Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionactin filament binding

MYO3A MYH6 LRPPRC XIRP2 SYNE1 CTNNA3 NEB FMNL2

3.89e-06227818GO:0051015
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNHD1 MYO3A MYH6 KIF6 MYO3B

1.19e-04118815GO:0003774
GeneOntologyMolecularFunctionactin binding

MYO3A MYH6 LRPPRC XIRP2 SYNE1 MYO3B CTNNA3 NEB FMNL2

1.38e-04479819GO:0003779
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO3A MYH6 MYO3B

4.90e-0438813GO:0000146
GeneOntologyBiologicalProcessspermatogenesis

DNHD1 RAN SYNE1 TLE3 CIP2A NXF2 MEIOSIN DRC1 APOB CFAP70 AK7 VPS13B

3.20e-057448112GO:0007283
GeneOntologyBiologicalProcessmale gamete generation

DNHD1 RAN SYNE1 TLE3 CIP2A NXF2 MEIOSIN DRC1 APOB CFAP70 AK7 VPS13B

4.04e-057628112GO:0048232
GeneOntologyCellularComponentsperm flagellum

DNHD1 RAN IFT172 NXF2 DRC1 CFAP70 FLACC1

1.80e-05214807GO:0036126
GeneOntologyCellularComponent9+2 motile cilium

DNHD1 RAN IFT172 NXF2 DRC1 CFAP70 FLACC1

3.56e-05238807GO:0097729
GeneOntologyCellularComponentfilopodium tip

MYO3A FMR1 MYO3B

5.87e-0520803GO:0032433
GeneOntologyCellularComponentmotile cilium

DNHD1 RAN IFT172 NXF2 DRC1 CFAP70 FLACC1 AK7

6.40e-05355808GO:0031514
GeneOntologyCellularComponentaxonemal dynein complex

DNHD1 DRC1 CFAP70

1.17e-0425803GO:0005858
GeneOntologyCellularComponentCORVET complex

VPS11 VPS8

3.00e-047802GO:0033263
MousePhenoabnormal heart atrium morphology

SEMA3A PDS5B MYH6 XIRP2 IFT172 PDS5A DRC1 CMYA5

1.28e-05232668MP:0003105
DomainARM-type_fold

PDS5B VPS11 PIK3C2G CEBPZ IFT172 CIP2A SCYL3 VEPH1 PDS5A UTP20 APOB FMNL2 PPP4R3A

2.28e-093398113IPR016024
DomainHEAT_REPEAT

PDS5B SCYL3 PDS5A UTP20

2.42e-0470814PS50077
DomainIQ

MYO3A MYH6 RASGRF1 MYO3B

2.56e-0471814PF00612
DomainIQ

MYO3A MYH6 RASGRF1 MYO3B

4.24e-0481814SM00015
DomainMyosin_head_motor_dom

MYO3A MYH6 MYO3B

5.94e-0438813IPR001609
DomainMYOSIN_MOTOR

MYO3A MYH6 MYO3B

5.94e-0438813PS51456
DomainMyosin_head

MYO3A MYH6 MYO3B

5.94e-0438813PF00063
DomainMYSc

MYO3A MYH6 MYO3B

5.94e-0438813SM00242
Domain-

SEMA3A VPS11 IFT172 TLE3 VPS8 NOL11 PLXNB2

6.04e-043338172.130.10.10
DomainWD40/YVTN_repeat-like_dom

SEMA3A VPS11 IFT172 TLE3 VPS8 NOL11 PLXNB2

6.26e-04335817IPR015943
DomainIQ_motif_EF-hand-BS

MYO3A MYH6 RASGRF1 MYO3B

6.32e-0490814IPR000048
DomainIQ

MYO3A MYH6 RASGRF1 MYO3B

7.15e-0493814PS50096
DomainARM-like

PDS5B CIP2A SCYL3 PDS5A UTP20 PPP4R3A

1.13e-03270816IPR011989
DomainCullin_repeat-like_dom

CUL1 EXOC7

1.19e-0312812IPR016159
Domain-

PDS5B CIP2A SCYL3 PDS5A UTP20

2.79e-032228151.25.10.10
DomainTPR-like_helical_dom

VPS11 LRPPRC IFT172 SMG5 CFAP70

3.44e-03233815IPR011990
DomainRASGEF

RASGRF1 BCAR3

5.64e-0326812PS00720
DomainRASGEF_CAT

RASGRF1 BCAR3

6.99e-0329812PS50009
DomainRasGEF

RASGRF1 BCAR3

7.47e-0330812PF00617
Domain-

RASGRF1 BCAR3

7.47e-03308121.10.840.10
DomainRas_GEF_dom

RASGRF1 BCAR3

7.47e-0330812IPR023578
DomainRASGEF_cat_dom

RASGRF1 BCAR3

7.47e-0330812IPR001895
DomainRasGEF

RASGRF1 BCAR3

7.47e-0330812SM00147
DomainSema

SEMA3A PLXNB2

7.96e-0331812SM00630
DomainSemap_dom

SEMA3A PLXNB2

7.96e-0331812IPR001627
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK4 PDS5B PXDN IFT172 SYNE1 TLE3 VPS8 CLEC16A VPS13B

5.20e-0740782912693553
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

CUL1 DNHD1 PDS5B RAN LRPPRC KARS1 TRIM25 FMR1 CEBPZ SYNE1 NOL11 PDS5A UTP20 APOB CMYA5

1.08e-061425821530948266
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

CUL1 RAN LRPPRC KARS1 FMR1 PXDN CEBPZ SYNE1 NTHL1 UTP20 APOB BCAR3

2.28e-06949821236574265
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CUL1 LRPPRC EXOSC10 KARS1 IFT172 CIP2A NELFB NOL11 PDS5A PPP4R3A

2.63e-06638821033239621
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

LRPPRC EXOSC10 KARS1 FMR1 XIRP2 SYNE1 CMYA5 NEB JMJD1C

2.69e-0649782923414517
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

CUL1 PDS5B PTPN2 RAN EXOSC10 KARS1 TRIM25 NELFB NOL11 PDS5A BABAM2 PPP4R3A

4.49e-061014821232416067
Pubmed

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.

