Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 KIF13B ABCC1 MYO5B HSPA4L SAE1 RNF213 NLRP10 ACIN1 CHD6 ABCG2 ATP6V0D2 ATP2B1 PIF1	4.56e-06	614	106	14	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal protein binding	KIF13B ANK3 CLASP1 IQGAP2 MYO5B CLASP2 JAKMIP3 IQGAP1 FMNL3 LMOD3 ABLIM1 SYNE3 MICAL2 TTLL11 ABCG2 TRAK2 CORO7	6.49e-05	1099	106	17	GO:0008092
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF13B ABCC1 MYO5B RNF213 NLRP10 ACIN1 CHD6 ABCG2 ATP2B1 PIF1	1.20e-04	441	106	10	GO:0016887
GeneOntologyMolecularFunction	actin filament binding	IQGAP2 MYO5B CLASP2 IQGAP1 FMNL3 ABLIM1 SYNE3	2.10e-04	227	106	7	GO:0051015
GeneOntologyMolecularFunction	actin binding	IQGAP2 MYO5B CLASP2 IQGAP1 FMNL3 LMOD3 ABLIM1 SYNE3 MICAL2 CORO7	2.34e-04	479	106	10	GO:0003779
GeneOntologyMolecularFunction	intracellularly cGMP-activated cation channel activity	CNGA1 CNGA4	5.76e-04	7	106	2	GO:0005223
GeneOntologyMolecularFunction	intracellularly ligand-gated monoatomic ion channel activity	ITPR1 CNGA1 CNGA4	7.07e-04	33	106	3	GO:0005217
GeneOntologyBiologicalProcess	positive regulation of serine-type peptidase activity	SEMG1 SEMG2	7.53e-05	3	104	2	GO:1902573
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly	IQGAP2 IQGAP1	7.53e-05	3	104	2	GO:1903475
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP1	7.53e-05	3	104	2	GO:1903479
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in mitotic cytokinesis	IQGAP2 IQGAP1	7.53e-05	3	104	2	GO:1902407
GeneOntologyBiologicalProcess	positive regulation of serine-type endopeptidase activity	SEMG1 SEMG2	7.53e-05	3	104	2	GO:1900005
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP1	1.50e-04	4	104	2	GO:2000689
GeneOntologyBiologicalProcess	negative regulation of cilium-dependent cell motility	SEMG1 SEMG2	1.50e-04	4	104	2	GO:1902020
GeneOntologyBiologicalProcess	negative regulation of cilium movement	SEMG1 SEMG2	1.50e-04	4	104	2	GO:0003354
GeneOntologyBiologicalProcess	negative regulation of flagellated sperm motility	SEMG1 SEMG2	1.50e-04	4	104	2	GO:1901318
GeneOntologyBiologicalProcess	mating plug formation	SEMG1 SEMG2	1.50e-04	4	104	2	GO:0042628
GeneOntologyBiologicalProcess	intracellular transport	KIF13B RGPD2 RANBP2 CDC42BPA ANK3 MYO5B VTA1 VPS54 TFG PIK3R4 EVI5 TOMM70 JUP SYNE3 ITSN2 ATP6V0D2 TRAK2 HERC2 CORO7	1.58e-04	1496	104	19	GO:0046907
GeneOntologyBiologicalProcess	positive regulation of protein localization	ANK3 MYO5B SAE1 CLASP2 PTBP1 IQGAP1 ITPR1 BLK TOMM70 JUP TRIM8	1.95e-04	591	104	11	GO:1903829
GeneOntologyBiologicalProcess	actomyosin structure organization	CDC42BPA CLASP1 IQGAP2 ARHGEF18 CLASP2 IQGAP1 LMOD3	2.10e-04	239	104	7	GO:0031032
GeneOntologyBiologicalProcess	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	CLASP1 CLASP2	2.49e-04	5	104	2	GO:1904261
GeneOntologyBiologicalProcess	regulation of basement membrane assembly involved in embryonic body morphogenesis	CLASP1 CLASP2	2.49e-04	5	104	2	GO:1904259
GeneOntologyBiologicalProcess	negative regulation of wound healing, spreading of epidermal cells	CLASP1 CLASP2	2.49e-04	5	104	2	GO:1903690
GeneOntologyBiologicalProcess	basement membrane assembly involved in embryonic body morphogenesis	CLASP1 CLASP2	2.49e-04	5	104	2	GO:2001197
GeneOntologyBiologicalProcess	response to magnesium ion	ANK3 SLC34A1 D2HGDH	2.64e-04	25	104	3	GO:0032026
GeneOntologyBiologicalProcess	xenobiotic transport across blood-brain barrier	ABCC1 ABCG2	3.73e-04	6	104	2	GO:1990962
GeneOntologyBiologicalProcess	embryonic retina morphogenesis in camera-type eye	HIPK1 HIPK2	3.73e-04	6	104	2	GO:0060059
GeneOntologyBiologicalProcess	fertilization	SEMG1 SEMG2 NOX5 TEX15 ITPR1 NELL2 EHMT2	3.75e-04	263	104	7	GO:0009566
GeneOntologyBiologicalProcess	spermatid differentiation	SEMG1 DNHD1 SEMG2 NUP210L VPS54 CEP128 EHMT2	4.59e-04	272	104	7	GO:0048515
GeneOntologyCellularComponent	cortical microtubule cytoskeleton	CLASP1 CLASP2	2.43e-04	5	104	2	GO:0030981
GeneOntologyCellularComponent	basal cortex	CLASP1 CLASP2	5.07e-04	7	104	2	GO:0045180
GeneOntologyCellularComponent	intracellular cyclic nucleotide activated cation channel complex	CNGA1 CNGA4	5.07e-04	7	104	2	GO:0017071
GeneOntologyCellularComponent	actin cytoskeleton	CDC42BPA ACACA IQGAP2 MYO5B IQGAP1 LMOD3 ABLIM1 JUP SH3PXD2A MICAL2	5.98e-04	576	104	10	GO:0015629
GeneOntologyCellularComponent	basal part of cell	ABCC1 ANK3 CLASP1 CLASP2 ITGB4 IQGAP1 SLC34A1 ATP2B1	6.04e-04	378	104	8	GO:0045178
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RGPD2 RANBP2	6.73e-04	8	104	2	GO:1990723
GeneOntologyCellularComponent	cell leading edge	CDC42BPA IQGAP2 CLASP2 ITGB4 IQGAP1 ABLIM1 PLA2G4F ATP2B1 INPP5J	8.78e-04	500	104	9	GO:0031252
GeneOntologyCellularComponent	lateral plasma membrane	ABCC1 ANK3 IQGAP1 JUP	1.06e-03	90	104	4	GO:0016328
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RGPD2 RANBP2	1.07e-03	10	104	2	GO:0044614
GeneOntologyCellularComponent	hemidesmosome	ITGB4 JUP	1.31e-03	11	104	2	GO:0030056
GeneOntologyCellularComponent	cell projection membrane	CLASP2 SLC34A1 ABCG2 PLA2G4F ATP2B1 CNGA1 CNGA4 INPP5J	1.41e-03	431	104	8	GO:0031253
GeneOntologyCellularComponent	cell cortex region	CLASP1 MYO5B CLASP2	1.46e-03	45	104	3	GO:0099738
Domain	HEAT	CLASP1 CLASP2 HEATR1 PIK3R4 JUP NIPBL	9.76e-07	58	107	6	IPR000357
Domain	HEAT	CLASP1 CLASP2 HEATR1 PIK3R4 JUP	7.91e-06	48	107	5	PF02985
Domain	TPR	RGPD2 RANBP2 PRPF6 IFIT3 TOMM70 TRANK1 TMTC3	9.36e-06	129	107	7	SM00028
Domain	TPR_repeat	RGPD2 RANBP2 PRPF6 IFIT3 TOMM70 TRANK1 TMTC3	1.14e-05	133	107	7	IPR019734
Domain	TPR-contain_dom	RGPD2 RANBP2 PRPF6 IFIT3 TOMM70 TRANK1 TMTC3	2.50e-05	150	107	7	IPR013026
