Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsorting endosome

KDR LDLR

8.70e-056512GO:0097443
GeneOntologyCellularComponentspindle

KNTC1 MAEA PKD2 E4F1 ATM KIF3A KIF11

1.39e-04471517GO:0005819
GeneOntologyCellularComponentaxolemma

EPB41L3 GABBR1

1.19e-0321512GO:0030673
GeneOntologyCellularComponentspindle microtubule

KNTC1 KIF3A KIF11

1.21e-0386513GO:0005876
GeneOntologyCellularComponentcell cortex

MAEA PKD2 TSC1 RAI14 EPB41L2

2.06e-03371515GO:0005938
DomainBand_4.1_C

EPB41L3 EPB41L2

4.37e-054512IPR008379
Domain4_1_CTD

EPB41L3 EPB41L2

4.37e-054512PF05902
DomainSAB_dom

EPB41L3 EPB41L2

4.37e-054512IPR007477
DomainSAB

EPB41L3 EPB41L2

4.37e-054512PF04382
DomainCalx_beta

FREM2 SLC8A1

2.03e-048512SM00237
DomainCalx_beta

FREM2 SLC8A1

2.60e-049512IPR003644
DomainCalx-beta

FREM2 SLC8A1

2.60e-049512PF03160
DomainFERM-adjacent

EPB41L3 EPB41L2

5.59e-0413512IPR014847
DomainFA

EPB41L3 EPB41L2

5.59e-0413512SM01195
DomainFA

EPB41L3 EPB41L2

5.59e-0413512PF08736
DomainCyclophilin-type_PPIase_CS

PPIL3 PPIC

1.21e-0319512IPR020892
DomainEz/rad/moesin-like

EPB41L3 EPB41L2

1.49e-0321512IPR000798
DomainCyclophilin-type_PPIase

PPIL3 PPIC

1.49e-0321512IPR024936
DomainCyclophilin-like_dom

PPIL3 PPIC

1.63e-0322512IPR029000
DomainCSA_PPIASE_2

PPIL3 PPIC

1.63e-0322512PS50072
DomainPro_isomerase

PPIL3 PPIC

1.63e-0322512PF00160
Domain-

PPIL3 PPIC

1.63e-03225122.40.100.10
DomainCyclophilin-type_PPIase_dom

PPIL3 PPIC

1.63e-0322512IPR002130
DomainCSA_PPIASE_1

PPIL3 PPIC

1.63e-0322512PS00170
DomainFERM_CS

EPB41L3 EPB41L2

1.94e-0324512IPR019747
DomainFERM_C

EPB41L3 EPB41L2

2.28e-0326512PF09380
DomainFERM_C

EPB41L3 EPB41L2

2.46e-0327512SM01196
DomainFERM_PH-like_C

EPB41L3 EPB41L2

2.46e-0327512IPR018980
DomainLisH

DCAF1 MAEA

2.64e-0328512SM00667
DomainLisH

DCAF1 MAEA

2.64e-0328512IPR006594
DomainLISH

DCAF1 MAEA

2.64e-0328512PS50896
DomainSNF2_N

SMARCA1 CHD1

3.44e-0332512IPR000330
DomainSNF2_N

SMARCA1 CHD1

3.44e-0332512PF00176
DomainFERM_N

EPB41L3 EPB41L2

3.66e-0333512PF09379
DomainFERM_N

EPB41L3 EPB41L2

3.66e-0333512IPR018979
DomainDEAH_ATP_HELICASE

SMARCA1 CHD1

4.83e-0338512PS00690
DomainKinesin_motor_CS

KIF3A KIF11

5.60e-0341512IPR019821
DomainKinesin-like_fam

KIF3A KIF11

6.15e-0343512IPR027640
DomainKINESIN_MOTOR_1

KIF3A KIF11

6.43e-0344512PS00411
Domain-

KIF3A KIF11

6.43e-03445123.40.850.10
DomainKinesin_motor_dom

KIF3A KIF11

6.43e-0344512IPR001752
DomainKinesin

KIF3A KIF11

6.43e-0344512PF00225
DomainKINESIN_MOTOR_2

KIF3A KIF11

6.43e-0344512PS50067
DomainKISc

KIF3A KIF11

6.43e-0344512SM00129
DomainFERM_M

EPB41L3 EPB41L2

7.01e-0346512PF00373
Domain-

EPB41L3 EPB41L2

7.92e-03495121.20.80.10
DomainFERM_central

EPB41L3 EPB41L2

7.92e-0349512IPR019748
DomainFERM_domain

EPB41L3 EPB41L2

7.92e-0349512IPR000299
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

MYL6 GAPDH SF3A1 EHMT1 RAI14 PC KIF11 SOS1

2.89e-0833351832665550
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZNF131 MYL6 GAPDH SF3A1 TSC1 RAI14 CHD1 EPB41L3 PC EPB41L2 KIF11

8.82e-08934511133916271
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

KNTC1 MYL6 GAPDH SF3A1 SMARCA1 EHMT1 WDR12 CHD1 ATM EPB41L3 PC EPB41L2 KIF11

9.67e-081425511330948266
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

KNTC1 ZNF131 MYL6 GAPDH PPIL3 SF3A1 EHMT1 QRICH1 GMEB2 IFI16 KIF11

4.62e-071103511134189442
Pubmed

Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression.

POSTN KDR

2.11e-06251215082792
Pubmed

Macrophage IKKα Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis.

LDLR CHUK

2.11e-06251226848161
Pubmed

ATM-dependent nuclear accumulation of IKK-alpha plays an important role in the regulation of p73-mediated apoptosis in response to cisplatin.

