Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

MYT1L BCL9L NCOA6 RUVBL1 NCOA1 BCL9 CREBBP MAML3 EP300

5.02e-07303649GO:0003713
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

1.01e-052642GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

1.01e-052642GO:0044017
GeneOntologyMolecularFunctiontranscription coactivator binding

FOXO1 AHR CREBBP EP300

2.69e-0554644GO:0001223
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

3.03e-053642GO:0043993
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA6 CREBBP EP300

4.01e-0521643GO:0042975
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

MYT1L BCL9L TARDBP NCOA6 BNIP1 RUVBL1 GLYR1 IQCB1 NCOA1 BCL9 CREBBP MAML3 EP300

6.58e-0511606413GO:0030674
GeneOntologyMolecularFunctiontranscription coregulator activity

MYT1L BCL9L NCOA6 RUVBL1 NCOA1 BCL9 CREBBP MAML3 EP300

7.21e-05562649GO:0003712
GeneOntologyMolecularFunctionmolecular adaptor activity

MYT1L BCL9L TARDBP NCOA6 BNIP1 SGTB RUVBL1 GLYR1 IQCB1 NCOA1 BCL9 CREBBP MAML3 EP300

7.99e-0513566414GO:0060090
GeneOntologyMolecularFunctionRNA polymerase II general transcription initiation factor binding

RUVBL1 AHR CREBBP

8.69e-0527643GO:0001091
GeneOntologyMolecularFunctionN-acetyltransferase activity

NCOA1 SATL1 CREBBP EP300

1.15e-0478644GO:0008080
GeneOntologyMolecularFunctionN-acyltransferase activity

NCOA1 SATL1 CREBBP EP300

3.22e-04102644GO:0016410
GeneOntologyMolecularFunctionacetyltransferase activity

NCOA1 SATL1 CREBBP EP300

3.47e-04104644GO:0016407
GeneOntologyMolecularFunctionprotein kinase binding

JAK2 SPDYE11 SPDYE17 SPDYE10 SPDYE15 PPP1R9A SPDYE8 SPDYE12 EP300 SPDYE14

4.30e-048736410GO:0019901
GeneOntologyMolecularFunctionTFIID-class transcription factor complex binding

RUVBL1 AHR

4.48e-0410642GO:0001094
GeneOntologyMolecularFunctionhistone acetyltransferase activity

NCOA1 CREBBP EP300

5.86e-0451643GO:0004402
GeneOntologyMolecularFunctionbeta-catenin binding

FOXO1 BCL9L BCL9 EP300

5.97e-04120644GO:0008013
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

NCOA1 CREBBP EP300

7.31e-0455643GO:0061733
GeneOntologyMolecularFunctionpre-mRNA intronic binding

TARDBP EP300

8.98e-0414642GO:0097157
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

NCOA1 CREBBP EP300

9.43e-0460643GO:0034212
GeneOntologyMolecularFunctionkinase binding

JAK2 SPDYE11 SPDYE17 SPDYE10 SPDYE15 PPP1R9A SPDYE8 SPDYE12 EP300 SPDYE14

9.65e-049696410GO:0019900
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

1.03e-0315642GO:0010484
GeneOntologyMolecularFunctiontranscription coregulator binding

FOXO1 AHR CREBBP EP300

1.06e-03140644GO:0001221
GeneOntologyMolecularFunctiongeneral transcription initiation factor binding

RUVBL1 AHR CREBBP

1.14e-0364643GO:0140296
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

RUVBL1 AHR CREBBP

1.24e-0366643GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

RUVBL1 AHR CREBBP

1.24e-0366643GO:0001098
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NCOA6 EP300

1.85e-0320642GO:0035259
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

NCOA6 WWP2 AHR NCOA1 CREBBP EP300

2.16e-03417646GO:0061629
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOA6 NCOA1

2.45e-0323642GO:0046965
GeneOntologyMolecularFunctiontranscription factor binding

FOXO1 NCOA6 RUVBL1 WWP2 AHR NCOA1 CREBBP EP300

2.70e-03753648GO:0008134
GeneOntologyMolecularFunctionTBP-class protein binding

RUVBL1 AHR

5.01e-0333642GO:0017025
GeneOntologyMolecularFunctionphosphatidylcholine binding

CHMP3 CHMP2A

5.31e-0334642GO:0031210
GeneOntologyMolecularFunctionhistone modifying activity

JAK2 NCOA1 CREBBP EP300

6.25e-03229644GO:0140993
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300

6.27e-0337642GO:0043425
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

NCOA1 SATL1 CREBBP EP300

7.15e-03238644GO:0016747
GeneOntologyMolecularFunctionchromatin-protein adaptor activity

NCOA6 GLYR1

7.65e-0341642GO:0140463
GeneOntologyBiologicalProcessvesicle fusion with vacuole

CHMP3 CHMP2A CHMP2B

5.61e-0613573GO:0051469
GeneOntologyBiologicalProcessmultivesicular body-lysosome fusion

CHMP3 CHMP2A CHMP2B

5.61e-0613573GO:0061763
GeneOntologyBiologicalProcessvacuole fusion

CHMP3 CHMP2A CHMP2B

7.13e-0614573GO:0097576
GeneOntologyBiologicalProcessviral budding from plasma membrane

CHMP3 CHMP2A CHMP2B

7.13e-0614573GO:0046761
GeneOntologyBiologicalProcessnon-lytic viral release

CHMP3 CHMP2A CHMP2B

8.89e-0615573GO:0046753
GeneOntologyBiologicalProcessnuclear membrane organization

TARDBP CHMP3 CHMP2A CHMP2B

9.31e-0648574GO:0071763
GeneOntologyBiologicalProcesslysosomal membrane organization

CHMP3 CHMP2A CHMP2B

1.59e-0518573GO:0097212
GeneOntologyBiologicalProcessendosome to lysosome transport via multivesicular body sorting pathway

CHMP3 CHMP2A CHMP2B

1.88e-0519573GO:0032510
GeneOntologyBiologicalProcessmidbody abscission

CHMP3 CHMP2A CHMP2B

1.88e-0519573GO:0061952
GeneOntologyBiologicalProcessnuclear envelope organization

TARDBP CHMP3 CHMP2A CHMP2B

2.76e-0563574GO:0006998
GeneOntologyBiologicalProcessregulation of secretion by cell

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3 PPP1R9A CHMP3 CHMP2A EP300

3.12e-057405710GO:1903530
GeneOntologyBiologicalProcesslate endosome to lysosome transport

CHMP3 CHMP2A CHMP2B

3.41e-0523573GO:1902774
GeneOntologyBiologicalProcessviral budding via host ESCRT complex

CHMP3 CHMP2A CHMP2B

3.41e-0523573GO:0039702
GeneOntologyBiologicalProcessregulation of mitotic spindle assembly

CHMP3 CHMP2A CHMP2B

3.89e-0524573GO:1901673
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

4.49e-054572GO:0018076
GeneOntologyBiologicalProcessorganelle membrane fusion

BNIP1 CPLX3 CHMP3 CHMP2A CHMP2B

4.84e-05144575GO:0090174
GeneOntologyBiologicalProcessbiological process involved in symbiotic interaction

TARDBP PI4KA WWP2 CHMP3 CHMP2A EP300 CHMP2B

4.96e-05351577GO:0044403
GeneOntologyBiologicalProcessviral budding

CHMP3 CHMP2A CHMP2B

4.97e-0526573GO:0046755
GeneOntologyBiologicalProcessnuclear membrane reassembly

CHMP3 CHMP2A CHMP2B

4.97e-0526573GO:0031468
GeneOntologyBiologicalProcessregulation of secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3 PPP1R9A CHMP3 CHMP2A EP300

6.08e-058015710GO:0051046
GeneOntologyBiologicalProcessviral release from host cell

CHMP3 CHMP2A CHMP2B

7.70e-0530573GO:0019076
GeneOntologyBiologicalProcessexit from host cell

CHMP3 CHMP2A CHMP2B

7.70e-0530573GO:0035891
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

MYT1L FOXO1 JAK2 BCL9L NCOA6 WWP2 AHR NCOA1 BCL9 CREBBP MAML3 EP300 CREB5

8.38e-0513905713GO:0045944
GeneOntologyBiologicalProcessmitotic cytokinetic process

CHMP3 CHMP2A CHMP2B

1.03e-0433573GO:1902410
GeneOntologyBiologicalProcessmultivesicular body assembly

CHMP3 CHMP2A CHMP2B

1.03e-0433573GO:0036258
GeneOntologyBiologicalProcesssecretion

FOXO1 JAK2 TARDBP NCOA6 CAD ABCA12 CPLX3 PPP1R9A CHMP3 NCOA1 CHMP2A EP300

1.04e-0412215712GO:0046903
GeneOntologyBiologicalProcessnucleus organization

TARDBP IFT88 CHMP3 CHMP2A CHMP2B

1.06e-04170575GO:0006997
GeneOntologyBiologicalProcessinsulin secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3

