Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine phosphatase activity	PTPRC PTPRD PTPRF	6.34e-05	17	93	3	GO:0005001
GeneOntologyMolecularFunction	transmembrane receptor protein phosphatase activity	PTPRC PTPRD PTPRF	6.34e-05	17	93	3	GO:0019198
GeneOntologyMolecularFunction	acid-amino acid ligase activity	TTLL9 TTL TTLL13	1.62e-04	23	93	3	GO:0016881
Domain	TTL	TTLL9 TTL TTLL13	2.99e-05	13	90	3	PS51221
Domain	TTL/TTLL_fam	TTLL9 TTL TTLL13	2.99e-05	13	90	3	IPR004344
Domain	TTL	TTLL9 TTL TTLL13	2.99e-05	13	90	3	PF03133
Domain	fn3	SDK2 PTPRC PTPRD PTPRF MYOM2 USH2A	1.32e-04	162	90	6	PF00041
Domain	FN3	SDK2 PTPRC PTPRD PTPRF MYOM2 USH2A	2.72e-04	185	90	6	SM00060
Domain	FN3	SDK2 PTPRC PTPRD PTPRF MYOM2 USH2A	4.02e-04	199	90	6	PS50853
Domain	ATP_grasp_subdomain_2	TTLL9 TTL TTLL13	4.41e-04	31	90	3	IPR013816
Domain	FN3_dom	SDK2 PTPRC PTPRD PTPRF MYOM2 USH2A	5.21e-04	209	90	6	IPR003961
Domain	PTPc	PTPRC PTPRD PTPRF	6.89e-04	36	90	3	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPRC PTPRD PTPRF	8.72e-04	39	90	3	PS50055
Domain	PTPase_domain	PTPRC PTPRD PTPRF	1.01e-03	41	90	3	IPR000242
Domain	Y_phosphatase	PTPRC PTPRD PTPRF	1.01e-03	41	90	3	PF00102
Domain	Ig_I-set	SDK2 PTPRD PTPRF CILP MYOM2	2.26e-03	190	90	5	IPR013098
Domain	I-set	SDK2 PTPRD PTPRF CILP MYOM2	2.26e-03	190	90	5	PF07679
Domain	PTPc_motif	PTPRC PTPRD PTPRF	2.89e-03	59	90	3	SM00404
Domain	Tyr_Pase_cat	PTPRC PTPRD PTPRF	2.89e-03	59	90	3	IPR003595
Domain	DUF1605	DHX16 DHX33	2.98e-03	17	90	2	IPR011709
Domain	OB_NTP_bind	DHX16 DHX33	2.98e-03	17	90	2	PF07717
Domain	HA2	DHX16 DHX33	3.34e-03	18	90	2	SM00847
Domain	HA2	DHX16 DHX33	3.34e-03	18	90	2	PF04408
Domain	Helicase-assoc_dom	DHX16 DHX33	3.34e-03	18	90	2	IPR007502
Domain	Fd_Rdtase_FAD-bd	DUOX2 NOS1	3.72e-03	19	90	2	IPR017927
Domain	BAR	ARHGEF38 ACAP2	3.72e-03	19	90	2	PS51021
Domain	FAD_FR	DUOX2 NOS1	3.72e-03	19	90	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	DUOX2 NOS1	3.72e-03	19	90	2	IPR017938
Domain	Tyr_Pase_AS	PTPRC PTPRD PTPRF	5.28e-03	73	90	3	IPR016130
Pubmed	Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.	PTPRC PTPRD PTPRF	7.08e-07	7	96	3	12376545
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MRPS31 DHX16 ATP6V1A RBM22 KIF23 POLR2A MRPS9 DUOX2 UPF3B GLOD4 CDC73 EMC8 NDUFA4 OLA1 HNRNPAB GOT2	1.74e-06	1425	96	16	30948266
Pubmed	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.	PTPRC PTPRD PTPRF	4.40e-06	12	96	3	9624153
Pubmed	The noncatalytic domains of Lck regulate its dephosphorylation by CD45.	PTPRC LCK	7.54e-06	2	96	2	12922168
Pubmed	Lateral compartmentalization of T cell receptor versus CD45 by galectin-N-glycan binding and microfilaments coordinate basal and activation signaling.	PTPRC LCK	7.54e-06	2	96	2	17897956
Pubmed	Beta-selection of immature thymocytes is less dependent on CD45 tyrosinephosphatase.	PTPRC LCK	7.54e-06	2	96	2	9870664
Pubmed	Nuclear lymphocyte-specific protein tyrosine kinase and its interaction with CR6-interacting factor 1 promote the survival of human leukemic T cells.	LCK GADD45GIP1	7.54e-06	2	96	2	25997448
Pubmed	CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.	PTPRC LCK	7.54e-06	2	96	2	9581568
Pubmed	Lymphocyte-specific protein tyrosine kinase (Lck) interacts with CR6-interacting factor 1 (CRIF1) in mitochondria to repress oxidative phosphorylation.	LCK GADD45GIP1	7.54e-06	2	96	2	26210498
Pubmed	An activated epidermal growth factor receptor/Lck chimera restores early T cell receptor-mediated calcium response in a CD45-deficient T cell line.	PTPRC LCK	7.54e-06	2	96	2	8663450
Pubmed	Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR.	PTPRC PTPRF	7.54e-06	2	96	2	1695146
Pubmed	Partial USH2A deletions contribute to Usher syndrome in Denmark.	PCDH15 USH2A	7.54e-06	2	96	2	25804404
Pubmed	Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development.	PTPRC LCK	7.54e-06	2	96	2	10330160
Pubmed	CD45RO regulates the HIV-1 gp120-mediated apoptosis of T cells by activating Lck.	PTPRC LCK	7.54e-06	2	96	2	29549706
Pubmed	Membrane-cytoskeleton interactions in cholesterol-dependent domain formation.	PTPRC LCK	7.54e-06	2	96	2	25658353
Pubmed	Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation.	PTPRC LCK	7.54e-06	2	96	2	15687496
