Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Kinase-like_dom	SIK1 ALPK1 EIF2AK1	1.22e-02	542	17	3	IPR011009
Domain	WD40	TRAF7 SHKBP1	2.27e-02	259	17	2	PF00400
Pubmed	Proteome-scale Binary Interactomics in Human Cells.	NR0B2 SHKBP1	1.32e-04	33	18	2	27803151
GeneFamily	WD repeat domain containing	TRAF7 SHKBP1	8.72e-03	262	10	2	362
Drug	4-chlorocatechol	LTA4H NT5C SHKBP1	8.31e-07	24	18	3	CID000016496
Drug	AC1L1D89	KY NT5C	1.24e-05	7	18	2	CID000002237
Drug	SC 19220; Down 200; 10uM; PC3; HT_HG-U133A	CHST10 PSMF1 POMT1 GBF1	1.37e-05	192	18	4	7065_DN
Drug	stibium	SIK1 NR0B2 SHKBP1	5.49e-05	95	18	3	CID000023967
Drug	3-chlorocatechol	LTA4H NT5C	1.90e-04	26	18	2	CID000019928
Drug	2,3-dihydroxybiphenyl	LTA4H NT5C	2.20e-04	28	18	2	CID000000254
Drug	4-methylcatechol	LTA4H NT5C	2.71e-04	31	18	2	CID000009958
Drug	Adana	NT5C ALPK1	3.66e-04	36	18	2	CID000117765
Drug	2-chlorobenzoate	LTA4H NT5C	3.66e-04	36	18	2	CID000008374
Drug	deamino-NADP	LTA4H NT5C	4.30e-04	39	18	2	CID000004482
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT_HG-U133A	PHTF2 ALPK1 POMT1	4.52e-04	194	18	3	5216_DN
Drug	Hesperidin [520-26-3]; Down 200; 6.6uM; HL60; HT_HG-U133A	CHST10 POMT1 GBF1	4.66e-04	196	18	3	1294_DN
Drug	N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; HL60; HT_HG-U133A	PHTF2 NT5C GBF1	4.66e-04	196	18	3	3085_DN
Drug	aspirin, USP; Down 200; 100uM; MCF7; HT_HG-U133A	PHTF2 ALPK1 EIF2AK1	4.66e-04	196	18	3	6924_DN
Drug	Nicergoline; Down 200; 8.2uM; PC3; HT_HG-U133A	CHST10 ALPK1 EIF2AK1	4.66e-04	196	18	3	2058_DN
Drug	Telenzepine dihydrochloride [147416-96-4]; Down 200; 9uM; MCF7; HT_HG-U133A	ALPK1 GBF1 EIF2AK1	4.66e-04	196	18	3	5521_DN
Drug	Metyrapone [54-36-4]; Down 200; 17.6uM; HL60; HT_HG-U133A	PHTF2 ALPK1 GBF1	4.73e-04	197	18	3	3070_DN
Drug	Cefalonium [5575-21-3]; Down 200; 8.8uM; MCF7; HT_HG-U133A	PHTF2 NT5C GBF1	4.73e-04	197	18	3	7341_DN
Drug	Piromidic acid [19562-30-2]; Down 200; 13.8uM; PC3; HT_HG-U133A	PHTF2 ALPK1 GBF1	4.73e-04	197	18	3	4575_DN
Drug	haloperidol; Up 200; 10uM; MCF7; HT_HG-U133A	PHTF2 ALPK1 EIF2AK1	4.73e-04	197	18	3	1669_UP
Drug	Todralazine hydrochloride [3778-76-5]; Up 200; 14.8uM; MCF7; HT_HG-U133A	CHST10 ALPK1 EIF2AK1	4.73e-04	197	18	3	1677_UP
Drug	propiconazole	KY SHKBP1	4.75e-04	41	18	2	CID000043234
Drug	Norethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A	PHTF2 ALPK1 EIF2AK1	4.80e-04	198	18	3	7471_UP
Drug	Gabazine [105538-73-6]; Down 200; 10.8uM; HL60; HT_HG-U133A	PHTF2 ALPK1 GBF1	4.80e-04	198	18	3	1316_DN