1.07e-04274576GO:0030073
GeneOntologyBiologicalProcessplasma membrane repair

CHMP3 CHMP2A CHMP2B

1.13e-0434573GO:0001778
GeneOntologyBiologicalProcessmultivesicular body organization

CHMP3 CHMP2A CHMP2B

1.13e-0434573GO:0036257
GeneOntologyBiologicalProcessregulation of spindle assembly

CHMP3 CHMP2A CHMP2B

1.13e-0434573GO:0090169
GeneOntologyBiologicalProcessvirion assembly

CHMP3 CHMP2A CHMP2B

1.23e-0435573GO:0019068
GeneOntologyBiologicalProcessubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

CHMP3 CHMP2A CHMP2B

1.45e-0437573GO:0043162
GeneOntologyBiologicalProcesspost-embryonic hemopoiesis

JAK2 AHR

1.56e-047572GO:0035166
GeneOntologyBiologicalProcesslate endosome to vacuole transport

CHMP3 CHMP2A CHMP2B

1.70e-0439573GO:0045324
GeneOntologyBiologicalProcessorganelle fusion

BNIP1 CPLX3 CHMP3 CHMP2A CHMP2B

1.79e-04190575GO:0048284
GeneOntologyBiologicalProcessendosome organization

UBR4 CHMP3 CHMP2A CHMP2B

2.11e-04106574GO:0007032
GeneOntologyBiologicalProcessendosome transport via multivesicular body sorting pathway

CHMP3 CHMP2A CHMP2B

2.28e-0443573GO:0032509
GeneOntologyBiologicalProcessregulation of mitotic spindle organization

CHMP3 CHMP2A CHMP2B

2.45e-0444573GO:0060236
GeneOntologyBiologicalProcessviral process

TARDBP WWP2 CHMP3 CHMP2A CREBBP EP300 CHMP2B

2.79e-04464577GO:0016032
GeneOntologyBiologicalProcesspositive regulation of protein localization to nucleus

JAK2 TARDBP CREBBP EP300

2.79e-04114574GO:1900182
GeneOntologyBiologicalProcessmembrane fusion

BNIP1 CPLX3 CHMP3 CHMP2A CHMP2B

2.90e-04211575GO:0061025
GeneOntologyBiologicalProcesspeptide hormone secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3

3.12e-04334576GO:0030072
GeneOntologyBiologicalProcesscytokinetic process

CHMP3 CHMP2A CHMP2B

3.17e-0448573GO:0032506
GeneOntologyBiologicalProcessmembrane fission

CHMP3 CHMP2A CHMP2B

3.17e-0448573GO:0090148
GeneOntologyBiologicalProcessregulation of spindle organization

CHMP3 CHMP2A CHMP2B

3.17e-0448573GO:0090224
GeneOntologyBiologicalProcessESCRT III complex disassembly

CHMP2A CHMP2B

3.33e-0410572GO:1904903
GeneOntologyBiologicalProcessESCRT complex disassembly

CHMP2A CHMP2B

3.33e-0410572GO:1904896
GeneOntologyBiologicalProcessprotein secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3 EP300

3.42e-04480577GO:0009306
GeneOntologyBiologicalProcessestablishment of protein localization to extracellular region

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3 EP300

3.55e-04483577GO:0035592
GeneOntologyBiologicalProcesspeptide secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3

3.60e-04343576GO:0002790
GeneOntologyBiologicalProcessmultivesicular body sorting pathway

CHMP3 CHMP2A CHMP2B

3.79e-0451573GO:0071985
GeneOntologyBiologicalProcessspindle organization

CHMP3 HAUS2 TTK CHMP2A CHMP2B

3.82e-04224575GO:0007051
GeneOntologyBiologicalProcessprotein localization to extracellular region

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3 EP300

3.87e-04490577GO:0071692
GeneOntologyBiologicalProcessregulation of protein secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12 EP300

4.00e-04350576GO:0050708
GeneOntologyBiologicalProcessregulation of centrosome duplication

CHMP3 CHMP2A CHMP2B

4.02e-0452573GO:0010824
GeneOntologyBiologicalProcesspeptide transport

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3

4.32e-04355576GO:0015833
GeneOntologyBiologicalProcessregulation of insulin secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12

4.40e-04231575GO:0050796
GeneOntologyBiologicalProcessDNA-templated transcription initiation

FOXO1 NCOA6 GLYR1 AHR EP300

4.40e-04231575GO:0006352
GeneOntologyBiologicalProcesspositive regulation of protein import into nucleus

JAK2 TARDBP EP300

4.49e-0454573GO:0042307
GeneOntologyBiologicalProcesspyrimidine ribonucleoside monophosphate biosynthetic process

CAD DCK

4.86e-0412572GO:0009174
GeneOntologyBiologicalProcesssecretion by cell

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3 PPP1R9A CHMP3 CHMP2A EP300

6.04e-0410645710GO:0032940
GeneOntologyBiologicalProcessvesicle fusion

CPLX3 CHMP3 CHMP2A CHMP2B

6.41e-04142574GO:0006906
GeneOntologyBiologicalProcessresponse to ketone

JAK2 CAD AHR NCOA1 EP300

6.76e-04254575GO:1901654
GeneOntologyBiologicalProcessregulation of centrosome cycle

CHMP3 CHMP2A CHMP2B

7.06e-0463573GO:0046605
GeneOntologyBiologicalProcessmembrane assembly

CHMP3 CHMP2A CHMP2B

7.40e-0464573GO:0071709
GeneOntologyBiologicalProcessmitotic metaphase chromosome alignment

CHMP3 CHMP2A CHMP2B

7.74e-0465573GO:0007080
GeneOntologyBiologicalProcessmitotic spindle organization

CHMP3 TTK CHMP2A CHMP2B

8.07e-04151574GO:0007052
GeneOntologyBiologicalProcessspindle assembly

CHMP3 HAUS2 CHMP2A CHMP2B

8.47e-04153574GO:0051225
GeneOntologyBiologicalProcessregulation of protein transport

FOXO1 JAK2 TARDBP NCOA6 ABCA12 WWP2 EP300

8.55e-04560577GO:0051223
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

CREBBP EP300

8.78e-0416572GO:0006474
GeneOntologyBiologicalProcessregulation of cellular response to heat

CREBBP EP300

8.78e-0416572GO:1900034
GeneOntologyBiologicalProcessprotein acetylation

FOXO1 CREBBP EP300

8.83e-0468573GO:0006473
GeneOntologyBiologicalProcessautophagosome maturation

CHMP3 CHMP2A CHMP2B

9.21e-0469573GO:0097352
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

BCL9L TNRC6C BCL9 CREBBP EP300

9.82e-04276575GO:0007179
GeneOntologyBiologicalProcesspyrimidine ribonucleoside monophosphate metabolic process

CAD DCK

9.94e-0417572GO:0009173
GeneOntologyBiologicalProcessregulation of peptide hormone secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12

9.98e-04277575GO:0090276
GeneOntologyBiologicalProcessamide transport

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3

1.04e-03420576GO:0042886
GeneOntologyBiologicalProcesshormone secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3

1.04e-03420576GO:0046879
GeneOntologyBiologicalProcesspositive regulation of intracellular transport

JAK2 TARDBP ABCA12 EP300

1.05e-03162574GO:0032388
GeneOntologyBiologicalProcessregulation of peptide transport

FOXO1 JAK2 TARDBP NCOA6 ABCA12

1.08e-03282575GO:0090087
GeneOntologyBiologicalProcessregulation of peptide secretion

FOXO1 JAK2 TARDBP NCOA6 ABCA12

1.08e-03282575GO:0002791
GeneOntologyBiologicalProcessmembrane biogenesis

CHMP3 CHMP2A CHMP2B

1.09e-0373573GO:0044091
GeneOntologyBiologicalProcesscentrosome cycle

CHMP3 HAUS2 CHMP2A CHMP2B

1.10e-03164574GO:0007098
GeneOntologyBiologicalProcessexport from cell

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3 PPP1R9A CHMP3 CHMP2A EP300

1.12e-0311535710GO:0140352
GeneOntologyBiologicalProcesshormone transport

FOXO1 JAK2 TARDBP NCOA6 ABCA12 CPLX3

1.20e-03432576GO:0009914
GeneOntologyBiologicalProcesspositive regulation of cell size

AHR EP300

1.24e-0319572GO:0045793
GeneOntologyBiologicalProcesspyrimidine nucleoside monophosphate biosynthetic process

CAD DCK

1.24e-0319572GO:0009130
GeneOntologyBiologicalProcesspositive regulation of nucleocytoplasmic transport

JAK2 TARDBP EP300

1.36e-0379573GO:0046824
GeneOntologyBiologicalProcessregulation of exosomal secretion

CHMP3 CHMP2A

1.38e-0320572GO:1903541
GeneOntologyBiologicalProcessregulation of protein localization to nucleus

JAK2 TARDBP CREBBP EP300

1.42e-03176574GO:1900180
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

CHMP3 HAUS2 CHMP2A CHMP2B

1.42e-03176574GO:0070507
GeneOntologyBiologicalProcessregulation of protein import into nucleus