ATM CHUK

2.11e-06251217700524
Pubmed

Polymorphisms in the KDR and POSTN genes: association with breast cancer susceptibility and prognosis.

POSTN KDR

2.11e-06251216807673
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

MYL6 GAPDH PKD2 ADAMTS20 CHD1 EPB41L3 PC EPB41L2

3.20e-0662151822794259
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

PKD2 TSC1 KIF3A

3.33e-062051317251353
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

ZNF106 QRICH1 GMEB2 EPB41L3 PC IFI16 EPB41L2

3.76e-0644451734795231
Pubmed

IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP.

EHMT1 IFI16

6.32e-06351231682228
Pubmed

Protein 4.1 expression in the developing hair cells of the mouse inner ear.

EPB41L3 EPB41L2

6.32e-06351219853587
Pubmed

Essential function of protein 4.1G in targeting of membrane protein palmitoylated 6 into Schmidt-Lanterman incisures in myelinated nerves.

EPB41L3 EPB41L2

6.32e-06351222025680
Pubmed

[P53-independent apoptosis through a novel ATM/IKK-alpha/p73-mediated apoptotic pathway].

ATM CHUK

6.32e-06351218575226
Pubmed

Isoforms of protein 4.1 are differentially distributed in heart muscle cells: relation of 4.1R and 4.1G to components of the Ca2+ homeostasis system.

EPB41L3 EPB41L2

6.32e-06351222429617
Pubmed

IFI16 induction by glucose restriction in human fibroblasts contributes to autophagy through activation of the ATM/AMPK/p53 pathway.

ATM IFI16

1.26e-05451221573174
Pubmed

Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.

PKD2 KIF3A

1.26e-05451221670265
Pubmed

MicroRNA-21 Aggravates Cyst Growth in a Model of Polycystic Kidney Disease.

PKD2 KIF3A

1.26e-05451226677864
Pubmed

VEGF is crucial for the hepatic vascular development required for lipoprotein uptake.

KDR LDLR

1.26e-05451215944181
Pubmed

Heterozygous mutation of ataxia-telangiectasia mutated gene aggravates hypercholesterolemia in apoE-deficient mice.

ATM LDLR

1.26e-05451215863839
Pubmed

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli.

ATM CHUK

1.26e-05451216497931
Pubmed

Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice.

TSC1 LDLR

1.26e-05451222426206
Pubmed

VEGF receptor inhibition blocks liver cyst growth in pkd2(WS25/-) mice.

PKD2 KDR

1.26e-05451217475663
Pubmed

Cardiac muscle cell cytoskeletal protein 4.1: analysis of transcripts and subcellular location--relevance to membrane integrity, microstructure, and possible role in heart failure.

EPB41L3 EPB41L2

1.26e-05451215834631
Pubmed

16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells.

KDR SOS1

2.10e-05551210319320
Pubmed

Loss of Function Genetic Screen Identifies ATM Kinase as a Positive Regulator of TLR3-Mediated NF-κB Activation.

ATM CHUK

2.10e-05551232731169
Pubmed

Disruption of 14-3-3 binding does not impair Protein 4.1B growth suppression.

EPB41L3 EPB41L2

2.10e-05551215116094
Pubmed

Band 4.1 proteins regulate integrin-dependent cell spreading.

EPB41L3 EPB41L2

2.10e-05551222982319
Pubmed

Monocilia in the embryonic mouse heart suggest a direct role for cilia in cardiac morphogenesis.

PKD2 KIF3A

2.10e-05551218729223
Pubmed

Mechanosensory Genes Pkd1 and Pkd2 Contribute to the Planar Polarization of Brain Ventricular Epithelium.

PKD2 KIF3A

2.10e-05551226245976
Pubmed

Periostin of human periodontal ligament fibroblasts promotes migration of human mesenchymal stem cell through the αvβ3 integrin/FAK/PI3K/Akt pathway.

POSTN GAPDH

2.10e-05551225900259
Pubmed

ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome.

ATM LDLR

2.10e-05551217084711
Pubmed

Cyclin-Dependent Kinase 1 Activity Is a Driver of Cyst Growth in Polycystic Kidney Disease.

PKD2 KIF3A

2.10e-05551233046531
Pubmed

Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage.

ATM IFI16

2.10e-05551230193098
Pubmed

Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.

SLC8A1 PKD2 KDR

2.23e-053751316319116
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DCAF1 GAPDH SMARCA1 TSC1 RAI14 CHD1 EPB41L3 IFI16 EPB41L2 KIF11

2.29e-051353511029467282
Pubmed

The genetic program of hematopoietic stem cells.

ZNF106 ADGRG1 IFI16

2.42e-053851310834841
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

MYL6 SMARCA1 TSC1 RAI14 CHD1 PC IFI16

2.66e-0560151733658012
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

MYL6 PPIL3 SF3A1 EHMT1 WDR12 RAI14 CHD1 IFI16

3.02e-0584751835850772
Pubmed

Loss of cilia suppresses cyst growth in genetic models of autosomal dominant polycystic kidney disease.

PKD2 KIF3A

3.15e-05651223892607
Pubmed

Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis.

TSC1 LDLR

3.15e-05651224687132
Pubmed

ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.

ATM CHUK

3.15e-05651214966265
Pubmed

Ranking novel cancer driving synthetic lethal gene pairs using TCGA data.

KDR ATM

3.15e-05651227438146
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

MYL6 GAPDH PPIL3 SF3A1 TSC1 CHD1 PC LDLR EPB41L2 KIF11

3.35e-051415511028515276
Pubmed

Endothelial primary cilia inhibit atherosclerosis.

PKD2 KIF3A

4.41e-05751226769565
Pubmed

Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene.