Pubmed	Demonstration of a direct interaction between p56lck and the cytoplasmic domain of CD45 in vitro.	PTPRC LCK	7.54e-06	2	96	2	8576115
Pubmed	Differential requirements of CD45 protein tyrosine phosphatase for cytolytic activities and intrathymic and extrathymic development of intestinal intraepithelial lymphocytes.	PTPRC LCK	7.54e-06	2	96	2	9725213
Pubmed	The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.	PTPRD PTPRF	7.54e-06	2	96	2	7665159
Pubmed	Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions.	PTPRC LCK	7.54e-06	2	96	2	33225946
Pubmed	Lck-dependent tyrosine phosphorylation of diacylglycerol kinase alpha regulates its membrane association in T cells.	DGKA LCK	7.54e-06	2	96	2	18424699
Pubmed	GM1 controlled lateral segregation of tyrosine kinase Lck predispose T-cells to cell-derived galectin-1-induced apoptosis.	PTPRC LCK	7.54e-06	2	96	2	24231767
Pubmed	Phosphatase CD45 both positively and negatively regulates T cell receptor phosphorylation in reconstituted membrane protein clusters.	PTPRC LCK	7.54e-06	2	96	2	25128530
Pubmed	A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45.	PTPRC LCK	7.54e-06	2	96	2	28735895
Pubmed	Identification of intrinsic primary afferent neurons in mouse jejunum.	POLR2A NOS1	7.54e-06	2	96	2	32986284
Pubmed	Cutting edge: the CD45 tyrosine phosphatase is an inhibitor of Lck activity in thymocytes.	PTPRC LCK	7.54e-06	2	96	2	9973453
Pubmed	Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus.	PTPRC LCK	7.54e-06	2	96	2	15085197
Pubmed	An oncogenic tyrosine kinase inhibits DNA repair and DNA-damage-induced Bcl-xL deamidation in T cell transformation.	PTPRC LCK	7.54e-06	2	96	2	14749125
Pubmed	CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line.	PTPRC LCK	7.54e-06	2	96	2	8473339
Pubmed	Biochemical analysis of the CD45-p56(lck) complex in Jurkat T cells lacking expression of lymphocyte phosphatase-associated phosphoprotein.	PTPRC LCK	7.54e-06	2	96	2	9533446
Pubmed	CD44-initiated cell spreading induces Pyk2 phosphorylation, is mediated by Src family kinases, and is negatively regulated by CD45.	PTPRC LCK	7.54e-06	2	96	2	11369760
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	PTPRD ARHGEF38 PCDH15 NRG3 USH2A	9.27e-06	101	96	5	18519826
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	MRPS31 DMGDH VPS13D KIF23 ABCB7 TIMM21 POLG SELENOO MRPS9 GLOD4 NDUFA4 GADD45GIP1 GOT2	1.48e-05	1136	96	13	34800366
Pubmed	CD45 down-regulates Lck-mediated CD44 signaling and modulates actin rearrangement in T cells.	PTPRC LCK	2.26e-05	3	96	2	18981123
Pubmed	Regulation of Lck and Fyn tyrosine kinase activities by transmembrane protein tyrosine phosphatase leukocyte common antigen-related molecule.	PTPRF LCK	2.26e-05	3	96	2	12496362
Pubmed	Regulation of Ly49D/DAP12 signal transduction by Src-family kinases and CD45.	PTPRC LCK	2.26e-05	3	96	2	16709819
Pubmed	LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.	PTPRD PTPRF	2.26e-05	3	96	2	31985401
Pubmed	Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.	PTPRD PTPRF	2.26e-05	3	96	2	20139422
Pubmed	Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.	PTPRD PTPRF	2.26e-05	3	96	2	25703008
Pubmed	Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.	PTPRD PTPRF	2.26e-05	3	96	2	9784606
Pubmed	Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.	PTPRD PTPRF	2.26e-05	3	96	2	33656439
Pubmed	CD45 regulation of tyrosine phosphorylation and enzyme activity of src family kinases.	PTPRC LCK	2.26e-05	3	96	2	8175795
Pubmed	Genome-wide association study of copy number variations (CNVs) with opioid dependence.	PTPRC PTPRD	2.26e-05	3	96	2	25345593
Pubmed	T/B lineage choice occurs prior to intrathymic Notch signaling.	PTPRC DLL1	2.26e-05	3	96	2	15845899
Pubmed	Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1.	POLR2A CDC73	2.26e-05	3	96	2	30541148
Pubmed	Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase.	PTPRC LCK	2.26e-05	3	96	2	7507203
Pubmed	A genome-wide association study identifies a gene network of ADAMTS genes in the predisposition to pediatric stroke.	ADAMTS12 TRIM29	2.26e-05	3	96	2	22990015
Pubmed	CD45 protein-tyrosine phosphatase associates with the WW domain-containing protein, CD45AP, through the transmembrane region.	PTPRC LCK	2.26e-05	3	96	2	7499298
Pubmed	CD45 signals outside of lipid rafts to promote ERK activation, synaptic raft clustering, and IL-2 production.	PTPRC LCK	2.26e-05	3	96	2	15661907