JAK2 TARDBP EP300

1.47e-0381573GO:0042306
GeneOntologyBiologicalProcesscentrosome duplication

CHMP3 CHMP2A CHMP2B

1.47e-0381573GO:0051298
GeneOntologyBiologicalProcessmicrotubule organizing center organization

CHMP3 HAUS2 CHMP2A CHMP2B

1.51e-03179574GO:0031023
GeneOntologyBiologicalProcessendosome to lysosome transport

CHMP3 CHMP2A CHMP2B

1.63e-0384573GO:0008333
GeneOntologyBiologicalProcessregulation of intracellular transport

JAK2 TARDBP ABCA12 CHMP3 EP300

1.74e-03314575GO:0032386
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase II promoter

FOXO1 GLYR1 AHR EP300

1.74e-03186574GO:0006367
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization involved in mitosis

CHMP3 TTK CHMP2A CHMP2B

1.78e-03187574GO:1902850
GeneOntologyBiologicalProcessstimulatory C-type lectin receptor signaling pathway

CREBBP EP300

1.83e-0323572GO:0002223
GeneOntologyCellularComponentamphisome membrane

CHMP3 CHMP2A CHMP2B

5.11e-0613563GO:1904930
GeneOntologyCellularComponentESCRT III complex

CHMP3 CHMP2A CHMP2B

6.49e-0614563GO:0000815
GeneOntologyCellularComponentamphisome

CHMP3 CHMP2A CHMP2B

8.10e-0615563GO:0044753
GeneOntologyCellularComponenttranscription regulator complex

BCL9L NCOA6 DACH2 DACH1 AHR NCOA1 BCL9 CREBBP EP300

2.69e-05596569GO:0005667
GeneOntologyCellularComponentkinetochore microtubule

CHMP3 CHMP2A CHMP2B

2.70e-0522563GO:0005828
GeneOntologyCellularComponentmultivesicular body membrane

CHMP3 CHMP2A CHMP2B

7.02e-0530563GO:0032585
GeneOntologyCellularComponentspindle microtubule

CHMP3 HAUS2 CHMP2A CHMP2B

8.33e-0586564GO:0005876
GeneOntologyCellularComponentESCRT complex

CHMP3 CHMP2A CHMP2B

8.55e-0532563GO:0036452
GeneOntologyCellularComponentkinetochore

CHMP3 TTK CHMP2A CREBBP CHMP2B

1.23e-04181565GO:0000776
GeneOntologyCellularComponentcondensed chromosome, centromeric region

CHMP3 TTK CHMP2A CREBBP CHMP2B

1.66e-04193565GO:0000779
GeneOntologyCellularComponentchromatin

MYT1L FOXO1 JAK2 TARDBP RUVBL1 GLYR1 AHR NCOA1 CHMP2A CREBBP EP300 CREB5

4.57e-0414805612GO:0000785
GeneOntologyCellularComponentautophagosome membrane

CHMP3 CHMP2A CHMP2B

4.81e-0457563GO:0000421
GeneOntologyCellularComponentbeta-catenin-TCF complex

BCL9L BCL9

5.39e-0413562GO:1990907
GeneOntologyCellularComponentchromosome, centromeric region

CHMP3 TTK CHMP2A CREBBP CHMP2B

8.53e-04276565GO:0000775
GeneOntologyCellularComponentsperm head-tail coupling apparatus

FSIP2 IFT88

1.05e-0318562GO:0120212
GeneOntologyCellularComponentcondensed chromosome

CHMP3 TTK CHMP2A CREBBP CHMP2B

1.37e-03307565GO:0000793
GeneOntologyCellularComponentspindle

IQCB1 CHMP3 HAUS2 TTK CHMP2A CHMP2B

1.59e-03471566GO:0005819
GeneOntologyCellularComponentmultivesicular body

CHMP3 CHMP2A CHMP2B

1.70e-0388563GO:0005771
GeneOntologyCellularComponenthistone acetyltransferase complex

RUVBL1 CREBBP EP300

2.05e-0394563GO:0000123
GeneOntologyCellularComponentnuclear pore

CHMP3 CHMP2A CHMP2B

2.52e-03101563GO:0005643
GeneOntologyCellularComponentprotein acetyltransferase complex

RUVBL1 CREBBP EP300

2.74e-03104563GO:0031248
GeneOntologyCellularComponentacetyltransferase complex

RUVBL1 CREBBP EP300

3.13e-03109563GO:1902493
GeneOntologyCellularComponentnuclear protein-containing complex

BCL9L NCOA6 RUVBL1 AHR CHMP3 NCOA1 BCL9 CHMP2A CREBBP CHMP2B

3.28e-0313775610GO:0140513
GeneOntologyCellularComponentGolgi-associated vesicle

BNIP1 PI4KA DOP1A

3.55e-03114563GO:0005798
GeneOntologyCellularComponentautophagosome

CHMP3 CHMP2A CHMP2B

4.00e-03119563GO:0005776
GeneOntologyCellularComponentchromosomal region

CHMP3 TTK CHMP2A CREBBP CHMP2B

5.32e-03421565GO:0098687
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

BCL9L NCOA1 BCL9 CREBBP

6.06e-03272564GO:0090575
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

1.32e-052192HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

1.32e-052192HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

1.32e-052192HP:0001042
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

3.95e-053192HP:0008752
HumanPhenoPhobia

CREBBP EP300

3.95e-053192HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

3.95e-053192HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

3.95e-053192HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

3.95e-053192HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

3.95e-053192HP:0005895
HumanPhenoTrichiasis

CREBBP EP300

7.87e-054192HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

7.87e-054192HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

7.87e-054192HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

7.87e-054192HP:0006200
HumanPhenoVascular ring

CREBBP EP300

7.87e-054192HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

7.87e-054192HP:0031207
HumanPhenoPapillary cystadenoma of the epididymis

CREBBP EP300

1.31e-045192HP:0009715
HumanPhenoSupernumerary cusp

CREBBP EP300

1.31e-045192HP:0033777
HumanPhenoEpididymal neoplasm

CREBBP EP300

1.31e-045192HP:0030421
HumanPhenoSensory behavioral abnormality

MYT1L IFT88 KLHL7 AHR CREBBP EP300 CHMP2B

1.31e-04337197HP:5200046
HumanPhenoLarge foramen magnum

CREBBP EP300

1.96e-046192HP:0002700
HumanPhenoAspiration

PI4KA CREBBP EP300

2.45e-0434193HP:0002835
HumanPhenoDyspnea

MYT1L JAK2 TARDBP KLHL7 SRP54 CREBBP EP300 CHMP2B

2.52e-04506198HP:0002094
HumanPhenoDeviated nasal septum

CREBBP EP300

2.74e-047192HP:0004411
HumanPhenoPilomatrixoma

CREBBP EP300

4.67e-049192HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

4.67e-049192HP:0002341
HumanPhenoFrontal hirsutism

CREBBP EP300

5.83e-0410192HP:0011335
HumanPhenoHoffmann sign

TARDBP PI4KA CHMP2B

6.04e-0446193HP:0031993
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

7.11e-0411192HP:0031251
HumanPhenoKeratoconus

IFT88 KLHL7 IQCB1 AHR

7.85e-04117194HP:0000563
HumanPhenoSelf-mutilation

MYT1L CREBBP EP300

8.18e-0451193HP:0000742
HumanPhenoIncreased corneal curvature

IFT88 KLHL7 IQCB1 AHR

8.63e-04120194HP:0100692
MousePhenothin myocardium compact layer

NCOA6 SHROOM3 CREBBP EP300

1.51e-0546464MP:0004057
MousePhenothin ventricle myocardium compact layer

SHROOM3 CREBBP EP300

3.66e-0520463MP:0010556
MousePhenoabnormal myocardium compact layer morphology

NCOA6 SHROOM3 CREBBP EP300

6.76e-0567464MP:0004056
MousePhenoventricle myocardium hypoplasia

NCOA6 SHROOM3 CREBBP EP300

8.49e-0571464MP:0010502
MousePhenomyocardium hypoplasia

NCOA6 SHROOM3 CREBBP EP300

1.79e-0486464MP:0010500
MousePhenoabnormal megakaryocyte morphology

JAK2 SMAP1 CREBBP EP300

1.79e-0486464MP:0002417
MousePhenoabsent organized vascular network

FOXO1 CREBBP

2.93e-048462MP:0000263
MousePhenoventricular hypoplasia

NCOA6 SHROOM3 CREBBP EP300

3.07e-0499464MP:0000279
MousePhenoabnormal erythroid progenitor cell morphology

JAK2 SMAP1 NCOA6 DCK

3.19e-04100464MP:0008801
MousePhenoabnormal bone marrow hematopoietic cell morphology