FREM2 KDR

4.41e-05751216087869
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 ZNF131 PPIL3 SF3A1 EHMT1 WDR12 CHD1 ATM EPB41L3 EPB41L2

5.10e-051487511033957083
Pubmed

Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail.

DCAF1 ATM

5.87e-05851222184063
Pubmed

Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2.

PKD2 KIF3A

5.87e-05851222983710
Pubmed

3D Mapping Reveals a Complex and Transient Interstitial Matrix During Murine Kidney Development.

POSTN FREM2

5.87e-05851233875569
Pubmed

Structural diversity of band 4.1 superfamily members.

EPB41L3 EPB41L2

5.87e-0585127983158
Pubmed

Temporally compartmentalized expression of ephrin-B2 during renal glomerular development.

KDR TSC1

5.87e-05851211729236
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

MYL6 GAPDH RAI14 PC EPB41L2 KIF11

6.20e-0546851636042349
Pubmed

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway.

TSC1 CHUK

7.54e-05951217693255
Pubmed

Vpr-induced DNA double-strand breaks: molecular mechanism and biological relevance.

DCAF1 ATM

7.54e-05951219275579
Pubmed

Bone marrow-independent adventitial macrophage progenitor cells contribute to angiogenesis.

SLC8A1 KDR

7.54e-05951235264563
Pubmed

PDGF-B signaling is important for murine cardiac development: its role in developing atrioventricular valves, coronaries, and cardiac innervation.

POSTN KDR

7.54e-05951218213589
Pubmed

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.

SMARCA1 CHD1

7.54e-05951216728976
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

MYL6 GAPDH SF3A1 SMARCA1 WDR12 RAI14 IFI16 EPB41L2 KIF11

7.92e-05125751936526897
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ZNF106 WDR12 TSC1 RAI14 ATM EPB41L3

8.63e-0549751636774506
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

DCAF1 ZNF106 MYL6 GAPDH SF3A1 WDR12 CHD1 PC

8.95e-0598951836424410
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

KNTC1 MYL6 GAPDH SF3A1 TSC1 RAI14 CHD1 EPB41L3 EPB41L2

9.31e-05128451917353931
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RAI14 QRICH1 ZNF224 ATM PC KIF3A CHUK FAN1 SOS1

9.36e-05128551935914814
Pubmed

Glyceroneogenesis is the dominant pathway for triglyceride glycerol synthesis in vivo in the rat.

GAPDH PC

9.42e-051051218662986
Pubmed

HIV-1 Vpr: mechanisms of G2 arrest and apoptosis.

DCAF1 ATM

9.42e-051051218514189
Pubmed

Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.

ATM CHUK

9.42e-051051219412180
Pubmed

Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity.

SLC8A1 KDR

9.42e-051051226418893
Pubmed

ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress.

ATM CHUK

9.42e-051051220932476
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

SF3A1 WDR12 E4F1 IFI16 KIF11

1.00e-0431651531665637
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

ZNF106 MYL6 GAPDH EHMT1 WDR12 RAI14 LDLR EPB41L2 KIF11

1.01e-04129751933545068
Pubmed

Functional specialization of beta-arrestin interactions revealed by proteomic analysis.

MYL6 GAPDH EPB41L3 KIF3A CHUK

1.02e-0431751517620599
Pubmed

Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.

PKD2 KIF3A

1.15e-041151227272319
Pubmed

Use of Chuk as an internal standard suitable for quantitative RT-PCR in mouse preimplantation embryos.

GAPDH CHUK

1.15e-041151216984773
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ZNF106 PPIL3 SF3A1 TSC1 CHD1 QRICH1 PC LDLR SOS1

1.20e-04132751932694731
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

SF3A1 SMARCA1 EHMT1 CHD1 GMEB2

1.23e-0433051533301849
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

GAPDH RAI14 EPB41L3 PC KIF11

1.23e-0433051532529326
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ZNF106 SF3A1 ZNF224 ATM IFI16 EPB41L2 SOS1

1.30e-0477451715302935
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MYL6 GAPDH EHMT1 RAI14 EPB41L3 PC EPB41L2

1.33e-0477751735844135
Pubmed

Assignment of the mouse ataxia-telangiectasia gene (Atm) to mouse chromosome 9.

ATM LDLR

1.38e-04125128672141
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

MYL6 GAPDH SF3A1 SMARCA1 WDR12 RAI14 PC SERPINA5 EPB41L2

1.53e-04137151936244648
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

MGAM FREM2 MYL6 GAPDH ADGRG1 MUC5B PPIC SERPINA5

1.54e-04107051823533145
Pubmed

CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy.

POSTN KDR

1.63e-041351222343712
Pubmed

FOXD1 is required for 3D patterning of the kidney interstitial matrix.

POSTN FREM2

1.63e-041351236335435
Pubmed

Mother-Fetus Immune Cross-Talk Coordinates "Extrinsic"/"Intrinsic" Embryo Gene Expression Noise and Growth Stability.

POSTN GAPDH

1.63e-041351236293324
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

DCAF1 ATP7B MYL6 SMARCA1 EHMT1 EPB41L3 LDLR SOS1

2.05e-04111651831753913
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MYL6 P2RX3 GAPDH TSC1 RAI14 EPB41L3 PC EPB41L2 KIF3A

2.10e-04143151937142655
Pubmed

Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.

GAPDH SF3A1 MAEA EPB41L3 PC

2.27e-0437751525147182
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

KNTC1 MYL6 GAPDH SF3A1 MAEA WDR12 QRICH1 EPB41L2 CHUK

2.38e-04145551922863883
Pubmed

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.

WDR12 LDLR

2.50e-041651219198609
Pubmed

Structure-function relationship of Vpr: biological implications.