Domain	Semenogelin	SEMG1 SEMG2	3.25e-05	2	107	2	PF05474
Domain	Semenogelin	SEMG1 SEMG2	3.25e-05	2	107	2	IPR008836
Domain	HEAT_REPEAT	CLASP1 CLASP2 HEATR1 PIK3R4 NIPBL	5.06e-05	70	107	5	PS50077
Domain	RasGAP_C	IQGAP2 IQGAP1	9.72e-05	3	107	2	IPR000593
Domain	RasGAP_C	IQGAP2 IQGAP1	9.72e-05	3	107	2	PF03836
Domain	ARM-type_fold	CLASP1 CLASP2 HEATR1 ITPR1 PIK3R4 FMNL3 JUP NIPBL GPRASP2	1.45e-04	339	107	9	IPR016024
Domain	TPR_1	RANBP2 PRPF6 IFIT3 TOMM70 TMTC3	1.68e-04	90	107	5	IPR001440
Domain	TPR_1	RANBP2 PRPF6 IFIT3 TOMM70 TMTC3	1.68e-04	90	107	5	PF00515
Domain	-	RGPD2 RANBP2 PRPF6 IFIT3 TOMM70 TRANK1 TMTC3	1.90e-04	207	107	7	1.25.40.10
Domain	CLZ	CNGA1 CNGA4	1.94e-04	4	107	2	PF16526
Domain	CLASP_N	CLASP1 CLASP2	1.94e-04	4	107	2	PF12348
Domain	CLASP_N_dom	CLASP1 CLASP2	1.94e-04	4	107	2	IPR024395
Domain	CLZ_dom	CNGA1 CNGA4	1.94e-04	4	107	2	IPR032406
Domain	Taxilin	TXLNGY TXLNB	1.94e-04	4	107	2	PF09728
Domain	TPR_8	PRPF6 IFIT3 TOMM70 TMTC3	2.40e-04	53	107	4	PF13181
Domain	HnRNP-L/PTB	PTBP2 PTBP1	3.22e-04	5	107	2	IPR006536
Domain	TPR_REGION	RGPD2 RANBP2 IFIT3 TOMM70 TRANK1 TMTC3	3.76e-04	165	107	6	PS50293
Domain	TPR	RGPD2 RANBP2 IFIT3 TOMM70 TRANK1 TMTC3	3.76e-04	165	107	6	PS50005
Domain	TPR-like_helical_dom	RGPD2 RANBP2 PRPF6 IFIT3 TOMM70 TRANK1 TMTC3	3.89e-04	233	107	7	IPR011990
Domain	ARM-like	CLASP1 CLASP2 HEATR1 PIK3R4 JUP NIPBL GPRASP2	9.31e-04	270	107	7	IPR011989
Domain	-	CLASP1 CLASP2 HEATR1 PIK3R4 JUP NIPBL	1.76e-03	222	107	6	1.25.10.10
Domain	Ran_BP1	RGPD2 RANBP2	2.07e-03	12	107	2	PF00638
Domain	RANBD1	RGPD2 RANBP2	2.07e-03	12	107	2	PS50196
Domain	RanBD	RGPD2 RANBP2	2.43e-03	13	107	2	SM00160
Domain	Ran_bind_dom	RGPD2 RANBP2	2.43e-03	13	107	2	IPR000156
Domain	RasGAP	IQGAP2 IQGAP1	2.83e-03	14	107	2	SM00323
Domain	RasGAP_CS	IQGAP2 IQGAP1	2.83e-03	14	107	2	IPR023152
Domain	RasGAP	IQGAP2 IQGAP1	3.25e-03	15	107	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	IQGAP2 IQGAP1	3.25e-03	15	107	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	IQGAP2 IQGAP1	3.25e-03	15	107	2	PS50018
Domain	P-loop_NTPase	DNHD1 KIF13B ABCC1 TPST1 MYO5B RNF213 IQGAP1 NLRP10 TRANK1 CHD6 ABCG2 PIF1	3.36e-03	848	107	12	IPR027417
Domain	cNMP-bd_CS	CNGA1 CNGA4	3.70e-03	16	107	2	IPR018488
Domain	-	IQGAP2 IQGAP1	3.70e-03	16	107	2	1.10.506.10
Domain	HEAT_type_2	CLASP1 PIK3R4	4.18e-03	17	107	2	IPR021133
Domain	RasGAP_dom	IQGAP2 IQGAP1	4.69e-03	18	107	2	IPR001936
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KIF13B RGPD2 RANBP2 IQGAP2 MYO5B HSPA4L PTBP2 PRPF6 HEATR1 PTBP1 CEP128 ERLIN1 IQGAP1 LMOD3 SH3PXD2A ITSN2 ACIN1 UGGT2 CHD6 ATP2B1 NIPBL	2.65e-09	1442	107	21	35575683
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TET2 ANK3 HIPK1 VPS54 JAKMIP3 REV3L IQGAP1 RUFY2 PIK3R4 ABLIM1 NELL2 FBN1 EHMT2 MICAL2 TRIM8 CHD6 HERC2 NIPBL GPRASP2	1.32e-08	1285	107	19	35914814
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ABCC1 MYO5B SAE1 HEATR1 TFG CEP128 TOMM70 ABLIM1 FBN1 XPNPEP3 UGGT2 HERC2 ATP2B1 GPRASP2	8.52e-08	754	107	14	33060197
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RANBP2 CDC42BPA ACACA MYO5B HSPA4L SAE1 CLASP2 PRPF6 PTBP1 ERLIN1 IQGAP1 ABLIM1 JUP MICAL2 WDR87 TTLL11 ACIN1	2.66e-07	1247	107	17	27684187
Pubmed	A human MAP kinase interactome.	RANBP2 CDC42BPA ANK3 HIPK1 HIPK2 ITGB4 ABLIM1 JUP ITSN2 CHD6 HERC2	3.29e-07	486	107	11	20936779
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DNHD1 RANBP2 TRAF1 ACACA HSPA4L CLASP2 PRPF6 HEATR1 PTBP1 TFG TSFM IQGAP1 PIK3R4 TOMM70 JUP ACIN1 ATP2B1 NIPBL	3.47e-07	1425	107	18	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ANK3 CLASP1 IQGAP2 MYO5B NAT9 HSPA4L CLASP2 PTBP1 IQGAP1 PIK3R4 TOMM70 ABLIM1 JUP MICAL2 ITSN2 CORO7 ATP2B1 CACNA2D3	3.69e-07	1431	107	18	37142655
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RANBP2 MYO5B PRPF6 HEATR1 PTBP1 TFG ERLIN1 IQGAP1 ABLIM1 JUP XPNPEP3 ACIN1 HERC2 ATP2B1 NIPBL	5.91e-07	1024	107	15	24711643
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RANBP2 ACACA SAE1 VTA1 PRPF6 HEATR1 PTBP1 ERLIN1 IQGAP1 PIK3R4 JUP MICAL2 ACIN1 HERC2 CORO7 ATP2B1 NIPBL	8.22e-07	1353	107	17	29467282
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ABCC1 TPST1 HSPA4L PBK RNF213 GCNT1 ITGB4 ERLIN1 ITPR1 JUP NELL2 FBN1 TMTC3 MICAL2 UGGT2 ATP2B1	8.39e-07	1201	107	16	35696571
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	KIF13B ANK3 IQGAP2 PTBP2 HIPK2 ARHGEF18 CLASP2 HEATR1 ITGB4 ERLIN1 ITPR1 JUP ACIN1 ATP2B1 D2HGDH	1.20e-06	1084	107	15	11544199
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KIF13B RGPD2 RANBP2 ANK3 CLASP1 IQGAP2 ARHGEF18 CLASP2 JAKMIP3 IQGAP1 ABLIM1 EHMT2 HERC2 NIPBL	1.58e-06	963	107	14	28671696
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	TET2 RANBP2 MYO5B PRPF6 PTBP1 IQGAP1 JUP NIPBL	2.11e-06	272	107	8	31010829
Pubmed	Defining the membrane proteome of NK cells.	ABCC1 RANBP2 CLASP1 RNF213 CLASP2 PRPF6 HEATR1 PTBP1 ITPR1 PIK3R4 TOMM70 SYNE3 HERC2 CORO7 ATP2B1	2.99e-06	1168	107	15	19946888
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CDC42BPA ACACA ANK3 PTBP2 HIPK2 ARHGEF18 RNF213 CLASP2 VPS54 ABLIM1 SH3PXD2A MICAL2 TTLL11 XPNPEP3 CHD6 FBXO21 ATP2B1	3.00e-06	1489	107	17	28611215
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	CDC42BPA ACACA PTBP1 ITGB4 IQGAP1 TMTC3 HERC2	3.21e-06	202	107	7	33005030
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	RANBP2 CDC42BPA HEATR1 PTBP1 IQGAP1 ACIN1 ATP2B1	3.21e-06	202	107	7	24639526
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RGPD2 RANBP2 ANK3	7.92e-06	13	107	3	31427429