JAK2 SMAP1 CREBBP EP300

3.45e-04102464MP:0013660
MousePhenoheart hypoplasia

NCOA6 SHROOM3 CREBBP EP300

3.58e-04103464MP:0002740
MousePhenoincreased megakaryocyte cell number

JAK2 CREBBP EP300

4.30e-0445463MP:0008254
MousePhenoincreased erythroid progenitor cell number

JAK2 SMAP1 DCK

4.30e-0445463MP:0003135
MousePhenoabnormal precentral gyrus morphology

TARDBP CHMP2B

4.69e-0410462MP:0000799
MousePhenoabnormal primary motor cortex morphology

TARDBP CHMP2B

4.69e-0410462MP:0012448
MousePhenopericardial effusion

FOXO1 NCOA6 IFT88 EP300

4.75e-04111464MP:0005312
DomainNuc_rcpt_coact

NCOA1 CREBBP EP300

4.80e-076553IPR009110
DomainSnf7_fam

CHMP3 CHMP2A CHMP2B

5.22e-0612553IPR005024
DomainSnf7

CHMP3 CHMP2A CHMP2B

5.22e-0612553PF03357
DomainBCL9_beta-catenin-bd_dom

BCL9L BCL9

8.51e-062552IPR024670
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

8.51e-062552IPR014744
DomainHAT_KAT11

CREBBP EP300

8.51e-062552PF08214
DomainKIX

CREBBP EP300

8.51e-062552PS50952
DomainBCL9

BCL9L BCL9

8.51e-062552PF11502
DomainZnF_TAZ

CREBBP EP300

8.51e-062552SM00551
DomainCBP_P300_HAT

CREBBP EP300

8.51e-062552IPR031162
DomainDUF902

CREBBP EP300

8.51e-062552PF06001
Domain-

CREBBP EP300

8.51e-0625521.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

8.51e-062552IPR010303
Domain-

CREBBP EP300

8.51e-0625521.10.1630.10
DomainCreb_binding

CREBBP EP300

8.51e-062552PF09030
Domain-

CREBBP EP300

8.51e-0625521.10.246.20
Domainzf-TAZ

CREBBP EP300

8.51e-062552PF02135
DomainZF_TAZ

CREBBP EP300

8.51e-062552PS50134
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

8.51e-062552IPR013178
DomainKAT11

CREBBP EP300

8.51e-062552SM01250
DomainZnf_TAZ

CREBBP EP300

8.51e-062552IPR000197
DomainKIX_dom

CREBBP EP300

8.51e-062552IPR003101
DomainKIX

CREBBP EP300

8.51e-062552PF02172
DomainBcl-9

BCL9L BCL9

8.51e-062552IPR015668
DomainCBP_P300_HAT

CREBBP EP300

8.51e-062552PS51727
DomainSki_Sno

DACH2 DACH1

1.77e-047552PF02437
Domain-

DACH2 DACH1

1.77e-0475523.10.260.20
DomainTransform_Ski

DACH2 DACH1

1.77e-047552IPR003380
DomainDNA-bd_dom_put

DACH2 DACH1

4.60e-0411552IPR009061
DomainZZ

CREBBP EP300

1.26e-0318552PF00569
DomainZF_ZZ_2

CREBBP EP300

1.26e-0318552PS50135
DomainZF_ZZ_1

CREBBP EP300

1.26e-0318552PS01357
DomainZnf_ZZ

CREBBP EP300

1.41e-0319552IPR000433
DomainZnF_ZZ

CREBBP EP300

1.41e-0319552SM00291
DomainPAS

AHR NCOA1

2.45e-0325552PF00989
DomainPAS_fold

AHR NCOA1

2.45e-0325552IPR013767
DomainBromodomain_CS

CREBBP EP300

2.64e-0326552IPR018359
DomainPAS

AHR NCOA1

3.99e-0332552SM00091
DomainPAS

AHR NCOA1

4.50e-0334552IPR000014
DomainPAS

AHR NCOA1

4.50e-0334552PS50112
DomainBROMODOMAIN_1

CREBBP EP300

5.31e-0337552PS00633
DomainBromodomain

CREBBP EP300

5.59e-0338552PF00439
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA6 NCOA1 CREBBP EP300

1.65e-0718404M26942
PathwayREACTOME_PYROPTOSIS

CHMP3 CASP4 CHMP2A CHMP2B

5.67e-0724404MM15212
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L RUVBL1 BCL9 EP300

7.94e-0726404MM14793
PathwayREACTOME_PYROPTOSIS

CHMP3 CASP4 CHMP2A CHMP2B

9.30e-0727404M41804
PathwayBIOCARTA_PPARG_PATHWAY

NCOA1 CREBBP EP300

1.17e-068403M22058
PathwayREACTOME_LATE_ENDOSOMAL_MICROAUTOPHAGY

IFT88 CHMP3 CHMP2A CHMP2B

2.42e-0634404M27942
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

FOXO1 CREBBP EP300

2.51e-0610403M27945
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L RUVBL1 BCL9 CREBBP EP300

5.52e-0691405M27101
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

FOXO1 CREBBP MAML3 EP300

5.75e-0642404M17541
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP MAML3 EP300

7.54e-0614403M27808
PathwayREACTOME_TRANSLATION_OF_REPLICASE_AND_ASSEMBLY_OF_THE_REPLICATION_TRANSCRIPTION_COMPLEX

CHMP3 CHMP2A CHMP2B

7.54e-0614403M39008
PathwayWP_IL6_SIGNALING_PATHWAY

FOXO1 JAK2 NCOA1 CREBBP EP300

8.78e-06100405MM15826
PathwayPID_HES_HEY_PATHWAY

JAK2 NCOA1 CREBBP EP300

9.88e-0648404M288
PathwayREACTOME_HEME_SIGNALING

NCOA6 NCOA1 CREBBP EP300

1.07e-0549404M41832
PathwayREACTOME_SIGNALING_BY_NOTCH3

WWP2 CREBBP MAML3 EP300

1.07e-0549404M618
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

CREBBP MAML3 EP300

1.16e-0516403M27121
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

FOXO1 CREBBP EP300

1.16e-0516403M27940
PathwayPID_AR_TF_PATHWAY

FOXO1 NCOA1 CREBBP EP300

1.47e-0553404M151
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

NCOA6 AHR NCOA1 CREBBP EP300

1.96e-05118405M27316
PathwayREACTOME_REGULATED_NECROSIS

CHMP3 CASP4 CHMP2A CHMP2B

2.26e-0559404M41803
PathwayREACTOME_REGULATED_NECROSIS

CHMP3 CASP4 CHMP2A CHMP2B

2.26e-0559404MM15169
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP MAML3 EP300

2.33e-0520403M27881
PathwayBIOCARTA_VDR_PATHWAY

NCOA1 CREBBP EP300

4.11e-0524403M13404
PathwayREACTOME_CIRCADIAN_CLOCK

NCOA6 NCOA1 CREBBP EP300

4.45e-0570404M938
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP MAML3 EP300

4.66e-0525403M27880
PathwayPID_HDAC_CLASSIII_PATHWAY

FOXO1 CREBBP EP300

5.26e-0526403M32
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

NCOA6 NCOA1 CREBBP

5.91e-0527403M26943
PathwayREACTOME_SEALING_OF_THE_NUCLEAR_ENVELOPE_NE_BY_ESCRT_III

CHMP3 CHMP2A CHMP2B

5.91e-0527403MM15674
PathwayREACTOME_BUDDING_AND_MATURATION_OF_HIV_VIRION

CHMP3 CHMP2A CHMP2B

6.60e-0528403M26982
PathwayPID_MYC_ACTIV_PATHWAY

CAD RUVBL1 CREBBP EP300

7.16e-0579404M66
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

7.81e-055402MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

7.81e-055402M48020
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

7.81e-055402M48023
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

7.81e-055402M27228
PathwayPID_RETINOIC_ACID_PATHWAY

NCOA1 CREBBP EP300

8.15e-0530403M207
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

FOXO1 NCOA1 CREBBP EP300

8.29e-0582404M2
PathwayREACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT

CHMP3 CHMP2A CHMP2B

9.00e-0531403M1009
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

FOXO1 NCOA6 NCOA1

9.00e-0531403M39476
PathwayREACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT

CHMP3 CHMP2A CHMP2B

9.00e-0531403MM15637
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

NCOA6 NCOA1 CREBBP EP300

9.10e-0584404M1008
PathwayREACTOME_SEALING_OF_THE_NUCLEAR_ENVELOPE_NE_BY_ESCRT_III

CHMP3 CHMP2A CHMP2B

9.92e-0532403M29848
PathwayKEGG_PROSTATE_CANCER

FOXO1 CREBBP EP300 CREB5

1.14e-0489404M13191
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

1.17e-046402M22062
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

FOXO1 EP300

1.17e-046402MM15660
PathwayWP_ANDROGEN_RECEPTOR_SIGNALING

FOXO1 NCOA1 CREBBP EP300

1.24e-0491404M39700
PathwayREACTOME_NR1H3_NR1H2_REGULATE_GENE_EXPRESSION_LINKED_TO_CHOLESTEROL_TRANSPORT_AND_EFFLUX

NCOA1 TNRC6C EP300

1.54e-0437403M29790
PathwayREACTOME_EARLY_SARS_COV_2_INFECTION_EVENTS

CHMP3 CHMP2A CHMP2B

1.54e-0437403M45028
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.63e-047402MM1573
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