PDS5B PDS5A

5.49e-06282231757807
Pubmed

PDS5A and PDS5B in Cohesin Function and Human Disease.

PDS5B PDS5A

5.49e-06282234070827
Pubmed

A targeted apoB38.9 mutation in mice is associated with reduced hepatic cholesterol synthesis and enhanced lipid peroxidation.

SREBF2 APOB

5.49e-06282216455790
Pubmed

Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions.

MYO3A MYO3B

5.49e-06282227582493
Pubmed

Mouse class III myosins: kinase activity and phosphorylation sites.

MYO3A MYO3B

5.49e-06282221895655
Pubmed

PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome.

PDS5B PDS5A

5.49e-06282235986423
Pubmed

Semaphorin-3A Promotes Degradation of Fragile X Mental Retardation Protein in Growth Cones via the Ubiquitin-Proteasome Pathway.

SEMA3A FMR1

5.49e-06282232184710
Pubmed

Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.

RAN KARS1 SYNE1 CMYA5

7.13e-065282426499835
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

DOCK4 CUL1 PDS5B LRPPRC NTHL1 TLE3 NELFB PDS5A BCAR3 CMYA5 BABAM2 JMJD1C PPP4R3A

9.32e-061284821317353931
Pubmed

A cohesin-RAD21 interactome.

PDS5B RAN LRPPRC XIRP2 PDS5A APOB

1.02e-0520882622145905
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PDS5B LRPPRC KARS1 PXDN CEBPZ CIP2A SREBF2 PDS5A UTP20 EXOC7 PLXNB2

1.32e-05942821131073040
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

XIRP2 IFT172 SYNE1

1.40e-052082321689717
Pubmed

Pds5 Regulates Sister-Chromatid Cohesion and Chromosome Bi-orientation through a Conserved Protein Interaction Module.

PDS5B PDS5A

1.64e-05382228343969
Pubmed

Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin.

MYO3A MYO3B

1.64e-05382226785147
Pubmed

Plasma folate, but not homocysteine, is associated with Apolipoprotein A1 levels in a non-fortified population.

MTHFR APOB

1.64e-05382223697869
Pubmed

Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.

MYO3A MYO3B

1.64e-05382222264607
Pubmed

Pds5B is required for cohesion establishment and Aurora B accumulation at centromeres.

PDS5B PDS5A

1.64e-05382224141881
Pubmed

Nuclear import of sterol regulatory element-binding protein-2, a basic helix-loop-helix-leucine zipper (bHLH-Zip)-containing transcription factor, occurs through the direct interaction of importin beta with HLH-Zip.

RAN SREBF2

1.64e-05382210397761
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CUL1 RAN EXOSC10 KARS1 TRIM25 FMR1 CEBPZ NTHL1 NOL11 APOB DBR1 FMNL2 MTFMT

1.86e-051371821336244648
Pubmed

A protein interaction landscape of breast cancer.

DOCK4 LRPPRC TRIM25 FMR1 CIP2A PDS5A SMG5 ZMYM1 BABAM2

1.89e-0563482934591612
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

DNHD1 EXOSC10 FMR1 SYNE1 NEB VPS13B

1.99e-0523482636243803
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PDS5B LRPPRC EXOSC10 KARS1 FMR1 CEBPZ NOL11 PDS5A UTP20

2.38e-0565382922586326
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

CUL1 RAN LRPPRC EXOSC10 KARS1 TRIM25 PXDN CEBPZ CIP2A VPS8 PDS5A EXOC7 HPSE

3.10e-051440821330833792
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

CUL1 SYNE1 CTNNA3 NEB ARHGAP19

3.11e-0515282534299191
Pubmed

A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair.

CUL1 RAN KARS1 MYO3B EXOC7

3.20e-0515382527462432
Pubmed

Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.

MYO3A MYO3B

3.28e-05482226926603
Pubmed

PDS5 proteins regulate the length of axial elements and telomere integrity during male mouse meiosis.

PDS5B PDS5A

3.28e-05482232285610
Pubmed

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.

PDS5B PDS5A

3.28e-05482229217591
Pubmed

Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.

XIRP2 NEB

3.28e-05482223985323
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

PDS5B PTPN2 KARS1 TRIM25 CEBPZ NELFB NOL11 PDS5A UTP20

4.26e-0570482929955894
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CUL1 RAN EXOSC10 KARS1 FMR1 CEBPZ NTHL1 NOL11 PDS5A UTP20 BABAM2 JMJD1C

5.00e-051294821230804502
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

CUL1 PDS5B LRPPRC EXOSC10 NELFB PDS5A EXOC7 PPP4R3A

5.39e-0556082835241646
Pubmed

Fragile X mental retardation protein FMRP and the RNA export factor NXF2 associate with and destabilize Nxf1 mRNA in neuronal cells.

FMR1 NXF2

5.47e-05582217548835
Pubmed

VPS18 recruits VPS41 to the human HOPS complex via a RING-RING interaction.

VPS11 VPS8

5.47e-05582228931724
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

CUL1 PDS5B EXOSC10 KARS1 TEX30 TRIM25 TLE3 NELFB PDS5A JMJD1C PPP4R3A

5.55e-051103821134189442
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

PDS5B EXOSC10 KARS1 FMR1 CEBPZ NOL11 UTP20 EXOC7 CENPQ

7.58e-0575982935915203
Pubmed

Sororin, a substrate of the anaphase-promoting complex, is required for sister chromatid cohesion in vertebrates.