DCAF1 ATM

2.50e-041651219275588
Pubmed

HIV-1 Vpr-a still "enigmatic multitasker".

DCAF1 ATM

2.50e-041651224744753
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

GAPDH QRICH1 GMEB2 EPB41L3 PPIC EPB41L2

2.57e-0460851616713569
Pubmed

A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses.

WDR12 LDLR

3.18e-041851220971364
Pubmed

LncCMRR Plays an Important Role in Cardiac Differentiation by Regulating the Purb/Flk1 Axis.

SLC8A1 KDR

3.18e-041851236318802
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

ZNF131 SF3A1 SMARCA1 TSC1 CHD1

3.38e-0441151535182466
Pubmed

Isoform-specific GSK3A activity is negatively correlated with human sperm motility.

MYL6 GAPDH MAEA

3.40e-049251330824926
Pubmed

Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.

SMARCA1 RAI14 CHD1 IFI16

3.53e-0422851430471916
Pubmed

TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung.

POSTN KDR

3.55e-041951231870435
Pubmed

Additive effect of multiple genetic variants on the risk of coronary artery disease.

WDR12 LDLR

3.55e-041951220738937
InteractionNUDCD2 interactions

MYL6 GAPDH PPIL3 SF3A1 EHMT1 RAI14 PC KIF11 SOS1

8.66e-07424509int:NUDCD2
InteractionNAA40 interactions

ZNF131 MYL6 GAPDH SF3A1 TSC1 RAI14 CHD1 EPB41L3 PC EPB41L2 KIF11

2.17e-059785011int:NAA40
InteractionSNRNP40 interactions

ZNF131 MYL6 GAPDH SF3A1 SMARCA1 CHD1 QRICH1 GMEB2 EPB41L2

2.34e-05637509int:SNRNP40
InteractionSLFN11 interactions

MYL6 SF3A1 SMARCA1 RAI14 CHD1 LDLR FAN1

3.73e-05376507int:SLFN11
InteractionC5AR1 interactions

ATP7B TMEM245 PKD2 ADGRG1 ATM

3.92e-05154505int:C5AR1
InteractionCEBPA interactions

KNTC1 ZNF131 MYL6 GAPDH PPIL3 SF3A1 EHMT1 CHD1 QRICH1 GMEB2 IFI16 KIF11

3.97e-0512455012int:CEBPA
InteractionTRIM28 interactions

DCAF1 GAPDH SF3A1 MAEA SMARCA1 EHMT1 TSC1 ZNF224 ATM PC IFI16 EPB41L2 KIF11

4.46e-0514745013int:TRIM28
InteractionPOGZ interactions

SMARCA1 EHMT1 KDR TSC1 QRICH1 GMEB2

4.78e-05265506int:POGZ
InteractionHDAC1 interactions

DCAF1 CCDC71 GAPDH SF3A1 EHMT1 RAI14 CHD1 E4F1 ATM EPB41L3 PC

6.80e-0511085011int:HDAC1
InteractionPARP1 interactions

ZNF106 GAPDH SF3A1 SMARCA1 EHMT1 CHD1 E4F1 QRICH1 ATM IFI16 LDLR EPB41L2

6.81e-0513165012int:PARP1
InteractionMDC1 interactions

ZNF106 SF3A1 KDR RAI14 QRICH1 ATM IFI16

6.84e-05414507int:MDC1
InteractionWWC1 interactions

MAEA ATM EPB41L3 EPB41L2

8.67e-0594504int:WWC1
InteractionRICTOR interactions

MYL6 GAPDH SF3A1 TSC1 RAI14 EPB41L3 PC EPB41L2 CHUK

9.11e-05759509int:RICTOR
InteractionE4F1 interactions

E4F1 ATM GMEB2 IFI16

1.15e-04101504int:E4F1
InteractionZBTB2 interactions

SF3A1 SMARCA1 EHMT1 CHD1 GMEB2 EPB41L2 KIF11

1.15e-04450507int:ZBTB2
InteractionPRC1 interactions

MYL6 GAPDH SF3A1 MAEA SMARCA1 WDR12 TSC1 RAI14 CHD1 EPB41L2

1.16e-049735010int:PRC1
InteractionXAGE1A interactions

DCAF1 FREM2 E4F1

1.43e-0441503int:XAGE1A
InteractionEED interactions

DCAF1 KNTC1 CCDC71 MYL6 GAPDH SF3A1 SMARCA1 EHMT1 WDR12 RAI14 LDLR KIF11

1.66e-0414455012int:EED
InteractionTXNIP interactions

DCAF1 GAPDH SMARCA1 KDR EPB41L3

1.77e-04212505int:TXNIP
InteractionH3-3B interactions

SMARCA1 EHMT1 CHD1 KIF3A

1.83e-04114504int:H3-3B
InteractionUSP14 interactions

GAPDH KDR WDR12 RAI14 LDLR EPB41L2 GABBR1

1.92e-04489507int:USP14
InteractionATR interactions

DCAF1 KDR E4F1 ATM CHUK

1.97e-04217505int:ATR
InteractionARL14 interactions

RAI14 EPB41L3 LDLR EPB41L2

2.16e-04119504int:ARL14
InteractionDYNLL1 interactions

DCAF1 GAPDH ATM EPB41L3 PC IFI16 EPB41L2

2.48e-04510507int:DYNLL1
InteractionFOXO3 interactions

TSC1 ATM LDLR CHUK

2.53e-04124504int:FOXO3
Cytoband13q13.3

POSTN FREM2

4.82e-042951213q13.3
CytobandEnsembl 112 genes in cytogenetic band chr13q13

POSTN FREM2

3.80e-0382512chr13q13
CytobandEnsembl 112 genes in cytogenetic band chr3p21

DCAF1 CCDC71 QRICH1

5.27e-03316513chr3p21
Cytoband3p21.31

CCDC71 QRICH1

5.59e-031005123p21.31
CytobandEnsembl 112 genes in cytogenetic band chr2p22

SLC8A1 SOS1

6.03e-03104512chr2p22
GeneFamilyErythrocyte membrane protein band 4.1|FERM domain containing