NCOA6 IFT88 IQCB1 NCOA1 HAUS2 CREBBP

1.75e-04297406M27050
PathwayREACTOME_SIGNALING_BY_NOTCH

WWP2 MAML3 EP300

1.80e-0439403MM14604
PathwayPID_IFNG_PATHWAY

JAK2 CREBBP EP300

1.94e-0440403M161
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

2.17e-048402M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

2.17e-048402M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

2.17e-048402M46443
PathwayREACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP

NCOA6 NCOA1 CREBBP

2.25e-0442403M27172
PathwayWP_IL6_SIGNALING

JAK2 NCOA1 CREBBP

2.41e-0443403M39656
PathwayREACTOME_ADIPOGENESIS

NCOA6 NCOA1 CREBBP EP300

2.58e-04110404M48259
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

NCOA1 CREBBP EP300

2.59e-0444403M27295
PathwayWP_ARYL_HYDROCARBON_RECEPTOR_PATHWAY_WP2873

AHR NCOA1 EP300

2.77e-0445403M39615
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

2.79e-049402M47451
PathwayREACTOME_SIGNALING_BY_WNT

BCL9L RUVBL1 TNRC6C BCL9 CREBBP EP300

3.08e-04330406M7847
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

NCOA1 TNRC6C EP300

3.15e-0447403M29777
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

CREBBP MAML3 EP300

3.15e-0447403M7946
PathwayWP_ENERGY_METABOLISM

FOXO1 NCOA1 EP300

3.35e-0448403M39590
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP MAML3 EP300

3.35e-0448403M611
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

MAML3 EP300

3.48e-0410402MM15535
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

TNRC6C CREBBP MAML3 EP300

3.49e-04119404M607
PathwayPID_FOXO_PATHWAY

FOXO1 CREBBP EP300

3.56e-0449403M136
PathwayBIOCARTA_PPARA_PATHWAY

NCOA1 CREBBP EP300

4.25e-0452403M2404
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

4.25e-0411402MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

4.25e-0411402M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

4.25e-0411402M26924
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

BCL9L RUVBL1 BCL9 CREBBP EP300

4.85e-04233405M27099
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

NCOA6 NCOA1 CREBBP

5.01e-0455403M27145
PathwayREACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF

NCOA6 NCOA1 CREBBP

5.01e-0455403M27001
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

5.09e-0412402M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

5.09e-0412402M27765
PathwayREACTOME_NOTCH2_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

MAML3 EP300

5.09e-0412402M27159
PathwayREACTOME_SIGNALING_BY_NOTCH1_PEST_DOMAIN_MUTANTS_IN_CANCER

CREBBP MAML3 EP300

5.86e-0458403M29616
PathwayKEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_CREB_MEDIATED_TRANSCRIPTION

CREBBP CREB5

6.00e-0413402M47595
PathwayREACTOME_NR1H2_AND_NR1H3_MEDIATED_SIGNALING

NCOA1 EP300

6.00e-0413402MM15622
PathwayREACTOME_SIGNALING_BY_NOTCH

WWP2 TNRC6C CREBBP MAML3 EP300

6.21e-04246405M10189
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

NCOA6 NCOA1 CREBBP

6.47e-0460403M41830
PathwayWP_NOTCH_SIGNALING_WP61

JAK2 MAML3 EP300

6.80e-0461403M39540
PathwayREACTOME_PROGRAMMED_CELL_DEATH

CHMP3 CASP4 CHMP2A CHMP2B

6.81e-04142404MM15178
PathwayREACTOME_HATS_ACETYLATE_HISTONES

RUVBL1 NCOA1 CREBBP EP300

6.81e-04142404M27233
PathwayREACTOME_SARS_COV_1_INFECTION

CHMP3 CHMP2A EP300 CHMP2B

6.99e-04143404M39006
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

8.05e-0415402MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

8.05e-0415402M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

8.05e-0415402MM1439
PathwayWP_RUBINSTEINTAYBI_SYNDROME_1

FOXO1 CREBBP

8.05e-0415402M48323
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

8.05e-0415402M953
PathwayREACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION

NCOA1 TNRC6C CREBBP EP300

8.15e-04149404M27888
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

CREBBP MAML3 EP300

8.18e-0465403M39682
PathwayPID_HIF1_TFPATHWAY

NCOA1 CREBBP EP300

8.56e-0466403M255
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

FOXO1 CREBBP EP300

8.56e-0466403M27938
PathwayWP_HEPATITIS_B_INFECTION

JAK2 CREBBP EP300 CREB5

8.57e-04151404M39801
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

9.19e-0416402M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

9.19e-0416402MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

9.19e-0416402M8516
Pubmed

DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells.

FOXO1 NCOA1 CREBBP EP300

1.56e-10664410973497
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

NCOA6 NCOA1 CREBBP EP300

5.10e-091264412189208
Pubmed

Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.

NCOA1 CREBBP EP300

2.37e-08464312208951
Pubmed

The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation.

NCOA1 CREBBP EP300

2.37e-08464311463834
Pubmed

ESCRT-III CHMP2A and CHMP3 form variable helical polymers in vitro and act synergistically during HIV-1 budding.

CHMP3 CHMP2A CHMP2B

2.37e-08464323051622
Pubmed

Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1.

NCOA1 CREBBP EP300

2.37e-08464311113179
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

NCOA6 NCOA1 CREBBP EP300

4.94e-082064411877444
Pubmed

A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP.

NCOA1 CREBBP EP300

5.93e-08564314722092
Pubmed

Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation.

NCOA6 CREBBP EP300

5.93e-08564311912212
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA6 NCOA1 CREBBP EP300

6.09e-082164419596656
Pubmed

Temporal/spatial expression of nuclear receptor coactivators in the mouse lung.

NCOA1 CREBBP EP300

1.18e-07664311076796
Pubmed

Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation.

NCOA1 CREBBP EP300

1.18e-07664310497212
Pubmed

CBP-mediated FOXO-1 acetylation inhibits pancreatic tumor growth by targeting SirT.

FOXO1 CREBBP EP300

1.18e-07664324419059
Pubmed

Role of CBP in regulating HIF-1-mediated activation of transcription.

NCOA1 CREBBP EP300

1.18e-07664315615775
Pubmed

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.

NCOA1 CREBBP EP300

2.07e-0776439590696
Pubmed

Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-alpha with coactivators contributes to its ability to regulate gene expression.

NCOA1 CREBBP EP300

3.31e-07864317475621
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

BCL9L RUVBL1 CREBBP EP300

4.64e-073464430894540
Pubmed

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.

NCOA1 CREBBP EP300

7.07e-071064330595551
Pubmed

Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation.

NCOA1 CREBBP EP300

9.70e-071164310454579
Pubmed

Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission.

CHMP3 CHMP2A CHMP2B

9.70e-071164336107470
Pubmed

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease.

CHMP3 CHMP2A CHMP2B

9.70e-071164317984323
Pubmed

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

NCOA1 CREBBP EP300

9.70e-071164315681609
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

BCL9L NCOA6 RUVBL1 DACH1 BCL9 CREBBP EP300 CREB5

1.13e-0642564824999758
Pubmed

Structure of cellular ESCRT-III spirals and their relationship to HIV budding.

CHMP3 CHMP2A CHMP2B

1.29e-061264324878737
Pubmed

Human transcription factor protein interaction networks.

MRPS7 BCL9L TARDBP NCOA6 CAD GLYR1 UBR4 DACH1 NCOA1 TNRC6C BCL9 CREBBP EP300

1.68e-061429641335140242
Pubmed

ESCRT machinery is required for plasma membrane repair.

CHMP3 CHMP2A CHMP2B

1.68e-061364324482116
Pubmed

The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

CHMP3 CHMP2A CHMP2B

1.68e-061364316554368
Pubmed

ESCRT-III controls nuclear envelope reformation.

CHMP3 CHMP2A CHMP2B

2.13e-061464326040713
Pubmed

MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation.

NCOA1 CREBBP EP300

2.13e-061464317641689
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

NCOA6 NCOA1 CREBBP

2.13e-061464312482968
Pubmed

AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding.

CHMP3 CHMP2A CHMP2B

2.66e-061564314505569
Pubmed

Membrane scission by the ESCRT-III complex.

CHMP3 CHMP2A CHMP2B

2.66e-061564319234443
Pubmed

Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing.

CHMP3 CHMP2A CHMP2B

2.66e-061564326040712
Pubmed

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

NCOA6 NCOA1 CREBBP

2.66e-061564310567404
Pubmed

Recycling of ESCRTs by the AAA-ATPase Vps4 is regulated by a conserved VSL region in Vta1.

CHMP3 CHMP2A CHMP2B

2.66e-061564316505166
Pubmed

Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance.