PDS5B PDS5A

8.19e-05682215837422
Pubmed

CORVET, CHEVI and HOPS - multisubunit tethers of the endo-lysosomal system in health and disease.

VPS11 VPS8

8.19e-05682231092635
Pubmed

Genetic mouse models of autism spectrum disorder present subtle heterogenous cardiac abnormalities.

FMR1 VPS13B

8.19e-05682235445787
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

RAN EXOSC10 SCYL3 NELFB PDS5A APOB FMNL2 CLEC16A SNX1

9.06e-0577782935844135
Pubmed

Genome-wide association study indicates variants associated with insulin signaling and inflammation mediate lipoprotein responses to fenofibrate.

DOCK4 JMJD1C

1.14e-04782222890011
Pubmed

Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.

MYO3A MYO3B

1.14e-04782219332056
Pubmed

Functional contribution of Pds5 to cohesin-mediated cohesion in human cells and Xenopus egg extracts.

PDS5B PDS5A

1.14e-04782215855230
Pubmed

CYP A-204C polymorphism is associated with subclinical atherosclerosis in postmenopausal women.

MTHFR APOB

1.14e-04782218665040
Pubmed

Dosage effects of cohesin regulatory factor PDS5 on mammalian development: implications for cohesinopathies.

PDS5B PDS5A

1.14e-04782219412548
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

EXOSC10 FMR1 CEBPZ SYNE1 NOL11 UTP20

1.38e-0433282625693804
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

PDS5B RAN LRPPRC EXOSC10 TRIM25 CEBPZ SYNE1 NOL11 UTP20 PLXNB2

1.47e-041024821024711643
Pubmed

The frequency of early, spontaneous miscarriage associated with the leu33pro polymorphism of Glycoprotein IIIa: a pilot study.

MTHFR APOB

1.52e-04882221039385
Pubmed

Methylenetetrahydrofolate reductase C677T polymorphism is associated with central adiposity and increased androgenicity in healthy postmenopausal women.

MTHFR APOB

1.52e-04882218728123
Pubmed

Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes.

PTPN2 CLEC16A

1.52e-04882219264985
Pubmed

Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization.

PDS5B PDS5A

1.52e-04882229867216
Pubmed

Quantitative analysis of cohesin complex stoichiometry and SMC3 modification-dependent protein interactions.

PDS5B PDS5A

1.52e-04882221699228
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CIP2A NELFB PDS5A EXOC7 FMNL2 JMJD1C PPP4R3A

1.68e-0449382715368895
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

MYO3A MYH6 LRPPRC KARS1 TRIM25 SYNE1 CMYA5 NEB SNX1

1.69e-0484482925963833
Pubmed

Fbxl17 is rearranged in breast cancer and loss of its activity leads to increased global O-GlcNAcylation.

TGFBI CUL1 PXYLP1

1.78e-044682331560077
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CLPP PTPN2 LRPPRC EXOSC10 TRIM25 CEBPZ SYNE1 CIP2A NOL11 PLXNB2 VPS13B SNX1

1.85e-041487821233957083
Pubmed

Impact of genetic polymorphisms on platelet function and aspirin resistance.

MTHFR APOB

1.96e-04982219923980
Pubmed

Mammalian CORVET is required for fusion and conversion of distinct early endosome subpopulations.

VPS11 VPS8

1.96e-04982225266290
Pubmed

Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.

PDS5B PDS5A

1.96e-04982216682347
Pubmed

Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway.

MTHFR GABBR2

1.96e-04982219744961
Pubmed

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.

PDS5B PDS5A

1.96e-04982217349791
Pubmed

APOC3, CETP, fibrinogen, and MTHFR are genetic determinants of carotid intima-media thickness in healthy men (the Stanislas cohort).

MTHFR APOB

1.96e-04982211359462
Pubmed

[APOC3, CETP, beta-fibrinogen and MTHFR are genetic determinants of carotid intim-media thickness (Stanislas cohort)].

MTHFR APOB

1.96e-04982211575217
Pubmed

Human Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophase.

PDS5B PDS5A

1.96e-04982217112726
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MRPS18A CLPP CUL1 PTPN2 LRPPRC FMR1 SYNE1 CIP2A NOL11 PLXNB2 VPS13B MTFMT

1.96e-041496821232877691
Pubmed

Scc1 sumoylation by Mms21 promotes sister chromatid recombination through counteracting Wapl.

PDS5B PDS5A

2.44e-041082222751501
Pubmed

A prospective case-control study analyzes 12 thrombophilic gene mutations in Turkish couples with recurrent pregnancy loss.

MTHFR APOB

2.44e-041082219906129
Pubmed

Phosphorylation-enabled binding of SGO1-PP2A to cohesin protects sororin and centromeric cohesion during mitosis.

PDS5B PDS5A

2.44e-041082223242214
Pubmed

Prevalence of prothrombotic polymorphisms in Greece.

MTHFR APOB

2.44e-041082219072566
Pubmed

Genetic polymorphisms associated with thrombophilia and vascular disease in women with unexplained late intrauterine fetal death: a multicenter study.

MTHFR APOB

2.44e-041082214706682
Pubmed

Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.

VPS11 VPS8

2.44e-041082226463206
Pubmed

Confirmation of the genetic association of CTLA4 and PTPN22 with ANCA-associated vasculitis.

PTPN2 CLEC16A

2.44e-041082219951419
Pubmed

Vascular at-risk genotypes and disease severity in Lebanese sickle cell disease patients.