Pubmed	Galectin-1, a natural ligand for the receptor-type protein tyrosine phosphatase CD45.	PTPRC LCK	2.26e-05	3	96	2	10369126
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MRPS31 ADAMTS12 RBM22 ARMC3 TIMM21 ZNF658 LMLN ZBTB21 MRPS9 DGKA DUOX2 MYOM2 EMC8 HNRNPAB	4.15e-05	1442	96	14	35575683
Pubmed	Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.	TTLL9 TTLL13 AGBL3	4.49e-05	25	96	3	29593216
Pubmed	CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycosphingolipid-rich plasma membrane domains of human peripheral blood lymphocytes.	PTPRC LCK	4.51e-05	4	96	2	9573028
Pubmed	Aurora A drives early signalling and vesicle dynamics during T-cell activation.	POLR2A LCK	4.51e-05	4	96	2	27091106
Pubmed	Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.	PCDH15 USH2A	4.51e-05	4	96	2	18463160
Pubmed	Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase-deficient mice.	PTPRC LCK	4.51e-05	4	96	2	7807014
Pubmed	Antiproliferative action of interferon-alpha requires components of T-cell-receptor signalling.	PTPRC LCK	4.51e-05	4	96	2	9403695
Pubmed	The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.	PTPRD PTPRF	4.51e-05	4	96	2	8524829
Pubmed	Integrin-mediated tyrosine phosphorylation of Shc in T cells is regulated by protein kinase C-dependent phosphorylations of Lck.	PTPRC LCK	4.51e-05	4	96	2	12589038
Pubmed	Substrate specificities and activities of AZAP family Arf GAPs in vivo.	ACAP2 ARAP1	4.51e-05	4	96	2	18003747
Pubmed	Anti-CD45 isoform antibodies enhance phagocytosis and gene expression of IL-8 and TNF-alpha in human neutrophils by differential suppression on protein tyrosine phosphorylation and p56lck tyrosine kinase.	PTPRC LCK	4.51e-05	4	96	2	12100025
Pubmed	Ezrin is a substrate for Lck in T cells.	PTPRC LCK	4.51e-05	4	96	2	12560083
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MRPS31 ATP6V1A VPS11 ABCB7 ATP2C1 HEATR6 MRPS9 OLA1 C1orf50 DIPK2A	4.56e-05	754	96	10	33060197
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	POLR2A ZBTB21 UPF3B CDC73 OLA1 HNRNPAB GADD45GIP1	6.97e-05	364	96	7	24778252
Pubmed	Staging and resetting T cell activation in SMACs.	PTPRC LCK	7.50e-05	5	96	2	12244310
Pubmed	Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.	PTPRD PTPRF	7.50e-05	5	96	2	10777529
Pubmed	Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis.	POLG GADD45GIP1	7.50e-05	5	96	2	27986797
Pubmed	Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.	PTPRD PTPRF	7.50e-05	5	96	2	22357843
Pubmed	Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.	PCDH15 USH2A	7.50e-05	5	96	2	16301216
Pubmed	Association of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell lines.	PTPRC LCK	7.50e-05	5	96	2	8570203
Pubmed	Selective regulation of Lyn tyrosine kinase by CD45 in immature B cells.	PTPRC LCK	7.50e-05	5	96	2	7499277
Pubmed	Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.	PTPRD PTPRF	1.12e-04	6	96	2	19273906
Pubmed	Characterization of Lnk. An adaptor protein expressed in lymphocytes.	LCK NOS1	1.12e-04	6	96	2	9169414
Pubmed	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.	MRPS31 DMGDH ATP6V1A ABCB7 POLG EMC8 NDUFA4 GOT2	1.32e-04	542	96	8	14651853
Pubmed	Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.	PTPRD PTPRF	1.57e-04	7	96	2	29073098
Pubmed	Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.	PTPRC PTPRF	1.57e-04	7	96	2	1454056
Pubmed	RNA polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA polymerase II.	POLR2A CDC73	1.57e-04	7	96	2	26659056
Pubmed	Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.	PCDH15 USH2A	1.57e-04	7	96	2	20058854
Pubmed	Subdomain X of the kinase domain of Lck binds CD45 and facilitates dephosphorylation.	PTPRC LCK	1.57e-04	7	96	2	14625311
Pubmed	The parafibromin tumor suppressor protein is part of a human Paf1 complex.	POLR2A CDC73	1.57e-04	7	96	2	15632063
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	RBM22 GALM POLR2A UPF3B DHX33 TRIM29 GADD45GIP1	1.66e-04	419	96	7	33001583
Pubmed	Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.	PCDH15 USH2A	2.09e-04	8	96	2	19683999
Pubmed	UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes.	PCDH15 USH2A	2.09e-04	8	96	2	18484607