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ABCC1 RANBP2 IQGAP2 HSPA4L RNF213 PRPF6 HEATR1 PTBP1 IFIT3 ERLIN1 IQGAP1 ITPR1 EVI5 TOMM70 ABLIM1 ATP2B1	8.52e-06	1440	107	16	30833792
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	RANBP2 SAE1 RNF213 PRPF6 PTBP1 IQGAP1 ACIN1 NIPBL	9.10e-06	332	107	8	32786267
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	RANBP2 ACACA CLASP1 IQGAP2 HSPA4L SAE1 CLASP2 PRPF6 HEATR1 IQGAP1 PIK3R4 JUP ACIN1 HERC2 D2HGDH	9.31e-06	1284	107	15	17353931
Pubmed	Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function.	CLASP1 CLASP2	9.38e-06	2	107	2	16914514
Pubmed	Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.	IQGAP2 IQGAP1	9.38e-06	2	107	2	24998570
Pubmed	Alternative splicing of brain-specific PTB defines a tissue-specific isoform pattern that predicts distinct functional roles.	PTBP2 PTBP1	9.38e-06	2	107	2	12213192
Pubmed	Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics.	CLASP1 CLASP2	9.38e-06	2	107	2	12837247
Pubmed	IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.	IQGAP2 IQGAP1	9.38e-06	2	107	2	20977743
Pubmed	[Isolation and structure determination of two peptides occurring in human seminal plasma].	SEMG1 SEMG2	9.38e-06	2	107	2	2757795
Pubmed	PTBP1 and PTBP2 Repress Nonconserved Cryptic Exons.	PTBP2 PTBP1	9.38e-06	2	107	2	27681424
Pubmed	Isolation and characterization of the major gel proteins in human semen, semenogelin I and semenogelin II.	SEMG1 SEMG2	9.38e-06	2	107	2	8665951
Pubmed	Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation.	HIPK1 HIPK2	9.38e-06	2	107	2	20231426
Pubmed	SEMG1/2 augment energy metabolism of tumor cells.	SEMG1 SEMG2	9.38e-06	2	107	2	33311447
Pubmed	Ganglioside GM1 mediates decapacitation effects of SVS2 on murine spermatozoa.	SEMG1 SEMG2	9.38e-06	2	107	2	18753612
Pubmed	Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.	CLASP1 CLASP2	9.38e-06	2	107	2	16866869
Pubmed	Distribution and tissue expression of semenogelin I and II in man as demonstrated by in situ hybridization and immunocytochemistry.	SEMG1 SEMG2	9.38e-06	2	107	2	8833737
Pubmed	The phytoestrogen genistein enhances multidrug resistance in breast cancer cell lines by translational regulation of ABC transporters.	ABCC1 ABCG2	9.38e-06	2	107	2	27033456
Pubmed	Semen-coagulating protein, SVS2, in mouse seminal plasma controls sperm fertility.	SEMG1 SEMG2	9.38e-06	2	107	2	17123940
Pubmed	Golgi-derived CLASP-dependent microtubules control Golgi organization and polarized trafficking in motile cells.	CLASP1 CLASP2	9.38e-06	2	107	2	19701196
Pubmed	Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.	IQGAP2 IQGAP1	9.38e-06	2	107	2	18180285
Pubmed	Evolution of the hominoid semenogelin genes, the major proteins of ejaculated semen.	SEMG1 SEMG2	9.38e-06	2	107	2	14629036
Pubmed	Semenogelin I and II, the predominant human seminal plasma proteins, are also expressed in non-genital tissues.	SEMG1 SEMG2	9.38e-06	2	107	2	12200457
Pubmed	Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans.	SEMG1 SEMG2	9.38e-06	2	107	2	19089943
Pubmed	Quantification of seminal plasma motility inhibitor/semenogelin in human seminal plasma.	SEMG1 SEMG2	9.38e-06	2	107	2	14581514
Pubmed	Gene structure of semenogelin I and II. The predominant proteins in human semen are encoded by two homologous genes on chromosome 20.	SEMG1 SEMG2	9.38e-06	2	107	2	1517240
Pubmed	Mast, a conserved microtubule-associated protein required for bipolar mitotic spindle organization.	CLASP1 CLASP2	9.38e-06	2	107	2	10899121
Pubmed	Expression of MRP1 and ABCG2 is associated with adverse clinical outcomes of papillary thyroid carcinoma with a solid component.	ABCC1 ABCG2	9.38e-06	2	107	2	28411177
Pubmed	Seminal vesicle secretion 2 acts as a protectant of sperm sterols and prevents ectopic sperm capacitation in mice.	SEMG1 SEMG2	9.38e-06	2	107	2	25395676
Pubmed	Hippocampal circAnk3 Deficiency Causes Anxiety-like Behaviors and Social Deficits by Regulating the miR-7080-3p/IQGAP1 Pathway in Mice.	ANK3 IQGAP1	9.38e-06	2	107	2	37913973
Pubmed	The structure of the semenogelin gene locus--nucleotide sequence of the intergenic and the flanking DNA.	SEMG1 SEMG2	9.38e-06	2	107	2	8654389
Pubmed	Seminal vesicle protein SVS2 is required for sperm survival in the uterus.	SEMG1 SEMG2	9.38e-06	2	107	2	24591616
Pubmed	Human Semenogelin 1 Promotes Sperm Survival in the Mouse Female Reproductive Tract.	SEMG1 SEMG2	9.38e-06	2	107	2	32486486
Pubmed	Streamlined platform for short hairpin RNA interference and transgenesis in cultured mammalian cells.	PTBP2 PTBP1	9.38e-06	2	107	2	21768390
Pubmed	Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis.	ABCC1 ABCG2	9.38e-06	2	107	2	18256692
Pubmed	A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons.	PTBP2 PTBP1	9.38e-06	2	107	2	17606642
Pubmed	mRNA expression profile of multidrug resistance genes in childhood acute lymphoblastic leukemia. Low expression levels associated with a higher risk of toxic death.	ABCC1 ABCG2	9.38e-06	2	107	2	19672972
Pubmed	Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.	SEMG1 SEMG2	9.38e-06	2	107	2	22177559
Pubmed	Functional preservation of duplicated pair for RSVS III gene in the REST locus of rat 3q42.	SEMG1 SEMG2	9.38e-06	2	107	2	15582586
Pubmed	The cloning of a rapidly evolving seminal-vesicle-transcribed gene encoding the major clot-forming protein of mouse semen.	SEMG1 SEMG2	9.38e-06	2	107	2	8631362
Pubmed	Expression of semenogelins I and II and its prognostic significance in human prostate cancer.	SEMG1 SEMG2	9.38e-06	2	107	2	21557275
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	KIF13B RANBP2 ACACA IQGAP2 SAE1 VTA1 PRPF6 HEATR1 IQGAP1 EHMT2 NIPBL	1.15e-05	704	107	11	29955894