MTHFR APOB

2.44e-041082220425806
Pubmed

A comprehensive analysis of 12 thrombophilic mutations and related parameters in patients with inflammatory bowel disease: data from Turkey.

MTHFR APOB

2.44e-041082217111197
Pubmed

Sororin mediates sister chromatid cohesion by antagonizing Wapl.

PDS5B PDS5A

2.44e-041082221111234
Pubmed

Wapl controls the dynamic association of cohesin with chromatin.

PDS5B PDS5A

2.98e-041182217113138
Pubmed

APRIN is a cell cycle specific BRCA2-interacting protein required for genome integrity and a predictor of outcome after chemotherapy in breast cancer.

PDS5B PDS5A

2.98e-041182222293751
Pubmed

Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency.

PTPN2 CLEC16A

2.98e-041182218593762
Pubmed

Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma.

CUL1 FMR1

2.98e-041182229142209
Pubmed

Transcriptome Analysis of Cardiac Hypertrophic Growth in MYBPC3-Null Mice Suggests Early Responders in Hypertrophic Remodeling.

XIRP2 CMYA5

2.98e-041182230410445
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CUL1 PDS5B RAN LRPPRC EXOSC10 KARS1 TRIM25 CEBPZ NOL11 PDS5A UTP20

3.30e-041353821129467282
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

CEBPZ TLE3 VPS8 SREBF2 ZMYM1 EXOC7 PLXNB2 CLEC16A PPP4R3A

3.31e-0492582928986522
Pubmed

Genetic influences on lipid metabolism trait variability within the Stanislas Cohort.

MTHFR APOB

3.57e-041282211714857
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

FOXP4 LRPPRC TLE3 ZMYM1 JMJD1C SNX1

3.64e-0439882635016035
Pubmed

Nucleotide sequence of mouse spermidine synthase cDNA.

SREBF2 APOB

4.21e-04138227803821
Pubmed

Genetic influences on blood pressure within the Stanislas Cohort.

MTHFR APOB

4.21e-041382215076187
Pubmed

The environmental and genetic evidence for the association of hyperlipidemia and hypertension.

SREBF2 APOB

4.21e-041382219155782
Pubmed

Genetic cardiovascular risk factors and age-related macular degeneration.

MTHFR APOB

4.21e-041382219860767
Pubmed

Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects.

MYH6 XIRP2

4.91e-041482217766470
Pubmed

Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.

MYO3A MYO3B

4.91e-041482226754646
Pubmed

The transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiation.

SEMA3A PLXNB2

4.91e-041482222955271
Pubmed

Identification of atrogin-1-targeted proteins during the myostatin-induced skeletal muscle wasting.

CLPP CUL1 MYH6 KARS1

5.07e-0415582422673621
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

PDS5B CEBPZ CIP2A NELFB NOL11 PDS5A ZMYM1 PLXNB2 JMJD1C AMIGO2

5.28e-041203821029180619
Pubmed

Candidate gene polymorphisms in cardiovascular disease: a comparative study of frequencies between a French and an Italian population.

MTHFR APOB

5.65e-041582211341749
InteractionC3orf18 interactions

PDS5B VPS11 CIP2A VPS8 PDS5A UTP20 EXOC7

3.69e-07115807int:C3orf18
InteractionGYPA interactions

DOCK4 PDS5B CIP2A VPS8 NELFB PDS5A UTP20 EXOC7

4.49e-07174808int:GYPA
InteractionSTIP1 interactions

CUL1 RAN LRPPRC EXOSC10 KARS1 TRIM25 FMR1 IFT172 CIP2A NELFB NOL11 PDS5A NEB HPSE PPP4R3A

8.44e-0610068015int:STIP1
InteractionCOMTD1 interactions

KARS1 TRIM25 CIP2A VPS8 PDS5A EXOC7 PPP4R3A

1.47e-05200807int:COMTD1
InteractionNELL1 interactions

TRIM25 PXDN APOB DBR1

2.30e-0542804int:NELL1
InteractionLRRC61 interactions

VPS11 TRIM25 CIP2A SNX1

2.77e-0544804int:LRRC61
InteractionPPME1 interactions

RAN KARS1 TRIM25 SYNE1 CMYA5 PPP4R3A

3.66e-05156806int:PPME1
InteractionSCN2B interactions

PDS5B CIP2A PDS5A UTP20 EXOC7

3.81e-0595805int:SCN2B
InteractionMRM3 interactions

CLPP CUL1 PTPN2 LRPPRC NTHL1 MTFMT

5.72e-05169806int:MRM3
InteractionSHMT2 interactions

CLPP CUL1 DNHD1 VPS11 LRPPRC FMR1 EXOC7 BABAM2 CLEC16A SNX1 MTFMT

6.67e-056718011int:SHMT2
InteractionKPNA1 interactions

CUL1 PTPN2 RAN EXOSC10 UTP20 ZMYM1 BCAR3 CLEC16A

7.61e-05351808int:KPNA1
GeneFamilyMyosins, class III|Deafness associated genes

MYO3A MYO3B

6.90e-0624821099
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

CUL1 MYO3A MYO3B HTR3B NEB

1.42e-06104825b5ca6e589f414e549f4990fe334d4ee54829b298
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 XIRP2 CTNNA3 CMYA5 NEB

1.66e-05172825ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 XIRP2 CTNNA3 CMYA5 NEB

1.66e-05172825bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 XIRP2 CTNNA3 PXYLP1 CMYA5

1.85e-051768259df7a124ebafb0087da0cda133a394275d7bed81
ToppCellIPF-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

TGFBI PXDN SLC35F3 MYO3B AMIGO2

2.60e-051898254178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G MYO3B VEPH1 PXYLP1 CMYA5