Drug	Sulfadiazine [68-35-9]; Up 200; 16uM; MCF7; HT_HG-U133A	PHTF2 ALPK1 EIF2AK1	4.80e-04	198	18	3	1688_UP
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; HL60; HT_HG-U133A	CHST10 GBF1 EIF2AK1	4.80e-04	198	18	3	3087_DN
Drug	Pyrazinamide [ 98-96-4]; Down 200; 32.4uM; MCF7; HT_HG-U133A	SIK1 CHST10 ALPK1	4.80e-04	198	18	3	4962_DN
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A	SIK1 CHST10 EIF2AK1	4.80e-04	198	18	3	5220_DN
Drug	Cotinine (-) [486-56-6]; Down 200; 22.6uM; MCF7; HT_HG-U133A	SIK1 CHST10 NT5C	4.80e-04	198	18	3	5611_DN
Drug	Ribavirin [36791-04-5]; Down 200; 16.4uM; HL60; HT_HG-U133A	CHST10 ALPK1 GBF1	4.80e-04	198	18	3	3142_DN
Drug	Ergocryptine-alpha [511-09-1]; Down 200; 7uM; PC3; HT_HG-U133A	CHST10 NT5C ALPK1	4.87e-04	199	18	3	4552_DN
Drug	Sulconazole nitrate [61318-91-0]; Down 200; 8.6uM; PC3; HT_HG-U133A	PHTF2 CHST10 ALPK1	4.87e-04	199	18	3	6652_DN
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; PC3; HT_HG-U133A	PHTF2 GBF1 EIF2AK1	4.87e-04	199	18	3	6308_DN
Drug	HA-1077 dihydrochloride; Up 200; 10uM; PC3; HG-U133A	NR0B2 ALPK1 POMT1	4.94e-04	200	18	3	436_UP
Drug	stibine	LTA4H SHKBP1	5.23e-04	43	18	2	CID000104894
Drug	oxine	NT5C SHKBP1	5.99e-04	46	18	2	CID000001923
Drug	dibenzo-p-dioxin	KY LTA4H	6.25e-04	47	18	2	CID000009216
Drug	2,4-DNT	LTA4H NT5C	7.65e-04	52	18	2	CID000008461
Disease	attention function measurement	CSMD2 PHTF2 LTA4H	7.99e-05	148	17	3	EFO_0007636
Disease	epilepsy	EGFEM1P GBF1	2.53e-04	41	17	2	EFO_0000474
Disease	creatinine measurement, glomerular filtration rate	PHTF2 EGFEM1P	2.04e-03	117	17	2	EFO_0004518, EFO_0005208
Disease	Mental Depression	CSMD2 LTA4H	9.22e-03	254	17	2	C0011570
Disease	Depressive disorder	CSMD2 LTA4H	1.18e-02	289	17	2	C0011581
Disease	household income	CHST10 GBF1	1.30e-02	304	17	2	EFO_0009695

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDYGNHLHCVWLILA	CSMD2	596	Q7Z408
WVHHLHQEEILGRYV	ALPK1	1051	Q96QP1
HHCVGEKYRWVEQHL	NT5C	106	Q8TCD5
WLNEGHTVYLERHIC	LTA4H	316	P09960
IWICHHIEYDIAAAQ	KY	191	Q8NBH2
SHIGHLQQEAHWVLC	NR0B2	186	Q15466
YVLVLGVAAVHAWHL	POMT1	211	Q9Y6A1
GNVVIEHLYHWIHIC	EFCAB5	1451	A4FU69
IVGYHTAWIEHVHVI	EIF2AK1	226	Q9BQI3
VGCVWQTVRDHLYHL	GBF1	1171	Q92538
WYHITVCLDHIFGHN	EGFEM1P	6	Q0D2K5
ALVCFLHWEVVTHGY	PSMF1	21	Q92530
HVHEIFLDCHYNWEL	PHTF2	656	Q8N3S3
VRLVCGHHNWIAVAY	SHKBP1	196	Q8TBC3
WQILSAVEYCHDHHI	SIK1B	131	A0A0B4J2F2
WQILSAVEYCHDHHI	SIK1	131	P57059
WIHVDREVLFCHVHL	MRGPRX1	241	Q96LB2
FGDHIIHWVTYVELC	CHST10	256	O43529
HIVCGTYENLIHVWD	TRAF7	571	Q6Q0C0