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	RANBP2 CDC42BPA ACACA HSPA4L RNF213 PTBP1 IQGAP1 RUFY2	1.18e-05	344	107	8	36282215
Pubmed	EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.	TET2 ASZ1 EHMT2	1.25e-05	15	107	3	26576615
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	TET2 ABCC1 RANBP2 VTA1 PRPF6 HEATR1 PTBP1 IQGAP1 TOMM70 JUP ACIN1	1.26e-05	711	107	11	33022573
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	KIF13B CLASP1 HIPK1 CLASP2 ACIN1	1.65e-05	102	107	5	9734811
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	ABCC1 CLASP1 ARHGEF18 RNF213 CLASP2 TFG ABLIM1 TMTC3 UGGT2 CHD6 CORO7	1.68e-05	733	107	11	34672954
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	RANBP2 HSPA4L CLASP2 IQGAP1 ITPR1 LRRC8B CHD6 HERC2 INPP5J	1.68e-05	475	107	9	31040226
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	SEMG2 RANBP2 ACACA CLASP1 RNF213 PRPF6 TFG ERLIN1 TSFM IQGAP1 TOMM70 ABLIM1 JUP ACIN1 CZIB	1.94e-05	1367	107	15	32687490
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	RGPD2 RANBP2 CLASP2 PRPF6 HEATR1 IQGAP1 ACIN1 CDCA7L	1.98e-05	370	107	8	22922362
Pubmed	Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.	ANK3 ITPR1 NIPBL	2.23e-05	18	107	3	33323119
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ACACA ANK3 CLASP1 NAT9 HSPA4L CLASP2 PRPF6 PIK3R4 TRANK1	2.40e-05	497	107	9	36774506
Pubmed	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	NOX5 RNF213 ABCG2	2.65e-05	19	107	3	23118302
Pubmed	MRG15 is required for pre-mRNA splicing and spermatogenesis.	PTBP2 PTBP1	2.81e-05	3	107	2	27573846
Pubmed	Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression.	HIPK2 ITGB4	2.81e-05	3	107	2	19567674
Pubmed	Friend or foe: ABCG2, ABCC1 and ABCB1 expression in triple-negative breast cancer.	ABCC1 ABCG2	2.81e-05	3	107	2	33420675
Pubmed	CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development.	CLASP1 CLASP2	2.81e-05	3	107	2	28285824
Pubmed	Asymmetric CLASP-dependent nucleation of noncentrosomal microtubules at the trans-Golgi network.	CLASP1 CLASP2	2.81e-05	3	107	2	17543864
Pubmed	Enzymatic action of human glandular kallikrein 2 (hK2). Substrate specificity and regulation by Zn2+ and extracellular protease inhibitors.	SEMG1 SEMG2	2.81e-05	3	107	2	10411640
Pubmed	ATP-binding cassette proteins BCRP, MRP1 and P-gp expression and localization in the human umbilical cord.	ABCC1 ABCG2	2.81e-05	3	107	2	26407213
Pubmed	Imaging of activity of multidrug resistance-associated protein 1 in the lungs.	ABCC1 ABCG2	2.81e-05	3	107	2	23596979
Pubmed	Role of ABC-cassette transporters (MDR1, MRP1, BCRP) in the development of primary and acquired multiple drug resistance in patients with early and metastatic breast cancer.	ABCC1 ABCG2	2.81e-05	3	107	2	24382439
Pubmed	CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta.	CLASP1 CLASP2	2.81e-05	3	107	2	16824950
Pubmed	Efflux excretion of bisdemethoxycurcumin-O-glucuronide in UGT1A1-overexpressing HeLa cells: Identification of breast cancer resistance protein (BCRP) and multidrug resistance-associated proteins 1 (MRP1) as the glucuronide transporters.	ABCC1 ABCG2	2.81e-05	3	107	2	30334318
Pubmed	Enzymatic action of prostate-specific antigen (PSA or hK3): substrate specificity and regulation by Zn(2+), a tight-binding inhibitor.	SEMG1 SEMG2	2.81e-05	3	107	2	11027412
Pubmed	Expression of human nPTB is limited by extreme suboptimal codon content.	PTBP2 PTBP1	2.81e-05	3	107	2	18335065
Pubmed	The biology of IQGAP proteins: beyond the cytoskeleton.	IQGAP2 IQGAP1	2.81e-05	3	107	2	25722290
Pubmed	ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in mice.	ABCC1 ABCG2	2.81e-05	3	107	2	22545122
Pubmed	A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions.	ABCC1 ABCG2	2.81e-05	3	107	2	29342177
Pubmed	Polymorphisms in xenobiotic transporters ABCB1, ABCG2, ABCC2, ABCC1, ABCC3 and multiple myeloma risk: a case-control study in the context of the International Multiple Myeloma rESEarch (IMMEnSE) consortium.	ABCC1 ABCG2	2.81e-05	3	107	2	22182917
Pubmed	IQGAP proteins reveal an atypical phosphoinositide (aPI) binding domain with a pseudo C2 domain fold.	IQGAP2 IQGAP1	2.81e-05	3	107	2	22493426
Pubmed	CLIPs and CLASPs and cellular dynamics.	CLASP1 CLASP2	2.81e-05	3	107	2	15928712
Pubmed	Multidrug resistance proteins in gastrointestinal stromal tumors: site-dependent expression and initial response to imatinib.	ABCC1 ABCG2	2.81e-05	3	107	2	16278376
Pubmed	Changes in dipole membrane potential at the mouse blood-brain barrier enhance the transport of 99mTechnetium Sestamibi more than inhibiting Abcb1, Abcc1, or Abcg2.	ABCC1 ABCG2	2.81e-05	3	107	2	19067785
Pubmed	The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr.	PTBP2 PTBP1	2.81e-05	3	107	2	12667457
Pubmed	Involvement of IQGAP family proteins in the regulation of mammalian cell cytokinesis.	IQGAP2 IQGAP1	2.81e-05	3	107	2	25229330
Pubmed	Semenogelin I and semenogelin II, the major gel-forming proteins in human semen, are substrates for transglutaminase.	SEMG1 SEMG2	2.81e-05	3	107	2	9523691
Pubmed	[Correlation of chemosensitivity measured by histoculture drug response assay to expression of multidrug resistance genes and proteins in gastric cancer].	ABCC1 ABCG2	2.81e-05	3	107	2	19622290
Pubmed	Expression and promoter methylation analysis of ATP-binding cassette genes in pancreatic cancer.	ABCC1 ABCG2	2.81e-05	3	107	2	21956451
Pubmed	Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.	ABCC1 ABCG2	2.81e-05	3	107	2	16960658