2.74e-051918253e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellCiliated-cil-3|World / Class top

KIF6 IFT172 SYNE1 CFAP70 AK7

2.81e-051928254989ebb8812b8af1870599acd932849122c05a29
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

KIF6 SYNE1 DRC1 CFAP70 AK7

2.88e-05193825ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G MYO3B VEPH1 PXYLP1 CMYA5

2.95e-0519482504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G MYO3B PXYLP1 CMYA5 PLXNB2

2.95e-051948254579b4a44f7c731553a284843c296866027d7c0e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G MYO3B VEPH1 PXYLP1 CMYA5

2.95e-0519482569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G MYO3B PXYLP1 CMYA5 PLXNB2

3.02e-051958253d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellCOVID-19-Heart-Mito_CM|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 XIRP2 CTNNA3 CMYA5 NEB

3.18e-0519782544e49943d62bfe622b40ad0460093d31540544df
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SYNE1 DRC1 CFAP70 FLACC1 AK7

3.18e-051978256865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT172 SYNE1 DRC1 CFAP70 AK7

3.18e-0519782591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT172 SYNE1 DRC1 CFAP70 AK7

3.18e-0519782522c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT172 SYNE1 DRC1 CFAP70 AK7

3.18e-051978253bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT172 SYNE1 DRC1 CFAP70 AK7

3.18e-0519782587db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

KIF6 PIK3C2G CFAP70 FLACC1 AK7

3.41e-0520082596701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

IFT172 SYNE1 DRC1 CFAP70 AK7

3.41e-052008256a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCellASK440-Epithelial|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

RASGRF1 SYNE1 VEPH1 CFAP70 FGGY

3.41e-05200825cb617e2a0ca82b470b473b8d5906bc8879c85718
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP4 TEX30 CEBPZ CENPQ

5.67e-05113824357bc20edc5bc14eab8262d52260ed1686e9dc54
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXP4 TEX30 CEBPZ CENPQ

5.67e-0511382491e73e3b93be242fef0f14eddd8085a1f1c730ef
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

MYH6 CTNNA3 APOB CMYA5

7.17e-051208243b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYH6 MEIOSIN APOB

1.85e-046082348adafeec1810bce5f118fa63d4a8ee7ab9ca0f7
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Serpinb1a_(Serpinb1a)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYH6 MEIOSIN APOB

1.85e-0460823a83afb89dbfc2e1cdfce57320d89c980bd8fb820
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

SEMA3A MYO3A BCAR3 ERMARD

1.92e-04155824e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 KIF6 XIRP2 CMYA5

2.02e-041578249021900d9b1a71210c9c414a9d165eaf399eb607
ToppCellfacs-Heart-RA-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 KIF6 XIRP2 CMYA5

2.02e-04157824c8c627ca181856cd31dba4cf073c2be659a49dc1
ToppCellCOPD-Epithelial-Aberrant_Basaloid|Epithelial / Disease state, Lineage and Cell class

TGFBI PXDN SLC35F3 AMIGO2

2.07e-041588248f66979e92f886d86cecbd26aaa0c5915c049734
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBI MYO3B UTP20 CLEC16A

2.07e-041588246811dc4f101dfa9a9cc13d949760d43aa522bf3b
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

SEMA3A XIRP2 CTNNA3 GABBR2

2.12e-041598245335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBI MYO3B UTP20 CLEC16A

2.28e-04162824d712bc31840ad1523e3dbf884acbb428a8995001
ToppCellP28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNHD1 NTHL1 PLXNB2 HPSE

2.61e-041688248c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

SLC35F3 RASGRF1 AMIGO2 ARHGAP19

2.61e-0416882400646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 XIRP2 CTNNA3 CMYA5

2.74e-041708243f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TRIM25 PXDN AK7 SNX1

2.74e-04170824c1f7f1bb8865e954bb499963d82bb51923d5d8d6
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MRPS18A NTHL1 CIP2A DBR1

2.74e-0417082412aa9bdb18f3bf6da2a25984d08fe9497e5570ed
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A HPSE AMIGO2 ARHGAP19

2.86e-04172824f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA3A HPSE AMIGO2 ARHGAP19

2.86e-041728246ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 RASGRF1 PXYLP1 GABBR2

3.05e-041758240992de1c7bffcb6890584357a7a0a8955927da6c
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 SMG5 CMYA5 FMNL2

3.12e-0417682474f851a398c7562dd713bc0d8d488c0037243112
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 XIRP2 CMYA5 JMJD1C

3.12e-04176824749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRF1 SMG5 CMYA5 FMNL2

3.12e-0417682431b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

DOCK4 TGFBI MTHFR ARHGAP19

3.19e-0417782452c2ba74a8605260a2623e7d151286e504ac4d19
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CTNNA3 APOB BCAR3 AMIGO2

3.19e-04177824928118b0ed120ec01c7d753ce523ab609ac24e5f
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

SEMA3A DOCK4 TGFBI PXYLP1

3.26e-04178824ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

3.26e-04178824de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO3A SLC35F3 BCAR3 FMNL2

3.26e-04178824a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CIP2A ERCC6L2 NEB HPSE

3.33e-04179824af03705a783e77f75c44fdfa793cfdccbf9dd91c
ToppCellfacs-GAT-Fat-3m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 DRC1 CFAP70 AK7

3.47e-04181824e97cbaafb93fdbee8e3cf4a06e6bcf121d941403
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRARP MYO3A CTNNA3 BCAR3

3.47e-0418182459527ad218e49386b04cabb97d53d2ed55a35961
ToppCellfacs-GAT-Fat-3m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 DRC1 CFAP70 AK7