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	PTPRD PTPRF	2.09e-04	8	96	2	37591863
Pubmed	Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.	PCDH15 USH2A	2.09e-04	8	96	2	16545802
Pubmed	Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.	PTPRD PTPRF	2.09e-04	8	96	2	28637841
Pubmed	ABCE1 is a highly conserved RNA silencing suppressor.	ATP6V1A PTPRF TIMM21 NDUFA4 GADD45GIP1	2.62e-04	204	96	5	25659154
Pubmed	The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.	POLR2A CDC73	2.68e-04	9	96	2	20178742
Pubmed	Elongation factor 1 alpha1 and genes associated with Usher syndromes are downstream targets of GBX2.	PCDH15 USH2A	2.68e-04	9	96	2	23144817
Pubmed	Genetic modifiers of muscular dystrophy: implications for therapy.	SGCG NOS1	2.68e-04	9	96	2	16916601
Pubmed	The human PAF complex coordinates transcription with events downstream of RNA synthesis.	POLR2A CDC73	2.68e-04	9	96	2	16024656
Pubmed	The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.	POLR2A CDC73	2.68e-04	9	96	2	15923622
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	JPH1 ATP6V1A ATP2C1 PTPRF TIMM21 CYP51A1 EMC8 MAPRE2 CEP97 DIPK2A	2.79e-04	942	96	10	31073040
Pubmed	Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.	PCDH15 USH2A	3.34e-04	10	96	2	24618850
Pubmed	Usher protein functions in hair cells and photoreceptors.	PCDH15 USH2A	3.34e-04	10	96	2	24239741
Pubmed	Real-time resolution of point mutations that cause phenovariance in mice.	PTPRC LCK	3.34e-04	10	96	2	25605905
Pubmed	A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.	ARMC3 DLL1	3.34e-04	10	96	2	23437001
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	RBM22 KIF23 DSC3 POLR2A MAPRE2 HNRNPAB CEP97	3.42e-04	472	96	7	38943005
Pubmed	Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development.	PTPRC LCK DLL1	3.86e-04	51	96	3	19164599
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	MRPS31 DHX16 RBM22 HEATR6 POLR2A MRPS9 UPF3B HNRNPAB GOT2	4.00e-04	807	96	9	22681889
GeneFamily	Tubulin tyrosine ligase family	TTLL9 TTL TTLL13	1.50e-05	14	64	3	779
GeneFamily	Fibronectin type III domain containing	SDK2 PTPRC PTPRD PTPRF MYOM2 USH2A	2.15e-05	160	64	6	555
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRC PTPRD PTPRF	5.38e-05	21	64	3	813
GeneFamily	DEAH-box helicases	DHX16 DHX33	1.43e-03	16	64	2	500
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SDK2 PTPRD PTPRF MYOM2	2.54e-03	161	64	4	593
GeneFamily	T cell receptor beta locus at 7q34	TRBV5-7 TRBV5-5 TRBV5-4	3.63e-03	87	64	3	372
ToppCell	COVID-19-T_cells-NK_cells\|COVID-19 / group, cell type (main and fine annotations)	C1orf21 PTPRC RASA2 PLCL2 MYOM2 LCK	3.44e-06	189	96	6	b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCell	droplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+Krt14+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 PTPRF KCNK1 TRIM29 DLL1 SDC1	3.99e-06	194	96	6	37803f4abf1aa1ad771c9cd293933003d7101e70
ToppCell	droplet-Tongue\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRF DSC3 OLA1 TRIM29 SDC1 GOT2	4.11e-06	195	96	6	e460b09ae354b579ce552acebdaa5877a6e62343
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ADAMTS12 C1orf21 PTPRD CILP ITGA10 TRIM29	4.24e-06	196	96	6	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	LRGUK AMPD3 KIF23 ARMC3 TTLL9 KCNK1	4.36e-06	197	96	6	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	Skin\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	PTPRF DSC3 EXPH5 DGKA TRIM29 SDC1	4.62e-06	199	96	6	6be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRF DSC3 UGT1A6 DGKA TRIM29 SDC1	4.62e-06	199	96	6	ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell	Biopsy_IPF-Epithelial-Basal\|Biopsy_IPF / Sample group, Lineage and Cell type	SDK2 DSC3 BEND5 UGT1A6 TRIM29 SDC1	4.76e-06	200	96	6	5cea84581201cee7ba8141b96e65864f4fd67113
ToppCell	facs-Aorta-Heart-3m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGD LRGUK PCDH15 MMP8 USH2A	1.28e-05	139	96	5	22a769d5195ed761ef333ef542746e1ba617a698
ToppCell	facs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HGD LRGUK PCDH15 MMP8 USH2A	1.28e-05	139	96	5	292533e04178dd36d57377562077f9deb2cb9746