Pubmed	Promoter methylation patterns of ABCB1, ABCC1 and ABCG2 in human cancer cell lines, multidrug-resistant cell models and tumor, tumor-adjacent and tumor-distant tissues from breast cancer patients.	ABCC1 ABCG2	2.81e-05	3	107	2	27689338
Pubmed	Effect and in silico characterization of genetic variants associated with severe spermatogenic disorders in a large Iberian cohort.	CDC42BPA ABLIM1	2.81e-05	3	107	2	33784440
Pubmed	Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2.	PTBP2 PTBP1	2.81e-05	3	107	2	27791185
Interaction	ECH1 interactions	RANBP2 TRAF1 ACACA CEP128 TSFM IQGAP1 LYRM2 XPNPEP3 HERC2	8.26e-06	253	107	9	int:ECH1
Cytoband	3q12.2	TFG TOMM70	1.92e-04	9	107	2	3q12.2
GeneFamily	Tetratricopeptide repeat domain containing\|Bardet-Biedl syndrome associated\|BBSome	RGPD2 RANBP2 IFIT3 TOMM70 TRANK1 TMTC3	4.23e-06	115	67	6	769
GeneFamily	Cyclic nucleotide gated channels	CNGA1 CNGA4	5.97e-04	10	67	2	250
Coexpression	SESTO_RESPONSE_TO_UV_C5	ABCC1 ITGB4 IQGAP1 PIK3R4 ABLIM1	1.24e-06	46	107	5	M1470
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	ABCC1 TPST1 RANBP2 CDC42BPA CLASP1 CLASP2 GCNT1 REV3L ITPR1 PIK3R4 EVI5 MICAL2 ITSN2 ATP2B1 NIPBL	2.09e-06	856	107	15	M4500
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	ABCC1 RNF213 FMNL3 SH3PXD2A ABCG2 PLA2G4F GPRASP2	1.80e-05	199	107	7	M9184
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	ABCC1 RNF213 TEX15 FMNL3 SH3PXD2A PLA2G4F GPRASP2	1.80e-05	199	107	7	M9180
Coexpression	GSE17721_LPS_VS_CPG_16H_BMDC_DN	ABCC1 ACACA PBK PRPF6 TEX15 TFG PLA2G4F	1.86e-05	200	107	7	M4009
Coexpression	FORTSCHEGGER_PHF8_TARGETS_DN	TRAF1 MYO5B HIPK1 CLASP2 ITGB4 IFIT3 ERLIN1 FBN1 MICAL2 TRIM8 ABCG2 FBXO21 CDCA7L	1.87e-05	783	107	13	M2488
Coexpression	HOFT_CD4_POSITIVE_ALPHA_BETA_MEMORY_T_CELL_BCG_VACCINE_AGE_18_45YO_56D_TOP_100_DEG_AFTER_IN_VITRO_RE_STIMULATION_DN	ABCC1 IFIT3 JUP TRANK1	4.09e-05	47	107	4	M40911
Coexpression	LUI_THYROID_CANCER_CLUSTER_1	ANK3 CLASP1 FBN1 ITSN2	6.11e-05	52	107	4	M2135
Coexpression	LAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB	KIF13B TPST1 CDC42BPA UGGT2 NIPBL CACNA2D3	6.94e-05	169	107	6	M39230
Coexpression	GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP	TRAF1 HIPK1 HIPK2 HEATR1 RUFY2 HERC2	8.15e-05	174	107	6	M6296
Coexpression	GSE27896_HDAC6_KO_VS_WT_TREG_UP	KIF13B HSPA4L ARHGEF18 JUP SYNE3 ATP2B1	8.68e-05	176	107	6	M8248
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	RANBP2 TRAF1 ANK3 HIPK1 RNF213 CLASP2 ABLIM1 NELL2	2.16e-08	192	107	8	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	CDC42BPA IQGAP2 HIPK2 REV3L IQGAP1 TMTC3 TRIM8 NIPBL	2.85e-08	199	107	8	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	ABCC1 RANBP2 TRAF1 ANK3 HIPK1 RNF213 NELL2	1.03e-07	156	107	7	1545169694f686d28648a68b552c2ae606599d66
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	CDC42BPA HIPK2 TFG EVI5 TRIM8 TRAK2 NIPBL	5.17e-07	198	107	7	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TET2 CDC42BPA REV3L TMTC3 ITSN2 TRIM8 NIPBL	5.35e-07	199	107	7	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TET2 RNF213 IFIT3 JUP ITSN2 ACIN1 NIPBL	5.53e-07	200	107	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IQGAP2 ARHGEF18 IQGAP1 ITPR1 NLRP10 DPEP3	2.39e-06	159	107	6	323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RGPD2 TRAF1 ANK3 MYO5B HEATR1 REV3L	2.66e-06	162	107	6	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-STAT1+_Naive_B\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TPST1 PBK IFIT3 BLK CD79B PIF1	3.28e-06	168	107	6	ba127d97697202a8558a0d50bcdafa30b0509de1
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 DPEP3 TRAK2	4.15e-06	175	107	6	e4c9b3c6bde390a3892b112b673f93e118220eb9
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 DPEP3 TRAK2	4.15e-06	175	107	6	4d36da7399c62c170cb603957b35a35efb2c3fbe
ToppCell	LPS-IL1RA-Hematopoietic_Meg-Ery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 DPEP3 TRAK2	4.15e-06	175	107	6	2c39c1b112e873403ad2add8595cc256bf0b97a6
ToppCell	LPS_only-Lymphocytic_B-B_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF18 ITPR1 BLK ABLIM1 CD79B CDCA7L	4.43e-06	177	107	6	c82332c5f656aa26513e4f7525d5d4d733019725
ToppCell	LPS_only-Lymphocytic_B\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF18 ITPR1 BLK ABLIM1 CD79B CDCA7L	4.43e-06	177	107	6	5ed65e08d773d157840317c72e0d43c261d438d4
ToppCell	LPS_only-Lymphocytic_B-B_cells-B-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF18 ITPR1 BLK ABLIM1 CD79B CDCA7L	4.43e-06	177	107	6	8a955a7ab84c434f9ad4b467246b8be3cb479406
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 DPEP3 TRAK2	4.72e-06	179	107	6	7329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 DPEP3 TRAK2	4.72e-06	179	107	6	6e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 DPEP3 TRAK2	4.72e-06	179	107	6	ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RANBP2 TRAF1 HIPK1 RNF213 ITPR1 NIPBL	6.26e-06	188	107	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	RGPD2 RANBP2 HIPK1 BLK FBXO21 ATP2B1	6.85e-06	191	107	6	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCC1 TRAF1 ANK3 ABLIM1 NELL2 TRAK2	7.49e-06	194	107	6	a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA ANK3 CLASP1 PTBP2 CLASP2 VPS54	8.66e-06	199	107	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Meis2-Meis2_Adamts19\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ASZ1 TEX15 GCNT1 CDCA7L	2.32e-05	69	107	4	130b1a56afe6aee01cde56cb983cbc2c41861bb4
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Meis2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ASZ1 TEX15 GCNT1 CDCA7L	2.32e-05	69	107	4	6568fcefcc0dca211f2acf6e4066f795489e758d