3.47e-0418182411cb84528f7ca084f0a92eda4f2e18e63a428fe9
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SEMA3A PXDN SYNE1 GABBR2

3.47e-04181824c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 XIRP2 CTNNA3 CMYA5

3.47e-04181824719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

3.47e-04181824dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellfacs-GAT-Fat-3m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 DRC1 CFAP70 AK7

3.47e-041818245ffeca29e4d31a20c110d27af128ed024a79ad56
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

KIF6 DRC1 CFAP70 AK7

3.54e-04182824fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

XIRP2 CTNNA3 PXYLP1 CMYA5

3.54e-04182824287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC-tDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

TGFBI RASGRF1 CTNNA3 AMIGO2

3.54e-04182824ad5c99ec62cdab347d3a03c971d981e3b924020c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NTHL1 NELFB ZMYM1 AK7

3.62e-04183824ba7753e9fe2a6a87c5264f299ac97da2ddbda178
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIK3C2G MYO3B VEPH1 BCAR3

3.62e-04183824d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TGFBI VPS8 ERMARD AMIGO2

3.69e-04184824a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 PIK3C2G APOB NEB

3.69e-041848242cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Lung-EPCAM-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 DRC1 CFAP70 AK7

3.69e-04184824afb11ab301ef9801333dbb53ccff4bd0d44f1677
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 DRC1 CFAP70 AK7

3.69e-04184824a411c0bcb283534a1c15f22473c46b7d87e01294
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 PIK3C2G APOB NEB

3.69e-04184824ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP2 PIK3C2G APOB NEB

3.69e-041848242b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellMesenchymal_cells-Smooth_muscle|Mesenchymal_cells / Lineage and Cell class

NRARP CTNNA3 BCAR3 AMIGO2

3.69e-0418482483987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 XIRP2 CTNNA3 CMYA5

3.69e-04184824e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellChildren_(3_yrs)-Epithelial-ciliated_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

3.69e-041848245daff849625f2f41d56615569c0ed59cd733b34c
ToppCellCOVID-19-Heart-CM_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYH6 XIRP2 CTNNA3 CMYA5

3.77e-04185824549eeb521c3985bff396ea0f202db21822efa51f
ToppCellAT2_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

RASGRF1 SYNE1 GABBR2 FGGY

3.77e-041858243b3268e3f99121124e33086cac88479808d31630
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DRC1 CFAP70 FLACC1 AK7

3.77e-041858245e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellAdult-Epithelial-ciliated_cell-D175|Adult / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

3.77e-0418582430f4980dee6cd5959655f8d74049f3bfb5312611
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

3.77e-041858243e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

KIF6 DRC1 CFAP70 AK7

3.77e-0418582418a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NRARP MYO3A CTNNA3 BCAR3

3.85e-041868241e3ab663e4756975db6d802b2c6c054a94a79393
ToppCelldroplet-Lung-nan-18m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 DRC1 CFAP70 AK7

3.85e-04186824740fd06bcd3b24e6ff2ecf8080f378afc3e95084
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35F3 RASGRF1 DRC1 AK7

3.85e-0418682402fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCelldroplet-Marrow-BM-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI PLXNB2 HPSE SNX1

3.85e-04186824bcb3ac9f9b51346e0a2b0bda96d149b3c11f7883
ToppCelldroplet-Lung-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 DRC1 CFAP70 AK7

3.85e-041868245ab43a298d23238b34e898d11decf0ad81d1b14e
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

KIF6 DRC1 CFAP70 AK7

3.92e-04187824f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellfacs-Lung-EPCAM-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 DRC1 CFAP70 AK7

3.92e-04187824051b8c07d7489ce7576f6c57ce7008767ef76869
ToppCellP15-Epithelial-airway_epithelial_cell-club_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYH6 DRC1 CFAP70 AK7

3.92e-04187824a70aaae32426e9ddb1cbfbd0e0db24ccc96b9f40
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF6 DRC1 CFAP70 AK7

3.92e-04187824888856cde7a69ea2f14d590597e25b1af6383c51
ToppCellfacs-Heart-Unknown-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 XIRP2 CTNNA3 CMYA5

3.92e-041878240ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 VEPH1 GABBR2 FGGY

3.92e-0418782411670a85db87cbb3e78022a589632173604b0940
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

3.92e-041878249e10ed56090d82589bc457788282f664b70ace4b
ToppCellfacs-Heart-Unknown|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 XIRP2 CTNNA3 CMYA5

3.92e-04187824362e56426a568423a81e8a30e3ecf99b76135843
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

RASGRF1 VEPH1 GABBR2 FGGY

3.92e-041878240277d4e54bd4d48f30241c2951a569209423fee8
ToppCellfacs-Heart-Unknown-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 XIRP2 CTNNA3 CMYA5

3.92e-04187824c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH6 CTNNA3 CMYA5 NEB

4.00e-041888246d249fe92d51a19da19ec14bb2262d394255d577
ToppCelltumor_Lung-Epithelial_cells-tS3|tumor_Lung / Location, Cell class and cell subclass

DRC1 CFAP70 FLACC1 AK7

4.00e-0418882426326b4e298e33f9ba393fc632238aa8c54b1ea3
ToppCellEpithelial-ciliated_cell|World / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

4.00e-0418882461a459f3fe57e5728efc72637ff2edc2d343492b
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 XIRP2 CTNNA3 CMYA5

4.00e-0418882490dc0e15798d0b984518ad58c7e416e30aff687a
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBI RAN CIP2A ARHGAP19

4.00e-04188824a6ad6de6aeaf213952124252c1452b73942a0c3d
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

SYNE1 DRC1 CFAP70 AK7

4.00e-041888248f30535a32968a81a304315a49c0d90a77d36948
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