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRGUK ARMC3 TTLL9 DUOX2 AK7	1.90e-05	151	96	5	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRGUK ARMC3 TTLL9 DUOX2 AK7	1.90e-05	151	96	5	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRGUK ARMC3 TTLL9 DUOX2 AK7	2.16e-05	155	96	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRGUK ARMC3 TTLL9 DUOX2 AK7	2.16e-05	155	96	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RBM22 PTPRF SGCG NRG3 TSPYL4	2.30e-05	157	96	5	f086753b51860e23f1275bd75e8802d2a7d7b70a
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	JPH1 TRBV5-7 TRBV5-5 DGKA LCK	2.67e-05	162	96	5	a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRPS31 KIF23 LMLN PCDH15 MOSMO	3.76e-05	174	96	5	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRF KCNK1 ARHGEF38 ARHGAP8 SDC1	4.30e-05	179	96	5	ca70a5518c5a5392e088c103e0cb44aa084f5332
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRF KCNK1 ARHGEF38 ARHGAP8 SDC1	4.30e-05	179	96	5	c451b074b04eb5d6c575c6abaedda579c6744bbf
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRF DSC3 DUOX2 TRIM29 SDC1	4.65e-05	182	96	5	678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRF DSC3 DUOX2 TRIM29 SDC1	4.65e-05	182	96	5	8d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRF DSC3 EXPH5 TRIM29 SDC1	4.90e-05	184	96	5	45ff845ceed5960a997545c1009012b65e377d50
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3\|TCGA-Lung / Sample_Type by Project: Shred V9	SDK2 DSC3 TRIM29 ACAP2 DIPK2A	4.90e-05	184	96	5	ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRF DSC3 EXPH5 TRIM29 SDC1	4.90e-05	184	96	5	2cc2646dee3c6001f7c10b7449c17d1935021958
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-mature_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	C1orf21 PTPRC MYOM2 LCK MAPRE2	5.16e-05	186	96	5	165d02be3b3eaeb8784a2b0b2020928b21a19bc7
ToppCell	facs-Lung-18m-Epithelial-alveolar_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRF KCNK1 ARHGEF38 ARHGAP8 SDC1	5.16e-05	186	96	5	c7214e762b3b48197fdd0b36a50a4de2550a888f
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PTPRC GALM UGT1A6 DGKA LCK	5.43e-05	188	96	5	e5c480b9a030536578f1cc91fb61738f752525b3
ToppCell	343B-Lymphocytic-ILC\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ATP2C1 TIMM21 ZBTB21 DIPK2A ARAP1	5.56e-05	189	96	5	c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCell	IPF-Lymphoid-NK\|IPF / Disease state, Lineage and Cell class	C1orf21 PTPRC MYOM2 LCK MAPRE2	5.56e-05	189	96	5	d92e880162450f8d01e4b8784eb625275cb8e03e
ToppCell	droplet-Lung-nan-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRF KCNK1 ARHGEF38 SDC1 AK7	5.70e-05	190	96	5	b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	PTPRC GALM UGT1A6 DGKA LCK	5.85e-05	191	96	5	c5e22df4a8741b8096cdd1618271fd48d6265846
ToppCell	facs-Skin\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRF DSC3 EXPH5 TRIM29 SDC1	5.85e-05	191	96	5	ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell	droplet-Lung-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PTPRF KCNK1 ARHGEF38 SDC1 AK7	5.85e-05	191	96	5	1b59f1cad6c1a6a5938afa9195164918e3ff4e86
ToppCell	nucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-NK\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PTPRC PLCL2 MYOM2 LCK MAPRE2	5.99e-05	192	96	5	a06d5d3c2537f8d2b1dc6b6f3e88a80b5c2a1850
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SGCG DUOX2 USH2A TAF1L AK7	6.14e-05	193	96	5	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	background-NK_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	PTPRC PTPRD RASA2 PLCL2 MYOM2	6.14e-05	193	96	5	f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PTPRF EXPH5 KCNK1 ARHGAP8 SDC1	6.14e-05	193	96	5	c1817ad675b9f9d2d3436c8b9646edf89f0d4c82
ToppCell	E16.5-samps-Epithelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	PTPRF EXPH5 KCNK1 ARHGAP8 SDC1	6.14e-05	193	96	5	1cb5a1cffa2b4a3bfecca16b791c1992edeb237d
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PTPRC RASA2 PLCL2 MYOM2 LCK	6.14e-05	193	96	5	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	10x5'-Lung-Lymphocytic_NK-NK_CD16\|Lung / Manually curated celltypes from each tissue	C1orf21 PTPRC MYOM2 LCK MAPRE2	6.45e-05	195	96	5	e91e7f89163c615b706f3297b641b1e4c966f5e6
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRPS31 ARMC3 TTLL9 DUOX2 AK7	6.45e-05	195	96	5	79dc031258579ea328181dda33710dd897f1064a