ToppCell	PBMC-Control-cDC_1\|Control / Compartment, Disease Groups and Clusters	NOX5 RNF213 IFIT3 TRANK1 TMEM232	3.76e-05	156	107	5	9b6c5bcac516a62bcc1f5be32ffa8c92735ef0bc
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITPR1 BLK SLC34A1 SH3PXD2A CD79B	4.11e-05	159	107	5	74655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	RANBP2 TRAF1 ANK3 ITPR1 NELL2	4.50e-05	162	107	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	normal-na-Lymphocytic_B-B_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RGPD2 BLK TTLL11 ITSN2 CD79B	4.50e-05	162	107	5	ae292318d339305932457bb0e91430594f7a3dfa
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLASP2 TFG ITPR1 BLK ATP2B1	4.63e-05	163	107	5	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF18 BLK SLC34A1 SH3PXD2A CD79B	4.91e-05	165	107	5	22293c6b55f44636440cd737efb786ff5de3373d
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF18 RUFY2 BLK ABLIM1 CD79B	5.05e-05	166	107	5	6a948aefd283a2572da37b59dbc142b6e686b024
ToppCell	facs-Kidney-nan-3m-Lymphocytic-B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF18 RUFY2 BLK ABLIM1 CD79B	5.05e-05	166	107	5	8d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 ARHGEF18 ITPR1 BLK CD79B	5.35e-05	168	107	5	eeb381b62c7ba263af96de1194ed59e57b6ca3ae
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B-B_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 ARHGEF18 ITPR1 BLK CD79B	5.35e-05	168	107	5	063d0368d656962b335154c230bdcd9236e7c9ad
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_B\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 ARHGEF18 ITPR1 BLK CD79B	5.35e-05	168	107	5	a7c4251d8a83bc30196a444028a35c17c24dc291
ToppCell	LPS-IL1RA-Lymphocytic_B-B_cells-B-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 ARHGEF18 ITPR1 BLK CD79B	5.65e-05	170	107	5	92e0873f618b2fa60c4d555b10f234d5cbcf3325
ToppCell	LPS-IL1RA-Lymphocytic_B-B_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 ARHGEF18 ITPR1 BLK CD79B	5.65e-05	170	107	5	c181991f933b779f99afc3782f292306f209e2ac
ToppCell	LPS-IL1RA-Lymphocytic_B\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQGAP2 ARHGEF18 ITPR1 BLK CD79B	5.65e-05	170	107	5	56284fbfd1e53f67c8c0b7fba64505a4002adba2
ToppCell	droplet-Lung-nan-21m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRAF1 MYO5B TXLNB SLC34A1 PLA2G4F	5.81e-05	171	107	5	159ce6d5513008532dd7785b915b3fe7440cc4b2
ToppCell	3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)\|bone_marrow / Manually curated celltypes from each tissue	BLK UGGT2 LRRC8B CDCA7L CACNA2D3	6.14e-05	173	107	5	67f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCell	droplet-Fat-Scat-21m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA CLASP2 FMNL3 JUP ABCG2	6.14e-05	173	107	5	f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCell	LPS-antiTNF-Lymphocytic_B\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF18 ITPR1 BLK ABLIM1 CD79B	6.31e-05	174	107	5	cc493654ea3517bc6a145c7f787f304929636f86
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells-B-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF18 ITPR1 BLK ABLIM1 CD79B	6.31e-05	174	107	5	9eb3504f9340517ef5d056503044fbdb9ffeb714
ToppCell	LPS-antiTNF-Lymphocytic_B-B_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGEF18 ITPR1 BLK ABLIM1 CD79B	6.31e-05	174	107	5	b4c2d1c029fcd0d4926aa79a5b789c713919dcf3
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANK3 MYO5B CLASP2 TRANK1 D2HGDH	6.49e-05	175	107	5	bb898796662b97f7459b7dda7cecf6a9bde8b055
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGEF18 ITPR1 BLK CD79B CDCA7L	6.66e-05	176	107	5	ad05dd934f4ac2e656b3455de091f4c8772de6c8
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B RANBP2 PRPF6 CPED1 TXLNB	6.66e-05	176	107	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFIT3 BLK JUP CD79B CDCA7L	6.66e-05	176	107	5	dde46f06f6fc3f7ba83be91a0ee6231790955e3e
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNF213 IFIT3 TOMM70 TRANK1 THAP12	6.84e-05	177	107	5	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RNF213 IFIT3 TOMM70 TRANK1 THAP12	6.84e-05	177	107	5	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	RNF213 IFIT3 TOMM70 TRANK1 THAP12	6.84e-05	177	107	5	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RNF213 IFIT3 TOMM70 TRANK1 THAP12	6.84e-05	177	107	5	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RNF213 IFIT3 TOMM70 TRANK1 THAP12	6.84e-05	177	107	5	d5aeda113afaa2425874394610344570c9078478
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF13B RANBP2 NUP210L IFIT3 ITSN2	7.03e-05	178	107	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP MICAL2 DPEP3 TRAK2	7.03e-05	178	107	5	eafacc8cd3e986d6ca309e05b6e241331a584fa5
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP MICAL2 DPEP3 TRAK2	7.03e-05	178	107	5	6a5c31e976852edc7d9e899da8e2a1bf23d36759
ToppCell	LPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP MICAL2 DPEP3 TRAK2	7.03e-05	178	107	5	370749834a11d981e9ede26d5f63f0ecb551c015
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-B_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF18 BLK ABLIM1 ITSN2 CD79B	7.61e-05	181	107	5	477c572c5c1efceee49732cc9e8b1dad68a7e6e5
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-B_cell-B_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF18 BLK ABLIM1 ITSN2 CD79B	7.61e-05	181	107	5	909280b44085d8e96fcd3cbcba6bff94badd41e8
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	RANBP2 TRAF1 ANK3 RNF213 NELL2	7.61e-05	181	107	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF18 BLK ABLIM1 ITSN2 CD79B	7.61e-05	181	107	5	ce0e39114bf3bcbcce0fd4c0d70bedadd0853e1d