SEMA3A PXDN SYNE1 BCAR3

4.00e-04188824e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCellAdult-Epithelial-ciliated_cell-D231|Adult / Lineage, Cell type, age group and donor

KIF6 DRC1 CFAP70 AK7

4.00e-0418882434b11f72ca73153d02edcd09b38983ad1a504659
DiseaseMalignant neoplasm of breast

SEMA3A FOXP4 KIF6 MTHFR SYNE1 TLE3 SREBF2 UTP20 BCAR3 HPSE FLACC1 VPS13B

3.13e-0510748012C0006142
DiseaseMajor Depressive Disorder

FMR1 MTHFR HTR3B CMYA5 GABBR2 HPSE

5.30e-05243806C1269683
DiseaseUnipolar Depression

FMR1 MTHFR HTR3B CMYA5 GABBR2 HPSE

7.53e-05259806C0041696
Diseasetype 1 diabetes mellitus (is_implicated_in)

RAN MTHFR SREBF2 CLEC16A

8.58e-0585804DOID:9744 (is_implicated_in)
Diseasetype 2 diabetes mellitus (is_implicated_in)

KIF6 PIK3C2G MTHFR SREBF2 APOB

1.04e-04171805DOID:9352 (is_implicated_in)
Diseasesleep duration, triglyceride measurement

SLC35F3 APOB BABAM2 JMJD1C

1.87e-04104804EFO_0004530, EFO_0005271
Diseasevascular endothelial growth factor A, isoform 121 measurement

MRPS18A JMJD1C

2.58e-049802EFO_0020847
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

CLPP MYO3A KARS1

3.64e-0451803cv:CN043650
Diseasebone mineral content measurement

KIF6 SLC35F3 PDS5A CMYA5

4.39e-04130804EFO_0007621
Diseasevascular endothelial growth factor A measurement

MRPS18A JMJD1C

4.71e-0412802EFO_0010804
DiseaseMammary Carcinoma, Human

MTHFR SYNE1 TLE3 SREBF2 BCAR3 HPSE FLACC1

5.62e-04525807C4704874
DiseaseMammary Neoplasms, Human

MTHFR SYNE1 TLE3 SREBF2 BCAR3 HPSE FLACC1

5.62e-04525807C1257931
DiseaseMammary Neoplasms

MTHFR SYNE1 TLE3 SREBF2 BCAR3 HPSE FLACC1

5.75e-04527807C1458155
DiseaseBreast Carcinoma

MTHFR SYNE1 TLE3 SREBF2 BCAR3 HPSE FLACC1

6.49e-04538807C0678222
DiseaseHereditary hearing loss and deafness

CLPP MYO3A LRPPRC KARS1

6.80e-04146804cv:C0236038
DiseaseAutistic Disorder

DOCK4 FMR1 MTHFR GABBR2 JMJD1C

7.30e-04261805C0004352
Diseasesickle cell anemia (is_implicated_in)

MTHFR APOB

8.50e-0416802DOID:10923 (is_implicated_in)
DiseaseHypercholesterolemia, Familial

SREBF2 APOB

1.08e-0318802C0020445
DiseaseNonsyndromic genetic hearing loss

CLPP MYO3A KARS1

1.17e-0376803cv:C5680182
Diseaseprion disease

SEMA3A PXYLP1

1.20e-0319802EFO_0004720
Diseasecardiac troponin I measurement

NRARP CTNNA3 C15orf32 PLXNB2

1.36e-03176804EFO_0010071
Diseasesevere acute respiratory syndrome, COVID-19

SEMA3A PXDN PIK3C2G MYO3B DRC1 FGGY

1.37e-03447806EFO_0000694, MONDO_0100096
Diseasemean reticulocyte volume

PDS5B PTPN2 MTHFR DBR1 NEB JMJD1C PPP4R3A CENPQ

1.45e-03799808EFO_0010701
Diseasekidney disease (biomarker_via_orthology)

TGFBI SREBF2

1.47e-0321802DOID:557 (biomarker_via_orthology)
Diseasedocosahexaenoic acid to total fatty acids percentage

APOB JMJD1C

1.47e-0321802EFO_0022262
Diseaseliver fibrosis measurement

APOB BCAR3 JMJD1C

1.67e-0386803EFO_0010576
DiseaseCoronary heart disease

MTHFR APOB

1.93e-0324802C0010068
Diseasecoronary artery disease (is_implicated_in)

KIF6 MTHFR APOB

2.57e-03100803DOID:3393 (is_implicated_in)
Diseasered blood cell density measurement