EPB41L3 EPB41L2

2.18e-054352951
GeneFamilyCyclophilin peptidylprolyl isomerases

PPIL3 PPIC

6.10e-0419352909
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF3A KIF11

3.57e-0346352622
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

EPB41L3 EPB41L2

4.21e-03503521293
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF131 ZNF106 E4F1 ZNF224 ZFP2

1.18e-0271835528
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

KNTC1 ZNF106 SF3A1 TMEM245 ATM SOS1

1.34e-06180516M8239
CoexpressionHALLMARK_MITOTIC_SPINDLE

KNTC1 PKD2 TSC1 EPB41L2 KIF11 SOS1

2.41e-06199516M5893
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

KNTC1 ADGRG1 RAI14 CHD1 ATM EPB41L3 IFI16 KIF3A KIF11

4.34e-06656519M18979
CoexpressionKUMAR_TARGETS_OF_MLL_AF9_FUSION

POSTN GAPDH ATM IFI16 PPIC ZFP2 GABBR1

1.35e-05408517M3284
CoexpressionGSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP

KNTC1 ADGRG1 IFI16 PPIC KIF11

2.36e-05176515M2981
CoexpressionKUMAR_TARGETS_OF_MLL_AF9_FUSION

POSTN GAPDH ATM IFI16 PPIC ZFP2 GABBR1

3.03e-05463517MM1011
CoexpressionGSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_DN

ATP7B MAEA MUC5B EPB41L3 KIF3A

4.04e-05197515M8339
CoexpressionGSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP

POSTN SMARCA1 ZFP2 GABBR1 KIF3A

4.35e-05200515M7022
CoexpressionMARTINEZ_RB1_TARGETS_UP

ZNF106 CCDC71 ADGRG1 WDR12 ATM PC IFI16 KIF11

5.19e-05690518M12224
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

POSTN SLC8A1 PKD2 ADGRG1 RAI14 IFI16 PPIC GABBR1

7.06e-05721518M1999
CoexpressionAtlasFetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2

KNTC1 POSTN ADGRG1 KDR WDR12 PPIC KIF11

4.64e-05410507GSM791122_500
CoexpressionAtlasStem Cells, SC.ST34F.BM, Lineage- cKit+ Sca-1+ flk2- CD34+, Bone marrow, avg-2

KNTC1 PKD2 ADGRG1 WDR12 RAI14 PPIC KIF11

4.71e-05411507GSM791112_500
CoexpressionAtlasFetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3

KNTC1 PKD2 ADGRG1 WDR12 RAI14 PPIC KIF11

5.65e-05423507GSM791126_500
CoexpressionAtlasEB blastocyst_vs_EB amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05

POSTN FREM2 ATP7B KDR IFI16 PPIC

7.13e-05300506PCBC_ratio_EB blastocyst_vs_EB amniotic fluid MSC_cfr-2X-p05
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM FREM2 SLC8A1 ADAMTS20 MUC5B

2.18e-061845152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM FREM2 SLC8A1 ADAMTS20 MUC5B

2.18e-06184515ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM FREM2 SLC8A1 ADAMTS20 MUC5B

2.18e-061845152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCAF1 KDR TSC1 RAI14 EPB41L2

3.05e-06197515789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCellILEUM-inflamed-(7)_ACKR1+_endothelial_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

POSTN ADGRG1 KDR RAI14 PPIC

3.21e-061995155c799115a6e95bcd896e4ad10bd272705c9a4e2c
ToppCellBrain_organoid-organoid_Tanaka_cellReport|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

POSTN ZNF106 SMARCA1 PPIC EPB41L2

3.28e-06200515b0ba486b55be18a4236bd2644f02352651f4b1fe
ToppCellControl-APC-like-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

KNTC1 MGAM SLC8A1 PC

3.38e-05160514463dd624ca5c375b6ff7c269f4ef4b9d74f4b669
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 SLC8A1 EPB41L3 GABBR1

3.63e-051635148dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 SLC8A1 EPB41L3 GABBR1

3.63e-05163514fd243ca223079033be480a24817a399f281fa4d4
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

POSTN MGAM P2RX3 KDR

5.35e-05180514455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDR RAI14 IFI16 GABBR1

5.35e-05180514efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ZNF106 SLC8A1 ADGRG1 ATM

5.58e-05182514c6172aca2475bf0948a78e39f0dae6388504a915
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN KDR IFI16 GABBR1

5.70e-05183514858682df5592c6856487487a7baabd6e60e63a38
ToppCell3'-Adult-SmallIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN KDR IFI16 GABBR1

5.70e-05183514f8212bf8a8b8312434ae030261c558c147f61747
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SLC8A1 CHD1 ATM EPB41L2

6.20e-051875140099def970fbc828756fbf853eca2ce77b8cd342
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAPDH EPB41L3 PC CHUK

6.33e-05188514b483b4629695764568bcbd1d527d614824147783
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GAPDH EPB41L3 PC CHUK

6.33e-05188514c1f64311ff05093b2f4f672e33f5f75e3bc8a8db
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF106 MYL6 PPIC EPB41L2

6.73e-0519151489d03c4133dda852a3713c0902a7d67941cf5b21
ToppCellIPF-Epithelial-Goblet|Epithelial / Disease state, Lineage and Cell class