CHMP3 CHMP2A CHMP2B

2.66e-061564320616062
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

3.33e-06264227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

3.33e-06264234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

3.33e-06264219729597
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

3.33e-06264239287984
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

3.33e-06264220717166
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

3.33e-06264225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

3.33e-06264211559821
Pubmed

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.

BCL9L BCL9

3.33e-06264215371335
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

3.33e-06264232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

3.33e-06264219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

3.33e-06264224522976
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

3.33e-06264221847097
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

3.33e-06264234813504
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

3.33e-06264220301699
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

3.33e-06264224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

3.33e-06264237816914
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

3.33e-06264211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

3.33e-06264210918613
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

3.33e-06264235502657
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

3.33e-06264231898871
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

3.33e-06264230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

3.33e-06264227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

3.33e-06264219272189
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

3.33e-06264232690000
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

3.33e-06264230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

3.33e-06264221803292
Pubmed

BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.

BCL9L BCL9

3.33e-06264233767438
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

3.33e-0626429811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

3.33e-06264224089570
Pubmed

Acetylation curtails nucleosome binding, not stable nucleosome remodeling, by FoxO1.

FOXO1 EP300

3.33e-06264219146829
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

3.33e-06264215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

3.33e-06264239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

3.33e-06264222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

3.33e-06264234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

3.33e-06264234019788
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

3.33e-06264215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

3.33e-06264229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

3.33e-06264224551300
Pubmed

Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains.

TARDBP CASP4

3.33e-06264230810811
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

3.33e-06264233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

3.33e-0626429018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

3.33e-06264224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

3.33e-06264230135524
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

3.33e-06264216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

3.33e-06264229217654
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

3.33e-06264210049825
Pubmed

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration.

BCL9L BCL9

3.33e-06264238811552
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

3.33e-06264227380996
Pubmed

The aryl hydrocarbon receptor is required for normal gonadotropin responsiveness in the mouse ovary.

AHR PCOLCE2

3.33e-06264217594909
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

3.33e-06264229170789
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

3.33e-06264221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

3.33e-06264212646247
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

3.33e-06264211867645
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

3.33e-06264211963968
Pubmed

The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization.

CHMP2A CHMP2B

3.33e-06264233832485
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

3.33e-0626429528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

3.33e-06264212696060
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

3.33e-06264236109165
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

3.33e-06264212242694
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

3.33e-06264231182547
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

3.33e-06264230635043
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

3.33e-06264227648933
Pubmed

The NCOA1-CBP-NF-κB transcriptional complex induces inflammation response and triggers endotoxin-induced myocardial dysfunction.