SHLD2 PTPN2 MTHFR TLE3 SMG5 JMJD1C VPS13B PPP4R3A

2.65e-03880808EFO_0007978

Protein segments in the cluster

PeptideGeneStartEntry
RNHIIKDQLASKYLY

TGFBI

436

Q15582
IQYHLNFLKKRLLQQ

CENPQ

106

Q7L2Z9
HQYTQTAILYEKQLK

BCAR3

671

O75815
ALYHLSKQLLQKYHK

HTR3B

31

O95264
KVLEVLLLYNNHISY

AMIGO2

141

Q86SJ2
KQNKLYLQLYVQHWI

DNHD1

1486

Q96M86
IVFHRKKNLQYYDIS

RAN

136

P62826
IKDKLLHIYYQNSID

PDS5B

436

Q9NTI5
IKDKLLHIYYQNSID

PDS5A

446

Q29RF7
HLKYLLKTQENVYNI

PIK3C2G

416

O75747
KSYYTVHLLQLENIN

PTPN2

151

P17706
ELKQKIHQTYRVQYI

PPP4R3A

256

Q6IN85
AIVSILNYVIYKNTH

PARP9

216

Q8IXQ6
LNYVIYKNTHIKTVA

PARP9

221

Q8IXQ6
LINLYKLVKSQISVY

NOL11

671

Q9H8H0
LQVLKKYELRVNYHL

MTHFR

526

P42898
NLYYTQLELQKEKAI

FLACC1

356

Q96Q35
HQDIVLYLITKAKYA

NRARP

96

Q7Z6K4
YDDKLQVKNILYHAV

JMJD1C

2506

Q15652
NTLVALHQLYQYTQK

PLXNB2

1786

O15031
IEYQDKLYLHLKKNL

VEPH1

541

Q14D04
LYYVLHITKQRNKNA

NELFB

426

Q8WX92
KYINLSLHYLEQVII

KIF6

271

Q6ZMV9
DVSHYNALLKVYLQN

LRPPRC

161

P42704
QLQEYYKKQQEQLHL

FOXP4

141

Q8IVH2
TKKEILVHVLQYIQY

MEIOSIN

101

C9JSJ3
KAIYQLNQEKLEYNL

DRC1

306

Q96MC2
YQEQLLLREHYQKKF

HPSE

146

Q9Y251
FLHNNYNYILKSLEK

EXOC7

576

Q9UPT5
IETATKQNYKILHKY

IFT172

1431

Q9UG01
SKKHIQRDYYNTLLQ

SCYL3

476

Q8IZE3
LAYLEQIKFYSHQLK

CTNNA3

766

Q9UI47
YLELYRKQKKHLNTQ

EXOSC10

491

Q01780
KIISDYHQQFRYKLQ

APOB

4486

P04114
QNYHTFLIYITELLK

APOB

4526

P04114
ANATVLLDYHLNYLK

FMR1

411

Q06787
RYIHKLYDLHLKAQN

DOCK4

1201

Q8N1I0
LLTNKVQYVIQGYHK

BABAM2

256

Q9NXR7
YQVFLKLVEHQKEYL

FGGY

531

Q96C11
YYLVLAQTHILKKNF

CFAP70

931

Q5T0N1
YVQTVLDVHKKYNAL

CUL1

366

Q13616
YLILAQKQKTQAYLE

CMYA5

1106

Q8N3K9
KTLLNSIQHKYVFQY

GIMD1

171

P0DJR0
VIYHKQSQILLVYCK

MTFMT

311

Q96DP5
QTLLHYISNVVKEKY

FMNL2

861

Q96PY5
YISNVVKEKYHQVSL

FMNL2

866

Q96PY5
EKTTYIKQNHYQELN

GABBR2

821

O75899
YHVRNIEVYKLKQLK

DBR1

151

Q9UK59
HEYQQYLKFVKSILQ

ERMARD

611

Q5T6L9
YLSYLTVLQKVANHV

ERCC6L2

456

Q5T890
VVSKYKTLAQKLYQH

CEBPZ

201

Q03701
KTLAQKLYQHEINLF

CEBPZ

206

Q03701
ETLKHLVLQFLQQYY

NXF2

386

Q9GZY0
KLYELYLQLLLHQDQ

UTP20

936

O75691
VYYEVIQLIKTNKKH

SMG5

86

Q9UPR3
LYQHLKSSLNEYQPK

SYNE1

6731

Q8NF91
YYKIRSQAIHQLKVN

KARS1

76

Q15046
KELRTQKLYTQYHVN

FAM183A

26

A6NL82
QKLYTQYHVNPLRKI

FAM183A

31

A6NL82
VKYIKQTSAILQQHY

NTHL1

186

P78549
LLYSQHSLYLKDEKQ

SHLD2

41

Q86V20
NLKHKYNYDDVLLLS

MRPS18A

76

Q9NVS2
QYLLRLKNSQLEKTY

PXYLP1

261

Q8TE99
QITQKYQLHEVTAYL

VPS8

1061

Q8N3P4
NFIKVLKAYNQTHLY

SEMA3A

116

Q14563
ERNYHIFYQILSNKK

MYH6

281

P13533
YKIEHQAKVTQYLLD

RASGRF1

1236

Q13972
YSHHIYQQDLRKKIL

RWDD2A

161

Q9UIY3
YLYLHAIKKINTTDV

SLC35F3

166

Q8IY50
IQLLQKLTYNVKIFY

CIP2A

121

Q8TCG1
YNIYAKHTKQSLQVI

CLPP

206

Q16740
YLLSNNYVNSIIVHK

CLEC16A

116

Q2KHT3
YRSNNQVYQKLKTHL

C15orf32

71

Q32M92
KQRNLYELNRLYKHI

XIRP2

316

A4UGR9
QAYKLRVTHLYQLKQ

VPS11

81

Q9H270
NHVIKYLETLLYSQQ

SNX1

491

Q13596
YIKVILDYNTAHNKV

TRIM25

456

Q14258
RKAIDYIKYLQQVNH

SREBF2

371

Q12772
YIKYLQQVNHKLRQE

SREBF2

376

Q12772
NLKYLYLYKNEIQSI

PXDN

111

Q92626
IVHRIKAYKSVLNYL

TEX30

71

Q5JUR7
GIAQIYQLIEYLHKN

ARHGAP19

121

Q14CB8
LQAQYHSLKVEYDKL

TLE3

36

Q04726
YLSQSIELKVVQHYI

VPS13B

2736

Q7Z7G8
TAIIQYEVKYQNVKH

ZMYM1

196

Q5SVZ6
ELANYYKLHHIQLKD

AK7

386

Q96M32
TKVFLKYYHVEQLNL

MYO3A

1036

Q8NEV4
TKVFLKYYHVEQLNL

MYO3B

1041

Q8WXR4
NITNTNYKHLIHKYI

NEB

2131

P20929