KDR RAI14 MUC5B LDLR

6.73e-05191514267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN FREM2 MYL6 PPIC

6.87e-05192514d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYL6 GAPDH ADGRG1 IFI16

6.87e-05192514d9e27b8c2fd64e318a399feb5a51283616e1a30c
ToppCellNS-critical-d_07-13-Epithelial-Secretory|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FREM2 ATP7B ADGRG1 PPIC

7.15e-051945142172d951896265243d14996eacce5aab5e14e26e
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN KDR CHD1 PPIC

7.15e-05194514e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FREM2 TMEM245 RAI14 LDLR

7.15e-0519451497534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN ZNF106 MYL6 PPIC

7.29e-05195514bd7526dd80a60ff7bc866e4f5a0e8acdbc10d191
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN FREM2 MYL6 PPIC

7.29e-051955148a04f0e92d10a368ccda5f566ae67ef51f1d34a9
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 EPB41L3 PC LDLR

7.29e-051955143e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC8A1 EPB41L3 PC LDLR

7.29e-051955147796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATP7B ADGRG1 RAI14 PPIC

7.44e-0519651470384c1da9baed843f414cfd1403ddd586a2db07
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG1 KDR PPIC EPB41L2

7.44e-0519651481900dcc9451ff6606ec940c16b559d73247590e
ToppCellcritical-Epithelial-Secretory|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ATP7B ADGRG1 RAI14 PPIC

7.44e-051965147da687eb983a54c28ee990424cc52e01caf5f4aa
ToppCellNS-critical-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGRG1 RAI14 MUC5B PPIC

7.58e-05197514a72047b7428c0d4aaf016c1ac23dc30919260fd8
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN FREM2 MYL6 PPIC

7.58e-051975145a63c2b824c7d0dbbc706e408459c9b9fe65daaa
ToppCellfacs-Tongue-nan-3m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 QRICH1 EPB41L3 PPIC

7.73e-0519851422559b161e67b49fe8028bfaf861e069063599f5
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

ZNF106 ADGRG1 CHD1 SOS1

7.73e-0519851476d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCelltumor_Lung-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

POSTN MYL6 GAPDH RAI14

7.89e-05199514f89d67e3d8cd48ef5c30a5ad71764f4ebbc8bcb3
ToppCell18|World / Age, Tissue, Lineage and Cell class

POSTN MYL6 SMARCA1 PPIC

7.89e-05199514ef043232ee028778b8ddb92aeed7584e2bf586d5
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

POSTN ZNF106 IFI16 EPB41L2

8.04e-052005145ba4ed490c64b3bb738e7729669f893fa73aa56f
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

POSTN ADGRG1 IFI16 LDLR

8.04e-052005142ae62c428728c1d9d4471d4be24bd6ab074fa22c
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ADGRG1 KDR RAI14 IFI16

8.04e-052005142d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

POSTN ADGRG1 PPIC LDLR

8.04e-0520051489eae23195d57f1b23a337ff19c9b8a367e22c96
ToppCellLPS_IL1RA-Endothelial-Endothelial-Vein|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SLC8A1 ADGRG1 RAI14 IFI16

8.04e-05200514b3f93b71589251197cde96b7bc6d065c106f61cd
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

POSTN SLC8A1 SLC38A11 EPB41L2

8.04e-05200514cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCell356C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

POSTN ADGRG1 PPIC LDLR

8.04e-05200514fa99901388eec28004bef85d84f0d7d5bd4df4a8
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

POSTN MYL6 RAI14

8.07e-0573513116259a036373bccaeb77fe3c675741a5ca81c52
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ATP7B SLC5A7 MUC5B

2.72e-04110513b9c8014fd2820e5ea28a7e02fd24227b99e71eb3
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ATP7B SLC5A7 MUC5B

2.72e-04110513ee45592e936d32881c0f3429c21360670e5b3ce3
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-AT1_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

P2RX3 GAPDH ADAMTS20

3.96e-04125513b1a12400f7070bdf09e87974c548a8b82e92b65e
ToppCellLPS-antiTNF-Unknown|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 POSTN KIF11

4.34e-04129513739b263296c28554967362060b154f7a95e1341d
ToppCellBAL-Severe-cDC_6|Severe / Compartment, Disease Groups and Clusters

KNTC1 ATP7B MAEA

4.44e-041305134104d1e10609331b67db3b85c63537aec58b1713
ToppCellLPS-antiTNF-Unknown-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 POSTN KIF11

4.44e-04130513615c233c7c2600c1c2bc5cf5b1c501fc474564ef
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

PKD2 TSC1 ATM

4.95e-04135513ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 ADGRG1 EPB41L3

5.86e-04143513990844ca674d30b2924c74b45bed4fdfb8463fa7
ToppCellClub_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ATP7B SLC5A7 MUC5B

6.60e-0414951381c813588bb5efb7b31141a75d387210dcb76094
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FREM2 SLC8A1 SOS1

6.73e-04150513744050a1b665c6989f37141348af3df7579a73c9
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ATP7B ADAMTS20 MUC5B

6.99e-0415251300d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAM KDR E4F1

6.99e-041525130652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellLPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KNTC1 MGAM ZNF106

7.40e-041555134559e3011514041b65c17ae4ede29da202bce14c
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EPB41L3 PC EPB41L2

7.68e-04157513f896997490bb2eec598c6581f161220e70f9a991
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EPB41L3 PC EPB41L2

7.68e-0415751314a8516346a89a89f1119b744625bd9844a74a03
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 EPB41L3 SERPINA5

7.82e-041585137960337d87afecf2692ab65e5991f052ceddfacc
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POSTN SLC5A7 EPB41L2