ToppCell	normal-na-Lymphocytic_B-B_mem-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	MYO5B BLK ITSN2 CD79B ATP2B1	7.81e-05	182	107	5	ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ANK3 IFIT3 TOMM70 ABLIM1 TRANK1	7.81e-05	182	107	5	1aea96ee211f7b9caef7fd385233f51be6021a73
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ANK3 IFIT3 TOMM70 ABLIM1 TRANK1	7.81e-05	182	107	5	b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANK3 IFIT3 TOMM70 ABLIM1 TRANK1	7.81e-05	182	107	5	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANK3 IFIT3 TOMM70 ABLIM1 TRANK1	7.81e-05	182	107	5	4cb182ef39be2044a6ad7266f332d4177591e550
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PBK SAE1 ERLIN1 CHD6 CDCA7L	8.01e-05	183	107	5	ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA GCNT1 ITGB4 TXLNB MICAL2	8.01e-05	183	107	5	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Mild / Disease group, lineage and cell class	ANK3 IFIT3 TOMM70 ABLIM1 TRANK1	8.01e-05	183	107	5	7717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell	(4)_B_cells-(4)_B_mantle\|(4)_B_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	GCNT1 ITPR1 CD79B TRAK2 CDCA7L	8.01e-05	183	107	5	21b7fb6482eb1d5d31a4029e47e0992e8ddc8e2c
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	RNF213 IFIT3 TOMM70 TRANK1 THAP12	8.01e-05	183	107	5	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	343B-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AHSP RUFY2 TRIM8 CD79B LRRC8B	8.01e-05	183	107	5	3cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCell	Immune_cells-large_pre-B.\|World / Lineage and Cell class	PBK SAE1 BLK TTLL11 CD79B	8.01e-05	183	107	5	81b5ed6ed661d2d6a9b807fefd2f0d59bd4ea77e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ABCC1 TRAF1 ANK3 ABLIM1 NELL2	8.22e-05	184	107	5	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	PBMC-Severe-Hematopoietic-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	d685a5a2e525db2eba449cfa1e5cd54eb36162a8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ITPR1 BLK WDR87 CD79B CDCA7L	8.43e-05	185	107	5	3563dd39ec58d3273f95f5bb36b9ccdc0aafb63a
ToppCell	PBMC-Severe-Hematopoietic-RBC\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	5d8d6fd7800f76ee3aa5cef95241d8e6d7e8db04
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	100b5afdf3c6ab07ffc493f7883f5a7b31c59184
ToppCell	COVID-19_Severe-Hematopoietic_R\|COVID-19_Severe / Disease group, lineage and cell class	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	30f064ab7c3890e6f419a845276b145112e78f52
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	f3b1907c3b6f930bc161f46efce5e143babab507
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	44ce50cb99df8ffc50eba311adcf688477618659
ToppCell	PBMC-Severe-Hematopoietic-RBC-RBC-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	17542ccd52a821c9e99b1a7469e80502e764b3fd
ToppCell	Control-Lymphoid-T_Regulatory\|Lymphoid / Disease state, Lineage and Cell class	TET2 ABCC1 TRAF1 VPS54 GCNT1	8.43e-05	185	107	5	e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPA4L ITGB4 JUP TMTC3 SH3PXD2A	8.43e-05	185	107	5	e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell	COVID-19_Severe-Hematopoietic_R-RBC\|COVID-19_Severe / Disease group, lineage and cell class	IFIT3 AHSP MICAL2 ABCG2 TRAK2	8.43e-05	185	107	5	3ed6090b822c6d1d400a421236cddc7511743932
ToppCell	LPS_only-Hematopoietic_Meg-Ery-Erythroid-Erythroid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 TRAK2	8.65e-05	186	107	5	e5014443e9d6e25943308483e20d48b776ae5373
ToppCell	LPS_only-Hematopoietic_Meg-Ery-Erythroid\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 TRAK2	8.65e-05	186	107	5	affc246a1091e44dc85a5e237c778a7541d5a2b4
ToppCell	LPS_only-Hematopoietic_Meg-Ery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HIPK1 AHSP SYNE3 MICAL2 TRAK2	8.65e-05	186	107	5	40d1e15402fdfb3b5ae850a2070cd4b68fda3159
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDC42BPA GCNT1 ITGB4 MICAL2 ABCG2	8.65e-05	186	107	5	5302399825f213d105ac70b91366a4513b732838
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	ARHGEF18 CPED1 BLK CD79B CDCA7L	8.87e-05	187	107	5	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ABCC1 IQGAP1 ITPR1 ABCG2 ATP2B1	8.87e-05	187	107	5	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	IPF-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	ARHGEF18 CPED1 ITPR1 BLK CD79B	8.87e-05	187	107	5	af1327559f7e01bec070881cae52834917c3da65
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-B_cell-B_cell\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HIPK2 JAKMIP3 BLK JUP TXLNB	9.09e-05	188	107	5	99fdd305f75ed38dd507e7a17ffe27c26b86e454
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLASP1 ITPR1 SH3PXD2A INPP5J CACNA2D3	9.09e-05	188	107	5	bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLASP1 ITPR1 SH3PXD2A INPP5J CACNA2D3	9.09e-05	188	107	5	eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-B_cell\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HIPK2 JAKMIP3 BLK JUP TXLNB	9.09e-05	188	107	5	5a0519b189e96001d95f9d24363448e8602b8d4d
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-B_cell-B_cell-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HIPK2 JAKMIP3 BLK JUP TXLNB	9.09e-05	188	107	5	e8b7c1c2eb2e390ad79b358236468b0f15ea58a5
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ANK3 GCNT1 CEP128 IQGAP1 ITPR1	9.09e-05	188	107	5	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IQGAP1 ITPR1 BLK FBXO21 ATP2B1	9.32e-05	189	107	5	b13f315f617840eb5143a4e8a33a657c20365c21
