1

321

Q8N539
VVNSHLAAHIEEYER

INPP5B

476

P32019
LVTQYDIHLVHAIEE

DDX49

351

Q9Y6V7
LVYSVLDGEHHFTVD

CDH22

206

Q9UJ99
EHVDHYSRTKAIADQ

SDR42E2

171

A6NKP2
YRDVVAALAEAQDIH

DNAH9

296

Q9NYC9
LQLHHYEDEVRGIVD

DNAH9

1411

Q9NYC9
AIYLHHDESVLTNVF

FAF1

376

Q9UNN5
ELQSVHSERHVLLYG

HDAC7

576

Q8WUI4
YEQQEELVRHIEKSH

GLIS1

206

Q8NBF1
TILHSYVHLNADELE

DENND10

211

Q8TCE6
LSDTEINYDERSHLH

SPACA6

66

W5XKT8
EHYEATIQRHLAFID

CEP131

621

Q9UPN4
HHYSIFEQASIVEAL

MEST

116

Q5EB52
LASRGLDVHDVTHVY

DDX43

546

Q9NXZ2
TIYEAIRTEISLHNH

CFAP74

931

Q9C0B2
YETLITIHVHQRDIF

DNAH5

1886

Q8TE73
VSTSDQYDVLHRHAL

ITGB1BP1

121

O14713
TEFIDYSIEQSHHAI

PBOV1

66

Q9GZY1
DHLSDNYTLDHDRAI

HAPLN1

16

P10915
NYTLDHDRAIHIQAE

HAPLN1

21

P10915
AELAEHREVRHTYSL

MIGA1

331

Q8NAN2
EDGVLVYHHAQDVIL

PHYHIPL

316

Q96FC7
DDLDLHVIYDVSHNI

RTCB

341

Q9Y3I0
VFLQYTHARLHSLEE

RARS2

461

Q5T160
VAVAVHPDDSRYTHL

VARS2

346

Q5ST30
VLAVAAHDVGEYVRH

ATP6V1H

406

Q9UI12
HRLQAYLEEHAEEEA

SARNP

36

P82979
YIEHLLTQLEEQHRS

NCKAP5

31

O14513
HFHSVDIQASEIVEY

RGPD2

631

P0DJD1
EAIHQASYADILIER

RASGRF2

126

O14827
IVVFHQADIGEYVRH

NIP7

161

Q9Y221
TLEHYFHAVVAALEQ

PIK3R6

221

Q5UE93
LTIDILVYDNHVHVA

POT1

216

Q9NUX5
ERDLNIVVHVQHYEN

SHISA9

206

B4DS77
IDQDLQAYILHRIHS

TANC2

606

Q9HCD6
HYGNRVTDLIHRESD

TENM2

56

Q9NT68
ADIYTEHAHQVVVAK

WDR1

51

O75083
IHETINATDEEIDHY

SIX6OS1

51

Q8N1H7
YSRDEDHIAHIVELL

SRPK3

471

Q9UPE1
QSHLFHTVSRIYVED

CHST9

196

Q7L1S5
EEGIRFLHADYLSHI

ZBTB25

96

P24278
VSRHLLSYLVVDEAH

RECQL5

146

O94762
VHLAVHAENFRSEIV

TBC1D24

331

Q9ULP9
HHTFLTEEVAREYQV

TRIM5

126

Q9C035
SVDELEDHITQLHEY

SWI5

186

Q1ZZU3
VDVLLFHYESVHESQ

TRPS1

626

Q9UHF7
LQAESIVVHTYAAHA

CSE1L

511

P55060
IVVHTYAAHALERLF

CSE1L

516

P55060
RVYLLNEHVKTHTEE

ZNF778

516

Q96MU6
YNLVHELRAHETNIL

TRAPPC11

251

Q7Z392
ERARYLQTIVQHHLE

RALGAPA1

1996

Q6GYQ0
RELYEDSLLDHCITH

RNF125

146

Q96EQ8
AHHLTEAIQYVVEFA

RORC

321

P51449
ATEYVHSLQAEEHQL

MYCN

426

P04198
EHLQHRESNAEYLAS

STEAP3

121

Q658P3
VLVHLHRNDYVAAER

NAPG

201

Q99747
TRDLYDTATHNVHEE

SAGE2P

381

A6NJ88
VLAQDVQYEHSHLEG

STOX1

911

Q6ZVD7
AARDHIYTVDIDTSH

SEMA6A

71

Q9H2E6
RVSVVEYLLHHGADV

TNKS

696

O95271
HEAYEEALAVLARHR

VPS18

576

Q9P253
DYSRDEDHIAHIIEL

SRPK2

591

P78362
QIEDAEIHNKTYRHG

SUSD4

126

Q5VX71
LQHATLADLVEYHKE

SH2D4A

411

Q9H788
IHREHYDFLTELTEV

STEAP4

81

Q687X5
SIHRHVATQHADEIY

TSTD2

91

Q5T7W7
EELALSHYREHLNIQ

VIPAS39

251

Q9H9C1
DSAHIQDHYTLLERQ

VIPAS39

286

Q9H9C1
EQVHRHLDQHEVRYL

TBC1D22A

401

Q8WUA7
DLVIYRTHADRLHND

ZFYVE1

261

Q9HBF4
FQIHERTHSEEKAYE

ZNF844

296

Q08AG5
NAAEYENIPIRHHED

SNRNP200

1851

O75643
SLEHTLRVAIAHYQD

TSPAN10

181

Q9H1Z9
KDRAREELSHHVEVY

ZNF544

96

Q6NX49
SNSHEYKQAVHELVR

TTC23

56

Q5W5X9
AAHCQEYEIVHTLLR

TRPC6

226

Q9Y210
HVAHVLNDETQRKYI

PRPF18

301

Q99633
LAHQRVHIDETQYTH

ZNF285

556

Q96NJ3
AHHDIVRFLVQLDDY

WDR41

41

Q9HAD4
LTRHQRTHSEEELYV

ZNF169

501

Q14929
RGHHTFLVEEVAQEY

TRIM6

126

Q9C030
HYLDIVEVNIAHQIS

VPS54

211

Q9P1Q0
HVYIRNTSKDEHEEL

NLRP13

201

Q86W25
NVHASEIREAYVVLA

MYOM3

506

Q5VTT5
ERIHLDGRTFYIDHN

NEDD4L

556

Q96PU5