8.26e-041615131b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP7B ZFP2 FAN1

8.56e-04163513d2fcd6f561748f7d29a051c504f016952ba32d0f
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN FREM2 MYL6

8.56e-04163513e526104a3a574ee860078ce7c049e7fec9443f37
ToppCellLPS_only-Epithelial_airway-Club_cells-Airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 KDR MUC5B

8.71e-04164513b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCellLPS_only-Epithelial_airway-Club_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 KDR MUC5B

8.71e-04164513c5b2001280a43da855017361a3f6071a0e492848
ToppCellLPS_only-Epithelial_airway|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 KDR MUC5B

8.71e-0416451356e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 KDR MUC5B

9.02e-041665131df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 KDR EPB41L3

9.02e-04166513bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FREM2 KDR MUC5B

9.02e-041665139628522e7af8f8edca733588a364ab2454ac5ca5
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGRG1 PC LDLR

9.02e-04166513575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KNTC1 KDR EPB41L3

9.02e-041665135e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellClub_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MGAM KDR MUC5B

9.18e-04167513dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KNTC1 GMEB2 KIF11

9.34e-041685134c402a1613fcf0a6e4d9b9d5551812940e91ff32
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN PPIL3 SMARCA1

9.50e-041695132d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN PPIL3 SMARCA1

9.50e-04169513ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POSTN PPIL3 SMARCA1

9.50e-04169513ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCellNS-critical-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGRG1 MUC5B PPIC

9.50e-04169513aec97583b23112060437b619cb429dc32f29285f
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

EHMT1 ADGRG1 PC

9.66e-04170513c1f7f1bb8865e954bb499963d82bb51923d5d8d6
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

CHD1 ATM LDLR

9.83e-041715132e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

WDR12 RAI14 KIF11

9.83e-04171513b113fbebb89056af0b9c775d2fb6552206a80467
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG1 KDR FAN1

9.99e-04172513c84cab89c97d647b8a256fd08e33d9102810febd
ToppCellLymphoid-Lymphoid-B_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

GMEB2 LDLR KIF11

9.99e-04172513f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

POSTN IFI16 KIF11

9.99e-04172513ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC38A11 FABP9

1.02e-03173513a2c1ef3f4d7e9f68fc77ee7c42a4727bdea5da94
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC38A11 FABP9

1.02e-031735134830136f1f1976e00ac9af9062a531ac42533041
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDR SLC38A11 FABP9

1.02e-031735130b79e2a4fd19d524c24b69a6b524ffc6affdabe5
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDR RAI14 EPB41L2

1.02e-031735137dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MGAM ATM SOS1

1.02e-0317351336a471576a9d2325066bb14c2f2cd89c67b92915
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POSTN IFI16 GABBR1

1.02e-03173513b57d14e2c2368304cb903562d06ce8228f53857c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MGAM PC SERPINA5

1.02e-03173513922356a5b4c84607318ac24d7caa2e235b72b066
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG1 PPIC LDLR

1.03e-031745130fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGRG1 KDR FABP9

1.03e-03174513b1bcd5f4505d2ccef4183fcfbf1de81964b3f9e0
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG1 PPIC LDLR

1.03e-03174513b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

ZNF131 ZNF106 KIF11

1.05e-03175513c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

POSTN MGAM KIF11

1.05e-031755133e56695a9db97cb1d3503425c48eb79bbf99213e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC8A1 SLC38A11 LDLR

1.07e-03176513b942227abf9902ba13fac6c3e9efb0cacc82af94
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MGAM EPB41L3 PC

1.07e-031765131595dbeee336a81e581325d63208ec6262664ee9
ToppCelltumor_Lung-B_lymphocytes-Plasma_cells|B_lymphocytes / Location, Cell class and cell subclass

KDR PC SERPINA5

1.07e-03176513683022c3400e951b26c2b49394dfd3cc415276fe
ToppCellnucseq-Epithelial-Epithelial_Airway-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KDR RAI14 MUC5B

1.09e-03177513779ba86f53650772755b52460be03f18bb204e55
DrugNPS 1506

MGAM SLC5A7

4.92e-062512CID000156420
DrugGW5638

GAPDH PPIL3 PPIC

1.37e-0521513CID005288494
Drugtetraphenylarsonium thiocyanate

POSTN SERPINA5

1.47e-053512CID006327062
DrugAC1NUTKL

MGAM PPIL3 PPIC

2.07e-0524513CID005426157
DrugAC1O5U0X

PPIL3 KDR PPIC

2.07e-0524513CID006440684
Diseasebrain ischemia (implicated_via_orthology)

SLC8A1 KDR SOS1

2.88e-0535503DOID:2316 (implicated_via_orthology)
DiseaseColorectal Neoplasms

POSTN ATP7B GAPDH KDR CHD1

1.05e-04277505C0009404
DiseaseMouth Neoplasms

ATP7B GAPDH TSC1

1.07e-0454503C0026640
DiseaseMalignant neoplasm of mouth

ATP7B GAPDH TSC1

1.07e-0454503C0153381
Diseasebreast carcinoma (is_marker_for)

ATP7B KDR ATM

1.94e-0466503DOID:3459 (is_marker_for)
Diseasepolycystic kidney disease (implicated_via_orthology)

PKD2 KIF3A

2.53e-0414502DOID:0080322 (implicated_via_orthology)
Diseaseresponse to statin, LDL cholesterol change measurement

LDLR EPB41L2

2.91e-0415502EFO_0007804, GO_0036273
DiseaseNeoplasm of uncertain or unknown behavior of bladder

TSC1 ATM

2.91e-0415502C0496930
DiseaseBenign neoplasm of bladder

TSC1 ATM

2.91e-0415502C0154017
DiseaseCarcinoma in situ of bladder

TSC1 ATM

2.91e-0415502C0154091
DiseaseAdenocarcinoma of lung (disorder)