ToppCell	10x5'-Lung-Lymphocytic_NK\|Lung / Manually curated celltypes from each tissue	C1orf21 PTPRC MYOM2 LCK MAPRE2	6.45e-05	195	96	5	a5a10ef9254c266316e5591bec19e159cc3caead
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DSC3 UGT1A6 TRIM29 DLL1 SDC1	6.61e-05	196	96	5	c5adab88140a465698abcbedc6505a43cae7bfd1
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SDK2 UGT1A6 TRIM29 DLL1 SDC1	6.61e-05	196	96	5	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PTPRF DSC3 NDUFA4 TRIM29 SDC1	6.77e-05	197	96	5	8623972c7a70b3565b7a3a4afe93f1e012008201
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	SDK2 UGT1A6 TRIM29 DLL1 SDC1	6.77e-05	197	96	5	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DSC3 UGT1A6 TRIM29 DLL1 SDC1	6.77e-05	197	96	5	de772bd2b4cda843777ac879b1087e6444199dfb
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSC3 TRIM29 HNRNPAB SDC1 GOT2	6.77e-05	197	96	5	2430f31d9312338e0ca23bfc6bdb0365340860fd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSC3 DUOX2 LCK TRIM29 SDC1	6.77e-05	197	96	5	9ee927d005eb17843e2516c8006eb192c6ad2af8
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DSC3 BEND5 UGT1A6 TRIM29 SDC1	6.93e-05	198	96	5	de5987588b9fa9ee8c595ba06d7d844ead0e3c74
ToppCell	Epithelial_cells-Basal_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	SDK2 UGT1A6 DGKA TRIM29 DLL1	6.93e-05	198	96	5	4235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DSC3 DUOX2 LCK TRIM29 SDC1	6.93e-05	198	96	5	3371276410dba693c238b383d990b89371b14d8d
ToppCell	distal-Hematologic-CD4+_Memory/Effector_T-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PTPRC GALM RASA2 DGKA LCK	6.93e-05	198	96	5	7a89635f3567b4d2e6cd684c47be2e015d72a357
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPRF EXPH5 KCNK1 DUOX2 TRIM29	6.93e-05	198	96	5	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	droplet-Skin-nan-21m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1orf21 PTPRF DSC3 TRIM29 SDC1	6.93e-05	198	96	5	e2d1ef4a4c89ce53b47d7d5b8a45e71d3117e1b1
ToppCell	droplet-Skin-nan-21m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1orf21 PTPRF DSC3 TRIM29 SDC1	6.93e-05	198	96	5	38a58e6eaae89ce1cadf2e04169c974e13587e50
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_basal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DSC3 UGT1A6 TRIM29 DLL1 SDC1	7.10e-05	199	96	5	995d710d7302272e7951a5a5d766d1039089ee2b
ToppCell	PSB-critical-LOC-Epithelial-Basal\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DSC3 BEND5 UGT1A6 DGKA SDC1	7.10e-05	199	96	5	2add64c3e4cb6384ec381f34c3f1f77e13e3f27c
ToppCell	NS-critical-d_07-13-Epithelial\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PTPRF EXPH5 KCNK1 DUOX2 TRIM29	7.10e-05	199	96	5	b88a81cd2a89f4d27100c96ae4324dcee68daf83
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARMC3 KCNK1 ARHGEF38 TRIM29 AK7	7.10e-05	199	96	5	8649c2380285a668782d75eb076ce548eed0911d
ToppCell	Bronchial-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PTPRF EXPH5 ARHGEF38 TRIM29 SDC1	7.27e-05	200	96	5	d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PTPRF DSC3 EXPH5 TRIM29 SDC1	7.27e-05	200	96	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARMC3 KCNK1 ARHGEF38 DUOX2 AK7	7.27e-05	200	96	5	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	Tracheal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PTPRF DSC3 UGT1A6 TRIM29 SDC1	7.27e-05	200	96	5	efd461c687155c84ef590352207e6fe4ba392a90
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	DSC3 UGT1A6 TRIM29 DLL1 SDC1	7.27e-05	200	96	5	592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCell	Biopsy_Other_PF-Epithelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	PTPRF EXPH5 KCNK1 ARHGEF38 SDC1	7.27e-05	200	96	5	1ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCell	Skin-Keratinocytes\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	PTPRF DSC3 EXPH5 TRIM29 SDC1	7.27e-05	200	96	5	59d72395199bc30df0e811fbc99149694e208860
ToppCell	Biopsy_Other_PF-Immune-NK_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	C1orf21 PTPRC MYOM2 LCK MAPRE2	7.27e-05	200	96	5	418d665b8431697fc9e516258c9fe374257750d9
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PTPRC RASA2 MYOM2 LCK MAPRE2	7.27e-05	200	96	5	d1cfc4ef6ae75c486427e393d98b84a2a7ec67fe