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ITPR1 NELL2 MICAL2 ATP2B1 CACNA2D3	9.32e-05	189	107	5	a75226616340045b581d08429d2e123e041dee55
Drug	Hycanthone [3105-97-3]; Down 200; 11.2uM; HL60; HG-U133A	KIF13B ABCC1 CDC42BPA ITPR1 MICAL2 UGGT2 NIPBL CACNA2D3	2.90e-06	187	107	8	1614_DN
Drug	Catechin-(+,-) hydrate [7295-85-4]; Up 200; 13.8uM; MCF7; HT_HG-U133A	CDC42BPA HIPK2 TEX15 ITGB4 ITPR1 AHSP LRRC8B FBXO21	4.27e-06	197	107	8	3351_UP
Disease	retinal vasculature measurement	CDC42BPA HIPK2 VTA1 ITPR1 SH3PXD2A ACIN1 LRRC8B HERC2	5.31e-04	517	105	8	EFO_0010554
Disease	cerebral cavernous malformation (implicated_via_orthology)	CDC42BPA RNF213	6.76e-04	11	105	2	DOID:0060669 (implicated_via_orthology)
Disease	atopic asthma	TRAF1 TMEM232 EHMT2 THAP12 D2HGDH	7.42e-04	199	105	5	EFO_0010638
Disease	paraxanthine measurement	NOX5 ABCG2	8.09e-04	12	105	2	EFO_0021178
Disease	metabolite measurement	ABCC1 ANK3 DHRS4L1 REV3L SLC34A1 MICAL2 CZIB ABCG2	8.92e-04	560	105	8	EFO_0004725
Disease	bipolar disorder	SEMG1 SEMG2 ANK3 CLASP1 LYRM2 TRANK1 XPNPEP3 TRIM8	1.08e-03	577	105	8	MONDO_0004985
Disease	N-acetylmethionine measurement	ITPR1 MICAL2	1.28e-03	15	105	2	EFO_0021427
Disease	Prostatic Neoplasms	TET2 TRAF1 ASZ1 GCNT1 ITPR1 JUP ITSN2 CHD6	1.63e-03	616	105	8	C0033578
Disease	Malignant neoplasm of prostate	TET2 TRAF1 ASZ1 GCNT1 ITPR1 JUP ITSN2 CHD6	1.63e-03	616	105	8	C0376358
Disease	glutarylcarnitine (C5-DC) measurement	ABCC1 CZIB	1.65e-03	17	105	2	EFO_0800030
Disease	PR interval	KIF13B JUP SYNE3 SH3PXD2A MICAL2 CHD6 THAP12	1.99e-03	495	105	7	EFO_0004462
Disease	HbA1c measurement	TET2 ABCC1 CLASP1 PIPOX PTBP1 RUFY2 JUP ABCG2	2.87e-03	675	105	8	EFO_0004541

Protein segments in the cluster

Peptide	Gene	Start	Entry
MVGKLKQNLLLACLV	TPST1	1	O60507
SALVKRLKGALMLEN	ACIN1	96	Q9UKV3
DLKQQLLLNKLMGKD	ARHGEF18	1266	Q6ZSZ5
GLMSLQLQEALKKQE	CEP128	246	Q6ZU80
QQAFDIMKEAIGKLL	CPED1	321	A4D0V7
QLMKLNSGLGQLILK	ABLIM1	606	O14639
MALLKANKDLISAGL	AHSP	1	Q9NZD4
KQALQKDLNLMAPGL	ERLIN1	151	O75477
ANAVLLLLKRMSKQG	ABCG2	221	Q9UNQ0
KKNLLVTMLIDQLCG	ACACA	1036	Q13085
LSVKQGELQKVILML	EHMT2	656	Q96KQ7
LLKGLNVLDLGLNME	DNHD1	3741	Q96M86
LKQRNTLKDGIIMIQ	CD79B	151	P40259
LTKLAVQIGKAGLLM	ATP2B1	366	P20020
NIVLKLLELGANKML	ASZ1	196	Q8WWH4
NLMDIKIGLLVKNKI	IQGAP1	911	P46940
IKLIKGEAGQNLLEM	RANBP2	331	P49792
IAMKLIKLKLQGQQL	ITSN2	81	Q9NZM3
KAIGLQMALDLLANK	NOX5	686	Q96PH1
VKKVLQRMVGNLLSL	FBXO21	381	O94952
QQVATALMKLKSLGL	HIPK2	306	Q9H2X6
GLVQKIMELQDILAK	NELL2	236	Q99435
ALILNDINPLGKKRM	ITPR1	2076	Q14643
KEQKKLIAMLENGLG	LMOD3	411	Q0VAK6
KGLKVMNLLELVDQL	NLRP10	76	Q86W26
LQQVATALMKLKSLG	HIPK1	296	Q86Z02
IVLLLSKNAGLMQEA	HERC2	1141	O95714
LDINGKALALMIKAV	DHRS4L1	141	P0CG22
QKKEELLNAMVAKLG	CORO7	891	P57737
LALAIGKLGENMILK	TSFM	186	P43897
MKNKNNVTEFILLGL	OR4A15	31	Q8NGL6
AIMGLKELRQQVKDL	EVI5	521	O60447
FANVSQGILLLLMLK	NIPBL	2536	Q6KC79
QGILLLLMLKQHLKN	NIPBL	2541	Q6KC79
LMKKLDILGDNANLT	JAKMIP3	656	Q5VZ66
IKENKAMLAQLLAEL	CDCA7L	221	Q96GN5
ADKMLPLLGAVLLQK	PLA2G4F	11	Q68DD2
LDNLKKMGQNLARVL	ITGB4	146	P16144
LADGLQKMVPLLNKN	JUP	266	P14923
KLQCLLLGKNSLMNL	LRRC8B	726	Q6P9F7
LKSLFEILILMGKQN	THAP12	166	O43422
LILLVKMLNSLLKGQ	SLC34A1	366	Q06495
EIDGLQLVKKLAKNM	CACNA2D3	81	Q8IZS8
QAMIQAAGKLVLIDK	CHD6	776	Q8TD26
GELGDNLKMKIQVLL	FBN1	2856	P35555
QKLKQMLEIILALGN	FMNL3	761	Q8IVF7
DLQMLKGEKLQVLKG	BLK	76	P51451
VLLGLKLQKMNKEAE	IFIT3	211	O14879
ANMVKLLLDRGAKID	ANK3	281	Q12955
QGNMQLKELEKTLAL	LYRM2	71	Q9NU23
LIGVANQKMIELLAD	HEATR1	656	Q9H583
DILQLLKKNGGIVMV	DPEP3	306	Q9H4B8
NLEIVRKLKLLMGEN	GCNT1	226	Q02742
MGKIALQLKATLENI	CZIB	1	Q9NWV4
QLMQQLKALLDPKGI	D2HGDH	496	Q8N465
QLQLILFKVALMLGV	MICAL2	161	O94851
LDLNMDKQGVFTLLK	NUP210L	591	Q5VU65
RIKLMNEILNGIKVL	ABCC1	501	P33527
NKLVCMVKILQATGL	KIF13B	866	Q9NQT8
QLLQLKLGAQVMLVK	PIF1	471	Q9H611
RANLLNMAKLSIKGL	RUFY2	11	Q8WXA3
TNILMLKGKNQAFLE	PTBP2	86	Q9UKA9
LTMLQLKKDLLIGIF	SYNE3	496	Q6ZMZ3
ELMAKLQKLQAAEGK	RNF113B	306	Q8IZP6
IKLIKGEAGQNLLEM	RGPD2	331	P0DJD1
GLKNIANTLMAKALQ	PRPF6	791	O94906
LEKDLNLMDIKIGLL	IQGAP2	821	Q13576
NLMDIKIGLLVKNRI	IQGAP2	826	Q13576
MLLNLSENPAVAKKL	GPRASP2	741	Q96D09
LLLILEKQAAVMGQK	SEMG1	11	P04279
IAKNLILAGVKGLTM	SAE1	51	Q9UBE0
LLLILEKQAAVMGQK	SEMG2	11	Q02383
EGQQLALNKEIMILK	CDC42BPA	726	Q5VT25
KQILMKDGLLDLNIA	CNGA1	596	P29973
ILLKMNKLDVNAEAA	CNGA4	471	Q8IV77
LFVLLTQLLKKMGAD	CLASP1	936	Q7Z460
VLLTQLLKKMGADLL	CLASP2	736	O75122
LLKKMGADLLGSVQA	CLASP2	741	O75122
IGLQEVNSMLNKRLK	INPP5J	461	Q15735
AIAQLLKKLLSQGMT	PIK3R4	766	Q99570
DLVKGKQIAAALMLD	RNF213	521	Q63HN8
GLLQLEMLQEKLKEL	TRAK2	206	O60296
LMKNLKPILLEVNAN	TTLL11	521	Q8NHH1
GIKQLLKDMLAANPQ	STK35	501	Q8TDR2
MLDARQLGLKLIANV	REV3L	2716	O60673
MNGQLDLSGKLIIKA	TFG	1	Q92734
SKLMDQLEALKKQLG	VTA1	61	Q9NP79
ALNDLGKKIQLVMKV	HSPA4L	701	O95757
LALLVLGEAAKLNMA	TMEM232	306	C9JQI7
IGNIMEISNLLNKKA	SH3PXD2A	341	Q5TCZ1
EKVLGKEVLLLMQAL	TXLNGY	91	Q9BZA5
KDQALGKLEQSLRLM	TRAF1	246	Q13077
NQQSMLLADKVLKLL	TOMM70	221	O94826
AIILKVALNMARGLK	PBK	141	Q96KB5
VKNNQLIKDGEMVLL	XPNPEP3	316	Q9NQH7
LIGQKLKDLGIMKNI	XPNPEP3	391	Q9NQH7
GLLLLGMKENQELKT	PIPOX	91	Q9P0Z9
NLLKEIKDILKNMAG	SPZ1	71	Q9BXG8
KILKGLGKEANLLMQ	TXLNB	136	Q8N3L3
LGKEANLLMQNLNKL	TXLNB	141	Q8N3L3
LAIAQKLMELKLGKI	TEX15	356	Q9BXT5
REAQKMAQLLVVLGK	UGGT2	976	Q9NYU1
HIKGLILKGDILMNQ	TMTC3	736	Q6ZXV5
ILKGDILMNQKKDIL	TMTC3	741	Q6ZXV5
KMNLVAINGLLLEAK	TRANK1	2181	O15050
MQEAKKLLGSLQLLF	TRIM8	276	Q9BZR9
NIVLLKNKAVLMPNG	TET2	196	Q6N021
TNLLMLKGKNQAFIE	PTBP1	86	P26599
LGMFNKILAQVEEKL	WDR87	1881	Q6ZQQ6
LQALKGLKDLDLNMA	VPS54	956	Q9P1Q0
IDNVILLMNGALQKK	ATP6V0D2	106	Q8N8Y2
LLMNGALQKKSVKEI	ATP6V0D2	111	Q8N8Y2
LKRLNVGMENKVVQL	MYO5B	916	Q9ULV0
MRLNQNTLLLGKKVV	NAT9	1	Q9BTE0