NCOA1 CREBBP

3.33e-06264235339471
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

3.33e-06264210610021
InteractionEGR2 interactions

BCL9L NCOA6 WWP2 NCOA1 BCL9 CREBBP EP300

4.58e-07171567int:EGR2
InteractionNCOA2 interactions

NCOA6 CAD AHR NCOA1 CREBBP EP300

2.57e-06141566int:NCOA2
InteractionNCOA1 interactions

FOXO1 NCOA6 AHR NCOA1 CREBBP EP300

3.14e-06146566int:NCOA1
InteractionPPARGC1A interactions

FOXO1 NCOA6 NCOA1 CREBBP EP300

3.20e-0682565int:PPARGC1A
InteractionRORA interactions

RUVBL1 NCOA1 CREBBP EP300

4.09e-0639564int:RORA
InteractionGSC interactions

BCL9L WWP2 BCL9 CREBBP EP300

4.29e-0687565int:GSC
InteractionTBP interactions

TARDBP NCOA6 RUVBL1 AHR NCOA1 CREBBP EP300

6.21e-06253567int:TBP
InteractionARNT interactions

FOXO1 CAD RUVBL1 AHR NCOA1 CREBBP EP300

6.54e-06255567int:ARNT
InteractionBAG2 interactions

FOXO1 SMAP1 TARDBP NCOA6 WWP2 IQCB1 SRP54 CREBBP EP300 MBNL3

7.22e-066225610int:BAG2
InteractionCHMP1A interactions

WWP2 AHR CHMP3 CHMP2A CHMP2B

8.92e-06101565int:CHMP1A
InteractionDACH1 interactions

FOXO1 DACH2 DACH1 DCK CREBBP

1.03e-05104565int:DACH1
InteractionTBXT interactions

NCOA6 CAD BCL9 CREBBP EP300

1.75e-05116565int:TBXT
InteractionBCL3 interactions

RUVBL1 NCOA1 CREBBP EP300

1.76e-0556564int:BCL3
InteractionUSP9X interactions

RUVBL1 WWP2 UBR4 IQCB1 CASP4 BCL9 TTK EP300

2.04e-05422568int:USP9X
InteractionSP7 interactions

BCL9L NCOA6 CAD NCOA1 BCL9 CREBBP EP300

2.04e-05304567int:SP7
InteractionCHMP3 interactions

AHR CHMP3 CHMP2A CHMP2B

2.82e-0563564int:CHMP3
InteractionEWSR1 interactions

BCL9L TARDBP NCOA6 CAD RUVBL1 WWP2 DACH1 BCL9 CREBBP EP300 CREB5

3.32e-059065611int:EWSR1
InteractionRARA interactions

FOXO1 NCOA6 RUVBL1 NCOA1 CREBBP EP300

3.51e-05223566int:RARA
InteractionERG interactions

NCOA6 CAD UBR4 BCL9 CREBBP EP300

3.51e-05223566int:ERG
InteractionNR6A1 interactions

NCOA1 CREBBP EP300

3.95e-0524563int:NR6A1
InteractionCHMP4A interactions

CHMP3 DCK CHMP2A CHMP2B

4.78e-0572564int:CHMP4A
InteractionCRX interactions

BCL9L SMAP1 NCOA1 BCL9 CREBBP EP300

7.24e-05254566int:CRX
InteractionSTAT2 interactions

JAK2 UBR4 CREBBP EP300

7.59e-0581564int:STAT2
InteractionCTNNB1 interactions

FOXO1 BCL9L TARDBP SHROOM3 CAD RUVBL1 WWP2 AHR BCL9 CREBBP EP300

8.78e-0510095611int:CTNNB1
InteractionNR1H4 interactions

NCOA6 NCOA1 EP300

9.52e-0532563int:NR1H4
InteractionTRERF1 interactions

CHMP3 CREBBP EP300

1.05e-0433563int:TRERF1
InteractionRB1 interactions

FOXO1 TARDBP NCOA6 UBR4 AHR CREBBP EP300

1.05e-04394567int:RB1
InteractionSOX2 interactions

MRPS7 BCL9L TARDBP NCOA6 RUVBL1 PI4KA GLYR1 WWP2 UBR4 DACH1 SRP54 BCL9 EP300

1.10e-0414225613int:SOX2
InteractionHNF4A interactions

FOXO1 NCOA6 DACH1 NCOA1 CREBBP EP300

1.12e-04275566int:HNF4A
InteractionOPA6 interactions

WWP2 EP300

1.13e-046562int:OPA6
InteractionVPS4A interactions

BNIP1 CHMP3 CHMP2A EP300

1.19e-0491564int:VPS4A
InteractionTLX1 interactions

MRPS7 DACH1 BCL9 CREBBP EP300

1.24e-04175565int:TLX1
InteractionCHMP5 interactions

SGTB CHMP3 CHMP2A CHMP2B

1.30e-0493564int:CHMP5
InteractionHOXB2 interactions

NCOA1 CREBBP EP300

1.36e-0436563int:HOXB2
InteractionCCDC6 interactions

FOXO1 CAD PI4KA IQCB1 TTK EP300

1.39e-04286566int:CCDC6
InteractionSOX9 interactions

NCOA6 BCL9 CREBBP EP300

1.53e-0497564int:SOX9
InteractionACTB interactions

FSIP2 TARDBP CAD RUVBL1 KLHL7 PI4KA PPP1R9A IQCB1 CREBBP EP300 CHMP2B

1.64e-0410835611int:ACTB
InteractionIRF7 interactions

CAD WWP2 CREBBP EP300

1.72e-04100564int:IRF7
InteractionYAP1 interactions

FOXO1 BCL9L TARDBP NCOA6 CAD RUVBL1 WWP2 DACH1 CREBBP EP300 CHMP2B

1.81e-0410955611int:YAP1
InteractionHNF1B interactions

RUVBL1 DACH1 BCL9 CREBBP EP300

1.83e-04190565int:HNF1B
InteractionTFF1 interactions

SGTB CREBBP EP300

2.01e-0441563int:TFF1
InteractionISL1 interactions

JAK2 BCL9L BCL9

2.01e-0441563int:ISL1
InteractionPPARG interactions

FOXO1 NCOA6 RUVBL1 NCOA1 CREBBP EP300

2.04e-04307566int:PPARG
InteractionMYH9 interactions

FOXO1 TARDBP SHROOM3 CAD RUVBL1 IQCB1 CASP4 CREBBP EP300

2.14e-04754569int:MYH9
InteractionJDP2 interactions

CREBBP EP300 CREB5

2.16e-0442563int:JDP2
InteractionFOS interactions

NCOA6 NCOA1 BCL9 CREBBP EP300 CREB5

2.22e-04312566int:FOS
InteractionSMAD3 interactions

FOXO1 NCOA6 WWP2 DACH1 NCOA1 CREBBP EP300

2.29e-04447567int:SMAD3
InteractionE2F1 interactions

NCOA6 AHR TTK CREBBP EP300

2.32e-04200565int:E2F1
InteractionFEV interactions

NCOA6 DACH1 BCL9 CREBBP EP300

2.48e-04203565int:FEV
InteractionSMG7 interactions

NCOA6 DACH1 NCOA1 TNRC6C BCL9 CREBBP

2.50e-04319566int:SMG7
InteractionTHRA interactions

NCOA6 NCOA1 CREBBP EP300

2.57e-04111564int:THRA
InteractionTRIP4 interactions

CAD RUVBL1 NCOA1 CREBBP EP300

2.66e-04206565int:TRIP4
InteractionHOXB3 interactions

CREBBP EP300

2.70e-049562int:HOXB3
InteractionARGFX interactions

CREBBP EP300

2.70e-049562int:ARGFX
InteractionSMARCA4 interactions

FOXO1 CAD WWP2 AHR NCOA1 CREBBP EP300

2.79e-04462567int:SMARCA4
InteractionNR3C2 interactions

NCOA1 CREBBP EP300

2.83e-0446563int:NR3C2
InteractionLDB1 interactions

BCL9L TARDBP BCL9 EP300

2.94e-04115564int:LDB1
InteractionRXRG interactions

NCOA6 DCK CREBBP

3.02e-0447563int:RXRG
InteractionTXNIP interactions

CAD RUVBL1 PI4KA WWP2 UBR4

3.04e-04212565int:TXNIP
InteractionCHMP2A interactions

TARDBP CHMP3 CHMP2A CHMP2B

3.14e-04117564int:CHMP2A
InteractionPYGO2 interactions

BCL9L BCL9 CREBBP

3.22e-0448563int:PYGO2
InteractionNR1I2 interactions

NCOA6 NCOA1 EP300

3.22e-0448563int:NR1I2
InteractionJUNB interactions

RUVBL1 CREBBP EP300 CREB5

3.24e-04118564int:JUNB
InteractionEMCN interactions

SGTB PPP1R9A

3.36e-0410562int:EMCN
InteractionFOSB interactions

CREBBP EP300 CREB5

3.42e-0449563int:FOSB
InteractionSUPT6H interactions

RUVBL1 WWP2 HAUS2 CREBBP EP300

3.60e-04220565int:SUPT6H
InteractionAR interactions

FOXO1 BCL9L TARDBP NCOA6 RUVBL1 AHR NCOA1 BCL9 CREBBP EP300

3.60e-049925610int:AR
InteractionJUP interactions

FOXO1 TARDBP CAD PI4KA IQCB1 CREBBP EP300

3.75e-04485567int:JUP
InteractionNEFH interactions

PI4KA GLYR1 HSD17B6

3.85e-0451563int:NEFH
InteractionPAX7 interactions

DACH1 BCL9 CREBBP EP300

3.92e-04124564int:PAX7
InteractionFOXO1 interactions

FOXO1 SHROOM3 DACH1 NCOA1 CREBBP EP300

3.92e-04347566int:FOXO1
InteractionRUNX2 interactions

WWP2 NCOA1 CREBBP EP300

4.16e-04126564int:RUNX2
InteractionVDR interactions

NCOA6 NCOA1 CREBBP EP300

4.29e-04127564int:VDR
InteractionSRC interactions

FOXO1 JAK2 MRPS7 NCOA6 CAD AHR CREBBP EP300

4.68e-04664568int:SRC
InteractionPAX9 interactions

BCL9L NCOA6 BCL9 EP300

4.68e-04130564int:PAX9
InteractionANAPC2 interactions

PI4KA IQCB1 TTK CREBBP EP300

4.77e-04234565int:ANAPC2
InteractionCIITA interactions

NCOA1 CREBBP EP300

4.81e-0455563int:CIITA
InteractionSTAT5A interactions

JAK2 KLHL7 NCOA1 EP300

4.82e-04131564int:STAT5A
InteractionAHR interactions

AHR CHMP3 NCOA1 EP300

4.96e-04132564int:AHR
InteractionPAX6 interactions

NCOA6 GLYR1 DACH1 BCL9 CREBBP EP300

5.20e-04366566int:PAX6
InteractionBRCA1 interactions

JAK2 TARDBP CAD RUVBL1 UBR4 AHR NCOA1 TNRC6C CREBBP EP300 CREB5

5.58e-0412495611int:BRCA1
InteractionSYNM interactions

FOXO1 TNRC6C EP300

5.63e-0458563int:SYNM
InteractionNR1H3 interactions

NCOA6 NCOA1 EP300

5.63e-0458563int:NR1H3
InteractionSMAD1 interactions

NCOA6 DACH1 CHMP3 CREBBP EP300

5.66e-04243565int:SMAD1
InteractionEYA4 interactions

NCOA1 TNRC6C BCL9 CREBBP EP300

5.66e-04243565int:EYA4
InteractionVTA1 interactions

CAD CHMP3 CHMP2A CHMP2B

5.71e-04137564int:VTA1
InteractionASCL2 interactions

NCOA6 EP300

5.80e-0413562int:ASCL2
InteractionSSBP4 interactions

BCL9L BCL9 EP300

5.92e-0459563int:SSBP4
InteractionMAF interactions

AHR CREBBP EP300

6.22e-0460563int:MAF
InteractionSMAD4 interactions

FOXO1 DACH1 AHR CHMP3 CHMP2A CREBBP EP300

6.36e-04530567int:SMAD4
InteractionGTF2B interactions

WWP2 NCOA1 CREBBP EP300

6.36e-04141564int:GTF2B
InteractionPPP1CA interactions

BCL9L CAD RUVBL1 WWP2 PPP1R9A CHMP2A CREBBP EP300

6.38e-04696568int:PPP1CA
InteractionRCN1 interactions

JAK2 SGTB PPP1R9A HAUS2 EP300

6.44e-04250565int:RCN1
InteractionETS2 interactions

NCOA1 CREBBP EP300

6.52e-0461563int:ETS2
InteractionPHGDH interactions

SMAP1 TARDBP WWP2 PM20D1 EP300 CHMP2B

6.78e-04385566int:PHGDH
InteractionHOXA10 interactions

FOXO1 CREBBP EP300

6.84e-0462563int:HOXA10
InteractionNCOA6 interactions

NCOA6 NCOA1 CREBBP EP300

7.06e-04145564int:NCOA6
InteractionDEAF1 interactions

DACH1 CREBBP EP300

7.51e-0464563int:DEAF1
InteractionEGLN3 interactions

CAD TRABD PI4KA UBR4 IQCB1 AHR SRP54 HAUS2 TTK CREBBP CREB5

7.60e-0412965611int:EGLN3
InteractionHAL interactions

TGM3 GUCY1A1 PI4KA GLYR1

7.63e-04148564int:HAL
CytobandEnsembl 112 genes in cytogenetic band chr7q11

SPDYE11 SPDYE17 SPDYE10 SPDYE13 SPDYE15 SPDYE8 SPDYE9 SPDYE12 SPDYE14

2.10e-10271669chr7q11
Cytoband7q11.23

SPDYE10 SPDYE8 SPDYE9 SPDYE14

1.22e-05976647q11.23
GeneFamilyCharged multivesicular body proteins|ESCRT-III

CHMP3 CHMP2A CHMP2B

2.75e-0773731118
GeneFamilyCharged multivesicular body proteins|ESCRT-III associated factors

CHMP3 CHMP2A CHMP2B

1.29e-0611373482
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA1 CREBBP EP300

5.26e-0617373486
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE8 SPDYE9

2.66e-0412372756
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

6.11e-041837291
GeneFamilyAtaxins|Trinucleotide repeat containing

TNRC6C MAML3

1.19e-0325372775
ToppCellIPF-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

GUCY1A1 PPP1R9A DACH1 AHR MAML3

5.65e-061836259b507547e6adf78e46e7f542cd9958224ec5826a
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SHROOM3 GUCY1A1 PPP1R9A DACH1 AHR

6.44e-06188625de7cb273899d0e0748c85f45c6b5e7f0642ab057
ToppCell(6)_ILC|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SHROOM3 GUCY1A1 PPP1R9A DACH1 AHR

6.44e-06188625f4734d5b703678670ece204a0519cf015e180a6e
ToppCellT_cells-CD56_bright_CD16-_NK_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GUCY1A1 PPP1R9A DACH1 AHR MAML3