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-NK\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	C1orf21 PTPRC MYOM2 LCK MAPRE2	7.27e-05	200	96	5	0a6fc7eff94e2f71af9f31a01779aafd2f4a6699
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DSC3 UGT1A6 TRIM29 DLL1 SDC1	7.27e-05	200	96	5	8cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	PTPRC ARMC3 TTLL9 KCNK1 AK7	7.27e-05	200	96	5	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	DSC3 UGT1A6 TRIM29 DLL1 SDC1	7.27e-05	200	96	5	61811380d9252f12f27b7ad4752380b52692677f
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ARMC3 KCNK1 ARHGEF38 DUOX2 AK7	7.27e-05	200	96	5	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	367C-Lymphocytic-ILC-ILC-1\|ILC / Donor, Lineage, Cell class and subclass (all cells)	NBEAL1 GADD45GIP1	1.25e-04	8	96	2	7e2e4c7bacc88c7bee10751805cb4caaf9da6aee
ToppCell	Lymphoid-T_cells_(Cd4+_Tnaive-Tcm)\|World / shred on cell class and cell subclass (v4)	PTPRC DGKA LCK CEP97	1.91e-04	132	96	4	14a371fc7e47a45b84f10a939163d030ad967de5
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ADAMTS12 GALM TTLL9 ITGA10	2.02e-04	134	96	4	a3547a68012d879d4dfe80394eace70808722e43
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)\|Striatum / BrainAtlas - Mouse McCarroll V32	ADAMTS12 GALM TTLL9 ITGA10	2.02e-04	134	96	4	9458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGA10 TSPYL4 CEP97 AGBL3	2.59e-04	143	96	4	b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPD3 PTPRC CILP MMP8	2.73e-04	145	96	4	88e463d5396a8fea2b7b1ecf3c9b144e16b35234
ToppCell	E18.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPD3 PTPRC CILP MMP8	2.73e-04	145	96	4	911fee7f27694393e348d94470a1a4e890038902
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTPRF KCNK1 ARHGEF38 SDC1	2.88e-04	147	96	4	aba44c7057096483c4293a7ebcf8ccc8baed0231
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_and_Lobular_Carcinoma-6\|TCGA-Breast / Sample_Type by Project: Shred V9	ADAMTS12 PTPRD CILP ARHGEF38	3.03e-04	149	96	4	3904f8ce9078de238600ceceee0116af52256a1c
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPRC PLCL2 MYOM2 ARAP1	3.19e-04	151	96	4	b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	PTPRC TRBV5-4 MYOM2 LCK	3.19e-04	151	96	4	512f7f37ddc8dfa1906f7fff92b571929236c9ea
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRC DGKA LCK GADD45GIP1	3.19e-04	151	96	4	75c068b3e3aae5f9ba64d5fa5d1e2105a60e4293
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARMC3 ARHGEF38 LCK NRG3	3.19e-04	151	96	4	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	P15-Epithelial-epithelial_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTPRF KCNK1 ARHGEF38 SDC1	3.27e-04	152	96	4	00d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCell	COVID-19_Severe-CD8+_T_naive\|World / disease group, cell group and cell class	EXPH5 DGKA LCK ARHGAP8	3.43e-04	154	96	4	b568417d88a78d8c46688847f0f5f4989bd36387
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRGUK ARMC3 TTLL9 AK7	3.43e-04	154	96	4	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRGUK ARMC3 TTLL9 AK7	3.43e-04	154	96	4	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	facs-BAT-Fat-24m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C1orf21 HYAL3 LCK NRG3	3.52e-04	155	96	4	550e7e7e52829244ead829e5be010bfdc71e2ba5
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DMGDH PTPRD PTPRF SDC1	3.61e-04	156	96	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DHX16 DMGDH SGCG DLL1	3.61e-04	156	96	4	d411116d54add2d4fe649a97ac54cb94c085312f
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_A\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	C1orf21 C16orf86 KCNK1 MYOM2	3.69e-04	157	96	4	542944030cd9b3f3559e64f9f6598694d74003c0
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF23 PTPRC DGKA LCK	3.87e-04	159	96	4	e9c51e611ebd427bbe51e3e036c14122c36ea372
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ABCB7 PTPRC DGKA LCK	3.87e-04	159	96	4	8d958d79f5eb3ab683d1245ae7f4f22a2cefbc55
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DUOX2 NRG3 TSPYL4 DIPK2A	3.87e-04	159	96	4	9f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DUOX2 NRG3 TSPYL4 DIPK2A	3.87e-04	159	96	4	c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPD3 VPS13D PTPRC LCK	3.97e-04	160	96	4	b2d8940ea8c068273b7da1589d3d6ae5110d8209