GAPDH KDR ATM SOS1

4.13e-04206504C0152013
DiseaseCarcinoma of bladder

TSC1 ATM

4.23e-0418502C0699885
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

ATM FAN1

4.72e-0419502C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

ATM FAN1

4.72e-0419502C2936783
Diseasehypertension (biomarker_via_orthology)

POSTN SLC8A1 KDR GABBR1

5.95e-04227504DOID:10763 (biomarker_via_orthology)
DiseaseDyslipidemias

ATP7B LDLR

7.58e-0424502C0242339
DiseaseDyslipoproteinemias

ATP7B LDLR

7.58e-0424502C0598784
Diseaseinflammatory bowel disease (implicated_via_orthology)

EPB41L3 EPB41L2

8.23e-0425502DOID:0050589 (implicated_via_orthology)
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

ATM FAN1

8.91e-0426502C0009405
DiseaseBone Diseases, Developmental

KIF3A CHUK

9.61e-0427502C0005941
DiseaseHereditary non-polyposis colorectal cancer syndrome

ATM FAN1

9.61e-0427502C1112155
Diseasecholesteryl ester 14:0 measurement

SLC38A11 LDLR

9.61e-0427502EFO_0010340
DiseaseHereditary Nonpolyposis Colorectal Cancer

ATM FAN1

1.11e-0329502C1333990
DiseaseColorectal Carcinoma

POSTN ATP7B GAPDH SF3A1 KDR CHD1

1.16e-03702506C0009402
DiseaseSquamous cell carcinoma

GAPDH TSC1 ATM

1.23e-03124503C0007137

Protein segments in the cluster

PeptideGeneStartEntry
VHTLQSMGVDVVLIT

ATP7B

1206

P35670
VIQRMDTTGKTVLHT

CHD1

936

O14646
IEIMVTADAKVVSAH

ADAMTS20

261

P59510
VSVHMEEVVVVTTPD

GMEB2

6

Q9UKD1
VLTVTMVHGKEEGLI

MUC5B

5146

Q9HC84
VMITHGVDVTAQDTT

RAI14

71

Q9P0K7
MVGTTSVVKNSHEEV

QRICH1

361

Q2TAL8
MTTVVVHVDSKAELT

DCAF1

1

Q9Y4B6
HVTMVVAELEKTLSG

MAEA

46

Q7L5Y9
TVDEMTEAVEGHITT

GABBR1

411

Q9UBS5
TEAVEGHITTEIVML

GABBR1

416

Q9UBS5
SDSTEMVKIIVHTVQ

CHUK

581

O15111
VTIHMKETTIDGEEL

KIF11

241

P52732
TLMQKAHTEGVTVVR

MGAM

1621

O43451
IVMEGDKSVITSVHI

FREM2

1076

Q5SZK8
MSVTRVVVHKETELA

EPB41L2

986

O43491
HVLVTLGEKMTEEEV

MYL6

111

P60660
GETTLVKSRHVVMEL

KNTC1

1301

P50748
AVSVDEMRGTITVHK

KIF3A

36

Q9Y496
DVVVPTMEIKVDHTG

ATM

2661

Q13315
MSVVVQHVEEKAVHS

CCDC71

1

Q8IV32
EMVHKAVVEVDESGT

SERPINA5

346

P05154
VHAMEEVVKEVVGHA

FAM25E

111

A8MYX2
AVLMVSSVEVDAVHK

ADGRG1

386

Q9Y653
TGKMEVVVHGRLTTI

IFI16

711

Q16666
EGTQTEVDSHIMKVV

E4F1

661

Q66K89
HIVVTVMVITVATLV

SLC38A11

281

Q08AI6
TVIEMFKSITHSTVG

EHMT1

311

Q9H9B1
VKSTITLENGSMIHV

FABP9

81

Q0Z7S8
DMSVTKVVVHKETEI

EPB41L3

1066

Q9Y2J2
GTSVFVIITKMIVTE

P2RX3

86

P56373
EMAVQDVKHVTITGR

FAN1

771

Q9Y2M0
ATISVIIDVDMHISV

SLC5A7

151

Q9GZV3
TTDEHIVSNSGKMVV

SMARCA1

476

P28370
VVFGKVIDGMTVVHS

PPIC

161

P45877
VEGLMTTVHAITATQ

GAPDH

171

P04406
HIISIERTVKIVMGD

MROH2B

351

Q7Z745
SVKLLGHIEDTVEMT

SOS1

256

Q07889
QVSVIKVKIHEATGM

SF3A1

736

Q15459
KMDTDVVVLTTGVLV

TSC1

121

Q92574
MSVTLHTDVGDIKIE

PPIL3

1

Q9H2H8
VDRMEHSIGSIVSKI

PKD2

846

Q13563
TAKVHQESVHMIEVT

TMEM245

481

Q9H330
TIKAGHVLTIMEVSE

KDR

376

P35968
VTSMTIIEQVGKVHV

ZNF131

466

P52739
QVGVTHKETFTEMRV

ZFP2

31

Q6ZN57
KSIMTIVGHTDVVKD

WDR12

131

Q9GZL7
KIQTEMETVSEAGTH

ZNF224

81

Q9NZL3
ESDIMTTNGVIHVVD

POSTN

611

Q15063
TVRKVHVTKDMTLEG

PC

1156

P11498
HAVTVVNILGKVMVT

ZNF106

1741

Q9H2Y7
TVEIVTMSHQALGDV

LDLR

761

P01130
VTHVSESIGIMEVKV

SLC8A1

546

P32418