7.32e-06193625826457e2aafdb61ead8a0a44d8cf9088d310684b
Drugglutamin

FOXO1 TARDBP TGM3 CAD WWP2 NCOA1 CREBBP EP300 CHMP2B

2.71e-06461599CID000000738
DrugAC1L7AJI

DACH1 CASP4 NCOA1 BCL9 DCK TTK EP300

4.34e-06256597CID000003750
DrugTCPOBOP

MRPS7 NCOA6 AHR NCOA1 EP300

4.76e-0695595CID000005382
DrugAC1L9DEH

JAK2 MRPS7 TARDBP BNIP1 HSD17B6 AHR CASP4 NCOA1 EP300

1.47e-05569599CID000442783
DiseaseMenke-Hennekam syndrome

CREBBP EP300

3.67e-062572cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

3.67e-062572DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

3.67e-062572cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.67e-062572C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

3.67e-062572180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

3.67e-062572cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

3.67e-062572DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

3.67e-062572C0035934
DiseaseDiffuse Large B-Cell Lymphoma

FOXO1 JAK2 CREBBP EP300

3.96e-0655574C0079744
DiseaseAdenoid Cystic Carcinoma

GUCY1A1 CREBBP MAML3 EP300

4.27e-05100574C0010606
Diseasehepatocellular carcinoma (biomarker_via_orthology)

JAK2 CAD PPP1R9A EP300

5.77e-05108574DOID:684 (biomarker_via_orthology)
DiseaseFrontotemporal dementia

TARDBP CHMP2B

7.65e-057572C0338451
DiseaseFrontotemporal Lobar Degeneration

TARDBP CHMP2B

7.65e-057572C0751072
DiseaseFrontotemporal Dementia With Motor Neuron Disease

TARDBP CHMP2B

1.02e-048572C3888102
Diseaseurea measurement

TGM3 SHROOM3

1.63e-0410572EFO_0011005
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

JAK2 CREBBP EP300

2.27e-0461573C1961102
Diseasefrontotemporal dementia (implicated_via_orthology)

TARDBP CHMP2B

2.39e-0412572DOID:9255 (implicated_via_orthology)
DiseaseLeukemia, Myelocytic, Acute

FOXO1 JAK2 CREBBP EP300

3.54e-04173574C0023467
DiseaseSitus ambiguus

BCL9L SHROOM3

3.79e-0415572C0266642
Diseaseheart disease (biomarker_via_orthology)

JAK2 EP300

4.89e-0417572DOID:114 (biomarker_via_orthology)
Diseasemean reticulocyte volume

FOXO1 JAK2 CAD TMEM217 HSD17B6 PCOLCE2 SPDYE12

8.47e-04799577EFO_0010701
DiseaseRetinitis Pigmentosa

IFT88 KLHL7 AHR

1.08e-03104573C0035334
DiseaseAmyotrophic Lateral Sclerosis With Dementia

TARDBP CHMP2B

1.44e-0329572C0393554
Diseasecreatinine measurement, glomerular filtration rate

NCOA6 SHROOM3 DACH1

1.52e-03117573EFO_0004518, EFO_0005208
DiseaseAmyotrophic Lateral Sclerosis, Guam Form

TARDBP CHMP2B

1.64e-0331572C0543859
Diseaseamyotrophic lateral sclerosis (is_implicated_in)

TARDBP CHMP2B

1.75e-0332572DOID:332 (is_implicated_in)
Diseasecoffee consumption

CPLX3 AHR

1.75e-0332572EFO_0004330

Protein segments in the cluster

PeptideGeneStartEntry
QQLCQKMKHMQVNGM

AHR

636

P35869
MQQMQQGNMGQIGQL

EP300

2231

Q09472
KAHMNSVLMGMKNQL

CHMP3

81

Q9Y3E7
MQEKQRMAGQMLLQT

CASP4

61

P49662
EKSNGLMFTNIMMQN

ABCA12

1306

Q86UK0
MTNISGQRMRMGIKN

GVINP1

1181

Q7Z2Y8
LQGSSMGQMAAQMGQ

CREBBP

2256

Q92793
AQDLIGNRNMQMMSI

DOP1A

1476

Q5JWR5
GNRNMQMMSIEILTL

DOP1A

1481

Q5JWR5
PVHQNGLSMNQMLMG

DACH1

531

Q9UI36
GLSMNQMLMGLSPNV

DACH1

536

Q9UI36
LQKMKLMAMNTLQGN

DACH2

226

Q96NX9
NNSMAQAMKGVTKAM

CHMP2A

96

O43633
QAMKGVTKAMGTMNR

CHMP2A

101

O43633
STQTKVMNSQMKMAG

CHMP2B

86

Q9UQN3
FMRMIGNDKQGQMIV

JAK2

1061

O60674
EKGSMNLMLQVNMTS

PM20D1

241

Q6GTS8
QMSVNSSIMGMQGPN

CREB5

201

Q02930
SGMVNQEMLNMSKKT

HAUS2

26

Q9NVX0
TGMTQMLQHPNQSGM

MAML3

876

Q96JK9
KQLNVQMNMSNVMGN

KIAA1109

4411

Q2LD37
KNMMSTLEINRGTMN

FSIP2

5456

Q5CZC0
GNAAKMMLIVNMVQG

GLYR1

431

Q49A26
GTTGQMSDLNKMMVQ

PI4KA

1161

P42356
LLAGFMGVMNNMRKQ

KLHL7

26

Q8IXQ5
KMMVQMISDANTAGN

PCOLCE2

121

Q9UKZ9
LMGMHQQIVPSQGQM

NCOA6

621

Q14686
PMIEQIMTNQMQGNK

NCOA6

711

Q14686
MAFMVKTMVGGQLKN

CPLX3

1

Q8WVH0
VLGQNVMMGPNSVMS

FOXO1

491

Q12778
NKMFSNAGILKMNMG

IFT88

226

Q13099
TGMTNMTQSLERMKQ

HSD17B6

211

O14756
MGSNSQMIPQKMREA

BCL9

726

O00512
QQQMLMSQKMRGPGD

BCL9L

791

Q86UU0
GLMTQQNFMLMKQRG

BCL9L

1426

Q86UU0
QMQLMLQNAQMSSLG

MBNL3

101

Q9NUK0
DNVQIGSAVMMMLQN

IQCB1

176

Q15051
GSAVMMMLQNILQIN

IQCB1

181

Q15051
LTMSQKNGGNVLQMM

DCK

71

P27707
QEQMSGMSLKQQLLG

FAM186A

831

A6NE01
ISKFTNMMMIGGNKV

MRPS7

91

Q9Y2R9
SLMGISRMMAQQVQQ

BNIP1

141

Q12981
NPNMNVNSMDMTGGL

TNRC6C

1271

Q9HCJ0
GMAGLQSMMRQFQQG

SRP54

476

P61011
QSMMRQFQQGAAGNM

SRP54

481

P61011
MMGMLASQQNQSGPS

TARDBP

336

Q13148
TQDGLSMMINRKNMV

ITIH3

751

Q06033
AQMQMSSLQMPGMNT

NCOA1

1336

Q15788
QPSTNSLGMNQMDMN

SATL1

21

Q86VE3
QVDMKQPSMSQAGMR

SATL1

46

Q86VE3
MNQVDMKQPSMSQAG

SATL1

286

Q86VE3
MKQPSMSQAGMRQSG

SATL1

291

Q86VE3
MGQILGKIMMSHQPQ

SPDYE10

1

P0DUX0
MGQILGKIMMSHQPQ

SPDYE11

1

P0DTA3
MGQILGKIMMSHQPQ

SPDYE8

1

P0DUD1
KQPDASMMQISQGMI

SHROOM3

171

Q8TF72
QNFQVLMIMNKGLGS

TGM3

36

Q08188
GGKMENMQLTLNLQT

WWP2

111

O00308
NIGNFNSMMAIISGM

RASGEF1A

306

Q8N9B8
QAVRQNGLMSGLMQM

TRABD

136

Q9H4I3
MGQILGKIMMSHQPQ

SPDYE12

1

P0DUX1
MGQILGKIMMSHQPQ

SPDYE13

1

A0A494C0Z2
MGQILGKIMMSHQPQ

SPDYE14

1

P0DUD3
MGQILGKIMMSHQPQ

SPDYE15

1

P0DUD4
MGQILGKIMMSHQPQ

SPDYE17

1

P0DUD2
LSQMNQQMAGMSISS

SMAP1

421

Q8IYB5
SSSQITGGMMQLLMN

UBQLNL

421

Q8IYU4
VILSMGGQLPNNMAM

CAD

1011

P27708
QGGQDILSMMGQLMK

RUVBL1

251

Q9Y265
TDNSGTVNQIMMMAN

TTK

46

P33981
LMQNPQVQQLMSGMM

SGTB

231

Q96EQ0
QVQQLMSGMMTNAIG

SGTB

236

Q96EQ0
MGQILGKIMMSHQPQ

SPDYE9

1

A0A494C191
MKQQQWCGMTAKMGT

TMEM217

1

Q8N7C4
SNNNSTMVMTGMRIQ

UBR4

2341

Q5T4S7
INQTFSGIMTMLNMQ

GUCY1A1

331

Q02108
NMNYVMLGKPMNNGL

MYT1L

296

Q9UL68
SNVNRIKNLFMQMGM

PPP1R9A

61

Q9ULJ8