Disease	non-alcoholic fatty liver disease severity measurement	PTPRD NRG3 ARHGAP8	8.51e-05	28	90	3	EFO_0008421
Disease	Usher Syndrome, Type II	PCDH15 USH2A	9.15e-05	5	90	2	C1568249
Disease	thrombin-antithrombin complex measurement	PTPRC KCNK1	5.95e-04	12	90	2	EFO_0007775
Disease	Opioid use measurement	PTPRD MYOM2	9.41e-04	15	90	2	EFO_0009937
Disease	stroke	ADAMTS12 PTPRF NBEAL1 TRIM29	1.00e-03	144	90	4	EFO_0000712
Disease	decreased susceptibility to hepatitis C infection	PTPRD OFCC1	1.07e-03	16	90	2	EFO_0010101
Disease	obesity (biomarker_via_orthology)	PTPRF NOS1 SDC1 GOT2	1.08e-03	147	90	4	DOID:9970 (biomarker_via_orthology)
Disease	androstenedione measurement, estrone measurement	PTPRD ARMC3	1.36e-03	18	90	2	EFO_0007970, EFO_0007972
Disease	Feeding difficulties	POLR2A GOT2	1.36e-03	18	90	2	C0232466

Protein segments in the cluster

Peptide	Gene	Start	Entry
DFDNQKVYAVYRGPE	BEND5	31	Q7L4P6
DQIKYYRNNPGQDGR	AGBL3	261	Q8NEM8
YVNYCNPELNQAGKG	C16orf86	196	Q6ZW13
IPAAYNRYDQERFKG	CDC73	286	Q6P1J9
LAEAQGQKGYVPANY	ARHGEF38	756	Q9NXL2
NIINDGFYDYGRINP	ARMC3	566	Q5W041
LYGQPGDETYQDIFR	ACAP2	741	Q15057
QIPQYLFEEGYTNKG	DHX16	431	O60231
GLQQDYIRKAEYPFS	ATP2C1	441	P98194
EDPEKYYLNGGFIIQ	ADAMTS12	746	P58397
GQNYYKEGPEGNDIR	AMPD3	716	Q01432
DILQGYPKDISNYGF	MMP8	356	P22894
KRPFGQSFVYIYDNG	NBEAL1	676	Q6ZS30
QNIKDRYYGINDPVA	RBM22	196	Q9NW64
YQGPQKEPDDYSNFV	RASA2	786	Q15283
GKYRQQGRNYIVEDG	OLA1	366	Q9NTK5
LQGGARVIFDDYKPY	PCDHB18P	6	Q96TA0
NPYFNSLEQKDLVGY	NRG3	576	P56975
GEPAKFYGYDNLQRQ	HOXD8	131	P13378
QKNPDSYNGAVRENY	NUDCD3	176	Q8IVD9
ETEAPGGYKFYLQNR	GLOD4	131	Q9HC38
YVPGEGYNQKFRELY	KCNK1	231	O00180
NQPEIFKNYGAEKYG	LMLN	506	Q96KR4
FYQPGPDYVKQRFQE	JPH1	416	Q9HDC5
YLQFQRPQGFEYKSG	DUOX2	1286	Q9NRD8
KYVQGDAIGYEGFQQ	DGKA	41	P23743
AKIFNYGRIYGAGQP	POLG	946	P54098
VPGKREQYGSVDQYA	HEATR6	1026	Q6AI08
YRPIDYGIFGKEQQL	EXPH5	1881	Q8NEV8
YKIRNLDNGGFYISP	LCK	181	P06239
RVDLYIKINQNFPGY	LRGUK	561	Q96M69
NSQLIRYAGYKQPDG	NOS1	481	P29475
SAEPKGNEYGRNYFD	OFCC1	81	Q8IZS5
DINKDFQPYYGEGGR	PCDH15	1336	Q96QU1
GYVFLDNKGQEYPAI	UPF3B	116	Q9BZI7
YGGQDVFLNNKYDRA	BECN2	336	A8MW95
ELEGYLQKQPYFGAV	GALM	61	Q96C23
NENGDAPGRYDIFQY	GRM6	461	O15303
NGYKAYDPENRNGNG	DSC3	491	Q14574
QDGKPYYAQIRGFIQ	GATAD1	161	Q8WUU5
GYIKNPYNIFDGVIV	CACNA1G	801	O43497
GFKARYPAVDYNLVQ	DLL1	631	O00548
GFYARNYNPQAKDVR	CEP97	571	Q8IW35
GKEYVLNRNRYGVEP	C19orf71	146	A6NCJ1
LNVKNVYFAQYGEPR	DIPK2A	86	Q8NDZ4
RYLQDNPASGEKFAY	CYP51A1	431	Q16850
DPQEQLYKAYTGFEQ	HYAL3	161	O43820
GKNYQNGDVFGDEYR	C1orf21	21	Q9H246
QYFNGAPVLYLEGRQ	DHX33	241	Q9H6R0
GFQGQQYILERGEYP	CRYBA4	61	P53673
RESYGFNNIVGYPKE	DMGDH	446	Q9UI17
FNNIVGYPKEERFAG	DMGDH	451	Q9UI17
NYDGKEYDPVEARQG	MAPRE2	161	Q15555
FLGPQNKETGRVYVY	ITGA10	511	O75578
QLGPRYAAKQFARYG	GADD45GIP1	51	Q8TAE8
GYYQANERVKDASPN	EMC8	91	O43402
PDAGRYYVQAVNDKN	SDK2	176	Q58EX2
PGNIYYLYKRESGQQ	C1orf50	116	Q9BV19
DGYRQQKAYIATQGP	PTPRF	1701	P10586
DGYRQQKAYIATQGP	PTPRD	1706	P23468
DRQVPGGYTVINKYQ	HGD	236	Q93099
TPEGYRLNRNGDYKE	KIF23	56	Q02241
IQFDEGYDNYPGQEK	MRPS31	226	Q92665
YNDKPFRQGDQVYAF	USH2A	556	O75445
YRPFYVNKGNGIGSN	TRIM29	571	Q14134
PKEVYQQQQYGSGGR	HNRNPAB	231	Q99729
LSNDEYYFPKQQGLR	TAF1L	586	Q8IZX4
YANENPGDFVNYNKR	PLCL2	656	Q9UPR0
LGPNDQYKFYSVNVD	NDUFA4	56	O00483
VVRDVFYDGNPKYEQ	SELENOO	226	Q9BVL4
YSLEEPKQANGGAYQ	SDC1	286	P18827
ERPENQYVYKIGIYG	SGCG	16	Q13326
FYEPQKGSIYLAGQN	ABCB7	521	O75027
NLGVGAYRDDNGKPY	GOT2	61	P00505
EGKYRRYHPLFGNQE	ARAP1	646	Q96P48
RSFYRQNGEPYIGKV	CILP	606	O75339
GPQFIFQYYEKEERG	TRBV5-5	61	A0A597
FQYYEKEERGRGNFP	TRBV5-5	66	A0A597
NKGNGQGEDRNLLYY	ZBTB21	296	Q9ULJ3
QDGVLYLYEQGKLFQ	VPS11	676	Q9H270
GRIKVNGIDYQLYFP	MRPS9	291	P82933
SQYPGAKYIIRDNGD	POLR2A	411	P24928
QGNPYFRNEGLVKEY	TSPYL4	301	Q9UJ04
KDDFLQQNGYTPYDR	ATP6V1A	516	P38606
GPQFIFQYYEKEERG	TRBV5-7	61	A0A0A0MS05
FQYYEKEERGRGNFP	TRBV5-7	66	A0A0A0MS05
GPQFIFQYYREEENG	TRBV5-4	61	A0A0C4DH59
FQYYREEENGRGNFP	TRBV5-4	66	A0A0C4DH59
RLYNQGKPVNFDDYG	ARHGAP8	276	P85298
LQAKGRVFRNPYNYG	ZDHHC16	311	Q969W1
QVKENPGSGEYDFRY	TIMM21	211	Q9BVV7
DEFLNQRYPGYFKVD	ZNF658	71	Q5TYW1
QRYIENPYLIGGRKF	TTLL9	211	Q3SXZ7
PYDQEELKNRYQSFG	UGT1A6	81	P19224
NYINASYIDGFKEPR	PTPRC	706	P08575
PGLVQLVNYYRGADK	TTL	56	Q8NG68
PADYGDFQSYGRQRK	TTLL13	181	A6NNM8
QGGTPIRYYFENLKI	VPS13D	3976	Q5THJ4
FYINEVGGQPYKLPN	MOSMO	121	Q8NHV5
QGYILDGFPKTYDQA	AK7	476	Q96M32
QAAEPGKYRIESNYG	MYOM2	196	P54296